13 results on '"Komppula, Mika"'
Search Results
2. Associations of Particulate Matter Sizes and Chemical Constituents with Blood Lipids: A Panel Study in Guangzhou, China
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He, Zhi-Zhou, Guo, Peng-Yue, Xu, Shu-Li, Zhou, Yang, Jalaludin, Bin, Leskinen, Ari, Knibbs, Luke D., Heinrich, Joachim, Morawska, Lidia, Yim, Steve Hung-Lam, Bui, Dinh, Komppula, Mika, Roponen, Marjut, Hu, Liwen, Chen, Gongbo, Zeng, Xiao-Wen, Yu, Yunjiang, Yang, Bo-Yi, and Dong, Guanghui
- Abstract
Existing evidence is scarce concerning the various effects of different PM sizes and chemical constituents on blood lipids. A panel study that involved 88 healthy college students with five repeated measurements (440 blood samples in total) was performed. We measured mass concentrations of particulate matter with diameters ≤ 2.5 μm (PM2.5), ≤1.0 μm (PM1.0), and ≤0.5 μm (PM0.5) as well as number concentrations of particulate matter with diameters ≤ 0.2 μm (PN0.2) and ≤0.1 μm (PN0.1). We applied linear mixed-effect models to assess the associations between short-term exposure to different PM size fractions and PM2.5constituents and seven lipid metrics. We found significant associations of greater concentrations of PM in different size fractions within 5 days before blood collection with lower high-density lipoprotein cholesterol (HDL-C) and apolipoprotein A (ApoA1) levels, higher apolipoprotein B (ApoB) levels, and lower ApoA1/ApoB ratios. Among the PM2.5constituents, we observed that higher concentrations of tin and lead were significantly associated with decreased HDL-C levels, and higher concentrations of nickel were associated with higher HDL-C levels. Our results suggest that short-term exposure to PM in different sizes was deleteriously associated with blood lipids. Some constituents, especially metals, might be the major contributors to the detrimental effects.
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- 2021
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3. Ambient air pollution in relation to diabetes and glucose-homoeostasis markers in China: a cross-sectional study with findings from the 33 Communities Chinese Health Study
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Yang, Bo-Yi, Qian, Zhengmin (Min), Li, Shanshan, Chen, Gongbo, Bloom, Michael S, Elliott, Michael, Syberg, Kevin W, Heinrich, Joachim, Markevych, Iana, Wang, Si-Quan, Chen, Da, Ma, Huimin, Chen, Duo-Hong, Liu, Yimin, Komppula, Mika, Leskinen, Ari, Liu, Kang-Kang, Zeng, Xiao-Wen, Hu, Li-Wen, Guo, Yuming, and Dong, Guang-Hui
- Abstract
Health effects of air pollution on diabetes have been scarcely studied in developing countries. We aimed to explore the associations of long-term exposure to ambient particulate matter (PM) and gaseous pollutants with diabetes prevalence and glucose-homoeostasis markers in China.
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- 2018
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4. Using Aerosol Number to Volu me Ratio in Predicting Cloud Droplet Number Concentration.
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O'Dowd, Colin D., Wagner, Paul E., Kivekäs, Niku, Kerminen, Veli-Matti, Anttila, Tatu, Hakola, Hannele, Komppula, Mika, and Lihavainen, Heikki
- Abstract
In this work we present a parameterization for estimating cloud droplet number concentration from the submicron particle volume concentration, soluble fraction, updraft velocity, and a size distribution shape parameter R (0.1 m). The parameterization will also be tested against measured values. Keywords Cloud droplet activation, parameterization [ABSTRACT FROM AUTHOR]
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- 2008
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5. Aerosol Chemical Composition in Cloud Events by High Resolution Time-of-Flight Aerosol Mass Spectrometry.
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Liqing Hao, Romakkaniemi, Sami, Kortelainen, Aki, Jaatinen, Antti, Portin, Harri, Miettinen, Pasi, Komppula, Mika, Leskinen, Ari, Virtanen, Annele, Smith, James N., Sueper, Donna, Worsnop, Douglas R., Lehtinen, Kari E. J., and Laaksonen, Ari
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- 2013
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6. Observations of aerosol-cloud interactions at the Puijo semi-urban measurement station.
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Portin, Harri J., Komppula, Mika, Leskinen, Ari P., Romakkaniemi, Sami, Laaksonen, Ari, and Lehtinen, Kari E. J.
