50 results on '"Carolina Pereira"'
Search Results
2. Applicability of terahertz spectroscopy in dentistry: a scoping review.
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Da Silva, Carolina Pereira, Costa, Rayanna Thayse Florêncio, Pereira, Arthur Césare Messias Viana, Gomes, Jéssica Marcela de Luna, Gomes, Anderson Stevens Leônidas, Moraes, Sandra Lúcia Dantas, and Lopes, Daniela Siqueira
- Abstract
This study aimed to analyze the scope, nature, and extent of the applicability of terahertz (THz) spectroscopy in dentistry. A scoping review was conducted following the 5-step methodology of Arksey and O'Malley, the PRISMA-ScR checklist, and the Evidence Synthesis Manual of the Joanna Briggs Institute. Electronic literature searches were performed in the PubMed/MEDLINE, Scopus, and Cochrane Library databases, including full-text articles with no specific publication period. The following research question was formulated: "What are the applications of THz spectroscopy in the field of dentistry?" Seventeen laboratory studies were identified, detailing oral and dental applications of THz. In restorative dentistry, 8 investigations sought to identify the properties of human and animal dental tissues and differentiate between healthy and decayed tissue. In oral pathology, 5 articles analyzed the identification of cancer cells in comparison to the identification of these cells in histological or cytological analysis. In biomaterials, 4 papers studied the changes in properties of restorative materials and effects on polymerization. While the potential for early diagnosis using THz spectroscopy in dentistry is evident, our findings underscore its limitations. The studies were exclusively conducted in vitro, emphasizing the need for innovative clinical research using intraoral devices. Bridging this gap is essential to unlock the full potential of this noninvasive technology for early diagnosis and informed clinical decision-making. [ABSTRACT FROM AUTHOR]
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- 2024
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3. Cost-effectiveness of Neonatal Hearing Screening Programs: Systematic Review
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Vernier, Luíza Silva, Fernandes, Carolina Pereira, Skorin, Pedro Pablo, Ávila, Audrei Thayse Viegel de, and Levandowski, Daniela Centenaro
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- 2024
- Full Text
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4. Sustainable production of xylose ester biosurfactant: a techno-economic-environmental analysis
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Cansian, Ana Bárbara Moulin, Gonçalves, Maria Carolina Pereira, Elias, Andrew Milli, Furlan, Felipe Fernando, Tardioli, Paulo Waldir, and de Sousa Júnior, Ruy
- Abstract
The search for alternatives that make the concept of a sustainable future conceivable and the possibility of having industries with low impact on global warming is among the most significant challenges today. The enzymatic production and application of xylose esters fit into this scenario as a potential sustainable biosurfactant with low environmental impact. Although several authors describe different possible operating conditions for the enzymatic production of xylose esters, studies that carry out techno-economic-environmental analysis (TEEA) for biosurfactant production are rare, and those that specifically apply TEEA for xylose esters production are even scarcer. In this context, this work aims to contribute to the development and scaling of the xylose ester production process by providing a TEEA of the biosurfactant production through enzymatic route using xylose and oleic acid as reagents. Phenomenological models were used to describe the process through mass and energy balances. The proposed process was simulated using EMSO, an equation-oriented simulator, from the esterification reaction to the downstream step, obtaining a biosurfactant with 96% purity. An economic analysis was also performed, which covered the installation and operating costs for a plant working throughout 25 years, obtaining a minimum biosurfactant selling price of US$ 392.98 per kg of biosurfactant produced. The process production cost obtained is justified by high biosurfactant purity and applicability in the pharmaceutical and cosmetic industries. In the life cycle assessment, the product showed low levels of ozone layer depletion (9.70×10-7kg CFC-11 eq/ kg), human toxicity (16.8kg 1,4-DB eq/ kg), aquatic marine ecotoxicity (1.06×104kg 1,4-DB eq/ kg), photochemical oxidation (3.96×10-2kg C2H4eq/ kg), acidification (1.07×10-1kg SO2eq/ kg), and eutrophication (5.44×10-2kg PO4eq/ kg), highlighting its environmental viability and lower impact.
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- 2024
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5. Unveiling the reproduction of Proteopsis argentea(Asteraceae): how the complex pollination system might influence its conservation status
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Borges, João Paulo Raimundo, Ferreira, Ilmara Aparecida Oliveira, Silva, Danubia Natalina, Novaes, Cinthia Soares, Machado, Ana Carolina Pereira, Baronio, Gudryan Jackson, Jorge, Leonardo Ré, and Rech, André Rodrigo
- Abstract
The reproductive success of organisms depends on the positive and negative interactions it establishes throughout its lifetime. Pollinators and mutualists increase adaptive value, while herbivory and antagonism impair plant performance. Asteraceae flowers, simultaneously interacting with pollinators, herbivores and parasitoids with the same structure (the flower head), serve as a model for studying these interactions. In this work we describe the multi-layered interactions between Proteopsis argentea,, its pollinators, endophagous herbivores and parasitoids, aiming to understand how they influence the plant's reproductive success and whether these processes are associated with its conservation status as vulnerable. We found that P. argenteaproduces little, but highly energetic nectar, acting in interactions with bees, hummingbirds and lepidopterans in a generalist pollination system. Antagonistic interactions were much less diverse, dominated by Xanthaciuraaff. chrysura. In addition, two morphospecies of parasitoid wasps used the flower heads of P. argentea, and may have a negative impact on antagonists. We also found that P. argenteapresents a reproductive insurance strategy, via autogamy, producing seeds without pollinators. The flowers of P. argenteaseem to act as efficient filters, promoting interactions with potential pollinators and parasitoids and limiting interaction with endophagous herbivores. The reproductive strategies of P. argentea, with an apparently efficient floral filter and reproductive insurance in the absence of pollinators, seems to indicate that reproduction is not a limiting factor for the species. Thus, for its conversation, measures ensuring the protection of its occurrence area should be prioritized.
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- 2024
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6. Economic burden of respiratory syncytial and parainfluenza viruses in children of upper-middle-income countries: a systematic review
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Rocha-Filho, César Ramos, Ramalho, Gabriel Sodré, Martins, Johnny Wallef Leite, Lucchetta, Rosa Camila, Pinto, Ana Carolina Pereira Nunes, da Rocha, Aline Pereira, Trevisani, Giulia Fernandes Moça, Reis, Felipe Sebastião de Assis, Ferla, Laura Jantsch, Mastroianni, Patrícia de Carvalho, Correa, Luci, Saconato, Humberto, and Trevisani, Virgínia Fernandes Moça
- Abstract
To identify and assess the current evidence available about the costs of managing hospitalized pediatric patients diagnosed with Respiratory Syncytial Virus (RSV) and Parainfluenza Virus Type 3 (PIV3) in upper-middle-income countries.
