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2. Autoimmune pancreatitis and non-necrotizing acute pancreatitis: Computed tomography pattern.

Author

Graziani, Rossella, Frulloni, Luca, Mantovani, William, Ambrosetti, Maria Chiara, Mautone, Simona, Re, Thomas Joseph, Dal Bo, Chiara, Manfredi, Riccardo, and Mucelli, Roberto Pozzi

Subjects
AUTOIMMUNE diseases, NECROTIZING pancreatitis, TOMOGRAPHY, RETROSPECTIVE studies, QUALITATIVE research, PLEURAL effusions
Abstract

Abstract: Objectives: To retrospectively differentiate diffuse autoimmune pancreatitis from non-necrotizing acute pancreatitis at clinical onset with multi detector row computed tomography. Methods: 36 Patients suffering from diffuse autoimmune pancreatitis (14) or non-necrotizing acute pancreatitis (22) were enrolled. Qualitative analysis included stranding, retroperitoneal fluid film, capsule-like rim enhancement and pleural effusion. In quantitative analysis pancreatic density was measured in all phases. The vascularization behaviour was assessed using the relative enhancement rate across all phases. Results: Pancreatic density resulted lower in non-necrotizing acute pancreatitis compared to diffuse autoimmune pancreatitis patients in pre-contrast phase and higher in pancreatic phase. Relative enhancement rate evaluation confirmed different vascularization behaviours of the two diseases. Only non-necrotizing acute pancreatitis Patients presented peripancreatic stranding and fluid in the retromesenteric interfascial plane. Conclusions: Multi detector row computed tomography is a useful technique for differentiating diffuse autoimmune pancreatitis from non-necrotizing acute pancreatitis at clinical onset. Peripancreatic stranding and retroperitoneal fluid film, characteristic of non-necrotizing acute pancreatitis, and late-phase peripheral rim enhancement, characteristic of diffuse autoimmune pancreatitis, provide qualitative clues to the differentiation. A quantitative study of contrast enhancement patterns, considering the relative enhancement rate, can assist in the differential diagnoses of two diseases. [Copyright &y& Elsevier]

Published
2012
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3. Clinical and Radiological Outcome of Patients Suffering From Chronic Pancreatitis Associated With Gene Mutations

Author

Frulloni, Luca, Scattolini, Chiara, Graziani, Rossella, Cavestro, Giulia Martina, Pravadelli, Cecilia, Amodio, Antonio, Manfredi, Riccardo, Scarpa, Aldo, and Vantini, Italo

Abstract

Cystic fibrosis transmembrane conductance regulator (CFTR), cationic trypsinogen gene (PRSS1), and serine protease inhibitor kazal type 1 (SPINK1) gene mutations have been associated with chronic pancreatitis (CP). The aim of this study was to compare clinical and radiological findings in sporadic CP with (CPgm) and without (CPwt) gene mutations.

Published
2008
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4. Spontaneous rupture of a pancreatic pseudocyst into the portal vein

Author

Procacci, Carlo, Mansueto, Gian Carlo, Graziani, Rossella, Bicego, Egidio, Pederzoli, Paolo, Mainardi, Paride, Bergamo-Andreis, Ivo, Valdo, Moreno, and Azzolini, Diana

Abstract

Spontaneous rapture of a pancreatic pseudocyst into the portal vein is described. This has been previously reported in only five cases. Diagnosis was made by computed tomography (CT) and was confirmed by CT-guided transhepatic portography.

Published
1995
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5. Multiplanar study of the mediastinum with electronically reconstructed computed tomography images

Author

Procacci, Carlo, Andreis, Ivo A. Bergamo, Caudana, Roberto, Zonta, Loretta, Martini, Paolo Tinazzi, Graziani, Rossella, and Pistolesi, Gian Franco

Abstract

Refinements of computer software permit electronic reconstructions of CT sagittal, parasagittal, and coronal planes, which have markedly improved our understanding of the relations among mediastinal structures, most of which present a vertical course, as well as between focal lesions and adjoining structures.

Published
1987

6. Serous Cystadenoma of the Pancreas: Report of 30 Cases with Emphasis on the Imaging Findings

Author

Procacci, Carlo, Graziani, Rossella, Bicego, Egidio, Bergamo-Andreis, Ivo Andrea, Guarise, Alessandro, Valdo, Moreno, Bogina, Giuseppe, Solarino, Ugo, and Pistolesi, Gian Franco

Abstract

Our goal was to evaluate retrospectively 30 cases of serous cystadenoma (SCA) to determine its main imaging features as well as to discuss the differential diagnosis problems versus the other cystic lesions of the pancreas.

Published
1997

7. Surgical Treatment of Pancreatic Metastases from Renal Cell Carcinomas

Author

Butturini, Giovanni, Bassi, Claudio, Falconi, Massimo, Salvia, Roberto, Caldiron, Erminia, Iannucci, Antonio, Zamboni, Giuseppe, Graziani, Rossella, Procacci, Carlo, and Pederzoli, Paolo

Abstract

Pancreatic metastases from a renal cell carcinoma are rare and may occur long after manifestation of the primary disease. Resection of the metastases should be regarded as the best treatment. In our center, owing to the slow evolution of these secondaries, we perform resections capable of limiting the destruction of the pancreatic parenchyma as far as possible. The use of ‘atypical’ resections of the pancreas is characterized by a higher incidence of postoperative complications, particularly fistulas. Despite this, we believe that adjusted resection is to be advocated because of the possibility of additional remote secondaries, the shorter duration of surgery, the preservation of the glandular parenchyma and intact adjacent organs, such as duodenum, stomach, and spleen, and the fact that there have been no reports on local recurrences.

Published
1998
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8. Italian consensus guidelines for chronic pancreatitis.

Author

Frulloni, Luca, Falconi, Massimo, Gabbrielli, Armando, Gaia, Ezio, Graziani, Rossella, Pezzilli, Raffaele, Uomo, Generoso, Andriulli, Angelo, Balzano, Gianpaolo, Benini, Luigi, Calculli, Lucia, Campra, Donata, Capurso, Gabriele, Cavestro, Giulia Martina, De Angelis, Claudio, Ghezzo, Luigi, Manfredi, Riccardo, Malesci, Alberto, Mariani, Alberto, and Mutignani, Massimiliano

Subjects
PANCREATITIS treatment, DIABETES, DISEASE relapse, ENDOSCOPIC surgery, SURGICAL complications, HEALTH outcome assessment, MEDICAL radiography
Abstract

Abstract: This paper gives practical guidelines for diagnosis and treatment of chronic pancreatitis. Statements have been elaborated by working teams of experts, by searching for and analysing the literature, and submitted to a consensus process by using a Delphi modified procedure. The statements report recommendations on clinical and nutritional approach, assessment of pancreatic function, treatment of exocrine pancreatic failure and of secondary diabetes, treatment of pain and prevention of painful relapses. Moreover, the role of endoscopy in approaching pancreatic pain, pancreatic stones, duct narrowing and dilation, and complications was considered. Recommendations for most appropriate use of various imaging techniques and of ultrasound endoscopy are reported. Finally, a group of recommendations are addressed to the surgical treatment, with definition of right indications, timing, most appropriate procedures and techniques in different clinical conditions and targets, and clinical and functional outcomes following surgery. [Copyright &y& Elsevier]

Published
2010
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