26 results on '"Wesley P. Gilliam"'
Search Results
2. Young Adult Pain Rehabilitation: Interdisciplinary Development and Preliminary Outcomes of a Novel Treatment Program
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Eleshia J Morrison, Michele S Tsai-Owens, Connie A Luedtke, Andrea L Eickhoff, Michele M Evans, Laurel A Oetjen, Amanda L Johannsen, Cindy J Schiebel, Kirsti K Boyum, Andrea L Reynolds, Emily R Dresher, Andrea M Ellingson, Tracy E Harrison, Daniel E Rohe, Wesley P Gilliam, Larissa L Loukianova, and Cynthia Harbeck-Weber
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Anesthesiology and Pain Medicine ,Neurology (clinical) ,General Medicine - Abstract
Background Young adults with chronic pain and symptoms experience disruptions to their social, emotional, physical, and vocational functioning. Interdisciplinary pain rehabilitation programs for pediatric and adult populations are not designed specifically to address the developmental needs of young adults. Methods This article describes the development of a novel intensive interdisciplinary outpatient rehabilitation program tailored to the unique needs of young adults with chronic pain and symptoms. Tailored content included vocational assessment and consultation, financial literacy education, and sexual health education. Results Outcome data demonstrate treatment gains, with reductions in pain interference, pain severity, pain catastrophizing, and depressive symptoms, as well as improvements in mental and physical quality of life, perceived performance, perceived satisfaction with performance, and objective measures of physical functioning. Conclusions The article concludes with clinical recommendations for the management of chronic pain and symptoms in young adults, applicable across multiple treatment settings.
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- 2022
3. Pain Catastrophizing and Pain Self-Efficacy Mediate Interdisciplinary Pain Rehabilitation Program Outcomes at Posttreatment and Follow-Up
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Jessica L Bernau, Matthew E Schumann, Jennifer R. Geske, Wesley P Gilliam, Andrea L Reynolds, Eleshia J. Morrison, Brandon J. Coombes, Mary C McDermott, and Keith E Gascho
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Self-efficacy ,Mediation (statistics) ,medicine.medical_specialty ,business.industry ,Catastrophization ,medicine.medical_treatment ,Chronic pain ,Context (language use) ,Pain rehabilitation ,General Medicine ,medicine.disease ,Self Efficacy ,Cognitive behavioral therapy ,Anesthesiology and Pain Medicine ,Quality of life ,Quality of Life ,medicine ,Physical therapy ,Humans ,Pain catastrophizing ,Neurology (clinical) ,Chronic Pain ,business ,Follow-Up Studies - Abstract
Background Decreasing pain catastrophizing and improving self-efficacy to self-manage chronic pain symptoms are important treatment targets in the context of interdisciplinary pain rehabilitation. Greater pain catastrophizing has been shown to be associated with greater impact of pain symptoms on functioning; conversely, greater pain self-efficacy has been associated with lower pain intensity and lower levels of disability. Objective To prospectively evaluate interdisciplinary pain rehabilitation outcomes, as well as to evaluate the mediating effects of both pain catastrophizing and pain self-efficacy on outcome. Methods Participants were 315 patients with chronic pain between April 2017 and April 2018 who completed a 3-week interdisciplinary pain rehabilitation program. Pain severity, pain interference, pain catastrophizing, pain self-efficacy, quality of life, depressive symptom questionnaires, and measures of physical performance were assessed before and after treatment. Follow-up questionnaires were returned by 163 participants. Effect size and reliable change analyses were conducted from pre- to posttreatment and from pretreatment to 6-month follow-up. Mediation analyses were conducted to determine the mediating effect of pain catastrophizing and pain self-efficacy on pain outcome. Results Significant improvements from pre- to posttreatment in pain outcomes were observed, and more than 80% evidenced a reliable change in at least one pain-relevant measure. Pain catastrophizing and pain self-efficacy mediated the relationship between changes in pain outcomes. Conclusions Interdisciplinary pain rehabilitation is an effective treatment, and decreasing pain catastrophizing and increasing pain self-efficacy can influence maintenance of treatment gains.
