30 results on '"Harle, Christopher A."'
Search Results
2. New insights about community benefit evaluation: Using the Community Health Implementation Evaluation Framework to assess what hospitals are measuring.
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Burns, Ashlyn, Yeager, Valerie A., Vest, Joshua R., Harle, Christopher A., Madsen, Emilie R., Cronin, Cory E., Singh, Simone, and Franz, Berkeley
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NONPROFIT organizations ,COMMUNITY health services ,HEALTH services accessibility ,MENTAL health ,MEDICAL quality control ,STATISTICAL sampling ,CONTENT analysis ,SEDENTARY lifestyles ,HOSPITALS ,DESCRIPTIVE statistics ,SURVEYS ,CONCEPTUAL structures ,NEEDS assessment ,PUBLIC health ,MEDICAL screening ,SOCIAL support ,HEALTH education ,MEDICAL referrals ,HEALTH care rationing ,OBESITY ,NUTRITION - Abstract
Background: Nonprofit hospitals are required to conduct community health needs assessments (CHNA) every 3 years and develop corresponding implementation plans. Implemented strategies must address the identified community needs and be evaluated for impact. Purpose: Using the Community Health Implementation Evaluation Framework (CHIEF), we assessed whether and how nonprofit hospitals are evaluating the impact of their CHNA-informed community benefit initiatives. Methodology: We conducted a content analysis of 83 hospital CHNAsthat reported evaluation outcomes drawn from a previously identified 20% random sample (n = 613) of nonprofit hospitals in the United States. Through qualitative review guided by the CHIEF, we identified and categorized the most common evaluation outcomes reported. Results: A total of 485 strategies were identified from the 83 hospitals' CHNAs. Evaluated strategies most frequently targeted behavioral health (n = 124, 26%), access (n = 83, 17%), and obesity/nutrition/inactivity (n = 68, 14%). The most common type of evaluation outcomes reported by CHIEF category included system utilization (n = 342, 71%), system implementation (n = 170, 35%), project management (n = 164, 34%), and social outcomes (n = 163, 34%). Practice Implications: CHNA evaluation strategies focus on utilization (the number of individuals served), with few focusing on social or health outcomes. This represents a missed opportunity to (a) assess the social and health impacts across individual strategies and (b) provide insight that can be used to inform the allocation of limited resources to maximize the impact of community benefit strategies. [ABSTRACT FROM AUTHOR]
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- 2024
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3. New insights about community benefit evaluation: Using the Community Health Implementation Evaluation Framework to assess what hospitals are measuring
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Burns, Ashlyn, Yeager, Valerie A., Vest, Joshua R., Harle, Christopher A., Madsen, Emilie R., Cronin, Cory E., Singh, Simone, and Franz, Berkeley
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- 2024
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4. Guidelines to manage liver transplant recipients: time for consensus?
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Harle, Christopher C.
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- 2023
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5. Mental Health‐Related Emergency Department Visits Among Children During The Early COVID‐19 Pandemic
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Edgcomb, Juliet Beni, Benson, Nicole M., Tseng, Chi‐hong, Thiruvalluru, Rohith, Pathak, Jyotishman, Bussing, Regina, Harle, Christopher A., and Zima, Bonnie T.
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To measure univariate and covariate‐adjusted trends in children's mental health‐related emergency department (MH‐ED) use across geographically diverse areas of the U.S. during the first wave of the Coronavirus‐2019 (COVID‐19) pandemic. This is a retrospective, cross‐sectional cohort study using electronic health records from four academic health systems, comparing percent volume change and adjusted risk of child MH‐ED visits among children aged 3–17 years, matched on 36‐week (3/18/19–11/25/19 vs. 3/16/20–11/22/20) and 12‐week seasonal time intervals. Adjusted incidence rate ratios (IRR) were calculated using multivariate Poisson regression. Visits declined during spring‐fall 2020 (n= 3892 vs. n= 5228, −25.5%) and during spring (n= 1051 vs. n= 1839, −42.8%), summer (n= 1430 vs. n= 1469, −2.6%), and fall (n= 1411 vs. n= 1920, −26.5%), compared with 2019. There were greater declines among males (28.2% vs. females −22.9%), children 6–12‐year (−28.6% vs. −25.9% for 3–5 years and −22.9% for 13–17 years), and Black children (−34.8% vs. −17.7% to −24.9%). Visits also declined for developmental disorders (−17.0%) and childhood‐onset disorders (e.g., attention deficit and hyperactivity disorders; −18.0%). During summer‐fall 2020, suicide‐related visits rose (summer +29.8%, fall +20.4%), but were not significantly elevated from 2019 when controlling for demographic shifts. In contrast, MH‐ED use during spring‐fall 2020 was significantly reduced for intellectual disabilities (IRR 0.62 [95% CI 0.47–0.86]), developmental disorders (IRR 0.71 [0.54–0.92]), and childhood‐onset disorders (IRR 0.74 [0.56–0.97]). The early pandemic brought overall declines in child MH‐ED use alongside co‐occurring demographic and diagnostic shifts. Children vulnerable to missed detection during instructional disruptions experienced disproportionate