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Background: Double congenital tracheoesophageal fistula (TEF) without esophageal atresia, known as double H-type fistula, is an extremely uncommon malformation. Due to its nonspecific symptoms and the small size of the fistula in infancy, H-type tracheoesophageal fistula is rarely diagnosed in the neonatal period and is also challenging to repair. Case presentation: We report a rare case of double H-type tracheoesophageal fistula in a 2-day-old newborn, identified with a time-lapse and repaired separately. The diagnosis was established through repeated bronchoscopy, with methylene blue injected through an esophagoscope. A right thoracotomy was performed to undertake the surgical repair after cannulating the fistula with a vascular guide wire. Five months later, the infant, who had a history of recurrent episodes of coughing and shortness of breath, was diagnosed with acute respiratory distress, and a second TEF was detected by bronchoscopy. A cervical incision was used to repair the second H-type fistula. Conclusions: Double H-type tracheoesophageal fistula should be considered while correcting a tracheoesophageal fistula, especially if the symptoms continue after the first operation. Repeated radiological contrast studies and bronchoscopy with methylene blue injected through an esophagoscope help the early diagnosis. [ABSTRACT FROM AUTHOR]

The public's health depends on a reliable drug supply chain. Recently, the number of drug counterfeit has increased drastically, resulting in thousands of victims suffering from poisoning and/or treatment failures, which have resulted in new expectations on drug supply chain traceability. Indeed, the drug supply chain involves many parties having heterogeneous interests and are usually reluctant to share traceability data with each other. Furthermore, existing traceability and provenance systems for drug supply chains suffer from separated data storage, lack of information sharing transparency, and trust. Decentralized blockchain-based solutions are advocated to address these limitations by realizing decentralized trustless systems. In this work, we present a fully decentralized, blockchain-based drug traceability solution, worthy of seamless integrating IoT devices throughout the chain. It uses both smart contracts and decentralized off-chain storage to remove the need for middleman and to provide trusted, secure and immutable transaction history. Moreover, to preserve the traceability of drugs, it ensures and enforces data provenance and data integrity in the proposed IoT environment by using blockchain Non-Fungible Tokens (NFTs). We give a test and validation of the approach's effectiveness in enhancing drug traceability supply chains, as well as an analysis of the approach's costs and security. [ABSTRACT FROM AUTHOR]

Research in the field of Higher Education in Emergencies (HEiE) starts to question the imposed Global North-centred perspective which arrives with ready-made solutions, considering refugees as objects of intervention rather than subjects of transformation. Leveraging the broader topics of Open Science and Open Education, this paper pioneers a new approach to scientific cooperation, fostering values of Openness in refugee higher education. It specifically addresses HEiE in Niger, Africa, in a training of trainers' programme. It is designed in a participatory manner involving academics from the Global South and Global North, refugees who are themselves educators, and NGOs. Taking the form of a Certificate of Open Studies (COS), the training empowers refugees as enabled change agents, capable of making sense of diverse knowledge systems to transform their reality. Preliminary understanding of Open Cooperation is shared through a conceptual framework, Empowering refugees through liberation-oriented education. It addresses sustainability at the ontological and epistemic levels and relies on four main dimensions: Epistemologies of the South, Openness, Common good and Education as empowerment. [ABSTRACT FROM AUTHOR]

Background: Intussusception is commonly idiopathic in children. Pathologic lead points (PLP) especially intestinal tumors (IT) are extremely rare. The diagnosis of intussusception secondary to pediatric IT is difficult due to the non-specific nature of symptoms. Its management remains a challenge. We report here four pediatric cases of intussusception secondary to IT lesions in order to analyze the clinical and therapeutic characteristics of this unusual condition. Case presentations: Four children were diagnosed and operated in our center for intussusception secondary to IT during the period from February 2017 to February 2021. Patients' demographics, clinical presentations, investigations, operative data, and postoperative outcome were recorded and analyzed. There were three girls and one boy. Ages ranged between 1 and 8 years (average of 5.5 years). Intermittent abdominal pain with acute exacerbation and vomiting were the main clinical signs. Radiologic investigations showed the intussusception in all cases but the tumor lead point was evident only during the surgical exploration in most cases. All patients underwent surgical treatment with intussusception reduction and mass removal. Pathological examination of these masses revealed: submucosal intestinal lipoma (1 case), hamartomatous polyposis (2 cases), and Burkitt's lymphoma (1 case). For this last case, adjuvant chemotherapy was also needed. The postoperative period was uneventful in all cases. Conclusion: Pediatric intussusception secondary to IT lesions is an unusual and challenging condition that requires high preoperative diagnostic suspicion, considerate intraoperative judgment, and appropriate postoperative follow-up for successful outcomes. These tumors should be considered by the pediatric surgeons as possible PLP for recurrent intussusception, especially in older children. Surgeons should be familiar with the various treatment options, because the real cause of the intussusception is often accurately diagnosed by laparotomy. [ABSTRACT FROM AUTHOR]

