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Made available in DSpace on 2022-04-29T07:26:33Z (GMT). No. of bitstreams: 0 Previous issue date: 2015-11-24 Background: During almost one-third of our life, maturation of the nervous system promotes strength and muscle mass increase. However, as age advances, the nervous system begins to suffer a slow and continue reduction of its functions. Neuromuscular junction (NMJ) is one of the structures of which change due to aging process. Physical training leads to significant adjustments in NMJs of young and aged animals. Nevertheless, studies that aimed to investigate this effect have, in many cases, methodological variables that may have some influence on the result. Thus, this study aimed to carry out a systematic review about the effects of exercise training on the NMJ compartments of young, adult and aged animals. Results: We searched PubMed, Google Scholar, Science Direct, Scielo and Lilacs databases for animal experimental studies that studied exercise effects on the NMJs components across age. After inclusion and exclusion criteria, we included nine articles in systematic review and two for meta-analysis (young/adult NMJ). Conclusions: We identified that exercise training cause NMJ hypertrophy on young animals and NMJ compression on aged ones. However, many methodological issues such as age, skeletal muscle and fibers type, and type of exercise and training protocol might influence the results. Laboratory of Morphoquantitative Studies and Immunohistochemistry Physical Education Department São Judas Tadeu University, Unidade Mooca, Rua Taquari, 546, Mooca Laboratory of Histology and Electron Microscopy Physical Education Department Julio de Mesquita Filho São Paulo State University Laboratory of Histology and Electron Microscopy Physical Education Department Julio de Mesquita Filho São Paulo State University

The objective of this work was to determine the effects of combined exercise training on the left ventricle (LV) weight, wall thickness and cavity dimension in rats. One group of rats were submitted to this type of exercise. Exercise training was performed 7 times weekly for 8 weeks. A sedentary control group (C) was included. The values of the LV weight increased 7.5% in the combined exercise training group (RA) (P < 0.05), compared with the C group and the LV wall thickness increased 8% in the RA group, (P