23 results on '"Kozielski, Frank"'
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2. Comparison of the pH- and thermally-induced fluctuations of a therapeutic antibody Fab fragment by molecular dynamics simulation
3. Crystal structure of the Eg5 - K858 complex and implications for structure-based design of thiadiazole-containing inhibitors
4. New MKLP-2 inhibitors in the paprotrain series: Design, synthesis and biological evaluations
5. STLC-resistant cell lines as tools to classify chemically divergent Eg5 targeting agents according to their mode of action and target specificity
6. “Snapshots” of Ispinesib-induced Conformational Changes in the Mitotic Kinesin Eg5
7. Doing the methylene shuffle – Further insights into the inhibition of mitotic kinesin Eg5 with S-trityl l-cysteine
8. Inhibition of hepatitis C virus NS5B polymerase by S-trityl-l-cysteine derivatives
9. Elucidating the functionality of kinesins: An overview of small molecule inhibitors
10. Mutations in the human kinesin Eg5 that confer resistance to monastrol and S-trityl- l-cysteine in tumor derived cell lines
11. Structure of Human Eg5 in Complex with a New Monastrol-based Inhibitor Bound in the R Configuration
12. New chemical tools for investigating human mitotic kinesin Eg5
13. S-Trityl-L-cysteine Is a Reversible, Tight Binding Inhibitor of the Human Kinesin Eg5 That Specifically Blocks Mitotic Progression
14. Molecular Dissection of the Inhibitor Binding Pocket of Mitotic Kinesin Eg5 Reveals Mutants that Confer Resistance to Antimitotic Agents
15. Automated Analysis of Vapor Diffusion Crystallization Drops with an X-Ray Beam
16. Crystal Structure of the Motor Domain of the Human Kinetochore Protein CENP-E
17. Design and synthesis of novel thiadiazole-thiazolone hybrids as potential inhibitors of the human mitotic kinesin Eg5
18. The Overall Conformation of Conventional Kinesins Studied by Small Angle X-ray and Neutron Scattering
19. Conformation of the Drosophila Motor Protein Non-claret Disjunctional in Solution from X-ray and Neutron Scattering
20. The crystal structure of the minus-end-directed microtubule motor protein ncd reveals variable dimer conformations
21. Corrigendum to “Design and synthesis of novel thiadiazole-thiazolone hybrids as potential inhibitors of the human mitotic kinesin Eg5 [Bioorg Med Chem Lett 28 (17) (2018) 2930–2938]”
22. Crystallization and Preliminary X-Ray Analysis of the Single-Headed and Double-Headed Motor Protein Kinesin
23. A model of the microtubule–kinesin complex based on electron cryomicroscopy and X-ray crystallography
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