The implementation of the Lean Six Sigma (LSS) in the textile and clothing industries is a successful strategy to reduce the defects produced along the production line in these industries. Lean Six Sigma readiness knowledge is a pre-requisite for a successful LSS implementation. Yet, the literature on Lean Six Sigma implementation and the readiness evaluation model in small and medium-sized textile and clothing are very limited. The purpose of this study is to develop a model of LSS readiness assessment for the clothing industries (LSRACI) using fuzzy logic. The present model is based largely on both the critical success factors (CSFs) of LSS and the LSS factors (enablers, criteria, and attributes) derived from the literature. The CSFs are identified using a questionnaire distributed to 85 small-medium clothing industries, and integration with the evaluation model. The outcome of this process is the identification of 5 enablers, 6 criteria, and 46 attributes which are finally ready to be used. The use of CSFs from the clothing industries gives a specification to our evaluation model and makes the LSRACI model original and specified to clothing SMEs. This model is developed for assessing the readiness level of the clothing and textile industries and it helps as well as to improve the readiness level for successful implementation of LSS. The present study aims to contribute to the knowledge of readiness for the LSS implementation in clothing industries. The readiness level of this company is average ready with (3.28; 4.9; 6.7). Using a fuzzy performance importance index (FPII), 20 from 46 attributes were identified as weaker attributes and therefore necessary corrective actions were recommended to improve the readiness level. The proposed model helps managers and practitioners to find out the potential of the clothing and textile industries by evaluating the company readiness before implementation in order to overcome problems and achieve a successful LSS implementation. [ABSTRACT FROM AUTHOR]

Background: Ganglioneuroma (GN) is an uncommon tumor belonging to the neuroblastic tumors group and is often localized in the posterior mediastinum, retroperitoneum, and adrenal gland. Presacral (PS) location is extremely rare. Its management remains a challenge. Case presentation: A 4-year-old child presented to our department for an isolated abdominal mass. Para-clinical exams concluded to PSGN. Subtotal surgical excision was performed through an anterior transperitoneal approach. The size of the residual tumor did not progress after the 6-year follow-up period and the patients were asymptomatic. Conclusions: GN should be considered in the case of soft tissue presacral masses in pediatrics. Subtotal resection seems sufficient in case of an extension to the sacrum with low morbidity. The residual tumors are still stable and the prognosis seems conserved. Further, long-term follow-up in large studies is needed to confirm these findings. [ABSTRACT FROM AUTHOR]

Background: Intestinal lipomas are benign, non-epithelial, intestinal tumors with an exceptionally rare localization at the ileum. Lipomas in the small intestine occur mainly in elderly patients and seldom occur in childhood. They are frequently asymptomatic, possibly due to their slow growth. These tumors may act as a lead point of intussusception. Case presentation: We report a rare case of double compounded ileo-ileal intussusception due to a submucosal intestinal lipoma in an 8-year-old female. To our knowledge, this is only the seventh pediatric case to be reported in the medical literature. Conclusions: Small intestinal submucosal lipoma should be considered in case of intussusception in pediatric patients. Surgical resection seems sufficient in case of symptomatic intestinal lipoma with low morbidity. [ABSTRACT FROM AUTHOR]

Copyright of Industria Textila is the property of Institutul National de Cercetare-Dezvoltare pentru Textile si Pielarie and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

• Hydatid disease is endemic in North Africa countries such as Tunisia. • Retroperitoneal location is scarce. • Parietal complications are rarely described even in endemic geographic locations. • Management of parietal complications of hydatid cysts is not consensual. • Surgical drainage remains the gold standard. Hydatid disease is a global zoonosis. Any organ of the human body can be involved. Single or multiple locations are reported. However, retroperitoneal hydatid cysts are uncommon. Furthermore, parietal complications are rarely reported in literature. Therefore, the management of hydatid cysts ruptured in the abdominal wall remains challenging. In this case report, we aim to describe our experience in treating a primary retroperitoneal hydatid cyst with rupture into abdominal wall in an 87-year-old woman who presented with a 15-centimeter mass of the right flank. Hydatid serology test was positive. An abdominal CT scan showed a 20-centimeter cystic mass of retroperitoneum extended to the abdominal wall with several septa within and enhanced thick wall. The patient underwent a surgical elective drainage with perioperative antiparasitic chemotherapy. Follow-up showed no recurrence. Primary retroperitoneal hydatid cyst with parietal complications is scarce and barely described in literature. We performed a review of the recent relevant literature that deals with this subject. None of the hydatid cysts reported in 55 cases was located in retroperitoneum. The top seven countries of origin are located in Mediterranean region except for India. Imaging is compulsory for the diagnosis along with patient's history, physical examination and hydatid serology. The treatment is surgical and must be must be covered by antiparasitic chemotherapy. Primary retroperitoneal hydatid cyst extended to the abdominal wall remains a rare and challenging diagnosis that must be considered in endemic countries. [ABSTRACT FROM AUTHOR]