- Abstract
The Puijo measurement station has produced continuous data on aerosol-cloud interactions since June 2006. The station is located on the top floor of an observation lower in a semi-urban environment near the town of Kuopio in central Finland. The top of the tower (306 m a.s.1.) has been detected to be in cloud approximately 10% of the time. We analysed continuous weather, particle size distribution and cloud droplet size distribution measurements. The effects of local pollutant sources and air mass origin on aerosol-cloud interaction were examined in detail. We were able to find clear evidence of file aerosol indirect effects at the Puijo site. There is a positive correlation between cloud droplet number concentration and particle number concentration. Higher cloud droplet concentration led to a smaller average cloud droplet size. Furthermore, the ratio of cloud droplet number concentration to accumulation mode particle number concentration is smaller when the particle number concentration is higher. Results from ore trajectory analysis indicated that at our site marine air masses had higher particle concentrations and the continental aerosols are more effective in acting as cloud condensation nuclei than marine aerosols, probably due to their larger mean size. We could also distinguish the effect of local pollutant sources. [ABSTRACT FROM AUTHOR]
- Published
- 2009
7. Overview of the research activities and results at Puijo semi-urban measurement station.
- Author
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Leskinen, Ari, Portin, Harri, Komppula, Mika, Miettinen, Pasi, AroIa, Antti, Lihavainen, Heikki, Hatakka, Juha, Laaksonen, Ari, and Lehtinen, Kari E. J.
- Abstract
We introduce a new measurement station that we established in 2005 in an observation tower at Puijo in Kuopio. At Puijo we measure several meteorological parameters, aerosol and cloud droplet size distribution, aerosol optical properties and trace gas concentrations. We summarize the research activities at the station during its three year history and present overall results. We compare the results from Puijo with those measured at the ground level in Kuopio and at the Finnish background stations. We also characterize the measured parameters according to the wind direction and air mass origins, based on trajectory analysis, for the effects of local and remote sources. Our conclusion is that the Puijo tower is a very good place to gather experimental data on cloud formation and aerosol-cloud interaction. In addition to cloud experiments, we would suggest the Puijo measurement station for studies of particle formation, which we also observed frequently. [ABSTRACT FROM AUTHOR]
- Published
- 2009
8. Size distributions of atmospheric ions in the Baltic Sea region.
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Komppula, Mika, Vana, Marko, Kerminen, Veli-Matti, Lihavainen, Heikki, Viisanen, Yrjö, H0rrak, Urmas, Komsaare, Kaupo, Tamm, Eduard, Hirsikko, Anne, Laakso, Lauri, and Kulmala, Markku
- Abstract
Number size distributions of air ions and aerosol particles were measured at three sites in the Baltic Sea region in spring 2004. One site was on the island of Utö in the Baltic Sea and the two other sites, Hyytiälä and Tahkuse, had a more continental location not far away from the coast of the Baltic Sea. The concentrations of cluster ions (air ions with a diameter < 1.6 nm) were about three times smaller at the Utö island as compared with those at the Hyytiälä mainland site in Finland, although the particle concentrations (i.e. ion sink) were at about the same level at these two sites. Generally, the Utö island had the lowest air-ion concentration probably due to weaker sources for ions than the other two more continentally-located stations. Intermediate ion concentrations (1.6-7 nm diameter) were generally low, even though they reached several hundreds cm
-3 during nucleation episodes. Charging probabilities of < 8 mn particles were found to be close to the steady state in all the three sites, suggesting that ion-induced nucleation was not playing a major role during tiffs time period. [ABSTRACT FROM AUTHOR]- Published
- 2007
9. Size distributions of atmospheric ions inside clouds and in cloud-free air at a remote continental site.
- Author
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Lihavainen, Heikki, Komppula, Mika, Kerminen, Veli-Matti, Järvinen, Heikki, Viisanen, Yrjö, Lehtinen, Kari, Vana, Marko, and Kulmala, Markku
- Abstract
During the late autumn 2004, aerosol and air ion number size distributions inside and out-side clouds and cloud droplet number size spectra were measured in Pallas, northern Finland. The concentrations of cluster ions (air ions with a diameter < 1.6 nm) were substantially lower, roughly by an order of magnitude, inside clouds as compared with cloud-free air. The observed concentration levels of cluster ions could be explained by a source rate of a few, ion pairs per second. The main sink for cluster ions was the cloud droplet population during the cloudy periods and the ion-ion recombination in cloud-free air. Very few, intermediate ions (1.6-7.4 nm diameter) were present during the cloudy periods, indicating that processes capable of generating intermediate ions were rather inactive inside clouds during the measurement campaign. [ABSTRACT FROM AUTHOR]
- Published
- 2007
10. PollyNET: a network of multiwavelength polarization Raman lidars
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Singh, Upendra N., Pappalardo, Gelsomina, Althausen, Dietrich, Engelmann, Ronny, Baars, Holger, Heese, Birgit, Kanitz, Thomas, Komppula, Mika, Giannakaki, Eleni, Pfüller, Anne, Silva, Ana Maria, Preißler, Jana, Wagner, Frank, Rascado, Juan Luis, Pereira, Sergio, Lim, Jae-Hyun, Ahn, Joon Young, Tesche, Matthias, and Stachlewska, Iwona S.
