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WOS: 000387850600033, In this present study, the ecological characteristics of Phalolepis (Cass.) DC. a section of the Centaurea L. genus growing in Turkish was investigated. Important to note is that all species of the section are restricted endemics. Physico-chemical soil analyses as well as chemical analyses of different parts of the species were conducted. Soil and bedrock samples were investigated resuling in petrographic diagnoses. Discriminant analyses were used to determine the amount of the plant nutritional elements of the different plant parts such as root, stem, and leaf, depending on physical and chemical features of 0-10 cm soil specimens. The amount of the nutrient elements in the roots, stem and leaves, the classification success percentages were 92.3, 92.3 and 88.5, respectively. The discrimination analysis success percentage of the chemical and physical soil contents resulted in 96.2%.

The aim of this study was to investigate the amount of binaural squelch effect (BSE) and head shadow effect (HSE) in children who use unilateral cochlear implants (CI) and contralateral hearing aids (HA). The study group consisted of 19 CI recipient children who consistently wore a contralateral HA. Speech sounds were used to evaluate speech perception performance in noise. Testing was performed in three listening conditions: (1) bimodal listening with noise source on HA side; (2) CI only with noise source contralaterally (HA off); (3) CI only with noise source on the CI side. Statistical analysis revealed a significant difference between the three listening conditions and post hoc tests indicated significant differences for all pairwise comparisons (p0.001). The average BSE and HSE were 11.8% and 17.1% respectively. The majority of bimodal CI users showed BSE and HSE with significant speech perception improvement in the presence of noise.Lo scopo di questo studio è stato quello di indagare il grado di effetto squelch binaurale (BSE) e di effetto ombra (HSE) nei bambini che fanno uso di impianto cocleare (CI) e protesi acustica controlaterale (HA). Sono stati arruolati 19 bambini con CI che indossavano regolarmente una HA. Per valutare la performance vocale in presenza di rumore è stato utilizzato un test di identificazione vocalica. Il test è stato eseguito in tre condizioni di ascolto: (1) ascolto bimodale con sorgente di rumore sul lato HA; (2) ascolto con CI con sorgente di rumore sul lato HA; (3) ascolto con CI con sorgente di rumore sul lato CI. I valori medi di BSE e di HSE osservati sono 11.8% e 17.1% rispettivamente. L'analisi statistica condotta ha evidenziato una differenza significativa sia nel confronto tra le tre condizioni di ascolto che per l'analisi post-hoc (p0.001). In conclusione, la maggioranza dei bambini con CI hanno mostrato BSE ed HSE con un miglioramento significativo nella percezione vocale in presenza di rumore.

OBJECTIVE: The synaptosomal-associated protein of 25 kDa (SNAP-25) gene is a presynaptic plasma membrane protein and an integral component of the vesicle docking and fusion machinery mediating secretion of neurotransmitters. Previously, several studies reported association between SNAP-25 and attention deficit hyperactivity disorder (ADHD). We investigated whether these SNAP-25 polymorphisms (MnlI T/G and DdelI T/C) were also associated with ADHD in the Turkish population. METHODS: Our study comprised unrelated 139 subjects who met DSM-IV criteria for ADHD and 73 controls and all were of Turkish origin. Genetic analyses were performed and patients were evaluated with Wender-Utah Rating Scale and Adult ADD/ADHD DSM IV-Based Diagnostic Screening and Rating Scale. RESULTS: SNAP-25 DdelI polymorphism was not associated with ADHD but there was a statistically significant difference between ADHD patients and controls for SNAP-25 MnlI polymorphism. For SNAP-25 MnlI polymorphism patients with G/G genotype of the SNAP-25 gene MnlI polymorphism had higher Wender-Utah scores and higher scores in the 1st and 3rd parts of adult ADD/ADHD Scale. CONCLUSION: We detected a significant association of the MnlI polymorphism in our ADHD sample which was similar to previous findings. Our study also revealed that SNAP-25 MnlI polymorphism was also associated with symptom severity of ADHD. This study is also, the first report on the association of SNAP-25 with ADHD in the Turkish population.