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- 2023
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7. Practical MRI of Endometrial Neoplasms, Part 3: Staging Pitfalls and Mimics
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Piccolo, Luciana Maksoud, Uski, Ana Claudia Vincenzi Raduan, de Ávila Fernandes, Jose, Abud, Carolina Pereira, Leite, Marcela Cavichioli, de Andrade Larre, Ailma Fabiane, and Naves Inácio Pedroso, Maria Helena
- Abstract
Endometrial carcinomas (ECs) exhibit well-recognized characteristics on MRI sequences. In T2-weighted imaging (T2WI), the tumor presents as a diffuse or well-delineated soft tissue mass with an epicenter in the endometrial cavity and a heterogeneous intermediate signal relative to the hyperintense normal endometrium and hypointense myometrium. In diffusion-weighted imaging (DWI), tumors are hyperintense at a high b value in correspondence with the hypointense signal in the apparent diffusion coefficient (ADC) map. In dynamic contrast-enhanced MRI (DCE-MRI), endometrial tumors can show slower enhancement than the myometrium in the early phases and a hypointense signal in the later phases. In summary, dynamic sequences assist in the evaluation of continuous enhancement of the subendometrial zone (best evaluated approximately 35–40 seconds after the injection of gadolinium) and the estimated degree of myometrial invasion (best evaluated during the equilibrium phase—2.5 minutes after the injection of the contrast) and permit an adequate evaluation of the presence of infiltration of the cervical stroma (CSI), ideally evaluated 4 to 5 minutes after the injection of the contrast.1
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- 2022
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8. Practical MRI of Endometrial Neoplasms, Part 2: MRI and FIGO Staging
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Piccolo, Luciana Maksoud, Uski, Ana Claudia Vincenzi Raduan, de Ávila Fernandes, Jose, Abud, Carolina Pereira, Leite, Marcela Cavichioli, de Andrade Larre, Ailma Fabiane, and Naves Inácio Pedroso, Maria Helena
- Abstract
MRI is the method of choice for the evaluation of endometrial carcinomas (ECs), from detection to evaluation of recurrent disease. Although the staging of ECs is done surgically using the system of the International Federation of Gynecology and Obstetrics (FIGO), preoperative assessment based on MRI findings helps in risk stratification and decision-making. The main parameters evaluated include the degree and depth of myometrial invasion, parametrial extent, and cervical stromal infiltration. The combination of T2-weighted imaging, dynamic contrast-enhanced MRI, and diffusion-weighted imaging increases the accuracy of EC diagnosis and staging. A proposed step-by-step guide was developed to help the radiologist formulate hypotheses and guide clinical reasoning from the approach of the patient to the preparation of the final report. A structured report is also proposed with the objective of improving report quality and facilitating communication with the treating physicians.
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- 2022
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9. Practical MRI of Endometrial Neoplasms, Part 1: Background and Imaging Protocols
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Piccolo, Luciana Maksoud, Uski, Ana Claudia Vincenzi Raduan, de Ávila Fernandes, Jose, Abud, Carolina Pereira, Leite, Marcela Cavichioli, de Andrade Larre, Ailma Fabiane, and Naves Inácio Pedroso, Maria Helena
- Abstract
MRI is the method of choice for the evaluation of endometrial carcinomas (ECs), from detection to evaluation of recurrent disease. Although the staging of ECs is done surgically using the system of the International Federation of Gynecology and Obstetrics (FIGO), preoperative assessment based on imaging findings helps in risk stratification and decision-making. The main parameters evaluated include the degree and depth of myometrial invasion, parametrial extent, and cervical stromal infiltration. The combination of T2-weighted imaging, dynamic contrast-enhanced MRI, and diffusion-weighted imaging increases the accuracy of EC diagnosis and staging.
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- 2022
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10. Telerehabilitation improves physical function and reduces dyspnoea in people with COVID-19 and post-COVID-19 conditions: a systematic review.
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Vieira, Aléxia Gabriela da Silva, Pinto, Ana Carolina Pereira Nunes, Garcia, Bianca Maria Schneider Pereira, Eid, Raquel Afonso Caserta, Mól, Caroline Gomes, and Nawa, Ricardo Kenji
- Subjects
TELEREHABILITATION ,COVID-19 ,CONFIDENCE intervals ,POST-acute COVID-19 syndrome ,BREATHING exercises ,FUNCTIONAL status ,SYSTEMATIC reviews ,PATIENT satisfaction ,PATIENT readmissions ,TREATMENT effectiveness ,DYSPNEA ,BODY movement ,QUALITY of life ,DESCRIPTIVE statistics ,PATIENT compliance ,EVALUATION - Abstract
How effective and safe is telerehabilitation for people with COVID-19 and post-COVID-19 conditions? Systematic review of randomised trials. People with COVID-19 and post-COVID-19 conditions. Any type of telerehabilitation. Satisfaction, quality of life, adverse events, adherence to telerehabilitation, dyspnoea, functional performance, readmissions, mortality, pulmonary function and level of independence. Database searches retrieved 2,962 records, of which six trials with 323 participants were included in the review. Breathing exercises delivered via telerehabilitation improved 6-minute walk distance (MD 101 m, 95% CI 61 to 141; two studies), 30-second sit-to-stand test performance (MD 2.2 repetitions, 95% CI 1.5 to 2.8; two studies), Multidimensional Dyspnoea-12 questionnaire scores (MD –6, 95% CI –7 to –5; two studies) and perceived effort on the 0-to-10 Borg scale (MD –2.8, 95% CI –3.3 to –2.3; two studies), with low certainty of evidence. Exercise delivered via telerehabilitation improved 6-minute walk distance (MD 62 m, 95% CI 42 to 82, four studies), 30-second sit-to-stand test performance (MD 2.0 repetitions, 95% CI 1.3 to 2.7; two studies) and Multidimensional Dyspnoea-12 scores (MD –1.8, 95% CI –2.5 to –1.1; one study), with low certainty of evidence. Adverse events were almost all mild or moderate and occurred with similar frequency in the telerehabilitation group (median 0 per participant, IQR 0 to 2.75) as in the control group (median 0 per participant, IQR 0 to 2); Hodges-Lehmann median difference 0 (95% CI 0 to 0), with low certainty of evidence. Telerehabilitation may improve functional capacity, dyspnoea, performance and physical components of quality of life and does not substantially increase adverse events. PROSPERO CRD42021271049. [ABSTRACT FROM AUTHOR]
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- 2022
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11. Revised phylogenetic position of Nephrocytium Nägeli (Sphaeropleales, Chlorophyceae), with the description of Nephrocytiaceae fam. nov. and Nephrocytium vieirae sp. nov.
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da Silva, Thaís Garcia, Štenclová, Lenka, Archanjo, Naiara Carolina Pereira, and Bagatini, Inessa Lacativa
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ELECTRON microscopy ,MICROSCOPY ,RECOMBINANT DNA ,TUFAS - Abstract
The common planktonic green algal genus Nephrocytium was traditionally assumed to have a close relationship with the genus Oocystis and accordingly has been included in the family Oocystaceae. Although the position of Nephrocytium within the Oocystaceae has differed according to some authors over the years, its inclusion in the family has not been questioned. Following molecular studies of Oocystis, the Oocystaceae (including Nephrocytium) was removed from the class Chlorophyceae and placed in the Trebouxiophyceae. However, recent molecular studies of some of the former Oocystaceae members have returned them to the Chlorophyceae. These studies suggested the placement of Nephrocytium in the Sphaeropleales, but no taxonomic positioning within the order has been determined for the genus. The relocation of Nephrocytium agrees with a strong morphological trait – it lacks the oocystaceaean multilayered ultrastructure of the cell wall. Based on molecular markers (18S rDNA and tufA), and optical and electron microscopy, the present study aimed to establish the relationships of the genus within the Sphaeropleales. The results support the recognition of a new family, the Nephrocytiaceae, to accommodate Nephrocytium. Furthermore, we have carried out a review of previously described Nephrocytium species and based on morphological and molecular data we propose the description of Nephrocytium vieirae sp. nov. [ABSTRACT FROM AUTHOR]
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- 2021
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12. The Ototoxicity of Chloroquine and Hydroxychloroquine: A Systematic Review
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Fernandes, Carolina Pereira, Vernier, Luíza Silva, Dallegrave, Eliane, and Machado, Márcia Salgado
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- 2022
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13. How to increase access to kidney transplantation: the analysis of a Brazilian public hospital through operations management
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Silva, Ana Carolina Pereira De Vasconcelos, Spiegel, Thaís, Scavarda, Luiz Felipe, and Reis, Augusto Da Cunha
- Abstract
End-stage renal disease is one of the most costly chronic diseases for the Brazilian public health system. Dialysis is still the most commonly used procedure, even though transplantation is one of the most recommended treatments. Considering the perspective of operations management as an approach for organisational interventions, the objective of this paper was to propose a new operation model for a transplantation unit in Rio de Janeiro State focused on reducing the patients waiting times in queues. The first step was to conduct a systematic literature review. Then, the kidney transplantation process was modelled using ARIS/IDS notation, which oriented the description and analysis of the operation model of the transplantation unit. A new model was proposed, along with a list of strategic, structural and political decisions to mitigate organisational, network design and budget pass-through logic inconsistences.