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- 2021
4. LBSAT59 Overnight Metyrapone Test And Urine Steroid Profiling In Patients Treated With Chronic Opioid Therapy: Prevalence Of Adrenal Insufficiency
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Jasmine Saini, Wesley P Gilliam, Julie L Cunningham, Karthik Thangamuthu, Lucinda M Gruber, Sumitabh Singh, Bruce Sutor, W Michael Hooten, and Irina Bancos
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Endocrinology, Diabetes and Metabolism - Abstract
Background Patients taking chronic opioids are at high risk of opioid induced adrenal insufficiency (OIAI). Previously, we showed that the prevalence of OIAI was 9% based on low morning cortisol, corticotropin (ACTH), and dehydroepiandrosterone sulfate (DHEAS). Data on the overnight metyrapone test to diagnose OIAI are sparse. We aimed to determine the prevalence of OIAI using overnight metyrapone test and identify changes in the steroid metabolome of patients treated with opioids. Methods Cross-sectional study of adult patients treated with opioid therapy of at least 20 morphine milligram equivalents (MME)/day for at least 3 months. Measurements included ACTH, cortisol, and DHEAS. Overnight metyrapone test was administered in all patients, and 24h urine steroid profiling was optional (25 steroids measured by liquid chromatography mass spectrometry1). All patients completed the quality-of-life survey (AddiQoL). Prevalence of OIAI was defined as sum of post-metyrapone 11-deoxycortisol and cortisol of Conclusion Prevalence of OIAI using overnight metyrapone test is high at 32%. Patients diagnosed with OIAI were treated with higher doses of MME/day and had a higher cumulative exposure to opioids when compared to those without OIAI. Applying 24h urine steroid profiling we showed that total glucocorticoids are 4 times lower in those with OIAI (and all Presentation: Saturday, June 11, 2022 1:00 p.m. - 3:00 p.m.
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- 2022
5. Outpatient Randomized Crossover Automated Insulin Delivery Versus Conventional Therapy with Induced Stress Challenges
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Ravinder Jeet Kaur, Sunil Deshpande, Jordan E. Pinsker, Wesley P. Gilliam, Shelly McCrady-Spitzer, Isabella Zaniletti, Donna Desjardins, Mei Mei Church, Francis J. Doyle III, Walter K. Kremers, Eyal Dassau, and Yogish C. Kudva
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Adult ,Blood Glucose ,Cross-Over Studies ,Endocrinology, Diabetes and Metabolism ,Blood Glucose Self-Monitoring ,Original Articles ,Medical Laboratory Technology ,Endocrinology ,Diabetes Mellitus, Type 1 ,Glucose ,Insulin Infusion Systems ,Insulin, Regular, Human ,Outpatients ,Humans ,Hypoglycemic Agents ,Insulin - Abstract
BACKGROUND: Automated insulin delivery (AID) systems have not been evaluated in the context of psychological and pharmacological stress in type 1 diabetes. Our objective was to determine glycemic control and insulin use with Zone Model Predictive Control (zone-MPC) AID system enhanced for states of persistent hyperglycemia versus sensor-augmented pump (SAP) during outpatient use, including in-clinic induced stress. MATERIALS AND METHODS: Randomized, crossover, 2-week trial of zone-MPC AID versus SAP in 14 adults with type 1 diabetes. In each arm, each participant was studied in-clinic with psychological stress induction (Trier Social Stress Test [TSST] and Socially Evaluated Cold Pressor Test [SECPT]), followed by pharmacological stress induction with oral hydrocortisone (total four sessions per participant). The main outcomes were 2-week continuous glucose monitor percent time in range (TIR) 70–180 mg/dL, and glucose and insulin outcomes during and overnight following stress induction. RESULTS: During psychological stress, AID decreased glycemic variability percentage by 13.4% (P = 0.009). During pharmacological stress, including the following overnight, there were no differences in glucose outcomes and total insulin between AID and physician-assisted SAP. However, with AID total user-requested insulin was lower by 6.9 U (P = 0.01) for pharmacological stress. Stress induction was validated by changes in heart rate and salivary cortisol levels. During the 2-week AID use, TIR was 74.4% (vs. SAP 63.1%, P = 0.001) and overnight TIR was 78.3% (vs. SAP 63.1%, P = 0.004). There were no adverse events. CONCLUSIONS: Zone-MPC AID can reduce glycemic variability and the need for user-requested insulin during pharmacological stress and can improve overall glycemic outcomes. Clinical Trial Identifier NCT04142229.
