1. Short-Pulse Lasers: A Versatile Tool in Creating Novel Nano-/Micro-Structures and Compositional Analysis for Healthcare and Wellbeing Challenges
- Author
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Frédérique Magdinier, Patricia Alloncle, Jörg Hermann, Ahmed Al-Kattan, Vincent Motto-Ros, David Grojo, Philippe Delaporte, Alexandros Mouskeftaras, Christophe Drouet, Adrien Casanova, Catalin Constantinescu, Jérôme D. Robin, Gall, Valérie, Extreme-Light Seeded Control of Ultrafast Laser Material Modifications - EXSEED - - European Union’s Horizon 2020 research and innovation program2017-05-01 - 2022-04-30 - 724480 - VALID, Laboratoire Lasers, Plasmas et Procédés photoniques (LP3), Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS), Centre interuniversitaire de recherche et d'ingenierie des matériaux (CIRIMAT), Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées, Marseille medical genetics - Centre de génétique médicale de Marseille (MMG), Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM), Spectrométrie des biomolécules et agrégats (SPECTROBIO), Institut Lumière Matière [Villeurbanne] (ILM), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS), European Project: 724480,European Union’s Horizon 2020 research and innovation program,EXSEED(2017), Centre National de la Recherche Scientifique (CNRS)-Aix Marseille Université (AMU), Centre National de la Recherche Scientifique (CNRS)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Institut de Chimie du CNRS (INC), Institut National de la Santé et de la Recherche Médicale (INSERM)-Aix Marseille Université (AMU), Centre National de la Recherche Scientifique (CNRS)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon, Université de Toulouse (UT)-Université de Toulouse (UT)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP), and Université de Toulouse (UT)
- Subjects
[SDV.BIO]Life Sciences [q-bio]/Biotechnology ,laser-assisted methods ,Computer science ,General Chemical Engineering ,[SDV]Life Sciences [q-bio] ,Nanotechnology ,Review ,02 engineering and technology ,Surface engineering ,01 natural sciences ,Structuring ,law.invention ,lcsh:Chemistry ,Machining ,law ,General Materials Science ,laser printing ,Flexibility (engineering) ,[SDV.IB] Life Sciences [q-bio]/Bioengineering ,Laser ablation ,Laser printing ,010401 analytical chemistry ,021001 nanoscience & nanotechnology ,Laser ,laser elemental analysis ,nanomedicine ,3. Good health ,0104 chemical sciences ,[SDV.BIO] Life Sciences [q-bio]/Biotechnology ,[SDV] Life Sciences [q-bio] ,lcsh:QD1-999 ,13. Climate action ,tissue engineering ,laser machining ,Nanomedicine ,[SDV.IB]Life Sciences [q-bio]/Bioengineering ,nanoparticles ,0210 nano-technology - Abstract
International audience; Driven by flexibility, precision, repeatability and eco-friendliness, laser-based technologies have attracted great interest to engineer or to analyze materials in various fields including energy, environment, biology and medicine. A major advantage of laser processing relies on the ability to directly structure matter at different scales and to prepare novel materials with unique physical and chemical properties. It is also a contact-free approach that makes it possible to work in inert or reactive liquid or gaseous environment. This leads today to a unique opportunity for designing, fabricating and even analyzing novel complex bio-systems. To illustrate this potential, in this paper, we gather our recent research on four types of laser-based methods relevant for nano-/micro-scale applications. First, we present and discuss pulsed laser ablation in liquid, exploited today for synthetizing ultraclean “bare” nanoparticles attractive for medicine and tissue engineering applications. Second, we discuss robust methods for rapid surface and bulk machining (subtractive manufacturing) at different scales by laser ablation. Among them, the microsphere-assisted laser surface engineering is detailed for its appropriateness to design structured substrates with hierarchically periodic patterns at nano-/micro-scale without chemical treatments. Third, we address the laser-induced forward transfer, a technology based on direct laser printing, to transfer and assemble a multitude of materials (additive structuring), including biological moiety without alteration of functionality. Finally, the fourth method is about chemical analysis: we present the potential of laser-induced breakdown spectroscopy, providing a unique tool for contact-free and space-resolved elemental analysis of organic materials. Overall, we present and discuss the prospect and complementarity of emerging reliable laser technologies, to address challenges in materials’ preparation relevant for the development of innovative multi-scale and multi-material platforms for bio-applications.
- Published
- 2021
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