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Robust associations of self-control with successful goal pursuit have been amply demonstrated. Much less is known about the psychological processes that occur when people grapple with self-control conflicts and that may contribute to successful goal pursuit. Influenced by the neighboring fields of emotion regulation and coping, self-regulatory flexibility has been identified as one of such potential processes. The aim of this review is to provide an overview of selected models of regulatory flexibility, empirical evidence on associations with self-regulatory success, and to identify avenues for future research.