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- 2013
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11. Greenness around schools associated with lower risk of hypertension among children: Findings from the Seven Northeastern Cities Study in China.
- Author
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Xiao, Xiang, Yang, Bo-Yi, Hu, Li-Wen, Markevych, Iana, Bloom, Michael S., Dharmage, Shyamali C., Jalaludin, Bin, Knibbs, Luke D., Heinrich, Joachim, Morawska, Lidia, Lin, Shao, Roponen, Marjut, Guo, Yuming, Lam Yim, Steve Hung, Leskinen, Ari, Komppula, Mika, Jalava, Pasi, Yu, Hong-Yao, Zeeshan, Mohammed, and Zeng, Xiao-Wen
- Subjects
AIR pollutants ,NORMALIZED difference vegetation index ,HYPOTENSION ,BLOOD pressure ,HYPERTENSION ,OVERWEIGHT children - Abstract
Evidence suggests that residential greenness may be protective of high blood pressure, but there is scarcity of evidence on the associations between greenness around schools and blood pressure among children. We aimed to investigate this association in China. Our study included 9354 children from 62 schools in the Seven Northeastern Cities Study. Greenness around each child's school was measured by NDVI (Normalized Difference Vegetation Index) and SAVI (Soil-Adjusted Vegetation Index). Particulate matter ≤ 1 μm (PM 1) concentrations were estimated by spatiotemporal models and nitrogen dioxide (NO 2) concentrations were collected from air monitoring stations. Associations between greenness and blood pressure were determined by generalized linear and logistic mixed-effect models. Mediation by air pollution was assessed using mediation analysis. Higher greenness was consistently associated with lower blood pressure. An increase of 0.1 in NDVI corresponded to a reduction in SBP of 1.39 mmHg (95% CI: 1.86, −0.93) and lower odds of hypertension (OR = 0.76, 95% CI: 0.69, 0.82). Stronger associations were observed in children with higher BMI. Ambient PM 1 and NO 2 mediated 33.0% and 10.9% of the association between greenness and SBP, respectively. In summary, greater greenness near schools had a beneficial effect on blood pressure, particularly in overweight or obese children in China. The associations might be partially mediated by air pollution. These results might have implications for policy makers to incorporate more green space for both aesthetic and health benefits. Image 1 • Evidence on the association between greenness and blood pressure among children is scarce. • We are the first to explore this topic based on school surrounding greenness exposure. • Attending schools with higher greenness showed beneficial effects on blood pressure. • The beneficial effects were stronger in children with higher BMI levels. • Air pollution might partially mediate the effects of greenness on blood pressure. Greater greenness near schools was associated with lower blood pressure among children, which might have implications for policy makers to incorporate more green space. [ABSTRACT FROM AUTHOR]
- Published
- 2020
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12. Benefits of influenza vaccination on the associations between ambient air pollution and allergic respiratory diseases in children and adolescents: New insights from the Seven Northeastern Cities study in China.
- Author
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Liu, Kangkang, Li, Shanshan, Qian, Zhengmin (Min), Dharmage, Shyamali C., Bloom, Michael S., Heinrich, Joachim, Jalaludin, Bin, Markevych, Iana, Morawska, Lidia, Knibbs, Luke D., Hinyard, Leslie, Xian, Hong, Liu, Shan, Lin, Shao, Leskinen, Ari, Komppula, Mika, Jalava, Pasi, Roponen, Marjut, Hu, Li-Wen, and Zeng, Xiao-Wen
- Subjects
INFLUENZA vaccines ,PEDIATRIC respiratory diseases ,RHINITIS ,AIR pollution ,ALLERGIES ,AIR pollutants ,ALLERGIC rhinitis - Abstract
Little information exists on interaction effects between air pollution and influenza vaccination on allergic respiratory diseases. We conducted a large population-based study to evaluate the interaction effects between influenza vaccination and long-term exposure to ambient air pollution on allergic respiratory diseases in children and adolescents. A cross-sectional study was investigated during 2012–2013 in 94 schools from Seven Northeastern Cities (SNEC) in China. Questionnaires surveys were obtained from 56 137 children and adolescents aged 2–17 years. Influenza vaccination was defined as receipt of the influenza vaccine. We estimated air pollutants exposure [nitrogen dioxide (NO 2) and particulate matter