202 results on '"Yamazaki, Hiroshi"'
Search Results
2. A variety of cytochrome P450 enzymes and flavin-containing monooxygenases in dogs and pigs commonly used as preclinical animal models
3. Identification of cytochrome P450 2C18 and 2C76 in tree shrews: P450 2C18 effectively oxidizes typical human P450 2C9/2C19 chiral substrates warfarin and omeprazole with less stereoselectivity
4. Convection and joint characteristics in aluminum alloy melting zone during resistance spot welding of dissimilar Fe-Al material in external magnetic field
5. Molecular and functional characterization of flavin-containing monooxygenases (FMO1–6) in tree shrews
6. Kinetics of the inhibition of CYP3A4 and CYP2C19 activity by jabara juice and identification of the responsible inhibitory components
7. Simple confirmation methods for rare but impaired variants of human flavin-containing monooxygenase 3 (FMO3) found in an updated genome resource databank
8. SGX523 causes renal toxicity through aldehyde oxidase-mediated less-soluble metabolite formation in chimeric mice with humanized livers
9. Effects of the FCC catalyst binder type on propylene production during catalytic cracking of VGO
10. A study on convection in molten zone of aluminum alloy during Fe/Al resistance spot welding
11. Newly identified cytochrome P450 3A genes of tree shrews and pigs are expressed and encode functional enzymes
12. High hepatic and plasma exposures of atorvastatin in subjects harboring impaired cytochrome P450 3A4∗16 modeled after virtual administrations and possibly associated with statin intolerance found in the Japanese adverse drug event report database
13. Novel cytochrome P450 1 (CYP1) genes in tree shrews are expressed and encode functional drug-metabolizing enzymes
14. Imaging Mass Spectrometry (IMS) for drug discovery and development survey: Results on methods, applications and regulatory compliance
15. Impact of nitrogen compound variability of sewage treated water on N2O production in riverbeds
16. Radiographic Change in Articular Reduction After Volar Locking Plating for Intra-Articular Distal Radius Fractures
17. Interhemispheric auditory connectivity requires normal access to sound in both ears during development
18. Determination and prediction of permeability across intestinal epithelial cell monolayer of a diverse range of industrial chemicals/drugs for estimation of oral absorption as a putative marker of hepatotoxicity
19. Changes in the Functional Range of Motion of the Thumb Metacarpophalangeal Joint After Trapeziometacarpal Arthrodesis for Patients With Advanced Trapeziometacarpal Osteoarthritis
20. Relationship between wire orientation and optical and electrical anisotropy in silver nanowire/polymer composite films
21. Investigation of the acidic nature of MCM-68 zeolite based on the adsorption of CO and bulky probe molecules
22. Ultra-high-speed optical transmission using digital-preprocessed analog-multiplexed DAC
23. Minimally invasive percutaneous transluminal renal artery stenting
24. Roles of human cytochrome P450 1A2, 2C9, and 3A4/5 enzymes in drug oxidations mediated by metabolically inactivated human hepatocytes in previously transplanted chimeric mice
25. Transcript abundance of hepatic drug-metabolizing enzymes in two dog breeds compared with 14 species including humans
26. Rare but impaired flavin-containing monooxygenase 3 (FMO3) variants reported in a recently updated Japanese mega-databank of genome resources
27. Saliva pH affects the sweetness sense
28. Characterization of microminipigs as an in vivo experimental model for cardiac safety pharmacology
29. Sex- and age-dependent gene expression in human liver: An implication for drug-metabolizing enzymes
30. Upholding science in health, safety and environmental risk assessments and regulations
31. Tactile sensing for object identification based on hetero-core fiber optics
32. Audio–visual integration during speech perception in prelingually deafened Japanese children revealed by the McGurk effect
33. Risk Assessment of Tendon Attrition Following Treatment of Distal Radius Fractures With Volar Locking Plates Using Audible Crepitus and Placement of the Plate: A Prospective Clinical Cohort Study
34. Early Postoperative Screening by Contrast-Enhanced CT and Prophylactic Embolization of Detected Pseudoaneurysms Prevents Delayed Hemorrhage after Partial Nephrectomy
35. Human urine and plasma concentrations of bisphenol A extrapolated from pharmacokinetics established in in vivo experiments with chimeric mice with humanized liver and semi-physiological pharmacokinetic modeling
36. Hexamethyleneimine and pivalonitrile as location probe molecules of Lewis acid sites on MWW-type zeolites
37. Genetic polymorphism of cynomolgus and rhesus macaque CYP2C9
38. Benzydamine N-oxygenation as an index for flavin-containing monooxygenase activity and benzydamine N-demethylation by cytochrome P450 enzymes in liver microsomes from rats, dogs, monkeys, and humans
39. Roles of human cytochrome P450 3A4/5 in dexamethasone 6β-hydroxylation mediated by liver microsomes and humanized liver in chimeric mice metabolically suppressed with azamulin
40. A family study of compound variants of flavin-containing monooxygenase 3 (FMO3) in Japanese subjects found by urinary phenotyping for trimethylaminuria
41. Pharmacokinetics and effects on serum cholinesterase activities of organophosphorus pesticides acephate and chlorpyrifos in chimeric mice transplanted with human hepatocytes
42. Human plasma concentrations of herbicidal carbamate molinate extrapolated from the pharmacokinetics established in in vivo experiments with chimeric mice with humanized liver and physiologically based pharmacokinetic modeling
43. Effect of Ketoconazole on the Pharmacokinetics of the Dipeptidyl Peptidase-4 Inhibitor Teneligliptin: An Open-Label Study in Healthy White Subjects in Germany
44. Stem cell self-renewal factors Bmi1 and HMGA2 in head and neck squamous cell carcinoma: clues for diagnosis
45. Further survey of genetic variants of flavin-containing monooxygenase 3 (FMO3) in Japanese subjects found in an updated database of genome resources and identified by phenotyping for trimethylaminuria
46. Plasma concentrations of melengestrol acetate in humans extrapolated from the pharmacokinetics established in in vivo experiments with rats and chimeric mice with humanized liver and physiologically based pharmacokinetic modeling
47. Mechanism-based Inhibition of CYP1A1 and CYP3A4 by the Furanocoumarin Chalepensin
48. Clinical Evidence of Pharmacokinetic Changes in Thalidomide Therapy
49. Essex-Lopresti injury treated with radial head replacement and interosseous membrane reconstruction using synthetic graft: A case report
50. Cytochrome P450-dependent drug oxidation activities and their expression levels in liver microsomes of chimeric TK-NOG mice with humanized livers
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