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- 2022
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14. Analysis of the Excess of Papanicolaou Tests in Brazil from 2006 to 2015
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Fischer, Ana Carolina Pereira, Fischer, Eduardo Augusto Pereira, Vaz, Fernanda Brião, and Hoffmann, Júlia
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- 2022
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15. MRI of Penile Prostheses: The Challenge of Diagnosing Postsurgical Complications
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Uski, Ana Cláudia Vincenzi Raduan, Piccolo, Luciana Maksoud, Abud, Carolina Pereira, Pedroso, Maria Helena Naves Inácio, Seidel Albuquerque, Kamila, Gomes, Natália Borges Nunes, and Fernandes, José de Ávila
- Abstract
Detection and management of complications after penile prosthesis implantation are challenging, and MRI plays a crucial role as it permits evaluation of the positioning and configuration of the prosthesis component.
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- 2022
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16. Motor cortex transcranial direct current stimulation effects on knee osteoarthritis pain in elderly subjects with dysfunctional descending pain inhibitory system: A randomized controlled trial.
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Tavares, Daniela Regina Brandão, Okazaki, Jane Erika Frazao, Santana, Marcia Valéria de Andrade, Pinto, Ana Carolina Pereira Nunes, Tutiya, Karina Kuraoka, Gazoni, Fernanda Martins, Pinto, Camila Bonin, Santos, Fania Cristina, Fregni, Felipe, and Trevisani, Virginia Fernandes Moça
- Abstract
Although evidence has indicated a positive effect of transcranial direct current stimulation (tDCS) on reducing pain, few studies have focused on the elderly population with knee osteoarthritis (KOA). To evaluate whether tDCS reduces KOA pain in elderly individuals with a dysfunctional descending pain inhibitory system (DPIS). In a double-blind trial, individuals ≥ 60 years with KOA pain and a dysfunctional DPIS, we randomly assigned patients to receive 15 daily sessions of 2 mA tDCS over the primary motor cortex (anode) and contralateral supraorbital area (cathode) (M1-SO) for 20 min or sham tDCS. Change in pain perception indexed by the Brief Pain Inventory (BPI) at the end of intervention was the primary outcome. Secondary outcomes included: disability, quantitative sensory testing, pain pressure threshold and conditioned pain modulation (CPM). Subjects were followed-up for 2 months. Of the 104 enrolled subjects, with mean (SD) age of 73.9 (8.01) years and 88 (84.6%) female, 102 finished the trial. In the intention-to-treat analysis, the active tDCS group had a significantly greater reduction in BPI compared to the sham group (difference, 1.59; 95% CI, 0.95 to 2.23; P < 0.001; Cohen's d, 0.58); and, also a significantly greater improvement in CPM-pressure in the knee (P = 0.01) and CPM-pain in the hand (P = 0.01). These effects were not sustained at follow-up. The intervention was well tolerated, with no severe adverse effects. M1-SO tDCS is associated with a moderate effect size in reducing pain in elderly patients with KOA after 15 daily sessions of stimulation. This intervention has also shown to modulate the DPIS. • Fifteen daily sessions of tDCS decreases knee osteoarthritis pain in the elderly. • Motor cortex tDCS modulates the descending inhibitory pain system in the elderly. • 2 mA for 20 min of anodal tDCS is safe and well tolerated in the elderly. • tDCS alone did not induce long-term effects in the elderly with knee chronic pain. [ABSTRACT FROM AUTHOR]
- Published
- 2021
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17. Revised phylogenetic position of NephrocytiumNägeli (Sphaeropleales, Chlorophyceae), with the description of Nephrocytiaceae fam. nov. and Nephrocytium vieiraesp. nov.
- Author
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Silva, Thaís Garcia, Štenclová, Lenka, Archanjo, Naiara Carolina Pereira, and Bagatini, Inessa Lacativa
- Abstract
The common planktonic green algal genus Nephrocytiumwas traditionally assumed to have a close relationship with the genus Oocystisand accordingly has been included in the family Oocystaceae. Although the position of Nephrocytiumwithin the Oocystaceae has differed according to some authors over the years, its inclusion in the family has not been questioned. Following molecular studies of Oocystis, the Oocystaceae (including Nephrocytium) was removed from the class Chlorophyceae and placed in the Trebouxiophyceae.However, recent molecular studies of some of the former Oocystaceae members have returned them to the Chlorophyceae. These studies suggested the placement of Nephrocytiumin the Sphaeropleales, but no taxonomic positioning within the order has been determined for the genus. The relocation of Nephrocytiumagrees with a strong morphological trait – it lacks the oocystaceaean multilayered ultrastructure of the cell wall. Based on molecular markers (18S rDNA and tufA), and optical and electron microscopy, the present study aimed to establish the relationships of the genus within the Sphaeropleales. The results support the recognition of a new family, the Nephrocytiaceae, to accommodate Nephrocytium. Furthermore, we have carried out a review of previously described Nephrocytiumspecies and based on morphological and molecular data we propose the description of Nephrocytium vieiraesp. nov.
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- 2021
- Full Text
- View/download PDF
18. Short Physical Performance Battery (SPPB) score as a discriminator of dynapenic abdominal obesity among community-dwelling older adults.
- Author
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Santos, Elane Priscila Rosa dos, Silva, Caroline Fátima Ribeiro, Ohara, Daniela Gonçalves, Matos, Areolino Pena, Pinto, Ana Carolina Pereira Nunes, and Pegorari, Maycon Sousa
- Abstract
• No studies have investigated the association between DAO and physical performance; compounding this issue, there is little information on how to screen patients with DAO efficiently. • Older adults with dynapenic abdominal obesity (DAO) presented reduced physical performance, and the SPPB score was inversely associated with DAO. Cut-off points of ≤9 for SPPB scores were the most efficient for discriminating the presence of DAO in both men and women. The aim of this study is to verify the utility of using physical performance to discriminate the presence of dynapenic abdominal obesity (DAO) in older adults. This cross-sectional study was conducted with 382 community-dwelling older adults. DAO was identified when dynapenia (cut-off points of <26 kilogram-force [kgf] for men and <16 kgf for women) was detected together with abdominal obesity (waist circumference >102 cm for men and >88 cm for women). Physical performance was assessed with the Short Physical Performance Battery (SPPB). SPPB scores and DAO were inversely associated even after adjustment (OR: 0.69; 95%CI: 0.58–0.83). Cut-off points of ≤9 for SPPB scores were the most efficient for discriminating the presence of DAO in both men (AUC= 0.836; 95%CI: 0.76–0.89; sensitivity: 90.91% and specificity: 60.33%) and women (AUC= 0.677; 95%CI: 0.62–0.73; sensitivity: 73.33% and specificity: 40.91%). Physical performance assessed with SPPB can discriminate DAO and be useful for the timely identification and management of this condition in older adults. [ABSTRACT FROM AUTHOR]
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- 2021
- Full Text
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19. Transcranial direct current stimulation for fatigue in patients with Sjogren's syndrome: A randomized, double-blind pilot study.
