50 results on '"DePinho, Ronald A."'
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2. Telomere dysfunction alters intestinal stem cell dynamics to promote cancer
3. Elimination of oncogenic KRAS in genetic mouse models eradicates pancreatic cancer by inducing FAS-dependent apoptosis by CD8+ T cells
4. FoxO1 regulates leptin-induced mood behavior by targeting tyrosine hydroxylase
5. Collateral Lethality: A New Therapeutic Strategy in Oncology
6. Targeting Cathepsin E in Pancreatic Cancer by a Small Molecule Allows In Vivo Detection
7. Adiponectin Regulates Bone Mass via Opposite Central and Peripheral Mechanisms through FoxO1
8. Murine dendritic cell rapamycin-resistant and rictor-independent mTOR controls IL-10, B7-H1, and regulatory T-cell induction
9. IRS2 Signaling in LepR-b Neurons Suppresses FoxO1 to Control Energy Balance Independently of Leptin Action
10. FoxOs Integrate Pleiotropic Actions of Insulin in Vascular Endothelium to Protect Mice from Atherosclerosis
11. Lung Cancer Signatures in Plasma Based on Proteome Profiling of Mouse Tumor Models
12. Proinvasion Metastasis Drivers in Early-Stage Melanoma Are Oncogenes
13. FoxO1 Is a Positive Regulator of Bone Formation by Favoring Protein Synthesis and Resistance to Oxidative Stress in Osteoblasts
14. FoxO-Mediated Defense against Oxidative Stress in Osteoblasts Is Indispensable for Skeletal Homeostasis in Mice
15. FoxOs Enforce a Progression Checkpoint to Constrain mTORC1-Activated Renal Tumorigenesis
16. PLAGL2 Regulates Wnt Signaling to Impede Differentiation in Neural Stem Cells and Gliomas
17. Context-Dependent Transformation of Adult Pancreatic Cells by Oncogenic K-Ras
18. Inactivation of Hepatic Foxo1 by Insulin Signaling Is Required for Adaptive Nutrient Homeostasis and Endocrine Growth Regulation
19. Impaired Regulation of Hepatic Glucose Production in Mice Lacking the Forkhead Transcription Factor Foxo1 in Liver
20. The Differentiation and Stress Response Factor XBP-1 Drives Multiple Myeloma Pathogenesis
21. The PTEN and INK4A/ARF tumor suppressors maintain myelolymphoid homeostasis and cooperate to constrain histiocytic sarcoma development in humans
22. High-resolution genomic profiles define distinct clinico-pathogenetic subgroups of multiple myeloma patients
23. Block of T cell development in P53-deficient mice accelerates development of lymphomas with characteristic RAG-dependent cytogenetic alterations
24. Pten constrains centroacinar cell expansion and malignant transformation in the pancreas
25. Telomeres and the DNA damage response: why the fox is guarding the henhouse
26. Absence of telomerase and shortened telomeres have minimal effects on skin and pancreatic carcinogenesis elicited by viral oncogenes
27. The LKB1 tumor suppressor negatively regulates mTOR signaling
28. Endogenous oncogenic K-ras G12D stimulates proliferation and widespread neoplastic and developmental defects
29. Take care of your chromosomes lest cancer take care of you
30. Telomere dysfunction provokes regional amplification and deletion in cancer genomes
31. Epidermal growth factor receptor and Ink4a/Arf: Convergent mechanisms governing terminal differentiation and transformation along the neural stem cell to astrocyte axis
32. Analysis of C-MYC Function in Normal Cells via Conditional Gene-Targeted Mutation
33. Telomere Dysfunction-Induced DNA Damage Drives Hematopoietic Stem Cell Fate
34. Adiponectin Regulates Bone Mass via Opposite Central and Peripheral Mechanisms through FoxO1
35. Leukemogenic Transformation of Hematopoietic Cells by Constitutive Activation of Canonical Wnt Signaling in Osteoblast Precursors
36. Telomerase is required to slow telomere shortening and extend replicative lifespan of HSCs during serial transplantation
37. Proinvasion Metastasis Drivers in Early-Stage Melanoma Are Oncogenes
38. Foreword
39. Forkhead Box O (FoxO) Transcription Factors in the Actions of 1,25-Dihydroxyvitamin D 3 on Osteoblasts
40. 412 Neuroplastic Changes in a Mouse Model of Pancreatic Ductal Adenocarcinoma (PDAC)
41. p16INK4a Is a Key Downstream Mediator of the Deleterious Effects of FoxO Deficiency on Maintenance of the Hematopoietic Stem Cell Compartment.
42. Upregulation of c-Jun Induces Cell Death Via Caspase-Triggered c-Abl Cleavage in Human Multiple Myeloma.
43. Large Scale Copy Number Variation Upregulates the Expression of MYB in Human T-ALL.
44. The PTEN and INK4A/ARF tumor suppressors maintain myelolymphoid homeostasis and cooperate to constrain histiocytic sarcoma development in humans
45. The Role of Forkhead Transcription Factors FoxO1, FoxO3 and FoxO4 in Hematopoiesis and Leukemogenesis.
46. Targeted Overexpression of the Transcription Factor XBP-1 in B Cells Promotes Plasma Cell and Lymphoplasmacytic Neoplasms in Transgenic Mice.
47. Comprehensive Genome-Wide Profile of Regional Gains and Losses in Multiple Myeloma Using Array-CGH: The 1q21 Amplification and Potential Role of the BCL-9 Gene in Multiple Myeloma Pathogenesis.
48. Suppression of mouse colon tumor angiogenesis by the INK4a/ARF locus
49. Azathioprine and the liver: Evidence favoring idiosyncratic, mixed cholestatic-hepatocellular injury in humans
50. The familial melanoma gene, INK4a, cooperates with activated RAS in development of melanoma: A mouse model
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