declines, suggesting need for future longitudinal research in this population. Children's mental health (MH)‐related Emergency department (ED) use declined during spring‐fall 2020 (−25.5%) compared with 2019, with the greatest reduction during spring (−42.8%) and fall (−26.5%), and lesser reduction during summer (−2.6%)During summer‐fall 2020, suicide‐related visits rose (summer +29.8%, fall +20.4%), but were not significantly elevated from 2019 when controlling for demographic shifts in useChildren's MH‐related ED use during spring‐fall 2020 was significantly reduced for intellectual disabilities (incidence rate ratios [IRR] 0.62 [95% CI 0.47–0.86]), developmental disorders (IRR 0.71 [0.54–0.92]), and childhood‐onset disorders (IRR 0.74 [0.56–0.97]) Children's mental health (MH)‐related Emergency department (ED) use declined during spring‐fall 2020 (−25.5%) compared with 2019, with the greatest reduction during spring (−42.8%) and fall (−26.5%), and lesser reduction during summer (−2.6%) During summer‐fall 2020, suicide‐related visits rose (summer +29.8%, fall +20.4%), but were not significantly elevated from 2019 when controlling for demographic shifts in use Children's MH‐related ED use during spring‐fall 2020 was significantly reduced for intellectual disabilities (incidence rate ratios [IRR] 0.62 [95% CI 0.47–0.86]), developmental disorders (IRR 0.71 [0.54–0.92]), and childhood‐onset disorders (IRR 0.74 [0.56–0.97])
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- 2022
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6. Increasing awareness and uptake of the MenB vaccine on a large university campus
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Richardson, Eric, Ryan, Kathleen A., Lawrence, Robert M., Harle, Christopher A., Desai, Shivani M., Livingston, Melvin D., Rawal, Amit, and Staras, Stephanie A. S.
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ABSTRACTObjective: At a large public university, we aimed to evaluate an intervention designed to increase serogroup B meningococcal (MenB) vaccine uptake and awareness.Methods:Using a pretest-posttest design with a double posttest, we evaluated an intervention conducted by a local foundation and the Florida Department of Health that distributed MenB vaccine on campus and conducted an educational campaign. Prior to intervention activities, we recruited students to complete a survey about their MenB knowledge and attitudes. For survey participants who provided contact information, we sent two follow-up surveys and assessed MenB vaccine records. We used chi-square tests, adjusted for nonindependence, to compare preintervention to postintervention (three-month and one-year) vaccination and attitudes.Results:Among the 686 students with accessible vaccine records, MenB vaccine initiation increased 9% (from 24% to 33%) and completion increased 8% (from 13% to 21%) from before the intervention to one year after the intervention. When restricting to students who completed the relevant follow-up surveys, the percentage of students who heard of the MenB vaccine increased by 15% (p> .001) from before the intervention to three months after (n = 188 students) and maintained a 10% increase (p> .001) one year after the intervention (n = 261 students). Among students that heard of the MenB vaccine, the percentage of students who thought they needed the MenB vaccine even though they received the MenACWY increased 14% (p= .03) by the three-month postintervention survey and up to 18% by the one-year follow-up (p= .002).Conclusions:A university-wide, on-campus vaccination and educational campaign increased college students’ MenB vaccine initiation, completion, and knowledge.Clinicaltrials.gov ID: NCT02975596.
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- 2021
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7. Content analysis of behavior change techniques in maternal and infant health apps
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Biviji, Rizwana, Vest, Joshua R, Dixon, Brian E, Cullen, Theresa, and Harle, Christopher A
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Maternal and infant health (MIH) mobile applications (apps) are increasingly popular and frequently used for health education and decision making. Interventions grounded in theory-based behavior change techniques (BCTs) are shown to be effective in promoting healthy behavior changes. MIH apps have the potential to be useful tools, yet the extent to which they incorporate BCTs is still unknown. The objective of this study was to assess the presence of BCTs in popular MIH apps available in the Apple App and Google Play stores. Twenty-nine popular MIH apps were coded for the presence of 16 BCTs using the mHealth app taxonomy. Popular MIH apps whose purpose was to provide health education or decision-making support to pregnant women or parents/caregivers of infants were included in the final sample. On an average, the reviewed apps included seven BCTs (range 2–16). Techniques such as personalization, review of general or specific goals, macro tailoring, self-monitoring of goals, and health behavior linkages were most frequently present. No differences in the presence of BCTs between paid and free apps were observed. Popular MIH apps typically included only a minority of BCTs found to be useful for health promotion. However, apps developed by healthcare developers incorporated a higher number of BCTs within the app content. Therefore, app developers and policymakers may consider strategies to increase health expert involvement in app design and content delivery.