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Pinto, Ana Carolina Pereira Nunes, Piva, Sara Regina, Vieira, Aléxia Gabriela da Silva, Gomes, Samantha Guerra Cabó Nunes, Rocha, Aline Pereira, Tavares, Daniela Regina Brandão, Santana, Márcia Valéria de Andrade, Carlesso, Cristiane, Andriolo, Adagmar, Santos, Fania Cristina, Fregni, Felipe, and Trevisani, Virgínia Fernandes Moça
- Abstract
Transcranial direct-current stimulation (tDCS) has shown promise to decrease fatigue. However, it has never been examined in primary Sjogren Syndrome (pSS). To assess the effect of a tDCS protocol on fatigue in patients with pSS. This is a parallel, double-blind pilot study (NCT04119128). Women aged 18–65 years, with pSS, on stable pharmacological therapy, with complaints of fatigue for at least three months, and with scores >5 on Fatigue Severity Scale (FSS) were included. We randomized 36 participants to receive five consecutive or sham tDCS sessions, with an intensity of 2 mA, for 20 min/day. After five tDCS sessions, fatigue severity assessed by the FSS (primary outcome) demonstrated a mean group difference of −0.85 [95% confidence interval (CI) −1.57, −0.13; effect size 0.80] favouring the active group. The active group presented significantly greater reductions in fatigue as measured by the EULAR Sjögren's Syndrome Patient Reported Index after five tDCS sessions [mean group difference: 1.40; 95%CI -2.33, −0.48; effect size 1.04]. Although there were no between-group differences in the secondary outcomes of sleep, mood and anxiety, within-group comparisons evidenced a small but significant difference in the active group for pain and sleep. There were no significant cortisol changes. All reported adverse events were mild and transitory. tDCS seems to be safe and reduce fatigue in pSS. A differential effect on pain and sleep may underlie its effects. Further studies are needed to optimise tDCS treatment strategies in pSS. • This is the first study to demonstrate that tDCS may help to manage pSS fatigue. • TDCS seems to be safe and has excellent tolerability and compliance in pSS patients. • Our results provide critical data to design future trials on tDCS in pSS patients. [ABSTRACT FROM AUTHOR]
- Published
- 2021
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20. SHORT PHYSICAL PERFORMANCE BATTERY AS A PREDICTOR OF MORTALITY AMONG OLDER ADULTS: SYSTEMATIC REVIEW WITH META-ANALYSIS
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Silva, Caroline de Fátima Ribeiro, Pereira, Larissa do Nascimento, Ohara, Daniela Gonçalves, Matos, Areolino Pena, Pinto, Ana Carolina Pereira Nunes, and Pegorari, Maycon Sousa
- Abstract
Physical performance is an essential component in the clinical assessment among older adults, and its decline as assessed by the Short Physical Performance Battery (SPPB) is associated with increased risk for hospitalization, institutionalization, falls, and disability. Although a SPPB score <10 seems to be predictive of mortality, according to previous studies, the cutoff values are heterogeneous, which makes it difficult to really know the predictive power of SPPB for mortality and the magnitude of the increase in the probability of death as the score decreases.
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- 2024
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21. Impact of sodium-glucose cotransporter-2 inhibitors-induced glucosuria in the incidence of urogenital infection on postmenopausal women with diabetes.
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Marques, Luiz Paulo José, Mendonça, Nayanne Aguiar, Müller, Lucas, André, Ana Carolina Pereira Diaz, Madeira, Eugênio Pacelle Queiroz, and Vieira, Lygia Maria Soares Fernandes
- Subjects
DIABETES in women ,POSTMENOPAUSE ,URINARY tract infections ,TYPE 2 diabetes ,GLYCOSYLATED hemoglobin ,CANAGLIFLOZIN ,SODIUM-glucose cotransporter 2 inhibitors - Abstract
Type 2 diabetes mellitus (T2DM) in postmenopausal women is associated with a high incidence of urogenital infections, which negatively impact the quality of life and increase morbidity, mortality, and health-care costs. Glucosuria is a known risk factor for these infections; therefore, it is of interest to determine if increased glucosuria secondary to sodium-glucose cotransporter-2 inhibitors (SGLT2in) impacts the incidence and severity of urogenital infections in postmenopausal women with T2DM. The study was conducted at Gaffrée Guinle University Hospital on two groups of postmenopausal women with T2DM: with and without SGLT2in therapy (n = 80 in each group). Medical records and laboratory parameters (urinary dipstick test and culture; blood glucose, glycosylated hemoglobin, and creatinine; cervical cytologic study) of all subjects were carefully assessed at baseline and thrice during the 12-month study period. We observed a significant incidence of vulvovaginitis (relative risk [RR], 2.37; 95% confidence interval [CI], 1.10–5.10; P = 0.03) and asymptomatic bacteriuria (RR, 2.47; 95% CI, 1.09–5.60; P = 0.03), but not of urinary tract infections (RR, 2.08; 95% CI, 0.74–5.81; P = 0.16), secondary to SGLT2in therapy. Genital infection was severe enough to warrant treatment discontinuation in 57.89% of patients in group 1. All urinary tract infections were of mild intensity with a good response to antibiotic therapy. Glucosuria induced by SGLT2in therapy may lead to a high incidence of urogenital infections in postmenopausal women with T2DM and can be considered a risk factor for these infections. [ABSTRACT FROM AUTHOR]
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- 2020
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22. Bilingualism for delaying the onset of Alzheimer's disease: a systematic review and meta-analysis.
- Author
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Paulavicius, Andrea M., Mizzaci, Carolina C., Tavares, Daniela R. B., Rocha, Aline P., Civile, Vinicius T., Schultz, Rodrigo R., Pinto, Ana Carolina Pereira Nunes, and Trevisani, Virginia F. M.
- Abstract
Key summary points: Aim: To assess the effects of bilingualism compared to monolingualism on the clinical manifestation of Alzheimer's Disease. Findings: Data from meta-analyses suggest that bilingual individuals exhibit Alzheimer's Disease symptoms are diagnosed later than monolingual participants. Message: Bilingualism may delay the manifestation of symptoms and diagnosis of Alzheimer's Disease. Objective: To assess the effects of bilingualism compared to monolingualism on the clinical manifestation of Alzheimer's disease. Methods: We searched the databases: MEDLINE, The Cochrane Central Register of Controlled Trials, Embase and LILACS, and searched by hand and in gray literature for studies published before September 2019. The quality of included studies was assessed using the Newcastle–Ottawa Scale. Two reviewers independently searched for studies, extracted data, and performed the quality assessment. Results: Eight studies were included in this review. Data from meta-analyses suggest that bilingual individuals with Alzheimer's disease exhibit symptoms (694 participants; mean difference (MD) (4.05 years; 95% CI: 1.87–6.22 and are diagnosed later (1012 participants; MD 2.0 years; 95% CI: 0.08–3.92) than monolingual participants. Conclusion: Bilingualism may delay the manifestation of symptoms and diagnosis of Alzheimer's disease. Further studies with more rigorous methodology are needed to improve the precision of the results. [ABSTRACT FROM AUTHOR]
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- 2020
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23. Increased aridity and chronic anthropogenic disturbance reduce litter productivity in a Caatinga dry forest.
