19 results on '"Duchenne, J"'
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2. Actualités en médecine d’urgence
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Gloaguen, A., Cesareo, É., Alhanati, L., Lefort, H., Duchenne, J., Dahan, B., and Freund, Y.
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- 2017
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3. Actualités en médecine d’urgence
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Claret, P.-G., Moser, C., Duchenne, J., Dahan, B., Cesareo, E., and Freund, Y.
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- 2017
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4. Actualités en médecine d’urgence
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Claret, P.-G., Lefort, H., Zanker, C., Duchenne, J., Dahan, B., and Freund, Y.
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- 2016
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5. Premier niveau de compétence pour l’échographie clinique en médecine d’urgence. Recommandations de la Société française de médecine d’urgence par consensus formalisé
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Duchenne, J., Martinez, M., Rothmann, C., Claret, P., Desclefs, J., Vaux, J., Miroux, P., and Ganansia, O.
- Abstract
L’utilisation de l’échographie en médecine d’urgence est incontournable. La Société française de médecine d’urgence a pris l’initiative de l’élaboration de recommandations d’un premier niveau de compétence d’échographie clinique en médecine d’urgence (ECMU), dans son champ d’investigation et sur ses modalités d’enseignement et de maintien des compétences. Ces recommandations s’appliquent à la pratique de la médecine d’urgence dans ses différentes modalités d’exercice: intra‑ et extrahospitalière, médecine de catastrophe, médecine d’exception, milieu isolé ou périlleux. La méthodologie utilisée est issue de la méthode « Recommandations par consensus formalisé » publiée par la Haute Autorité de santé (HAS) et de la méthode Delphi pour quantifier l’accord professionnel. Ce choix a été fait devant l’insuffisance de littérature de fort niveau de preuve dans certaines thématiques et de l’existence de controverses. Ce document présente les items jugés appropriés par les cotateurs. Ces recommandations définissent un premier niveau de compétence en ECMU. The use of ultrasound in emergency medicine cannot be avoided. These guidelines have been developed by the French Society of Emergency Medicine (Société française de médecine d’urgence) for clinical skills in ultrasound first level in emergency medicine (échographie clinique en médecine d’urgence [ECMU]). This guideline covers emergency medicine field of investigation, teaching methods and skills maintenance. These guidelines can be applied to emergency medicine practice in its different modalities of exercise: in and out of hospital environment, disaster medicine, isolated or dangerous areas. The methodology is based on the “Recommendations by Formal Consensus” method published by the French National Authority for Health (HAS) and the Delphi method to quantify the professional agreement. The lack of high‑level evidence publications and the existence of controversy were the main reasons to choose this methodology. This document presents the items deemed appropriate by the raters. These guidelines define the first level of competence in ECMU.
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- 2016
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6. Actualités en médecine d’urgence
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Claret, P., Zanker, C., Duchenne, J., Rothmann, C., Dahan, B., Ganansia, O., Freund, Y., and Cheron, G.
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- 2016
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7. Actualités en médecine d’urgence
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Carpentier, F., Duchenne, J., Rothmann, C., Rerbal, D., and Dahan, B.
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- 2015
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8. Prise en charge de la fibrillation atriale en médecine d’urgence. Recommandations de la Société française de médecine d’urgence en partenariat avec la Société française de cardiologie
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Taboulet, P., Duchenne, J., Lefort, H., Zanker, C., Jabre, P., Davy, J., Heuzey, J., and Ganansia, O.
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- 2015
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9. Actualités en médecine d’urgence
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Carpentier, F., Desclefs, J.-P., Duchenne, J., Lefort, H., Segal, N., and Valdenaire, G.
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- 2015
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10. Better diastolic function in CRT candidates is associated with improved survival after CRT implantation.
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Galli, E., Smiseth, O.A., Aalen, J., Larsen, C.K., Sade, E.L., Hubert, A., Anilkumar, S., Sirnes, P.A., Penicka, M., Linde, C., Le Rolle, V., Hernandez, A., Leclercq, C., Duchenne, J., Voigt, J., and Donal, E.