[No abstract available]

Amaç: Steroid hormonların yapımında gerekli olan enzimlerin kısmi veya tam eksiklikleri infant döneminde veya sonrasında hafif dereceden ağır derecelere kadar geniş bir semptomlar spektrumuna neden olabilmektedir. Bu yazımızda oldukça nadir görülen,kadınlarda virilizasyon ve labial füzyon gibi semptomlara neden olabilen 3 beta hidroksi steroid dehidrogenaz enzim eksikliği tespit ettiğimiz bir olguyu sunmak istedik, Objective: Partial or complete absence of enzymes which are necessary in the production of steroid hormones can cause a wide spectrum of symptoms during or after the infant from mild to severe degrees.We here present a 27-year old woman with labial fusion and virilization due to 3&bETA;-Hydroxysteroid dehydrogenase enzym defi ciency,a rare type of congenital adrenal hyperplasia

In this study, the seed germination characteristics of Salvia cyanescens a plant which is endemic for Turkey and the effects on germination rates of such factors as temperature, alkaline metal salt (NaCl, KNO3) and acid (H2SO4) concentrations and growth-regulating (GA3) substances are examined. At the end of the study, it was observed that the seed was not dormant; germination was promoted by cold-wet process at -5°C; low concentrations of NaCl and KNO3 (0.5%, 1%) brought up high germination percentage, but higher concentrations (2%>) inhibited the germination; all of the H2SO4 concentrations (0.5%-3%) inhibited the germination completely; at 1% GA3 application in different media (Jacobsen and Rodewald apparatus, Plant Growth Chamber, Room conditions) the highest germination percentage occurred in the Jacobsen apparatus and the lowest in the plant growth chamber.

Centaurea hausknetchii is a local endemic species growing only in the Nemrut Mountain Historical National Park in the Southeast Anatolian region of Turkey. It grows in three small areas of this mountain and all these areas are under heavy grazing pressure. The germination behaviour of the seeds was studied and for this purpose seeds were left under two different photoperiods (8 h light-16 h darkness and 16 h light-8 h darkness) and treated with different concentratios of NaCl, KNO3, H2SO4 and HCl solutions. There was no germination in 3 % NaCl, 1-3 % KNO3, 1-3 % H2SO4 and 2-3 % HCl concentrations in each photoperiod. According to the univariate variance analysis of germination test results, germination media with different salts, nitrate and acid concentration (e.g., 0.5 %, 1.0 %, 2.0 % NaCl; 0.5 %, 1.0 %. 2.0 %, 3.0 % KNO3; 0.5 % H2SO4; 0.5 %, 1.0 % HCl) under different photoperiods (8 h light-16 h darkness and 16 h light- 8 h darkness and 24 h light) and control have been investigated. The photoperiod and photoperiod-treatment interaction had a significant impact on the germination percentage and rate (p < 0.05). C. hausknetchii is in the critically endangered category (CR) in the IUCN 2000 Red Data Book. The habitat characteristics of the distribution sites were thus investigated, vegetative growth behaviour followed and interrelations between the increase and spread of populations recorded. The factors effecting the productivity were determined. This report will be helpful in the population biology studies and development of alternatives for effective protection programme.

OBJECTIVE: To investigate the relationship between psychosomatic disorders and surgical outcome using the Symptom Check List-90-Revised (SCL-90-R) scale. METHOD: A cross-sectional study was performed to assess the impact of preoperative psychological factors on surgical outcome by using the Symptom Check List-90-Revised scale. Sixty-one patients were evaluated preoperatively with the Symptom Check List-90-Revised scale while they verbally reported their pain at postoperative 2, 4, 6 and 24 hours. Neurological and radiological assessments were carried out at the same time. RESULTS: Symptom Check List-90-Revised scores were under 90 in 10 patients (16.5%) and over 90 in 51 patients (83.5%). Preoperative scores seemed to be highly related to sex, age and type of pathology. There was a statistically significant negative correlation between the score and the benefit from surgery (Fisher's Exact Test, p=0.007). CONCLUSION: As psychosomatic disorders are prominent in all health conditions, patient selection including psychological assessment may be a critical factor in determining functional outcomes in surgery. Patients with psychosomatic personalities may obtain less benefit from surgical intervention although surgical techniques are appropriate and postoperative clinical and radiological findings are as expected. Based on this limited sample of 61 patients, the Symptom Check List-90-Revised seems to be a useful tool in identifying additional psychological factors that may be effective on surgical outcome.

Bu çalışmada, Anadolu Karaçamı'nın [Pinus nigra Arn. subsp. pallasiana (Lamb.) Holmboe] Eskişehir'in Alpu ilçesi, Tayalar Köyü'nde ilginç bir bireyi bulunmuştur. Ayırıcı özellikleri ve bazı gözlemler belirtilmiştir., A novel individual of Anatolian Black Pine [Pinus nigra Arn. subsp. pallasiana (Lamb.) Holmboe] was found in the village of Tayalar, in the district of Alpu, province of Eskişehir province (Turkey). Distinguishing features and some observations are given.

