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Cluster ensemble has become an important extension to traditional clustering algorithms, yet the cluster ensemble problem is very challenging due to the inherent difficulty in resolving the label correspondence problem. We adapted the integrated K-means - Laplacian clustering approach to solve the cluster ensemble problem by exploiting both the attribute information embedded in the cluster labels and the pairwise relations among the objects. The optimal solution of the proposed approach requires computing the pseudo inverse of the normalized Laplacian matrix and the eigenvalue decomposition of a large matrix, which can be computationally burdensome for large scale document datasets. We devised an effective algebraic transformation method for efficiently carrying out the aforementioned computations and proposed an integrated K-means - Laplacian cluster ensemble approach (IKLCEA). Experimental results with benchmark document datasets demonstrate that IKLCEA outperforms other cluster ensemble techniques on most cases. In addition, IKLCEA is computationally efficient and can be readily employed in large scale document applications.

Spherical K-means algorithm (SKM) has been widely used for document clustering. Yet it is prone to getting stuck at local optimums. Recently, cluster ensemble has shown to be an effective method in improving the performance of single clustering algorithm such as SKM by combining multiple clustering solutions resulted by SKM. This paper describes and compares three graph partitioning algorithms and four hierarchy clustering algorithms for document clustering, both theoretically and empirically, using a selective cluster ensemble framework. Our experimental results over several document datasets show that, in terms of normalized mutual information, (a) The hierarchy clustering algorithms produce better clustering results than graph partitioning algorithms (b) on most datasets, the best results are arrived when the size of ensemble is between 40 and 60.

To develop a prompt and specific method for diagnosis of lung cancer. A murine monoclonal antibody against lung cancer cells was developed and characterized with the techniques of ELISA, immunohistochemistry and immunocytochemical detection of sputum. The antibody selectively bound to lung cancer tissues and exfoliated cells in the sputum from the patients with lung cancer, but did not bind to normal lung tissues and the cells in sputum either from the patients with pneumonia or from normal individuals. The antibody 2C25 has potential application for immunocytological detection of lung cancer cells in sputum.

To shorten the response time of EPCIS (Electronic Product Code Information Services) server, this paper proposes the structure of EPCIS based on proxy server and a novel cache replacement algorithm of EPCIS . A queue is built in the proxy server. The object which is more likely to be requested is moved to the head of queue, and the objects which have not been requested by now are moved to the tail of queue. The experimental results show that the new algorithm can efficiently shorten the response time of EPCIS system. Keywords-EPCIS; proxy; cache replacement algorithm

Parasitic ventricle hypothesis: a normal human heart is composed of four chambers that include two atria and two ventricles; the left ventricle is juxtaposed to the right ventricle. The left ventricle receives arterial blood from the left atrium and then ejects it into the general circulation, while the right ventricle receives venous blood from the right atrium and ejects it into the pulmonary circulation. So this structure restricts the arterial blood from mixing with the venous blood. But the heart of the patients suffering from single ventricle is composed of only one ventricle, and the patients can survive for several years, but eventually they die of hypoxemia induced by mixing up of arterial and venous blood in single ventricle. Based on these observations, we hypothesized that if an artificial akinesic ventricle device made of a biomaterial (such as pericardium autograft) (named as parasitic ventricle) is put into the single ventricle chamber of such patients, it would function as the right ventricle, and the single ventricle chamber is rendered to function as the left ventricle. Unlike the normal heart, this parasitic relationship enables to form a new type of heart structure. It has been found that the parasitic ventricle works relying on the function of the single ventricle, and the relationship of parasitism can be established between the two ventricles, "left ventricle" containing "right ventricle". This kind of heart structure can prevent the venous blood from mixing with the arterial blood; therefore, the patient in the absence of hypoxemia may survive longer. The theory is a completely new heart structure and work mode theory. We hope that this theory can open a new way to design a new operative procedure for effectively anatomically treating a patient with single ventricle. In addition, it may supply a new theory for designing a new total artificial heart with many advantages.

Few long-term results exist of mitral valve replacement (MVR) in patients with chronic mitral regurgitation (MR) and severely enlarged left ventricle. Hence, the present study was conducted to provide additional data in this respect.Between April 1988 and September 2000, 45 patients (28 males, 17 females; mean age 33.8+/-10.5 years; range: 13-58 years) with a left ventricular (LV) diastolic diameter (LVDD)70 mm underwent MVR at Anzhen Hospital. MR was rheumatic in origin in 36 patients (80%) and congenital in nine (20%). Thirteen patients were in NYHA class II, and 32 in classes III -IV. The cardiothoracic ratio was 0.64+/-0.12 (range: 0.47-0.84). The ECG showed LV hypertrophy to be present in all patients. Echocardiography showed severe MR and LV hypertrophy in all patients: LVDD was 76.3+/-4.1 mm (range: 70.2-89.6 mm). MVR was performed under hypothermic cardiopulmonary bypass.Two of 45 patients died perioperatively (mortality rate 4.4%). At two weeks after surgery, echocardiography showed a reduction in LVDD (from 76.3+/-6.5 to 65.0+/-5.2 mm) (p0.01). Follow up was completed in 37 patients (82%). Mean follow up was 4.69 years (range: 1-12.33 years). Nine patients were in NYHA class I, 21 in class II, and five in class III. Late mortality was 5%. LVDD was further decreased at late control from 76.3+/-6.5 to 60.0+/-6.1 mm (p0.001).MVR is indicated in patients with mitral insufficiency and highly dilated ventricles. In addition, perioperative mortality was acceptable and late results satisfactory. Moreover, the intervention has the potential to reduce severe LV dilation, and in some cases to revert ventricular size to normal.