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Background: Three-dimensional weightbearing CT (WBCT) has been widely used to assess foot and ankle alignment. However, most current measurement methods are based on 2-dimensional concepts—distance, long axis, angulation, etc—and are sensitive to changes in orientation of the WBCT images. This study demonstrated how changes in positioning of the image can significantly influence the evaluation of hindfoot alignment. Methods: WBCT scans of 10 feet without deformities were used. In the horizontal view, the long axis of the foot image was aligned to a neutral position and then rotated 5, 10, 15, and 20 degrees both internally and externally to simulate malposition. The Calcaneal Moment Arm (CMA) was measured by 2 investigators independently in the above positions. An intraclass correlation coefficient (ICC) model was used to assess the intra- and interobserver reliabilities. The correlation between the CMA and the rotation angle of the foot images was analyzed using linear regression. Results: The CMA measurements demonstrated that internal rotation of the image changed the neutral hindfoot into valgus, whereas external rotation led to varus. A 1-degree internal or external rotation of the image correlated with 0.48 (±0.03) mm increase or decrease in the modified WBCT-CMA value (P <.0001, R 2 = 0.6406). Conclusion: This study demonstrated that although 3D WBCT provides the ability to observe the foot from different perspectives, current alignment evaluation tools are limited to 2 dimensions. Therefore, positioning the WBCT images in a consistent orientation is important to generate correct data. [ABSTRACT FROM AUTHOR]

Automated segmentation of 3-dimensional pulp space on cone-beam computed tomography images presents a significant opportunity for enhancing diagnosis, treatment planning, and clinical education in endodontics. The aim of this systematic review was to investigate the performance of artificial intelligence-driven automated pulp space segmentation on cone-beam computed tomography images. A comprehensive electronic search was performed using PubMed, Web of Science, and Cochrane databases, up until February 2024. Two independent reviewers participated in the selection of studies, data extraction, and evaluation of the included studies. Any disagreements were resolved by a third reviewer. The Quality Assessment of Diagnostic Accuracy Studies-2 tool was used to assess the risk of bias. Thirteen studies that met the eligibility criteria were included. Most studies demonstrated high accuracy in their respective segmentation methods, although there was some variation across different structures (pulp chamber, root canal) and tooth types (single-rooted, multirooted). Automated segmentation showed slightly superior performance for segmenting the pulp chamber compared to the root canal and single-rooted teeth compared to multi-rooted ones. Furthermore, the second mesiobuccal (MB2) canalsegmentation also demonstrated high performance. In terms of time efficiency, the minimum time required for segmentation was 13 seconds. Artificial intelligence-driven models demonstrated outstanding performance in pulp space segmentation. Nevertheless, these findings warrant careful interpretation, and their generalizability is limited due to the potential risk and low evidence level arising from inadequately detailed methodologies and inconsistent assessment techniques. In addition, there is room for further improvement, specifically for root canal segmentation and testing of artificial intelligence performance in artifact-induced images. [ABSTRACT FROM AUTHOR]

The Goutallier and Warner Classification systems are useful in determining rotator cuff reparability. Data are limited on how accurately the scapular-Y view used in both systems reflects the 3-dimensional (3-D) changes in fatty infiltration (FI) and muscle atrophy (MA). Tendon retraction in the setting of a cuff tear may also influence the perception of these changes. This study's objectives were to (1) measure the 3-D volume of the supraspinatus muscle in intact rotator cuffs, and with varying magnitudes of retraction; (2) measure the 3-D volume of FI in the supraspinatus muscle in these conditions; and (3) determine the influence of tendon retraction on measured FI and MA using the Goutallier and Warner Classification Systems. Between August 2015 and February 2016, all shoulder magnetic resonance images (MRIs) at the Portland VA Medical Center were standardized to include the medial scapular border. MRIs and charts were reviewed for inclusion/exclusion criteria. Included MRIs were categorized into 4 groups based on rotator cuff retraction. Supraspinatus muscle and fossa were traced to create 3-D volumes. FI and MA were measured within the supraspinatus. The supraspinatus muscle was graded among 6 physicians using the Goutallier and Warner classification systems. These grades were compared to 3-D measured FI and MA. The influence of tendon retraction on the measured grades were also evaluated. One hundred nine patients met inclusion/exclusion criteria. Ten MRIs for each group (N = 40) were included for image analysis. Supraspinatus volume tracings were highly reproducible and consistent between tracers. Supraspinatus muscle volumes decreased while global FI and MA increased with greater degrees of tendon retraction. In muscles with less than 10% global fat, fat concentrated in the lateral third of the muscle. In muscle with more than 10% global fat content, it distributed more diffusely throughout the muscle from medial to lateral. In comparing the scapular-Y to a medial cut, there was no consistent trend in FI whereas MA was more accurate at the medial cut. Parasagittal imaging location did not significantly influence the Goutallier score; however, assessment of MA using the Warner score leads readers to perceive less MA medially regardless of the magnitude of tendon retraction. The pattern of FI within the supraspinatus muscle changes from a laterally based location around the muscle-tendon junction to a more diffuse, global infiltration pattern when the whole muscle fat content exceeds 10%. [ABSTRACT FROM AUTHOR]

Variations in glenoid morphology affect surgical treatment and outcome of advanced glenohumeral osteoarthritis (OA). The purpose of this study was to assess the inter- and intraobserver reliability of the modified Walch classification using 3-dimensional (3D) computed tomography (CT) imaging in a multicenter research group. Deidentified preoperative CTs of patients with primary glenohumeral OA undergoing anatomic or reverse total shoulder arthroplasty (TSA) were reviewed with 3D imaging software by 23 experienced shoulder surgeons across 19 institutions. CTs were separated into 2 groups for review: group 1 (96 cases involving all modified Walch classification categories evaluated by 12 readers) and group 2 (98 cases involving posterior glenoid deformity categories [B2, B3, C1, C2] evaluated by 11 readers other than the first 12). Each case group was reviewed by the same set of readers 4 different times (with and without the glenoid vault model present), blindly and in random order. Inter- and intraobserver reliabilities were calculated to assess agreement (slight, fair, moderate, substantial, almost perfect) within groups and by modified Walch classification categories. Interobserver reliability showed fair to moderate agreement for both groups. Group 1 had a kappa of 0.43 (95% confidence interval [CI]: 0.38, 0.48) with the glenoid vault model absent and 0.41 (95% CI: 0.37, 0.46) with it present. Group 2 had a kappa of 0.38 (95% CI: 0.33, 0.43) with the glenoid vault model absent and 0.37 (95% CI: 0.32, 0.43) with it present. Intraobserver reliability showed substantial agreement for group 1 with (0.63, range 0.47-0.71) and without (0.61, range 0.52-0.69) the glenoid vault model present. For group 2, intraobserver reliability showed moderate agreement with the glenoid vault model absent (0.51, range 0.30-0.72), which improved to substantial agreement with the glenoid vault model present (0.61, range 0.34-0.87). Inter- and intraobserver reliability of the modified Walch classification were fair to moderate and moderate to substantial, respectively, using standardized 3D CT imaging analysis in a large multicenter study. The findings potentially suggest that cases with a spectrum of posterior glenoid bone loss and/or dysplasia can be harder to distinguish by modified Walch type because of a lack of defined thresholds, and the glenoid vault model may be beneficial in determining Walch type in certain scenarios. The ability to reproducibly separate patients into groups based on preoperative pathology, including Walch type, is important for future studies to accurately evaluate postoperative outcomes in TSA patient cohorts. [ABSTRACT FROM AUTHOR]

