Search

Your search keyword '"di Grazia, C."' showing total 97 results
Start Over Author "di Grazia, C." Database OpenAIRE
97 results on '"di Grazia, C."'

2. Enhancing the diagnosis of maxillary transverse discrepancy through 3-D technology and surface-to-surface superimposition. Description of the digital workflow with a documented case report

Author

Lo Giudice, A, Nucera, R, Ronsivalle, V, Di Grazia, C, Rugeri, M, and Quinzi, V

Subjects
Palatal Expansion Technique, Surface-to-surface superimposition, Maxilla, Humans, Female, Digital work-flow, Maxillary transverse discrepancy, 3-D technology, Child, Workflow, Malocclusion
Abstract

Maxillary transverse discrepancy is often diagnosed in childhood. The evaluation of morphological characteristics of the maxilla is crucial for appropriate treatment of this condition, however conventional diagnostic method is based on visual inspection and transversal linear parameters. In this paper, we described a user-friendly diagnostic digital workflow based on the surface-to-surface analysis. We also described a case report.A 6-year-old female patient presenting mild transversal maxillary deficiency associated with functional posterior crossbite was treated by using maxillary removable appliance. In this respect, the appliance was designed in accordance to the morphological characteristics of the maxilla obtained by using the diagnostic digital work-flow and the maxillary surface-to-surface analysis.The present user-friendly diagnostic digital workflow based on surface-to-surface analysis helps clinicians to detect specific morphological characteristics of the maxilla, such as shape and area of asymmetry, in order to reach a comprehensive diagnosis and choose the correct biomechanics for treating the condition.

Published
2020

3. Small bowel intussussception due to metastatic melanoma of unknown primary site. Case report

Author

STAGNITTI, F., ORSINI, S., MARTELLUCCI, A., TUDISCO, A., AVALLONE, M., AIUTI, F., DI GIROLAMO, V., STEFANELLI, F., DE ANGELIS, F., COSTANTINO, A., DI GRAZIA, C., NAPOLEONI, A., NICODEMI, S., CIPRIANI, B., CECI, F., MOSILLO, R., CORELLI, S., CASCIARO, G., and SPAZIANI, E.

Subjects
Male, Oncology, Pathology, medicine.medical_specialty, Ileum, Metastasis, Clinical Practice, Internal medicine, medicine, Humans, Malignant melanoma, Unknown primary, Intestinal intussusceptions, Disseminated disease, Melanoma, Gastrointestinal tract, business.industry, Middle Aged, medicine.disease, Ileal Neoplasms, medicine.anatomical_structure, Iron-deficiency anemia, Neoplasms, Unknown Primary, Segmental resection, business, Intestinal Obstruction, Brain metastasis
Abstract

Malignant melanoma is characterized by metastases also to the gastrointestinal tract, especially in the small bowel. The diagnosis is often delayed because unspecific clinical presentation (frequently as chronic iron deficiency anemia, rectal bleeding or intestinal obstruction). We present a case of melanoma of unknown primary site, with clinical presentation of intestinal obstruction. A segmental resection of the ileum was performed including mesentery with lymph nodes. Histology revealed metastatic melanoma from unknown primary. PET and MRI confirmed disseminated disease without brain metastasis.

Published
2014

4. Biliodigestive fistulae and gallstone ileus;diagnostic and therapeutic considerations. Our experience

Author

F. Stefanelli, Spaziani E, A. Costantino, Andrea Napoleoni, Tudisco A, S. Nicodemi, De Angelis F, Di Grazia C, Ceci F, Orsini S, M. Avallone, B. Cipriani, Di Girolamo, F. Aiuti, Franco Stagnitti, Corelli S, Mosillo R, Martellucci A, and G E Casciaro

Subjects
Past medical history, medicine.medical_specialty, business.industry, Fistula, medicine.medical_treatment, General surgery, fistulae, gallstone, Context (language use), medicine.disease, Bowel obstruction, Gallstone ileus, Cholecystitis, medicine, ileus, Cholecystectomy, business, Complication
Abstract

The biliodigestive fistula is not a rare affection in the context of acute pathology of the gastrointestinal tract. It often affects patients between 63 and 85 years old , particularly the female sex, and the most common cause is acute or chronic cholecystolithiasis. Open issues are the delayed in the pre-operative diagnosis, and controversies exist regarding the best surgical approach. The choice of treatment options is influenced by the age of the patients and their clinical conditions and also by the presence of comorbidities and of a delayed right diagnosis. In the 1 to 3% of cases, the biliodigestive fistula presents a gallstone ileus as complication, whose diagnosis is particularly difficult for the lack of specific signs and symptoms. The contrast-enhanced CT is considered the gold standard for a specific pre-operative diagnosis, as it directly shows the fistula. Surgical treatments include one-stage procedure or two-stage procedure. Many studies seem to favor a deferred definitive procedure. The Authors describe 4 cases: in 3 cases, women between 70 and 80 years old presenting an history of recurrent cholecystitis, in 2 cases, and in 1 case presenting a bowel obstruction; in 1 case a 50-years-old man, with no significant past medical history, presenting a bowel obstruction. The Authors have performed in the 2 cases of gallstone ileus an enterolithotomy with cholecysto-duodenal fistula repair and cholecystectomy, in one-stage, and this has been possible because of the good clinical conditions of the patients and their low operative risk. In the case of fistula without the complication of gallstone ileus, the treatment approach has been cholecysto-gastric fistula closure with a gastroplastic using separate stitches and cholecystectomy, in one-stage. We are in agreement with data in the literature regarding the delay into the diagnosis of biliodigestive fistula and with the importance to suspect it or gallstone ileus presence, although the clinical presentation is extremely non-specific. In our experience, cholangiopancreatography-CT and CECT have made easier the pre-operative diagnosis and so reducing the delay of the treatment.

