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1. Fatal varicella associated with selective natural killer cell deficiency

Author

Etzioni, A., Eidenschenk, C., Katz, R., Beck, R., Casanova, J.L., and Pollack, S.

Abstract

A 2-year-old girl with recurrent severe varicella infections had a fatal outcome. Studies of cellular and humoral immunity were normal. No natural killer (NK) cells were detected, and NK activity was markedly decreased. The interleukin (IL)15/IL15R signaling pathway was intact. This case emphasizes the role of NK cells in controlling herpes viral infection.

Published
2005
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