108 results on '"Selkoe, Dennis J"'
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2. Multiple Levels of Synaptic Regulation by NMDA-type Glutamate Receptor in Normal and Disease States
3. The seventh age of man: Solving senility
4. The Impact of Novel Treatments on Aβ Burden in Alzheimer’s Disease: Insights from A Mathematical Model
5. Ubiquitination of a Novel form of α-Synuclein by Parkin
6. Colocalization of Parkin with α-Synuclein in the Lewy Bodies of Parkinson Disease
7. Cell Biology of Amyloidogenesis: An overview
8. Role of presenilin in APP processing and Aβ production
9. The Pathophysiology of Alzheimer’s Disease
10. Amyloid ß-Protein Deposition as a Seminal Pathogenetic Event in Alzheimer’s Disease
11. Normal Production of the Amyloid β-Protein and the Pathogenesis of Alzheimer’s Disease
12. In Vitro Production of Amyloid β-Protein: A Route to the Mechanism and Treatment of Alzheimer’s Disease
13. The Fibrous Proteins of Brain: A Primer for Gerontologists
14. Molecular Properties of Paired Helical Filaments and Senile Plaque Amyloid Fibers in Alzheimer’s Disease
15. Intraneuronal and Extracellular Filaments in the Pathogenesis of Alzheimer’s Disease
16. Biochemical and Structural Studies of Paired Helical Filaments and Senile Plaque Amyloid in Alzheimer’s Disease
17. α-1-Antichymotrypsin, a Serine Protease Inhibitor, is a Component of the Amyloid Deposits in Alzheimer’s Disease
18. Why Alzheimer’s is a Disease of Memory: Synaptic Targeting by Pathogenic Aβ Oligomers (ADDLs)
19. Impact of Beta Amyloid on Excitatory Synaptic Transmission and Plasticity
20. Quantitative Neuropathology in Alzheimer’s Mouse Models
21. Synapse Loss, Synaptic Plasticity and the Postsynaptic Density
22. Imaging of Experience-Dependent Structural Plasticity in the Mouse Neocortex in vivo
23. Long-Term Potentiation and Aβ: Targeting Aβ Species, Cellular Mechanisms and Putative Receptors
24. Cellular Biology of AMPA Receptor Trafficking and Synaptic Plasticity
25. Aβ-Induced Toxicity Mediated by Caspase Cleavage of the Amyloid Precursor Protein (APP)
26. Permanence of the Synapse and Molecular Instability
27. Synaptic Transmission Dynamically Modulates Interstitial Fluid Amyloid-β Levels
28. Genes, Synapses and Autism Spectrum Disorders
29. Molecular and cellular pathways towards and away from Alzheimer’s disease
30. Paquid: an integrated, multidisciplinary, population-based approach to normal and pathological cerebral aging
31. The Search for structure of tau and paired helical filaments
32. Ubiquitin is a component of paired helical filaments in Alzheimer’s disease
33. Influence of tau on neuronal traffic mechanisms
34. The Alzheimer tangle — 100 years on.
35. Bulk isolation of neurofibrillary tangles and discoveries of tau and its abnormal hyperphosphorylation
36. Vision for the future : Alzheimer’s Disease: Pathogenesis, Models and Experimental Therapeutics
37. Apolipoprotein E4: From synaptic remodeling to genetic risk factor in both familial and sporadic Alzheimer’s disease
38. Tau focused drug discovery for Alzheimer’s disease and related Neurodegenerative Tauopathies
39. Immunological demonstration of tau protein in neurofibrillary tangles
40. The natural and molecular history of Alzheimer’s disease: Tau is part of the story
41. The Presenilin/gamma-secretase complex and its potential as a drug target in Alzheimer’s Disease
42. Apolipoprotein E and Alzheimer’s disease: A brief retrospective
43. Identification of β-secretase
44. Targeting γ-Secretase for Alzheimer’s Disease
45. Activation of α-secretase as an approach for treatment of Alzheimer’s disease
46. Synaptic activity, amyloid-β and Alzheimer’s disease
47. Physiological generation of Amyloid β-peptide and its Consequences for Alzheimer’s disease research
48. Genetics, molecular biology, and animal modeling of Alzheimer’s disease
49. Mutation of the Alzheimer’s disease amyloid gene in hereditary cerebral hemorrhage, Dutch type. The role of amyloid in dementia and stroke
50. The genetic Alzheimer-frontotemporal dementia spectrum
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