1. Association of prostate volume and prostate cancer diagnosis in patients who underwent transrectal prostate biopsy
- Author
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Ekin, Rahmi Gökhan, Yıldırım, Zübeyde, Koç, Gökhan, Diniz, Gülden, Kozacıoğlu, Zafer, and Ege Üniversitesi
- Subjects
Genel ve Dahili Tıp - Abstract
Amaç: Çalışmamızda, transrektal prostat biyopsisi yapılan hastalarda prostat hacmi ile prostat kanseri arasındaki bir ilişki olup olmadığının geriye dönük ve tek merkezli olarak araştırılması amaçlandı. Yöntem: Ocak 2014 ile Aralık 2016 arasında PSA yüksekliği veya şüpheli parmakla rektal inceleme bulgusu nedeni ilk defa prostat biyopsisi yapılan hastalar çalışmaya alındı. Çalışmada, hastaların yaşı, PSA değeri, parmakla rektal inceleme bulgusu, transrektal ultrasondaki prostat hacmi, alınan biyopsi kor sayısı, biyopsi patoloji sonucu ve Gleason skoru değerlendirildi. Bulgular: Çalışmaya 814 hasta dahil edildi. Hastaların ortalama PSA değeri 9,67±6,9 ng/ml idi ve hastaların 137’sinde (%15,6) anormal parmakla rektal inceleme bulgusu vardı. Çalışmadaki hastaların ortalama prostat hacmi 44,8±26,5 cm3 idi. Prostat hacmi 60 cm3 altı olan hasta sayısı 533 (%65,4) iken, prostat hacmi 60 cm3 üstü olan hasta sayısı 281 (%34,6) idi. Buna göre 60 cm3 altında prostat hacmi olan gruptaki hastalar istatistiksel anlamlı olarak daha gençti (61,1±9,4 vs. 67,2±8,7, p, Objective: We retrospectively investigated whether any correlation existed between prostate volume and prostate cancer in patients who underwent transrectal prostate biopsy at a single tertiary center. Methods: Patients who underwent prostate biopsy for the first time due to increased serum PSA levels and suspicious findings on digital rectal examination between January 2014 and December 2016 were included in this study . Patient’s age, serum PSA level, findings on digital rectal examination, prostate volume, number of total number of prostate biopsy cores, pathological diagnosis of prostate biopsy (cancer/benign), and Gleason score were evaluated. Results: Eight-hundred fourteen patients were included the study. Mean PSA level was 9.67±6.9 ng/ml and 137 (15.6%) of 814 patients had abnormal digital rectal examination findings. Mean prostate volume was 44.8±26.5 cm3 . Patients divided into 2 groups: 533 (65.4%) of 814 patients had a prostate volume 60 cm3 and lower, 281 (34.6%) of 814 patients had a prostate volume greater than 60 cm3 . Patients with a prostate volume 60 cm3 and lower were statistically significantly younger (61.1±9.4 vs. 67.2±8.7, p 60 cm3 (p=0.792). Conclusion: We found an association between prostate volume and prostate cancer diagnosis in patients who underwent transrectal prostate biopsy because of increased PSA levels or abnormality DRE findings Patients with a prostate volume higher than 60 cm3 had a decreased rate of prostate cancer diagnosis.
- Published
- 2018