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- 2021
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8. As clear as mud: new evidence regarding transfusion triggers in cardiac surgery
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Harle, Christopher and Chong, Matthew A.
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- 2020
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9. Balancing Patient-Centered and Safe Pain Care for Nonsurgical Inpatients: Clinical and Managerial Perspectives.
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Mazurenko, Olena, Andraka-Christou, Barbara T., Bair, Matthew J., Kara, Areeba Y., and Harle, Christopher A.
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- 2019
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10. Rescue Balloon Aortic Valvuloplasty After Sutureless Aortic Valve Replacement for Severe Paravalvular Leak
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Nagaoka, Eiki, Sato, Keita, Hage, Ali, Bagur, Rodrigo, Harle, Christopher, Asopa, Sanjay, and Kiaii, Bob
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Sutureless aortic valve replacement (AVR) is a wide-spreading new technology that provides short clamping time and excellent hemodynamic outcomes. However, among its possible complications is the risk of paravalvular leak. We present the case of a 63-year-old woman who underwent minimally invasive right mini-thoracotomy AVR) with Perceval S sutureless valve (LivaNova, London, UK). Intraoperative transesophageal echocardiography revealed severe paravalvular leak with stent distortion. Rescue balloon valvuloplasty was performed through the right femoral artery, and resulted in the resolution of the paravalvular leak. This case illustrates the utility and feasibility of balloon valvuloplasty in trouble-shooting sutureless aortic valve stent distortion, thus avoiding a repeat aortic cross-clamp and valve replacement.
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- 2019
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11. Balancing Patient-Centered and Safe Pain Care for Nonsurgical Inpatients: Clinical and Managerial Perspectives
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Mazurenko, Olena, Andraka-Christou, Barbara T., Bair, Matthew J., Kara, Areeba Y., and Harle, Christopher A.
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Hospitals and clinicians aim to deliver care that is safe. Simultaneously, they are ensuring that care is patient centered, meaning that it is respectful of patients’ values, preferences, and experiences. However, little is known about delivering care in cases in which these goals may not align. For example, hospitals and clinicians are facing the daunting challenge of balancing safe and patient-centered pain care for nonsurgical patients, due to lack of comprehensive care guidelines and complexity of this patient population.
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- 2019
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12. Fluid balance.
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Kirkman, Emrys, Tryphonopoulos, Peter, and Harle, Christopher
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The primary function of the lung is gas exchange between alveolar gas and the blood flowing through the nearby capillaries. This stage of gas exchange takes place by diffusion. Because gases such as oxygen diffuse relatively slowly through liquids it is essential that the fluid barrier is kept as short as possible. Furthermore, it is vital that interstitial fluid does not escape into the alveoli because this would abolish gas exchange in the flooded alveoli and lead to shunt. The net movement of these fluids is largely determined by the Starling forces. A number of physiological mechanisms normally ensure that fluid that does leave the pulmonary microvasculature is quickly removed and hence gas transfer is not impaired. The lungs, in addition, perform a number of other important non-respiratory functions, including modification of circulating levels of a range of biologically active materials, filtration of blood and serving as a reservoir of blood for rapid adjustment of input to the left atrium when needed. [ABSTRACT FROM AUTHOR]
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- 2017
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13. Reason and Timing for Conversion to Sternotomy in Robotic-Assisted Coronary Artery Bypass Grafting and Patient Outcomes
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Christidis, Nickolas K., Fox, Stephanie A., Swinamer, Stuart A., Bagur, Rodrigo, Sridhar, Kumar, Lavi, Shahar, Iglesias, Ivan, Bainbridge, Daniel, Jones, Philip M., Harle, Christopher C., Chu, Michael W. A., Teefy, Patrick, and Kiaii, Bob B.