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The relationship between diastolic dysfunction (DD) and outcome after CRT is debated. The purpose of this study was to evaluate the role of DD in predicting all-cause mortality in heart failure patients undergoing CRT. One-hundred ninety-three patients (age: 67 ± 11 years, QRS width: 167 ± 21 ms, LVEF 28 ± 8%) were included in this multicentre prospective study. Mitral filling pattern, mitral tissue Doppler velocity, tricuspid regurgitation velocity, and indexed left atrial volume were used to classify DD from grade I to III according to the 2016 recommendations of the American Society of Echocardiography/European Association of Cardiovascular Imaging. A reduction of LV end-systolic volume > 15% at 6-month follow-up (FU) identified CRT-responders and was observed in 132 (68%) patients. During a median 35 months FU, 29 (15%) patients died. Through multivariable analysis, coronary artery disease [HR 2.21 (1.00–4.89) P = 0.05], NYHA [HR 2.92 (1.45–5.87), P = 0.003] and grade I DD [HR 0.34 (0.13–0.89)] were shown to be independent predictors of prognosis (Table 1). Grade I DD was associated with a longer survival rate in both responders and non-responders (Fig. 1). Non-responders with grade II-III DD had the worse outcome [HR 12.5 (3.56–44.04), P < 0.0001] Better diastolic function at baseline is associated with improved survival after CRT implantation, independently of CRT-response. [ABSTRACT FROM AUTHOR]
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- 2021
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11. Importance of systematic right ventricular assessment in patients undergoing cardiac resynchronisation therapy: A machine-learning approach.
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Galli, E., Le Rolle, V., Smiseth, O.A., Aalen, J., Sade, E.L., Hernandez, A., Leclercq, C., Duchenne, J., Voigt, J.U., and Donal, E.
- Abstract
Patients undergoing cardiac resynchronisation therapy are heterogeneous. Therefore, the prediction of CRT-response and outcome is challenging. The aim of this study was to evaluate the relative impact of clinical, electrocardiographic, and echocardiographic variables on the left ventricular (LV) remodelling and prognosis of CRT-candidates by the application of machine-learning (ML) approaches. In total, 193 patients undergoing CRT (mean age 67 ± 11 years, QRS width: 167 ± 21 msec) were prospectively included in this multicentre study. We used a combination of the Boruta algorithm and random forest methods (RF) to identify features predicting both CRT-volumetric response and prognosis. The model performance was tested by the area under the receiver-operating curve (AUC). We also applied the K-medoid method to identify clusters of phenotipically-similar patients. From 28 clinical, electrocardiographic, and echocardiographic-derived variables, 16 features were predictive of CRT-response, and 11 features were predictive of prognosis. Among the predictors of CRT-response, 6 variables (38%) pertained to right ventricular (RV) size or function. The tricuspid annular plane systolic excursion was the main feature associated with prognosis. The selected features were associated with a very good prediction of both CRT-response (AUC: 0.81, 95% CI: 0.74–0.87) and outcome (AUC 0.84, 95% CI: 0.75–0.93) (Fig. 1 A–B). An unsupervised ML approach allowed the identifications of two phenogroups of patients who differed significantly in clinical parameters, biventricular size and RV function and had significantly different prognosis (log-rank P < 0.0001; HR: 4.7, 95% CI: 2.1–10.0, P < 0.001) (Table 1). ML can reliably identify clinical and echocardiographic features associated with CRT-response and prognosis. Our results underscore the value of the assessment of RV-size and function parameters for the risk stratification of CRT-candidates. [ABSTRACT FROM AUTHOR]
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- 2021
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12. Actualités en médecine d’urgence
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Duchenne, J., Segal, N., Rothmann, C., and Bal dit Sollier, J.
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- 2014
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13. Actualités en médecine d’urgence
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Claret, P., Duchenne, J., Rothmann, C., and Bal dit Sollier, J.
