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2. Infected pancreatic necrosis: outcomes and clinical predictors of mortality. A post hoc analysis of the MANCTRA-1 international study
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Podda, Mauro, Pellino, Gianluca, Di Saverio, Salomone, Coccolini, Federico, Pacella, Daniela, Cioffi, Stefano Piero Bernardo, Virdis, Francesco, Balla, Andrea, Ielpo, Benedetto, Pata, Francesco, Poillucci, Gaetano, Ortenzi, Monica, Damaskos, Dimitrios, De Simone, Belinda, Sartelli, Massimo, Leppaniemi, Ari, Jayant, Kumar, Catena, Fausto, Giuliani, Antonio, Di Martino, Marcello, Pisanu, Adolfo, Chiara Gerardi, Stavros Gourgiotis, Cristiana Riboni, Alessio Giordano, Luca Ferrario, Vanni Agnoletti, Yoram Kruger, Damian Mole, Ferdinando Agresta, Mikel Prieto Calvo, Michael Wilson, Fiammetta Soggiu, Alaa Hamdan, Carlos Augusto Gomes, Gustavo Fraga, Argyrios Ioannidis, Zaza Demetrashvili, Saaz Sahani, Lovenish Bains, Almu'atasim Khamees, Hazim Ababneh, Osama Aljaiuossi, Samuel Pimentel, Ikhwan Sani Mohamad, Ahmad Ramzi Yusoff, Narcis Octavian Zarnescu, Valentin Calu, Andrey Litvin, Dusan Lesko, Ahmed Elmehrath, Mohamedraed Elshami, Martin de Santibañes, Justin Gundara, Kamel Alawadhi, Rashid Lui, Alexander Julianov, Sergio Ralon, Ibrahim-Umar Garzali, Gustavo M Machain, Ibabe Villalabeitia, Darwin Artidoro Quispe-Cruz, Abigail Cheska C Orantia, Maciej Walędziak, Tiago Correia de Sá, Syed Muhammad Ali, Bojan Kovacevic, Colin Noel, Haidar M Abdalah, Ali Kchaou, Arda Isik, Luca Ansaloni, Walter Biffl, Mario Guerrieri, Alberto Sartori, Manuel Abradelo, Giuseppe Nigri, Nicola Di Lorenzo, Andrea Mingoli, Massimo Chiarugi, Juliana Di Menno Stavron, Oscar Mazza, José Ignacio Valenzuela, Diana Alejandra Pantoja Pachajoa, Fernando Andrés Alvarez, Julian Ezequiel Liaño, Joan Tefay, Abdulrahman Alshaikh, Layla Hasan, Felipe Couto Gomes, Thiago R A Calderan, Elcio S Hirano, Dragomir Dardanov, Azize Saroglu, Boyko Atanasov, Nikolay Belev, Nikola Kovachev, Shannon Melissa Chan, Hon-Ting Lok, Diego Salcedo, Diana Robayo, María Alejandra Triviño, Jan Manak, Jorann de Araujo, Ananya Sethi, Ahmed Awad, Merihan Elbadawy, Ahmed Farid, Asmaa Hanafy, Ahmed Nafea, Ghozy Sherief, Abbas Salah Alzhraa, Wafaa Abdelsalam, Sameh Emile, Ahmed Elfallal, Hossam Elfeki, Hosam Elghadban, Ashraf Shoma, Mohamed Shetiwy, Mohamed Elbahnasawy, Salem Mohamed, Emad Fawzi Hamed, Usama Ahmed Khalil, Elie Chouillard, Andrew Gumbs, Andrea Police, Andrea Mabilia, Kakhi Khutsishvili, Anano Tvaladze, Orestis Ioannidis, Elissavet Anestiadou, Lydia Loutzidou, Konstantinis Konstantinidis, Sofia Konstantinidou, Dimitrios Manatakis, Vasileios Acheimastos, Nikolaos Tasis, Nikolaos Michalopoulos, Panagiotis Kokoropoulos, Maria Papadoliopoulou, Maria Sotiropoulou, Stylianos Kapiris, Panagiotis Metaxas, Ioannis Tsouknidas, Despoina Kefili, George Petrakis, Eirini Synekidou, Konstantinos Dakis, Eirini Alexandridou, Aristeidis Papadopoulos, Christos Chouliaras, Odysseas Mouzakis, Francesk Mulita, Ioannis Maroulis, Michail Vailas, Tania Triantafyllou, Dimitrios Theodorou, Eftychios Lostoridis, Eleni-Aikaterini Nagorni, Paraskevi Tourountzi, Efstratia Baili, Alexandros Charalabopoulos, Theodore Liakakos, Dimitrios Schizas, Alexandros Kozadinos, Athanasios Syllaios, Nikolaos Machairas, Stylianos Kykalos, Paraskevas Stamopoulos, Spiros Delis, Christos Farazi-Chongouki, Evangelos Kalaitzakis, Miltiadis Giannarakis, Konstantinos Lasithiotakis, Giorgia Petra, Amit Gupta, Noushif Medappil, Vijayanand Muthukrishnan, Jubin Kamar, Pawan Lal, Rajendra Agarwal, Matteo Magnoli, Paolo Aonzo, Alberto Serventi, Pierpaolo Di Lascio, Margherita Pinto, Carlo Bergamini, Andrea Bottari, Laura Fortuna, Jacopo Martellucci, Atea Cicako, Claudio Miglietta, Mario Morino, Daniele Delogu, Andrea Picchetto, Marco Assenza, Giancarlo D'Ambrosio, Giulio Argenio, Mariano Fortunato Armellino, Giovanna Ioia, Savino Occhionorelli, Dario Andreotti, Lacavalla Domenico, Davide Luppi, Massimiliano Casadei, Luca Di Donato, Farshad Manoochehri, Tiziana Rita Lucia Marchese, William Sergi, Roberto Manca, Raimondo Murgia, Enrico Piras, Lorenzo Conti, Simone Gianazza, Andrea Rizzi, Edoardo Segalini, Marco Monti, Elena Iiritano, Nicolò Maria Mariani, Enrico De Nicola, Giovanna Scifo, Giusto Pignata, Jacopo Andreuccetti, Francesco Fleres, Guglielmo Clarizia, Alessandro Spolini, Alan Biloslavo, Paola Germani, Manuela Mastronardi, Selene Bogoni, Silvia Palmisano, Nicolo' De Manzini, Marco Vito Marino, Gennaro Martines, Giuseppe Trigiante, Elpiniki Lagouvardou, Gabriele Anania, Cristina Bombardini, Dario Oppici, Tiziana Pilia, Valentina Murzi, Emanuela Gessa, Umberto Bracale, Maria Michela Di Nuzzo, Roberto Peltrini, Francesco Salvetti, Jacopo Viganò, Gabriele Sganga, Valentina Bianchi, Pietro Fransvea, Tommaso Fontana, Giuliano Sarro, Vincenza Paola Dinuzzi, Luca Scaravilli, Mario Virgilio Papa, Elio Jovine, Giulia Ciabatti, Laura Mastrangelo, Matteo Rottoli, Claudio Ricci, Iris Shari Russo, Alberto Aiolfi, Davide Bona, Francesca Lombardo, Pasquale Cianci, Mariagrazia Sederino, Roberto Bini, Osvaldo Chiara, Stefano Cioffi, Stefano Cantafio, Guido Coretti, Edelweiss Licitra, Grazia Savino, Sergio Grimaldi, Raffaele Porfidia, Elisabetta Moggia, Mauro Garino, Chiara Marafante, Antonio Pesce, Nicolò Fabbri, Carlo Vittorio Feo, Ester Marra, Marina Troian, Davide Drigo, Carlo Nagliati, Andrea Muratore, Riccardo Danna, Alessandra Murgese, Michele Crespi, Claudio Guerci, Alice Frontali, Luca Ferrari, Francesco Favi, Erika Picariello, Alessia Rampini, Fabrizio D'Acapito, Giorgio Ercolani, Leonardo Solaini, Francesco Palmieri, Matteo Calì, Francesco Ferrara, Irnerio Angelo Muttillo, Edoardo Maria Muttillo, Biagio Picardi, Raffaele Galleano, Ali Badran, Omar Ghazouani, Maurizio Cervellera, Gaetano Campanella, Gennaro Papa, Annamaria Di Bella, Gennaro Perrone, Gabriele Luciano Petracca, Concetta Prioriello, Mario Giuffrida, Federico Cozzani, Matteo Rossini, Marco Inama, Giovanni Butturini, Gianluigi Moretto, Luca Morelli, Giulio Candio, Simone Guadagni, Enrico Cicuttin, Camilla Cremonini, Dario Tartaglia, Valerio Genovese, Nicola Cillara, Alessandro Cannavera, Antonello Deserra, Arcangelo Picciariello, Vincenzo Papagni, Leonardo Vincenti, Giulia Bagaglini, Giuseppe Sica, Pierfrancesco Lapolla, Gioia Brachini, Dario Bono, Antonella Nicotera, Marcello Zago, Fabrizio Sammartano, Laura Benuzzi, Marco Stella, Stefano Rossi, Alessandra Cerioli, Caterina Puccioni, Stefano Olmi, Carolina Rubicondo, Matteo Uccelli, Anna Guida, Pasquale Lepiane, Diego Sasia, Giorgio Giraudo, Sara Salomone, Elena Belloni, Alessandra Cossa, Francesco Lancellotti, Roberto Caronna, Piero Chirletti, Paolina Saullo, Raffaele Troiano, Felice Mucilli, Mirko Barone, Massimo Ippoliti, Michele Grande, Bruno Sensi, Leandro Siragusa, Andrea Santini, Isidoro Di Carlo, Massimiliano Veroux, Rossella Gioco, Gastone Veroux, Giuseppe Currò, Michele Ammendola, Iman Komaei, Giuseppe Navarra, Valeria Tonini, Lodovico Sartarelli, Marco Ceresoli, Stefano Perrone, Linda Roccamatisi, Paolo Millo, Riccardo Brachet Contul, Elisa Ponte, Matteo Zuin, Giuseppe Portale, Alice Sabrina Tonello, Geri Fratini, Matteo Bianchini, Bruno Perotti, Emanuele Doria, Elia Giuseppe Lunghi, Diego Visconti, Khayry Al-Shami, Sajeda Awadi, Mohammad Musallam Khalil Buwaitel, Mo'taz Fawzat Naief Naffa', Ahmad Samhouri, Hatem Sawalha, Mohd Firdaus Che Ani, Ida Nadiah Ahmed Fathil, Jih Huei, Jose-Luis Beristain-Hernandez, Alejandro Garcia-Meza, Rafael Sepulveda-Rdriguez, Edgard Efren Lozada Hernández, Camilo Levi Acuña Pinzón, Jefferson Nieves Condoy, Francisco C Becerra García, Mohammad Sadik, Bushra Kadir, Jalpa Devi, Nandlal Seerani, Zainab, Mohammad Sohail-Asghar, Ameer Afzal, Ali Akbar, Helmut Segovia Lohse, Herald Segovia Lohse, Zamiara Solange Leon Cabrera, Gaby Susana Yamamoto Seto, José Ríos Chiuyari, Jorge Ordemar, Martha Rodríguez, Abigail Cheska C Orantia-Carlos, Margie Antionette Quitoy, Andrzej Kwiatkowski, Maciej Mawlichanów, Mónica Rocha, Carlos Soares, Alexandru Rares Stoian, Andreea Diana Draghici, Valentin Titus Grigorean, Raluca Bievel Radulescu, Radu Virgil Costea, Eugenia Claudia Zarnescu, Mikhail Kurtenkov, George Gendrikson, Volovich Alla-Angelina, Tsurbanova Arina, Ayrat Kaldarov, Mahir Gachabayov, Abakar Abdullaev, Milica Milentijevic, Milovan Karamarkovic, Arpád Panyko, Jozef Radonak, Marek Soltes, Laura Álvarez Morán, Haydée Calvo García, Pilar Suárez Vega, Sergio Estevez, Fabio Ausania, Jordi Farguell, Carolina González-Abós, Santiago Sánchez-Cabús, Belén Martín, Víctor Molina, Luis Oms, Lucas Ilzarbe, Eva Pont Feijóo, Elena Sofia Perra, Noel Rojas-Bonet, Rafael Penalba-Palmí, Susana Pérez-Bru, Jaume Tur-Martínez, Andrea Álvarez-Torrado, Marta Domingo-Gonzalez, Javier Tejedor-Tejada, Yaiza García Del Alamo, Fernando Mendoza-Moreno, Francisca García-Moreno-Nisa, Belén Matías-García, Manuel Durán, Rafael Calleja-Lozano, José Manuel Perez de Villar, Luis Sánchez-Guillén, Iban Caravaca, Daniel Triguero-Cánovas, Antonio Carlos Maya Aparicio, Blas Durán Meléndez, Andrea Masiá Palacios, Aitor Landaluce-Olavarria, Mario De Francisco, Begoña Estraviz-Mateos, Felipe Alconchel, Tatiana Nicolás-López, Pablo Ramírez, Virginia Duran Muñoz-Cruzado, Felipe Parej Ciuró, Eduardo Perea Del Pozo, Sergio Olivares Pizarro, Vicente Herrera Cabrera, Jose Muros Bayo, Hytham K S Hamid, Raffaello Roesel, Alessandra Cristaudi, Kinan Abbas, Iyad Ali, Ahmed Tlili, Hüseyin Bayhan, Mehmet Akif Türkoğlu, Mustafa Yener Uzunoglu, Ibrahim Fethi Azamat, Nail Omarov, Derya Salim Uymaz, Fatih Altintoprak, Emrah Akin, Necattin First, Koray Das, Nazmi Ozer, Ahmet Seker, Yasin Kara, Mehmet Abdussamet Bozkurt, Ali Kocataş, Semra Demirli Atici, Murat Akalin, Bulent Calik, Elif Colak, Yuksel Altinel, Serhat Meric, Yunus Emre Aktimur, Victoria Hudson, Jean-Luc Duval, Mansoor Khan, Ahmed Saad, Mandeep Kaur, Alison Bradley, Katherine Fox, Ivan Tomasi, Daniel Beasley, Alekhya Kotta Prasanti, Pinky Kotecha, Husam Ebied, Michaela Paul, Hemant Sheth, Ioannis Gerogiannis, Mohannad Gaber, Zara Sheikh, Shatadru Seth, Maria Kunitsyna, Cosimo Alex Leo, Vittoria Bellato, Noman Zafar, Amr Elserafy, Giles Bond-Smith, Giovanni Tebala, Pawan Mathur, Izza Abid, Nnaemeka Chidumije, Pardip Sandhar, Syed Osama Zohaib Ullah, Tamara Lezama, Muhammad Hassan Anwaar, Conor Magee, Salma Ahmed, Brooke Davies, Jeyakumar Apollos, Kieran McCormack, Hasham Choudhary, Triantafyllos Doulias, Tamsin Morrison, Anna Palepa, Fernando Bonilla Cal, Lianet Sánchez, Fabiana Domínguez, Ibrahim Al-Raimi, Haneen Alshargabi, Abdullah Meead, Serge Chooklin, Serhii Chuklin, Andriy Bilyak, Institut Català de la Salut, [Podda M] Emergency Surgery Unit, Department of Surgical Science, Policlinico Universitario 'D. Casula', Azienda Ospedaliero-Universitaria di Cagliari, University of Cagliari, Cagliari, Italy. [Pellino G] Department of Advanced Medical and Surgical Sciences, Università degli Studi della Campania 'Luigi Vanvitelli', Naples, Italy. Unitat de Cirurgia de Còlon i Recte, Vall d’Hebron Hospital Universitari, Barcelona, Spain. [Di Saverio S] Department of Surgery, 'Madonna del Soccorso' Hospital, San Benedetto del Tronto, Italy. [Coccolini F] General, Emergency and Trauma Surgery Unit, Pisa University Hospital, Pisa, Italy. [Pacella D] Department of Public Health, University of Naples Federico II, Naples, Italy. [Cioffi SPB] Trauma and Acute Care Surgery Unit, 'Niguarda Ca Granda' Hospital, Milan, Italy, Vall d'Hebron Barcelona Hospital Campus, Podda, Mauro, Pellino, Gianluca, Di Saverio, Salomone, Coccolini, Federico, Pacella, Daniela, Cioffi, Stefano Piero Bernardo, Virdis, Francesco, Balla, Andrea, Ielpo, Benedetto, Pata, Francesco, Poillucci, Gaetano, Ortenzi, Monica, Damaskos, Dimitrio, De Simone, Belinda, Sartelli, Massimo, Leppaniemi, Ari, Jayant, Kumar, Catena, Fausto, Giuliani, Antonio, Di Martino, Marcello, Pisanu, Adolfo, Chiara Gerardi, Stavros Gourgiotis, Cristiana Riboni, Alessio Giordano, Luca Ferrario, Vanni Agnoletti, Yoram Kruger, Damian Mole, Ferdinando Agresta, Mikel Prieto Calvo, Michael Wilson, Fiammetta Soggiu, Alaa Hamdan, Carlos Augusto Gomes, Gustavo Fraga, Argyrios Ioannidis, Zaza Demetrashvili, Saaz Sahani, Lovenish Bains, Almu'atasim Khamees, Hazim Ababneh, Osama Aljaiuossi, Samuel Pimentel, Ikhwan Sani Mohamad, Ahmad Ramzi Yusoff, Narcis Octavian Zarnescu, Valentin Calu, Andrey Litvin, Dusan Lesko, Ahmed Elmehrath, Mohamedraed Elshami, Martin de Santibañes, Justin Gundara, Kamel Alawadhi, Rashid Lui, Alexander Julianov, Sergio Ralon, Ibrahim-Umar Garzali, Gustavo M Machain, Ibabe Villalabeitia, Darwin Artidoro Quispe-Cruz, Abigail Cheska C Orantia, Maciej Walędziak, Tiago Correia de Sá, Syed Muhammad Ali, Bojan Kovacevic, Colin Noel, Haidar M Abdalah, Ali Kchaou, Arda Isik, Luca Ansaloni, Walter Biffl, Mario Guerrieri, Alberto