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Healthcare workers are vulnerable to adverse mental health impacts of the COVID-19 pandemic. We assessed prevalence of mental disorders and associated factors during the first wave of the pandemic among healthcare professionals in Spain.

We aimed to study the liver iron concentration in patients referred for hyperferritinemia to six hospitals in the Basque Country and to determine if there were differences between patients with or without metabolic syndrome.

This article addresses whether or not determination of liver iron concentration by MRI is becoming the new gold standard for diagnosing iron overload in hereditary hemochromatosis and other liver iron-surcharge diseases. Hepatic iron concentration obtained by liver biopsy has been the gold standard for years. In recent years the development of MRI techniques, via signal intensity ratio methods or by relaxometry, has provided a noninvasive and more accurate approach to the diagnosis of liver iron overload. Nowadays, liver biopsy indications have diminished and only prognostic purposes or diagnostic difficulties may justify its indication. We comment on the difficulty that liver steatosis creates for liver iron determination, a paper on MR elastography for fibrosis prognosis in hemochromatosis, the relationship between iron-free nodules and hepatocarcinoma, and the importance of the MR machine's calibration for accurate liver iron concentration determinations. Finally, based on the available evidence, we conclude that MRI is the new gold standard for the diagnosis of hepatic iron overload, in hemochromatosis and other liver iron disorders.

INTRODUCTION: There is growing interest in the safety of oxygen therapy in emergency patients. A Cochrane review of oxygen versus air for patients with acute myocardial infarction (AMI) showed a potentially important, but statistically non-significant, increase in mortality (RR 3.03 (95% CI 0.93 to 9.83)) and concluded a definitive randomised controlled trial (RCT) was needed. OBJECTIVE: To explore the feasibility of conducting an RCT of oxygen versus air in AMI, by exploring the beliefs of UK professionals who treat patients with AMI about oxygen's benefits, and to establish a baseline of reported practice by asking about their use of oxygen. METHOD: A cross-sectional online survey of UK emergency department, cardiology and ambulance staff. RESULT: 524 responses were received. All specialities had over 100 respondents. 98.3% said they always or usually use oxygen. 80% reported having local guidelines that recommended the routine use of oxygen. 55% believed oxygen definitely or probably significantly reduces the risk of death, while only 1.3% reported that they thought ‘it may even increase the risk of death.’ There were only minor differences across specialities and grades. CONCLUSION: Widespread belief in the benefit of oxygen in AMI may make it difficult to persuade funders of the importance of this issue and health professionals to participate in enrolling patients into a trial in which oxygen would be withheld from half their patients.