1. The EPTN consensus-based atlas for CT- and MR-based contouring in neuro-oncology
- Author
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Eekers, Daniëlle Bp, In T Ven, Lieke, Roelofs, Erik, Postma, Alida, Alapetite, Claire, Burnet, Neil G., Valentin CALUGARU, Compter, Inge, Coremans, Ida E. M., Høyer, Morton, Lambrecht, Maarten, Nyström, Petra Witt, Méndez Romero, Alejandra, Paulsen, Frank, Perpar, Ana, Ruysscher, Dirk, Renard, Laurette, Timmermann, Beate, Vitek, Pavel, Weber, Damien C., Weide, Hiske L., Whitfield, Gillian A., Wiggenraad, Ruud, Troost, Esther G. C., Estro, 'european Particle Therapy Network' Of, RS: GROW - R3 - Innovative Cancer Diagnostics & Therapy, Radiotherapie, Promovendi ODB, Beeldvorming, MUMC+: DA BV Medisch Specialisten Radiologie (9), UCL - SSS/IREC/SLUC - Pôle St.-Luc, UCL - (SLuc) Service de radiothérapie oncologique, and Radiotherapy
- Subjects
Organs at Risk ,Neuro oncology ,medicine.medical_treatment ,Tomography, X-Ray Computed/methods ,Medizin ,030218 nuclear medicine & medical imaging ,Magnetic Resonance Imaging/methods ,0302 clinical medicine ,NECK-CANCER ,European Particle Therapy Network ,NASOPHARYNGEAL CARCINOMA ,Proton Therapy ,Radiation oncologist ,Contouring ,NEUROCOGNITIVE FUNCTION ,medicine.diagnostic_test ,Manchester Cancer Research Centre ,Brain Neoplasms ,Atlas for neuro-oncology ,Hematology ,Magnetic Resonance Imaging ,CRANIAL IRRADIATION ,Organs at risk ,medicine.anatomical_structure ,Oncology ,030220 oncology & carcinogenesis ,Radiology, Nuclear Medicine and Medical Imaging ,WHOLE-BRAIN RADIOTHERAPY ,Consensus ,PROTON THERAPY ,Brain Neoplasms/radiotherapy ,Particle therapy ,Heavy Ion Radiotherapy ,03 medical and health sciences ,Atlas (anatomy) ,medicine ,Journal Article ,Humans ,Radiology, Nuclear Medicine and imaging ,RADIATION ONCOLOGISTS GUIDE ,HEAD ,Radiometry ,Proton therapy ,Radiotherapy Planning, Computer-Assisted/methods ,Cancer och onkologi ,business.industry ,Radiotherapy Planning, Computer-Assisted ,ResearchInstitutes_Networks_Beacons/mcrc ,HEARING-LOSS ,Magnetic resonance imaging ,Sagittal plane ,INTENSITY-MODULATED RADIOTHERAPY ,Cancer and Oncology ,Radiologi och bildbehandling ,business ,Nuclear medicine ,Tomography, X-Ray Computed - Abstract
PURPOSE: To create a digital, online atlas for organs at risk (OAR) delineation in neuro-oncology based on high-quality computed tomography (CT) and magnetic resonance (MR) imaging. METHODS: CT and 3 Tesla (3T) MR images (slice thickness 1 mm with intravenous contrast agent) were obtained from the same patient and subsequently fused. In addition, a 7T MR without intravenous contrast agent was obtained from a healthy volunteer. Based on discussion between experienced radiation oncologists, the clinically relevant organs at risk (OARs) to be included in the atlas for neuro-oncology were determined, excluding typical head and neck OARs previously published. The draft atlas was delineated by a senior radiation oncologist, 2 residents in radiation oncology, and a senior neuro-radiologist incorporating relevant available literature. The proposed atlas was then critically reviewed and discussed by European radiation oncologists until consensus was reached. RESULTS: The online atlas includes one CT-scan at two different window settings and one MR scan (3T) showing the OARs in axial, coronal and sagittal view. This manuscript presents the three-dimensional descriptions of the fifteen consensus OARs for neuro-oncology. Among these is a new OAR relevant for neuro-cognition, the posterior cerebellum (illustrated on 7T MR images). CONCLUSION: In order to decrease inter- and intra-observer variability in delineating OARs relevant for neuro-oncology and thus derive consistent dosimetric data, we propose this atlas to be used in photon and particle therapy. The atlas is available online at www.cancerdata.org and will be updated whenever required. ispartof: RADIOTHERAPY AND ONCOLOGY vol:128 issue:1 pages:37-43 ispartof: location:Ireland status: published
- Published
- 2018
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