72 results on '"HUGHES, LARRY"'
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2. Long-term reliability study and failure analysis of quantum cascade lasers
- Author
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Belyanin, Alexey A., Smowton, Peter M., Xie, Feng, Nguyen, Hong-Ky, Leblanc, Herve, Hughes, Larry, Wang, Jie, Miller, Dean J., and Lascola, Kevin
- Published
- 2017
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3. ANALYSIS OF JAVA-BASED END-TO-END WIRELESS INTERNET SECURITY.
- Author
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Hughes, Larry and Hay'awi, Abdul-Kadhim
- Subjects
INTERNET servers ,WIRELESS Internet ,WIRELESS Application Protocol (Computer network protocol) ,MOBILE apps ,AD hoc computer networks ,SECURITY systems - Abstract
The third and fourth generation wireless devices will require increasingly End-to-End (E2E) security solutions. Existing wireless security approaches has been studied comparatively. It is concluded that, Java 2 Micro Edition (J2ME) support for lightweight E2E security is a promising solution. The J2ME security features are analyzed from the perspective of its capability to provide efficient yet effective E2E security for the enterprise wireless applications. The analysis identifies particular design flaws. It also investigates open research problems associated with the current J2ME E2E security model. It is concluded that while there are still some problems with the deployment of Mobile Information Device Profile 2.0 (MIDP 2.0) of J2ME widely, its E2E security support is an important contribution to the wireless World Wide Web security. [ABSTRACT FROM AUTHOR]
- Published
- 2004
4. Faith and Sexual Orientation Identity Development in Gay College Men
- Author
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Dunn, Merrily, Glassmann, Danny, Garrett, J. Matthew, Badaszewski, Philip, Jones, Ginny, Pierre, Darren, Fresk, Kara, Young, Dallin, and Correll-Hughes, Larry
- Abstract
This study examines the experiences of gay-identified college men related to their faith and sexual orientation identity development. The findings suggest that for gay-identified college men, faith and sexual orientation identity development includes examination of one’s faith and sexual orientation identity, important relationships, and a desire for service and activism.
- Published
- 2015
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5. Future world oil production: growth, plateau, or peak?
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Hughes, Larry and Rudolph, Jacinda
- Abstract
With the exception of two oil shocks in the 1970s, world oil production experienced steady growth throughout the 20th century, from about 400,000 barrels a day in 1900 to over 74 million by 1999. Conservative projections from the International Energy Agency for 2035 suggest that production will increase to about 96 million barrels a day. If this target is met, world oil production will have exceeded 2000 gigabarrels (billion barrels) in the span of 135 years. Almost all of the oil products humans consume are derived from sources that are non-renewable. With this in mind, this paper considers how long world oil production can continue to grow or if it will eventually plateau or peak and then decline. The paper concludes with the observation that whether peak oil has already occurred or will not occur for many years, societies should be prepared for a world with less oil. [Copyright &y& Elsevier]
- Published
- 2011
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6. Mapping contaminant-transport structures in karst bedrock with ground-penetrating radar.
- Author
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Hughes, Larry J.
- Subjects
KARST ,BEDROCK ,GROUND penetrating radar ,AMMONIUM perchlorate ,PERCHLORATES ,TRENCHES - Abstract
Ammonium perchlorate, a risk to human health, was used formerly to manufacture rocket fuel at the Naval Weapons Industrial Reserve Plant (NWIRP) McGregor, McLennon County, Texas. Perchlorate exists in several groundwater contaminant plumes, whose geometries were suspected to be influenced by transmissive bedrock structures. To identify these possible contaminant-transport pathways, a towed-array ground-penetrating radar (GPR) system was used to acquire 118 line-km of data across 478 hectares of the property. The shallow geology consists of bedrock limestone overlain by 0 to 3 m of clay soil. For the 50-MHz antennas used, the conductive clay limits depth penetration to less than 3 m and yields a 1.4-m wavelength, reducing lateral and vertical resolution. Nevertheless, GPR data resolved the top of bedrock in many areas. Linear discontinuities in bedrock were interpreted as weathered fracture zones, and linear areas of signal loss were attributed to deeper clay weathering along fracture zones. GPR-interpreted fractures have orientations corresponding to known lineament and fault trends, appear to control plume geometries, and tend to have higher hydraulic transmissivities. GPR results led to a more complete contaminant- transport model and were used to optimize the positions of monitoring wells needed to define the extent of contamination. This reduced the cost and time required for an environmental investigation at the site. GPR was helpful also in positioning remedial trenches across contaminated structures, resulting in plume containment at the property boundaries. [ABSTRACT FROM AUTHOR]
- Published
- 2009
- Full Text
- View/download PDF
7. Overcoming an Environmental Surprise with Innovative, Fast-Track Technology
- Author
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Hughes, Larry, Epperson, Ann, and Williams, Tammy
- Abstract
As the Tennessee Department of Transportation (DOT) was finalizing the future route of I-69 through northwest Tennessee, a previously unknown, unregulated landfill was discovered directly beneath the proposed route near its juncture with a continuing segment into Kentucky. The Tennessee DOT, cooperating with the Tennessee Department of Environment and Conservation, implemented a rapid-response, technology-driven strategy to assess the potential costs and liabilities of crossing the landfill versus avoiding it. After a concerted site-history investigation, an electromagnetic geophysical survey mapped the landfill boundaries, established the area of fill, and identified areas of higher metal content within the fill. A concurrent soil–gas survey showed only isolated patterns of volatile organic compounds, often a driver for environmental mitigation costs. These results were used to optimize locations for subsurface drilling that employed the waste-minimizing sonic drilling technique. Depth of fill from exploratory drilling was combined with the geophysical delineation of landfill boundaries to yield an estimated waste volume of 65,000 m
3 (85,000 yd3 ) within the proposed I-69 footprint. Chemical analyses were done for subsurface sonic rig soil cores, surface soil samples, the contents of drums scattered across the surface, and surface water. These analyses showed relatively modest environmental risk; it was suggested that if the landfill were excavated, most of the soil could be handled as nontoxic special waste. Nevertheless, considering both design–build factors and environmental issues, the cost of excavating and building through the landfill ($33.5 million) exceeded that of rerouting slightly east of the landfill ($29.5 million), and the route was diverted to avoid the landfill.- Published
- 2013
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8. Acoustic Experience Alters the Aged Auditory System
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Turner, Jeremy G., Parrish, Jennifer L., Zuiderveld, Loren, Darr, Stacy, Hughes, Larry F., Caspary, Donald M., Idrezbegovic, Esma, and Canlon, Barbara
- Abstract
Presbyacusis, one of the most common ailments of the elderly, is often treated with hearing aids, which serve to reintroduce some or all of those sounds lost to peripheral hearing loss. However, little is known about the underlying changes to the ear and brain as a result of such experience with sound late in life. The present study attempts to model this process by rearing aged CBA mice in an augmented acoustic environment (AAE).