Copyright of Industria Textila is the property of Institutul National de Cercetare-Dezvoltare pentru Textile si Pielarie and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Revue Francaise d'Allergologie is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Revue Francaise d'Allergologie is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Revue Francaise d'Allergologie is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Aspergillus flavus is the second leading cause of invasive and non-invasive aspergillosis. Secretion of hydrolytic enzymes is considered as a virulence factor in this species. Our work aimed to study in vitro production of some virulence factors, to evaluate the biofilm production against human and avian A. flavus isolates and to investigate the antifungal susceptibility agents. Hydrolytic enzymes, biofilm production and molecular typing were studied for 62 human and 36 avian A. flavus isolates by specific solid media and six microsatellite markers. The susceptibility to antifungal agents was evaluated for 37 human isolates. All human and avian A. flavus isolates showed positive activities of extracellular hydrolase: phospholipase, protease and hemolysin. A positive elastase activity was seen in 64.51% of human A. flavus isolates and 86.1% of avian A. flavus isolates. All A. flavus in these two populations formed biofilms. Statistical significant difference was observed for the mean phospholipase activities (P = 0.025) and biofilm quantification (P = 0.0001) between human and avian A. flavus isolates. The in vitro susceptibility results showed a resistance in 83.7%, 81.08% and 16.21% of A. flavus isolates respectively to amphotericin B, itraconazole and posaconazole. No association was noted between all virulence factors and the genotypes of human and avian isolates. Our study allowed us to show that human strains have a higher production of extracellular hydrolases and biofilm then avian strains. These virulence factors appear to act synergistically to contribute to the virulence of A. flavus strains. Moreover, significant correlation between virulence patterns and antifungal susceptibility profiles was observed. [ABSTRACT FROM AUTHOR]

Copyright of Industria Textila is the property of Institutul National de Cercetare-Dezvoltare pentru Textile si Pielarie and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Industria Textila is the property of Institutul National de Cercetare-Dezvoltare pentru Textile si Pielarie and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Abstract 1 1 Video demonstrations and a video presentation providing a summary of the paper can be found at https://goo.gl/EDvxhk. Low-cost Unmanned Aerial Vehicles (UAVs), also known as drones, are increasingly gaining interest for enabling novel commercial and civil Internet-of-Things (IoT) applications. However, there are still open challenges that restrain their real-world deployment. First, drones typically have limited wireless communication ranges with the ground stations preventing their control over large distances. Second, these low-cost aerial platforms have limited computation and energy resources preventing them from running heavy applications onboard. In this paper, we address this gap and we present Dronemap Planner (DP), a service-oriented cloud-based drone management system that controls, monitors and communicates with drones over the Internet. DP allows seamless communication with the drones over the Internet, which enables their control anywhere and anytime without restriction on distance. In addition, DP provides access to cloud computing resources for drones to offload heavy computations. It virtualizes the access to drones through Web services (SOAP and REST), schedules their missions, and promotes collaboration between drones. DP supports two communication protocols: (i.) the MAVLink protocol, which is a lightweight message marshaling protocol supported by commodities Ardupilot-based drones. (ii.) the ROSLink protocol, which is a communication protocol that we developed to integrate Robot Operating System (ROS)-enabled robots into the IoT. We present several applications and proof-of-concepts that were developed using DP. We demonstrate the effectiveness of DP through a performance evaluation study using a real drone for a real-time tracking application. [ABSTRACT FROM AUTHOR]