In order to determine the heavy metal (lead, cadmium, zinc) pollution which originates from traffic in Kütahya, (Turkey) the leaves of Populus usbekistanica Kom. subsp. usbekistanica cv. "Afghanica" have been analyzed. Chemical analyses showed that the levels of Pb, Cd and Zn ranged between 0-32 mg/kg, 0.722-4.148 mg/kg, and 34.0-572.8 mg/kg dry matter, respectively.

Introduction: the COVID-19 pandemic dramatically disrupts health care around the globe. The impact of the pandemic on chronic urticaria (CU) and its management are largely unknown. Aim: to understand how CU patients are affected by the COVID-19 pandemic; how specialists alter CU patient management; and the course of CU in patients with COVID-19. Materials and methods: our cross-sectional, international, questionnaire-based, multicenter UCARE COVID-CU study assessed the impact of the pandemic on patient consultations, remote treatment, changes in medications, and clinical consequences. Results: the COVID-19 pandemic severely impairs CU patient care, with less than 50% of the weekly numbers of patients treated as compared to before the pandemic. Reduced patient referrals and clinic hours were the major reasons. Almost half of responding UCARE physicians were involved in COVID-19 patient care, which negatively impacted on the care of urticaria patients. The rate of face-to-face consultations decreased by 62%, from 90% to less than half, whereas the rate of remote consultations increased by more than 600%, from one in 10 to more than two thirds. Cyclosporine and systemic corticosteroids, but not antihistamines or omalizumab, are used less during the pandemic. CU does not affect the course of COVID-19, but COVID-19 results in CU exacerbation in one of three patients, with higher rates in patients with severe COVID-19. Conclusions: the COVID-19 pandemic brings major changes and challenges for CU patients and their physicians. The long-term consequences of these changes, especially the increased use of remote consultations, require careful evaluation., Novartis; Sanofi; Menarini Universidad Espiritu Santo; Takeda; Allakos; AstraZeneca; CSL Behring; Genentech; Pharming; GSK; Shire/Takada; BioCryst; ResTORbio; Pearl Therapeutics, CVS Health; Law offices of Levin; Riback; Adelman; Flangel; Vedder Price; Fresenius; Taiho; Kyowa Kirin; Tanabe; Korin; Uriach Pharma; Instituto Carlos III FEDER; Menarini; Amgen; Thermo Fisher; Avene; ALK‐Abello; Bencard/Allergy Therapeutics; Celgene; Allergopharma; Faes Farma; AbbVie; Janssen; Leo Pharma; Lilly; Roche; Genesis; Menlo Therapeutics; UCB; Pfizer; Almirall; Galderma; Allergika; Beiersdorf; Biocryst; Biogen Idec; BMS; Boehringer‐Ingelheim; Eli‐Lilly; Galderma; Hexal; Klosterfrau; LEO‐Pharma; LETI‐Pharma; L´Oreal; Medice; Octapharma; Pflüger; Pharming; Regeneron; Shire; ALK‐Abello; Fraunhofer‐IZI Leipzig; Hautnetz Leipzig/Westsachsen; MSD; HAL‐Allergy; Bencard; Nestle; Nutricia; Bayer Health Care; FAES; Henkel; Allakos; Argenx; Genentech Menarini; Moxie; Aralez; Celldex

