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• COVID-19 related hospitalizations associated with cardiac arrhythmias showed significantly higher rates of in-hospital mortality. • COVID-19 with arrhythmias also showed worse clinical outcomes, including higher rates of acute kidney injury, acute heart failure, acute stroke, cardiogenic shock, cardiac arrest, major bleeding episode and endotracheal intubations during the hospitalization. • Resource utilization including length of hospital stay and total adjused cost of hospitalization was higher in COVID-19 patiens with arrhythmias. • These patients also had lower odds of receiving interventions such cardiac pacing, cardioversion or pacemaker insertion during the hospitalization. The risk of arrhythmia is high in patients with COVID-19. The current literature is limited in understanding the clinical impact of arrhythmias and the extent of healthcare utilization in COVID-19 patients. The Nationwide In-patient Sample Database (NIS) from 2019 to 2020 was queried to identify COVID-19 patients who developed arrhythmias vs those without. Multivariate regression for adjusted odds ratios (aOR) and propensity score matching (PSM) were done to compare outcomes among both cohorts. A total of 1,664,240 patients (weighted) were hospitalized with COVID-19 infection, 380,915 (22.89%) of whom were diagnosed with an arrhythmia. After propensity matching COVID-19 with arrhythmias had higher rates of in-hospital mortality (22.4% vs 13.5%, P < 0.001), acute kidney injury (PSM 39.4% vs 35.7%, P < 0.001), acute heart failure (AHF) (18.2% vs 12.6%, P < 0.001), acute stroke (0.76% vs 0.57%, P < 0.001), cardiogenic shock (1.38% vs 0.5%, P < 0.001), cardiac arrest (5.26% vs 2.3%, P < 0.001) acute myocardial infarction (AMI) (12.8% vs 7.8%, P < 0.001), intracerebral hemorrhage (0.63% vs 0.45%, P < 0.001), major bleeding (2.6% vs 1.8%, P < 0.001) and endotracheal intubation (17.04% vs 10.17% < 0.001) compared to arrhythmias without COVID-19. This cohort also had lower odds of receiving interventions such as cardiac pacing (aOR 0.15 95% Cl 0.13-0.189 P < 0.001), cardioversion (aOR 0.43 95% CI 0.40-0.46, P < 0.001), and defibrillator (aOR 0.087 95% Cl 0.061-0.124, P < 0.001) compared to arrhythmia patients without COVID-19. Cardiac arrhythmias associated with COVID-19 resulted in longer length of hospital stay and higher total costs of hospitalizations. Arrhythmias associated with COVID-19 had worse clinical outcomes with an increased rate of in-hospital mortality, longer length of hospital stay, and higher total cost. These patients also had lower odds of receiving interventions during the index hospitalization. [ABSTRACT FROM AUTHOR]

The ongoing research for tribonegative materials has resulted in significant progress in triboelectric nanogenerators (TENG), but the search for tribopositive materials is limited. Therefore, it is still a challenging task to achieve low cost, readily available, easy process for fabrication of tribomaterials with high positive triboelectric properties for triboelectric nanogenerators. Here we propose a novel method to synthesize high porous cryogel films based on facile freezing, ultraviolet radiation and thawing processes and used it as the tribopositive material for TENG fabrication while spin-coated polydimethylsiloxane (PDMS) is used as the tribonegative material. The cryogel/PDMS TENG device with a dimension of 1 × 2 cm2 showed an open circuit voltage of 170 V, and a short circuit current density of 17.1 mA/m2 and an instantaneous power density of 2.95 W/m2 which is able to light up 180 white LEDs directly. Thorough investigations divulged that the high output performance of TENG can be attributed to the porous structure of the cryogel films and the formation of high-density mechanoradicals associated with the porous structure, which was proved by using radical scavanger 2,2,6,6-tetramethyl-1-piperidinyloxy. This study provides a simple, cost-effective and easy way of preparing cryogel films as the tribopositive material for TENGs, which increases the portfolio of tribopositive materials used for triboelectric nanogenerator with prodigious prospects. Image 1 • A novel porous cryogel films based on facile freezing, UV radiation and thawing processes, has been proposed as the tribopositive material. • The output performance can be attributed to the porous structure and formation of mechanoradicals of Cr-3t18/PDMS TENGs. • The cryogel shows excellent thermal and mechanical stability. [ABSTRACT FROM AUTHOR]