La bronchite plastique (BP) est caractérisée par la formation des moules épais ramifiés et fortement adhérents, qui obstruent partiellement ou complètement la lumière trachéobronchique. Elle constitue une complication évolutive d'affections respiratoires et/ou cardiaques préexistantes ou idiopathique qui se révèlent habituellement pendant l'enfance. Nous rapportons l'observation d'une femme, âgée de 48 ans, qui était admise pour exacerbation de son asthme. L'imagerie thoracique a objectivé la présence d'opacités parenchymateuses diffuses. L'exploration endoscopique de l'arbre trachéobronchique a montré l'obstruction étendue de l'arbre bronchique gauche par des moules bronchiques. L'évolution était favorable après l'ablation des moules intra bronchiques et le traitement par corticothérapie orale. La BP est une affection rare, généralement secondaire, une maladie respiratoire ou cardiaque chronique sous-jacente. Bien qu'habituellement de révélation précoce pendant l'enfance, la BP peut être diagnostiquée à l'âge adulte. Le traitement repose sur l'extraction des moules par voie endoscopique et sur le traitement de la pathologie sous jacente. Plastic bronchitis (PB) is characterized by the formation of thick branched and strongly adherent molds, which partially or completely obstruct the brachial lumen. It constitutes an evolutionary complication of preexisting or idiopathic respiratory and/or cardiac affections which usually appear during childhood. We report the case of a 48-year-old woman, who was admitted for exacerbation of her asthma. Chest imaging has shown the presence of diffuse parenchymal opacities. Endoscopic exploration of the tracheobronchial tree showed extensive obstruction of the left bronchial tree by bronchial molds. The evolution was favorable after removal of the intrabronchial molds and treatment with oral corticosteroid therapy. BP is a rare affection, usually secondary to an underlying chronic respiratory or heart disease. Although usually an early onset in childhood, BP can be diagnosed in adulthood. The treatment is based on the extraction of mules using the endoscope and on the treatment of the underlying pathology. [ABSTRACT FROM AUTHOR]

Résumé Introduction Le rôle du tabagisme actif et son impact sur l’asthme reste assez controversé. Objectif Déterminer la prévalence du tabagisme chez les asthmatiques adultes et évaluer son impact sur la maladie. Méthodes À partir d’un échantillon de 172 asthmatiques définis lors d’une enquête épidémiologique sur la prévalence de l’asthme dans une population représentative de la région du Grand Tunis, nous avons déterminé la prévalence du tabagisme et analysé les données relatives aux sujets tabagiques (G1) comparativement aux non tabagiques (G2). Les données ont été recueillies par un questionnaire « face to face » inspiré des études ISAAC et ECRHS. Le tabagisme a été évalué par autodéclaration. Le contrôle de l’asthme a été évalué selon le questionnaire asthma control test. Résultats L’âge moyen était de 33,5 ± 10 ans avec une prédominance féminine de 65,1 %. La prévalence du tabagisme actif était de 32 % avec un âge moyen de début à 22 ans. La prévalence des symptômes était comparable dans les 2 groupes en dehors du réveil par gêne respiratoire (72,7 % du G1 vs 53,8 % du G2). Seulement 14,5 % des asthmatiques prenaient actuellement leur traitement de fond : 3,6 % du G1 et 19,7 % du G2 ( p = 0,006). Selon l’ACT, 25,4 % avaient un asthme contrôlé : 50 % du G1 et 24,5 % du G2 ( p > 0,05). Conclusion Nos résultats rejoignent la plupart des données de la littérature avec un tabagisme actif élevé chez les asthmatiques. L’impact du tabagisme sur l’asthme reste discuté et les résultats semblaient assez contradictoires. Introduction Some controversy continues to surround the role of active smoking and its impact on asthma. Objectives To determine the prevalence of smoking among asthma patients and to assess its impact on the disease. Patients and methods From a sample of 172 asthmatic subjects, identified through an epidemiological survey of the Greater Tunis area, we analyzed the data of subjects who were active smokers (G1) vs. non-smoking asthmatics (G2). The data were collected using a “face-to-face” questionnaire inspired by the international ISAAC and ECRHS studies. Smoking was assessed by self-declaration. Asthma control was assessed using the Asthma Control Test questionnaire. Results The mean subject age was 33.5 ± 10 years, with female predominance (65.1%). Among our population, 32% were active smokers (G1) with an average consumption estimated at 17.3 PA. The average age on starting smoking was 22 years. The prevalence of symptoms was comparable in the two groups, aside from awakening due to respiratory discomfort (72.7% of G1 vs. 53.8% of G2). We noted that only 14.5% of asthmatics were currently taking their long-term treatment: 3.6% of G1 and 19.7% of G2 ( P = 0.006). According to the ACT, 25.4% of subjects had controlled asthma: 50% of G1 and 24.5% of G2 ( P > 0.05). Conclusion Active smoking was high among our subjects, and this is consistent with several studies. However, we found no evidence that asthmatics who smoke either exhibit more symptoms or have more severe asthma. The impact of cigarette smoking on asthma remains controversial and the results are fairly contradictory. [ABSTRACT FROM AUTHOR]