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Background: Thyroid hormones play an important role in cardiac tissue function. Therefore, it is important to understand the relationship between thyroid hormone levels and cardiac disorders. Objectives: The present study aimed to assess the relationship between normal serum level of thyroid hormones and left ventricular systolic and diastolic dysfunction. Methods: In this cross sectional descriptive retrospective study, 391 patients were selected. They were referred to the Rajaie Cardiovascular Research Center, Tehran, Iran from 2019 to 2021. After extracting echocardiographic and laboratory data from the clinical records, the parameters affecting the left ventricular systolic and diastolic dysfunction were analyzed using statistical software. Results: The mean age of patients was 41 ± 12.8 years. Among them 58.1% of all patients were female. Tricuspid regurgitation (TR) severity had a significant relationship with thyroid stimulating hormone (TSH) level (P = 0.02). End diastolic interventricular septum thickness (IVSD) was inversely associated with thyroxin4 (T4) level (P = 0.04). Mitral valve inflow deceleration time (MVDT) was inversely correlated with thyroxin3 (T3) (P = 0.04). Left ventricular ejection fraction (LVEF) was inversely related to TSH level and end diastolic right ventricular internal diameter (RVIDd) was directly related to TSH (P = 0.05). Conclusions: Thyroid hormone levels in the normal range can be associated with the tricuspid regurgitation severity, end diastolic right ventricular internal diameter (RVIDd), mitral valve inflow deceleration time (MVDT), and. end diastolic interventricular septum thickness (IVSD). Due to the high prevalence of heart disorders, information on thyroid hormone levels can be helpful in the identification and timely treatment of these disorders.

Purpose LV diastolic dysfunction has often been described as a sensitive sign of early graft rejection. Assessment of left ventricular filling pressure by echocardiography in heart transplant (HTx) recipients is challenging. We aimed to investigate the ability of echocardiographic indices to detect elevated Left ventricular end-diastolic pressure (LVEDP) in HTx patients. Methods This descriptive cross-sectional study included 39 HTx recipients who were candidates for endomyocardial biopsy as a part of their routine post-transplantation surveillance. Doppler transthoracic echocardiography was done before the procedure, and left heart catheterization was done during the endomyocardial biopsy. Results Thirty-nine patients (15 female, 24 male), with the mean age of 39.6 years (range 13 to 70), were enrolled. A strong relation was observed between lateral E/e’ and LVEDP (R = 0.64, P-value

Cancer treatment approaches are greatly improved in recent years. Myxomas are the most frequent intracardiac neoplasm, accounting for nearly 50% of all benign tumors. The left atrium with 75% of cases and the right atrium with 20% of cases are the most common locations of myxomas. Atrial myxomas are benign, slow-growing neoplasms that arise from the interatrial septum and extend into the left or right atrium. Right atrial myxomas may present as right-sided heart failure and pulmonary embolism. Breast cancer is the second most common cause of death among women worldwide. Eight percent of patients are presented with distant metastases. A large number of breast tumors are not random events, and some of them are due to the human genome alteration. Mammary carcinoma is a common familial cancer, which is transmitted in an autosomal dominant manner. We have noticed that patients with breast cancer visiting our cardio-oncology department are occasionally presented with cardiac myxoma.