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- 2022
6. Treatment Effectiveness and Medication Use Reduction for Older Adults in Interdisciplinary Pain Rehabilitation
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Julie L. Cunningham, Wesley P Gilliam, Lauren Schluenz, Matthew E Schumann, and Maria I. Lapid
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medicine.medical_specialty ,PRC, Mayo Clinic Pain Rehabilitation Center ,ANCOVA, analysis of covariance ,030204 cardiovascular system & hematology ,PI, pain interference ,03 medical and health sciences ,0302 clinical medicine ,Quality of life ,IPRP, interdisciplinary pain rehabilitation program ,Medicine ,030212 general & internal medicine ,West Haven-Yale Multidimensional Pain Inventory ,Adverse effect ,ANOVA, analysis of variance ,CES-D, Center for Epidemiologic Studies- Depression Scale ,lcsh:R5-920 ,Sdiff, standard error of the difference ,business.industry ,Chronic pain ,Pain rehabilitation ,PCS, Pain Catastrophizing Scale ,Center for Epidemiologic Studies Depression Scale ,medicine.disease ,MME, morphine milligram equivalent ,PS, pain severity ,WYMHPI, West Haven-Yale Multidimensional Pain Inventory ,BZD, benzodiazepine ,OA, older adult ,QOL, quality of life ,CNP, chronic noncancer pain ,Physical therapy ,Original Article ,Pain catastrophizing ,Analysis of variance ,lcsh:Medicine (General) ,business ,PHQ-9, Patient Health Questionnaire-9 - Abstract
Objective: To examine the effectiveness of an interdisciplinary pain rehabilitation program (IPRP) that incorporates medication tapering on improving pain-related and performance-based outcomes for older adults with chronic noncancer pain and determine the proportion who demonstrated reliable improvement in outcome. Patients and Methods: This 2-year retrospective clinical cohort study examined treatment outcomes of 134 older adult patients 65 years or older with chronic noncancer pain who completed a 3-week IPRP with physician-supervised medication tapering between January 1, 2015, and December 31, 2017. Pain, pain catastrophizing, depressive symptoms, and quality of life were assessed at pretreatment, posttreatment, and follow-up. Physical performance and medication use were assessed pre- and posttreatment. Outcomes were examined using a series of repeated-measures analyses of variance, examining effect size and reliable change. Results: Significant treatment effects (P
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- 2020
7. Examining the effectiveness of pain rehabilitation on chronic pain and post-traumatic symptoms
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Julie L. Cunningham, Julia R Craner, Wesley P Gilliam, Craig N. Sawchuk, Jeannie A. Sperry, Shawna Seibel, Eleshia J. Morrison, and Matthew E Schumann
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medicine.medical_specialty ,medicine.medical_treatment ,Pain Interference ,behavioral disciplines and activities ,Stress Disorders, Post-Traumatic ,03 medical and health sciences ,0302 clinical medicine ,mental disorders ,medicine ,Humans ,Pain Management ,030212 general & internal medicine ,General Psychology ,Depressive symptoms ,Pain Measurement ,030505 public health ,business.industry ,Catastrophization ,Chronic pain ,Pain rehabilitation ,medicine.disease ,Comorbidity ,Cognitive behavioral therapy ,Psychiatry and Mental health ,Health psychology ,Physical therapy ,Pain catastrophizing ,Chronic Pain ,0305 other medical science ,business - Abstract
Patients with co-morbid chronic pain and post-traumatic stress disorder (PTSD) pose significant treatment challenges. This study evaluated the effectiveness of an interdisciplinary pain rehabilitation program (IPRP) in improving pain and PTSD outcomes, as well as reducing medication use. In addition, the mediating effect of pain catastrophizing, which is theorized to underlie the pain and PTSD comorbidity, was examined. Participants included 83 completers of an IPRP with chronic pain and a provisional PTSD diagnosis. Significant improvements were found for pain outcomes, PTSD symptomatology, depressive symptoms, physical performance, and medication use (i.e., opioids and benzodiazepines). At discharge, 86.7% of participants reliably improved in at least one key measure of functioning and 50.6% demonstrated reliable improvement in PTSD symptomatology. Change in pain catastrophizing mediated improvements in pain interference and PTSD symptomatology. Results support the potential utility of an interdisciplinary pain treatment approach in the treatment of patients with comorbid pain and PTSD.