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Kulka, Daniele Duarte, Filgueiras, Bruno K.C., dos Santos, Alice Batista, Locatelli, Anna Carolina Pereira, Domingos de França, Jamerson, Lins, Silvia Rafaela Machado, and Tabarelli, Marcelo
- Subjects
TROPICAL dry forests ,FOREST biomass ,FOREST productivity ,FOREST soils ,SANDY soils ,BIOMASS conversion ,ECOSYSTEM management - Abstract
Tropical dry forest productivity is thought to be driven by a combination of natural factors, particularly total water availability and seasonality. However, most of the world's dry forests have been converted into forest successional mosaics by a combination of slash-and-burn agriculture and exploitation of forest products, which has potential impacts for forest productivity. Here, we examined litter production, nutrient concentrations and fluxes across regenerating and old-growth stands of a Caatinga dry forest during a 48-mo period, assessing the impact of annual rainfall, forest aboveground biomass, soil fertility, forest successional status, stand age and chronic anthropogenic disturbance. We found our sites to have low litter productivity, producing 0.193 ± 0.016 Mg ha
−1 yr−1 (mean ± SE) of litter. Moreover, litter production was highly seasonal (> 90% during the dry season), and varied substantially across forest stands (from 0.0035 to 0.564 Mg ha−1 yr−1 ), but with no differences relative to forest successional status; i.e. similar litter production in regenerating and old-growth stands. Litter production was affected by precipitation, soil fertility and chronic anthropogenic disturbance. Litter nutrient concentration was highly variable across forest stands, but concentration responded very little to our focal drivers. Litter N-concentration was relatively high, while P was very low resulting in a small flux to the soil via litter decomposition. In contrast to litter nutrient concentrations, nutrient fluxes were more predictable, particularly considering forest successional status. Our results suggest that Caatinga dry forest on sandy soils is a low-productivity ecosystem, probably due to a combination of natural and anthropogenic drivers. • Natural and human-related drivers can alter litter production across dry forests. • We examined litter production and nutrient concentrations/ fluxes in a dry forest. • Caatinga dry forest on sandy soils is a low-productivity ecosystem. • Litter nutrient concentration was highly variable across forest stands. • Litter production was affected by precipitation, soil fertility and human disturbance. [ABSTRACT FROM AUTHOR]- Published
- 2024
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24. Impact of sodium-glucose cotransporter-2 inhibitors-induced glucosuria in the incidence of urogenital infection on postmenopausal women with diabetes
- Author
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Marques, Luiz Paulo José, Mendonça, Nayanne Aguiar, Müller, Lucas, André, Ana Carolina Pereira Diaz, Madeira, Eugênio Pacelle Queiroz, and Vieira, Lygia Maria Soares Fernandes
- Abstract
ABSTRACTBackgroundType 2 diabetes mellitus (T2DM) in postmenopausal women is associated with a high incidence of urogenital infections, which negatively impact the quality of life and increase morbidity, mortality, and health-care costs. Glucosuria is a known risk factor for these infections; therefore, it is of interest to determine if increased glucosuria secondary to sodium-glucose cotransporter-2 inhibitors (SGLT2in) impacts the incidence and severity of urogenital infections in postmenopausal women with T2DM.MethodsThe study was conducted at Gaffrée Guinle University Hospital on two groups of postmenopausal women with T2DM: with and without SGLT2in therapy (n = 80 in each group). Medical records and laboratory parameters (urinary dipstick test and culture; blood glucose, glycosylated hemoglobin, and creatinine; cervical cytologic study) of all subjects were carefully assessed at baseline and thrice during the 12-month study period.ResultsWe observed a significant incidence of vulvovaginitis (relative risk [RR], 2.37; 95% confidence interval [CI], 1.10–5.10; P= 0.03) and asymptomatic bacteriuria (RR, 2.47; 95% CI, 1.09–5.60; P= 0.03), but not of urinary tract infections (RR, 2.08; 95% CI, 0.74–5.81; P= 0.16), secondary to SGLT2in therapy. Genital infection was severe enough to warrant treatment discontinuation in 57.89% of patients in group 1. All urinary tract infections were of mild intensity with a good response to antibiotic therapy.ConclusionGlucosuria induced by SGLT2in therapy may lead to a high incidence of urogenital infections in postmenopausal women with T2DM and can be considered a risk factor for these infections.
- Published
- 2020
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25. Rehabilitation Interventions for Shoulder Dysfunction in Patients With Head and Neck Cancer: Systematic Review and Meta-Analysis
- Author
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Almeida, Kleicyane Aguiar Meireles, Rocha, Aline Pereira, Carvas, Nelson, and Pinto, Ana Carolina Pereira Nunes
- Published
- 2020
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26. What do Cochrane systematic reviews say about telemedicine for healthcare?
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Queiroz Flumignan, Carolina Dutra, da Rocha, Aline Pereira, Nunes Pinto, Ana Carolina Pereira, Martins Milby, Keilla Machado, Rodrigues Batista, Mayara, Nagib Atallah, Álvaro, and Saconato, Humberto
- Published
- 2019
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- View/download PDF
27. Alternative Method for Glyphosate Determination in Unroasted Green Coffee Beans by Liquid Chromatography Tandem Mass Spectrometry (LC–MS/MS)
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Paiva, Ana Carolina Pereira, de Assis, Emanuel Carvalho, d’Antonino, Leonardo, de Queiroz, Maria Eliana Lopes Ribeiro, and da Silva, Antonio Alberto
- Abstract
This research proposes an alternative method to detect and quantify glyphosate residues in unroasted green coffee beans by LC–MS/MS. The sample preparation was conducted without derivatization steps, with integrated cleanup, which improves the analytical method’s frequency. Validation results were consistent with the requirements of the regulatory guidelines employed. Specificity, linearity (r2= 0.9991), precision (RSD ≤ 9%), and recovery (92–112%) were ensured, with a satisfactory limit of quantification (LOQ = 0.48 mg kg–1). These data demonstrate that the method is suitable for monitoring glyphosate residues in unroasted coffee beans while offering simplicity and speed in sample preparation. The method was applied to analyze authentic unroasted coffee bean samples, in which two of them were contaminated with glyphosate (
- Published
- 2024
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28. Physiological quality of seeds of white oat cultivars in response to trinexapac-ethyl application.