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- 2013
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14. HIT Moderated Poster session: imaging in everyday practice
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Duchenne, J, Turco, A, Claus, P, Vunckx, K, Pagourelias, E, Rega, F, Gheysens, O, Voigt, JU, Popara-Voica, AM, Croitoru, A, Alexandru, D, Geavlete, D O, Popescu, B A, Ginghina, C, Jurcut, R, Duchenne, J, Claus, P, Turco, A, Vunckx, K, Pagourelias, E, Haemers, P, Van Puyvelde, J, Gheysens, O, Rega, F, Voigt, JU, Aruta, P, Muraru, D, Janei, C, Haertel Miglioranza, M, Cavalli, G, Romeo, G, Peluso, D, Cucchini, U, Iliceto, S, Badano, L, Teo, HK, Kui, SL, Chai, SC, Leong, KT, Tong, KL, Onciul, S, Muraru, D, Miglioranza, MH, Cucchini, U, Dorobantu, M, Iliceto, S, Badano, LP, Miskowiec, D, Kupczynska, K, Uznanska-Loch, B, Kasprzak, JD, Kurpesa, M, Lipiec, P, Onciul, S, Muraru, D, Miglioranza, MH, Cucchini, U, Dorobantu, M, Iliceto, S, Badano, LP, Rumbinaite, E, Vaskelyte, JJ, Lapinskas, T, Karuzas, A, Zvirblyte, R, Viezelis, M, Jonauskiene, I, Gustiene, O, Slapikas, R, Abellard, JA, Trochu, JN, Gueffet, JP, Cueff, C, De Groote, P, Bauters, C, Millaire, A, Polge, AS, and Le Tourneau, T
- Abstract
Purpose: To investigate the relationship between two measures of regional myocardial workload (RMW): regional myocardial glucose metabolism, assessed by 18F-fluorodeoxyglucose (FDG) positron emission tomography (PET) and regional LV pressure-strain loop area. Both were evaluated in a chronic rapid pacing animal model of dilated cardiomyopathy (DCM) and LBBB-like mechanical dyssynchrony. Methods: Nine sheep were subjected to rapid RV pacing (180 bpm), developing LV dilatation and asymetric remodelling, with LBBB-like ventricular activation. After 8 weeks all animals underwent two FDG-PET scans: one under normal LV conduction (AAI pacing), another under LBBB-like activation (DDD pacing). Potential inhomogeneities in RMW represented by FDG-uptake, were then evaluated. Before the last PET scan, all animals were subjected to invasive pressure-volume and simultaneous echocardiographic circumferential strain (CS) analysis of the mid-ventricular segments. Segmental pressure-CS-loop area was then recorded as alternative measure of RMW and compared to PET results. Results: DDD and AAI pacing led to different, but reproducible patterns of inhomogeneous RMW distribution (Figure) with a significant decreased septal-to-lateral wall ratio of RMW in DDD mode compared to AAI, both in the FDG-uptake (0.87 ± 0.09 vs 1.05 ± 0.15, resp., p=0.005) and pressure-strain loops area (0.22 ± 0.18 vs 0.94 ± 0.23, resp., p=0.0001). A significant correlation was found between both measures (r=0.584, p=0.018). Conclusions: Our study indicates that RMW can be measured with both regional FDG-uptake and the area of regional pressure-strain loops. The influence of motion and partial volume on the reconstructed FDG-uptake in the asymmetrically remodelled hearts is currently being investigated.
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- 2015
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15. Erratum: Prise en charge de la fibrillation atriale en médecine d’urgence. Recommandations de la Société française de médecine d’urgence en partenariat avec la Société française de cardiologie
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Taboulet, P., Duchenne, J., Lefort, H., Zanker, C., Jabre, P., Davy, J., Le Heuzey, J., and Ganansia, O.