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Objective Conversion to sternotomy is a primary bailout method for robotically assisted coronary artery bypass grafting procedures. The aims of this study were to identify the primary reasons for conversion from robotically assisted coronary artery bypass grafting to sternotomy and to evaluate the in-hospital outcomes in such patients.Methods Prospectively collected data from February 2004 to April 2017 were reviewed for 72 patients (56 men; mean age = 63.8 years) who required conversion to sternotomy during a robotically assisted coronary artery bypass grafting procedure with planned endoscopic left internal thoracic artery harvest and anastomosis to the left anterior descending on the beating heart.Results The overall rate of conversion was 12.4% (72/581). Conversions occurred either during attempted endoscopic left internal thoracic artery harvest (31.9%), during endoscopic left anterior descending isolation (40.3%), during manual isolation and anastomosis of the left anterior descending (19.4%), or after anastomosis due to unsatisfactory flow (8.3%). Overall, the most common reason for conversion was an intramyocardial left anterior descending (43.1%). The median stay in the intensive care unit was 1 day (range = 0–20) and the median hospital length of stay was 5 days (range = 3–43). In-hospital complications included new atrial fibrillation (16.7%), need for blood transfusion (20.8%), mediastinitis (4.2%), postoperative myocardial infarction (2.8%), exploration for bleeding (2.8%), and 1 in-hospital death.Conclusions The reasons for conversion were primarily related to anatomical factors that created difficulties for endoscopic left internal thoracic artery harvesting and left anterior descending identification. Patients who required conversion to sternotomy from robotically assisted coronary artery bypass grafting demonstrated acceptable outcomes and low complication rates.
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- 2018
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14. Measuring Patient Satisfaction's Relationship to Hospital Cost Efficiency: Can Administrators Make a Difference?
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Huerta, Timothy R., Harle, Christopher A., Ford, Eric W., Diana, Mark L., and Menachemi, Nir
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Objective: The aim of this study was to assess the ability and means by which hospital administrators can influence patient satisfaction and its impact on costs. Data Sources: Data are drawn from the American Hospital Association's Annual Survey of Hospitals, federally collected Hospital Cost Reports, and Medicare's Hospital Compare. Study Design: Stochastic frontier analyses (SFA) are used to test the hypothesis that the patient satisfaction--hospital cost relationship is primarily a latent ''management effect.'' The null hypothesis is that patient satisfaction measures are main effects under the control of care providers rather than administrators. Principle Findings: Both SFA models were superior to the standard regression analysis when measuring patient satisfaction's relationship to hospitals' cost efficiency. The SFA model with patient satisfaction measures treated as main effects, rather than ''latent, management effects,'' was significantly better comparing the log-likelihood statistics. Higher patient satisfaction scores on the environmental quality and provider communication dimensions were related to lower facility costs. Higher facility costs were positively associated with patients' overall impressions (willingness to recommend and overall satisfaction), assessments of medication and discharge instructions, and ratings of caregiver responsiveness (pain control and help when called). Conclusions: In the short term, managers have a limited ability to influence patient satisfaction scores, and it appears that working through frontline providers (doctors and nurses) is critical to success. In addition, results indicate that not all patient satisfaction gains are cost neutral and there may be added costs to some forms of quality. Therefore, quality is not costless as is often argued. [ABSTRACT FROM AUTHOR]
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- 2016
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15. Comparative effectiveness of dual vs. single-action antidepressants on HIV clinical outcomes in HIV-infected people with depression
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Mills, Jon C., Harman, Jeffrey S., Cook, Robert L., Marlow, Nicole M., Harle, Christopher A., Duncan, R. Paul, Gaynes, Bradley N., and Pence, Brian W.
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Supplemental Digital Content is available in the text
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- 2017
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16. Surgical treatment of carcinoid syndrome metastatic disease: Partial hepatectomy with veno-venous bypass and subsequent tricuspid valve replacement. Case report
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Giraldo, Mauricio, Harle, Christopher, Lopera-Velásquez, Luz María, and Dobkowsky, Wojciech
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Carcinoid syndrome is a relatively rare condition that may affect the liver and the right heart. Some of these cases may require surgical treatment with a multidisciplinary approach.
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- 2017
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17. Tratamiento quirúrgico de la enfermedad metastásica del síndrome carcinoide: hepatectomía parcial usando un bypass veno-venoso y posterior cambio valvular tricúspide. Reporte de caso
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Giraldo, Mauricio, Harle, Christopher, Lopera-Velásquez, Luz María, and Dobkowsky, Wojciech
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El síndrome carcinoide es una condición relativamente rara que puede afectar el hígado y el corazón derecho. En algunos pacientes se requiere tratamiento quirúrgico y un manejo multidisciplinario.
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- 2017
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18. Ultrafast Track Robotic-Assisted Minimally Invasive Coronary Artery Surgical Revascularization
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Tarola, Christopher L., Al-Amodi, Hussein A., Balasubramanian, Sankar, Fox, Stephanie A., Harle, Christopher C., Iglesias, Ivan, Sridhar, Kumar, Teefy, Patrick J., Chu, Michael W.A., and Kiaii, Bob B.