Sartori, Manuel Abradelo, Giuseppe Nigri, Nicola Di Lorenzo, Andrea Mingoli, Massimo Chiarugi, Juliana Di Menno Stavron, Oscar Mazza, José Ignacio Valenzuela, Diana Alejandra Pantoja Pachajoa, Fernando Andrés Alvarez, Julian Ezequiel Liaño, Joan Tefay, Abdulrahman Alshaikh, Layla Hasan, Felipe Couto Gomes, Thiago R A Calderan, Elcio S Hirano, Dragomir Dardanov, Alexander Julianov, Azize Saroglu, Boyko Atanasov, Nikolay Belev, Nikola Kovachev, Shannon Melissa Chan, Hon-Ting Lok, Diego Salcedo, Diana Robayo, María Alejandra Triviño, Jan Manak, Saaz Sahani, Jorann de Araujo, Ananya Sethi, Ahmed Awad, Merihan Elbadawy, Ahmed Farid, Asmaa Hanafy, Ahmed Nafea, Ghozy Sherief, Abbas Salah Alzhraa, Wafaa Abdelsalam, Sameh Emile, Ahmed Elfallal, Hossam Elfeki, Hosam Elghadban, Ashraf Shoma, Mohamed Shetiwy, Mohamed Elbahnasawy, Salem Mohamed, Emad Fawzi Hamed, Usama Ahmed Khalil, Elie Chouillard, Andrew Gumbs, Andrea Police, Andrea Mabilia, Kakhi Khutsishvili, Anano Tvaladze, Orestis Ioannidis, Elissavet Anestiadou, Lydia Loutzidou, Konstantinis Konstantinidis, Sofia Konstantinidou, Dimitrios Manatakis, Vasileios Acheimastos, Nikolaos Tasis, Nikolaos Michalopoulos, Panagiotis Kokoropoulos, Maria Papadoliopoulou, Maria Sotiropoulou, Stylianos Kapiris, Panagiotis Metaxas, Ioannis Tsouknidas, Despoina Kefili, George Petrakis, Eirini Synekidou, Konstantinos Dakis, Eirini Alexandridou, Aristeidis Papadopoulos, Christos Chouliaras, Odysseas Mouzakis, Francesk Mulita, Ioannis Maroulis, Michail Vailas, Tania Triantafyllou, Dimitrios Theodorou, Eftychios Lostoridis, Eleni-Aikaterini Nagorni, Paraskevi Tourountzi, Efstratia Baili, Alexandros Charalabopoulos, Theodore Liakakos, Dimitrios Schizas, Alexandros Kozadinos, Athanasios Syllaios, Nikolaos Machairas, Stylianos Kykalos, Paraskevas Stamopoulos, Spiros Delis, Christos Farazi-Chongouki, Evangelos Kalaitzakis, Miltiadis Giannarakis, Konstantinos Lasithiotakis, Giorgia Petra, Evangelos Kalaitzakis, Amit Gupta, Noushif Medappil, Vijayanand Muthukrishnan, Jubin Kamar, Pawan Lal, Rajendra Agarwal, Matteo Magnoli, Paolo Aonzo, Alberto Serventi, Pierpaolo Di Lascio, Margherita Pinto, Carlo Bergamini, Andrea Bottari, Laura Fortuna, Jacopo Martellucci, Atea Cicako, Claudio Miglietta, Mario Morino, Daniele Delogu, Andrea Picchetto, Marco Assenza, Giancarlo D'Ambrosio, Giulio Argenio, Mariano Fortunato Armellino, Giovanna Ioia, Savino Occhionorelli, Dario Andreotti, Lacavalla Domenico, Davide Luppi, Massimiliano Casadei, Luca Di Donato, Farshad Manoochehri, Tiziana Rita Lucia Marchese, William Sergi, Roberto Manca, Raimondo Murgia, Enrico Piras, Lorenzo Conti, Simone Gianazza, Andrea Rizzi, Edoardo Segalini, Marco Monti, Elena Iiritano, Nicolò Maria Mariani, Enrico De Nicola, Giovanna Scifo, Giusto Pignata, Jacopo Andreuccetti, Francesco Fleres, Guglielmo Clarizia, Alessandro Spolini, Alan Biloslavo, Paola Germani, Manuela Mastronardi, Selene Bogoni, Silvia Palmisano, Nicolo' De Manzini, Marco Vito Marino, Gennaro Martines, Giuseppe Trigiante, Elpiniki Lagouvardou, Gabriele Anania, Cristina Bombardini, Dario Oppici, Tiziana Pilia, Valentina Murzi, Emanuela Gessa, Umberto Bracale, Maria Michela Di Nuzzo, Roberto Peltrini, Francesco Salvetti, Jacopo Viganò, Gabriele Sganga, Valentina Bianchi, Pietro Fransvea, Tommaso Fontana, Giuliano Sarro, Vincenza Paola Dinuzzi, Luca Scaravilli, Mario Virgilio Papa, Elio Jovine, Giulia Ciabatti, Laura Mastrangelo, Matteo Rottoli, Claudio Ricci, Iris Shari Russo, Alberto Aiolfi, Davide Bona, Francesca Lombardo, Pasquale Cianci, Mariagrazia Sederino, Roberto Bini, Osvaldo Chiara, Stefano Cioffi, Stefano Cantafio, Guido Coretti, Edelweiss Licitra, Grazia Savino, Sergio Grimaldi, Raffaele Porfidia, Elisabetta Moggia, Mauro Garino, Chiara Marafante, Antonio Pesce, Nicolò Fabbri, Carlo Vittorio Feo, Ester Marra, Marina Troian, Davide Drigo, Carlo Nagliati, Andrea Muratore, Riccardo Danna, Alessandra Murgese, Michele Crespi, Claudio Guerci, Alice Frontali, Luca Ferrari, Claudio Guerci, Francesco Favi, Erika Picariello, Alessia Rampini, Fabrizio D'Acapito, Giorgio Ercolani, Leonardo Solaini, Francesco Palmieri, Matteo Calì, Francesco Ferrara, Irnerio Angelo Muttillo, Edoardo Maria Muttillo, Biagio Picardi, Raffaele Galleano, Ali Badran, Omar Ghazouani, Maurizio Cervellera, Gaetano Campanella, Gennaro Papa, Annamaria Di Bella, Gennaro Perrone, Gabriele Luciano Petracca, Concetta Prioriello, Mario Giuffrida, Federico Cozzani, Matteo Rossini, Marco Inama, Giovanni Butturini, Gianluigi Moretto, Luca Morelli, Giulio Candio, Simone Guadagni, Enrico Cicuttin, Camilla Cremonini, Dario Tartaglia, Valerio Genovese, Nicola Cillara, Alessandro Cannavera, Antonello Deserra, Arcangelo Picciariello, Vincenzo Papagni, Leonardo Vincenti, Giulia Bagaglini, Giuseppe Sica, Pierfrancesco Lapolla, Gioia Brachini, Dario Bono, Antonella Nicotera, Marcello Zago, Fabrizio Sammartano, Laura Benuzzi, Marco Stella, Stefano Rossi, Alessandra Cerioli, Caterina Puccioni, Stefano Olmi, Carolina Rubicondo, Matteo Uccelli, Anna Guida, Pasquale Lepiane, Diego Sasia, Giorgio Giraudo, Sara Salomone, Elena Belloni, Alessandra Cossa, Francesco Lancellotti, Roberto Caronna, Piero Chirletti, Paolina Saullo, Raffaele Troiano, Felice Mucilli, Mirko Barone, Massimo Ippoliti, Michele Grande, Bruno Sensi, Leandro Siragusa, Andrea Santini, Isidoro Di Carlo, Massimiliano Veroux, Rossella Gioco, Gastone Veroux, Giuseppe Currò, Michele Ammendola, Iman Komaei, Giuseppe Navarra, Valeria Tonini, Lodovico Sartarelli, Marco Ceresoli, Stefano Perrone, Linda Roccamatisi, Paolo Millo, Riccardo Brachet Contul, Elisa Ponte, Matteo Zuin, Giuseppe Portale, Alice Sabrina Tonello, Geri Fratini, Matteo Bianchini, Bruno Perotti, Emanuele Doria, Elia Giuseppe Lunghi, Diego Visconti, Khayry Al-Shami, Sajeda Awadi, Mohammad Musallam Khalil Buwaitel, Mo'taz Fawzat Naief Naffa', Ahmad Samhouri, Hatem Sawalha, Mohd Firdaus Che Ani, Ida Nadiah Ahmed Fathil, Jih Huei, Ikhwan Sani Mohamad, Jose-Luis Beristain-Hernandez, Alejandro Garcia-Meza, Rafael Sepulveda-Rdriguez, Edgard Efren Lozada Hernández, Camilo Levi Acuña Pinzón, Jefferson Nieves Condoy, Francisco C Becerra García, Mohammad Sadik, Bushra Kadir, Jalpa Devi, Nandlal Seerani, Zainab, Mohammad Sohail-Asghar, Ameer Afzal, Ali Akbar, Helmut Segovia Lohse, Herald Segovia Lohse, Zamiara Solange Leon Cabrera, Gaby Susana Yamamoto Seto, José Ríos Chiuyari, Jorge Ordemar, Martha Rodríguez, Abigail Cheska C Orantia-Carlos, Margie Antionette Quitoy, Andrzej Kwiatkowski, Maciej Mawlichanów, Mónica Rocha, Carlos Soares, Alexandru Rares Stoian, Andreea Diana Draghici, Valentin Titus Grigorean, Raluca Bievel Radulescu, Narcis Octavian Zarnescu, Radu Virgil Costea, Eugenia Claudia Zarnescu, Mikhail Kurtenkov, George Gendrikson, Volovich Alla-Angelina, Tsurbanova Arina, Ayrat Kaldarov, Ayrat Kaldarov, Mahir Gachabayov, Abakar Abdullaev, Milica Milentijevic, Milovan Karamarkovic, Arpád Panyko, Jozef Radonak, Marek Soltes, Laura Álvarez Morán, Haydée Calvo García, Pilar Suárez Vega, Sergio Estevez, Fabio Ausania, Jordi Farguell, Carolina González-Abós, Santiago Sánchez-Cabús, Belén Martín, Víctor Molina, Luis Oms, Lucas Ilzarbe, Eva Pont Feijóo, Elena Sofia Perra, Noel Rojas-Bonet, Rafael Penalba-Palmí, Susana Pérez-Bru, Jaume Tur-Martínez, Andrea Álvarez-Torrado, Marta Domingo-Gonzalez, Javier Tejedor-Tejada, Yaiza García Del Alamo, Fernando Mendoza-Moreno, Francisca García-Moreno-Nisa, Belén Matías-García, Manuel Durán, Rafael Calleja-Lozano, José Manuel Perez de Villar, Luis Sánchez-Guillén, Iban Caravaca, Daniel Triguero-Cánovas, Antonio Carlos Maya Aparicio, Blas Durán Meléndez, Andrea Masiá Palacios, Aitor Landaluce-Olavarria, Mario De Francisco, Begoña Estraviz-Mateos, Felipe Alconchel, Tatiana Nicolás-López, Pablo Ramírez, Virginia Duran Muñoz-Cruzado, Felipe Parej Ciuró, Eduardo Perea Del Pozo, Sergio Olivares Pizarro, Vicente Herrera Cabrera, Jose Muros Bayo, Hytham K S Hamid, Raffaello Roesel, Alessandra Cristaudi, Kinan Abbas, Iyad Ali, Ahmed Tlili, Hüseyin Bayhan, Mehmet Akif Türkoğlu, Mustafa Yener Uzunoglu, Ibrahim Fethi Azamat, Nail Omarov, Derya Salim Uymaz, Fatih Altintoprak, Emrah Akin, Necattin First, Koray Das, Nazmi Ozer, Ahmet Seker, Yasin Kara, Mehmet Abdussamet Bozkurt, Ali Kocataş, Semra Demirli Atici, Murat Akalin, Bulent Calik, Elif Colak, Yuksel Altinel, Serhat Meric, Yunus Emre Aktimur, Victoria Hudson, Jean-Luc Duval, Mansoor Khan, Ahmed Saad, Mandeep Kaur, Alison Bradley, Katherine Fox, Ivan Tomasi, Daniel Beasley, Alekhya Kotta Prasanti, Pinky Kotecha, Husam Ebied, Michaela Paul, Hemant Sheth, Ioannis Gerogiannis, Mohannad Gaber, Zara Sheikh, Shatadru Seth, Maria Kunitsyna, Cosimo Alex Leo, Vittoria Bellato, Noman Zafar, Amr Elserafy, Giles Bond-Smith, Giovanni Tebala, Pawan Mathur, Izza Abid, Nnaemeka Chidumije, Pardip Sandhar, Syed Osama Zohaib Ullah, Tamara Lezama, Muhammad Hassan Anwaar, Conor Magee, Salma Ahmed, Brooke Davies, Jeyakumar Apollos, Kieran McCormack, Hasham Choudhary, Triantafyllos Doulias, Tamsin Morrison, Anna Palepa, Fernando Bonilla Cal, Lianet Sánchez, Fabiana Domínguez, Ibrahim Al-Raimi, Haneen Alshargabi, Abdullah Meead, Serge Chooklin, Serhii Chuklin, Andriy Bilyak, HUS Abdominal Center, II kirurgian klinikka, Podda, M, Pellino, G, Di Saverio, S, Coccolini, F, Pacella, D, Cioffi, S, Virdis, F, Balla, A, Ielpo, B, Pata, F, Poillucci, G, Ortenzi, M, Damaskos, D, De Simone, B, Sartelli, M, Leppaniemi, A, Jayant, K, Catena, F, Giuliani, A, Di Martino, M, Pisanu, A, Gerardi, C, Gourgiotis, S, Riboni, C, Giordano, A, Ferrario, L, Agnoletti, V, Kruger, Y, Mole, D, Agresta, F, Prieto Calvo, M, Wilson, M, Soggiu, F, Hamdan, A, Gomes, C, Fraga, G, Ioannidis, A, Demetrashvili, Z, Sahani, S, Bains, L, Khamees, A, Ababneh, H, Aljaiuossi, O, Pimentel, S, Mohamad, I, Yusoff, A, Zarnescu, N, Calu, V, Litvin, A, Lesko, D, Elmehrath, A, Elshami, M, de Santibanes, M, Gundara, J, Alawadhi, K, Lui, R, Julianov, A, Ralon, S, Garzali, I, Machain, G, Villalabeitia, I, Quispe-Cruz, D, Orantia, A, Waledziak, M, de Sa, T, Ali, S, Kovacevic, B, Noel, C, Abdalah, H, Kchaou, A, Isik, A, Ansaloni, L, Biffl, W, Guerrieri, M, Sartori, A, Abradelo, M, Nigri, G, Di Lorenzo, N, Mingoli, A, Chiarugi, M, Di Menno Stavron, J, Mazza, O, Valenzuela, J, Pachajoa, D, Alvarez, F, Liano, J, Tefay, J, Alshaikh, A, Hasan, L, Couto Gomes, F, Calderan, T, Hirano, E, Dardanov, D, Saroglu, A, Atanasov, B, Belev, N, Kovachev, N, Chan, S, Lok, H, Salcedo, D, Robayo, D, Trivino, M, Manak, J, de Araujo, J, Sethi, A, Awad, A, Elbadawy, M, Farid, A, Hanafy, A, Nafea, A, Sherief, G, Salah Alzhraa, A, Abdelsalam, W, Emile, S, Elfallal, A, Elfeki, H, Elghadban, H, Shoma, A, Shetiwy, M, Elbahnasawy, M, Mohamed, S, Hamed, E, Khalil, U, Chouillard, E, Gumbs, A, Police, A, Mabilia, A, Khutsishvili, K, Tvaladze, A, Ioannidis, O, Anestiadou, E, Loutzidou, L, Konstantinidis, K, Konstantinidou, S, Manatakis, D, Acheimastos, V, Tasis, N, Michalopoulos, N, Kokoropoulos, P, Papadoliopoulou, M, Sotiropoulou, M, Kapiris, S, Metaxas, P, Tsouknidas, I, Kefili, D, Petrakis, G, Synekidou, E, Dakis, K, Alexandridou, E, Papadopoulos, A, Chouliaras, C, Mouzakis, O, Mulita, F, Maroulis, I, Vailas, M, Triantafyllou, T, Theodorou, D, Lostoridis, E, Nagorni, E, Tourountzi, P, Baili, E, Charalabopoulos, A, Liakakos, T, Schizas, D, Kozadinos, A, Syllaios, A, Machairas, N, Kykalos, S, Stamopoulos, P, Delis, S, Farazi-Chongouki, C, Kalaitzakis, E, Giannarakis, M, Lasithiotakis, K, Petra, G, Gupta, A, Medappil, N, Muthukrishnan, V, Kamar, J, Lal, P, Agarwal, R, Magnoli, M, Aonzo, P, Serventi, A, Di Lascio, P, Pinto, M, Bergamini, C, Bottari, A, Fortuna, L, Martellucci, J, Cicako, A, Miglietta, C, Morino, M, Delogu, D, Picchetto, A, Assenza, M, D'Ambrosio, G, Argenio, G, Armellino, M, Ioia, G, Occhionorelli, S, Andreotti, D, Domenico, L, Luppi, D, Casadei, M, Di Donato, L, Manoochehri, F, Marchese, T, Sergi, W, Manca, R, Murgia, R, Piras, E, Conti, L, Gianazza, S, Rizzi, A, Segalini, E, Monti, M, Iiritano, E, Mariani, N, De Nicola, E, Scifo, G, Pignata, G, Andreuccetti, J, Fleres, F, Clarizia, G, Spolini, A, Biloslavo, A, Germani, P, Mastronardi, M, Bogoni, S, Palmisano, S, De Manzini, N, Marino, M, Martines, G, Trigiante, G, Lagouvardou, E, Anania, G, Bombardini, C, Oppici, D, Pilia, T, Murzi, V, Gessa, E, Bracale, U, Di Nuzzo, M, Peltrini, R, Salvetti, F, Vigano, J, Sganga, G, Bianchi, V, Fransvea, P, Fontana, T, Sarro, G, Dinuzzi, V, Scaravilli, L, Papa, M, Jovine, E, Ciabatti, G, Mastrangelo, L, Rottoli, M, Ricci, C, Russo, I, Aiolfi, A, Bona, D, Lombardo, F, Cianci, P, Sederino, M, Bini, R, Chiara, O, Cantafio, S, Coretti, G, Licitra, E, Savino, G, Grimaldi, S, Porfidia, R, Moggia, E, Garino, M, Marafante, C, Pesce, A, Fabbri, N, Feo, C, Marra, E, Troian, M, Drigo, D, Nagliati, C, Muratore, A, Danna, R, Murgese, A, Crespi, M, Guerci, C, Frontali, A, Ferrari, L, Favi, F, Picariello, E, Rampini, A, D'Acapito, F, Ercolani, G, Solaini, L, Palmieri, F, Cali, M, Ferrara, F, Muttillo, I, Muttillo, E, Picardi, B, Galleano, R, Badran, A, Ghazouani, O, Cervellera, M, Campanella, G, Papa, G, Di