Rationale and Objectives: This study uses a three-dimensional energy Doppler technique combined with the Virtual Organ Computer-aided Analysis (VOCAL) method in order to determine the diagnostic threshold of blood flow index in breast tumors to provide a reference for evaluation and treatment options.Materials and Methods: We collected 322 solid lesions which had been operated. Each lesion met the definite pathological diagnosis; collected lesions included 262 cases of benign lesions and 60 cases of malignant lesions. All examinations were performed by using GE LOGIQ E9 with VOCAL software. Volume and four distinct vascular indices of gray mean (MG), power mean, ratio (R), and vascular flow index (VFI) were calculated by using the VOCAL software. Sampling and calculation were repeated three times and the mean value was calculated.Results: The average age and power of the malignant group were greater than those of the benign group, ie p < .01 which had significant differences. The gray mean of the malignant group was lower than that of the benign group, ie p > .05 which had no significant differences between benign and malignant groups. The ratio, vascular flow index and volume had significant differences, i.e. p < .01. The area under the receiver operating characteristic curve (AUC) were 0.864, 0.830, 0.800, 0.758, and 0.764 for age, power, ratio, vascular flow index, and volume, respectively. The research indicators were higher than 50% of the curve showing their diagnostic value. The cut-off points of age, power, ratio, vascular flow index, and volume were 37.5, 26.56, 0.031, 0.846, and 1.75, respectively. Their corresponding sensitivity were 93.3%, 75%, 81.7%, 68.3%, 63.3%, and the specificity were 68.7%, 81%, 70.2%, 75.6%, and 81.7%, respectively. Comparison of vascular indices combined with the Breast imaging reporting and data System (BI-RADS) score and simple BI-RADS method, the AUC of power + BI-RADS, ratio + BI-RADS, VFI + BI-RADS, and BI-RADS alone are 0.928, 0.903, 0.895, and 0.796, respectively, which were higher than 50% of the curve. Sensitivity was 81.7%, 80%, 88.3%, 86.7%, and specificity was 88.5%, 85.5%, 77.1%, 69.5%, respectively. The power + BI-RADS method has the highest AUC among these three methods.Conclusions: Quantitative measurement of blood flow and blood vessel distribution in breast tumors by three-dimensional power Doppler ultrasound combined with the VOCAL method is more accurate and sensitive than the traditional two-dimensional ultrasound. And this method has potential promising applications in many current active research areas, such as the studies of random distribution of intratumoral blood vessels or the normalization of tumor blood vessels. Three-dimensional power Doppler ultrasound combined with the VOCAL method provides a new approach to achieving accurate judgments and the method evaluates the curative effect in breast cancer patients. [ABSTRACT FROM AUTHOR]

When treating posterolateral rotatory instability, the lateral ulnar collateral ligament (LUCL) is more commonly reconstructed than the other dynamic stabilizer structures. Although numerous surgical techniques have been described for LUCL reconstruction, studies have been limited to static analyses of single-strand reconstructions. The aim of this study was to dynamically analyze the kinematics of double-strand LUCL reconstructions with 3 different configurations of graft placement: horizontal, vertical, and triangular. Five healthy elbow joints with no signs of pre-existing pathology were scanned by computed tomography, and the images were converted into 3-dimensional models. The humeral origin and ulnar insertions of the 2 ligament strands were registered in 3-matic software for the 3 graft placement configurations. A dynamic elbow joint was simulated at 1° increments throughout the motion arc. The ligament strand lengths and the difference between them were measured. The ligament lengths for each strand for the 3 graft configurations were as follows: horizontal, 31.0 ± 4.6 mm and 34.3 ± 5.0 mm; vertical, 32.5 ± 3.6 mm and 35.4 ± 4.2 mm; and triangular, 32.0 ± 4.0 mm and 33.7 ± 3.1 mm. The minimum length differences for the graft strands through the motion arc for the horizontal, vertical, and triangular graft configurations were 1.1, 0.0, and 1.0 mm, respectively. Dynamic analyses using a 3-dimensional elbow model showed that none of the configurations for double-strand LUCL reconstruction were isometric. However, the vertical double-strand configuration was nearly isometric and may therefore serve as a coequal option. [ABSTRACT FROM AUTHOR]

In daily echocardiographic practice, the right ventricle (RV) is assessed using mostly 2-dimensional (2D) echocardiography. Parameters measuring longitudinal shortening (eg, tricuspid annular plane systolic excursion) or changes in areas (eg, fractional area change) are used as surrogates for right ventricular function. Three-dimensional (3D) echocardiography–based techniques allow for cardiac magnetic resonance imaging–validated assessment of the RV. Depiction of regional right ventricular function is of increasing clinical interest. This study aimed to calculate regional volumetric changes in the right ventricular inlet, apical section, and outflow tract. Correlations between traditional parameters and regional right ventricular function were studied. Retrospective cohort study on patients scheduled for cardiac surgery. Tertiary care university hospital. The study comprised 80 patients scheduled for cardiac surgery. Based on 3D echocardiographic datasets, mesh models of the RV were generated on a vendor-independent platform. The meshes were further cut into the following 3 regions: the inlet part, the apical section, and the outflow tract. The regional volumes and ejection fractions were compared with the global right ventricular and left ventricular functions. Regional volumes were correlated linearly with the global end-diastolic volume. The right ventricular outflow tract demonstrated a significantly lower ejection fraction than the inlet part (34% ± 11% v 28% ± 11%; p = 0.0054). The function in the right ventricular outflow tract was reduced significantly compared with the global right ventricular function in patients with severely reduced left ventricular ejection fraction (<20%). The different parts of the RV seem to have different ejection fractions. Different regions of the RV are affected differently by reduced left ventricular ejection fraction. Regional right ventricular analyses could help clinicians better understand pathologic states of the RV. [ABSTRACT FROM AUTHOR]

Abstract Hoof conformation has been linked to catastrophic musculoskeletal injuries. Previous studies have been focused on two-dimensional measurements, thus existing knowledge on three-dimensional hoof analysis is very limited. The objective of this study was to examine the morphogeometric properties of the equine hoof using magnetic resonance imaging technology and provide a benchmark for volumetric internal and external anatomy of the hoof and to investigate the correlation between those measurements. Eighteen horses (5.8 ± 2.6 years) with no known hoof pathologies had undergone magnetic resonance imaging; transverse and mid-sagittal (T1-weighted) images were analyzed. Calibrated digital conformational pictures were also taken. In total, 14 internal and 18 external anatomy measurements were performed using Image J software. Patterns of pairwise correlations were found, that is, the distal phalanx volume was correlated with its width (r = 0.739), but not its length. Digital cushion volume was correlated with its length (r = 0.802). Navicular bone width was correlated with distal phalanx width (r = 0.710), but not deep digital flexor tendon width (r = 0.541). The distal phalanx volume and total hoof volume were correlated with the weight of the horse. Our results provide valuable linear and volumetric data for three-dimensional hoof anatomy and provide valuable information for clinicians and researchers to better identify internal hoof anatomy and differentiate pathological cases. Highlights • Volumetric measurement of healthy equine hoof. • Conformational measurements of the healthy hoof. • Hoof of Standardbred horses without clinical lameness or abnormalities. • Benchmark to characterize morphometric range of a healthy hoof. [ABSTRACT FROM AUTHOR]

Purpose: To assess interobserver variation and efficiency of various measurements on 3-dimensional transvaginal ultrasound (3DTVS) and saline infusion sonography (3D-SIS) for preoperative measurement of deep myometrial invasion (DMI) in endometrial cancer. Materials and Methods: One hundred ten women with atypical endometrial hyperplasia or endometrial adenocarcinoma had preoperative 3D-TVS and 3D-SIS. Endometrial thickness (ET), ET in percent of uterine diameter (PAP) and various volumes were measured. AUC, sensitivity, and specificity of most optimal cut-points, and kappa statistics for observer variation were calculated. Results: PAP identified two-thirds of women with DMI. ET and 3D volume measurements had substantial observer agreement compared to moderate agreement of subjective evaluation of DMI. AUC for measurements ranged 0.63-0.73 for identification of DMI. Subjective evaluation of DMI had highest AUC only marginally improved by adding PAP. Conclusion: Preoperative staging of endometrial cancer is not improved by adding 3D volume measurements to subjective evaluation, but PAP could be used to select women with a high risk of DMI for further MRI. [ABSTRACT FROM AUTHOR]