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Objective Contemporary anesthetic techniques have enabled shorter sedation and early extubation in off-pump and minimally invasive coronary artery bypass (CABG) surgery. Robotic-assisted CABG represents the optimal surgical approach for ultrafast track anesthesia, with patients able to bypass the cardiac surgical intensive care unit with recovery in the postanesthesia care unit (PACU) and inpatient ward.Methods In-hospital postoperative outcomes from ninety patients who underwent either elective or urgent robotically-assisted CABG at our institution were reviewed. These patients were carefully selected by a multidisciplinary team to undergo fast-track anesthesia: extubation in the operating room, 4-hour recovery in the postanesthesia care unit and transfer to the inpatient ward. Intrathecal, paravertebral local, and patient-controlled anesthesia techniques were used to facilitate transition to oral analgesics.Results Average patient age was 61 ± 9 years. Sixty-six patients (73%) were male. Seventy cases were elective, and 20 patients required urgent revascularization. All patients underwent intraoperative angiography after graft construction, which revealed Fitzgibbon class A grafts. There were no in-hospital mortalities. One patient required re-exploration for bleeding, through the same minimally invasive incision, did not require conversion to sternotomy for bleeding, and was transferred to the intensive care unit postexploration for bleeding for standard postoperative care. Postoperative complications were limited to one superficial wound infection. The mean hospital length of stay was 3.5 ± 1.17 days.Conclusions In patients undergoing robotic-assisted CABG, ultrafasttrack cardiac surgery with immediate postprocedure extubation and transfer to the inpatient ward has been demonstrated to be safe with no increase in perioperative morbidity or mortality. It requires a dedicated heart team with a carefully selected group of patients. Avoiding cardiac surgical intensive care unit expedites recovery, with possible avoidance of infection and early discharge from hospital.
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- 2017
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19. Ultrafast Track Robotic-Assisted Minimally Invasive Coronary Artery Surgical Revascularization
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Tarola, Christopher L., Al-Amodi, Hussein A., Balasubramanian, Sankar, Fox, Stephanie A., Harle, Christopher C., Iglesias, Ivan, Sridhar, Kumar, Teefy, Patrick J., Chu, Michael W.A., and Kiaii, Bob B.
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Objective Contemporary anesthetic techniques have enabled shorter sedation and early extubation in off-pump and minimally invasive coronary artery bypass (CABG) surgery. Robotic-assisted CABG represents the optimal surgical approach for ultrafast track anesthesia, with patients able to bypass the cardiac surgical intensive care unit with recovery in the postanesthesia care unit (PACU) and inpatient ward.Methods In-hospital postoperative outcomes from ninety patients who underwent either elective or urgent robotically-assisted CABG at our institution were reviewed. These patients were carefully selected by a multidisciplinary team to undergo fast-track anesthesia: extubation in the operating room, 4-hour recovery in the postanesthesia care unit and transfer to the inpatient ward. Intrathecal, paravertebral local, and patient-controlled anesthesia techniques were used to facilitate transition to oral analgesics.Results Average patient age was 61 ± 9 years. Sixty-six patients (73%) were male. Seventy cases were elective, and 20 patients required urgent revascularization. All patients underwent intraoperative angiography after graft construction, which revealed Fitzgibbon class A grafts. There were no in-hospital mortalities. One patient required re-exploration for bleeding, through the same minimally invasive incision, did not require conversion to sternotomy for bleeding, and was transferred to the intensive care unit postexploration for bleeding for standard postoperative care. Postoperative complications were limited to one superficial wound infection. The mean hospital length of stay was 3.5 ± 1.17 days.Conclusions In patients undergoing robotic-assisted CABG, ultrafasttrack cardiac surgery with immediate postprocedure extubation and transfer to the inpatient ward has been demonstrated to be safe with no increase in perioperative morbidity or mortality. It requires a dedicated heart team with a carefully selected group of patients. Avoiding cardiac surgical intensive care unit expedites recovery, with possible avoidance of infection and early discharge from hospital.
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- 2017
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20. Is the Future of Coronary Arterial Revascularization a Hybrid Approach?: The Canadian Experience across three Centers
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Giambruno, Vincenzo, Hafiz, Ahmad, Fox, Stephanie A., Jeanmart, Hugues, Cook, Richard C., Khaliel, Feras H., Teefy, Patrick, Sridhar, Kumar, Lavi, Shahar, Bagur, Rodrigo, Randhawa, Varinder K., Iglesias, Ivan, Jones, Philip M., Harle, Christopher C., Bainbridge, Daniel, Chu, Michael W. A., and Kiaii, Bob B.