Bella, A, Perrone, G, Petracca, G, Prioriello, C, Giuffrida, M, Cozzani, F, Rossini, M, Inama, M, Butturini, G, Moretto, G, Morelli, L, Candio, G, Guadagni, S, Cicuttin, E, Cremonini, C, Tartaglia, D, Genovese, V, Cillara, N, Cannavera, A, Deserra, A, Picciariello, A, Papagni, V, Vincenti, L, Bagaglini, G, Sica, G, Lapolla, P, Brachini, G, Bono, D, Nicotera, A, Zago, M, Sammartano, F, Benuzzi, L, Stella, M, Rossi, S, Cerioli, A, Puccioni, C, Olmi, S, Rubicondo, C, Uccelli, M, Guida, A, Lepiane, P, Sasia, D, Giraudo, G, Salomone, S, Belloni, E, Cossa, A, Lancellotti, F, Caronna, R, Chirletti, P, Saullo, P, Troiano, R, Mucilli, F, Barone, M, Ippoliti, M, Grande, M, Sensi, B, Siragusa, L, Santini, A, Di Carlo, I, Veroux, M, Gioco, R, Veroux, G, Curro, G, Ammendola, M, Komaei, I, Navarra, G, Tonini, V, Sartarelli, L, Ceresoli, M, Perrone, S, Roccamatisi, L, Millo, P, Brachet Contul, R, Ponte, E, Zuin, M, Portale, G, Tonello, A, Fratini, G, Bianchini, M, Perotti, B, Doria, E, Lunghi, E, Visconti, D, Al-Shami, K, Awadi, S, Buwaitel, M, Naffa', M, Samhouri, A, Sawalha, H, Ani, M, Fathil, I, Huei, J, Beristain-Hernandez, J, Garcia-Meza, A, Sepulveda-Rdriguez, R, Hernandez, E, Pinzon, C, Condoy, J, Garcia, F, Sadik, M, Kadir, B, Devi, J, Seerani, N, Zainab, Sohail-Asghar, M, Afzal, A, Akbar, A, Lohse, H, Cabrera, Z, Seto, G, Chiuyari, J, Ordemar, J, Rodriguez, M, Orantia-Carlos, A, Quitoy, M, Kwiatkowski, A, Mawlichanow, M, Rocha, M, Soares, C, Stoian, A, Draghici, A, Grigorean, V, Radulescu, R, Costea, R, Zarnescu, E, Kurtenkov, M, Gendrikson, G, Alla-Angelina, V, Arina, T, Kaldarov, A, Gachabayov, M, Abdullaev, A, Milentijevic, M, Karamarkovic, M, Panyko, A, Radonak, J, Soltes, M, Moran, L, Garcia, H, Vega, P, Estevez, S, Ausania, F, Farguell, J, Gonzalez-Abos, C, Sanchez-Cabus, S, Martin, B, Molina, V, Oms, L, Ilzarbe, L, Feijoo, E, Perra, E, Rojas-Bonet, N, Penalba-Palmi, R, Perez-Bru, S, Tur-Martinez, J, Alvarez-Torrado, A, Domingo-Gonzalez, M, Tejedor-Tejada, J, del Alamo, Y, Mendoza-Moreno, F, Garcia-Moreno-Nisa, F, Matias-Garcia, B, Duran, M, Calleja-Lozano, R, de Villar, J, Sanchez-Guillen, L, Caravaca, I, Triguero-Canovas, D, Aparicio, A, Melendez, B, Palacios, A, Landaluce-Olavarria, A, De Francisco, M, Estraviz-Mateos, B, Alconchel, F, Nicolas-Lopez, T, Ramirez, P, Munoz-Cruzado, V, Ciuro, F, del Pozo, E, Pizarro, S, Cabrera, V, Bayo, J, Hamid, H, Roesel, R, Cristaudi, A, Abbas, K, Ali, I, Tlili, A, Bayhan, H, Turkoglu, M, Uzunoglu, M, Azamat, I, Omarov, N, Uymaz, D, Altintoprak, F, Akin, E, First, N, Das, K, Ozer, N, Seker, A, Kara, Y, Bozkurt, M, Kocatas, A, Atici, S, Akalin, M, Calik, B, Colak, E, Altinel, Y, Meric, S, Aktimur, Y, Hudson, V, Duval, J, Khan, M, Saad, A, Kaur, M, Bradley, A, Fox, K, Tomasi, I, Beasley, D, Prasanti, A, Kotecha, P, Ebied, H, Paul, M, Sheth, H, Gerogiannis, I, Gaber, M, Sheikh, Z, Seth, S, Kunitsyna, M, Leo, C, Bellato, V, Zafar, N, Elserafy, A, Bond-smith, G, Tebala, G, Mathur, P, Abid, I, Chidumije, N, Sandhar, P, Ullah, S, Lezama, T, Anwaar, M, Magee, C, Ahmed, S, Davies, B, Apollos, J, Mccormack, K, Choudhary, H, Doulias, T, Morrison, T, Palepa, A, Cal, F, Sanchez, L, Dominguez, F, Al-Raimi, I, Alshargabi, H, Meead, A, Chooklin, S, Chuklin, S, Bilyak, A, MANCTRA-1 Collaborative, Group, Palmisano, Silvia, and de Manzini, Nicolo'
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Infected pancreatic necrosi ,Digestive System Diseases::Pancreatic Diseases::Pancreatitis::Pancreatitis, Acute Necrotizing [DISEASES] ,Infected pancreatic necrosis ,Pàncrees - Infecció ,3126 Surgery, anesthesiology, intensive care, radiology ,enfermedades del sistema digestivo::enfermedades pancreáticas::pancreatitis::pancreatitis aguda necrotizante [ENFERMEDADES] ,técnicas de investigación::métodos epidemiológicos::estadística como asunto::probabilidad::riesgo::factores de riesgo [TÉCNICAS Y EQUIPOS ANALÍTICOS, DIAGNÓSTICOS Y TERAPÉUTICOS] ,Acute pancreatitis ,infecciones bacterianas y micosis::infección::infecciones intraabdominales [ENFERMEDADES] ,Pancreatitis ,International study ,Organ failure ,Surgery ,Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Probability::Risk::Risk Factors [ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT] ,Mortality ,Acute pancreatiti ,Pàncrees - Necrosi ,Bacterial Infections and Mycoses::Infection::Intraabdominal Infections [DISEASES] - Abstract
The identification of high-risk patients in the early stages of infected pancreatic necrosis (IPN) is critical, because it could help the clinicians to adopt more effective management strategies. We conducted a post hoc analysis of the MANCTRA-1 international study to assess the association between clinical risk factors and mortality among adult patients with IPN. Univariable and multivariable logistic regression models were used to identify prognostic factors of mortality. We identified 247 consecutive patients with IPN hospitalised between January 2019 and December 2020. History of uncontrolled arterial hypertension (p = 0.032; 95% CI 1.135–15.882; aOR 4.245), qSOFA (p = 0.005; 95% CI 1.359–5.879; aOR 2.828), renal failure (p = 0.022; 95% CI 1.138–5.442; aOR 2.489), and haemodynamic failure (p = 0.018; 95% CI 1.184–5.978; aOR 2.661), were identified as independent predictors of mortality in IPN patients. Cholangitis (p = 0.003; 95% CI 1.598–9.930; aOR 3.983), abdominal compartment syndrome (p = 0.032; 95% CI 1.090–6.967; aOR 2.735), and gastrointestinal/intra-abdominal bleeding (p = 0.009; 95% CI 1.286–5.712; aOR 2.710) were independently associated with the risk of mortality. Upfront open surgical necrosectomy was strongly associated with the risk of mortality (p p = 0.018; 95% CI 0.138–0.834; aOR 0.339) and enteral nutrition (p = 0.003; 95% CI 0.143–0.716; aOR 0.320) were found as protective factors. Organ failure, acute cholangitis, and upfront open surgical necrosectomy were the most significant predictors of mortality. Our study confirmed that, even in a subgroup of particularly ill patients such as those with IPN, upfront open surgery should be avoided as much as possible. Study protocol registered in ClinicalTrials.Gov (I.D. Number NCT04747990). Graphical abstract
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- 2023
3. Antonio Rubial, Brian Connaughton, Manuel Ceballos y Roberto Blancarte, Historia mínima de la Iglesia católica en México
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Octavio Spindola Zago
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General Medicine - Published
- 2023
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4. USO DO AZEITE DE OLIVA (OLEA EUROPAEA L.) EM PREPARAÇÕES CULINÁRIAS QUENTES: ELABORAÇÃO DE MATERIAL INFORMATIVO PARA POPULARIZAÇÃO DO CONHECIMENTO CIENTÍFICO
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Lilia Zago, Paolla Chrystal Roriz Braga, and Isabelle Santana
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General Medicine - Abstract
O azeite de oliva é amplamente consumido devido às suas propriedades benéficas para a saúde e características sensoriais únicas. A composição química abundante em ácido graxo monoinsaturado, associada ao perfil de compostos fenólicos com importante efeito antioxidante, confere ao azeite de oliva alta estabilidade ao aquecimento. Embora existam muitas evidências sobre a estabilidade térmica do azeite, ainda existem muitas dúvidas, por parte da população, sobre o uso em técnicas culinárias que envolvam calor. O objetivo desse trabalho foi compilar evidências científicas a respeito da influência de técnicas culinárias sobre a estabilidade térmica do azeite de oliva, com vistas a elaborar material informativo, com linguagem adaptada à população em geral, sobre sua utilização na culinária, especialmente em preparações quentes. É de amplo conhecimento na literatura que o azeite de oliva é bastante resistente à cocção, no entanto, temperaturas elevadas, como as empregadas na fritura por imersão, podem levar a diminuição do teor de compostos fenólicos, a depender da quantidade e tipos de fenólicos presentes no azeite. Estudos no contexto da gastronomia molecular também relatam, além da estabilidade térmica, os benefícios da utilização do azeite de oliva na culinária devido às interações químicas entre os compostos do azeite e os compostos do alimento fazendo com que ambos (óleo e alimentos) se beneficiem dos efeitos protetivos desses compostos. Considerando que ainda é muito comum o uso do azeite de oliva apenas para temperar saladas e finalizar pratos, o infográfico elaborado no presente trabalho pode contribuir para apresentar o conteúdo científico sobre o uso do azeite em preparações culinárias quentes de forma simplificada e de fácil compreensão.
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- 2023
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5. NOTIFICAÇÕES DE TUBERCULOSE NO PERÍODO PRÉ-PANDÊMICO E PANDÊMICO DA COVID-19 NO ESTADO DO PARANÁ
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Thalise Salas Borges, Alexandre Leseur Dos Santos, Silvia Cristina Osaki, and Cláudia Helena Ferreira Zago Dias
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General Medicine - Abstract
Introdução: A tuberculose (TB) é considerada uma doença bem desafiadora para o sistema de saúde no Brasil, devido ao número elevado de casos nas últimas décadas. Contudo, com a pandemia da COVID-19, foi observada uma redução significativa de casos de TB. Objetivo: O objetivo desse trabalho foi avaliar o comportamento da TB nas macrorregionais de saúde do estado do Paraná, bem como nas populações vulneráveis nos anos de 2011 a 2021, e sua associação com a ocorrências de casos de COVID-19 a partir de 2020. Metodologia: Trata-se de um estudo ecológico, com dados secundários de TB do Sistema de Informação de Agravos de Notificação (SINAN) e de COVID-19 no banco de dados público oficial da Secretaria de Estado da Saúde do Paraná (SESA) para o coronavírus. Principais resultados: Foi observada diferenças significativas de ocorrência de casos de TB entre as macrorregionais relacionadas à faixa etária da população e entre os períodos pré-pandêmico e pandêmico no Paraná. Os dados obtidos apontam também para uma associação significativa de casos de TB em populações em situação de rua, privadas de liberdade e portadores do vírus da imunodeficiência humana (HIV) no estado ao longo dos anos observados. Conclusão: As notificações de TB no estado do Paraná foram afetadas pela pandemia da COVID-19.
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- 2023
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6. Die Rolle der Herkunftssprachen auf der Tertiärstufe am Beispiel der Hochschule für Wirtschaft Freiburg
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Elisabeth Reiser-Bello Zago and Annina Keller
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Während hierzulande in Schulsprachendebatten oft über Erstsprachen von Kindern diskutiert wird, ist nur wenig darüber bekannt, wie migrationsbedingt mehrsprachige Studierende ihre Herkunftssprachen erleben. Anhand einer Umfrage an der Hochschule für Wirtschaft Freiburg wurde diese Zielgruppe zur Rolle ihrer Herkunftssprachen im – offiziell dreisprachigen – Studienalltag befragt. Wünschen sie sich etwa, dass diese Sprachen in den Kursen berücksichtigt werden? Die Resultate zeigen, dass die Studierenden ihre Herkunftssprachen im privaten Umfeld wertschätzen. Die Mehrheit ist allerdings der Meinung, sie hätten im Studium und auch am Arbeitsplatz keinen grossen Platz.
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- 2023
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7. SANTA ANITA: THE CITY OF LOVE
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Cléia Viana Guimarães and Rosemara Staub de Barros Zago
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- 2023
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8. Relação entre dermatite atópica e alergias
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Ariane Sponchiado Assoni, Laura Corradi Pagliosa, Victória Sponchiado, Gabriela Comin, Martina Picolo Rossatto, and Poliana Zago Perondi
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General Medicine - Abstract
A Dermatite atópica faz parte da tríade atópica - dermatite atópica, asma e rinite alérgica - e é caracterizada por surtos eczematosos inflamatórios e pruriginosos. Esse quadro pode progredir para uma sensibilização às proteínas do leite de vaca, ovo ou amendoim e ainda para uma sensibilização aos aeroalérgenos. Assim, o presente estudo tem como objetivo analisar a relação entre a dermatite atópica e as alergias.