- Published
- 2013
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9. Overcoming an Environmental Surprise with Innovative, Fast-Track Technology: Case History Along I-69 Through Tennessee
- Author
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Hughes, Larry J., Epperson, Ann, and Williams, Tammy Keim
- Abstract
As the Tennessee Department of Transportation (DOT) was finalizing the future route of I-69 through northwest Tennessee, a previously unknown, unregulated landfill was discovered directly beneath the proposed route near its juncture with a continuing segment into Kentucky. The Tennessee DOT, cooperating with the Tennessee Department of Environment and Conservation, implemented a rapid-response, technology-driven strategy to assess the potential costs and liabilities of crossing the landfill versus avoiding it. After a concerted site-history investigation, an electromagnetic geophysical survey mapped the land-fill boundaries, established the area of fill, and identified areas of higher metal content within the fill. A concurrent soil–gas survey showed only isolated patterns of volatile organic compounds, often a driver for environmental mitigation costs. These results were used to optimize locations for subsurface drilling that employed the waste-minimizing sonic drilling technique. Depth of fill from exploratory drilling was combined with the geophysical delineation of landfill boundaries to yield an estimated waste volume of 65,000 m3(85,000 yd3) within the proposed I-69 footprint. Chemical analyses were done for subsurface sonic rig soil cores, surface soil samples, the contents of drums scattered across the surface, and surface water. These analyses showed relatively modest environmental risk; it was suggested that if the landfill were excavated, most of the soil could be handled as nontoxic special waste. Nevertheless, considering both design–build factors and environmental issues, the cost of excavating and building through the landfill ($33.5 million) exceeded that of rerouting slightly east of the landfill ($29.5 million), and the route was diverted to avoid the landfill.
- Published
- 2013
- Full Text
- View/download PDF
10. Business Practices in Higher Education: A Guide for Today's Administrators
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Correll-Hughes, Larry R.
- Abstract
Abstract
- Published
- 2012
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11. Business Practices in Higher Education: A Guide for Today's Administrators
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Correll-Hughes, Larry R.
- Published
- 2012
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12. Development of the Edmonson Psychiatric Fall Risk Assessment Tool
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Edmonson, Deborah, Robinson, Sherry, and Hughes, Larry
- Abstract
The purpose of this study was to develop a fall risk assessment instrument for the inpatient psychiatric population. Nine risk factors were identified through a review of the literature. The instrument was applied retrospectively to patient records, and the percentage of those who fell who triggered each of the items in each domain was calculated. The expected value of the population and weighting system were established. The Morse Fall Scale and Edmonson Psychiatric Fall Risk Assessment Tool (EPFRAT) were administered simultaneously to inpatient psychiatric patients. Sensitivity of the EPFRAT was 0.63, compared with 0.49 for the Morse Fall Scale; specificity of the EPFRAT was 0.86, compared with 0.85 for the Morse Fall Scale. Initial psychometric testing of the EPFRAT indicates the instrument is more sensitive in assessing fall risk in the acutely ill psychiatric population than those currently available. Additional psychometric testing is needed to determine the reliability and validity of the EPFRAT.