One of the most common procedures performed in the foot and ankle is correction of hallux abducto valgus deformity or “bunion surgery.” Most foot and ankle surgeons recognize the challenges associated with defining each patient's individual deformity and selecting the optimal procedure for the best long-term results. Using current 2-dimensional algorithms that focus on the severity of the transverse plane deformity, surgical outcomes have varied. In the past 10 years, high recurrence and complication rates for popular procedures have been reported. In the same period, the reported data have elucidated an evolving anatomic understanding of the bunion deformity, with an expansion to 3 dimensions, including the frontal/coronal plane. We present a new classification and approach for the evaluation and procedure selection for bunion surgery. We hope this conceptual treatise on hallux abducto valgus based on clinical consensus and current data will stimulate academic discussion and further research. This anatomic classification is based on the 3-dimensional anatomy of the first ray. [ABSTRACT FROM AUTHOR]

Background The goals of this study were to evaluate the reliability of a quantitative 3-dimensional computed tomography (Q3DCT) technique for measurement of the capitellar osteochondritis dissecans (OCD) surface area, to analyze OCD distribution using a mapping technique, and to investigate associations between Q3DCT lesion quantification and demographic characteristics and/or clinical examination findings. Methods We identified patients with capitellar OCD who presented to our orthopedic sports medicine practice between January 2001 and January 2016 and who had undergone a preoperative computed tomography scan (slice thickness ≤1.25 mm). A total of 17 patients with a median age of 15 years (range, 12-23 years) were included in this study. Three-dimensional polygon models were reconstructed after osseous structures were marked in 3 planes. Surface areas of the OCD lesion as well as the capitellum were measured. Observer agreement was assessed with the intraclass correlation coefficient (ICC). Heat maps were created to visualize OCD distribution. Results Measurements of the OCD surface area showed almost perfect intraobserver agreement (ICC, 0.99; confidence interval [CI], 0.98-0.99) and interobserver agreement (ICC, 0.93; CI, 0.86-0.97). Measurements of the capitellar surface area also showed almost perfect intraobserver agreement (ICC, 0.97;CI, 0.91-0.99) and interobserver agreement (ICC, 0.86; CI, 0.46-0.96). The median OCD surface area was 101 mm 2 (range, 49-217 mm 2 ). On the basis of OCD heat mapping, the posterolateral zone of the capitellum was most frequently affected. OCDs in which the lateral wall was involved were associated with larger lesion size ( P  = .041), longer duration of symptoms ( P  = .030), and worse elbow extension ( P  = .013). Conclusions The ability to quantify the capitellar OCD surface area and lesion location in a reliable manner using Q3DCT and a mapping technique should be considered when detailed knowledge of lesion size and location is desired. [ABSTRACT FROM AUTHOR]

The aim of this prospective study was to correlate the postoperative 3-dimensional facial changes in skeletal class III deformity with sagittal jaw movements in 84 patients who had been treated by one piece Le Fort I maxillary advancement only (n = 18), mandibular setback only (n = 38), or both procedures (n = 28). At the times of evaluation before and six months after operation all patients had fixed orthodontic appliances. Soft tissue changes were evaluated on optical 3-dimensional scans, while lateral cephalograms were superimposed to assess sagittal jaw movements. Three-dimensional surface facial scans were divided into 11 regions. We modelled soft tissue changes in each region by linear regression with maxillary (point A) and mandibular (point B) sagittal movements as predictors, and adjusted for sex, age, body mass index, type of operation, and interincisal angle. We found the highest values of regression coefficients (around 0.5) for the sagittal movements of the variables points A and B within the regions of the upper and lower lips. This meant that for each mm of maxillary advancement and mandibular setback, the soft tissue moved 0.5 mm. In the sides of the face the regression coefficients were between 0.1 and 0.3, as were those within regions indirectly affected by the operations. [ABSTRACT FROM AUTHOR]

The serpentine flow channel can be considered as one of the most common and practical channel layouts for a polymer electrolyte membrane fuel cell (PEMFC) since it ensures an effective and efficient removal of water produced in a cell with acceptable parasitic load. Water management is one of the key issues to improve the cell performance since at low operating temperatures in PEMFC, water vapor condensation starts easily and accumulates the liquid water droplet within the flow channels, thus affecting the chemical reactions and reducing the fuel cell performance. In this article, a comprehensive three dimensional numerical simulation is carried out to understand the water droplet mobility in a serpentine gas flow channel for a wide range of surface properties, inlet air velocities, droplet positions (center or off-center, bottom or top) and droplet sizes by deploying a finite volume based methodology. The liquid-gas interface is tracked following the volume-of-fluid (VOF) method. The droplet transport is found to be greatly influenced by the surface wettability properties, inlet velocities, number of droplets emerged and initial droplet positions. Super hydrophobic surface property is not always preferable for designing the gas flow channels. It depends upon the inlet velocity conditions, droplet positions, number of droplets and surface properties. [ABSTRACT FROM AUTHOR]

Objective: To describe studies evaluating 3 generations of three-dimensional (3D) displays over the course of 20 years. Summary Background Data: Most previous studies have analyzed performance differences during 3D and two-dimensional (2D) laparoscopy without using appropriate controls that equated conditions in all respects except for 3D or 2D viewing. Methods: Databases search consisted of MEDLINE and PubMed. The reference lists for all relevant articles were also reviewed for additional articles. The search strategy employed the use of keywords "3D," "Laparo-scopic," "Laparoscopy," "Performance," "Education," "Learning," and "Surgery" in appropriate combinations. Results: Our current understanding of the performance metrics between 3D and 2D laparoscopy is mostly from the research with flawed study designs. This review has been written in a qualitative style to explain in detail how prior research has underestimated the potential benefit of 3D displays and the improvements that must be made in future experiments comparing 3D and 2D displays to better determine any advantage of using one display or the other. Conclusions: Individual laparoscopic performance in 3D may be affected by a multitude of factors. It is crucial for studies to measure participant stereoscopic ability, control for system crosstalk, and use validated measures of performance. [ABSTRACT FROM AUTHOR]

Aim We report our experience with the use of 1.7 mm 3-dimentional (3D) strut plate for the management of mandibular angle fractures. Methods This prospective study enrolled 15 patients in whom mandibular angle fractures were treated with 1.7 mm 3D plate using trans-buccal trochar. Patients were evaluated at 72 h, 2 weeks, 6 weeks and 12 weeks for fracture stability, occlusion, soft-tissue swelling, infection and post-operative inferior alveolar nerve damage. Other complications like wound dehiscence, non-union, mal-union and hardware failure were also assessed. Results In the immediate post-operative period, fracture instability was seen in 1 (6.7%) patient which resolved by 2 weeks. Mild occlusal discrepancy was also noted in 1 (6.7%) patient. Wound dehiscence was seen in 5 (33.3%) patients and all resolved by local measures. 1 (6.7%) patient developed post-operative nerve paraesthesia. Immediate post-operative radiographic evaluation demonstrated optimal reduction in all cases with no inferior border gaping. No case of infection, hardware failure, non-union and mal-union was noted. Conclusion Within the limitations of the study, 1.7 mm 3D strut plate was found to be effective for management of non-communited mandibular angle fractures. [ABSTRACT FROM AUTHOR]

