55 results on '"Van Leuven, Fred"'
Search Results
2. Dendritic Degeneration, Neurovascular Defects, and Inflammation Precede Neuronal Loss in a Mouse Model for Tau-Mediated Neurodegeneration
3. Potential amyloid plaque-specific peptides for the diagnosis of Alzheimer's disease
4. Occurrence and co-localization of amyloid β-protein and apolipoprotein E in perivascular drainage channels of wild-type and APP-transgenic mice
5. Mice lacking Dfna5 show a diverging number of cochlear fourth row outer hair cells
6. Reduction of β-amyloid plaques in brain of transgenic mouse model of Alzheimer’s disease by EFRH-phage immunization
7. Secretases as targets for the treatment of Alzheimer's disease: the prospects
8. The use of Achilles tendon ultrasonography for the diagnosis of familial hypercholesterolemia
9. Acetylcholinesterase-Positive Fiber Deafferentation and Cell Shrinkage in the Septohippocampal Pathway of Aged Amyloid Precursor Protein London Mutant Transgenic Mice
10. Behavioral Disturbances without Amyloid Deposits in Mice Overexpressing Human Amyloid Precursor Protein with Flemish (A692G) or Dutch (E693Q) Mutation
11. Prominent Axonopathy in the Brain and Spinal Cord of Transgenic Mice Overexpressing Four-Repeat Human tau Protein
12. A liposomal anti-phospho-tau vaccine demonstrates higher immunogenicity and specificity than a classical peptide vaccine approach
13. O-GlcNAc-ase inhibitor improves the clinical conditions of Alzheimer's disease mice
14. Treating Alzheimer's disease with an O-GlcNAcase inhibitor
15. Phospho-tau–specific vaccine for the treatment of tau pathology
16. Timeline of biochemical and pathological markers in mono- and Bigenic models for tauopathy
17. Identification of the tau interactome in mouse brain
18. Cognitive abilities of Alzheimer transgenic mice as revealed by the IntelliCage system
19. Identification of proteins that form complexes with tau in mouse brain
20. The amyloid-GSK3-tau connection to neurodegeneration revealed by combining transgenic and viral models
21. Phenotypic and genetic subclassification of Alzheimer's disease
22. Genetic screening for components mediating α-synuclein toxicity in a humanized yeast model system
23. The safety profile of ACI-24, an oligo-specific amyloid beta vaccine, demonstrated decrease of large microbleedings in brain of aged Alzheimer's disease mouse model
24. In vivo analysis of the effect of mutant PS1 on dendritic spines in the somatosensory cortex of transgenic mice
25. P4-190: Role of gamma-secretase in lipoprotein endocytosis
26. P1-128: Humanized yeast cells recapitulate basic mechanisms of the protein Tau phosphorylation-conformation-aggregation cascade
27. P1-039: Dendritic defects in transgenic mice that model various aspects of Alzheimer's disease
28. P1-005: AAV-based paradigm for amyloid and Tau pathology as in vivo model for Alzheimer's disease
29. O4-01-08: Neurodegeneration and neuroinflammation in cdk5/p25 inducible mice: A model for hippocampal sclerosis and neocortical degeneration
30. O4-01-01: Analysis of the metabolism of amyloid precursor protein and of protein tau in mice with neuron-specific postnatal deficiency of Gsk3β
31. O3-05-03: Therapeutic effects of passive immunization with an Aβ-oligomer– specific antibody in APP transgenic mice
32. O2-02-05: Amyloid causes tauopathy by activating GSK3
33. P3-277: Severe neurodegeneration is intimately related to inflammation in cdk5/p25 inducible mice
34. P3-283: Differential regulation of microglial cytokine production, phagocytosis and migration by norepinephrine: How locus ceruleus degeneration affects Alzheimer disease
35. P2-037: Modelling of differential phosphorylation, conformation and aggregation of protein tau in yeast is extended to its binding to microtubuli in vitro
36. P2-034: Deletion of genes responsible for vesicular transport in yeast causes mislocalization and enhanced toxicity of α-synuclein
37. P2-033: Molecular determinants of the phosphorylation and aggregation of human protein tau in a yeast model
38. P1-015: Tau-4R suppresses precursor proliferation and promotes neuronal differentiation in the hippocampus of humanized tau knock-in/knock-out mice
39. PL-05-02: Animal models: Amyloid and tau do not mix well
40. O4-05-04: Co-expression of GSK-3β with tau-P301L in double transgenic mice dramatically increases forebrain tauopathy but decreases hindbrain pathology and rescues mortality
41. O3-03-08: Differential effects of presenilin-1 deficiency and mutant presenilin-1 on synaptic plasticity
42. O2-04-01: Combined amyloid and tau-pathology in APPV717I X taup301L double transgenic mice: Increased survival correlates with less hindbrain pathology, despite dramatic forebrain tauopathy
43. P4-203 Peroxisome proliferator-activated receptor-γ (PPAR-γ) agonists modulate immunostimulated processing of APP through regulation of β-secretase (BACE)
44. Altered IP3-dependent intracellular Ca 2+ pools of hippocampal neurons in presenilin-1 mutant transgenic mice
45. Prominent cerebral amyloid angiopathy in transgenic mice overexpressing the London mutant of human APP in neurons
46. Neuronal expression of human apolipoprotein E4 increases protein tau phosphorylation in transgenic mice
47. Rescue of protein tau-induced axonopathy by GSK-3β in [GSK-3β X HTAU-4R] double transgenic mice
48. Impact of PS mutations and PS null state in adult transgenic mouse brain
49. Specificity of a wheat gluten aspartic proteinase
50. Amyloid precursor protein is not processed by furin, PACE 4, PC1/3, PC2, PC4 and PC5/6 of the furin family of proprotein processing enzymes
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