112 results on '"Amidon, Gordon L."'
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2. A proposed pediatric biopharmaceutical classification system for medications for chronic diseases in children
3. The in vivo predictive dissolution for immediate release dosage of donepezil and danazol, BCS class IIc drugs, with the GIS and the USP II with biphasic dissolution apparatus
4. Effect of biphenyl hydrolase-like (BPHL) gene disruption on the intestinal stability, permeability and absorption of valacyclovir in wildtype and Bphl knockout mice
5. Gastric emptying and intestinal appearance of nonabsorbable drugs phenol red and paromomycin in human subjects: A multi-compartment stomach approach
6. Evaluation and optimized selection of supersaturating drug delivery systems of posaconazole (BCS class 2b) in the gastrointestinal simulator (GIS): An in vitro-in silico-in vivo approach
7. The Combination of GIS and Biphasic to Better Predict In Vivo Dissolution of BCS Class IIb Drugs, Ketoconazole and Raloxifene
8. Mechanistic Basis of Cocrystal Dissolution Advantage
9. The impact of supersaturation level for oral absorption of BCS class IIb drugs, dipyridamole and ketoconazole, using in vivo predictive dissolution system: Gastrointestinal Simulator (GIS)
10. The Evaluation of In Vitro Drug Dissolution of Commercially Available Oral Dosage Forms for Itraconazole in Gastrointestinal Simulator With Biorelevant Media
11. Carrier-Mediated Prodrug Uptake to Improve the Oral Bioavailability of Polar Drugs: An Application to an Oseltamivir Analogue
12. In Vivo Predictive Dissolution: Comparing the Effect of Bicarbonate and Phosphate Buffer on the Dissolution of Weak Acids and Weak Bases
13. In vitro dissolution methodology, mini-Gastrointestinal Simulator (mGIS), predicts better in vivo dissolution of a weak base drug, dasatinib
14. In Vivo Predictive Dissolution: Transport Analysis of the CO2, Bicarbonate In Vivo Buffer System
15. Evaluation of a Three Compartment In Vitro Gastrointestinal Simulator Dissolution Apparatus to Predict In Vivo Dissolution
16. The Biopharmaceutics Classification System: Subclasses for in vivo predictive dissolution (IPD) methodology and IVIVC
17. Bio-predictive tablet disintegration: Effect of water diffusivity, fluid flow, food composition and test conditions
18. Biowaiver Monographs for Immediate-Release Solid Oral Dosage Forms: Codeine Phosphate
19. The development of orally administrable gemcitabine prodrugs with d-enantiomer amino acids: Enhanced membrane permeability and enzymatic stability
20. Summary of the National Institute of Child Health and Human Development–Best Pharmaceuticals for Children Act Pediatric Formulation Initiatives Workshop–Pediatric Biopharmaceutics Classification System Working Group
21. The achievement of mass balance by simultaneous quantification of floxuridine prodrug, floxuridine, 5-fluorouracil, 5-dihydrouracil, α-fluoro-β-ureidopropionate, α-fluoro-β-alanine using LC–MS
22. The Solubility–Permeability Interplay in Using Cyclodextrins as Pharmaceutical Solubilizers: Mechanistic Modeling and Application to Progesterone
23. Puromycin-sensitive aminopeptidase: An antiviral prodrug activating enzyme
24. Corrigendum to ‘A proposed pediatric biopharmaceutical classification system for medications for chronic diseases in children’ [European Journal of Pharmaceutical Sciences 152 (2020) 105437]
25. Segmental-dependent membrane permeability along the intestine following oral drug administration: Evaluation of a triple single-pass intestinal perfusion (TSPIP) approach in the rat
26. Interferon-γ increases expression of the di/tri-peptide transporter, h-PEPT1, and dipeptide transport in cultured human intestinal monolayers
27. Quasi-equilibrium analysis of the ion-pair mediated membrane transport of low-permeability drugs
28. Particle diffusional layer thickness in a USP dissolution apparatus II: A combined function of particle size and paddle speed
29. Molecular Basis of Prodrug Activation by Human Valacyclovirase, an α-Amino Acid Ester Hydrolase
30. Mechanistic understanding of time-dependent oral absorption based on gastric motor activity in humans
31. Characteristics of Gastrointestinal Absorption of DX-9065a, a New Synthetic Anticoagulant
32. Comparative gene expression profiles of intestinal transporters in mice, rats and humans
33. Proline prodrug of melphalan, prophalan- l, demonstrates high therapeutic index in a murine melanoma model
34. Solubilization and dissolution of insoluble weak acid, ketoprofen: Effects of pH combined with surfactant
35. Nucleoside Ester Prodrug Substrate Specificity of Liver Carboxylesterase
36. Amino Acid Ester Prodrugs of 2-Bromo-5,6-dichloro-1-(β-d-ribofuranosyl)benzimidazole Enhance Metabolic Stability in Vitro and in Vivo
37. Pharmacokinetics of an immediate release, a controlled release and a two pulse dosage form in dogs
38. Cidofovir peptide conjugates as prodrugs
39. Surfactant-mediated dissolution: Contributions of solubility enhancement and relatively low micelle diffusivity
40. Effect of Experimental Acute Renal and Hepatic Failure on Absorption of Tacrolimus in Rat Small Intestine
41. Oral absorption of phytosterols and emulsified phytosterols by Sprague-Dawley rats
42. Identification of a Human Valacyclovirase: BIPHENYL HYDROLASE-LIKE PROTEIN AS VALACYCLOVIR HYDROLASE
43. Polymer degradation and in vitro release of a model protein from poly( d, l-lactide- co-glycolide) nano- and microparticles
44. Functional expression and characterization of a sodium-dependent nucleoside transporter hCNT2 cloned from human duodenum
45. Improved Intestinal Transport of PD 158473, an N-methyl-d-Aspartate (NMDA) Antagonist, by Involvement of Multiple Transporters
46. Intestinal Metabolism and Absorption of Cholecystokinin Analogs in Rats
47. Tacrolimus is a class II low-solubility high-permeability drug: The effect of P-glycoprotein efflux on regional permeability of tacrolimus in rats
48. Variability in cimetidine absorption and plasma double peaks following oral administration in the fasted state in humans: correlation with antral gastric motility
49. Possible degradative process of cholecystokinin analogs in rabbit jejunum brush-border membrane vesicles
50. Novel method to assess gastric emptying in humans: the Pellet Gastric Emptying Test
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