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During the past eight years, we have been studying a group of patients whose response to gold therapy had not been satisfactory from a clinical standpoint. These patients had received various amounts of gold sodium thiosulfate both by the intravenous and by the intramuscular route. In 1931 Monash and Traub1 introduced a method of treatment for lupus erythematosus by means of intracutaneous injection of gold sodium thiosulfate and reported favorable response. The question then arose whether or not the presence of gold in lesions of lupus erythematosus under treatment with gold sodium thiosulfate had any effect in the healing of these lesions. In order to determine this point, it became desirable in this experiment to collect data with respect to the presence or absence of gold in normal skin, in active lesions and in healed lesions, as well as to study the relationship of the

Under the title "Sclerose atrophique de la peau et myosite généralisée," Petges and Clégat1 in 1906 described a case of myositis with cutaneous atrophy and poikiloderma similar to that described, about the same time, by Jacobi.2 In 1930 G. Petges and A. Petges3 reviewed the subject and reported 2 additional cases under the title "Poikilodermatomyosite."Dermatomyositis, so named by Unverricht,4 follows a course similar to the foregoing condition but lacks the poikiloderma. Numerous reports of dermatomyositis appear in the literature, and poikilodermatomyositis is discussed at length on several occasions, but actual case reports are rare. The parallelism of the condition in the case to be reported to dermatomyositis, except with reference to the superficial cutaneous changes, leads us to the belief that poikiloderma results from an unusually severe process and that dermatomyositis and poikilodermatomyositis are variants of the same process. REPORT OF A CASE Mrs. F.,

These results are presented in support of our theory that lichen planus is an infection by a specific organism. We also believe that individual susceptibility is an important factor in the production of this disease.THE ORGANISMThe organism isolated (figs. 1 to 4) is an anaerobic, nonmotile, nonencapsulated, nonspore-bearing, gram-negative bacillus, varying from about 2.5 to about 3.7 microns in length and from about 0.5 to about 0.7 microns in thickness. It is somewhat polymorphic, and not only grows sparsely but also undergoes granular degeneration, and ceases to grow after a short time on the usual varieties of mediums. Though somewhat polymorphic, it resembles organisms of the colon typhoid type, but on account of its poor growth we have been unable to classify it. The manner of growth is curious, dense clumps of various sizes being found in actively growing cultures, with relatively few individual organisms. There is

Variability in greenhouse gas emissions from reservoirs creates uncertainty in global estimates of C emissions from reservoirs. This study examines the temporal and spatial variability in CO2and CH4surface water concentrations and diffusive fluxes from an Amazonian reservoir using an original data set combining both a high temporal (1 central site × 22 years) and spatial (44 sites × 1 season) resolution monitoring. The gas concentrations at the central site decreased over time and suggested reduced bioavailability of C in the initial flooded soil but exhibited strong seasonal variation. Not accounting for this variability may result in uncertainties in estimates of annual concentrations (ranging from −68.9% to +260% for CH4and from −71.5% to +156% for CO2) and thus in estimates of diffusive gas emissions. Gas concentrations and diffusive fluxes exhibited high spatial variability in the reservoir, 24 years after impoundment. In particular, diffusive fluxes were higher in littoral and transitional areas than in open areas, suggesting a large contribution of allochthonous C to current gaseous emissions. Not accounting for this spatial variability in diffusive fluxes may underestimate the total emissions expressed in CO2equivalents from the whole reservoir by 50.7%. Our study stresses the importance of well‐resolved temporal and spatial monitoring to provide reliable estimated of C emissions and a comprehensive understanding of the processes involved; both of these inputs are needed to support decision‐making for developing energy strategies. While touted as a low carbon source of electricity, some tropical hydropower reservoirs were reported to emit substantial quantities of dioxide carbon and methane. Tropical reservoirs, especially those located in the lowland reaches of Amazon basin, are the greatest reservoir emitters on the planet. Despite this, hundreds of dams are set to be constructed in these areas. In the context of global warming and the expanding growth of hydroelectricity, the quantification of greenhouse gas emissions from tropical reservoirs is recognized as a priority. Yet emissions vary greatly in time and space. Such variability has to be addressed to provide reliable estimates of carbon emissions from reservoirs and to guide energy decision‐making. With long‐term monitoring of a 24 year old Amazonian reservoir, we reported high gaseous concentrations in the first years following impoundment due to the mineralization of the large stock of carbon coming from the flooded rainforest. The past 10 years, concentrations have significantly decreased with the reduced bioavailability of flooded carbon. Yet the variability of gaseous concentrations within the reservoir reveals the importance of carbon inputs coming from numerous tributaries and the surrounding rainforest for explaining long‐term emissions from the reservoir. Not accounting for such spatial variability may lead to significant underestimates of gross greenhouse emissions from Amazonian reservoirs. Petit‐Saut reservoir exhibited high temporal and spatial variability in dissolved CO2and CH4concentrationsVariability in dissolved gas concentrations was likely related to heterogeneity of carbon sources that also vary in time and spaceTransitional and littoral areas exhibited higher C emissions than open areas suggesting the importance of allochthonous inputs for the current gross emissions