- Published
- 2011
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13. Early Prediction of Response to Chemoradiotherapy for Head and Neck Cancer: Reliability of Restaging With Combined Positron Emission Tomography and Computed TomographyPET-CT Restaging for Head and Neck Cancer
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Malone, James P., Gerberi, Michael A. T., Vasireddy, Syam, Hughes, Larry F., Rao, Krishna, Shevlin, Bruce, Kuhn, Matthew, Collette, Dean, Tennenhouse, Joel, and Robbins, K. Thomas
- Abstract
OBJECTIVE To assess the role of combined positron emission tomography and computed tomography (PET-CT) in predicting early treatment response at the primary site and in the neck after chemoradiotherapy (CRT) for advanced squamous cell carcinoma of the head and neck (SCCHN). DESIGN Retrospective analysis with a median follow-up of 24 months. SETTING Academic, tertiary referral center. PATIENTS AND INTERVENTIONS Thirty-one patients who were treated with concomitant intra-arterial CRT underwent PET-CT 6 to 8 weeks after the completion of treatment. Patients with findings on the physical examination, CT, or PET-CT indicative of persistent disease underwent appropriate surgical intervention for pathological assessment. Patients with a complete clinical response were observed with routine follow-up physical examination for disease recurrence. No evidence of disease at least 6 months after the completion of PET-CT was considered confirmation of complete clinical response. MAIN OUTCOME MEASURES Presence or absence of residual or recurrent disease during the follow-up period was used to calculate the sensitivity, specificity, and positive and negative predictive values of PET-CT for the primary site and the neck. RESULTS Assessment of tumor response at the primary site with PET-CT had a sensitivity, specificity, and positive and negative predictive values of 83%, 54%, 31%, and 92%, respectively. In patients with pretreatment N1 to N3 disease, the sensitivity, specificity, and positive and negative predictive values of posttreatment PET-CT were 75%, more than 94%, more than 75%, and 94%, respectively, and the specificity and negative predictive value for patients with pretreatment N0 disease in the neck were 92% and more than 92%, respectively. CONCLUSIONS Negative PET-CT findings accurately determine early disease response at the primary site and in the neck. False-positive findings are common at the primary site. Patients with a negative PET-CT finding after the completion of intra-arterial CRT do not require surgical intervention.Arch Otolaryngol Head Neck Surg. 2009;135(11):1119-1125--
- Published
- 2009
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14. Sleep during concanavalin-A-induced hepatitis and peritonitis in inbred mice.
- Author
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Toth, Linda A, Hughes, Larry F, and Rehg, Jerold E
- Abstract
To assess the suitability of concanavalin-A-induced hepatitis as a model for investigating the relationships between hepatic disease and alterations in somnolence.
- Published
- 2005
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15. The Effect of D-Methionine on Cochlear Oxidative State with and without Cisplatin Administration: Mechanisms of Otoprotection
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Campbell, Kathleen C.M., Meech, Robert P., Rybak, Leonard P., and Hughes, Larry F.
- Published
- 2003
- Full Text
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16. Antioxidant Enzyme Levels Inversely Covary with Hearing Loss After Amikacin Treatment
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Klemens, James J., Meech, Robert P., Hughes, Larry F., Somani, Satu, and Campbell, Kathleen C.M.
- Published
- 2003
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17. Audiologic Monitoring for Potential Ototoxicity in a Phase I Clinical Trial of a New Glycopeptide Antibiotic
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Campbell, Kathleen C.M., Kelly, Ellen, Targovnik, Nan, Hughes, Larry, Van Saders, Claudia, Gottlieb, Alice Bendix, Beth Dorr, Mary, and Leighton, Anton
- Published
- 2003
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18. Glutathione Ester But Not Glutathione Protects Against Cisplatin-Induced Ototoxicity in a Rat Model
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Campbell, Kathleen C.M., Larsen, Deb L., Meech, Robert P., Rybak, Leonard P., and Hughes, Larry F.
- Published
- 2003
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19. A Comparison of Electronystagmography Results with Posturography Findings from the BalanceTrak 500
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Amin, Manali, Girardi, Marian, Konrad, Horst R., and Hughes, Larry
- Abstract
To determine a correlation between conventional electronystagmography findings with results obtained from BalanceTrak 500 posturography assessment.
- Published
- 2002
20. Predicting Fall Risks in an Elderly Population: Computer Dynamic Posturography Versus Electronystagmography Test Results
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Girardi, Marian, Konrad, Horst R., Amin, Manali, and Hughes, Larry F.
- Abstract
Objectives/HypothesisFalls are the leading cause of morbidity and mortality for persons aged 65 years and older, with more than 2 million people falling and sustaining serious injury annually. This study compared computer dynamic posturography (CDP) and electronystagmography (ENG) results as predictors of falls.
- Published
- 2001
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21. Age‐related synaptic changes in the central nucleus of the inferior colliculus of Fischer‐344 rats
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Helfert, Robert H., Sommer, Teresa J., Meeks, Joshua, Hofstetter, Phillip, and Hughes, Larry F.
- Abstract
The central nucleus of the inferior colliculus (ICc) is a major processing center for the ascending auditory pathways. Gamma‐aminobutyric acid (GABA) and excitant amino acids (EAAs) are essential for coding many auditory tasks in the IC. Recently, a number of neurochemical and immunocytochemical studies have suggested an age‐related decline in GABAergic inhibition in the ICc, and possibly excitant‐amino‐acid‐mediated excitation as well. The objective of this study was to compare quantitatively changes in the synaptic organization of the ICc among three age groups (3, 19, and 28 months) of Fischer‐344 rats. Immunogold electron microscopic methods were used to determine if there were age‐related changes in the density, distribution, or morphology of GABA‐immunoreactive (+) and GABA‐immunonegative (–) synapses in the ICc. The data suggest similar losses of excitatory and inhibitory synapses in the ICc. There were significant reductions in the densities of GABA+ and GABA– synaptic terminals (∼30% and ∼24%, respectively) and synapses (∼33% and ∼26%, respectively) in the ICc of 28‐month‐old rats relative to 3‐month‐olds. The numeric values, which were adjusted to consider changes in volume of the IC with age, depict similar effects, although the effect magnitude for the adjusted values was reduced by approximately 9%. For both types of synapses, the decreases did not differ significantly from each other. The reductions in synaptic numbers appeared to be related to a similar numeric decline in dendrites, in particular those with calibers of between 0.5 and 1.5 μm. The number and distribution of synaptic terminals on the remaining dendrites of GABA– neurons appeared not to undergo major age‐related changes. GABA+ neurons, on the other hand, may have evolved patterns of synaptic and dendritic change during aging in which the distribution of synaptic terminals shifts to dendrites of larger caliber. In the 19‐month group, the synaptic areas were elevated in terminals apposed to dendrites with calibers of 1.5 μm or less. However, this increase in synaptic size did not persist in the aged animals. No neuronal losses were detectable among the three age groups. Thus, the decrease in GABA and EAAs identified in the IC by previous studies may be attributable to synaptic and dendritic declines, rather than cell loss. J. Comp. Neurol. 406:285–298, 1999. © 1999 Wiley‐Liss, Inc.
