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Rationale & Objective: Lumasiran reduces urinary and plasma oxalate (POx) in patients with primary hyperoxaluria type 1 (PH1) and relatively preserved kidney function. ILLUMINATE-C evaluates the efficacy, safety, pharmacokinetics, and pharmacodynamics of lumasiran in patients with PH1 and advanced kidney disease. Study Design: Phase 3, open-label, single-arm trial. Setting & Participants: Multinational study; enrolled patients with PH1 of all ages, estimated glomerular filtration rate ≤45 mL/min/1.73 m2 (if age ≥12 months) or increased serum creatinine level (if age

The main objective of the study was to investigatethe effect of different plant populations of maize and beans, at two nitrogen levels, on the performanceof the component crops.

Nitrogen supply and plant population are basic parameters for cereal-legume intercropping. In order to study plant population and nitrogen fertilizer effects on yield and yield efficiency of maizebean intercropping, a field experiment was established. Three bean plant populations and three nitrogen levels were used. Maize dry matter accumulation decreased with increases in bean plant population. Competitive effect of intercrop beans on maize yields was high at higher plant populations, being decreased by nitrogen fertilizer; application of 50 kg ha-1 N was very efficient in increasing maize cob yield. Intercropping significantly decreased harvest index of beans in all plant population and nitrogen fertilizer situations. The efficiency of intercropping, compared to sole cropping, was evidenced by the values obtained for Land Equivalent Ratio (LER) for biomass, cob and pod yields that increased with increases in bean plant populations and nitrogen fertilizer levels.

We have looked for evidence of large cross sections at large multiplicities in weakly coupled scalar field theory in three dimensions. We use spectral function sum rules to derive bounds on total cross sections where the sum can be expresed in terms of a quantity which can be measured by Monte Carlo simulation in Euclidean space. We find that high multiplicity cross sections remain small for energies and multiplicities for which large effects had been suggested., Comment: 23 pages, revtex, seven eps figures revised version: typos corrected, some rewriting of discusion, same result

We find that if the Higgs mass is close to its present experimental lower limit (100 GeV),Yukawa interactions in the quark-Higgs sector can make substantial contributions to the heavy quark MS masses., Comment: 16 pages, 1 figure. Fixed a few typos (eqs (7),(34))

We perform a Monte Carlo simulation calculation of the critical coupling constant for the continuum {\lambda \over 4} \phi^4_2 theory. The critical coupling constant we obtain is [{\lambda \over \mu^2}]_crit=10.24(3)., Comment: 11 pages, 4 figures, LaTeX

We perform a Monte Carlo simulation calculation of the critical coupling constant for the continuum {��\over 4} ��^4_2 theory. The critical coupling constant we obtain is [{��\over ��^2}]_crit=10.24(3)., 11 pages, 4 figures, LaTeX

We study electroweak parameters sensitive to the radiative corrections, such as $\rho$-ratio and $\hff$ decay rates in the $\ms$-scheme in the heavy $t$-quark mass limit $m_{t} \gg m_{w}$. In $\ms$-scheme the two-loop electroweak corrections $\sim m_{t}^{4}$ dominate over the QCD corrections $\sim \as m_{t}^{2}$ in the $\rho$-ratio. The relation between the on-shell coupling constants and $\ms$-parameters is found to be rather sensitive to the Higgs boson mass., Comment: 32 pages of Latex + 6 Postscript files of figures

We show that MS bar perturbation theory develops tachyonic singularities for some value of the dimensional regularization scale mu unless the physical Higgs mass exceeds some (cutoff dependent) minimum value., Comment: 8 pages, Latex. This submission supersedes hep-ph/9512226, hep-ph/9512286, and Phys.Lett.B377,251

We comment on different results from three recent effective potential calculations of the Higgs mass lower bound., 3 pages, LaTex

We study the scheme dependence of the two-loop expression for the $\rho$-parameter of the Standard Model in the heavy $t$-quark mass limit $m_{t} \gg m_{w}$. In the $\ms$-scheme the two-loop electroweak correction to the ${\cal O}(m_{t}^{2})$ term in $\dr$ is found greater than the QCD $\as$-correction., Comment: 9 pages (Latex) + 4 figures (Postscr.), Preprint PITT-TH-94-04

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