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- 2023
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9. A transcriptome analysis of basal and stimulated VWF release from endothelial cells derived from patients with type 1 VWD
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Robert Kloosterman, Matteo Zago-Schmitt, Julie Grabell, Lisa Thibeault, Patricia A. De Lima, Mackenzie Bowman, Kathrin Tyryshkin, Charles C. T. Hindmarch, Neil Renwick, and Paula James
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Hematology - Abstract
Type 1 von Willebrand disease (VWD) is associated with a reduction in qualitatively normal von Willebrand factor (VWF). Current diagnostic guidelines only take into consideration the contribution of basal VWF levels, despite a lack of correlation with bleeding severity. Defects in stimulated VWF release, which occurs after hemostatic challenge, may contribute to bleeding in type 1 VWD, but the pathogenic mechanisms are poorly defined. In this study, a layered multiomic approach including messenger RNA (mRNA) and microRNA (miRNA) sequencing was used to evaluate transcriptome-wide differences between type 1 VWD- and control-derived endothelial colony forming cells (ECFCs) during basal and stimulated VWF release. ECFCs from 8 patients with type 1 VWD and 4 other patients were included in this study as controls. VWF protein analysis revealed heterogenous responses to stimulation among type 1 VWD and control ECFCs. During basal VWF release, 64 mRNAs and 7 miRNAs were differentially regulated between type 1 VWD and control ECFCs, and 65 putatively pathogenic miRNA-mRNA interactions were identified. During stimulated VWF release, 190 mRNAs and 5 mRNAs were differentially regulated between type 1 VWD and control ECFCs, and 110 putatively pathogenic miRNA-mRNA interactions were identified. Five gene ontology terms including coagulation, regulation of cell shape, and regulation of cell signaling were also differentially regulated in type 1 VWD ECFCs during stimulated release. To our knowledge, we have shown for the first time that transcriptome-wide differences exist between type 1 VWD and control ECFCs. These differences may contribute to bleeding in type 1 VWD, and further investigation may reveal novel biomarkers and therapeutic targets.
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- 2023
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10. Novel avenues to control blood pressure: targeting the renal lymphatic system
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Andreia Zago Chignalia
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General Medicine - Abstract
Hypertension is associated with the activation of the immune and lymphatic systems as well as lymphangiogenesis. The changes in the lymphatic system are considered an adaptive response to mitigate the deleterious effects of immune and inflammatory cells on the cardiovascular system. In the article recently published in Clinical Science by Goodlett and collaborators, evidence is shown that inducing renal lymphangiogenesis after the establishment of hypertension in mice is an effective maneuver to reduce systemic arterial blood pressure. In this commentary, we will briefly review what is known about the relationship between the activation of the immune and lymphatic systems, and the resulting effects on systemic blood pressure, summarize the findings published by Goodlett and collaborators, and discuss the impact of their findings on the field.
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- 2023
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11. Reducing the environmental impact of surgery on a global scale: systematic review and co-prioritization with healthcare workers in 132 countries
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Global Health Research Unit on Global Surgery, National Institute for Health and Care Research, Adisa, Adewale, Bahrami-Hessari, Michael, Bhangu, Aneel, George, Christina, Ghosh, Dhruv, Glasbey, James, Haque, Parvez, Ingabire, J C Allen, Kamarajah, Sivesh Kathir, Kudrna, Laura, Ledda, Virginia, Li, Elizabeth, Lillywhite, Robert, Mittal, Rohin, Nepogodiev, Dmitri, Ntirenganya, Faustin, Picciochi, Maria, Simões, Joana Filipa Ferreira, Booth, L, Elliot, R, Kennerton, A S, Pettigrove, K L, Pinney, L, Richard, H, Tottman, R, Wheatstone, P, Wolfenden, John W D, Smith, A, Sayed, A Emad, Goswami, Aakansha Giri, Malik, Aamer, Mclean, Aaron Lawson, Hassan, Abbas, Nazimi, Abd Jabar, Aladna, Abdallah, Abdelgawad, Abdalrahman, Saed, Abdel, Abdelmageed, Abdelfatah, Ghannam, Abdelilah, Mahmoud, Abdelrahman, Alvi, Abdul, Ismail, Abdulaziz, Adesunkanmi, Abdulhafiz, Ebrahim, Abdulla, Al-Mallah, Abdullah, Alqallaf, Abdullah, Durrani, Abdullah, Gabr, Abdullah, Kirfi, Abdullahi Musa, Altaf, Abdulmalik, Almutairi, Abdulmjeed, Sabbagh, Abdulrahman J, Ajiya, Abdulrazak, Haddud, Abdurrahman, Alnsour, Abed Alfattah Mahmoud, Singh, Abhinav, Mittal, Abhishek, Semple, Abigail, Adeniran, Abiodun, Negussie, Abraham, Oladimeji, Abraham, Muhammad, Abubakar Bala, Yassin, Abubaker, Gungor, Abuzer, Tarsitano, Achille, Soibiharry, Adaiah, Dyas, Adam, Frankel, Adam, Peckham-Cooper, Adam, Truss, Adam, Issaka, Adamu, Ads, Adel Mohamed, Aderogba, Adeleke Akeem, Adeyeye, Ademola, Ademuyiwa, Adesoji, Sleem, Adham, Papa, Adrian, Cordova, Adriana, Appiah-Kubi, Adu, Meead, Adullah, Nacion, Aeris Jane D, Michael, Afieharo, Forneris, Agustin Albani, Duro, Agustin, Gonzalez, Agustin Rodriguez, Altouny, Ahmad, Ghazal, Ahmad, Khalifa, Ahmad, Ozair, Ahmad, Quzli, Ahmad, Haddad, Ahmad, Othman, Ahmad Faidzal, Yahaya, Ahmad Shuib, Elsherbiny, Ahmed, Nazer, Ahmed, Tarek, Ahmed, Abu-Zaid, Ahmed, Al-Nusairi, Ahmed, Azab, Ahmed, Elagili, Ahmed, Elkazaz, Ahmed, Kedwany, Ahmed, Nuhu, Ahmed Mohammed, Sakr, Ahmed, Shehta, Ahmed, Shirazi, Ahmed, Mohamed, Ahmed Mohamed Ibrahim, Sherif, Ahmed Elshawadfy, Awad, Ahmed K, Abbas, Ahmed M, Abdelrahman, Ahmed Saber, Ammar, Ahmed Siddique, Azzam, Ahmed Y, Ciftci, Ahmet Burak, Dural, Ahmet Cem, Sanli, Ahmet Necati, Rahy-Martín, Aida Cristina, Tantri, Aida Rosita, Khan, Aimal, Al-Touny, Aiman, Tariq, Aiman, Gmati, Aimen, Costas-Chavarri, Ainhoa, Auerkari, Aino, Landaluce-Olavarria, Aitor, Puri, Ajay, Radhakrishnan, Ajay, Ubom, Akaninyene Eseme, Pradhan, Akhilesh, Turna, Akif, Adepiti, Akinfolarin, Kuriyama, Akira, Kassam, Al-Faraaz, Hassouneh, Ala, El-Hussuna, Alaa, Habeebullah, Alaa, Ads, Alaa Mohamed, Mousli, Alaa, Biloslavo, Alan, Hoang, Alan, Kirk, Alan, Santini, Alasdair, Melero, Alba Vazquez, Calvache, Albaro José Nieto, Baduell, Albert, Chan, Albert, Abrate, Alberto, Balduzzi, Alberto, Sánchez, Alberto Cabañero, Navarrete-Peón, Alberto, Porcu, Alberto, Brolese, Alberto, Barranquero, Alberto G, Saibene, Alberto Maria, Adam, Albushra Altayeb, Vagge, Aldo, Maquilón, Alejandra Jara, Leon-Andrino, Alejandro, Sekulić, Aleksandar, Trifunovski, Aleksandar, Mako, Aleksandro, Bedada, Alemayehu Ginbo, Broglia, Alessandro, Coppola, Alessandro, Giani, Alessandro, Grandi, Alessandro, Iacomino, Alessandro, Moro, Alessandro, D’amico, Alessia, Malagnino, Alessia, Tang, Alethea, Doyle, Alex, Alfieri, Alex, Haynes, Alex, Wilkins, Alex, Baldwin, Alexander, Heriot, Alexander, Laird, Alexander, Lazarides, Alexander, O'connor, Alexander, Trulson, Alexander, Rokohl, Alexander Christopher, Caziuc, Alexandra, Triantafyllou, Alexandra, Anesi, Alexandre, Nikova, Alexandrina, Andrianakis, Alexandros, Charalabopoulos, Alexandros, Tsolakidis, Alexandros, Chirca, Alexandru, Arnaud, Alexis P, Narvaez-Rojas, Alexis Rafael, Kavalakat, Alfie, Spina, Alfio, Recordare, Alfonso, Annicchiarico, Alfredo, Conti, Alfredo, Mohammed, Alhassan Datti, Kocataş, Ali, Almhimid, Ali, Arnaout, Ali, Fahmy, Ali, Mangi, Ali, Modabber, Ali, Ulas, Ali Bilal, Mohamedahmed, Ali Yasen Y, Frontali, Alice, Moynihan, Alice, Yunus, Alif, Ahmad, Aline, Kent, Alistair J, Khamees, Almu'atasim, Ugwu, Aloy Okechukwu, Turan, Alparslan, Mohammed, Alsnosy Abdullah Khalefa, Navarro-Barrios, Alvaro, Yebes, Alvaro, De Sousa, Álvaro Francisco Lopes, Moreno, Amabelle, Sethi, Aman, Dawson, Amanda Caroline, Othman, Amani Alsayd Abdulsalam, Kaur, Amanjot, Wolde, Amanuel, Antonelli, Amedeo, Scifo, Amedeo, Alhamad, Ameen, Davis, Amelia, Alderazi, Amer, Harky, Amer, Mohammed-Durosinlorun, Amina, Seguya, Amina, Okhakhu, Amina, Chamakhi, Amine, Sebai, Amine, Souadka, Amine, Asla, Amir, Agrawal, Amit, Persad, Amit, Gupta, Amit, Elgazar, Amr, Kulkarni, Amruta, Coates, Amy, Bellés, Ana Ciscar, Hadzibegovic, Ana Danic, Jotic, Ana, Kowark, Ana, Martins, Ana, Pineda, Ana Mejía, Peral, Ana, Gollarte, Ana Sánchez, Senent-Boza, Ana, Camarena, Ana Isabel Avellaneda, Castaño-Leon, Ana M, Bravo, Ana Maria Minaya, Moro, Ana María Gimeno, Musina, Ana-Maria, Tapia-Herrero, Ana-María, Kothari, Anai, Gupta, 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general surgery ,acute care surgery ,Settore MED/18 - CHIRURGIA GENERALE ,climate change ,trauma ,Settore MED/40 - Ginecologia E Ostetricia ,environmental impact ,surgery ,Settore MED/31 - Otorinolaringoiatria ,None ,Medicine and Health Sciences ,Surgery ,operating theatre ,environment - Abstract
Background: Healthcare cannot achieve net-zero carbon without addressing operating theatres. The aim of this study was to prioritize feasible interventions to reduce the environmental impact of operating theatres. Methods: This study adopted a four-phase Delphi consensus co-prioritization methodology. In phase 1, a systematic review of published interventions and global consultation of perioperative healthcare professionals were used to longlist interventions. In phase 2, iterative thematic analysis consolidated comparable interventions into a shortlist. In phase 3, the shortlist was co-prioritized based on patient and clinician views on acceptability, feasibility, and safety. In phase 4, ranked lists of interventions were presented by their relevance to high-income countries and low-middle-income countries. Results: In phase 1, 43 interventions were identified, which had low uptake in practice according to 3042 professionals globally. In phase 2, a shortlist of 15 intervention domains was generated. In phase 3, interventions were deemed acceptable for more than 90 per cent of patients except for reducing general anaesthesia (84 per cent) and re-sterilization of 'single-use' consumables (86 per cent). In phase 4, the top three shortlisted interventions for high-income countries were: introducing recycling; reducing use of anaesthetic gases; and appropriate clinical waste processing. In phase 4, the top three shortlisted interventions for low-middle-income countries were: introducing reusable surgical devices; reducing use of consumables; and reducing the use of general anaesthesia. Conclusion: This is a step toward environmentally sustainable operating environments with actionable interventions applicable to both high- and low-middle-income countries.
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- 2023
12. Non-invariants may be used for socially-relevant perceptual decisions
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Francesco Lacquaniti, Barbara La Scaleia, and Myrka Zago
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Artificial Intelligence ,General Physics and Astronomy ,General Agricultural and Biological Sciences - Published
- 2023
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13. Analgesia em pacientes submetidos à craniotomia: novas evidências para o alívio da dor
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Brendo Bezerra Bevenuto, Ana Livia Zago Rufo, Letícia Karen Rodrigues De Souza, Ana Tayres Santana Gomes Fontenele, Gabriel Teixeira Brito, Mariana Leocadio de Souza Bastos, Guilherme Henrique Glinglani Condé De Oliveira, José Ricardo Baracho dos Santos Júnior, Bruna Luiza da Silva Boaretto, Mércia Jubert Feitosa, Dayanne Beatriz Gomes Sampaio, Daiane Magalhães Malheiro, Andrew Pereira da Silva, and Priscila Moraes De Paula
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General Medicine - Abstract
A craniotomia se faz uma técnica terapêutica eficaz para doenças e lesões cerebrais, sendo a dor pós-operatória uma importante preocupação clínica nesse contexto, a qual atinge em torno de 86% dos pacientes submetidos à craniotomia. O presente estudo de revisão buscou avaliar novas evidências para o alívio da dor em pacientes submetidos à craniotomia, documentadas por meio de estudos clínicos e randomizados. Trata-se de uma pesquisa de revisão integrativa realizada por meio da base de dados PubMed, que levou em consideração os seguintes critérios de inclusão: ensaios clínicos e testes controlados e aleatórios; artigos publicados no último ano; que possuíam texto completo disponível e que abordassem acerca da analgesia em pacientes submetidos à craniotomia. Ficou constatado que a infiltração pós-operatória do couro cabeludo com bupivacaína pura reduz a intensidade da dor e a utilização de analgésicos opioides, sendo considerada uma técnica eficaz de controle da dor após uma craniotomia eletiva. Ademais, a combinação de ropivacaína com costicosteroides como o diprospan pode se tornar uma das estratégias utilizadas para controle da dor incisional em pacientes submetidos a craniotomia, conferindo à esta técnica a capacidade de promover alívio satisfatório da dor pós-operatória nesses pacientes. Por fim, foi verificado que, em comparação com a analgesia sistêmica, a analgesia regional pode auxiliar na redução da incidência e da gravidade da dor após uma craniotomia e a quantidade de analgesia de resgate usada em tais pacientes.
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- 2023
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14. Eficácia clínica de novas abordagens para o tratamento do transtorno de ansiedade generalizada
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Ana Livia Zago Rufo, Carolyne Lemos Marques, Elisa Anawate De Oliveira, Tatiana Póvoa Naves, Mayara dos Santos Barboteo Pinto, Radmila Martins Reginaldi, Bárbara Manha Utino, Arthur Gustavo Gouveia Marques Filho, Maurício Cavalcante Paixão, Mariana Moscon Gomes, Iollanda Nunes Faria, Cicero Alyson Dantas Sabóia, Matheus de Souza Teixeira, and Andrew Pereira Da Silva
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General Medicine - Abstract
O transtorno de ansiedade generalizada (TAG) é caracterizado por um distúrbio com características de ansiedade e preocupação excessivas, além de sintomas associados, sendo um dos transtornos de ansiedade mais prevalentes, com uma prevalência mundial estimada em torno de 6%. O presente estudo de revisão buscou avaliar novas evidências na abordagem terapêutica do transtorno de ansiedade generalizada, documentadas por meio de estudos clínicos e randomizados. Trata-se de uma pesquisa de revisão integrativa realizada por meio da base de dados PubMed, que levou em consideração os seguintes critérios de inclusão: ensaios clínicos e testes controlados e randomizados; artigos publicados no último ano; que possuíam texto completo disponível e que abordassem acerca de novas evidências no manejo do transtorno de ansiedade generalizada. Ficou constatado que a terapia de coloração pode trazer alívio nos sintomas de ansiedade e melhorias no humor positivo, reduzindo o humor negativo, o que eleva ainda mais os efeitos do tratamento dos pacientes com TAG. Além disso, a terapia comportamental dialética proporcionou uma melhora na função executiva dos pacientes com TAG, sendo uma medida eficaz na melhora de transtornos mentais e com boa capacidade para reduzir a gravidade de tais transtornos mentais. Outro ponto constatado é acerca do uso da tandospirona, em que o uso das doses de 60 mg/dia ou 30 mg/dia de tandospirona demonstraram eficácia promissora em pacientes com TAG. Por fim, foi visto que a doxepina em baixas doses possui boa eficácia terapêutica e tolerabilidade, fazendo-se um medicamento útil e racional para o manejo de tais pacientes.