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- 2017
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16. Rapid Fire Abstract session: new insights in cardiomyopthies
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Mihalcea, D, Florescu, M, Vladareanu, AM, Mihaila, S, Vinereanu, D, Bergler-Klein, J, Spannbauer, A, Zlabinger, K, Macejovska, D, Maurer, G, Gyongyosi, M, Grogan, M, Scott, C, Lin, G, Klarich, K, Miller, W, Dispenzieri, A, Pagourelias, E, Mirea, OC, Duchenne, J, Vovas, G, Van Aelst, L, Claus, P, Van Cleemput, J, Delforge, M, Bogaert, J, Voigt, JU, Faber, L, Burghardt, A, Seggewiss, H, Van Buuren, F, Horstkotte, D, Ciampi, Q, Olivotto, I, Gardini, C, Monserrat, L, Peteiro, J, Lopes, L, Cotrim, C, Losi, MA, Lazzeroni, DE, Picano, E, Debonnaire, P, Joyce, E, Van Den Brink, OVW, Bax, JJ, Delgado, V, Ajmone Marsan, N, Saberniak, J, Leren, IS, Haland, TF, Hopp, E, Edvardsen, T, and Haugaa, KH
- Abstract
CHOP regimen is standard chemotherapy in patients with non-Hodgkin's lymphoma (NHL), but its use is limited by the risk of cardiotoxicity. Aim. To define new parameters, such as 4D echo (4DE) LV deformation or biomarkers, to diagnose early cardiac dysfunction and predict cardiotoxicity. Methods. 37 patients (13 men, 62 ± 12 years) with NHL, without cardiac disease, with EF>53%, scheduled to receive CHOP, were assessed at baseline, after the 2nd and 4th cycle. 4DE was used to assess EF and LV systolic deformation: longitudinal, radial, circumferential, area strain (LS, RS, CS, AS). Troponin I was measured. Cardiotoxicity was defined as a decrease of EF <53%, with >10% from the baseline. Results. After the 4th cycle of CHOP, 10 patients (27%) (group I) developed cardiotoxicity, while 27 patients (group II) didn't. There was a significant reduction of all LV systolic deformation parameters starting with the 2nd cycle, but group I had lower values than group II (Table). The reduction of the LS after the 2nd cycle was the best independent predictor for the decrease of EF after the 4th cycle (R2=0.44, p=0.0001); a decrease of LS with >30% after the 2nd cycle predicted the development of cardiotoxicity after the 4th cycle (sb 100%, sp 85%). Conclusion. Assessment of 4DE myocardial deformation parameters are able to detect early chemotherapy-induced cardiotoxicity and to predict further changes in the EF of patients with NHL.
4D deformation parameters CHOP Group I Group II p value (Anova) LS (-%) Baseline 22 ± 2 22 ± 2 0.0001 2nd cycle 10 ± 1 16 ± 2* 0.0001 4th cycle 8 ± 1* 12 ± 2* 0.0001 CS (-%) Baseline 21 ± 2* 21 ± 2* 0.0001 2nd cycle 15 ± 1* 17 ± 2* 0.05 4th cycle 12 ± 3* 15 ± 1* 0.0001 RS (%) Baseline 56 ± 5* 56 ± 5* 0.0001 2nd cycle 40 ± 5* 46 ± 6* 0.05 4th cycle 33 ± 6* 39 ± 6* 0.0001 AS(%) Baseline 35 ± 4* 36 ± 4* 0.0001 2nd cycle 22 ± 5 28 ± 4* 0.0001 4th cycle 17 ± 5* 23 ± 4 0.01 - Published
- 2015
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17. Rapid Fire Abstract session: assessment of systolic function: clinical perspectives and future directions
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Baron, T, Christersson, C, Hedin, EM, Johansson, K, Flachskampf, FA, Kosmala, W, Rojek, A, Przewlocka-Kosmala, M, Karolko, B, Mysiak, A, Marwick, TH, Sarvari, S I, Sitges, M, Sanz, M, Tolosana Viu, JM, Edvardsen, T, Stokke, TM, Mont, L, Bijnens, B, Garcia Martin, A, Moya-Mur, JL, Carbonell-San Roman, S-A, Rodriguez-Munoz, D, Garcia-Lledo, A, Jimenez-Nacher, JJ, Segura-De La Cal, T, Fernandez-Golfin, C, Zamorano-Gomez, JL, Dumitrescu, S I, Droc, I, Neagoe, G, Mocanu, I, Murgu, V, Savoiu, D, Crisan, I, Dragomir, D, Stamate, S C, Cristian, G, Galli, E, Fournet, M, Samset, E, Leclercq, C, Donal, E, Pagourelias, E, Vovas, G, Duchenne, J, Mirea, OC, Van Aelst, L, Claus, P, Delforge, M, Van Cleemput, J, Bogaert, J, Voigt, JU, Martinez Santos, P, Batlle Lopez, E, Vilacosta, I, De La Rosa Riestra, A, Sanchez Sauce, B, Jimenez Valtierra, J, Espana Barrio, E, Campuzano Ruiz, R, Alonso Bello, J, and Perez Gonzalez, F