- Published
- 1999
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22. Essential Tremor Entrains Rapid Voluntary Movements
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Elble, Rodger J., Higgins, Constance, and Hughes, Larry
- Abstract
The effect of essential tremor on the timing of rapid wrist flexion was examined in 10 patients with moderate to severe disability. The mean reaction time and motor time of the patients did not differ from the mean values of 10 healthy age- and sex-matched controls. The latencies of the triphasic agonist and antagonist EMG bursts did not differ between patients and controls. The initiation of movement was time-locked to the tremor cycle in all patients. The initial agonist muscle activation occurred in phase with the rhythmic bursts of EMG, but the onset of rapid wrist flexion occurred when the momentum of essential tremor opposed the volitional movement. Essential tremor has subtle effects on motor control that transcend oscillation per se. These effects probably contribute to the impaired performance of fine motor tasks in patients with advanced disease.
- Published
- 1994
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23. Vestibular Deficits in Deaf Children
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Selz, Peter A., Girardi, Marian, Konrad, Horst R., and Hughes, Larry F.
- Abstract
Considerable knowledge has been accumulated regarding acquired and congenital deafness in children. However, despite the intimate relationship between the auditory and vestibular systems, data are limited regarding the status of the balance system in these children. Using a test population of 15 children, aged 8 to 17 years, we performed electronystagmography testing. The test battery consisted of the eye-tracking (gaze nystagmus, spontaneous nystagmus, saccade, horizontal pursuit and optokinetic) tests, positional/positioning (Dix-Hallpike and supine) tests, and rotational chair tests. With age-matched controls, five children were tested in each of the following three categories: normal hearing, hereditary deafness, and acquired deafness. The children in the hereditary deafness category were congenitally deaf and had a family history of deafness. Those subjects in the acquired deafness category had hearing loss before the age of 2 years, after meningitis. Analysis of variance demonstrated significant differences between the two deaf groups and the control subjects in the gaze nystagmus test, saccade latencies, horizontal pursuit phase, and Dix-Hallpike and supine positionally provoked nystagmus. Also, significant differences were found in rotational chair gain and phase between the deaf and normal-hearing children. The children with acquired deafness exhibited the most profound results. In addition, there were significant differences in rotational chair gain between the acquired and congenitally deaf children. No differences were noted in horizontal pursuit gains, saccade accuracies, or saccade asymmetries. These preliminary data demonstrate that the etiologic factors responsible for congenital and acquired deafness in children may indeed affect the balance system as well. These findings of possible balance disorders in conjunction with the profound hearing loss in this patient population will have prognostic implications in the future evaluation, treatment, and rehabilitation of these patients.
- Published
- 1996
- Full Text
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24. Age‐Related Glycine Receptor Subunit Changes in the Cochlear Nucleus of Fischer‐344 Rats
- Author
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Krenning, Judyann, Hughes, Larry F., Caspary, Donald M., and Helfert, Robert H.
- Abstract
Previous studies have shown that levels of binding for the strychnine‐sensitive glycine receptor in the cochlear nucleus (CN) of Fischer(F344) rats decrease with age. Given the major role glycine plays in normal CN function, changes in glycine‐receptor activity may contribute to central presbycusis. To further evaluate the impact of age on glycine receptors, in situ hybridization was used to assess, in three age groups of F344 rats, changes in levels of gene expression for four of its subunits. When compared with the 3‐month‐old rats, expression of mRNAs for α1and β subunits in the anteroventral CN decreased significantly in the 18‐ and 27‐month‐old age groups, while mRNA expression for the α2subunit increased. If protein expressions are similar, these subunit changes may alter the function of glycine receptors, thereby affecting binding to its ligands.
- Published
- 1998
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25. Vestibular Deficits in Deaf Children
- Author
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Selz, Peter A., Girardi, Marian, Konrad, Horst R., and Hughes, Larry F.