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- 2023
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15. Perfil epidemiológico da malária no município de altamira
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Jéssica Sthefanye Urçulino Dorneles, Pedro Henrique Dorneles Silva, Beatriz Cristina da Silva Araújo, José Riccardo Ferrette Barreto, Ana Livia Zago Rufo, Pedro Henrique Zacarias Costa, Mariana Amorim Barbosa, and Jaiara Nascimento Bahia
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Marketing ,Pharmacology ,Organizational Behavior and Human Resource Management ,Strategy and Management ,Drug Discovery ,Pharmaceutical Science - Abstract
A malária é uma doença febril aguda causada por parasitas Plasmodium, sendo transmitida para as pessoas através da picada de mosquitos Anopheles fêmeas infectadas. A malária está contemplada no Objetivo 3 dos Objetivos do Desenvolvimento Sustentável (ODS) da Organização das Nações Unidas (ONU). O Brasil é o país em que se mais registram casos de malária, aproximadamente metade das ocorrências no continente americano. Diante do exposto acima, o presente trabalho surgiu com a finalidade de resposta o seguinte questionamento: qual a situação epidemiológica da malária no município de Altamira-PA, no período de 2011 a 2021. Foi feito um estudo descritivo, transversal e retrospectivo dos casos confirmados de Malária de 2011 até 2021 notificados no município de Altamira, considerando-se apenas os casos confirmados. Os dados foram obtidos por meio das fichas de notificação dos casos a partir do (SIVEP-Malária) que estão disponíveis no portal eletrônico. Durante o período analisado, foram confirmados 6018 casos no município de Altamira. Os maiores índices ocorreram entre os anos de 2011 e 2012, o que representa 54.17 % dos casos positivos. Entre os anos de 2013 e 2017, houve uma redução progressiva no número casos notificados de malária no município em questão, contudo a partir de 2018 os casos voltaram a crescer.
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- 2023
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16. Análise da Estabilidade de Cor e Brilho de Materiais Restauradores de Incremento Único Expostos a Bebida Corante e Ácida
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Taísa Freitas Zago, André Luiz Fraga Briso, Yasmine Parischi Musa Ali, Érika Mayumi Omoto, Diego Felipe Mardegan Gonçalves, Silvio José Mauro, and Ticiane Cestari Fagundes
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General Medicine - Abstract
A inserção de incrementos únicos é uma característica vantajosa no que se refere à redução do tempo de procedimento clínico. Dessa forma, o objetivo deste estudo foi avaliar a estabilidade de cor e brilho de materiais restauradores de incremento único expostos à bebida corante e ácida. Foram avaliados dois tipos de resina composta, uma de inserção incremental (FT) e outra de incremento único (BK); assim como, dois cimentos ionoméricos de alta viscosidade, um sem cobertura de proteção (KT) e outro com cobertura de proteção com carga nanoparticulada (EQ). Para cada material restaurador foram confeccionados 26 discos (5 mm de diâmetro e 4 mm de espessura), totalizando 104 corpos de prova. Os espécimes foram aleatoriamente divididos em subgrupos para as seguintes imersões: saliva artificial e Coca-Cola. Foi avaliada a alteração de cor e brilho entre os diferentes tipos de materiais, antes e após as imersões propostas. Os dados obtidos para alteração de cor e brilho foram submetidos ao teste de análise de variância dois critérios e o brilho foi avaliado pela análise de variância dois critérios medidas repetidas. Para todas as análises foi realizado o pós-teste de Tukey, com nível de significância de 5%. Com relação aos resultados de cor, a resina FT apresentou maior alteração do que BK em Coca-cola, sendo que para saliva o oposto ocorreu. Já para os cimentos ionoméricos, o KT obteve a maior alteração em Coca-Cola. Não houve diferença estatística entre as resinas para alteração de brilho, no entanto, KT apresentou maior alteração quando imerso em Coca-Cola do que saliva. Desse modo conclui-se que a resina composta de inserção única sofreu menos a ação da bebida corante e ácida na alteração de cor. Para os CIVs, KT apresentou maior alteração cromática e de brilho, quando comparado ao EQ. Assim, a cobertura nanoparticulada forneceu proteção adicional ao material restaurador híbrido.
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- 2023
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17. Toxicity of recommended insecticides for the tomato culture on Trichogramma pretiosum Riley, 1879 (Hymenoptera: Trichogrammatidae)
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Vinícius Pereira Dos Santos, Alixelhe Pacheco Damascena, Dirceu Pratissoli, José Romário De Carvalho, Regiane Cristina Oliveira de Freiras Bueno, Hugo Bolsoni Zago, Jéssica Barboza Pereira, and Diná Vimercati Oliveira
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Earth-Surface Processes - Abstract
The biological control and use of insecticides need to be compatible in order to preserve the community of insects that is beneficial for the production system. Therefore, the aim of this study was to assess the alterations of biological characteristics of Trichogramma pretiossum Riley, 1879 (Hymenoptera: Trichogrammatidae), when submitted to the parasitism of Anagasta kuehniella eggs (Zeller, 1879) (Lepidoptera: Pyralidae) treated with insecticides recommended for the tomato culture for selectivity tests. The experiment was conducted at the Nucleus for Scientific and Technological Development in Phytosanitary Management (NUDEMAFI) in climate-controlled chambers at the temperature of 15±1ºC, relative humidity of 70±10%, and photophase of 14 hours. One newly emerged T. pretiosum female was used in each Eppendorf tube containing a card with 20 unviable eggs of A. kuehniella host, which were previously emerged in insecticide syrup. Fifteen repetitions were conducted for each treatment. The eggs were submitted to parasitism for 24 hours and after the descendants emerged, the characteristics were verified for biological parasitism and development of individuals. Insecticides with active ingredients Piriproxifen, Teflubenzuron, Acetamiprid 1, Lambda- Cyalothrin and Chlorantraniliprole + Lambda-Cyalothrin were considered the most selective for parasitoid T. pretiosum.
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- 2023
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18. Action of fungicide recommended for the tomato culture on Trichogramma pretiosum Riley, 1879 (Hymenoptera: Trichogrammatidae)
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Vinícius Pereira Dos Santos, Alixelhe Pacheco Damascena, Dirceu Pratissoli, José Romário De Carvalho, Regiane Cristina Oliveira de Freiras Bueno, Hugo Bolsoni Zago, Jéssica Barboza Pereira, and Diná Vimercati Oliveira
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Earth-Surface Processes - Abstract
The aim of this study was to evaluate the possible alterations of biological characteristics of Trichogramma pretiossum (Riley, 1879) (Hymenoptera: Trichogrammatidae) submitted to the parasitism of Anagasta kuehniella (Zeller, 1879) (Lepidoptera: Pyralidae) eggs treated with fungicide registered for the tomato culture in selectivity tests using the methodology suggested by the IOBC/WPRS for selectivity studies. A total of 29 fungicides were evaluated in the experiments performed at the Nucleus for Scientific and Technological Development in Phytosanitary Management (NUDEMAFI). Cards with 20 host eggs were immersed in fungicide syrup and submitted to parasitism for 24 hours. After the incubation period for the parasitoid and their emergence the fungicide effects were assessed for the biological characteristics of the parasitism. We concluded that the fungicides Supera® (COPPER HYDROXIDE 537.4g/L), Nativo® (TEBUCONAZOLE 200g/L + TRIFLOXYSTROBIN 100g/L), Censor® (FENAMIDONE 500g/L), Manzate 800® (MANCOZEB 800g/Kg), Captan SC® (CAPTAN 480g/L), Amistar 500 WG® (AZOXYSTROBIN 500g/Kg), Frowncide 500 SC® (FLUAZINAM 500g/L), Fegatex® (BENZALKONIUM CHLORIDE 100g/L), Redshield 750® (CUPROUS OXIDE 860g/Kg), Proplant® (PROPAMOCARB CHLORIDE 722g/L), Isatalonil 500 SC® (CHLOROTHALONIL 750g/Kg), Recop® (DICOPPER CHLORIDE TRIHYDROXIDE 840g/Kg), Bion 500 WG® (ACIBENZOLAR-S-METHYL 500g/Kg) and Curzate BR® (CYMOXANIL 80g/Kg + MANCOZEB 640g/Kg) presented better results for selectivity in the T. pretiosum parasitoid.
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- 2023
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19. A study of the anisotropy of dimensional change in the compaction plane during sintering of low alloyed cold compacted steels
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Onur Utku Uçak, Marco Zago, Juergen Voglhuber, and Ilaria Cristofolini
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Mechanics of Materials ,Materials Chemistry ,Metals and Alloys ,Ceramics and Composites ,Condensed Matter Physics - Published
- 2023
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20. Source Matching and Rewriting for MLIR Using String-Based Automata
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Vinicius Espindola, Luciano Zago, Hervé Yviquel, and Guido Araujo
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Hardware and Architecture ,Software ,Information Systems - Abstract
A typical compiler flow relies on a uni-directional sequence of translation/optimization steps that lower the program abstract representation, making it hard to preserve higher-level program information across each transformation step. On the other hand, modern ISA extensions and hardware accelerators can benefit from the compiler’s ability to detect and raise program idioms to acceleration instructions or optimized library calls. Although recent works based on Multi-Level IR (MLIR) have been proposed for code raising, they rely on specialized languages, compiler recompilation, or in-depth dialect knowledge. This article presents Source Matching and Rewriting (SMR), a user-oriented source-code-based approach for MLIR idiom matching and rewriting that does not require a compiler expert’s intervention. SMR uses a two-phase automaton-based DAG-matching algorithm inspired by early work on tree-pattern matching. First, the idiom Control-Dependency Graph (CDG) is matched against the program’s CDG to rule out code fragments that do not have a control-flow structure similar to the desired idiom. Second, candidate code fragments from the previous phase have their Data-Dependency Graphs (DDGs) constructed and matched against the idiom DDG. Experimental results show that SMR can effectively match idioms from Fortran (FIR) and C (CIL) programs while raising them as BLAS calls to improve performance. Additional experiments also show performance improvements when using SMR to enable code replacement in areas like approximate computing and hardware acceleration.
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- 2023
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21. <scp>Two‐Year</scp> observational study of autonomic skin function in patients with Parkinson's disease compared to healthy individuals
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Timo Siepmann, Martin Arndt, Annahita Sedghi, Szabolcs Szatmári, Tamás Horváth, Annamária Takáts, Dániel Bereczki, Mats Leif Moskopp, Sylvia Buchmann, Cornelia Skowronek, Wagner Zago, Warunya Woranush, Razvan Lapusca, Marie Luise Weidemann, Christopher H. Gibbons, Roy Freeman, Heinz Reichmann, Volker Puetz, Kristian Barlinn, Alexandra Pintér, and Ben Min‐Woo Illigens
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Neurology ,Neurology (clinical) - Published
- 2023
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22. Participação do acompanhante no contexto do nascimento: revisão integrativa
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Carolina Pacheco Araújo, Alessandro Trevisan Monteiro, Bianca dos Santos Lima, Cristina Saling Kruel, Maittê Vargas Zago, and Regina Gema Santini Costenaro
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General Medicine - Abstract
Objetivos: Conhecer as produções científicas da área da enfermagem acerca da participação do acompanhante de livre escolha da parturiente no parto e nascimento. Método: Revisão do estado da arte por meio de uma revisão integrativa. A coleta de dados foi realizada no período de outubro e novembro de 2017 nas bases de dados BVS e Pubmed nos idiomas espanhol, inglês e português. Resultados: Foram selecionados 18 artigos para a revisão. Após leitura e reflexões realizadas acerca das publicações científicas elencadas, emergiram três categorias: “Acompanhante no parto: percepção dos profissionais de saúde”; “Acompanhante no parto: voz da parturiente”; “Desconstruindo a hegemonia feminina do parto: ele está comigo”. Considerações finais: É necessário transcender barreiras, sejam elas institucionais, pessoais ou de modelos ultrapassados de assistência ao parto. Os processos de atenção ao parto requerem uma nova forma de gestão e de cuidado, viabilizando o diálogo e a participação ativa de todos os envolvidos no processo do nascimento.
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- 2023
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23. As manifestações clínicas do portador de paralisia facial
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Marina Gabriela Magalhães Barbosa Murta, Ana Karine Laranjeira De Sá, Valdirene Pereira da Silva Carvalho, Louyse Isabelle Vieira Garcia, Gabriela Nogueira Couto, Virgínnia Tereza Zago Chies, Layo Leite De Lucena, Alisson Fernando Dos Santos, Arthur Hayasi Maniero, Viviane Raquel Gonçalves Medeiros, Aloysio Soares Santos, José Songlei da Silva Rocha, Cibele Bessa Pacheco, Pedro Eduardus Leal, Alice Aparecida Morais Santos, Bibiana Aparecida Pereira, Taís Fernanda Da Silva, Bernardo Pinto Coelho de Carvalho Corrêa, Jayane da Silva Oliveira Linhares, Lucas Arruda de Souza, Katia Aparecida Scarpari Bourdokan, Daniel Victor Viana Rodrigues Nunes, Raphael Patrik Borges Da Costa, Lorenna Rocha Rodrigues, Carolina Scherer Dornelles, Pedro Paulo Rizerio de Carvalho Teixeira, Daniel Batista Chaves, Danilo Pigosso Marciano, Uanderson Pereira da Silva, Larissa Luciana Pires Silva, Alvim João Faust, Leandro Westphal, Lucas Carneiro Dos Santos, Guilherme Silva Malheiros, Luiz Augusto Germano Borges, Luciano da Silva Alves, Gilmar Rosado Hurtado, Mariana Monteiro Resende, Gabriella Amâncio Matos, and Rodrigo Daniel Zanoni
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Marketing ,Pharmacology ,Organizational Behavior and Human Resource Management ,Strategy and Management ,Drug Discovery ,Pharmaceutical Science - Abstract
Introdução: A paralisia facial e um sintoma de um transtorno de base resultante em imobilidade e incapacidade de executar a mímica facial e a expressão emotiva. São várias as etiologias deste acometimento, sendo a classificação em paralisia facial periférica, representada classicamente pela paralisia de Bell e a central, pelo acidente vascular encefálico, adotada para auxiliar na investigação e seguimento clínico adequado. Objetivo: Descrever sobre a paralisia facial, com foco em características clínicas que propiciem ao diagnóstico precoce, medidas terapêuticas e restauração imediata. Metodologia: Revisão narrativa que selecionou artigos disponibilizados na íntegra publicados no recorte temporal de 2008 até 2022. Resultados: Dos 10 artigos incluídos neste estudo, todos realizaram uma ampla análise sobre a temática, a qual propiciou a disseminação de informações atualizadas sobre conceito, diagnóstico diferencial entre duas condições clínicas opostas resultantes em paralisia facial, manifestações, avaliação clínica e manejo adequado. Conclusão: Estudos ainda urgem em ser feitos no intuito de orientar melhor os profissionais e a comunidade a respeito da paralisia facial e a importância que possui o acompanhamento e seguimento precoce. Destarte, é
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- 2023
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24. Principais doenças parasitárias e infecciosas em equinos do Pantanal
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Daniel Zacharias Zago, Valeria Castilho Onofrio, Herbert Sousa Soares, and Arlei Marcili
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Marketing ,Pharmacology ,Organizational Behavior and Human Resource Management ,Strategy and Management ,Drug Discovery ,Pharmaceutical Science - Abstract
O bioma Pantanal possui grande diversidade de fauna e flora, além de ser a maior planície alagável do mundo. Intercala períodos de chuva e seca, proporcionando o ambiente ideal para a proliferação de vetores e patógenos. O cavalo é de fundamental importância nos sistemas de produção de bovinos de corte, atuando no manejo do gado, como meio de transporte, principalmente nas regiões de difícil acesso. Não menos importante, é peça fundamental para o ecoturismo na região, atividade cada dia mais explorada. Estes animais podem entrar em contato com diversos agentes que podem causar doenças, como hemoparasitoses, anemia infecciosa e pitiose, que embora sejam frequentes na rotina clínica, são muitas vezes negligenciadas e responsáveis por grandes prejuízos econômicos. O presente trabalho de revisão de literatura tem como objetivo abordar os diversos aspectos dessas afecções, como etiologia, epidemiologia, patogenia e sintomatologia clínica, contemplando também diagnóstico, terapêutica, medidas de controle e profilaxia.