- Author
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Bizzarri Bazzo, José Henrique, Barbosa, André Prechlak, Cardoso, Carolina Pereira, Zucareli, Claudemir, and de Batista Fonseca, Inês Cristina
- Abstract
Copyright of Revista Ciência Agronômica is the property of Revista Ciencia Agronomica and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2018
- Full Text
- View/download PDF
29. Treinamento muscular inspiratório em crianças sob ventilação mecânica: revisão da literatura.
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PINTO, Ana Carolina Pereira Nunes, BARBOSA, José Luis Rodrigues, and JOHNSTON, Cintia
- Published
- 2018
30. Nursing Diagnoses of the Homeless Population in Light of Self-care Theory.
- Author
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da Silva, Felicialle Pereira, de Assis Siqueira Paiva, Francisco, Guedes, Carolina Pereira, da Silva Frazão, Iracema, Vasconcelos, Selene Cordeiro, and da Costa Lima, Murilo Duarte
- Abstract
BACKGROUND A growing number of people find themselves in conditions of extreme poverty, which often makes living on the streets the only option. Living conditions in this setting exert a direct impact on health and self-care. Health care for the homeless population should be planned in an interdisciplinary and intersectoral manner. In this context, nursing diagnoses constitute an essential part of the systemization of care. OBJECTIVES The aims of the present study were to identify nursing diagnoses of a homeless population and propose nursing interventions based on the findings in light of the Nursing Outcomes Classification and Nursing Interventions Classification. DESIGN AND SETTING A descriptive, cross-sectional study with a quantitative approach was conducted on the streets of the city of Recife in northeastern Brazil. PARTICIPANTS The sample consisted of 274 male and female adult homeless individuals. METHODS Data collection involved the administration of a semi-structured interview, the Alcohol, Smoking and Substance Involvement Screening Test and the International Neuropsychiatric Interview. RESULTS The most prevalent diagnoses were related to risk-prone health behaviors (78.1%), inadequate health maintenance (67.1%), along with sleep deprivation (100%), feelings of hopelessness (100%) and low self-esteem (99%). CONCLUSIONS The experience enabled the identification of the peculiarities of the population, bringing nursing practice closer to health promotion for the homeless. Adequate public policies and training for health teams are needed to address the health needs of the homeless population. [ABSTRACT FROM AUTHOR]
- Published
- 2018
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31. Prevalência e fatores associados à autopercepção corporal em escolares do nordeste brasileiro.
- Author
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Figueroa Pedraza, Dixis, da Cunha Sousa, Carolina Pereira, and Alves de Olinda, Ricardo
- Abstract
Copyright of Revista Eletrônica de Enfermagem is the property of Revista Eletronica de Enfermagem and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2018
- Full Text
- View/download PDF
32. Estado nutricional e hábitos alimentares de escolares de Campina Grande, Paraíba, Brasil.
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Pedraza, Dixis Figueroa, Silva, Franciely Albuquerque, Silva de Melo, Nadinne Lívia, Neves Araujo, Erika Morganna, and da Cunha Sousa, Carolina Pereira
- Abstract
Copyright of Revista Ciência & Saúde Coletiva is the property of Associacao Brasileira de Pos-Graduacao em Saude Coletiva and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2017
- Full Text
- View/download PDF
33. Ampliação do acesso à saúde na região mais vulnerável do estado de São Paulo, Brasil: reflexo do Programa Mais Médicos?
- Author
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da Silva, Bruna Pontes, Stockmann, Denise, de Souza Lúcio, Donavan, Henna, Elaine, da Rocha, Maria Carolina Pereira, and Junqueira, Fábio Miranda
- Abstract
Copyright of Revista Ciência & Saúde Coletiva is the property of Associacao Brasileira de Pos-Graduacao em Saude Coletiva and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2016
- Full Text
- View/download PDF
34. Expanding health access in the more vulnerable region in the state of São Paulo, Brazil: is this a reflection of the Mais Médicos (More Doctors) Program?
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da Silva, Bruna Pontes, Stockmann, Denise, de Souza Lúcio, Donavan, Henna, Elaine, da Rocha, Maria Carolina Pereira, and Miranda Junqueira, Fábio
- Subjects
HEALTH services accessibility ,MEDICAL care ,FAMILY health ,FAMILY medicine ,PRIMARY health care ,HEALTH status indicators - Abstract
The Mais Médicos (More Doctors) Program seeks to broaden access to health by providing medical professionals, investments in health units and multi-professional integration geared to the Family Health Strategy. Vale do Ribeira includes 25 cities and is among the most vulnerable regions in São Paulo. It has been allocated 41 physicians from the Program. This study is to evaluate access to health, comparing health indicators before and after the Program. We collected data from DATASUS, SIAB, and the Ministry of Health. There was a marked increase in the number of appointments for infants under one year of age, adults, the elderly, STD/HIV patients and group patient care. There was a decrease in appointments outside the catchment area, as well as hospital admissions for other causes, mothers exclusively breastfeeding their infants up to four months. We concluded that after deployment of the Program, there was an increase in health access and health promotion focused on an area that presents an enormous challenge for Primary Health Care (PHC). It would seem that, since this is a high vulnerability area with a large area for care, hospital admissions for PHC care-sensitive conditions, as well as referrals for secondary services, did not decrease. [ABSTRACT FROM AUTHOR]
- Published
- 2016
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35. Prevalence of stunting and overweight/obesity among Brazilian children according to different epidemiological scenarios: systematic review and meta-analysis.
- Author
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da Cunha Sousa, Carolina Pereira, de Olinda, Ricardo Alves, and Figueroa Pedraza, Dixis
- Published
- 2016
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36. Hidden diversity in Selenastraceae (Sphaeropleales, Chlorophyceae): Molecular phylogeny revealed a nannoplanktonic species, with the description of Viridiparva madeirensis gen. et sp. nov.
- Author
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Garcia, T.S., Bock, Christina, Bagatini, Inessa Lacativa, Archanjo, Naiara Carolina Pereira, Sant'anna, Célia Leite, and Vieira, Armando Augusto Henriques
- Abstract
The simple morphology of the members of the family Selenastraceae, common in freshwater phytoplankton, has led to misidentifications. But the use of molecular tools is untangling their phylogeny and unveiling new genera and species hidden under the same morphotype or overlooked by microscopic analysis. Here we propose a description of Viridiparva madeirensis gen. et sp. nov., a small Selenastraceae member, based on the study of three strains by light, scanning and transmission microscopy and 18S rDNA and rbc L phylogenies. The phylogenetic analyses by 18S rDNA and rbc L show, respectively, that the closest relatives to Viridiparva madeirensis are Monoraphidium dybowskii and Raphidocelis microscopica , but with no or low statistical support. V. madeirensis is smaller than M. dybowski and has no cell wall incrustations typical for Raphidocelis. Thus, phylogeny and morphological analyses indicate a novel lineage within Selenastraceae. Furthermore, also reinforce the necessary revision of the genera within Selenastraceae, as Monoraphidium and Raphidocelis. Therefore study contributes to clarify the phylogeny and taxonomy of the family and add genetic sequences of neglected nanophytoplankton to GenBank, including one strain with known potential for biodiesel production. • Viridiparva madeirensis is a new genera and species described for a green microalga • Phylogeny and morphological analyses indicate a novel lineage within Selenastraceae • Elucidation of the taxonomy of a strain with known potential for biodiesel production [ABSTRACT FROM AUTHOR]
- Published
- 2022
- Full Text
- View/download PDF
37. Opal phytolith and isotopic studies of "Restinga" communities of Maricá, Brazil, as a modern reference for paleobiogeoclimatic reconstruction.