- Abstract
Considerable knowledge has been accumulated regarding acquired and congenital deafness in children. However, despite the intimate relationship between the auditory and vestibular systems, data are limited regarding the status of the balance system in these children. Using a test population of 15 children, aged 8 to 17 years, we performed electronystagmography testing. The test battery consisted of the eye-tracking (gaze nystagmus, spontaneous nystagmus, saccade, horizontal pursuit and optokinetic) tests, positional/positioning (Dix-Hallpike and supine) tests, and rotational chair tests. With age-matched controls, five children were tested in each of the following three categories: normal hearing, hereditary deafness, and acquired deafness. The children in the hereditary deafness category were congenitally deaf and had a family history of deafness. Those subjects in the acquired deafness category had hearing loss before the age of 2 years, after meningitis. Analysis of variance demonstrated significant differences between the two deaf groups and the control subjects in the gaze nystagmus test, saccade latencies, horizontal pursuit phase, and Dix-Hallpike and supine positionally provoked nystagmus. Also, significant differences were found in rotational chair gain and phase between the deaf and normal-hearing children. The children with acquired deafness exhibited the most profound results. In addition, there were significant differences in rotational chair gain between the acquired and congenitally deaf children. No differences were noted in horizontal pursuit gains, saccade accuracies, or saccade asymmetries. These preliminary data demonstrate that the etiologic factors responsible for congenital and acquired deafness in children may indeed affect the balance system as well. These findings of possible balance disorders in conjunction with the profound hearing loss in this patient population will have prognostic implications in the future evaluation, treatment, and rehabilitation of these patients.
- Published
- 1996
- Full Text
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26. Changes in Human Eighth Nerve Action Potential as a Function of Stimulation Rate
- Author
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Mouney, Daniel F., Berlin, Charles I., Cullen, John K., and Hughes, Larry F.
- Abstract
• The primary clinical utility of electrocochleography at the Louisiana State University Medical Center is the detection of hearing losses in children. This frequently requires the administration of a general anesthetic. Time required for this procedure could be shortened if stimuli were presented at a more rapid rate than the customary 10/s, provided the response amplitude is not significantly diminished by adaptation. The response amplitudes of 12 subjects were studied at stimulus rates of 10, 20, 40, and 80/s. An increase of response amplitude on the order of approximately 3:1 over the 10/s rate was found for the 80/s rate when the test interval for each was equal.(Arch Otolaryngol 104:551-554, 1978)
- Published
- 1978
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27. The syndrome of senile gait
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Elble, Rodger J., Hughes, Larry, and Higgins, Constance
- Abstract
Infrared computed stroboscopic photometry was used to quantify the kinematic profiles of walking in 10 elderly patients with symmetrical neurological disturbances of gait and in 19 age-matched neurologically healthy people. Clinical examination of the patients revealed similar profiles of walking even though their diagnoses were vascular dementia (2), normal pressure hydrocephalus (2), Alzheimer dementia with possible normal pressure hydrocephalus (2), mixed Alzheimer and vascular dementia (1), peripheral neuropathy (1), Alzheimer dementia with parkinsonian features (1), and un determined (1). Quantitatively, the patients' gait kinematics deviated greatly from control values, but these deviations were statistically attributable to reductions in stride. We suggest that many gait disturbances in elderly people are similar, regardless of etiology, because the characteristics of these gait disturbances are heavily veiled by nonspecific stride-dependent changes that comprise the syndrome of senile gait.
- Published
- 1992
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28. The internal mammary bypass graft: A superior second coronary artery
- Author
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Jones, James W., Ochsner, John L., Mills, Noel L., and Hughes, Larry
- Abstract
In a study of the initial 1,004 consecutive patients who had direct coronary artery bypass at Ochsner Medical Institutions, computer methods of data processing were used to compare the clinical results between patients who had saphenous vein (SV) grafts and those who had internal mammary artery (IMA) grafts. The factors compared were the long-term mortality rates, nonfatal myocardial infarction rates, relief or persistence of angina, and the percentage of patients who acquired congestive heart failure. A simple comparison showed the patients with IMA grafts did better in all four categories; however, in a subsequent analysis in which maldistributed factors were removed, the rates of anginal relief and congestive heart failure were not significantly improved. The major benefit appears to be an increase in longevity among patients who had IMA bypasses.
- Published
- 1978
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29. School-Based Management, Decentralization, and Citizen Control–A Perspective
- Author
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Hughes, Larry W.
- Abstract
School-based management and teacher-parent empowerment have both currency and emotional ring. The terms have become a kind of rallying cry. But each term lacks definition and bad things can happen when things only sound good.
- Published
- 1993
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30. Vestibular Deficits in Deaf Children
- Author
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Selz, Peter A., Girardi, Marian, Konrad, Horst R., and Hughes, Larry F.
- Abstract
Considerable knowledge has been accumulated regarding acquired and congenital deafness in children. However, despite the intimate relationship between the auditory and vestibular systems, data are limited regarding the status of the balance system in these children. Using a test population of 15 children, aged 8 to 17 years, we performed electronystagmography testing. The test battery consisted of the eye-tracking (gaze nystagmus, spontaneous nystagmus, saccade, horizontal pursuit and optokinetic) tests, positional/positioning (Dix-Hallpike and supine) tests, and rotational chair tests. With age-matched controls, five children were tested in each of the following three categories: normal hearing, hereditary deafness, and acquired deafness. The children in the hereditary deafness category were congenitally deaf and had a family history of deafness. Those subjects in the acquired deafness category had hearing loss before the age of 2 years, after meningitis. Analysis of variance demonstrated significant differences between the two deaf groups and the control subjects in the gaze nystagmus test, saccade latencies, horizontal pursuit phase, and Dix-Hallpike and supine positionally provoked nystagmus. Also, significant differences were found in rotational chair gain and phase between the deaf and normal-hearing children. The children with acquired deafness exhibited the most profound results. In addition, there were significant differences in rotational chair gain between the acquired and congenitally deaf children. No differences were noted in horizontal pursuit gains, saccade accuracies, or saccade asymmetries. These preliminary data demonstrate that the etiologic factors responsible for congenital and acquired deafness in children may indeed affect the balance system as well. These findings of possible balance disorders in conjunction with the profound hearing loss in this patient population will have prognostic implications in the future evaluation, treatment, and rehabilitation of these patients.
