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A 12-year-old mixed-breed dog presented with a 2-month history of abdominal distension. Radiographic examination, abdominal ultrasonography, and computed tomography revealed a mass in the cecum (15.0 × 11.9 × 4.5 cm). The cecal mass was surgically removed and examined histopathologically. Immunohistochemically, the neoplastic cells expressed S-100 and neuron specific enolase but not a-smooth muscle actin and CD117 (c-kit). These histologic and immunohistochemical features indicated that the mass was consistent with a malignant peripheral nerve sheath tumor (MPNST). In dogs, most MPNSTs arise from the brachial plexus, spinal nerve root, and skin of the extremities. However, gastrointestinal MPNSTs in dogs have not been described previously. To the best of our knowledge, this is the first report to describe cecal MPNST in a dog. [ABSTRACT FROM AUTHOR]

Objective: To evaluate differences in long-term postretention changes between adolescents and adults. Materials and Methods: The sample included 96 subjects, 51 adolescents and 45 adults (14.2 ± 0.8 and 21 .5 ± 6.8 years of age, respectively, at the end of treatment) retained for 3 years and followed approximately 16 years post treatment, who were randomly selected from two private practices. Prior to treatment, 38 and 58 had Class I and Class II malocclusions, respectively. Results: With the exception of adult midlines, all of the occlusal variables (overjet [0.50-0.77 mm], overbite [0.85-0.95 mm], the maxillary incisor irregularity [0.69-0.80 mm], the mandibular incisor irregularity [0.85-1.50 mm] and the PAR score [0.86-1 .92 points]) showed significant increases overtime. Adolescents consistently showed greater increases of the occlusal variables than adults, with mandibular incisor irregularity and the PAR index attaining statistically significant (P < .05) levels. Arch length and mandibular intercanine width showed statistically significant decreases over time in both groups; maxillary intercanine and intermolar widths did not change significantly. Overjet increased significantly more in Class II patients than in Class I patients, whereas Class I patients showed significantly greater decreases in mandibular intermolar width than Class II patients. Conclusions: Over the 16-year posttreatment period, adolescents showed significantly greater increases in mandibular incisor irregularity, and the PAR index than adults. Treated Class I patients demonstrated less increase in overjet and greater decreases in mandibular intermolar width than Class II patients. [ABSTRACT FROM AUTHOR]