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- 2020
8. Mediators of change in depressed mood following pain rehabilitation among participants with mild, moderate, or severe depressive symptoms
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Julia R. Craner, Matthew E. Schumann, Aex Barr, Eleshia J. Morrison, Eric S. Lake, Bruce Sutor, Lindsay G. Flegge, and Wesley P. Gilliam
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Adult ,Psychiatry and Mental health ,Clinical Psychology ,Depression ,Catastrophization ,Humans ,Pain Management ,Chronic Pain ,Self Efficacy - Abstract
Prior research indicates that depression and chronic pain commonly co-exist and impact each other. Interdisciplinary pain rehabilitation programs (IPRPs) have been shown to lead to statistically and clinically significant improvements for patients who report both depressed mood and chronic pain, however there is a gap in the literature regarding the mechanisms by which these improvements occur.This two-site, distinct sample study (Study 1: N = 303, 10-week, individual format, ACT-based program; Study 2: N = 406, 3-week, group format, CBT-based program) evaluated mediators of treatment improvement in depressive symptoms among adult IPRP participants who reported elevated depressive symptoms at program admission and examined treatment mechanisms for depressive symptoms.Self-reported pain self-efficacy and pain catastrophizing - particularly the helplessness domain - mediated the treatment-related change in depression among IPRP participants with elevated depressive symptoms across the two sites and samples. In one sample, full mediation was achieved while in the other sample, partial mediation was achieved. Participants in both samples showed improvement on all measures.This study relied on self-report measures of depressive severity and not clinical diagnosis. Results may not generalize to other populations of patients with chronic pain. There was no control condition in either study.Increasing pain self-efficacy and decreasing a sense of helplessness are important treatment targets among IPRP participants who endorse symptoms of depression.
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- 2022
9. Mental Stress and Its Effects on Vascular Health
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Jaskanwal Deep Singh Sara, Takumi Toya, Ali Ahmad, Matthew M. Clark, Wesley P. Gilliam, Lliach O. Lerman, and Amir Lerman
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Cardiovascular Diseases ,Communicable Disease Control ,COVID-19 ,Humans ,General Medicine ,Coronary Artery Disease ,Stress, Psychological - Abstract
Coronary artery disease continues to be a major cause of morbidity and mortality despite significant advances in risk stratification and management. This has prompted the search for alternative nonconventional risk factors that may provide novel therapeutic targets. Psychosocial stress, or mental stress, has emerged as an important risk factor implicated in a higher incidence of cardiovascular events, and although our understanding of this far ranging and interesting phenomenon has developed greatly over recent times, there is still much to be learned regarding how to measure mental stress and how it may impact physical health. With the current coronavirus disease 2019 global pandemic and its incumbent lockdowns and social distancing, understanding the potentially harmful biological effects of stress related to life-changing events and social isolation has become even more important. In the current review our multidisciplinary team discusses stress from a psychosocial perspective and aims to define psychological stress as rigorously as possible; discuss the pathophysiologic mechanisms by which stress may mediate cardiovascular disease, with a particular focus to its effects on vascular health; outline existing methods and approaches to quantify stress by means of a vascular biomarker; outline the mechanisms whereby psychosocial stressors may have their pathologic effects ultimately transduced to the vasculature through the neuroendocrine immunologic axis; highlight areas for improvement to refine existing approaches in clinical research when studying the consequences of psychological stress on cardiovascular health; and discuss evidence-based therapies directed at reducing the deleterious effects of mental stress including those that target endothelial dysfunction. To this end we searched PubMed and Google Scholar to identify studies evaluating the relationship between mental or psychosocial stress and cardiovascular disease with a particular focus on vascular health. Search terms included "myocardial ischemia," "coronary artery disease," "mental stress," "psychological stress," "mental∗ stress∗," "psychologic∗ stress∗," and "cardiovascular disease∗." The search was limited to studies published in English in peer-reviewed journals between 1990 and the present day. To identify potential studies not captured by our database search strategy, we also searched studies listed in the bibliography of relevant publications and reviews.