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- 2023
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25. Ethyl Acetate Fraction of Harpagophytum procumbens Prevents Oxidative Stress In Vitro and Amphetamine-Induced Alterations in Mice Behavior
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Valtieri Bortoluzzi Lima, Altevir Rossato Viana, Daniel Santos, Narieli Felipetto, Natália Fernandes Mezzomo, Adriana Maria Zago, Erico Marlon Moraes Flores, Alencar Kolinski Machado, Alexandre Krause, Luis Ricardo Peroza, Larissa Finger Schaffer, and Luciana Maria Fontanari Krause
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Cellular and Molecular Neuroscience ,General Medicine ,Biochemistry - Published
- 2023
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26. Thoracogenic scoliosis: coronal deformity progression in paediatric patients
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Riccardo Sacco, Mourad Ould-Slimane, Michel Bonnevalle, Eric Nectoux, Alessandra Zago, Franck Dujardin, and Federico Canavese
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Orthopedics and Sports Medicine ,Surgery - Abstract
To assess the risk of developing thoracogenic scoliosis (THS) in paediatric patients, depending on the side of lateral thoracotomy (LT) and of spine deviation in the coronal plane by means of logistic regression and scoliosis-free survival analyses.A total of 307 consecutive patients undergoing LT were retrospectively reviewed; 32 patients met the inclusion criteria: 1) underwent LT and developed THS; 2) age 15 years at LT; 3) clinical and radiographic follow-up ≥ 5 years. Patients were divided into ipsilateral group (convexity ipsilateral to LT) and contralateral group (convexity contralateral to LT).The mean follow-up was 10 ± 4.7 in the ipsilateral group (n = 13) and 12 ± 4.8 years in the contralateral group (n = 19). The contralateral group underwent LT at a younger age (4.4 vs 6.4 years, p = 0.55), developed more severe coronal deformity (27.8° vs 18.9°, p = 0.15), had higher rate of THS 20° (47.5% vs 38.4%; p = 0.34) and 45° (21.1% vs 0%; p = 0.99). The mean time from LT to THS diagnosis was 4.2 ± 2.9 in ipsilateral group and 5.5 ± 4.2 years in contralateral group. Left-side LT (p = 0.03) and age 5 years (p = 0.01) showed a lower risk of THS diagnosis. The group variable had a statistically significant effect on the risk of developing THS 45° (p = 0.03).In this series, children that developed THS with a convexity contralateral to the side of LT had more severe and progressive coronal spine deformity.III.
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- 2023
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27. PERCEPÇÃO DE PROFESSORES DE EDUCAÇÃO INFANTIL E ENSINO FUNDAMENTAL SOBRE A ATUAÇÃO DO PSICÓLOGO NA EDUCAÇÃO SEXUAL DENTRO DO AMBIENTE ESCOLAR
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Elaine Alves Pereira, Ana Paula Guaitaneli Hommerding, Luiza Martins Calça, and Rafaela Zago de Mello
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General Medicine - Abstract
Este estudo teve como intuito realizar uma pesquisa com os professores de educação infantil e ensino fundamental, das escolas públicas, de um município no Oeste do Paraná, com o objetivo de identificar a postura do professor frente ao tema sexualidade com crianças, analisar quais os empecilhos que os professores enfrentam ao abordar o tema e investigar quanto à necessidade de um psicólogo contribuindo na educação sexual infantil. A escolha da temática, foi investigar a atuação do psicólogo nas escolas na rede pública do município de Foz do Iguaçu. O referencial teórico da presente pesquisa foi estruturado em dois tópicos, a saber: sexualidade dentro do ambiente escolar e a importância do psicólogo dentro da escola. O método utilizado na pesquisa foi levantamento de dados bibliográficos e pesquisa quali-quantitativa, sendo que a coleta de dados foi realizada através de um formulário online pela plataforma Google Forms, elaborado pelas pesquisadoras, contendo ao total 14 perguntas. Participaram da pesquisa 26 educadores entre 20 e 60 anos de idade que estavam no mínimo um ano efetivos em sala de aula da Educação Infantil e Ensino Fundamental de escolas municipais. Constatou-se que a maioria dos educadores é a favor do psicólogo no ambiente escolar. Constatado também que os educadores encontram dificuldades para abordar o tema sexualidade, sendo que a maioria dos entrevistados declararam não ter recebido nenhuma orientação ou capacitação sobre o tema, do qual precisa ser abordado de forma coesa, em todos os aspectos sociais.
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- 2023
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28. Liver stiffness measurement by vibration-controlled transient elastography improves outcome prediction in primary biliary cholangitis
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Christophe Corpechot, Fabrice Carrat, Farid Gaouar, Frederic Chau, Gideon Hirschfield, Aliya Gulamhusein, Aldo J. Montano-Loza, Ellina Lytvyak, Christoph Schramm, Albert Pares, Ignasi Olivas, John E. Eaton, Karim T. Osman, George Dalekos, Nikolaos Gatselis, Frederik Nevens, Nora Cazzagon, Alessandra Zago, Francesco Paolo Russo, Nadir Abbas, Palak Trivedi, Douglas Thorburn, Francesca Saffioti, Laszlo Barkai, Davide Roccarina, Vicenza Calvaruso, Anna Fichera, Adèle Delamarre, Esli Medina-Morales, Alan Bonder, Vilas Patwardhan, Cristina Rigamonti, Marco Carbone, Pietro Invernizzi, Laura Cristoferi, Adriaan van der Meer, Rozanne de Veer, Ehud Zigmond, Eyal Yehezkel, Andreas E. Kremer, Ansgar Deibel, Jérôme Dumortier, Tony Bruns, Karsten Große, Georges-Philippe Pageaux, Aaron Wetten, Jessica Dyson, David Jones, Olivier Chazouillères, Bettina Hansen, Victor de Lédinghen, Corpechot, Christophe, Carrat, Fabrice, Gaouar, Farid, Chau, Frederic, Hirschfield, Gideon, Gulamhusein, Aliya, Montano-Loza, Aldo J, Lytvyak, Ellina, Schramm, Christoph, Pares, Albert, Olivas, Ignasi, Eaton, John E, Osman, Karim T, Dalekos, George, Gatselis, Nikolao, Nevens, Frederik, Cazzagon, Nora, Zago, Alessandra, Russo, Francesco Paolo, Abbas, Nadir, Trivedi, Palak, Thorburn, Dougla, Saffioti, Francesca, Barkai, Laszlo, Roccarina, Davide, Calvaruso, Vincenza, Fichera, Anna, Delamarre, Adèle, Medina-Morales, Esli, Bonder, Alan, Patwardhan, Vila, Rigamonti, Cristina, Carbone, Marco, Invernizzi, Pietro, Cristoferi, Laura, van der Meer, Adriaan, de Veer, Rozanne, Zigmond, Ehud, Yehezkel, Eyal, Kremer, Andreas E, Deibel, Ansgar, Dumortier, Jérôme, Bruns, Tony, Große, Karsten, Pageaux, Georges-Philippe, Wetten, Aaron, Dyson, Jessica, Jones, David, Chazouillères, Olivier, Hansen, Bettina, de Lédinghen, Victor, Corpechot, C, Carrat, F, Gaouar, F, Chau, F, Hirschfield, G, Gulamhusein, A, Montano-Loza, A, Lytvyak, E, Schramm, C, Pares, A, Olivas, I, Eaton, J, Osman, K, Dalekos, G, Gatselis, N, Nevens, F, Cazzagon, N, Zago, A, Russo, F, Abbas, N, Trivedi, P, Thorburn, D, Saffioti, F, Barkai, L, Roccarina, D, Calvaruso, V, Fichera, A, Delamarre, A, Medina-Morales, E, Bonder, A, Patwardhan, V, Rigamonti, C, Carbone, M, Invernizzi, P, Cristoferi, L, van der Meer, A, de Veer, R, Zigmond, E, Yehezkel, E, Kremer, A, Deibel, A, Dumortier, J, Bruns, T, Große, K, Pageaux, G, Wetten, A, Dyson, J, Jones, D, Chazouillères, O, Hansen, B, de Lédinghen, V, and Gastroenterology & Hepatology
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Liver Cirrhosis ,FibroScan ,Mortality ,PBC ,Prognosis ,Transplantation ,Hepatology ,Prognosi ,Liver Cirrhosis, Biliary ,Liver Cirrhosi ,Vibration ,Follow-Up Studie ,Cohort Studies ,Liver ,Elasticity Imaging Technique ,Retrospective Studie ,Humans ,Elasticity Imaging Techniques ,Cohort Studie ,Retrospective Studies ,Follow-Up Studies ,Human - Abstract
BACKGROUND & AIMS: Liver stiffness measurement (LSM) by vibration-controlled transient elastography (VCTE) has been shown to predict outcomes of patients with primary biliary cholangitis (PBC) in small-size studies. We aimed to validate the prognostic value of LSM in a large cohort study. METHODS: We performed an international, multicentre, retrospective follow-up study of 3,985 patients with PBC seen at 23 centres in 12 countries. Eligibility criteria included at least 1 reliable LSM by VCTE and a follow-up ≥ 1 year. Independent derivation (n = 2,740) and validation (n = 568) cohorts were built. The primary endpoint was time to poor clinical outcomes defined as liver-related complications, liver transplantation, or death. Hazard ratios (HRs) with CIs were determined using a time-dependent multivariable Cox regression analysis. RESULTS: LSM was independently associated with poor clinical outcomes in the derivation (5,324 LSMs, mean follow-up 5.0 ± 3.1 years) and validation (1,470 LSMs, mean follow-up 5.0 ± 2.8 years) cohorts: adjusted HRs (95% CI) per additional kPa were 1.040 (1.026-1.054) and 1.042 (1.029-1.056), respectively (p
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- 2022
29. Telephone-based Frontal Assessment Battery (t-FAB): standardization for the Italian population and clinical usability in neurological diseases
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Edoardo Nicolò Aiello, Veronica Pucci, Lorenzo Diana, Aida Niang, Alice Naomi Preti, Adriana Delli Ponti, Gaia Sangalli, Stefano Scarano, Luigi Tesio, Stefano Zago, Teresa Difonzo, Ildebrando Appollonio, Sara Mondini, Nadia Bolognini, Aiello, E, Pucci, V, Diana, L, Niang, A, Preti, A, Delli Ponti, A, Sangalli, G, Scarano, S, Tesio, L, Zago, S, Difonzo, T, Appollonio, I, Mondini, S, and Bolognini, N
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MED/26 - NEUROLOGIA ,Aged, 80 and over ,Male ,Aging ,Reproducibility of Results ,Frontal assessment battery ,Teleneurology ,Neuropsychological Tests ,Reference Standards ,M-PSI/02 - PSICOBIOLOGIA E PSICOLOGIA FISIOLOGICA ,Telephone ,Stroke ,Telephone-based ,Executive Function ,M-PSI/03 - PSICOMETRIA ,Humans ,Nervous System Diseases ,Geriatrics and Gerontology ,Executive functioning ,Cognitive screening ,Neurological disease ,Aged - Abstract
Background Despite the relevance of telephone-based cognitive screening tests in clinical practice and research, no specific test assessing executive functioning is available. The present study aimed at standardizing and providing evidence of clinical usability for the Italian telephone-based Frontal Assessment Battery (t-FAB). Methods The t-FAB (ranging 0–12), comprising two subtests, has two versions: one requiring motor responses (t-FAB-M) and the other verbal responses (t-FAB-V). Three hundred and forty-six Italian healthy adults (HPs; 143 males; age range = 18–96 years; education range = 4–23 years) and 40 participants with neurological diseases were recruited. To HPs, the t-FAB was administered along with a set of telephone-based tests: MMSE, verbal fluency (VF), backward digit span (BDS). The in-person version of the FAB was administered to both HPs and clinical groups. Factorial structure, construct validity, inter-rater and test–retest reliability, t-FAB-M vs. t-FAB-V equivalence and diagnostic accuracy were assessed. Norms were derived via Equivalent Scores. Results In HPs, t-FAB measures yielded high inter-rater/test–retest reliability (ICC = .78–.94), were internally related (p ≤ .005) and underpinned by a single component, converging with the telephone-based MMSE, VF, BDS (p ≤ .0013). The two t-FAB versions were statistically equivalent in clinical groups (ps of both equivalence bounds p p ≤ .004). t-FAB scores converge with the in-person FAB in HPs and clinical groups (rs = .43–.78). Both t-FAB versions were accurate in discriminating HPs from the clinical cohort (AUC = .73-.76). Discussion The t-FAB is a normed, valid, reliable and clinically usable telephone-based cognitive screening test to adopt in both clinical and research practice.
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- 2022
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30. Fetal inflammatory response syndrome (FIRS): che cosa è, quando bisogna pensarci
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Sara Tagliani, Luca Casadio, Ivana Bruno, Giulia Graziani, Caterina Radice, Silvia Zago, Giancarlo Piccinini, and Federico Marchetti
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Geography, Planning and Development ,Management, Monitoring, Policy and Law - Abstract
The paper describes a case of severe hyperleukocytosis in a preterm with FIRS (Fetal Inflammatory Response Syndrome) associated with funisitis of umbilical cord and intrauterine inflammation. FIRS is a cause of leukocytosis in newborn, as well as leukemoid reaction in 21 trisomy, congenital leukemia, sepsis and steroid prophylaxis. Inflammatory response syndrome is associated with high mortality, neuroevolutive impairment and complication of prematurity like intraventricular haemorrhage, chronic lung disease, periventricular leukomalacia and sepsis.
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- 2022
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31. Resposta satisfatória a quimioterapia em paciente com carcinoma de pequenas células de cavidade nasal
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Borges, Giovani Zago, Silva, Mariane Luisa Fonseca, Nascimento, Bruna Essado, Martins, Adriana Batista Alves, Souza, Gustavo Paranaiba de, Sousa, Ana Luisa Rufino de, and Pazinato, Elisangela Ferraz
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Carcinoma de Células Pequenas ,General Medicine ,radioterapia ,quimioterapia ,cavidade nasal - Abstract
O carcinoma extrapulmonar de pequenas células é um tumor agressivo e raro, com prognóstico sombrio e tratamento semelhante com seu homólogo pulmonar, possuem geralmente disseminação ao diagnóstico, com abordagem de acordo com sítio de localização e extensão, havendo bons resultados com uso de quimiorradioterapia. Paciente do sexo masculino, 39 anos, iniciou com quadro de obstrução nasal, lacrimejamento e turvação visual com exoftalmia, após investigação para o quadro, foi encontrado lesão sólida expansiva em região nasossinusal com efeito de massa, que, após análise imunohistoquímica concluiu tratar-se de EPSCC. Iniciado terapia com boa resposta logo no primeiro ciclo de quimioterapia, com alívio dos sintomas referidos. Apesar de raro e agressivo, o carcinoma de pequenas células apresenta similaridade ao mesmo tipo histológico pulmonar, que permite tratamento semelhante, porém, é fundamental a abordagem sobre o tema tendo em vista a otimização e individualização deste de acordo com o local de acometimento e benefícios ao paciente, em sua morbimortalidade.
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- 2022
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32. Decadência da autotutela administrativa: a proteção do ato administrativo e de seus efeitos jurídicos
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Floriano de Azevedo Marques Neto and Marina Fontão Zago
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General Medicine - Abstract
É inerente ao próprio conceito de ato administrativo a produção de efeitos jurídicos. Como, então, a autotutela — e, mais especificamente, a decadência da autotutela — impacta os efeitos gerados pelo ato administrativo em questão? O presente artigo defende que os efeitos jurídicos de um ato administrativo que se prolongam no tempo estão abarcados pelo instituto da decadência da autotutela e, assim, se devem ser preservados. Para isso, analisa os fundamentos da decadência da autotutela administrativa, como mecanismo estabilizador das relações sociais e concretizador da segurança jurídica, e delineia a lógica pela qual devem-se preservar os próprios efeitos do ato administrativo em questão. Em seguida, aplica essas considerações para um caso abstrato (porém bastante prático): o reequilíbrio econômico-financeiro de um contrato de concessão por meio de aumento tarifário. No caso, o reequilíbrio é contado a partir do reconhecimento do desequilíbrio financeiro; decorrido tal prazo, o aumento tarifário deverá ser preservado, conjuntamente com o ato em si que reconheceu o desequilíbrio.
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- 2022
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33. DEPOIMENTO ESPECIAL DE CRIANÇAS E ADOLESCENTES VÍTIMAS DE VIOLÊNCIA SEXUAL
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Joao Vitor da Silva Batista and Tanise Zago Thomasi
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General Medicine - Abstract
Considerando a vulnerabilidade de crianças e adolescentes vitimados de violência sexual e a necessidade de serem ouvidos adequadamente nos processos judiciais, o Brasil promulgou a Lei 13.431/17, resguardando a complexidade da oitiva de menores e suas consequências psicológicas na extração das necessárias informações. Nesta senda, o Poder Judiciário de Sergipe passou a utilizar o método do depoimento especial desde o ano de 2010, período em que o Conselho Nacional de Justiça (CNJ) recomendou a aplicabilidade daquele procedimento nos tribunais, (nº 33/2010), possuindo, assim, um tempo considerável de aplicação em anterioridade à citada lei. Utilizando-se do método analítico-comparativo das políticas adotadas nos âmbitos internacional e nacional e a aplicação do depoimento sem dano em momento anterior à lei 13.431/17, a pesquisa traçou sua metodologia a fim de verificar as políticas utilizadas pelo Judiciário de Sergipe para aplicação do depoimento sem dano mesmo antes da entrada em vigor da lei 13.431/17.