- Published
- 1996
- Full Text
- View/download PDF
31. Diuretic and diet effect on Menière's disease Evaluated by the 1985 Committee on Hearing and Equilibrium Guidelines
- Author
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Santos, Perry M., Hall, Raelene A., Snyder, Jack M., Hughes, Larry F., and Dobie, Robert A.
- Abstract
Fifty-four patients, diagnosed with Menière's disease and treated with diuretics and a low-salt diet, were evaluated retrospectively with the 1985 AAO/HNS Committee on Hearing and Equilibrium (CHE) guidelines for vertigo and hearing changes. The patient data base was also evaluated with other methods that helped determine the effectiveness of the 1985 AAO/HNS CHE guidelines. After 24 months of therapy, vertigo control was complete or substantial in 79% of the patients, limited or insignificant in 19%, and worse in 2% as evaluated by the CHE 1985 guidelines. Hearing improved in 35% of the patients, was unchanged in 29%, was worse in 22%, and could not be classified by CHE guidelines in 14%. Hearing was also evaluated by comparison of individual thresholds before medical therapy, and at 22 and 74 months after the start of medical therapy. We found a stabilization of low- and mid-threshold frequencies, with an average rate of hearing loss approximating 0 dB/yr with 74 months of followup. The results of this preliminary study suggest that diuretics and a low-salt diet may decrease the natural progression of sensorineural hearing loss in patients with Menière's disease. Compared with other methods of data analysis, the 1985 CHE guidelines lacked sensitivity to evaluate the hearing changes observed.
- Published
- 1993
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32. Event Handling in the Lego System
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HUGHES, LARRY
- Abstract
An event is an action that alters a programs normal flow of execution. Events can be classified into asynchronous (such as the expiration of a timer or a request to terminate a process) and synchronous (for example, arithmetic and protection faults). When an event occurs during the execution of a process, specialized software is required, either in the kernel, the process, or both. This paper describes the experiences gained in the design, implementation and operation of the event handling mechanism developed for the message-based Lego kernel and distributed system running on the iAPx86 platform. The resulting implementation is a uniform communication interface, treating all events as messages, thereby maintaining Legos send-receive paradigm. This implementation ensures that event messages follow processes that have migrated and permit the implementation of group event software. Several applications of the event handling software are presented, as is a discussion of the design tradeoffs. The paper concludes that although the basic concept of message-based event handling is well understood, a systems process naming technique can influence how events are handled in a migration and with process groups. © 1997 by John Wiley & Sons, Ltd.
- Published
- 1997
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33. Teaching Data Communications to Computer Science Students
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Hughes, Larry
- Abstract
Courses in data communications are becoming commonplace in many undergraduate computer science programs. The reason for this is abundantly clear: Data communications is pervading almost all aspects of computer science. However, to many students, data communications can be a difficult subject to master without having either prior experience in data communications or an electrical engineering background. In this article, the composition of a one-term course in data communications intended for computer science students without a background in either data communications or electrical engineering is presented. It includes a description of the course, its objectives, and assignments.
- Published
- 1990
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34. Vestibular deficits in deaf children
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SELZ, PETER A., GIRARDI, MARIAN, KONRAD, HORST R., and HUGHES, LARRY F.
- Abstract
Considerable knowledge has been accumulated regarding acquired and congenital deafness in children. However, despite the intimate relationship between the auditory and vestibular systems, data are limited regarding the status of the balance system in these children. Using a test population of 15 children, aged 8 to 17 years, we performed electronystagmography testing. The test battery consisted of the eye-tracking (gaze nystagmus, spontaneous nystagmus, saccade, horizontal pursuit and optokinetic) tests, positional/positioning (Dix-Hallpike and supine) tests, and rotational chair tests. With age-matched controls, five children were tested in each of the following three categories: normal hearing, hereditary deafness, and acquired deafness. The children in the hereditary deafness category were congenitally deaf and had a family history of deafness. Those subjects in the acquired deafness category had hearing loss before the age of 2 years, after meningitis. Analysis of variance demonstrated significant differences between the two deaf groups and the control subjects in the gaze nystagmus test, saccade latencies, horizontal pursuit phase, and Dix-Hallpike and supine positionally provoked nystagmus. Also, significant differences were found in rotational chair gain and phase between the deaf and normal-hearing children. The children with acquired deafness exhibited the most profound results. In addition, there were significant differences in rotational chair gain between the acquired and congenitally deaf children. No differences were noted in horizontal pursuit gains, saccade accuracies, or saccade asymmetries. These preliminary data demonstrate that the etiologic factors responsible for congenital and acquired deafness in children may indeed affect the balance system as well. These findings of possible balance disorders in conjunction with the profound hearing loss in this patient population will have prognostic implications in the future evaluation, treatment, and rehabilitation of these patients. (Otolaryngol Head Neck Surg 1996;115:70-7.)
- Published
- 1996
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35. Diuretic and diet effect on menière's disease evaluated by the 1985 committee on hearing and equilibrium guidelines
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Santos, Perry M., Hall, Raelene A., Snyder, Jack M., Hughes, Larry F., and Dobie, Robert A.
