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Additional file 1. Individual correlations of CPO (W) vs. LVSW minâ â 1 (W). Cardiac Power Output (CPO) significantly reflects Left ventricular stroke work per minute (LV SW min-1) over a wide range of inotropic states in each experimental group (Group 1â 5). Groups are described as follows: a) group 1: resuscitation after ventricular fibrillation (RES); b) group 2: myocardial infarction by coronary microembolisation (CME); c) group 3: endotoxemia by LPS-infusion (LPS); d) group 4: sevoflurane-induced myocardial depression (SEVO); e) group 5: Temperature modulation from hyperthermia to mild hypothermia vs dobutamine (DOB). Any rise or fall of LV SW min-1 corresponds to an equivalent change of CPO.

Einleitung: Bei Frauen mit korrigierter Fallot-Tetralogie ist die Schwangerschaft mit Herz-, Schwangerschafts- und Geburtsproblemen verbunden. Die Ergebnisse nach einer Korrekturoperation waren in den letzten Jahrzehnten sehr gut und brachten eine lange Überlebensrate mit sich. Unser Ziel ist [for full text, please go to the a.m. URL], 131. Kongress der Deutschen Gesellschaft für Chirurgie

Einführung: Trotz laufender Verbesserung der medizinischen Ausbildung kommen viele Lehrinhalte der klinischen Praxis im Regelstudienplan zu kurz. Fehlende klinische Erfahrung sowie das Fehlen einer in jeder anderen Berufssparte üblichen strukturierten Einschulungs- und Einarbeitungsphase führen[for full text, please go to the a.m. URL], Jahrestagung der Gesellschaft für Medizinische Ausbildung (GMA)

Introduction: Pulmonary embolism (PE) is one of the leading causes of maternal mortality. Because of the Virchow’s triad (hypercoagulability, vascular damage and venous stasis) the venous thromboembolism risk during pregnancy is much higher. Material and methods: We present two different procedures,[for full text, please go to the a.m. URL], 130. Kongress der Deutschen Gesellschaft für Chirurgie

Introduction: Osteoprotegerin (OPG) is membrane bound in the immune system but can also be produced and secreted almost everywhere in the organism, so that it is mainly available in soluble form. So far, the OPG/RANKL/RANK system has been most intensively studied in bone. The binding of RANKL[for full text, please go to the a.m. URL], 130. Kongress der Deutschen Gesellschaft für Chirurgie

BACKGROUND: Cardiac power output (CPO), derived from the product of cardiac output and mean aortic pressure, is an important yet underexploited parameter for hemodynamic monitoring of critically ill patients in the intensive-care unit (ICU). The conductance catheter-derived pressure-volume loop area reflects left ventricular stroke work (LV SW). Dividing LV SW by time, a measure of LV SW min- 1 is obtained sharing the same unit as CPO (W). We aimed to validate CPO as a marker of LV SW min- 1 under various inotropic states. METHODS: We retrospectively analysed data obtained from experimental studies of the hemodynamic impact of mild hypothermia and hyperthermia on acute heart failure. Fifty-nine anaesthetized and mechanically ventilated closed-chest Landrace pigs (68 ± 1 kg) were instrumented with Swan-Ganz and LV pressure-volume catheters. Data were obtained at body temperatures of 33.0 °C, 38.0 °C and 40.5 °C; before and after: resuscitation, myocardial infarction, endotoxemia, sevoflurane-induced myocardial depression and beta-adrenergic stimulation. We plotted LVSW min- 1 against CPO by linear regression analysis, as well as against the following classical indices of LV function and work: LV ejection fraction (LV EF), rate-pressure product (RPP), triple product (TP), LV maximum pressure (LVPmax) and maximal rate of rise of LVP (LV dP/dtmax). RESULTS: CPO showed the best correlation with LV SW min- 1 (r2 = 0.89; p