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Die Messung von relativem regionalem Blutvolumen (rCBV) mittels MRT in Meningeomen durch die Verwendung von (a) Gradientenechosequenzen und (b) Echo-Planar-Imaging (EPI) Sequenzen zu vergleichen. Insgesamt 18 Patienten wurden an einem Siemens-1. 5T-Gerät untersucht. Bei den Gradientenechosequenzen (n=12, TR/TE=44/22 ms, Flipwinkel=10°) bzw. EPI-Sequenzen (n=6, TR/TE=1500/54 ms) wurde ein Bolus von 0.2 mmol/kg KG von Gd-DTPA mit einer Injektionsrate von 5 ml/s maschinell injiziert. Aus den aufgenommenen Bilddaten wurden pixelweise ein Blutvolumenbild berechnet. Das Verhältnis des Tumor-rCBV zum rCBV der grauen Hirnsubstanz betrug im Mittel 3.01±1.18 (3.07±1.39 bei der FLASH-Sequenz und 2.84±0.94 bei der EPI-Sequenz). Das Verhältnis des rCBV der grauen Substanz zum rCBV der weiäen Substanz betrug im Mittel 2,79±0,76 bei der FLASH-Sequenz, und im Mittel 3.04±1.31 bei der EPI-Sequenz. Dert-Test für Differenzbildung war nicht signifikant (P>0.05). Das mittlere Blutvolumen für Meningeome betrug gemittelt 14,5 ml/100 g. Meningeome zeigen ein inhomogen erhähtes Blutvolumen gegenüber der grauen Hirnsubstanz. Rekonstruktionen aus Gradientenecho- wie EPI-Sequenzen zeigen vergleichbare Blutvolumenwerte.

This study was designed to determine the optimal contrast protocol for 4-detector-row computed tomography angiography of the heart.

The authors investigate the validity of regional relative cerebral blood volume (rCBV) versus maximum concentration and subtraction signal intensity (SI) maps using simple reconstruction modes in patients with gliomas.

The purpose of this study was to evaluate the utility of magnetic resonance (MR) relative cerebral blood volume (rCBV) maps for studying regional hemodynamic changes in interictal and ictal epilepsy patients. Ten epilepsy patients were examined on a 1.5 T MR system. Nine patients were investigated interictally and one patient ictally. In the nine interictal patients, the dynamic plane was defined coronally through the hippocampus symmetrically. For the ictal patient, an axial dynamic plane was defined and the patient was scanned during seizure. Positron emission tomography (PET) studies were performed in 8 of the 10 patients. Lower rCBV of the left hippocampus was predicted by rCBV maps in seven of the nine interictal patients. The mean ratios of rCBV were 1.96 for left hippocampus/white matter and 2.49 for right hippocampus/ white matter. The difference between these two ratios is statistically significant (P = 0.01, t-test). In two of the nine interictal temporal lobe epilepsy patients, lower rCBV areas were observed in the right hippocampus. In the ictal patient, the regional rCBV map demonstrated increased blood volume in the lesions. In eight of eight patients who underwent PET studies, MR rCBV findings were consistent with PET findings. The results show that regional hemodynamic changes in epilepsy can be evaluated with dynamic contrast-enhanced MR imaging. MR rCBV maps are sensitive to characterize seizure foci both ictally and interictally.J. Magn. Reson. Imaging 1999; 9:435–440. © 1999 Wiley-Liss, Inc.

The purpose of this study was to evaluate the utility of magnetic resonance (MR) relative cerebral blood volume (rCBV) maps for studying regional hemodynamic changes in interictal and ictal epilepsy patients. Ten epilepsy patients were examined on a 1.5 T MR system. Nine patients were investigated interictally and one patient ictally. In the nine interictal patients, the dynamic plane was defined coronally through the hippocampus symmetrically. For the ictal patient, an axial dynamic plane was defined and the patient was scanned during seizure. Positron emission tomography (PET) studies were performed in 8 of the 10 patients. Lower rCBV of the left hippocampus was predicted by rCBV maps in seven of the nine interictal patients. The mean ratios of rCBV were 1.96 for left hippocampus/white matter and 2.49 for right hippocampus/ white matter. The difference between these two ratios is statistically significant (P= 0.01, t‐test). In two of the nine interictal temporal lobe epilepsy patients, lower rCBV areas were observed in the right hippocampus. In the ictal patient, the regional rCBV map demonstrated increased blood volume in the lesions. In eight of eight patients who underwent PET studies, MR rCBV findings were consistent with PET findings. The results show that regional hemodynamic changes in epilepsy can be evaluated with dynamic contrast‐enhanced MR imaging. MR rCBV maps are sensitive to characterize seizure foci both ictally and interictally.J. Magn. Reson. Imaging 1999; 9:435–440. © 1999 Wiley‐Liss, Inc.

The authors compare the value of a new circularly polarized body array coil (BAC) system with a standard body coil (BC) for high-resolution magnetic resonance imaging of the female pelvis.