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dos Santos, Cátia Pereira, Gomes Coe, Heloisa Helena, Borrelli, Natalia, da Silva, André Luiz Carvalho, de Oliveira Furtado de Sousa, Leandro, Medina Ramos, Yame Bronze, Silvestre, Carolina Pereira, and Seixas, Amanda Pacheco
- Subjects
PHYTOLITHS ,CARBON isotopes ,PLANT communities ,ISOTOPES -- Environmental aspects ,PLANT species ,PLANT species diversity - Abstract
Copyright of Brazilian Journal of Oceanography is the property of Instituto Oceanografico da Universidade de Sao Paulo and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2015
- Full Text
- View/download PDF
38. USO DE CÉLULAS-TRONCO NO TRATAMENTO DE FÍSTULA ANORRETAL COMPLEXA POR DOENÇA DE CROHN: UM RELATO DE CASO
- Author
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de Lara, Ana Carolina Pereira, de Lara, Maria Eduarda Pereira, de Lara, Bárbara Pereira, Endo, Eduardo, de Lara, Leonardo Pereira Pegoraro, Leonardi, Stephani Fontanelli, da Silva, Emanuele Caroline, and Filho, Valdomiro Garbugio
- Published
- 2022
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39. FÍSTULA ANORRETAL EXTRAESFINCTERIANA: UM DESAFIO TERAPÊUTICO
- Author
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Carvalho, Raissa José de França, Werneck, Sabryna de Lacerda, de Sousa, Ana Carolina Pereira, Pincinato, André Luigi, Sabino, Walfrido, and Daher, Marina Corrêa
- Published
- 2022
- Full Text
- View/download PDF
40. Crescimento e deficiências de micronutrientes: perfil das crianças assistidas no núcleo de creches do governo da Paraíba, Brasil.
- Author
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Pedraza, Dixis Figueroa, Dantas Rocha, Ana Carolina, and da Cunha Sousa, Carolina Pereira
- Subjects
TRACE element deficiency diseases in children ,DAY care centers ,GROWTH of children ,BODY mass index ,CROSS-sectional method - Abstract
Copyright of Revista Ciência & Saúde Coletiva is the property of Associacao Brasileira de Pos-Graduacao em Saude Coletiva and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2013
- Full Text
- View/download PDF
41. Light Cementitious Composites with Wastes from the Footwear Industry
- Author
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Dantas, Carolina Pereira, Leal, Antônio Farias, Barbosa, Normando Perazzo, and Torres, Sandro Marden
- Abstract
Emphasizing the cost reduction and the sustainable development, the construction sector, is more and more, in search of the possibility of the use of non-conventional materials produced with industrial waste or from renewable sources. The large volume of industrial waste constitutes a serious environmental problem. The use of sisal fiber with fiber-cement reinforcement is strategically for the national development, because Brazil is the largest producer and exporter of this fiber. The present study aims to contribute to the viability of the use of SBR waste in the footwear industry and the sisal fiber, in the development of light cementitious composites. The mechanical and physical properties of the composites were evaluated, with cement or plaster matrix, varying the levels of SBR waste incorporation and the production technique, through tests of absorption and flexural strength. The viability of the materials was proved for a possible use in the production of light construction elements, such as plates and panels, for thermal protection of masonry, seeking energy efficiency of buildings.
- Published
- 2014
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42. PRÁTICAS CULTURAIS JUVENIS: MÁSCARAS CONTEMPORÂNEAS.
- Author
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da Silva Rosa, Ana Carolina Pereira, Ferreira, Helenice Mirabelli Cassino, and Oswald, Maria Luiza Magalhães Bastos
- Subjects
VIDEO games & teenagers ,AVATARS (Virtual reality) ,ROLE playing ,HEDONISM - Abstract
Copyright of Revista da FAEEBA - Educação e Contemporaneidade is the property of Universidade do Estado da Bahia and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2010
43. Chimerism 47,XY, + 8/46,XX: Follow-up for 11 Years
- Author
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de Carvalho, Acácia Fernandes Lacerda, Pitanga, Paula Monique Leite, Alves, Esmeralda Santos, Miguel, Diego Santana Chaves Geraldo, Santo, Laila Damasceno Espirito, de Araújo, Ana Eliete Fernandes, Ornellas, Ana Carolina Pereira, and Toralles, Maria Betânia Pereira
- Published
- 2022
- Full Text
- View/download PDF
44. Implementation of Recycling Routes for Scanning Probe Microscopy Tips
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Souza, Carolina Pereira de and Andrade, Margareth Spangler
- Abstract
In this work, effective, yet simple, recycling mechanisms for used scanning probe microscopy (SPM) tips were implemented. Comprising a tip profile characterization methodology and specific cleaning procedures, which decontaminate SPM tips whether the contamination nature is known or not, such routes were optimized during numerous tests with brand new, previously used, and already discarded categories of SPM tips. The results show that if the used tip suffered contamination only, but no physical damages, during its scanning lifetime, it becomes readily available for reutilization after the cleansing process, characterizing a recycling route. On the other hand, if the tip went through wear and breakages during its utilization, it still can be decontaminated, but may not be directly reutilized due to its inadequate physical profile. Nevertheless, the methodology developed in this work may yet be applied as part of a more complex recycling route.
- Published
- 2002
45. Immune status and risk perception of acquisition of vaccine preventable diseases among health care workers.
- Author
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Dinelli, Maria Isabel Saraiva, Moreira, Thais das Neves Fraga, Paulino, Érica Regina Cruz, da Rocha, Maria Carolina Pereira, Graciani, Flávia Bracale, and de Moraes-Pinto, Maria Isabel
- Abstract
Risk perception of acquiring vaccine preventable diseases and the immune status of 187 health care workers (HCW) from a high-complexity university hospital in São Paulo, Brazil, were assessed. The vaccine preventable diseases more cited as at risk for acquisition were hepatitis B (94.1%), influenza (92.5%), meningococcal disease (90.3%), tuberculosis (85.0%), and varicella (72.7%). Previous disease or vaccination reported by HCW were hepatitis B (82.4%), tetanus (87.7%), diphtheria (81.8%), measles (86.6%), mumps (85.6%), rubella (85.0%), varicella (82.9%), and influenza (35.8%). One third of HCW reported previous percutaneous or mucosal occupational accidents, and 83.6% had notified the event to the Hospital Infection Control Committee. Despite good risk perception of acquiring vaccine preventable diseases, only 35.8% of individuals were fully immunized. Efforts should be made to increase influenza vaccination coverage among all professionals and to reduce the number of nonreported accidents, especially among physicians. [Copyright &y& Elsevier]
- Published
- 2009
- Full Text
- View/download PDF
46. Effects of Transcranial Direct Current Stimulation on Knee Osteoarthritis Pain in Elderly Subjects With Defective Endogenous Pain-Inhibitory Systems: Protocol for a Randomized Controlled Trial.