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- 2021
10. Multidisciplinary Controlled Substance Advisory Group Provides Support to the Primary Care Provider
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Julie L. Cunningham, Kimberly A. Bremseth, Sarah J. Crane, Halena M. Gazelka, Wesley P. Gilliam, Jordan D. Haag, Gabrielle J. Melin, and Benjamin Lai
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Controlled Substances ,Primary Health Care ,Humans ,General Medicine ,Practice Patterns, Physicians' - Published
- 2021
11. Prevalence of Opioid-Induced Adrenal Insufficiency in Patients Taking Chronic Opioids
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Diane Donegan, Irina Bancos, Taoran Li, Wesley P Gilliam, Julie L. Cunningham, and Larissa L. Loukianova
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Adult ,Male ,medicine.medical_specialty ,Hypothalamo-Hypophyseal System ,Hydrocortisone ,Endocrinology, Diabetes and Metabolism ,Clinical Biochemistry ,Cumulative Exposure ,Pituitary-Adrenal System ,030209 endocrinology & metabolism ,Context (language use) ,Biochemistry ,03 medical and health sciences ,Young Adult ,0302 clinical medicine ,Endocrinology ,Internal medicine ,Adrenal insufficiency ,Prevalence ,Medicine ,Humans ,In patient ,Prospective Studies ,Clinical Research Articles ,Aged ,Aged, 80 and over ,Dose-Response Relationship, Drug ,business.industry ,Dehydroepiandrosterone Sulfate ,Biochemistry (medical) ,Chronic pain ,Middle Aged ,medicine.disease ,Discontinuation ,Analgesics, Opioid ,Cross-Sectional Studies ,Opioid ,Morphine ,Female ,Chronic Pain ,business ,030217 neurology & neurosurgery ,medicine.drug ,Adrenal Insufficiency - Abstract
Context Chronic opioid use may lead to adrenal insufficiency because of central suppression of the hypothalamic-pituitary-adrenal axis. However, the prevalence of opioid-induced adrenal insufficiency (OIAI) is unclear. Objective To determine the prevalence of OIAI and to identify predictors for the development of OIAI in patients taking opioids for chronic pain. Design Cross-sectional study, 2016-2018. Setting Referral center. Patients Adult patients taking chronic opioids admitted to the Pain Rehabilitation Center. Main outcome measure Diagnosis of OIAI was considered if positive case detection (cortisol Results In 102 patients (median age, 53 years [range, 22-83], 67% women), median daily MME was 60 mg (3-840), and median opioid therapy duration was 60 months (3-360). Abnormal case detection testing was found in 11 (10.8%) patients, and diagnosis of OIAI was made in 9 (9%). Patients with OIAI were on a higher daily MME (median, 140 [20-392] mg vs 57 [3-840] mg, P = 0.1), and demonstrated a 4 times higher cumulative opioid exposure (median of 13,440 vs 3120 mg*months, P = 0.03). No patient taking 20 mg); however, specificity of MME cutoff >20 mg was only 19%. After opioid discontinuation, 6/7 patients recovered adrenal function. Conclusion The prevalence of OIAI was 9%, with MME cumulative exposure being the only predictor for OIAI development. Patients on MME of 20 mg/day and above should be monitored for OIAI.
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- 2020
12. Pain catastrophizing as a treatment process variable in cognitive behavioural therapy for adults with chronic pain
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Connie A. Luedtke, Eleshia J. Morrison, Michele M. Evans, Kevin E. Vowles, Matthew E Schumann, Wesley P Gilliam, Jeannie A. Sperry, and Julie L. Cunningham
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Adult ,Cognitive Behavioral Therapy ,business.industry ,Catastrophization ,Treatment process ,Chronic pain ,Pain Interference ,Cognition ,medicine.disease ,03 medical and health sciences ,0302 clinical medicine ,Anesthesiology and Pain Medicine ,Mood ,Treatment Outcome ,Quality of life ,Quality of Life ,Medicine ,Humans ,Pain catastrophizing ,030212 general & internal medicine ,Chronic Pain ,business ,030217 neurology & neurosurgery ,Cognitive response ,Clinical psychology - Abstract
BACKGROUND: Interdisciplinary cognitive behavioral therapy (CBT) for chronic pain is effective at improving function, mood, and pain interference among individuals with disabling chronic pain. Traditionally, CBT assumes cognitive change is an active therapeutic ingredient in the determination of treatment outcome. Pain catastrophizing, a cognitive response style that views the experience of pain as uncontrollable, permanent, and destructive, has been identified as an important maladaptive cognition which contributes to difficulties with the management of chronic pain. Consequently, pain catastrophizing is commonly targeted in CBT for chronic pain.OBJECTIVES: To examine change trajectories in pain catastrophizing during treatment and assess the relevance of these trajectories to outcomes at post-treatment.METHODS: Participants included individuals with chronic pain (N = 463) who completed a three-week program of interdisciplinary CBT. Pain catastrophizing was assessed weekly over the three weeks of treatment and latent growth curve modeling was used to identify trajectories of change.RESULTS: Findings indicated the presence of two classes of linear change, one with a significant negative slope in pain catastrophizing (i.e., improved class) and the other with a non-significant slope (i.e., unchanged class). Next, latent growth mixture modeling examined treatment outcome in relation to class membership. These results indicated that individuals in the "improved" PCS class had significantly greater improvement in pain interference and mood, as well as physical and mental quality of life compared to the "unchanged" class.CONCLUSIONS: Implications for our findings, in relation to the CBT model, are discussed.