Published
2014

5. Risk management in surgery

Author

Messano, GIUSEPPE ALESSIO, Spaziani, Erasmo, Turchetta, F., Ceci, F., Corelli, S., Casciaro, Giovanni Enrico, Martellucci, A., Costantino, A., Napoleoni, A., Cipriani, B., Nicodemi, S., Di Grazia, C., Mosillo, R., Avallone, M., Orsini, S., Tudisco, A., Aiuti, F., and Stagnitti, Franco

Subjects
antibiotic therapy, laparoscopic drainage, liver abscesses, percutaneous drainage, risk management, Risk Management, Italy, Surgical Procedures, Operative, Humans, Focus on, Checklist
Abstract

Malpractice is the responsible for the greatest number of legal claims. At the present time, legal actions against physicians in Italy are 15,000 per year, and a stunning increase about costs to refund patients injured by therapeutic and diagnostic errors is expected. The method for the medical prevention is “Risk Management”, that is the setting-up of organizational instruments, methods and actions that enable the measurement or estimation of medical risk; it allows to develop strategies to govern and reduce medical error. In the present work, the reconstruction about the history of risk management in Italy was carried out. After then the latest initiatives undertaken by Italy about the issue of risk management were examined.

Published
2013

8. High prevalence of hepatitis G virus infection in Hodgkin's disease and B-cell lymphoproliferative disorders: Absence of correlation with hepatitis C virus infection

Author

Renzo, A., Persico, E., Marino, F., Di Giacomo Russo, G., Rosario Notaro, Di Grazia, C., Picardi, M., Santoro, L., Torella, R., Rotoli, B., Persico, M., DE RENZO, A., Persico, E., DE MARINO, F., DI GIACOMO RUSSO, G., Notaro, R., DI GRAZIA, C., Picardi, Marco, Santoro, L., Torella, R., Rotoli, Bruno, and Persico, M.

Subjects
Hodgkin disease, adult, correlation analysis, prevalence, article, major clinical study, aged, carcinogenesis, comorbidity, controlled study, female, hepatitis C, hepatitis G, human, lymphoproliferative disease, male

37. Reducing transplant-related mortality after allogeneic hematopoietic stem cell transplantation

Author

Bacigalupo, A., Sormani, M. P., Lamparelli, T., Gualandi, F., Occhini, D., Bregante, S., ANNA MARIA RAIOLA, Di Grazia, C., Dominietto, A., Tedone, E., Piaggio, G., Podesta, M., Bruno, B., Oneto, R., Lombardi, A., Frassoni, F., Rolla, D., Rollandi, G., Viscoli, C., Ferro, C., Garbarino, L., and Lint, M. T.

Subjects
Adult, Male, Neutropenia, Transplantation Conditioning, Multiple Organ Failure, Premedication, Graft vs Host Disease, Infections, Anti-Infective Agents, Actuarial Analysis, Cause of Death, Antineoplastic Combined Chemotherapy Protocols, Humans, Transplantation, Homologous, Bone Marrow Transplantation, Retrospective Studies, Salvage Therapy, Infection Control, Peripheral Blood Stem Cell Transplantation, Leukemia, Remission Induction, Hematopoietic Stem Cell Transplantation, Middle Aged, Combined Modality Therapy, Survival Analysis, Treatment Outcome, Hematologic Neoplasms, Female, Lung Diseases, Interstitial, Immunosuppressive Agents
Abstract

Transplant-related mortality (TRM) following allogeneic hematopoietic stem cell transplantation (HSCT) has been reported to be related to disease stage, duratiion of disease and type of donor. Furthermore, the outcome of transplants performed in the 1990s appears to be better than that of transplants done in the previous decade. The aims of this study were to determine whether these relationships still hold and whether the outcome of transplants is continuing to improve.We analyzed 1180 consecutive patients with leukemia (n=979) or other hematologic malignancies (n=201) undergoing HSCT in 4 time periods: before 1990, 1991-1995, 1996-2000, and 2001-2002. Changes during these eras include increasing patient age, more unrelated transplants, more patients with advanced disease, different graft-versus-host disease (GvHD) prophylaxis, and different management of infections.The actuarial 2-year transplant-related mortality (TRM) differed significantly between the transplant eras (p0.001) with a significant interaction with disease phase (p=0.018). In patients in first remission (n=585) TRM was 34%, 25%, 21% and 6% in the four transplant eras. The reduction in TRM was less evident in patients in second remission (n=284) (37%, 35%, 30%, 25%) and absent in relapsed patients (n=311) (TRM=45%, 41%, 29%, 51%). This is a consequence of reductions in GvHD, infections and multiorgan failure among patients in remission but not among those who relapse. The actuarial 2-year survival has improved significantly in patients in first remission (54%, 66%, 72%, 78%) but not in those in second remission (38%, 46%, 52%,45%), or relapsed patients (31%, 25%, 36%, 21%).In conclusion, TRM has been significantly reduced in first remission patients, suggesting an allograft should be considered in this phase, when appropriate, without delay. There has been no improvement in survival for patients beyond first remission, due to persisting high risk of infections and organ toxicity, a possible consequence of prolonged pre-transplant chemotherapy and neutropenia.

Catalog

Books, media, physical & digital resources
See catalog results