Purpose To determine whether distal radioulnar joint (DRUJ) contact characteristics were altered in patients with malunited distal radius fractures. Methods We obtained computed tomography scans at 5 positions of both wrists of 6 patients who had unilateral malunited distal radius fractures with dorsal angulation from 10° to 20° and ulnar variance less than 3 mm. We reconstructed 3-dimensional images and mapped contact regions of DRUJ by calculating the shortest distance between the 2 opposing bones. The contact areas of the DRUJ were measured and the contact region centers were calculated and analyzed. The values of the malunited side were compared with those of the contralateral uninjured side. Results In the uninjured wrist, the contact areas of the DRUJ increased slightly from wrist flexion to extension and ulnar deviation. In the malunited wrist, we found the contact areas of DRUJ to be progressively reduced from 20° flexion to neutral, 40° extension, and 20° extension, to ulnar deviation. The centroid of this area on the sigmoid notch moved to distal from flexion to extension. Compared with the contralateral uninjured wrist, the contact area significantly decreased during wrist extension and ulnar deviation, and significantly increased during wrist flexion. The centroids of this area on sigmoid notch all moved volarly in all selected wrist positions. Conclusions The contact areas of the DRUJ and the centroid of contact area on sigmoid notch are altered in patients with malunited distal radius fractures. The contact area of the DRUJ increases during wrist flexion and decreases during wrist extension and ulnar deviation. The centroids of the contact area on sigmoid notch move volarly during wrist flexion-extension and ulnar deviation. Clinical relevance The in vivo findings suggest that alterations in joint mechanics may have an important role in the dysfunction associated with these injuries. [ABSTRACT FROM AUTHOR]

Purpose The present study aims to determine any existing association between airway dimensions, measured with cone beam computed tomography (CBCT), and the different patient craniofacial morphologies. Material and methods Sixty CBCT (Dental Picasso Master 3D) images, from patients treated at the Orthodontics Master at Valencia University were selected. The program InVivoDental 5.1 was used to visualize sections, analyze three-dimensional images, and perform airway measurements in the three planes of the space. Intra- and interobserver error methods were recorded. After that, measurements at three different levels of the airway (upper, medium, lower) were taken, in both the anteroposterior and transversal directions of the airway space. The area (mm 2 ) of the airway space at the three levels was also measured. Results In the anteroposterior airway measurements, there were differences between the measurements by level. The magnitude of these differences depended on the skeletal pattern of the individual. In the transversal airway measurements and in the area airway measurements, there were no differences according to the skeletal pattern. However, in the transversal direction, measurements in the lower level were significantly higher than in the superior level in all cases. When measuring the area, significantly higher measurements in the upper level were recorded. The homogeneity between medium and lower levels decreased gradually from class I to class III subjects. Conclusions No statistically significant results were observed that related the anteroposterior and vertical skeletal craniofacial morphology with airway dimensions, although some specific associations have been detected for certain airway levels or for pattern combinations. [ABSTRACT FROM AUTHOR]

Background The purpose of this study was to define the relationship between the humeral neck-shaft angle (NSA) and variations in the ideal entry portal aligned with the long axis of the intramedullary canal of the proximal humerus. Methods Three-dimensional images of 36 cadaveric humeri with various NSAs were reconstructed by a computerized surgical simulation program. The anteroposterior, mediolateral, and linear distances between a line from the center of the proximal medullary canal to the bicipital groove were measured. Differences among humeri with various NSAs were analyzed. Results The intramedullary axis line was located a mean of 9 ± 2 mm posteriorly and 11 ± 3 mm medially from the bicipital groove. The axis line was 9 ± 2 mm posterior and 11 ± 2 mm medial with a standard NSA. The axis line in humeri with a varus NSA was 8 ± 2 mm posteriorly and 9 ± 2 mm medially, whereas the axis line was 10 ± 3 mm posteriorly and 14 ± 3 mm medially with a valgus NSA. The differences in the mediolateral distances between the groups were significant ( P < .00009). Conclusion Care should be taken in choosing the entry portal position in humeri with various NSAs as the entry portal position differs according to the NSA. It is recommended that the location of the entry portal be moved toward the center of the humeral head to align with the centerline of the intramedullary canal in humeri with a valgus NSA in particular. [ABSTRACT FROM AUTHOR]

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Background The presence of complex fractionated atrial electrograms (CFAEs) and high dominant frequencies (DFs) during atrial fibrillation (AF) have been demonstrated to be related to AF maintenance. Therefore, sequential mapping of CFAEs and DFs have been used for target sites of AF ablation. However, such mapping strategies are valid only if the CFAEs and DFs are spatiotemporally stable during the mapping procedure. We obtained spatially stable multi-electrode recordings to assess the spatiotemporal stability of CFAEs and DFs. Methods We recorded electrical activity during AF for 10 min with a 64-electrode basket catheter (48 bipole electrode pairs) placed in the left atrium in 36 patients with AF (paroxysmal AF [PAF], n =16; persistent AF [PerAF], n =20). The spatial and temporal distribution of the CFAEs (fractionation interval <120 ms) and high DFs (>8 Hz) at 1-min intervals for 10 min were compared for each of the 48 bipoles. Results The baseline CFAEs were located at 68.5±14.0% (32.9±6.7) of the 48 bipoles; however, the high DF sites were fewer (9.6±8.6% [4.6±4.1 bipoles]). The CFAEs sites did not change significantly during the 10-min recording period (kappa statistic: 0.71±0.24); however, the high DF sites changed significantly (kappa statistic: 0.07±0.19). These spatiotemporal changes in the CFAEs and high DFs did not differ between patients with PAF and PerAF. Conclusions Regardless of the AF type, CFAEs sites, but not high DF sites, showed a high degree of spatial and temporal stability. [ABSTRACT FROM AUTHOR]

Purpose Using quantitative 3-dimensional computed tomography (Q3DCT) modeling, we tested the null hypothesis that there was no difference in fracture fragment volume, articular surface involvement, and number of fracture fragments between coronoid fracture types and patterns of traumatic elbow instability. Methods We studied 82 patients with a computed tomography scan of a coronoid fracture using Q3DCT modeling. Fracture fragments were identified and fragment volume and articular surface involvement were measured within fracture types and injury patterns. Kruskal–Wallis test was used to evaluate the Q3DCT data of the coronoid fractures. Results Fractures of the coronoid tip (n = 45) were less fragmented and had the smallest fragment volume and articular surface area involvement compared with anteromedial facet fractures (n = 20) and base fractures (n = 17). Anteromedial facet and base fractures were more fragmented than tip fractures, and base fractures had the largest fragment volume and articular surface area involvement compared with tip and anteromedial facet fractures. We found similar differences between fracture types described by Regan and Morrey. Furthermore, fractures associated with terrible triad fracture dislocation (n = 42) had the smallest fragment volume, and fractures associated with olecranon fracture dislocations (n = 17) had the largest fragment volume and articular surface area involvement compared with the other injury patterns. Conclusions Analyzing fractures of the coronoid using Q3DCT modeling demonstrated that fracture fragment characteristics differ significantly between fracture types and injury patterns. Detailed knowledge of fracture characteristics and their association with specific patterns of traumatic elbow instability may assist decision making and preoperative planning. Clinical relevance Quantitative 3DCT modeling can provide a more detailed understanding of fracture morphology, which might guide decision making and implant development. [ABSTRACT FROM AUTHOR]

Introduction Two-dimensional laparoscopy for living donor nephrectomy is the current standard of care. We report the first case of three-dimensional laparoscopy for living-donor nephrectomy with vaginal extraction. Presentation of case The procedure was performed in a 66-year-old woman donating his left kidney to her son with the HD S 3D column (Karl Storz, Tuttlingen, Germany). Preoperative computed tomography showed one left renal artery. The warm ischemic time was 2 min 20 s and the operative time was 200 min. There was no loss of blood and no intraoperative or postoperative complications. Discussion This report demonstrates the feasibility of using 3D laparoscopy which allows for a more in-depth vision, greater overall definition of planes, better accuracy of dissection and reduced operative times, for nephrectomy with vaginal extraction for kidney donation. Conclusion Three-dimensional laparoscopy for living-donor nephrectomy with vaginal extraction is feasible and could become a new standard. [ABSTRACT FROM AUTHOR]

