21 results on '"Neckers, Len"'
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2. Optical and Radioiodinated Tethered Hsp90 Inhibitors Reveal Selective Internalization of Ectopic Hsp90 in Malignant Breast Tumor Cells
3. Englerin A Stimulates PKCθ to Inhibit Insulin Signaling and to Simultaneously Activate HSF1: Pharmacologically Induced Synthetic Lethality
4. UOK 262 cell line, fumarate hydratase deficient ( FH−/ FH−) hereditary leiomyomatosis renal cell carcinoma: in vitro and in vivo model of an aberrant energy metabolic pathway in human cancer
5. KIT regulates tyrosine phosphorylation and nuclear localization of β-catenin in mast cell leukemia
6. HIF overexpression correlates with biallelic loss of fumarate hydratase in renal cancer: Novel role of fumarate in regulation of HIF stability
7. A novel form of mastocytosis associated with a transmembrane c-kit mutation and response to imatinib
8. 17-Allylamino-17-demethoxygeldanamycin (17-AAG) is effective in down-regulating mutated, constitutively activated KIT protein in human mast cells
9. Heat shock protein 90 as a molecular target for cancer therapeutics
10. Microtubule Disruption Utilizes an NFκB-dependent Pathway to Stabilize HIF-1α Protein
11. Hsp90 inhibitors as novel cancer chemotherapeutic agents
12. Ras, ROS and Proteotoxic Stress: A Delicate Balance
13. Hsp90 as an anti-cancer target
14. Methoxychalcone inhibitors of androgen receptor translocation and function
15. A non-toxic Hsp90 inhibitor protects neurons from Aβ-induced toxicity
16. MP35-12 THE HSP90 INHIBITOR GANETESPIB SYNERGIZES WITH THE MET KINASE INHIBITOR CRIZOTINIB IN BOTH CRIZOTINIB-SENSITIVE AND CRIZOTINIB-RESISTANT MET-DRIVEN RENAL TUMOR MODELS
17. Activity of the tyrosine kinase inhibitor PKC412 in a patient with mast cell leukemia with the D816V KIT mutation
18. 1242: A Phase 2 Study of 17-Allylamino-17-Demethoxygeldanamycin (17AAG) in Patients with Von Hippel Lindau (VHL) Disease and Renal Tumors
19. Novel Mechanism of Activated FLT3-Associated Leukemogenisis: FLT3 Regulates Wnt Signaling by Phosphorylating β-Catenin and Promoting β-Catenin Nuclear Localization.
20. Chapter 58 - Heat Shock Protein 90 and the Proteasome: Housekeeping Proteins Become Novel Molecular Targets for Cancer Therapy
21. List of Contributing Authors
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