- Abstract
Fifty-four patients, diagnosed with Menière's disease and treated with diuretics and a low-salt diet, were evaluated retrospectively with the 1985 AAO/HNS Committee on Hearing and Equilibrium (CHE) guidelines for vertigo and hearing changes. The patient data base was also evaluated with other methods that helped determine the effectiveness of the 1985 AAO/HNS CHE guidelines. After 24 months of therapy, vertigo control was complete or substantial in 79% of the patients, limited or insignificant in 19%, and worse in 2% as evaluated by the CHE 1985 guidelines. Hearing improved in 35% of the patients, was unchanged in 29%, was worse in 22%, and could not be classified by CHE guidelines in 14%. Hearing was also evaluated by comparison of individual thresholds before medical therapy, and at 22 and 74 months after the start of medical therapy. We found a stabilization of low- and mid-threshold frequencies, with an average rate of hearing loss approximating 0 dB/yr with 74 months of followup. The results of this preliminary study suggest that diuretics and a low-salt diet may decrease the natural progression of sensorineural hearing loss in patients with Menière's disease. Compared with other methods of data analysis, the 1985 CHE guidelines lacked sensitivity to evaluate the hearing changes observed.
- Published
- 1993
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36. Clinical comparison between patients with saphenous vein and internal mammary artery as a coronary graft
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Jones, James W., Ochsner, John L., Mills, Noel L., and Hughes, Larry
- Abstract
From January, 1971, through May, 1978, the records of 1,239 patients who had comparable patterns of coronary artery bypasses were retrieved for study from the Ochsner computerized data bank. Seven hundred twenty-six patients had saphenous vein grafts (SVG) alone and 513 patients had internal mammary artery (IMA) grafts alone or in combination with SVG. Patients with IMA grafts had significantly improved survival over patients with SVGs, but after exclusion of biasing subgroups the improved survival was not reliably different (p = 0.1684). The percentages of patients who had unrelieved angina after operation were similar (5.0% versus 4.8%); the rates of nonfatal myocardial infarction and of postoperative congestive heart failure were also similar. When the recently done SVG bypasses were compared to those done before mid-1975, we found that unrelieved angina rates and nonfatal myocardial infarction rates were significantly improved in the recent group. We conclude that use of the SVG is indicated in some clinical situations and use of the IMA graft in others. Therefore, cardiovascular surgeons should be proficient in using both grafts.
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- 1980
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37. A Comparison of Short Forms of the Intelligence Scale for Children - Revised in the Screening of Gifted Referrals
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Killan, Janice B. and Hughes, Larry C.
- Abstract
A total of 142 full scale individual intelligence tests were rescored to compare the V and BD dyad of the WISC-R with the full scale WISC-R and the limen method of scoring of the S-B with the full scale S-B. Tests had been administered to students who had been referred for possible inclusion in a gifted program. The correlation ofthe limen short form andthe full scale S-B was. 78while the V and BD dyad and full scale WISC-R correlation was .92. Results suggest that the V and BD dyad of the WISC-R may be a useful screening device for superior students.
- Published
- 1978
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38. Olfactory Function in a Fertile Eunuch With Kallmann Syndrome
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Wortsman, Jacobo and Hughes, Larry F.
- Abstract
The olfactory and gonadal dysfunction in Kallmann syndrome share a common embryologic pathophysiology. To characterize further the linkage between the hypogonadotropic hypogonadism and anosmia, the authors performed a detailed evaluation of olfactory function in a patient with Kallmann Syndrome having the rare variant of partial gonadotropin deficiency (fertile eunuch). The subject was seen initially at age 16 years because of delayed puberty. He received testosterone replacement therapy and subsequently completed pubertal development. As an adult, while untreated, he had subnormal levels of serum testosterone, low gonadotropins, and normal response to luteinizing hormone-releasing hormone. He also had impotence that was reversible with testosterone therapy, and a normal sperm count. Despite the mild degree of hypogonadism, olfactory function was completely absent, and the response to nasal trigeminal stimulants was markedly attenuated. Complete anosmia may therefore be associated with gonadotropin deficiency that is only partial; the presence of anosmia does not predict the need for gonadotropin therapy to attain fertility.
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- 1996
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39. Temporal-Phonemic Processing Skills in Adult Stutterers and Nonstutterers
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Meyers, Susan C., Hughes, Larry F., and Schoeny, Zahrl G.
- Abstract
The purpose of this study was to investigate the hypothesis that stuttering is related to a dysfunction in auditory temporal processing. The performance of 20 adult male stutterers and 20 matched nonstutterers was studied using two auditory processing tasks. The subjects listened to stimuli with differential onset asynchronies during temporal order judgment (TOJ) and dichotic listening tasks. Stutterers and nonstutterers were not significantly different at judging which ear received the stimulation first (TOJ task) at varying stimulus onset asynchronies (SOAs). During the dichotic listening task, stutterers made significantly fewer double-correct responses (correct report for both stimuli in a dichotic pair) than nonstutterers. The stuttering subjects correctly classified one of the syllables in a pair (single-correct response) more frequently than normal controls on the dichotic listening task. These findings suggest that SOAs as a temporal parameter do not differentiate the performance of the two groups. The more difficult auditory processing task (dichotic identification) showed a significant difference in the performance of the stutterers versus nonstutterers.