Introduction: This study presents a method to verify the position of dental implants after insertion without the repeated x-ray exposure. Material and Methods: An implant was inserted into the natural gap between the canines and premolars of 8 domestic pigs and 1 human patient. A scanbody was then connected to the implants and a digital intraoral impression of the jaw segment was acquired using a handheld scanner. In addition, the implant position was radiologically detected by cone beam computed tomography. The position of the implant based on both techniques was compared by digital matching. Results: The position of the dental implants determined by the scanner accurately represents the position in the radiograph in the pigs and also in the human patient. Conclusion: Evaluating the position of implants using intraoral scans is a straightforward, accurate, and radiation-free method of 3-dimensional implant position determination. [ABSTRACT FROM AUTHOR]

Background Due to the lack of studies, we evaluated the validity and reliability of multirooted tooth measurements derived from cone-beam computed tomography (CBCT) and periapical (PA) radiography. Methods CBCT scans and PA radiographs were obtained from 16 patients (30 and 18 maxillary molars and premolars, respectively, were evaluated). The CBCT scans were taken at 0.4 mm voxel size. Using X, Y, and Z coordinates, the cusp tips and root apices were used to calculate two tooth lengths and two root lengths of the premolars, and three tooth lengths and three root lengths of the molars. PA radiographs were taken from the same patients at the same time. The same tooth and root lengths were measured. Results There were no systematic differences between replicates. Systematic errors ranged from 0.001 to 0.119 mm (premolars) and from 0.001 to 0.052 mm (molars). Only buccal premolar root lengths, as measured on the PA radiographs, and buccal molar root lengths, as measured on the CBCT images, showed statistically significant differences ( P < 0.05). Random method errors ranged from 0.11 to 0.22 mm with CBCT and from 0.06 to 0.14 mm with PA radiography. PA radiography significantly underestimated root length and overestimated molar tooth length. Conclusions Although both methods are reliable, greater random errors were associated with the CBCT than with PA measurements. PA radiography underestimated buccal lengths and overestimated lingual tooth lengths of the premolars and molars, respectively. [ABSTRACT FROM AUTHOR]

Abstract: The hammer throw in athletics has been the subject of published research since the 1980s. This has focused on case studies of individual athletes or small cohorts and has identified a number of key performance indicators such as the speed profile of the hammer during the wind-up phase. To use these key performance indicators with current athletes a bespoke analysis tool is required for frequent data collection. An unobtrusive two cameras system was proposed and a non-standard planar calibration method that allows the safety cage to remain in place was designed. The performance of the non-standard calibration method was compared to the standard calibration method using simulated data. The non-standard method was found to be suitable when intrinsic camera parameters were not recomputed. The method is a suitable alternative for volumes that cannot easily be accessed with a calibration object or volumes that are too large for practically sized calibration objects [Copyright &y& Elsevier]

Background: Concerns regarding insufficient press fit and glenoid vault cortical blowout make glenoid osteochondral allografting uncommon. We used 3-dimensional computed tomography modeling to test glenoid osteochondral allografting feasibility. Materials and methods: Sixteen cadaveric shoulders without osteoarthritis underwent computed tomography scans to create 3-dimensional models. The diameter of circular center-based reaming reaching the medial endosteal surface at depths of 4, 6, and 8 mm and the clock face position of the most shallow points were calculated. Demographic factors associated with graft diameter were analyzed by step-wise multiple regressions. Results: Shallower graft depths allowed larger graft diameters (P < .001). With a graft depth of 4 mm, 56% of glenoids allowed 20-mm-diameter grafts and 94% accommodated 16-mm grafts versus 31% and 75%, respectively, for a graft depth of 6 mm and 13% and 38%, respectively, for a graft depth of 8 mm. Increasing graft depth decreased graft glenoid coverage: mean coverage was 51.9% ± 12.2%, 36.3% ± 12.9%, and 23.8% ± 14.2% for 4-, 6-, and 8-mm depths, respectively. The glenoid's most shallow point was between the 1:30 clock face position and 3-o'clock position in reference to a right shoulder in 69%, 75%, and 44% of glenoids for 4-, 6-, and 8-mm depths, respectively. Although female gender, patient height, and glenoid height and width were associated with graft diameter, multiple regression analysis showed that patient height was the only independent variable associated with accommodated graft diameter at depths of 4, 6, and 8 mm (P = .001, P = .001, and P = .003, respectively). Conclusion: Most glenoids support center-based grafts of 16 to 20 mm in diameter at a depth of 4 mm, covering an average of 51.9% of the glenoid. Accommodated graft size decreases as reaming depth increases. [Copyright &y& Elsevier]

Objectives: This study sought to investigate the impact of left main coronary artery (LMCA) 3-dimensional (3D) bifurcation angle (BA) parameters on 5-year clinical outcomes of patients randomized to LMCA percutaneous coronary intervention (PCI) in the SYNTAX (Synergy Between Percutaneous Coronary Intervention With Taxus and Cardiac Surgery) trial. Background: BA can affect outcome after bifurcation PCI; 3D angiographic analysis provides reliable BA measurements. Methods: The diastolic distal BA (between left anterior descending and left circumflex) and its systolic-diastolic range were explored. A stratified post-hoc survival analysis was performed for 5-year major adverse cardiac and cardiovascular events (MACCE) (all-cause death, cerebrovascular accident, myocardial infarction, or repeat revascularization), a safety endpoint (all-cause death, cerebrovascular accident, or myocardial infarction), and repeat revascularization. Analysis was performed in patients where 3D BA was available pre- and post-PCI. Results: Of 266 patients eligible for analysis, 185 underwent bifurcation PCI (group B); 1 stent was used in 75 patients (group B1), whereas ≥2 stents were used in 110 patients (group B2). Stratification across pre-PCI diastolic distal BA tertiles (<82°, 82° to 106°, ≥107°) failed to show any difference in MACCE rates either in the entire study population (p = 0.99) or in group B patients (p = 0.78). Group B patients with post-PCI systolic-diastolic range <10° had significantly higher MACCE rates (50.8% vs. 22.7%, p < 0.001); repeat revascularization and safety endpoint rates were also higher (37.4% vs. 15.5%, p = 0.002, and 25.4% vs. 14.1%, p=0.055, respectively). Post-PCI systolic-diastolic range <10° was an independent predictor of MACCE (hazard ratio: 2.65; 95% confidence interval: 1.55 to 4.52; p < 0.001) in group B patients. Conclusions: A restricted post-procedural systolic-diastolic distal BA range resulted in higher 5-year adverse event rates after LMCA bifurcation PCI. Pre-PCI BA value did not affect the clinical outcome. [Copyright &y& Elsevier]

Purpose: The purpose of this study was to compare four graft-tunnel angles (GTA), the femoral GTA formed by three different femoral tunneling techniques (the outside-in, a modified inside-out technique in the posterior sag position with knee hyperflexion, and the conventional inside-out technique) and the tibia GTA in 3-dimensional (3D) knee flexion models, as well as to examine the influence of femoral tunneling techniques on the contact pressure between the intra-articular aperture of the femoral tunnel and the graft. Materials and Methods: Twelve cadaveric knees were tested. Computed tomography scans were performed at different knee flexion angles (0°, 45°, 90°, and 120°). Femoral and tibial GTAs were measured at different knee flexion angles on the 3D knee models. Using pressure sensitive films, stress on the graft of the angulation of the femoral tunnel aperture was measured in posterior cruciate ligament reconstructed cadaveric knees. Results: Between 45° and 120° of knee flexion, there were no significant differences between the outside-in and modified inside-out techniques. However, the femoral GTA for the conventional inside-out technique was significantly less than that for the other two techniques (p<0.001). In cadaveric experiments using pressure-sensitive film, the maximum contact pressure for the modified inside-out and outside-in technique was significantly lower than that for the conventional inside-out technique (p=0.024 and p=0.017). Conclusion: The conventional inside-out technique results in a significantly lesser GTA and higher stress at the intra-articular aperture of the femoral tunnel than the outside-in technique. However, the results for the modified inside-out technique are similar to those for the outside-in technique. [ABSTRACT FROM AUTHOR]

The article reports on research which was conducted to assess the three dimensional anatomy of the Lisfranc ligament and its attachment sites. Researchers evaluated 37 cadaver feet that were dissected to expose the ligament attachments at the Lisfranc joint.They found that the Lisfranc ligament is variable in anatomy and can have a single or double-bundle arrangement and that its area of attachment is larger than that of the plantar ligament.

