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Abstract: In this study, the gravity differential pressure fluctuation signal of Gas-liquid two-phase flow in horizontal pipeline was researched, it had no effect on the on-way resistance, and directly related to phase holdup of two-phase flow, and could reflect the variation of interphases force. The characteristic parameters of differential pressure signals were extracted by wave analysis, which was sensitive to the conversion from stratified flow to annular flow, so it proved a new way to flow pattern identification for gas-liquid two-phase flow and provided a strong evidence to reveal the flow pattern transition mechanism of gas-liquid two phase flow. [Copyright &y& Elsevier]