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Objective Hybrid coronary revascularization offers and combines the advantages of both surgical and percutaneous revascularization and eliminates at the same time the disadvantages of both procedures. The objective of this study was to assess graft and stent patency at 6 months, rate of bleeding, intensive care unit and hospital stay, rate of reintervention, and long-term clinical follow-up.Methods From March 2004 to November 2015, a total of 203 patients underwent robotic-assisted minimally invasive direct coronary artery bypass graft of the left internal thoracic artery to the left anterior descending artery and PCI of a non-left anterior descending vessel in a single or two stage, at three different centers. Patients underwent 6-month angiographic follow-up. The mean ± SD clinical follow-up was 77.82 ±41.4 months.Results Successful hybrid coronary revascularization occurred in 196 of the 203 patients. One hundred forty-six patients underwent simultaneous surgical and percutaneous intervention. Nineteen patients underwent PCI before surgery, and 38 patient underwent PCI after surgery. No in-hospital mortality occurred. The mean ± SD ICU stay was 1 ± 1 days and the mean ± SD hospital stay was 5 ± 2 days. Only 13.3% of the patients required a blood transfusion. Six-month angiographic follow-up has been performed in the 95 patients, and it demonstrated a left internal thoracic artery anastomotic patency of 97.9% and stent patency of 92.6%. A total of 77.8 ± 41.4-month clinical follow-up demonstrated 95.1% survival, 92.6% freedom from angina, and 90.7% freedom from any form of coronary revascularization.Conclusions Hybrid coronary revascularization seems to be a promising and safe revascularization strategy. It provides selected patients with an alternative, functionally complete revascularization with minimal surgical trauma and good long-term clinical outcomes.
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- 2017
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21. Is the Future of Coronary Arterial Revascularization a Hybrid Approach?: The Canadian Experience across three Centers
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Giambruno, Vincenzo, Hafiz, Ahmad, Fox, Stephanie A., Jeanmart, Hugues, Cook, Richard C., Khaliel, Feras H., Teefy, Patrick, Sridhar, Kumar, Lavi, Shahar, Bagur, Rodrigo, Randhawa, Varinder K., Iglesias, Ivan, Jones, Philip M., Harle, Christopher C., Bainbridge, Daniel, Chu, Michael W. A., and Kiaii, Bob B.
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Objective Hybrid coronary revascularization offers and combines the advantages of both surgical and percutaneous revascularization and eliminates at the same time the disadvantages of both procedures. The objective of this study was to assess graft and stent patency at 6 months, rate of bleeding, intensive care unit and hospital stay, rate of reintervention, and long-term clinical follow-up.Methods From March 2004 to November 2015, a total of 203 patients underwent robotic-assisted minimally invasive direct coronary artery bypass graft of the left internal thoracic artery to the left anterior descending artery and PCI of a non-left anterior descending vessel in a single or two stage, at three different centers. Patients underwent 6-month angiographic follow-up. The mean ± SD clinical follow-up was 77.82 ±41.4 months.Results Successful hybrid coronary revascularization occurred in 196 of the 203 patients. One hundred forty-six patients underwent simultaneous surgical and percutaneous intervention. Nineteen patients underwent PCI before surgery, and 38 patient underwent PCI after surgery. No in-hospital mortality occurred. The mean ± SD ICU stay was 1 ± 1 days and the mean ± SD hospital stay was 5 ± 2 days. Only 13.3% of the patients required a blood transfusion. Six-month angiographic follow-up has been performed in the 95 patients, and it demonstrated a left internal thoracic artery anastomotic patency of 97.9% and stent patency of 92.6%. A total of 77.8 ± 41.4-month clinical follow-up demonstrated 95.1% survival, 92.6% freedom from angina, and 90.7% freedom from any form of coronary revascularization.Conclusions Hybrid coronary revascularization seems to be a promising and safe revascularization strategy. It provides selected patients with an alternative, functionally complete revascularization with minimal surgical trauma and good long-term clinical outcomes.
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- 2017
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22. Factors in Medical Student Beliefs about Electronic Health Record Use.
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Harle, Christopher A., Gruber, Laura A., and Dewar, Marvin A.
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Healthcare providers' ongoing investment in electronic health records (EHRs) necessitates an understanding of physicians' expectations about using EHRs. Such understanding may aid educators and administrators when utilizing scarce resources during EHR training and implementation activities. This study aimed to link individual medical student characteristics to their perceptions of EHRs' ease of use and usefulness. This study employed a cross-sectional survey of 126 third-year medical students at a large southeastern university. Using a questionnaire designed for this study and containing previously validated items, the study team measured and related students' expectations about EHR ease of use and usefulness to their computer self-efficacy, openness to change, personality traits, and demographic characteristics. On a seven-point scale, men reported, on average, ease-of-use scores that were 0.71 higher than women's (p < .001). Also, increased computer self-efficacy related to higher expectations of EHR ease of use (p < .01) and usefulness (p < .05). Openness-to-change scores were also associated with higher expectations of EHR ease of use (p < .01) and usefulness (p < .001). Finally, a more conscientious personality was positively associated with EHR ease of use (p < .01). Our findings suggest that medical educators and administrators may consider targeting EHR management strategies on the basis of individual differences. Enhanced training and support interventions may be helpful to women or to clinicians with lower computer self-efficacy, lower openness to change, or less conscientious personalities. Also, current and future physicians who rate higher in terms of self-efficacy, openness to change, or conscientiousness may be useful as champions of EHR use among their peers. [ABSTRACT FROM AUTHOR]