- Abstract
Aims: To assess the frequency of left ventricular (LV) systolic function impairment using classical echocardiographic parameters and their changes over time in patients with acute myocardial infarction (MI) and initially normal left ventricular ejection fraction (LV-EF ≥52% in males or ≥54% in females). Methods: All 421 consecutive patients with MI included in the Relevance of Biomarkers for future risk of thromboembolic events in UnSelected post-myocardial infarction patients (REBUS) study underwent 2D- and Doppler echocardiography within 72 hours and at one year after admission. LV-EF,diastolic and systolic volumes (LVEDVi, LVESV), mitral annular plane systolic excursion (MAPSE) and global longitudinal strain (GLS) were measured and data on first 100 patients with preserved LV-EF were analyzed in this pilot study. Results: LV-EF remained preserved (LV-EF ≥52% in males or ≥54% in females) in 74.2% of the patients < 72 h after MI. Among these patients impaired GLS (absolute value < 20%) was observed in 96.0 % of patients and decreased MAPSE (<1.1cm (females), 1.3cm (males)) in 56.6 % of patients. LVEDVi and LVESVi remained within normal range in all the studied patients (≤61ml/m2 (females) or ≤74ml/m2 (males), and ≤24ml/m2 (females) or ≤ 31ml/m2 (males), respectively). During one-year follow up (in absolute numbers of delta mean ± SD) the GLS improved with 3.4 ± 3.0%, while LV-EF decreased with 5.0 ± 7.7%. Both LVEDVi and LVESVi increased with 11.7 ± 10.4 ml/m2 and 7.1 ± 6.4 ml/m2, respectively. P<0.001 for all the analyses. MAPSE remained unchanged during the follow up. Conclusion: In the majority of patients within 72 h after MI and preserved LV-EF, at least one marker of systolic function was impaired, with GLS being the most common one. During the one-year follow up GLS improved, while the traditional parameters such as EF, LVEDVi and LVESVi significantly deteriorated, although still remaining within the normal range.
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- 2015
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18. Poster session 6: Saturday 6 December 2014, 08:30-12:30 * Location: Poster area
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Goirigolzarri Artaza, J, Gallego Delgado, M, Jaimes Castellanos, CP, Cavero Gibanel, MA, Pastrana Ledesma, MA, Alonso Pulpon, LA, Gonzalez Mirelis, J, Al Ansi, R Z, Sokolovic, S, Cerin, G, Szychta, W, Popa, B A, Botezatu, D, Benea, D, Manganiello, S, Corlan, A, Jabour, A, Igual Munoz, B, Osaca Asensi, JOA, Andres La Huerta, AALH, Maceira Gonzalez, AMG, Estornell Erill, JEE, Cano Perez, OCP, Sancho-Tello, MJSTDC, Alonso Fernandez, PAF, Sepulveda Sanchez, PSS, Montero Argudo, AMA, Palombo, C, Morizzo, C, Baluci, M, Kozakova, M, Panajotu, A, Karady, J, Szeplaki, G, Horvath, T, Tarnoki, DL, Jermendy, AL, Geller, L, Merkely, B, Maurovich-Horvat, P, Group, MTA-SE "Lendület" Cardiovascular Imaging Research, Moustafa, S, Mookadam, F, Youssef, M, Zuhairy, H, Connelly, M, Prieur, T, Alvarez, N, Ashikhmin, Y, Drapkina, O, Boutsikou, M, Demerouti, E, Leontiadis, E, Petrou, E, Karatasakis, G, Kozakova, M, Morizzo, C, Bianchi, V, Marchi, B, Federico, G, Palombo, C, Chatzistamatiou, E, Moustakas, G, Memo, G, Konstantinidis, D, Mpampatzeva Vagena, I, Manakos, K, Traxanas, K, Vergi, N, Feretou, A, Kallikazaros, I, Goto, M, Uejima, T, Itatani, K, Pedrizzetti, G, Mada, RO, Daraban, AM, Duchenne, J, Voigt, JU, Chiu, D Y Y, Green, D, Johnstone, L, Sinha, S, Kalra, PA, Abidin, N, Group, Salford