- Published
- 1989
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40. Event Handling in the Lego System
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HUGHES, LARRY
- Abstract
An event is an action that alters a program's normal flow of execution. Events can be classified into asynchronous (such as the expiration of a timer or a request to terminate a process) and synchronous (for example, arithmetic and protection faults). When an event occurs during the execution of a process, specialized software is required, either in the kernel, the process, or both. This paper describes the experiences gained in the design, implementation and operation of the event handling mechanism developed for the message‐based Lego kernel and distributed system running on the iAPx86 platform. The resulting implementation is a uniform communication interface, treating all events as messages, thereby maintaining Lego's send‐receive paradigm. This implementation ensures that event messages follow processes that have migrated and permit the implementation of group event software. Several applications of the event handling software are presented, as is a discussion of the design tradeoffs. The paper concludes that although the basic concept of message‐based event handling is well understood, a system's process naming technique can influence how events are handled in a migration and with process groups. © 1997 by John Wiley & Sons, Ltd.
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- 1997
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41. The S-Machine: An Alternative Approach to Teaching Assembler Programming
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Hughes, Larry
- Abstract
The demand for assembler language programmers has dropped dramatically over the past 20 years with the advent of structured programming languages and the accessibility of hardware features from high-level languages. Nevertheless, a course in assembler language programming is often the first, and sometimes the only, introduction a student has to a machine's hardware. For this reason alone, assembler language programming courses should not be removed from a curriculum; instead, they should be kept and taught in conjunction with modern software engineering practices. This article describes an alternative approach to teaching assembler language programming. Whereas the students are still introduced to a machine and its assembler language, they are required to write several low-level library routines they used in introductory courses (such as ACM CS1 and CS2). Furthermore, the S-Machine's support software allows students to study the internals of an assembler, a librarian, and a linker.
- Published
- 1995
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42. Teaching Tools for CS1 and CS2
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Hughes, Larry
- Abstract
In most introductory computer science courses, students are expected to simultaneously learn a computer system (and its editor), a programming language, and how to develop algorithms (from which to write software). To many students, these are three distinctly alien activities, offering little to which they can relate. As with most new subjects, if students can establish a link between new material and their existing knowledge, the new material is more readily assimilated. This article describes a number of teaching tools that can be applied to the teaching of introductory computer science courses such as Computer Science 1 (CS1) and Computer Science 2 (CS2).
- Published
- 1995
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43. Chapter XIII: Frontiers of the Law
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Hughes, Larry W. and Gordon, William M.
- Published
- 1978
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44. The role of reinforcement and nonreinforcement in an operant frustration effect
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Hughes, Larry and Dachowski, Lawrence
- Abstract
Male albino rats were run in a discrete-trial two-bar operant analog of the double alley. Completion of a FR 4 response chain on the first bar was rewarded 50% of the time for the 12 experimental Ss, but was never rewarded for the 12 control Ss. Both groups received consistent reward at the end of a FR 4 chain on the second bar. Eighty-four trials were given at a rate of four trials per day. A significantly faster rate of responding on the second bar was found following nonrewarded first-bar ratios than following rewarded first-bar ratios. This frustration effect was not attributable to response depression, since the nonrewarded performance of the experimental group exceeded that of the control group.
- Published
- 1973
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45. An Evaluation Procedure for a New Program to Prepare Administrator Change Agents
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Hughes, Larry W. and Tanner, C. Kenneth
- Abstract
In this article the authors describe a new administrative preparation program which they conduct. They also discuss at some length a procedure developed for evaluating that program.
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- 1970
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46. "Organizational Climate"-Another Dimension to the Process of Innovation?
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Hughes, Larry W.
- Abstract
This article inquires into the process of innovation as it might relate to certain characteristics existent in the central offices of school districts. It results from a federally funded research inquiry made by the author. The author, who holds the Ph.D. degree from Ohio State University, is Associate Professor in the Department of Educational Administration at the University of Tennessee.
- Published
- 1968
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47. Simulation: It's the Real Thing
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Rasmussen, Gerald R. and Hughes, Larry W.
- Abstract
In response to the criticism that preparation programs for principals are bookish and out-of-date, the writer in this article examines simulation as an effective instructional tool.
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- 1972
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48. New Leadership for the Secondary School
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Hughes, Larry W. and Ubben, Gerald C.
- Abstract
The University of Tennessee for two years re ceived a grant from the U.S. Office of Education for a training program designed for entry level administrators. This article discusses the ra tionale around which the training program was designed.
- Published
- 1970
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49. Frustration Effect and Extent of Instrumental Response
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Dunlap, William P., Hughes, Larry F., and O'Brien, Thomas J.
- Abstract
Goal-box activity of Ss run in a single alley was compared to activity of Ss placed directly into the goal box. Following nonreward significant increases in activity above rewarded activity levels were found for both Run and Placed groups. When these effects were compared to goal-box activity levels of never-rewarded control groups, however, only the activity increments in the Run group could be attributed to frustration produced by nonreward. The results are discussed in terms of Amsel's (1958) theory.
- Published
- 1973
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50. Quantitative Assessment of Laryngeal Muscle Morphology After Recurrent Laryngeal Nerve Injury: Right vs. Left Differences
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Woodson, Gayle E., Hughes, Larry F., and Helfert, Robert
- Abstract
Objectives/Hypothesis:Reports of laryngeal response to denervation are inconsistent. Some document atrophy and fibrosis in denervated laryngeal muscles, whereas others indicate resistance to atrophy. Spontaneous reinnervation has also been documented. The goal of this study was to clarify the effects of nerve injury and reinnervation on thyroarytenoid (TA) and posterior cricoarytenoid (PCA) muscles.
- Published
- 2008
- Full Text
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