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- 2014
23. Automated Coring and Apical Connector Insertion Device for Aortic Valve Bypass Surgery.
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Adams, Corey, Guo, Linrui Ray, Jones, Philip M., Harle, Christopher, Brown, John W., Gammie, James S., and Kiaii, Bob
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AORTIC valve surgery ,SURGICAL anastomosis ,LEFT heart ventricle ,AORTIC stenosis treatment ,CORONARY artery bypass ,POSTOPERATIVE period ,BLOOD loss estimation ,FOLLOW-up studies (Medicine) - Abstract
Purpose: The technical difficulty of performing the left ventricular apical anastomosis has limited the adoption of aortic valve bypass surgery for the treatment of aortic stenosis. We report the successful use of an automated coring and apical connector device to perform aortic valve bypass surgery. Description: A 74-year-old man, with a history of prior coronary bypass surgery with patent grafts and a porcelain ascending aorta, presented with symptomatic critical aortic stenosis. Through a left anterolateral thoracotomy, a valved conduit was anastomosed to the descending thoracic aorta. The automated coring and apical connector insertion device was used to core a plug of apical myocardium and simultaneously insert an 18-mm apical connector into the left ventricular apex. Evaluation: There were no procedural complications, cardiopulmonary bypass was not used, and estimated blood loss was minimal. The patient was discharged on postoperative day 5, and at 3-month follow-up demonstrated significant clinical and hemodynamic improvement. Conclusions: The automated coring and apical connector insertion device facilitated the safe and effective performance of aortic valve bypass surgery. [ABSTRACT FROM AUTHOR]
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- 2012
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24. Paravertebral analgesia for cardiac surgery.
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Harle, Christopher C. and Ganapathy, Su
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PARAVERTEBRAL anesthesia ,POSTOPERATIVE care ,CARDIAC surgery ,CRITICAL care medicine - Abstract
High-quality analgesia following cardiac surgery is infrequently obtained. Pain management is seldom a priority in the immediate postoperative care of these patients, who frequently require mechanical ventilation in an intensive care environment. These patients may be physiologically unstable, and attention to hemostasis and cardiopulmonary stability is usually of more concern in the initial phases of their care. Nevertheless, there are several compelling physiological, psychological, and humanitarian reasons that good pain relief should be offered to these patients. The frequently misguided perception that cardiac surgery is not painful, and the valid concerns many have regarding the side effects of opioid analgesia as well as the potential risks of thoracic epidural analgesia contribute to “oligoanalgesia” in the patient recovering from cardiac surgery. The evolution of minimally invasive cardiac surgery and the increasing clinical complexity of cardiac patients are providing an impetus to explore safe and effective analgesic techniques in this clinical domain. The role of paravertebral blockade in cardiac surgery has not been extensively investigated. At best, the literature to date is in the form of isolated case reports and observational studies. As such, a meaningful review of this topic can offer little more than commentary and discussion. However, paravertebral blockade has an established role in postoperative analgesia in general, and it confers some theoretical advantages over both conventional thoracic epidural analgesia as well as parenteral opioid therapy for cardiac patients. [Copyright &y& Elsevier]
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- 2008
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25. Coagulation Assessment in Children With Diabetic Ketoacidosis
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Tran, Thai Hoa, Al-Harfi, Ibrahim, Harle, Christopher C., Kahr, Walter H. A., Morrison, Gavin C., and Kornecki, Alik
- Abstract
To assess potential hypercoagulability during diabetic ketoacidosis in children.