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- 2022
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34. Economic evaluation of plerixafor addition in the mobilization and leukapheresis of hematopoietic stem cells for autologous transplantation: a systematic review
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Roselene Mesquita Augusto Passos, Tallys Kalynka Feldens, Miriam Allein Zago Marcolino, Aline Sampaio Gouvêa, Lais Dos Santos Oliveira, Luisa Menardi Nasser, Roseli Fernandes Rodrigues, Leila de Lourdes Martins Perobelli, Alessandro Gonçalves Campolina, and Cesar de Almeida Neto
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Health Policy ,Pharmacology (medical) ,General Medicine - Published
- 2022
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35. Bacillus subtilis and Bacillus licheniformis promote tomato growth
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Peterson S. de O. Nunes, Flavio H. V. de Medeiros, Tiago Sebastião de Oliveira, Jaqueline R. de Almeida Zago, and Wagner Bettiol
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Media Technology ,Microbiology - Published
- 2022
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36. The 6th Albanian Congress of Trauma and Emergency Surgery
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Agron Dogjani, Arben Gjata, Xheladin Draçini, Etmont Çeliku, Carlos Mesquita, Juan Carlos Puyana, Mauro Zago, Hubert Hauser, Michael Pfeiffer, Valon M. Baraliu, Kastriot Haxhirexha, Arvin Dibra, Arben Beqiri, Kenan Karavdić, Alper Çelik, Ilir Hasani, Boris E. Sakakushev, Enton Bollano, Henri Kolani, Krenar Lilaj, Edvin Selmani, Erman Aytaç, Francesk Mulita, Nuhi Arslani, Myzafer Kaçaj, Georgios-Ioannis Verras, Elias Liolis, Ioannis Maroulis, Ioannis Perdikaris, Levan Tchabashvili, Panagiotis Perdikaris, Dariel Thereska, Admir Mustafa, Elona Markeci, Arta Karruli, Elona Çiku, Imri Vishi, Elmas Shaqiri, Amarildo Blloshmi, Aristidis-Elias Veves, Julian Ruci, Rabit Sadiku, Xhevdet Tahiraj, Skender Shabani, Leutrim Shabani, Bledi Masati, Halil Tanaj, Georgi Gelov, Alma Llukacaj Llukacaj, Marsela Ceno, Dieter Berger, Dietmar Paul, Ilir Shani, Alfred Ibrahimi, Saimir Kuci, Ervin Bejko, Stavri Llazo, Altin Veshti, Spiros Loggos, Sokol Xhepa, Jonela Burimi, Elvana Rista, Majlinda Naco, Pirro Prifti, Albi Fagu, Monika Belba, Kimete Kadesha, Natasha Merko, Skender Zatriqi, Enver Fekaj, Liri Ҫuko, Ardiana Sinani, Dorela Vasha, Ermira Muco, Eva Filaj, Vilma Cadri, Suela Mumajesi, Rudin Domi, Elida Agaci, Besnik Filaj, Driola Hoxha, Gentian Huti, Alma Cani, Blerim Arapi, Altin Papa, Artan Jahollari, Amarildo Hidri, Bledar Hodo, Genc Hyska, Jolanda Nikolla, Rinard Kortoci, Asead Abdyli, Mustafa Bajraktari, Edmond Zaimi, Isuf Bajrami, Yücel Sak, Aida Gavranović, Alisa Dudumi, Sadri Hulaj, Mehmet İşyar, Ilir Hasmuca, Ledian Fezollari, Irsadi Istemi Yucel, Rezeart Dalipi, Eris Nepravishta, Basri Lenjani, Esen Uysal, Katarina M. Kuzmanovic, Amel Mizić, Arben Rroji, Ilirian Laçi, Sonja Butorac (Saraçi), Vidi Demko, Bardha Dervishi, Helidon Nina, Albana Shahini, Edmond Gashi, Teona Bushati, Leart Berdica, Evis Gega, Erion Sukaj, Edmond Nuellari, Fadil Gradica, Ilir Skenduli, Petraq Mustaqe, Faton T. Hoxha, Andi Kacani, Edvin Prifti, Selman Dumani, Fation Hamiti, Kristi Saliaj, Erdem Degirmenci, Artan Bano, Sokol Isaraj, Gëzim Xhepa, Gentian Zikaj, Rezarta Kapaj, Vladimir Filaj, Nardi Kola, Desara Arapi, Deizi Dallndysha, Klea Beqiraj, Erblira Reshiti, Elona Hasalla, Ilda Taka, Brandi Fahriu, Haqif Gashi, Studim Hysa, Arvit Llazani, Ali Tonuzi, Besim Sermaxhaj, Monika Fida, Loreta Kuneshka, Besmira Zama, Hysni Dede, Muhamedin Rushiti, Gezim Galiqi, Saimir Heta, Arb Rexha, Matilda Imeraj, Danco Bizevski, Arsen Seferi, Artur Xhumari, Ridvan Alimehmeti, Esat Bardhoshi, Loreta Qemali, Edlira Zere, Remi Likaj, Erisa Kola, Albina Ndoja, Blerina Cela, Daniela Nakuci, Iva Saveta, Monika Kinolli, Petrit Biberaj, Ferizat Dika-Haxhirexha, Art Zylbeari, Elita Zylbeari-Masha, Edmond Pistulli, Klaudia Ferko, and Altin Habazaj
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General Materials Science - Abstract
After a three-year quarantine from the deadliest global pandemic of the last century, ASTES is organizing to gather all health professionals in Tirana, The 6th Albanian Congress of Trauma and Emergency Surgery(ACTES 2022) on 11-12 November 2022, with the topic Trauma & Emergency Surgery and not only...with the aim of providing high quality, the best standards, and the best results, for our patients ...ACTES 2022 is the largest event that ASTES (Albanian Society for Trauma and Emergency Surgery) has organized so far with 230 presentations, and 67 foreign lecturers with enviable geography, making it the largest national and wider scientific event.The scientific program is as strong as ever, thanks to the inclusiveness, where all the participants with a mix of foreign and local lecturers, select the best of the moment in medical science, innovation, and observation.The scientific committee has selected all the presentations so that the participants of each medical discipline will have something to learn, discuss, debate, and agree with updated methods, techniques, and protocols.I hope you will join us on Friday morning, and continue the journey of our two-day event together.
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- 2022
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37. Associação entre nível de priorização na admissão da unidade de terapia intensiva e desfecho hospitalar
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Ana Clara Donini Nazima, Amanda Pinheiro Zago, Cleber Barbieri, Daniel Luis Pires Rosa, Fabio Monti Juliani, Jair De Jesus Junior, Jessé Trinck Salvador, Julia Zanarde, Lucienne Tibery Queiroz Cardoso, Claudia Maria Dantas de Maio Carrilho, and Cintia Magalhães Carvalho Grion
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Objetivo: Avaliar a associação entre os níveis de priorização para admissão na unidade de terapia intensiva (UTI) e o prognóstico dos pacientes.Material e método: Estudo longitudinal retrospectivo que incluiu adultos internados na UTI de hospital universitário ano de 2020. As variáveis, coletadas nos prontuários e banco de dados eletrônicos do hospital contemplam: identificação, data de entrada no hospital e de admissão na UTI, diagnósticos, antecedentes, data de alta, desfecho, cálculo do Simplified Acute Physiology Score 3 (SAPS 3) e nível de priorização da admissão. Resultados: O estudo avaliou 274 pacientes. As patologias respiratórias totalizaram 41,25% das admissões, sendo COVID-19 o diagnóstico mais frequente (65 casos confirmados e 2 suspeitos). Dentre as comorbidades, destacam-se hipertensão arterial sistêmica (64,32%), diabetes mellitus (25,82%) e tabagismo (18,78%). O SAPS 3 médio foi de 59,29 pontos, representando uma probabilidade de óbito de 39,00%. A respeito dos níveis de priorizações, 174 (63,50%) pacientes foram classificados como prioridade 1 (P1); 94 (34,31%) pacientes como prioridade 2 (P2); e 6 (2,19%) pacientes como prioridade 3 (P3). Comparando os grupos P1 e P2, a probabilidade de óbito foi, respectivamente, 51,95% e 13,75%. E o número de óbitos observado foi de 90 (60,81%) no grupo P1 e 19 no grupo P2 (25,30%; p
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- 2022
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38. A multimodal imaging approach to foreign accent syndrome. A case report
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Greta Demichelis, Dunja Duran, Giuseppe Ciullo, Lorenzo Lorusso, Stefano Zago, Sara Palermo, Anna Nigri, Matilde Leonardi, Maria Grazia Bruzzone, and Davide Fedeli
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MEG ,Arts and Humanities (miscellaneous) ,DTI ,fMRI ,Neurology (clinical) ,Foreign accent syndrome ,resting-state fMRI - Abstract
This article describes a case of Foreign accent syndrome (FAS) in an Italian woman who developed a Canadian-like foreign accent without brain damage (functional FAS). The patient underwent an in-depth neuroimaging and (neuro)psychological evaluation. Language networks in the frontotemporal-parietal areas were typically activated bilaterally through fMRI and MEG assessments based on task-based data. Resting-state fMRI showed preserved connectivity between language areas. An obsessive-compulsive personality profile and mild anxiety were found, suggesting psychological and psychiatric factors may be relevant. Accordingly with our findings, multimodal imaging is beneficial to understand FAS neurological and functional etiologies.
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- 2022
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39. Modelagem matemática da eficiência térmica da soldagem a arco elétrico utilizando redes neurais artificiais
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Vagner Braga, Angelica Paola de Oliveira Lopes, Diego Tolotti de Almeida, Manuel Binelo, Maurício De Campos, Paulo Sérgio Sausen, Airam Teresa Zago Romcy Sausen, and Marcelo Maroski
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General Medicine - Abstract
Neste artigo é abordado o problema da estimativa da eficiência térmica da soldagem a arco elétrico, especialmente em relação ao processo \textit{Gas Metal Arc Welding}. Apesar de ser um parâmetro de grande relevância, a eficiência muitas vezes é determinada a partir de valores tabelados pelas normas técnicas, o que pode acabar prejudicando as análises metalúrgicas, visto que esses valores nem sempre conseguem contemplar todas as variações possíveis nos parâmetros da solda. Nesse contexto, neste artigo é proposto o desenvolvimento de um modelo matemático através de Redes Neurais Artificiais (RNAs) para ser utilizado em conjunto com um calorímetro de fluxo contínuo, a fim de se obter uma estimativa prévia para a eficiência e evitar despesas com ensaios experimentais que produziriam resultados abaixo do ideal. Os dados experimentais foram obtidos através de ensaios do processo de soldagem na empresa Bruning Tecnometal Ltda, e as simulações foram realizadas na ferramenta computacional Matlab. O modelo proposto foi validado por meio do método \textit{k-fold cross-validation} e apresentou baixo erro relativo médio.
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- 2022
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40. The role of the glypican and syndecan families of heparan sulfate proteoglycans in cardiovascular function and disease
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Lakshmi Narasimha Rao Thota and Andreia Zago Chignalia
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Syndecans ,Glypicans ,Physiology ,Membrane Proteins ,Receptors, Growth Factor ,Heparitin Sulfate ,Syndecan-1 ,Cell Biology ,Heparan Sulfate Proteoglycans ,Peptide Hydrolases - Abstract
Heparan sulfate proteoglycans (HSPGs) are proteoglycans formed by a core protein to which one or multiple heparan sulfate chains are covalently bound. They are ubiquitously expressed in cellular surfaces and can be found in the extracellular matrix and secretory vesicles. The cellular effects of HSPGs comprehend multiple functionalities that include 1) the interaction with other membrane surface proteins to act as a substrate for cellular migration, 2) acting as a binding site for circulating molecules, 3) to have a receptor role for proteases, 4) to act as a coreceptor that can provide finetuning of growth factor receptor activity threshold, and 5) to activate intracellular signaling pathways (Sarrazin S, Lamanna WC, Esko JD. Cold Spring Harb Perspect Biol 3: a004952, 2011). Among the different families of HSPGs, the syndecan and glypican families of HSPGs have gained increased attention in relation to their effects on cardiovascular cells and potential role in disease progression. In this review, we will summarize the effects of syndecan and glypican homologs on the different cardiovascular cell types and discuss their contribution to common processes found in cardiovascular diseases (inflammation, hypertrophy, and vascular remodeling) as well as their potential role in the development and progression of specific diseases including hypertension, heart failure, and atherosclerosis.
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- 2022
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41. The Otherworld (with)in This World: Imhet as a (Super)natural Conduit between Dimensions in Egyptian Sources
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Silvia Zago
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Cultural Studies ,Linguistics and Language ,Archeology ,General Arts and Humanities - Published
- 2022
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42. Text, Knowledge and Truth In the Duchy of Luxembourg, 1666-1781
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Zago, Tom
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history of historiography ,Luxembourg ,Luxembourg studies ,early modern Luxembourg ,cultures of knowledge ,Jesuit order - Abstract
This dissertation investigates the processes, procedures, and performances by which communities in the Habsburg Duchy of Luxembourg produced texts, generated knowledge and claimed truth between the first Marian election of 1666 and the centenary celebration of her patronage in 1781. The introduction identifies the Duchy as a contested historiographical entity and disputed spatial imaginary by revisiting the prejudices of traditional Luxembourgish scholarship, which has favoured teleological and progressivist interpretations of national genesis. Chapter I introduces the idea of the inauguration rite as the epitome of royal absenteeism and systemic component of the Duchy’s political culture. It establishes the main actors and proxy agents of the Duchy as a dominion of the Habsburg Monarchy and discusses the challenges they faced as well as the structural opportunities created most notably by the inauguration of Maria Theresa as Duchess of Luxembourg in 1744. Chapter II contrasts the previous discussion by demonstrating the political and logistical strains caused by royal visits in the second half of the eighteenth century. Adding depth to the local architecture of knowledge circulation, it demonstrates how a handful of actors succeeded in monopolising access to administrative and diplomatic knowledge. Chapter III observes the translation of knowledge into contemporary historiographical narratives, while slowly shifting our attention towards the temporalisation of a language of identity and community. Taking as its chronological scope the combined lifespan of the Jesuits Alexandre Wiltheim (1604-1684) and Jean Bertholet (1688-1750), the chapter discusses how knowledge remained firmly in the hands of a local elite. Chapter IV counters the logic of exclusivity of knowledge circulation embodied by Wiltheim and Bertholet by focusing on how it slowly migrated into the more stable – but politically destabilising – medium of print around the mid-eighteenth century. Chapter V returns to the seventeenth century and analyses how the Jesuits placed renewed emphasis on the figure of the Virgin Mary, thereby generating an alternative collective imaginary dominated by the Jesuit Order and enshrined in the Marian elections of 1666 and 1678. Chaper VI analyses how this Marian community answered changing political circumstances and shifting dynastic alliances in the early and mid-eighteenth century. Observing the translation of the Marian veneration into a post-Jesuit reality following the Order’s suppression in 1773, the core discussion centres around the centenary celebration of 1781 and how it negotiated the cult’s public nature anew. The conclusion will outline how, in the nineteenth century, these ceremonies and the truth they represented came to define the cornerstones of a Luxembourgish national sentiment and thus the hallmarks of a distinct state-formation process.
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- 2023
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43. Clinical features, therapeutic choice and response by phototype in psoriasis: analysis of the French PsoBioTeq cohort
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Salle-Siri, Romain, Tubach, Florence, Arlegui, Hugo, Curmin, Raphaëlle, Viguier, Manuelle, Beylot-Barry, Marie, Dupuy, Alain, Bénéton, Nathalie, Joly, Pascal, de Rycke, Yann, Jullien, Denis, Mahé, Emmanuel, Paul, Carle, Richard, Marie‐aleth, Bachelez, Hervé, Zago, Marilyn, Chosidow, Olivier, Sbidian, Emilie, Hôpital Henri Mondor, Institut Pierre Louis d'Epidémiologie et de Santé Publique (iPLESP), Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU), CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Hôpital Robert Debré, BoRdeaux Institute in onCology (Inserm U1312 - BRIC), Université de Bordeaux (UB)-Institut National de la Santé et de la Recherche Médicale (INSERM), CHU Pontchaillou [Rennes], Recherche en Pharmaco-épidémiologie et Recours aux Soins (REPERES), Université de Rennes (UR)-École des Hautes Études en Santé Publique [EHESP] (EHESP), Centre Hospitalier Le Mans (CH Le Mans), Physiopathologie, Autoimmunité, maladies Neuromusculaires et THErapies Régénératrices (PANTHER), Université de Rouen Normandie (UNIROUEN), Normandie Université (NU)-Normandie Université (NU)-Institut National de la Santé et de la Recherche Médicale (INSERM), Hospices Civils de Lyon (HCL), Centre Hospitalier Victor Dupouy, Institut Toulousain des Maladies Infectieuses et Inflammatoires (Infinity), Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), CHU Marseille, Imagine - Institut des maladies génétiques (IHU) (Imagine - U1163), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité), Dynamic Microbiology - EA 7380 (DYNAMIC), École nationale vétérinaire - Alfort (ENVA)-Agence nationale de sécurité sanitaire de l'alimentation, de l'environnement et du travail (ANSES)-Université Paris-Est (UPE)-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12), CIC - CHU Henri Mondor, and Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12)
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[SDV]Life Sciences [q-bio] - Abstract
International audience; BACKGROUND: Little is known about phototype and the response to systemic treatment in psoriasis. OBJECTIVE: To assess the characteristics of psoriasis, the therapeutic choice and its efficacy according to phototype. METHODS: We included patients from the PsoBioTeq cohort initiating a first biologic. Patients were classified according to their phototype. The evaluation included disease characteristics, choice of the initial biologic and therapeutic response at 12 months based on PASI 90 and DLQI 0/1. RESULTS: Of the 1400 patients included, 423 (30.2%), 904 (64.6%) and 73 (5.2%) were in the phototype I-II, III-IV and V-VI groups, respectively. The V-VI group had a higher initial DLQI, more frequently initiated ustekinumab. Patients in the phototype V-VI group maintained the first sequence of biologic as the other phototype groups, even though the proportion of patients reaching the PASI 90 and DLQI 0/1 at 12 months was lower in this group than other groups. CONCLUSION: Patient phototype seems associated with quality of life and choice of the initial biologic in psoriasis. Phototype V-VI group less frequently switched treatments than did the other groups when the response was not efficient.