- Author
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Brandao Tavares, Daniela Regina, Frazao Okazaki, Jane Erika, Rocha, Aline Pereira, De Andrade Santana, Marcia Valeria, Nunes Pinto, Ana Carolina Pereira, Civile, Vinicius Tassoni, Santos, Fania Cristina, Fregni, Felipe, and Moça Trevisani, Virginia Fernandes
- Subjects
TRANSCRANIAL direct current stimulation ,OSTEOARTHRITIS ,ELECTROTHERAPEUTICS ,ARTHRITIS ,RANDOMIZED controlled trials - Abstract
Background: Knee osteoarthritis (OA) has been the main cause behind chronic pain and disabilities in the elderly population. The traditional treatment for knee OA pain currently concerns a number of combinations of pharmacological and nonpharmacological therapies. However, such combinations have displayed little effects on a significant group of subjects. In addition to this, pharmacological treatments often cause adverse effects, which limits their use on this population. Previous studies showed that chronic knee OA pain may be associated with maladaptive compensatory plasticity in pain-related neural central circuits indexed by a defective descending pain- inhibitory system. Transcranial direct current stimulation (tDCS) can revert some of these maladaptive changes, thus decreasing chronic pain sensation. Numerous studies have demonstrated that the use of anodal tDCS stimulation over the primary motor cortex (M1) has positive effects on chronic neuropathic pain. Yet, data on OA pain in elderly patients, including its effects on the endogenous pain-inhibitory system, remain limited. Objective: The objective of this study is to evaluate the efficacy of tDCS in reducing pain intensity caused by knee OA in elderly subjects with defective endogenous pain-inhibitory systems. Methods: We designed a randomized, sham-controlled, single-center, double-blinded clinical trial. Patients with knee OA who have maintained a chronic pain level during the previous 6 months and report a pain score of 4 or more on a 0-10 numeric rating scale (NRS) for pain in that period will undergo a conditioned pain modulation (CPM) task. Participants who present a reduced CPM response, defined as a decrease in NRS during the CPM task of less than 10%, and meet all of the inclusion criteria will be randomly assigned to receive 15 sessions of 2 mA active or sham tDCS for 20 minutes. A sample size of 94 subjects was calculated. The Brief Pain Inventory pain items will be used to assess pain intensity as our primary outcome. Secondary outcomes will include pain impact on functioning, mobility performance, quality of life, CPM, pressure pain threshold, touch-test sensory evaluation, and safety. Follow-up visits will be performed 2, 4, and 8 weeks following intervention. The data will be analyzed using the principle of intention-to-treat. Results: This study was approved by the institutional review board with the protocol number 1685/2016. The enrollment started in April 2018; at the time of publication of this protocol, 25 subjects have been enrolled. We estimate we will complete the enrollment process within 2 years. Conclusions: This clinical trial will provide relevant data to evaluate if anodal tDCS stimulation over M1 can decrease chronic knee OA pain in elderly subjects with defective CPM. In addition, this trial will advance the investigation of the role of central sensitization in knee OA and evaluate how tDCS stimulation may affect it. [ABSTRACT FROM AUTHOR]
- Published
- 2018
- Full Text
- View/download PDF
47. Elephantiasis and Directed Occupational Rehabilitation
- Author
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Maria Pereira de Godoy, Jose, Jose Pereira de Godoy, Henrique, Carolina Pereira de Godoy, Ana, and de Fátima Guerreiro Godoy, Maria
- Abstract
The aim of the present study was to demonstrate the cure of elephantiasis over a ten-year follow-up period and novel discoveries with directed occupational rehabilitation. A 66-year-old female patient with a history of bilateral lower limb lymphedema reported the aggravation of the condition over the years, reaching stage III (elephantiasis). The physical examination confirmed elephantiasis. The circumference of the left lower limb was 106 cm. Her body weight was 106 kilograms, height was 160 cm, and the body mass index (BMI) was 41.6 kg/m2. The patient was submitted to intensive treatment for three weeks, which led to a 21-kg reduction in weight and 66 cm reduction in leg circumference. Ten years after treatment, the patient has maintained the results with the compression stockings. Elephantiasis can be cured, although lymphedema cannot. The cure of elephantiasis depends on maintaining the treatment of lymphedema after normalization or near normalization. Directed occupational therapy stimulates the search for new activities and a life closer to normality.
- Published
- 2019
- Full Text
- View/download PDF
48. Lymph Drainage of Posttraumatic Edema of Lower Limbs
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Carolina Pereira de Godoy, Ana, Ocampos Troitino, Rodrigo, de Fátima Guerreiro Godoy, Maria, and Maria Pereira de Godoy, José
- Abstract
Objective. The present study was aimed at evaluating the use of mechanical and manual lymphatic therapy as a treatment for lymphedema resulting from orthopedic surgery that became painful after an episode of erysipelas. Case Report. A 70-year-old male patient suffered direct trauma resulting in a compound fracture of the tibia and fibula of the left leg. He was treated with an external fixator for four months followed by plaster cast immobilization for three weeks. He presented with fever and paresthesia in the lower left limb that resulted in an episode of erysipelas, and the patient evolved with painful lymphedema. Treatment using the Godoy and Godoy technique was proposed, including manual and mechanical lymphatic therapy. Water displacement volumetry was used to quantify the leg size reduction. Results. After 10 sessions of therapy, the patient presented a significant reduction in the limb volume and remission of symptoms. Conclusions. The method used may be a promising option for the treatment of posttraumatic edemas with pain.
- Published
- 2018
- Full Text
- View/download PDF
49. Gene Expression Profiling in the Classification of Acute Leukemia Brazilian Patients
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Melo, Carolina Pereira de Souza, Campos, Catharina Brant, Dutra, Alvaro Pimenta, Atalla, Angelo, Dudeque Pianovski, Mara Albonei, Carbone, Edna Kakitani, Quintão Lares, Luciana, Souza, Hélio Moraes, Silva, Shirlei Octacilio, Ferreira, Alessandro Clayton de Souza, and Assumpcao, Juliana Godoy
- Abstract
No relevant conflicts of interest to declare.
- Published
- 2014
- Full Text
- View/download PDF
50. Gene Expression Profiling in the Classification of Acute Leukemia Brazilian Patients
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Melo, Carolina Pereira de Souza, Campos, Catharina Brant, Dutra, Alvaro Pimenta, Atalla, Angelo, Dudeque Pianovski, Mara Albonei, Carbone, Edna Kakitani, Quintão Lares, Luciana, Souza, Hélio Moraes, Silva, Shirlei Octacilio, Ferreira, Alessandro Clayton de Souza, and Assumpcao, Juliana Godoy
- Abstract
In the past few decades, genetic data has become increasingly important for acute leukemia diagnosis and patients stratification. Indeed, the present World Health Organization (WHO) leukemia classification system is largely based upon genetically defined subgroups. Gene expression profile (GEP) may correctly predict most genetic leukemia subtypes, but so far no GEP report has evaluate patients from Latin America. In the present study, we used gene expression microarray data to build an acute leukemia classifier. Bone marrow samples were collected from 231 individuals at diagnosis, 110 presented de novo acute myeloid leukemia (AML), 97 had de novo acute lymphoid leukemia (ALL) and the remaining 24 were controls who had other conditions including chronic leukemias or non-hematological diseases. GEP was evaluated based on mRNA expression signatures obtained with the Sure Print G3 Human GE (60k) system (Agilent Technologies). k-nearest neighbors prediction algorithm was applied and the top 60 informative genes were selected for each of the most prevalent genetic subtypes (T-ALL, B-ALL BCR-ABL, B-ALL ETV6-RUNX1, B-ALL TCF3-PBX1, AML PML-RARa, AML RUNX1-RUNX1T1, AML FLT3-ITD, AML NPM1mut). The less prevalent groups such as MLL rearranged and CBFB-MYH11 were not included in the classifier because of the low number of patients carrying these aberrations in our cohort. Performance of each prediction model was assessed by leave-one-out crossvalidation through the GenePattern platform (Broad Institute). The average classifier accuracy was 94.75%. Higher accuracy and precision were achieved for T-ALL (99%/96%) and AML PML-RARa (97%/97%). However, for ALL BCR-ABL, AML FLT3-DIT and AML NPM1mutthe gene signature had low precision rates (74%, 66% and 80%, respectively). The data presented here confirm that a single platform of gene expression followed by bioinformatic analysis can correctly classify genetic subgroups, but a refinement of the classifier developed is needed in order to improve the detection of heterogeneous entities such as BCR-ABL or FLT3-ITD carriers.
- Published
- 2014
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