- Published
- 2013
- Full Text
- View/download PDF
26. Consumer Perspectives on Maternal and Infant Health Apps: Qualitative Content Analysis.
- Author
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Biviji, Rizwana, Williams, Karmen S, Vest, Joshua R, Dixon, Brian E, Cullen, Theresa, and Harle, Christopher A
- Subjects
HEALTH education ,MOBILE apps ,MEDICAL care ,FAMILIES ,RESEARCH funding - Abstract
Background: Despite the popularity of maternal and infant health mobile apps, ongoing consumer engagement and sustained app use remain barriers. Few studies have examined user experiences or perceived benefits of maternal and infant health app use from consumer perspectives.Objective: This study aims to assess users' self-reported experiences with maternal and infant health apps, perceived benefits, and general feedback by analyzing publicly available user reviews on two popular app stores-Apple App Store and Google Play Store.Methods: We conducted a qualitative assessment of publicly available user reviews (N=2422) sampled from 75 maternal and infant health apps designed to provide health education or decision-making support to pregnant women or parents and caregivers of infants. The reviews were coded and analyzed using a general inductive qualitative content analysis approach.Results: The three major themes included the following: app functionality, where users discussed app features and functions; technical aspects, where users talked about technology-based aspects of an app; and app content, where users specifically focused on the app content and the information it provides. The six minor themes included the following: patterns of use, where users highlighted the frequency and type of use; social support, where users talked about receiving social support from friends, family and community of other users; app cost, where users talked about the cost of an app within the context of being cost-effective or a potential waste of money; app comparisons, where users compared one app with others available in app stores; assistance in health care, where users specifically highlighted the role of an app in offering clinical assistance; and customer care support, where users specifically talked about their interaction with the app customer care support team.Conclusions: Users generally tend to value apps that are of low cost and preferably free, with high-quality content, superior features, enhanced technical aspects, and user-friendly interfaces. Users also find app developer responsiveness to be integral, as it offers them an opportunity to engage in the app development and delivery process. These findings may be beneficial for app developers in designing better apps, as no best practice guidelines currently exist for the app environment. [ABSTRACT FROM AUTHOR]- Published
- 2021
- Full Text
- View/download PDF
27. Infographic. International Olympic Committee consensus statement on pain management in athletes: non-pharmacological strategies
- Author
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Hainline, Brian, Derman, Wayne, Vernec, Alan, Budgett, Richard, Deie, Masataka, Dvorak, Jiri, Harle, Christopher A, Herring, Stanley, McNamee, Michael, Meeuwisse, Willem, Moseley, G Lorimer, Omololu, Bade, Orchard, John, Pipe, Andrew, Pluim, Babette M, Raeder, Johan, Siebert, David, Stewart, Mike, Stuart, Mark Campbell, Turner, Judith, Ware, Mark, Zideman, David, and Engebretsen, Lars
- Published
- 2019
- Full Text
- View/download PDF
28. First North American Experience With the Engager Self-Expanding Transcatheter Aortic Valve: Insights From the London Health Sciences Centre Heart Team.
- Author
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Bagur, Rodrigo, Kiaii, Bob, Teefy, Patrick J., Diamantouros, Pantelis, Lavi, Ronit, Harle, Christopher, Cassese, Mauro, and Chu, Michael W.A.
- Abstract
The Engager aortic bioprosthesis consists of bovine pericardial leaflets mounted on a self-expandable frame with unique anatomic orientation capabilities to engage the aortic valve cusps. We report the initial North American transcatheter aortic valve implantation (TAVI) experience with the Engager device. Transapical TAVI was performed in 4 patients (mean age 80 ± 6 years, Society of Thoracic Surgeons score 5 ± 1%). The valve was anatomically oriented and successfully implanted in all patients. There were no conversions to open operation or major procedure-related adverse events. Pacemaker implantation was necessary in 1 patient. None of the patients showed paravalvular leak. The Engager device for TAVI provides anatomic orientation and anchoring that prevents coronary obstruction and paravalvular leak. [ABSTRACT FROM AUTHOR]
- Published
- 2016
- Full Text
- View/download PDF
29. Transcatheter ACURATE-TA Aortic Valve Implantation in a Patient With a Previous Mechanical Mitral Valve.
- Author
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Bagur, Rodrigo, Kiaii, Bob, Teefy, Patrick J., Diamantouros, Pantelis, Harle, Christopher, Goela, Aashish, Chan, Ian, and Chu, Michael W.A.
- Abstract
Transcatheter aortic valve implantation (TAVI) in the presence of a mechanical mitral valve (MMV) prosthesis is still challenging because of the rigid mitral frame within the aortomitral curtain. Moreover, low-lying coronary ostia represent a hazardous problem of coronary obstruction, especially in narrow or porcelain aortic roots. The present case demonstrates the successful management of 2 challenging anatomical issues, the rigid cage of the MMV and the low-lying left main coronary ostium (LMCO), with the implantation of the ACURATE-TA bioprosthesis (Symetis SA, Ecublens, Switzerland). It also highlights the importance of having multiple TAVI devices in order to choose the ideal transcatheter aortic bioprosthesis to fit the unique anatomical presentation of the patient. [ABSTRACT FROM AUTHOR]
- Published
- 2015
- Full Text
- View/download PDF
30. The glidescope® cobalt videolaryngoscope — a novel single-use device
- Author
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Jones, Philip, Harle, Christopher, and Turkstra, Timothy
- Published
- 2007
- Full Text
- View/download PDF
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