with aerodynamic diameters ≤1 μm (PM 1), ≤2.5 μm (PM 2.5) and ≤10 μm (PM 10)] using machine learning methods. We employed two-level generalized linear mix effects model to examine interactive effects between influenza vaccination and air pollution exposure on allergic respiratory diseases (asthma, asthma-related symptoms and allergic rhinitis), after controlling for important covariates. We found statistically significant interactions between influenza vaccination and air pollutants on allergic respiratory diseases and related symptoms (doctor-diagnosed asthma, current wheeze, wheeze, persistent phlegm and allergic rhinitis). The adjusted ORs for doctor-diagnosed asthma, current wheeze and allergic rhinitis among the unvaccinated group per interquartile range (IQR) increase in PM 1 and PM 2.5 were significantly higher than the corresponding ORs among the vaccinated group [For PM 1 , doctor-diagnosed asthma: OR: 1.89 (95%CI: 1.57–2.27) vs 1.65 (95%CI: 1.36–2.00); current wheeze: OR: 1.50 (95%CI: 1.22–1.85) vs 1.10 (95%CI: 0.89–1.37); allergic rhinitis: OR: 1.38 (95%CI: 1.15–1.66) vs 1.21 (95%CI: 1.00–1.46). For PM 2.5 , doctor-diagnosed asthma: OR: 1.81 (95%CI: 1.52–2.14) vs 1.57 (95%CI: 1.32–1.88); current wheeze: OR: 1.46 (95%CI: 1.21–1.76) vs 1.11 (95%CI: 0.91–1.35); allergic rhinitis: OR: 1.35 (95%CI: 1.14–1.60) vs 1.19 (95%CI: 1.00–1.42)]. The similar patterns were observed for wheeze and persistent phlegm. The corresponding p values for interactions were less than 0.05, respectively. We assessed the risks of PM 1 -related and PM 2.5 -related current wheeze were decreased by 26.67% (95%CI: 1.04%–45.66%) and 23.97% (95%CI: 0.21%–42.08%) respectively, which was attributable to influenza vaccination (both p for efficiency <0.05). Influenza vaccination may play an important role in mitigating the detrimental effects of long-term exposure to ambient air pollution on childhood allergic respiratory diseases. Policy targeted at increasing influenza vaccination may yield co-benefits in terms of reduced allergic respiratory diseases. Image 1 • Few studies on interaction between air pollution and influenza vaccine on asthma. • A large population-based study to assess these interaction effects in China. • Influenza vaccine may mitigate the detrimental effects of air pollution on asthma. • Boys seem to be more sensitive to these interaction effects than girls. [ABSTRACT FROM AUTHOR]
- Published
- 2020
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13. Short-Term Effects of Particle Sizes and Constituents on Blood Biomarkers among Healthy Young Adults in Guangzhou, China
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Feng, Dan, Cao, Ke, He, Zhi-Zhou, Knibbs, Luke D., Jalaludin, Bin, Leskinen, Ari, Roponen, Marjut, Komppula, Mika, Jalava, Pasi, Guo, Peng-Yue, Xu, Shu-Li, Yang, Bo-Yi, Hu, Liwen, Zeng, Xiao-Wen, Chen, Gongbo, Yu, Hong-Yao, Lin, Lizi, and Dong, Guanghui
- Abstract
Evidence of the effects of various particle sizes and constituents on blood biomarkers is limited. We performed a panel study with five repeated measurements in 88 healthy college students in Guangzhou, China between December 2017 and January 2018. Mass concentrations of particles with aerodynamic diameters ≤ 2.5 μm (PM2.5), PM1, and PM0.5and number concentrations of particles with aerodynamic diameters ≤ 200 nm (PN0.2) and PN0.1were measured. We used linear mixed-effect models to explore the associations of size-fractionated particulate matter and PM2.5constituents with five blood biomarkers 0–5 days prior to blood collection. We found that an interquartile range (45.9 μg/m3) increase in PM2.5concentration was significantly associated with increments of 16.6, 3.4, 12.3, and 8.8% in C-reactive protein (CRP), monocyte chemoattractant protein-1 (MCP-1), soluble vascular cell adhesion molecule-1 (sVCAM-1), and endothelin-1(ET-1) at a 5-day lag, respectively. Similar estimates were observed for PM1, PM0.5, PN0.2, and PN0.1. For PM2.5constituents, consistent positive associations were observed between F–and sVCAM-1 and CRP and between NH4+and MCP-1, and negative associations were found between Na+and MCP-1 and ET-1, between Cl–and MCP-1, and between Mg2+and sVCAM-1. Our results suggested that both particle size and constituent exposure are significantly associated with circulating biomarkers among healthy Chinese adults. Particularly, PN0.1at a 5-day lag and F–and NH4+are the most associated with these blood biomarkers.
- Published
- 2021
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