WOS: 000423214200007, …, Natural History Museum, London (BM); W. Szafer Institute of Botany of the Polish Academy of Sciences; Komarov Botanical Institute of the Russian Academy of Sciences [01201255616]; Program of Basic Research of the Presidium of RAS; Scottish Government's Rural and Environment Science and Analytical Services Division; SAC, ISRO, Ahmedabad, India [GAP-3329]; Region Occitanie (Ancienne Region Midi-Pyrenees); European Union; Korea Polar Research Institute [PE17090]; RFBR [16-04-01156]; RSF [15-14-10023]; French state funds [ANR-11-IDEX-0004-02]; EU structural funding Operational Programme Research and Development for Innovation [CZ.1.05/2.1.00/19.0388]; Ministry of Education, Youth and Sports of the Czech Republic [LO1208]; MSK [00955/RRC/2015, 01211/RRC/2016]; SYNTHESYS project [GB-TAF-6565]; Institute of Botany, Jagiellonian University; Botanical Survey of India, Kolkata, This work was supported by the Natural History Museum, London (BM). The contributions by H. Bednarek-Ochyra have been financed through the statutory fund of the W. Szafer Institute of Botany of the Polish Academy of Sciences. She is also thankful to the curators at AD, AK, BM, BR, CHR, EGR, FH, H, JE, NY, PC and WELT for organising the loan of specimens. The field work of M. Lebouvier on Iles Crozet was organised within the programme 136 ECOBIO of the French Polar Institute (IPEV). E. Ginzburg thanks Dr Alexey Potemkin for various help and support. The study was carried out within the framework of the institutional research project 01201255616 of the Komarov Botanical Institute of the Russian Academy of Sciences and partly supported by the Program of Basic Research of the Presidium of RAS 'Wildlife: Current Status and Problems of Development' (subprogramme: 'Biodiversity: state and dynamics'). Neil Bell thanks David Long for facilitating the study of his uniquely valuable bryophyte collections from the Sino-Himalayan region. The Royal Botanic Garden Edinburgh is supported by the Scottish Government's Rural and Environment Science and Analytical Services Division. During 2017 we are also grateful for the support of players of People's Postcode Lottery towards our scientific research. K. K. Rawat, V. Sahu and A. K. Asthana are grateful to the Director, CSIR-NBRI for kindly providing necessary facilities. One of us (KKR) acknowledges the financial support from SAC, ISRO, Ahmedabad, India under project GAP-3329 titled 'Alpine ecosystem dynamics and impact of climate change in Indian Himalaya (PRACRITI-II). The bryophyte survey by M. Infante and C. Hannoire was part of the programme Support to the emergent Natural Reserves and Regional Natural Parks by Region Occitanie (Ancienne Region Midi-Pyrenees) with support from the European Union. Remi Lafitte (RNR Aulon) is thanked for his help during this survey, and Lars Soderstrom (Norwegian University of Science and Technology, Trondheim) kindly provided a reference specimen for identification. The work of Y.-J. Yoon and J. H. Kim was supported by the Korea Polar Research Institute (PE17090). O. M. Afonina and E. V. Kushnevskay are grateful to M. Higuchi for confirming the identification of the specimen of Hypnum callichroum from Leningrad Province. The research by O. M. Afonina was partly supported by RFBR (project no. 16-04-01156), the research of E. V. Kushnevskay by RSF (project no. 15-14-10023). The contribution of Roger Andriamiarisoa, Des Callaghan and Catherine Reeb was made under LAbex BCDIV RICCIA, supported by French state funds managed by ANR within the Investissements d'Avenir Program (reference ANR-11-IDEX-0004-02), with fieldwork authorised by The Malagasy General Directorate of Forests and Tananarivo University Department of Plant Biology (79/16/MEEMF/SG/DGF/DAPT/SCBT.re). Des Callaghan would like to thank Jiri Van. a for confirming the identification of Cylindrocolea kiaeri, Tamas Pocs for the identification of Notoscyphus lutescens and Anders Hagborg for helping to provide background literature. Catherine Reeb would like to thank Rob Gradstein for helping to confirm the identification of Jensenia spinosa and Symphyogyna podophylla.; The contributions of Vitezslav Plasek and Zuzana Skoupa were financially supported by EU structural funding Operational Programme Research and Development for Innovation, project No. CZ.1.05/2.1.00/19.0388 and by the Ministry of Education, Youth and Sports of the Czech Republic in the 'National Feasibility Program I', project LO1208 'TEWEP', MSK projects supporting Czech-Chinese cooperation, no. 00955/RRC/2015 and 01211/RRC/2016, and SYNTHESYS project GB-TAF-6565. The contribution of I. Jukoniene. was in connection with the long-term programme of the Nature Research Centre 'Research and projections into the status and change of Lithuanian nature and biological resources, scientific justification of conservation, restoration and sustainable use'. J. Eckstein, J. Nagy and P. Erzberger wish to thank Ludwig Meinunger and Wiebke Schroder, Germany, for examining the specimens of Sciuro-hypnum curtum. The contribution by Beata Cykowska-Marzencka was financially supported by the statutory fund of the W. Szafer Institute of Botany of the Polish Academy of Sciences, and the contribution by Michal Wegrzyn was financially supported by the statutory fund of the Institute of Botany, Jagiellonian University. D. K. Singh and Shuvadeep Majumdar thank the Director, Botanical Survey of India, Kolkata for facilities and financial assistance to S. M. under the 'Flora of India' project, and the authorities of State Forest Department, Govt. of Arunachal Pradesh for facilitating the field work and logistic support.