Vascular Research, Sikora-Frac, M, Zaborska, B, Maciejewski, P, Bednarz, B, Budaj, A, Nemes, A, Sasi, V, Gavaller, H, Kalapos, A, Domsik, P, Katona, A, Szucsborus, T, Ungi, T, Forster, T, Ungi, I, Pluchinotta, FR, Arcidiacono, C, Saracino, A, Carminati, M, Bussadori, C, Dahlslett, T, Karlsen, S, Grenne, B, Sjoli, B, Bendz, B, Skulstad, H, Smiseth, OA, Edvardsen, T, Brunvand, H, Vereckei, A, Szelenyi, ZS, Szenasi, G, Santoro, C, Galderisi, M, Niglio, T, Santoro, M, Stabile, E, Rapacciuolo, A, Spinelli, L, De Simone, G, Esposito, G, Trimarco, B, Hubert, S, Jacquier, A, Fromonot, J, Resseguier, C, Tessier, A, Guieu, R, Renard, S, Haentjiens, J, Lavoute, C, Habib, G, Menting, M E, Koopman, LP, Mcghie, JS, Rebel, B, Gnanam, D, Helbing, WA, Van Den Bosch, AE, Roos-Hesselink, JW, Shiino, K, Yamada, A, Sugimoto, K, Takada, K, Takakuwa, Y, Miyagi, M, Iwase, M, Ozaki, Y, Placido, R, Ramalho, A, Nobre E Menezes, M, Cortez-Dias, N, Goncalves, S, Guimaraes, T, Robalo Martins, S, Francisco, AR, Almeida, AG, Nunes Diogo, A, Hayashi, T, Itatani, K, Inuzuka, R, Shindo, T, Hirata, Y, Shimizu, N, Miyaji, K, Henri, C, Dulgheru, R, Magne, J, Kou, S, Davin, L, Nchimi, A, Oury, C, Pierard, L, Lancellotti, P, Kovalyova, O, Honchar, O, Tengku, WINDA, Ketaren, ANDRE, Mingo Santos, S, Monivas Palomero, V, Restrepo Cordoba, A, Rodriguez Gonzalez, E, Goirigolzarri Artaza, J, Sayago Silva, I, Garcia Lunar, I, Mitroi, C, Cavero Gibanel, M, Segovia Cubero, J, Ryu, SK, Park, JY, Kim, SH, Choi, JW, Goh, CW, Byun, YS, Choi, JH, Westholm, C, Johnson, J, Jernberg, T, Winter, R, Rio, P, Moura Branco, L, Galrinho, A, Pinto Teixeira, P, Viveiros Monteiro, A, Portugal, G, Pereira-Da-Silva, T, Afonso Nogueira, M, Abreu, J, Cruz Ferreira, R, Mazzone, A, Botto, N, Paradossi, U, Chabane, A, Francini, M, Cerone, E, Baroni, M, Maffei, S, Berti, S, Tatu-Chitoiu, G P, Deleanu, D, Macarie, C, Chioncel, O, Dorobantu, M, Udroiu, C, Calmac, L, Diaconeasa, A, Vintila, V, Vinereanu, D, investigators, RO-STEMI, Ghattas, A, Shantsila, E, Griffiths, H, Lip, GY, Galli, E, Guirette, Y, Daudin, M, Auffret, V, Mabo, P, Donal, E, Fabiani, I, Conte, L, Scatena, C, Barletta, V, Pratali, S, De Martino, A, Bortolotti, U, Naccarato, AG, Di Bello, V, Falanga, G, Alati, E, Di Giannuario, G, Zito, C, Cusma' Piccione, M, Carerj, S, Oreto, G, Dattilo, G, Alfieri, O, La Canna, G, Generati, G, Bandera, F, Pellegrino, M, Alfonzetti, E, Labate, V, Guazzi, M, Cho, EJ, Park, S-J, Lim, HJ, Yoon, HR, Chang, S-A, Lee, S-C, Park, SW, Cengiz, B, Sahin, S T, Yurdakul, S, Kahraman, S, Bozkurt, A, Aytekin, S, Borges, I P, Peixoto, ECS, Peixoto, RTS, Peixoto, RTS, Marcolla, VF, Venkateshvaran, A, Sola, S, Dash, P K, Thapa, P, Manouras, A, Winter, R, Brodin, LA, Govind, S C, Mizariene, V, Verseckaite, R, Bieseviciene, M, Karaliute, R, Jonkaitiene, R, Vaskelyte, J, Arzanauskiene, R, Janenaite, J, Jurkevicius, R, Rosner, S, Orban, M, Nadjiri, J, Lesevic, H, Hadamitzky, M, Sonne, C, Manganaro, R, Carerj, S, Cusma-Piccione, MC, Caprino, A, Boretti, I, Todaro, MC, Falanga, G, Oreto, L, D'angelo, MC, Zito, C, Le Tourneau, T, Cueff, C, Richardson, M, Hossein-Foucher, C, Fayad, G, Roussel, JC, Trochu, JN, Vincentelli, A, Obase, K, Weinert, L, Lang, R, Cavalli, G, Muraru, D, Miglioranza, MH, Addetia, K, Veronesi, F, Cucchini, U, Mihaila, S, Tadic, M, Lang, RM, Badano, L, Polizzi, V, Pino, PG, Luzi, G, Bellavia, D, Fiorilli, R, Chialastri, C, Madeo, A, Malouf, J, Buffa, V, Musumeci, F, Gripari, P, Tamborini, G, Bottari, V, Maffessanti, F, Carminati, C, Muratori, M, Vignati, C, Bartorelli, A, Alamanni, F, Pepi, M, Polymeros, S, Dimopoulos, A, Spargias, K, Karatasakis, G, Athanasopoulos, G, Pavlides, G, Dagres, N, Vavouranakis, E, 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- Abstract
