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1. Sinusoidal Obstruction Syndrome/Veno-Occlusive Disease after Unmanipulated Haploidentical Hematopoietic Stem Cell Transplantation with Post-Transplantation Cyclophosphamide: A Study on Behalf of the Spanish Hematopoietic Stem Cell Transplantation and Cellular Therapy Group (GETH)

Author

Gómez-Centurión, I., Gallardo Morillo, A.I., Pérez Martínez, A., Cabrero Calvo, M., Chinea, A., González, L., Pedraza, A., Jiménez Lorenzo, M.J., Robles, M. Calbacho, Bailén, R., Cascón, M. J. Pascual, Cabero, A., Piñana Sánchez, J.L., Luna, A., Perera Alvarez, M., Rovira, M., Torrent Catarineu, A., Sánchez-Pina, J., and Kwon, M.

Abstract

•This study describes characteristics of patients with SOS/VOD after haplo-HSCT with PT-Cy.•Among the 797 haplo-HSCT recipients, 46 patients (5.77%) were diagnosed from SOS/VOD.•Most of the patients developed very severe SOS/VOD according to revised EBMT severity criteria.•Despite a promising SOS/VOD CR rate (65%), 100-day mortality remained high (43%).

Published
2024
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