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Primary breast lymphoma is a very rare histological entity of breast cancer. The Clinical and radiological aspects do not present any particular specificities. Diagnosis is often delayed. The treatment is mainly based on chemotherapy. We report the case of a patient with high grade malignant non-Hodgkin lymphoma. The symptomatology was made of breast swelling. The remote extension assessment was negative. The patient received 6 courses of type R mini CHOP chemotherapy followed by three-dimensional radiotherapy with a dose of 30 Gy in 15 fractions for 3 weeks.An echo mammography in between treatment showed: a partial response at 50%. Controle PET CT scan performed 3 weeks after the last cure having objectified: Complete disappearance of the active subcutaneous nodule at the level of the QSE of the right breast. Breast localisation of lymphoma is very rare. His prognosis was considerably improved due to a multidisciplinary approach. &nbsp

Paragangliomas are rare tumors arising from undifferentiated cells of the primitive neural crest. We report a case of a 33-year-old female patient who presented a large firm retroperitoneal tumor situated on the left flank above the left kidney. Levels of the serum epinephrine and norepinephrine were high. We performed a scanned biopsy; the histopathological examination and the immunohistochemical analyses concluded the diagnosis of a retroperitoneal paraganglioma. The tumor was judged secreting and inoperable; therefore it was decided to be treated with radiotherapy., Paragangliomalar, ilkel nöral krest'in farklılaşmamış hücrelerinden kaynaklanan nadir tümörlerdir. Sol böbreğin sol böbrek üzerinde yer alan geniş retroperitonal tümör hastası olan 33 yaşında bir kadın hastayı sunduk. Serum epinefrin ve norepinefrin düzeyleri yüksek bulundu. Taranmış bir biyopsi yaptık; Histopatolojik inceleme ve immunohistokimyasal analizler retroperitoneal paraganglioma tanısını koydu. Tümör salgılanıp inoperabl olarak değerlendirildi; Bu nedenle radyoterapi ile tedavi edilmeye karar verildi.

Metastatic disease to the thyroid is a very uncommon situation. The cancers that usually metastasize to the thyroid include the breast, lung, colon and kidney. To our knowledge, metastasis from the bladder to the thyroid is exceedingly rare. Here, we report a case of a unique metastatic transitional cell carcinoma to the thyroid gland three years after total cystectomy.

Aim: Endometrial cancer is the most common gynecological cancer in the West. It is the third cancer of women after that of the breast and intestine. It mainly concerns menopausal women. Our aim is to highlight, through a retrospective study and in light of literature data, the role of radiotherapy in the management of this cancer.Methods: This is a retrospective cohort study concerning patients' records for endometrial in the radiotherapy department at university hospital center of FEZ for a period of 5 years from January 2012 to December 2016.Results: We collected 158 patients of mean age 64 years (36 to 92 years), all patients had a total hysterectomy with (76% of cases) or without (24% of cases) ganglion dissection. Type 1 was the most common histological type (96% of cases). The myometrial invasion was greater than 50% in 51% of cases, histological grade III in 36% of cases, and cervical invasion was observed in 16% of cases. Therapeutically, 18% of patients received exclusive external radiotherapy at a dose of 50 Gy in conventional fractionation and spreading, a TEN at a dose of 46 Gy followed by a brachytherapy dam in 58% of cases, and 24% of patients received brachytherapy alone.After an average follow-up of 25 months, 91% of the patients are in good locoregional control, 9% of the patients had distant metastases.Conclusion: Radiotherapy retains an important place in the therapeutic strategy of high endometrial cancers, or with unfavorable histological characters, and thus allows the reduction of locoregional recurrence rates.

La cystite emphysemateuse est une forme rare d’infection urinaire basse caracterisee par la presence de gaz dans la lumiere et/ou la paroi vesicale. Le diabete represente le principal facteur de risque. Nous rapportons ici le cas d’une patiente de 51 ans hospitalisee en soins palliatifs pour la prise en charge de complications d’un adenocarcinome pancreatique (ADK) associe a un desequilibre hyperglycemique de son diabete sur fond. Le diagnostic de cystite emphysemateuse a ete retenu devant la presence de gaz dans la paroi et la lumiere vesicale sur un examen de tomodensitometrie abdomino-pelvienne realise dans le cadre d’un controle du bilan d’extension ainsi que devant la positivite de l’examen cytobacteriologique des urines qui a permis d’isoler un Escherichia coli. Le traitement a consiste en une bi-antibiotherapie a large spectre associee a un drainage vesical par sondage a demeure. Le desequilibre glycemique a ete traite par instauration d’une insulinotherapie avec arret de l’antidiabetique oral (ADO).

In this paper, we report a case of primary squamous cell carcinoma of the endometrium (PSCCE) with a literature review. A 64-year-old woman was admitted because of postmenopausal bleeding. The gynecological exam found bleeding from the endocervix. The pelvic ultrasound objectified uterine regular contours, endometrial thickened was 10 mm, the presence of an intra cavitary lesion mesuring 56/70 mm. The diagnostic hysteroscopy revealed a whitish appearance taking all the uterine cavity making evoke a tumor of the endometrium. Pelvic MRI showed a tumor limited to the uterine corpus endometrium (invasion by more than 50% of the myometrium) without invasion of the cervix. Radical hysterectomy, bilateral salpingo-oophorectomy, and lymph nodes dissection were performed. Grossly, the endometrial carcinoma was polypoid tumor occupying the entire uterine cavity. Histologically, the diagnosis of SCC was retained. No adenocarcinoma element was recognized. Neither squamous metaplasia nor dysplasia was recognized. No ectopic cervical tissue was found. The SCC was found to invade into deeper one half of the myometrium. No tumor cells were seen in other sites including the cervix, ovaries, parametres, and lymph nodes. The patients was FIGO 2009 stage IB (pT1B, N0), and was treated with adjuvant radiation. The patient had a disease progression in the pelvis 3 months after the irradiation. We reported a case of PSCCE which can help to enrich the literature for the treatment and prognosis of this disease.

The extraskeletal myxoid chondrosarcoma (CME) is a rare malignant soft tissue tumour described as a distinct clinical, histological, immunohistochemical, genetical and evolutive entity. It represents only 2.5% of soft tissue sarcomas. Its individualization is important because it has a long and indolent clinical course, and tumour-related death often occurs after a long survival period. The diagnostic key is morphological supported by immunohistochemistry and genetics t (9; 22) that allow differentiating it from other tumours with myxoid stroma and from chordoma. This report describes a patient with paravertebral extraskeletal myxoid chondrosrcoma with a high locoregional extension.