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- 2023
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44. The Atacama Cosmology Telescope: High-resolution component-separated maps across one-third of the sky
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Coulton, William R., Madhavacheril, Mathew S., Duivenvoorden, Adriaan J., Hill, J. Colin, Abril-Cabezas, Irene, Ade, Peter A. R., Aiola, Simone, Alford, Tommy, Amiri, Mandana, Amodeo, Stefania, An, Rui, Atkins, Zachary, Austermann, Jason E., Battaglia, Nicholas, Battistelli, Elia Stefano, Beall, James A., Bean, Rachel, Beringue, Benjamin, Bhandarkar, Tanay, Biermann, Emily, Bolliet, Boris, Bond, J Richard, Cai, Hongbo, Calabrese, Erminia, Calafut, Victoria, Capalbo, Valentina, Carrero, Felipe, Chesmore, Grace E., Cho, Hsiao-mei, Choi, Steve K., Clark, Susan E., Rosado, Rodrigo Córdova, Cothard, Nicholas F., Coughlin, Kevin, Crowley, Kevin T., Devlin, Mark J., Dicker, Simon, Doze, Peter, Duell, Cody J., Duff, Shannon M., Dunkley, Jo, Dünner, Rolando, Fanfani, Valentina, Fankhanel, Max, Farren, Gerrit, Ferraro, Simone, Freundt, Rodrigo, Fuzia, Brittany, Gallardo, Patricio A., Garrido, Xavier, Givans, Jahmour, Gluscevic, Vera, Golec, Joseph E., Guan, Yilun, Halpern, Mark, Han, Dongwon, Hasselfield, Matthew, Healy, Erin, Henderson, Shawn, Hensley, Brandon, Hervías-Caimapo, Carlos, Hilton, Gene C., Hilton, Matt, Hincks, Adam D., Hložek, Renée, Ho, Shuay-Pwu Patty, Huber, Zachary B., Hubmayr, Johannes, Huffenberger, Kevin M., Hughes, John P., Irwin, Kent, Isopi, Giovanni, Jense, Hidde T., Keller, Ben, Kim, Joshua, Knowles, Kenda, Koopman, Brian J., Kosowsky, Arthur, Kramer, Darby, Kusiak, Aleksandra, La Posta, Adrien, Lakey, Victoria, Lee, Eunseong, Li, Zack, Li, Yaqiong, Limon, Michele, Lokken, Martine, Louis, Thibaut, Lungu, Marius, MacCrann, Niall, MacInnis, Amanda, Maldonado, Diego, Maldonado, Felipe, Mallaby-Kay, Maya, Marques, Gabriela A., van Marrewijk, Joshiwa, McCarthy, Fiona, McMahon, Jeff, Mehta, Yogesh, Menanteau, Felipe, Moodley, Kavilan, Morris, Thomas W., Mroczkowski, Tony, Naess, Sigurd, Namikawa, Toshiya, Nati, Federico, Newburgh, Laura, Nicola, Andrina, Niemack, Michael D., Nolta, Michael R., Orlowski-Scherer, John, Page, Lyman A., Pandey, Shivam, Partridge, Bruce, Prince, Heather, Puddu, Roberto, Qu, Frank J., Radiconi, Federico, Robertson, Naomi, Rojas, Felipe, Sakuma, Tai, Salatino, Maria, Schaan, Emmanuel, Schmitt, Benjamin L., Sehgal, Neelima, Shaikh, Shabbir, Sherwin, Blake D., Sierra, Carlos, Sievers, Jon, Sifón, Cristóbal, Simon, Sara, Sonka, Rita, Spergel, David N., Staggs, Suzanne T., Storer, Emilie, Switzer, Eric R., Tampier, Niklas, Thornton, Robert, Trac, Hy, Treu, Jesse, Tucker, Carole, Ullom, Joel, Vale, Leila R., Van Engelen, Alexander, Van Lanen, Jeff, Vargas, Cristian, Vavagiakis, Eve M., Wagoner, Kasey, Wang, Yuhan, Wenzl, Lukas, Wollack, Edward J., Xu, Zhilei, Zago, Fernando, and Zheng, Kaiwen
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Cosmology and Nongalactic Astrophysics (astro-ph.CO) ,FOS: Physical sciences ,Astrophysics - Cosmology and Nongalactic Astrophysics - Abstract
Observations of the millimeter sky contain valuable information on a number of signals, including the blackbody cosmic microwave background (CMB), Galactic emissions, and the Compton-$y$ distortion due to the thermal Sunyaev-Zel'dovich (tSZ) effect. Extracting new insight into cosmological and astrophysical questions often requires combining multi-wavelength observations to spectrally isolate one component. In this work, we present a new arcminute-resolution Compton-$y$ map, which traces out the line-of-sight-integrated electron pressure, as well as maps of the CMB in intensity and E-mode polarization, across a third of the sky (around 13,000 sq.~deg.). We produce these through a joint analysis of data from the Atacama Cosmology Telescope (ACT) Data Release 4 and 6 at frequencies of roughly 93, 148, and 225 GHz, together with data from the \textit{Planck} satellite at frequencies between 30 GHz and 545 GHz. We present detailed verification of an internal linear combination pipeline implemented in a needlet frame that allows us to efficiently suppress Galactic contamination and account for spatial variations in the ACT instrument noise. These maps provide a significant advance, in noise levels and resolution, over the existing \textit{Planck} component-separated maps and will enable a host of science goals including studies of cluster and galaxy astrophysics, inferences of the cosmic velocity field, primordial non-Gaussianity searches, and gravitational lensing reconstruction of the CMB., The Compton-y map and associated products will be made publicly available upon publication of the paper. The CMB T and E mode maps will be made available when the DR6 maps are made public
- Published
- 2023
45. Doença de Whipple e fator de risco em três relatos de caso
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Mateus Andre Rueda-Dantas, Beatriz Zago Gomes Rueda, Rovena Campana Tardin, Mariana Brasileiro Vieira Puppo, Paula Morette de Oliveira, Danielle Cristina Filgueira Alves Batista, Kethleen Gomes Wandekoken, Layni Storch, Lucas Zouain Figueiredo, Ludmilla Ventura Lirio, Caroline Alcure Pinto, Thiago Torezani, Leticia Goulart Campos, Luciana Lôfego Gonçalves, Izabelle Venturini Signorelli, and Maria da Penha Zago-Gomes
- Abstract
A Doença de Whipple é uma doença infecciosa crônica causada pela bactéria Tropheryma whipplei e é caracterizada por diarreia, artralgia, perda de peso e distúrbios neurológicos. A infecção ocorre mais frequentemente em pacientes imunossuprimidos. Relato de caso: A doença de Whipple foi diagnosticada em três homens caucasianos. Dois com histórico de dependência de álcool, um deles com cirrose hepática e outro era funcionário da drenagem de esgoto. O terceiro paciente foi que não apresentava fator de risco óbvio. Identificar fatores imunossupressores e o contato repetitivo de fezes podem ajudar no diagnóstico. Conclusão: A Doença de Whipple, por ser rara e com sintomatologia variável, necessita de suspeição médica para o diagnóstico precoce proporcionar tratamento reduzindo morbimortalidade e sequelas neurológicas.
- Published
- 2022
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46. Can the American College of Surgeons NSQIP Surgical Risk Calculator Accurately Predict Adverse Postoperative Outcomes in Emergency Abdominal Surgery? An Italian Multicenter Analysis
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Scotton, Giovanni, La Greca, Antonio, Lirusso, Chiara, Mariani, Diego, Zago, Mauro, Chiarugi, Massimo, Tartaglia, Dario, de Manzini, Nicolo, Biloslavo, Alan, Emergency Surgery Collaborative, Scotton, Giovanni, La Greca, Antonio, Lirusso, Chiara, Mariani, Diego, Zago, Mauro, Chiarugi, Massimo, Tartaglia, Dario, de Manzini, Nicolo, Biloslavo, Alan, and Emergency Surgery, Collaborative
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surgical risk calculator ,emergency surgery - Abstract
Background: The American College of Surgeons NSQIP surgical risk calculator provides an estimation of 30-day postoperative adverse outcomes. It is useful in the identification of high-risk patients needing clinical optimization and supports the informed consent process. The purpose of this study is to validate its predictive value in the Italian emergency setting. Study design: Six Italian institutions were included. Inclusion diagnoses were acute cholecystitis, appendicitis, gastrointestinal perforation or obstruction. Areas under the receiving operating characteristic curves, Brier score, Hosmer-Lemeshow index, and observed-to-expected event ratio were measured to assess both discrimination and calibration. Effect of the Surgeon Adjustment Score on calibration was then tested. A patient's personal risk ratio was obtained, and a cutoff was chosen to predict mortality with a high negative predicted value. Results: A total of 2,749 emergency procedures were considered for the analysis. The areas under the receiving operating characteristic curve were 0.932 for death (0.921 to 0.941, p < 0.0001; Brier 0.041) and 0.918 for discharge to nursing or rehabilitation facility (0.907 to 0.929, p < 0.0001; 0.070). Discrimination was also strong (area under the receiving operating characteristic curve >0.8) for renal failure, cardiac complication, pneumonia, venous thromboembolism, serious complication, and any complication. Brier score was informative (3.00 predicted the onset of death with sensitivity = 86%, specificity = 77%, and negative predicted value = 99%. Conclusions: The American College of Surgeons NSQIP surgical risk calculator has proved to be a reliable predictor of adverse postoperative outcomes also in Italian emergency settings, with particular regard to mortality. We therefore recommend the use of the surgical risk calculator in the multidisciplinary care of patients undergoing emergency abdominal surgery.
- Published
- 2023
47. Two Cases of Malingered Crime-Related Amnesia
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Stefano Zago, Alice N. Preti, Teresa Difonzo, Annalisa D'Errico, Giuseppe Sartori, Andrea Zangrossi, Nadia Bolognini, Zago, S, Preti, A, Difonzo, T, D'Errico, A, Sartori, G, Zangrossi, A, and Bolognini, N
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Human-Computer Interaction ,Memory detection ,Linguistics and Language ,Malingered crime-related amnesia ,Artificial Intelligence ,Cognitive Neuroscience ,Homicide ,Lie detection ,Experimental and Cognitive Psychology - Abstract
Amnesia is a frequent claim in major crimes, and it is estimated that the complete or partial absence of memory following a crime ranges from 25% to 50% of total cases. Although some cases may constitute a genuine form of amnesia, due to organic-neurological defects or psychological causes, and possibly combined with a dissociative or repressive coping style after an extreme experience, malingering is still fairly common in offenders. Therefore, one of the main goals in medico-legal proceedings is to find methods to determine the credibility of crime-related amnesia. At present, a number of lie and memory detection techniques can assist the forensic assessment of the reliability of declarative proof, and have been devised and improved over the past century: for example, modern polygraphs, event-related potentials, thermal imaging, functional magnetic resonance imaging, kinematic, and facial analysis. Other ad hoc psychological tests, such as the so-called Symptom Validity Test (SVT) and Performance Validity Test (PVT), as well as the autobiographical Implicit Association Test (aIAT), can also be used. To date, however, there is little evidence or case reports that document their real usefulness in forensic practice. Here, we report two cases of crime-related amnesia, whereby both defendants, who were found guilty of homicide, appeared to exhibit dissociative amnesia but where the application of SVTs, PVTs, and aIAT detected a malingered amnesia.
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- 2023
48. Implementing Enhanced Perioperative Care in Emergency General Surgery: A Prospective Multicenter Observational Study
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Ceresoli M., Biloslavo A., Bisagni P., Ciuffa C., Fortuna L., La Greca A., Tartaglia D., Zago M., Ficari F., Foti G., Braga M., Armao F. T., Bottari A., Ballabio M., Beretta L., Bondi C., Calcinati S., Carlucci M., Chiarugi M., Ciravegna A. L., Coccolini F., Cozza V., Cremonini C., Ferraina F., Fico V., Fogliata M., Germani P., Gianotti L., Grandi S., Guiotto L., Lena E., Longhi M., Lorenzi I., Malagnino A., Montino M., Paiano L., Pesenti G., Riccadonna S., Romanò B., Russo A., Somigli R., Tomajer V., Tripodi V., Ceresoli, M, Biloslavo, A, Bisagni, P, Ciuffa, C, Fortuna, L, La Greca, A, Tartaglia, D, Zago, M, Ficari, F, Foti, G, Braga, M, Armao, F, Bottari, A, Ballabio, M, Beretta, L, Bondi, C, Calcinati, S, Carlucci, M, Chiarugi, M, Ciravegna, A, Coccolini, F, Cozza, V, Cremonini, C, Ferraina, F, Fico, V, Fogliata, M, Germani, P, Gianotti, L, Grandi, S, Guiotto, L, Lena, E, Longhi, M, Lorenzi, I, Malagnino, A, Montino, M, Paiano, L, Pesenti, G, Riccadonna, S, Romanò, B, Russo, A, Somigli, R, Tomajer, V, and Tripodi, V
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emergency surgery ,era - Abstract
Introduction: ERAS pathway has been proposed as the standard of care in elective abdominal surgery. Guidelines on ERAS in emergency surgery have been recently published; however, few evidences are still available in the literature. The aim of this study was to evaluate the feasibility of an enhanced recovery protocol in a large cohort of patients undergoing emergency surgery and to identify possible factors impacting postoperative protocol compliance. Methods: This is a prospective multicenter observational study including patients who underwent major emergency general surgery for either intra-abdominal infection or intestinal obstruction. The primary endpoint of the study is the adherence to ERAS postoperative protocol. Secondary endpoints are 30-day mortality and morbidity rates, and length of hospital stay. Results: A total of 589 patients were enrolled in the study, 256 (43.5%) of them underwent intestinal resection with anastomosis. Major complications occurred in 92 (15.6%) patients and 30-day mortality was 6.3%. Median adherence occurred on postoperative day (POD) 1 for naso-gastric tube removal, on POD 2 for mobilization and urinary catheter removal, and on POD 3 for oral intake and i.v. fluid suspension. Laparoscopy was significantly associated with adherence to postoperative protocol, whereas operative fluid infusion > 12 mL/Kg/h, preoperative hyperglycemia, presence of a drain, duration of surgery and major complications showed a negative association. Conclusions: The present study supports that an enhanced recovery protocol in emergency surgery is feasible and safe. Laparoscopy was associated with an earlier recovery, whereas preoperative hyperglycemia, fluid overload, and abdominal drain were associated with a delayed recovery.
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- 2023
49. Cost-Effectiveness Analysis of Robotic-Assisted Radical Prostatectomy for Localized Prostate Cancer From the Brazilian Public System Perspective
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Miriam Allein Zago, Marcolino, Carisi Anne, Polanczyk, and Rodrigo Antonini, Ribeiro
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Health Policy ,Economics, Econometrics and Finance (miscellaneous) ,Pharmacology, Toxicology and Pharmaceutics (miscellaneous) - Published
- 2023
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50. Complicações pós-operatórias nas laringectomias totais: um estudo retrospectivo
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Namie Okino Sawada, Márcia Maria Fontão Zago, Cristina Maria Galvão, Elaine Ferreira, and Elizabeth Barichello
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General Engineering ,General Earth and Planetary Sciences ,General Environmental Science - Abstract
Trata-se de um trabalho retrospectivo para o qual foram consultados 21 prontuários de pacientes que submeteram-se à cirurgia de laringectomia total no HCFM-RP em 1996. Para a análise das complicações, dividimo-las em imediatas, mediatas e tardias. Dos 21 prontuários levantados, apenas 3 pacientes não apresentaram complicações pós-operatórias. As complicações imediatas ocorreram em cinco pacientes e as mais freqüentes foram edema (40%) e hematoma (40%); as mediatas foram detectadas em 14 pacientes, sendo do tipo deiscência de sutura e fístula (28,4%) e infecção da ferida operatória e deiscência de sutura (14,2%); com relação as complicações tardias, foram constatadas em onze pacientes e a mais frequente foi a disfagia (54,5%). Esse trabalho proporcionou-nos uma visão das complicações pós-operatórias mais freqüentes nas laringectomias totais, e este conhecimento subsidiará nossa atuação junto aos pacientes que se submeteram a essa cirurgia no que diz respeito aos cuidados perioperatórios e a sua reabilitação.
- Published
- 2022
- Full Text
- View/download PDF
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