Background: Idiopathic left ventricular tachycardia (ILVT) is a common form of ventricular tachycardia (VT) in structurally normal heart. Different methods have been proposed for radiofrequency ablation (RFA) of ILVT that have good short-term results but recurrence is higher. Termination of tachycardia during RFA and/or noninduciblity has been the procedural end point. Objective: To describe electrophysiological markers that add to long-term freedom from recurrences. Methods: Fifteen patients with ILVT underwent RFA guided by 3-dimensional electroanatomical mapping. After creating a 3-dimensional geometry of the left ventricle (LV), the conduction system of the LV was mapped by tracing from His recording from the left ventricular outflow tract and distally till the fascicles and perifascicular myocardium. VT was induced by using programmed electrical stimulation. Ablation was done targeting the distal posterior fascicle and extended linearly to the surrounding myocardium till conduction block was achieved between the fascicle-Purkinje network and the left ventricular myocardium. Results: All patients (13 men; mean age 32±9 years) had inducible VTs. The mean tachycardia cycle length was 320±28 ms. Radiofrequency energy was given to the distal posterior fascicle and the myocardium, with an aim to achieve a myocardial-fascicular conduction block in addition to the termination of VT and noninducibility. Ablation was successful in all. No recurrence of tachycardia was seen in any patient on follow-up (20.8±8.5 months). Conclusions: Distal posterior fascicle and Purkinje-myocardial junction is an effective target site for ILVT ablation. The demonstration of myocardial to fascicle conduction block serves as an important electrophysiological marker of successful ablation and improved long-term success. [Copyright &y& Elsevier]

Purpose: The purpose of this review was to evaluate new computer software available for 3-dimensional right ventricular (RV) volume estimation. Description: Based on 2-dimensional echocardiography, various algorithms have been used for RV volume estimation. These are complex, time-consuming techniques and are prone to significant error. The current clinical paradigm of RV volume assessment is based on the visual quantitative assessment of chamber size and the use of tricuspid annular and RV internal diameters as a surrogate measure of RV volume. Hence, there is a need for a practical method for the intraoperative assessment of RV volume. Evaluation: The evaluation consists of an objective review of the capabilities of this software and its potential application in the operating room. The authors also performed a detailed review of the potential limitations and possible improvements. Conclusions: This new software has the potential to be incorporated into the existing workflow environment of the ultrasound systems in the future, making it clinically feasible to perform perioperative RV volume analysis. [ABSTRACT FROM AUTHOR]

Background: Malunion after displaced fractures of the clavicle can result in varying degrees of scapular malalignment and potentially scapular winging. The purpose of our study was to quantify the scapular malalignment in patients with midshaft clavicle malunions showing scapular winging. Methods: Eighteen patients with symptomatic midshaft clavicle malunions showing scapular winging were identified and underwent standardized computed tomography scanning of the thorax. Specific bony landmarks on the clavicle and scapula were digitized, allowing generation of 3-dimensional points. These points were acquired bilaterally so that relative translations comparing the malunited side with the contralateral side could be obtained. Statistical analysis using a paired t test was performed. Results: The mean time from fracture to examination was 42.9 months. There were 15 men and 3 women with a mean age of 41.6 years. The mean clavicular shortening was 21.1 mm (P = .0000004). The acromion of the affected scapula on average translated 24.3 mm. The components of this translation were medial, 11.9 mm (P = .00008); inferior, 20.7 mm (P = .0009); and anterior, 4.6 mm (P = .02). Posterior bony landmarks on the scapula including the superior and inferior angles of the scapula translated a total of 9.9 mm and 5.9 mm, respectively. Conclusion: This is the first study to document the degree of scapular malalignment in patients with symptomatic clavicle malunions showing scapular winging. The acromion closely follows the distal clavicular fragment and translates medially, inferiorly, and anteriorly. The translations of the superior and inferior angles of the scapula are quite variable in magnitude and direction, and on average, these angles translate substantially less than the acromion. [ABSTRACT FROM AUTHOR]

3D woven structures provide attractive features for use as composite reinforcements and this evolution has been driven in response to need in the emerging industrial applications i.e. for making preforms for construction, automotive ballistics, marine and other applications. The composites produced from 3D woven fabrics have higher delamination resistance, ballistic damage resistance, impact damage tolerance and dimensional stability as well. These fore mentioned properties have been a major problem in composites produced with traditional 2D weaving specially used in military aircraft structures. This paper includes the manufacturing techniques of multilayer, orthogonal and angle interlock - 3 Dimensional solid woven fabrics. Instead of being laid layer upon layer to form the thickness, 3D woven structure can produce the thickness dimension during the weaving process. The amount and types of binder yarns such as carbon, glass, kevlar and ceramic fibres in through-thickness can be used to tailor the properties of composites for specific industrial applications. Also, layer sequence can be arranged based on the requirements. Such kind of fabrics can be fabricated on conventional weaving loom by minor modifications. This will be the future technological challenge in this area. [ABSTRACT FROM AUTHOR]

Background: Little 3-dimensional biomechanical investigation of plastic bowing deformity of the ulna has been reported, and the purpose of this study was to conduct such an investigation to elucidate mechanisms of injury and appropriate treatments. Methods: Ten cases of traumatic plastic deformity of the ulna in pediatric patients, 4 with chronic radial head dislocations (Monteggia equivalent) and 6 with malunited radial shaft fractures, were analyzed for rotational deformities in the axial plane and bending deformities in the sagittal and coronal planes in Euler angle space by use of a 3-dimensional computerized simulation system with a markerless registration technique. Results: Deformed ulnae with radial head dislocations had 18.7° ± 17.4° of external rotation in the axial plane and 10.4° ± 7.0° of extension in the sagittal plane whereas those with malunited radial shaft fractures had 12.5° ± 12.7° of internal rotation and 6.3° ± 5.6° of flexion displacement compared with mirror images of the opposite ulnae. Absolute values of rotational deformities in both groups were larger than those of sagittal and coronal bending deformities. Discussion: Most major traumatic plastic bowing deformities of the ulna involved rotation rather than bending. External rotational stress on the ulna is suspected to cause radial head dislocation, and internal rotational stress results in radial shaft fracture during falls onto outstretched arms. Therefore the correction of rotational deformities of the ulna should be considered in the treatment of chronic radial head dislocations and malunited radial shaft fractures. [ABSTRACT FROM AUTHOR]