Introduction: The increase of left auricular volume (LAV) is a robust cardiovascular event predictor. Despite that echochardiography is more often used, cardiac MRI is considered more accurate. Our objetives are to validate "fast" LAV measures by MRI vs the considered gold standard (GS) and to compare Echo and MRI in a wide spectrum of patients. Methods: In a non-selected popullation with MRI study previously realized, we measured LAV by biplane method (BPMR) and by area-length in 4 chamber view (ALMR) and compared them with biplane (BPe) and discs method (MDDe) in 4 chamber view in echo. To validate MRI measurements, we measured LAV in short axis slices (Simpson Method, SM) in a group of patients and considered it the GS. Results: 186 patients were included (mean age 51 ± 17 age; 123 male; 14 in AF) with clinical indication of cardiac MRI (Philips 1,5 T). In 24 patients SM was calculated. 29% of cardiac MRI were considered normal. Mean underlying pathologies were myocardiopathy (27%), Ischemic myocardiopathy (17%), myopericarditis (10%), prior to AF ablation (4%), valvular disease (6%) and miscellaneous (7%). Excellent correlation was obtained between "fast" MRI measurements and SM in MRI (SM vs BPMR interclass correlation coefficient ICC=0.965 and SM vs ALMR, ICC=0.958; P<0.05) with low interobserver variability (ICC=0.983 for SM; ICC=0.949 for BPMR; ICC=0.931 for ALMR). "Fast" measurements by MRI showed stadistical correlation between them (CCI=0.910) (Figure). Correlation between Echo and MRI measures was only moderate. (BPRM vs BPe CCI=0,469 mean difference -30 ml; ALMR vs MDDe ICC=0,456 mean difference -24 mL). Conclusions: ‘fast’ LAV measures by MRI are comparable with the MRI GS and also between them. Echo values seem to underestimate compared to MRI, so its use may not be suitable.
- Published
- 2014
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19. Poster session 5: Friday 5 December 2014, 14:00-18:00 * Location: Poster area
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- Abstract
Clinical PET acquisitions of the heart suffer from artefacts and drops in image quality due to the poor spatial resolution of the PET system. Moreover, cardiac PET images are further degraded by the blur caused by the breathing and beating motions, thus hampering diagnosis and evaluation of myocardial pathologies. Anatomy-enhanced PET reconstruction, using a high-resolution CT, has proven useful in brain imaging. In cardiac datasets however, due to the motion artefacts, the application of any restoring technique on datasets affected by motion blur needs to be preceded by the validation of the proposed method on realistic static datasets. In this work, the validation is performed using static cardiac ex vivo datasets obtained from a number of sacrificed sheep, scanned on a clinical PET/CT scanner. The aim of this work is to assess the effectiveness of reconstructions of the acquired datasets with different CT-based anatomical priors, in comparison to reconstructions currently applied in clinical practise. The gold standard to which all reconstructions are compared consists of images of the same hearts scanned on a small-animal PET scanner, whose high spatial resolution allows for almost artefact-free images. Encouraging results were obtained so far, with improvements in volume delineation and uniformity of activity values when anatomical information was used. Fig 1 shows the gold standard image (left) compared to a regular clinical reconstruction (middle) and to a reconstruction using the high-resolution CT as anatomical information (right).
Figure - Published
- 2014
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