Objective: The proximal isovelocity surface area (PISA) is used for the echocardiographic quantification of effective orifice areas in valvular stenosis and regurgitation. Typically measured in 2 dimensions, the PISA relies on the geometric assumption that the shape of flow convergence is a hemisphere and that the orifice is a single circular point. Neither assumption is true. The objective was to develop a method for automating the measurement of the PISA in 3 dimensions and to illuminate the actual shape of the flow convergence pattern and how it changes over time. Design: Retrospective, single-case study. Setting: Major urban hospital. Participants: This study was based on a single patient undergoing mitral valve replacement. Interventions: No additional interventions were performed in the patient. Results: The effective orifice areas calculated from the serial hemispheric, hemi-elliptic, and 3-dimensional (3D) PISAs during diastole were compared with the corresponding planimetric anatomic mitral orifice area. The effective orifice areas based on the manual and automated measurements of 3D PISAs more closely approximated the anatomic orifice than the effective orifice areas calculated using hemispheric or hemi-elliptic PISAs. Conclusions: An automated analysis of 3D color Doppler data is feasible and allows a direct and accurate measurement of a 3D PISA, thus avoiding reliance on simplistic geometric assumptions. The dynamic aspect of cardiac orifices also must be considered in orifice analysis. [ABSTRACT FROM AUTHOR]

Summary: Objectives/Hypothesis: Laryngeal electromyography (LEMG) is an important tool for the assessment of laryngeal nerve and muscle functioning. The purpose of the study was to determine electrode insertion angle and insertion depth for the various laryngeal muscles. Methods: Twenty-three cadaver larynges were examined with magnetic resonance tomography (MRT) and Materialize Interactive Medical Image Control System (Leuven, Belgium) 3-dimensional (3D) imaging software. Geometrical analysis was used to calculate the electrode insertion angles. Results: All laryngeal muscles could be identified and 3D visualized on MRT scans. Although the insertion angles were the same in male and female larynges, the insertion depth was significantly larger in male than in female larynges (P <0.05). Of particular clinical importance is the fact that the electrode has to be directed lateral and upward for the thyroarytenoid muscle but lateral and downward for the lateral cricoarytenoid muscle (insertion point=midline lower border of the thyroid). Conclusions: This is the first study that analyzes electrode insertion angles and insertion depths for each laryngeal muscle using 3D imaging. We hope that the information gained from this study will help clinicians performing LEMG to localize the individual laryngeal muscles. [Copyright &y& Elsevier]

Coronary artery bifurcations are a common challenging lesion subset accounting for approximately 10% to 20% of all percutaneous coronary interventions. The provisional T-stenting approach is generally recommended as the first-line management of most lesions. Carina shift is suggested to be the predominant mechanism of side-branch pinching during provisional T-stenting and has been indirectly inferred from bench work and other intravascular imaging modalities. Offline 3-dimensional (3D) reconstructions of patients studied in the first-in-man trial of the high-frequency (160 frames/s) Terumo optical frequency domain imaging system were undertaken using volume-rendering software. Through a series of 3D reconstructions, several novel hypothesis-generating concepts are presented. [Copyright &y& Elsevier]

Hypothesis: Scapular cortical thickness has not been fully characterized from the perspective of determining optimal screw placement for securing the glenoid base plate in reverse shoulder arthroplasty. Materials and methods: Twelve fresh frozen cadaveric scapulae underwent high resolution CT scans with 3-dimensional reconstructions and wall thickness analysis. Digital base plates were positioned and virtual screws were placed according to 2 scenarios: A - intraosseous through the entire course and exits a “safe region” with no known neurovascular structures; B - may leave and re-enter the bone and penetrates the thickest cortical region accessible regardless of adjacent structures. Results: For scenario A, the optimal screw configurations were: (superior screw) length = 35 mm, 9° superior, 2° posterior; (inferior screw-A) length = 34 mm, 16° inferior, 5° anterior; (inferior screw-B) length = 31 mm, 31 inferior, 4 posterior; (posterior screw) length 19 mm, 29° inferior, 3° anterior. For scenario B: (superior screw) length = 36 mm, 28° superior, 10° anterior; (inferior screw) length = 35 mm, 19° inferior, 4° anterior; (posterior screw) length 37 mm, 23° superior, 3° anterior. The anterior screw was consistent between scenarios A and B, averaged 29 mm in length and was directed 16° inferior and 14° posterior. Conclusion: Thicker cortical regions were present in the lateral aspect of the suprascapular notch, scapular spine base, anterior/superior aspect of inferior pillar and junction of glenoid neck and scapular spine. Regions with high cortical thickness were accessible for both scenarios except for the posterior screw in scenario A. [ABSTRACT FROM AUTHOR]

Objectives: We explore the bifurcation angle (BA) parameters of the left main coronary artery (LM), the effect of percutaneous coronary intervention (PCI) on this angulation, and the impact of BA on clinical outcome. Background: The BA is emerging as a predictor of outcome after PCI of bifurcation lesions. Three-dimensional (3D) quantitative coronary angiography (QCA) overcomes the shortcomings of 2-dimensional analysis and provides reliable data. Methods: This is a substudy of the SYNTAX (SYNergy Between Percutaneous Coronary Intervention With TAXus and Cardiac Surgery) trial. The cineangiograms of the 354 patients who underwent PCI of their LM stem were analyzed with 3D QCA software (CardiOp-B, Paieon Medical, Ltd., Rosh Ha''ayin, Israel). The proximal BA (between LM and left circumflex [LCX]) and the distal BA (between left anterior descending and LCX) were computed in end-diastole and end-systole, both before and after PCI. The cumulative major adverse cardiac and cardiovascular event (MACCE) rates throughout the 12-month period after randomization were stratified across pre-PCI distal BA values and compared accordingly. Results: Complete analysis was feasible in 266 (75.1%) patients. Proximal and distal BA had mean pre-PCI end-diastolic values of 105.9 ± 21.7° and 95.6 ± 23.6°, respectively, and were inversely correlated (r = −0.75, p < 0.001). During systolic motion of the heart there was an enlargement of the proximal angle and a reduction of the distal angle (ΔBA −8.2° and 8.5°, respectively, p < 0.001 for both). The PCI resulted in a mean decrease in the distal BA (ΔBA 4.5°, p < 0.001). The MACCE rates did not differ across distal BA values; freedom from MACCE at 12 months was 82.8%, 85.4%, and 81.1% (p = 0.74) for diastolic values (first through third tertile). Conclusions: Left main BA analysis with 3D QCA is feasible. Both proximal and distal angles are affected by cardiac motion; PCI modifies the distal angle. There is no clear difference in event rates across pre-PCI distal BA values. [Copyright &y& Elsevier]

Abstract: Two hundred twenty-three patients with osteoarthritic hips were analyzed using computed tomography and a specific image processing software (HIP-PLAN®) to determine 3-dimensional morphological data of the hip focusing on femoral offset (FO). Mean FO was found to be 42.2 ± 5.1 mm, 2.2 mm greater than the 2-dimensional FO values reported in the literature. The FO was found to be above 45 mm in 31% of patients and greater than 50 mm in 12%. The error associated with the use of conventional plane x-rays to measure FO was found to be 3.5 ± 2.5 mm, the x-ray technique generally underestimating the measure of FO. The sum of acetabular and femoral anteversion was found to be out of the safe zone regarding dislocation risk in 47% of patients. [Copyright &y& Elsevier]

Objective: To assess the plotting reproducibility of landmarks on 3-dimensional computed tomography (3D-CT) images through use of the 95% confidence ellipse in order to propose sufficiently stable coordinate systems for 3D-CT measurements. Materials and Methods: Six dentists plotted 19 landmarks twice on 3D-CT images. Scatterplots and the 95% ellipses were produced 3-dimensionally, and the areas of the ellipses were calculated for evaluating the reproducibility of landmarks. Results: The plotting reproducibility of each landmark showed characteristic features. Among five landmarks (the sella [S], nasion [N], basion [Ba], orbitale [Or], and true porion [Po]) that are frequently used as reference points on cephalograms, Ba showed the smallest areas for all three coordinate axes, indicating high reproducibility. The coronoid process (CP) and the tooth-related landmarks showed relatively high reproducibility. Conclusion: Sufficiently stable coordinate axes could be proposed for different treatments and studies. [ABSTRACT FROM AUTHOR]

To compare the accuracy of evaluating deformity in distal radius malunions using plain radiographic measurements compared with a 3-dimensional method involving 3-dimensional computer bone models. Consecutive patients who had an extra-articular distal radius malunion were included. Standard radiographs and computed tomography scans of both wrists were performed. Palmar tilt, radial tilt, and ulnar variance were measured on radiographs. The computed tomography scan data were sent to a workstation and 3-dimensional bone surface models of the radius were created. The 3-dimensional palmar tilt, 3-dimensional radial tilt, 3-dimensional ulnar variance, and axial rotational deformity were calculated. Thirteen patients, mean age 40 years (range, 22–57 years) were included. The 3 3-dimensional values were positively correlated with their corresponding radiographic values. Nevertheless, the 3-dimesional palmar tilt and 3-dimensional radial tilt values were slightly smaller than the radiographic palmar tilt and radial tilt. The quantitative difference between the 3-dimensional method and plain radiographs was on average 2° for the dorsal deformity group and 3° for the palmar deformity group. The 3-dimensional ulnar variance was significantly higher than the radiographic ulnar variance by an average of +1.3 mm for malunions with dorsal tilt and +0.6 mm for malunions with palmar tilt. The 3-dimensional method allowed us to measure the extent of the axial rotational deformity, which was 9° on average (range, 2° to 21°). Despite small differences, measurements made on both plain radiographs and 3-dimensional computer bone models are accurate for evaluating the deformity in extra-articular distal radius malunions. Our 3-dimensional method seems to provide a more accurate measurement of ulnar variance, particularly for dorsally angulated cases, and is helpful for measuring rotational malalignment. In this study, we found that either a 3-dimensional computer bone model or plain radiographs can be used as a benchmark to evaluate the deformity of extra-articular distal radius malunion. The 3-dimensional method can also be used to define axial rotational deformity. [ABSTRACT FROM AUTHOR]

Purpose This study primarily aimed to demonstrate the screw-home rotation of the thumb carpometacarpal (CMC) joint and the function of surrounding ligaments during thumb oppositional motion. Methods A 3-dimensional kinematic analysis of the thumb CMC joint was conducted using data derived from computed tomography of 9 healthy volunteers. Scans were obtained in the neutral forearm and wrist position and the thumb in maximum radial abduction, maximum palmar abduction, and maximum opposition. The movements of the first metacarpal and the palmar and dorsal bases on the trapezium during thumb oppositional motion from radial abduction through palmar abduction were quantified using a coordinate system originating on the trapezium. In addition to the kinematic analyses, the length of virtual ligaments, including the anterior oblique, ulnar collateral, dorsal radial, dorsal central (DCL), and posterior oblique ligament (POL), were calculated at each thumb position. Results From radial abduction to opposition of the thumb through palmar abduction, the first metacarpal was abducted, internally rotated, and flexed on the trapezium. The palmar base of the first metacarpal moved in the palmar-ulnar direction, and the dorsal base moved in the palmar-distal direction along the concave surface of the trapezium. Although the DCL and POL lengthened, the lengths of other ligaments did not change significantly. Conclusions During thumb oppositional motion, internal rotation of the first metacarpal occurred, with the palmar base rotating primarily with respect to the dorsal base. The DCL and POL may be strained in thumb functional positions. Clinical relevance Kinematic variables indicated a screw-home rotation of the thumb CMC joint and the contribution of the dorsal ligaments to the stability of the rotation on the pivot point. [ABSTRACT FROM AUTHOR]

Background: Traditionally, 2-dimensional ultrasound parameters have been used for the diagnosis of a suspected morbidly adherent placenta previa. More objective techniques have not been well studied yet.Objective: The objective of the study was to determine the ability of prenatal 3-dimensional power Doppler analysis of flow and vascular indices to predict the morbidly adherent placenta objectively.Study Design: A prospective cohort study was performed in women between 28 and 32 gestational weeks with known placenta previa. Patients underwent a two-dimensional gray-scale ultrasound that determined management decisions. 3-Dimensional power Doppler volumes were obtained during the same examination and vascular, flow, and vascular flow indices were calculated after manual tracing of the viewed placenta in the sweep; data were blinded to obstetricians. Morbidly adherent placenta was confirmed by histology. Severe morbidly adherent placenta was defined as increta/percreta on histology, blood loss >2000 mL, and >2 units of PRBC transfused. Sensitivities, specificities, predictive values, and likelihood ratios were calculated. Student t and χ2 tests, logistic regression, receiver-operating characteristic curves, and intra- and interrater agreements using Kappa statistics were performed.Results: The following results were found: (1) 50 women were studied: 23 had morbidly adherent placenta, of which 12 (52.2%) were severe morbidly adherent placenta; (2) 2-dimensional parameters diagnosed morbidly adherent placenta with a sensitivity of 82.6% (95% confidence interval, 60.4-94.2), a specificity of 88.9% (95% confidence interval, 69.7-97.1), a positive predictive value of 86.3% (95% confidence interval, 64.0-96.4), a negative predictive value of 85.7% (95% confidence interval, 66.4-95.3), a positive likelihood ratio of 7.4 (95% confidence interval, 2.5-21.9), and a negative likelihood ratio of 0.2 (95% confidence interval, 0.08-0.48); (3) mean values of the vascular index (32.8 ± 7.4) and the vascular flow index (14.2 ± 3.8) were higher in morbidly adherent placenta (P < .001); (4) area under the receiver-operating characteristic curve for the vascular and vascular flow indices were 0.99 and 0.97, respectively; (5) the vascular index ≥21 predicted morbidly adherent placenta with a sensitivity and a specificity of 95% (95% confidence interval, 88.2-96.9) and 91%, respectively (95% confidence interval, 87.5-92.4), 92% positive predictive value (95% confidence interval, 85.5-94.3), 90% negative predictive value (95% confidence interval, 79.9-95.3), positive likelihood ratio of 10.55 (95% confidence interval, 7.06-12.75), and negative likelihood ratio of 0.05 (95% confidence interval, 0.03-0.13); and (6) for the severe morbidly adherent placenta, 2-dimensional ultrasound had a sensitivity of 33.3% (95% confidence interval, 11.3-64.6), a specificity of 81.8% (95% confidence interval, 47.8-96.8), a positive predictive value of 66.7% (95% confidence interval, 24.1-94.1), a negative predictive value of 52.9% (95% confidence interval, 28.5-76.1), a positive likelihood ratio of 1.83 (95% confidence interval, 0.41-8.11), and a negative likelihood ratio of 0.81 (95% confidence interval, 0.52-1.26). A vascular index ≥31 predicted the diagnosis of a severe morbidly adherent placenta with a 100% sensitivity (95% confidence interval, 72-100), a 90% specificity (95% confidence interval, 81.7-93.8), an 88% positive predictive value (95% confidence interval, 55.0-91.3), a 100% negative predictive value (95% confidence interval, 90.9-100), a positive likelihood ratio of 10.0 (95% confidence interval, 3.93-16.13), and a negative likelihood ratio of 0 (95% confidence interval, 0-0.34). Intrarater and interrater agreements were 94% (P < .001) and 93% (P < .001), respectively.Conclusion: The vascular index accurately predicts the morbidly adherent placenta in patients with placenta previa. In addition, 3-dimensional power Doppler vascular and vascular flow indices were more predictive of severe cases of morbidly adherent placenta compared with 2-dimensional ultrasound. This objective technique may limit the variations in diagnosing morbidly adherent placenta because of the subjectivity of 2-dimensional ultrasound interpretations. [ABSTRACT FROM AUTHOR]