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- 2020
13. Integrated behavioral treatment for Veterans with co-morbid chronic pain and hazardous opioid use: A randomized controlled pilot trial
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Sarah Bowen, Wesley P Gilliam, Karen J Cusack, Karlyn A. Edwards, Robert W. Bailey, Kevin E. Vowles, Katie Witkiewitz, Mindy L. McEntee, and Karen E Cardon
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Adult ,Male ,medicine.medical_specialty ,Mindfulness ,Psychological intervention ,Comorbidity ,Relapse prevention ,Acceptance and commitment therapy ,Article ,Treatment and control groups ,03 medical and health sciences ,0302 clinical medicine ,030202 anesthesiology ,Outcome Assessment, Health Care ,medicine ,Humans ,Acceptance and Commitment Therapy ,Veterans ,business.industry ,Chronic pain ,Middle Aged ,Opioid-Related Disorders ,medicine.disease ,Anesthesiology and Pain Medicine ,Neurology ,Opioid ,Physical therapy ,Feasibility Studies ,Female ,Neurology (clinical) ,Chronic Pain ,business ,Psychosocial ,030217 neurology & neurosurgery ,Follow-Up Studies ,medicine.drug - Abstract
Opioid prescription in the treatment of chronic pain is frequent and carries a risk of increased morbidity and mortality in a clinically significant number of patients, particularly those who are using opioids in a hazardous manner. Few treatment options are available that target both pain-related interference and hazardous opioid use among patients with chronic pain. In military Veterans, this issue is of particular importance as numerous reports indicate continued high rates of opioid prescription for chronic pain, as well as significant opioid-related problems. The overall aim of the present study was to determine the feasibility of an integrated psychosocial treatment in Veterans with chronic pain, who also have evidence of hazardous opioid use. To examine this aim, a random design was used to assess the feasibility and initial efficacy of integrating two empirically supported interventions: Acceptance and Commitment Therapy for chronic pain and Mindfulness Based Relapse Prevention for opioid misuse. Half of participants were randomized to the integrated treatment group and all participants received usual care (UC) through a Veteran's Administration co-occurring disorders medical clinic to treat chronic pain and opioid misuse. In total, 37 participants were randomized and included in intent to treat (ITT) analyses and 32 individuals were included in per protocol (PP) analyses with 6-month follow-up serving as the primary study endpoint. Feasibility indicators included recruitment, retention, and treatment completion rates. Recruitment fell short of targeted enrollment, although retention and completion were excellent. Primary outcome measures were opioid misuse, pain interference, and pain behavior. Simultaneous multiple regression analyses controlled for pain duration, baseline opioid dose, and baseline value for outcome measures. Results of both the ITT and PP indicated a significant effect in favor of the integrated intervention for opioid misuse, pain interference, and pain behavior. Results support the feasibility of providing an integrated treatment for both opioid risk and pain interference. PERSPECTIVE: Opioid misuse occurs in some opioid-prescribed individuals with chronic pain. Few treatment options exist that target both pain interference and opioid misuse. This study examined feasibility and initial efficacy of an integrated behavioral treatment for Veterans. Feasibility was supported, except recruitment. Efficacy was supported compared to usual care.
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- 2019
14. Unique Contributions of Acceptance and Catastrophizing on Chronic Pain Adaptation
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Wesley P Gilliam, Julia R. Craner, Afton M. Koball, Eleshia J. Morrison, and Jeannie A. Sperry
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Adult ,Male ,medicine.medical_treatment ,Affect (psychology) ,03 medical and health sciences ,0302 clinical medicine ,Psychological adaptation ,Activities of Daily Living ,Adaptation, Psychological ,medicine ,Humans ,030212 general & internal medicine ,Applied Psychology ,Pain Measurement ,Rehabilitation ,Depression ,Catastrophization ,Multilevel model ,Chronic pain ,Middle Aged ,medicine.disease ,Moderation ,Health psychology ,Cross-Sectional Studies ,Regression Analysis ,Female ,Pain catastrophizing ,Self Report ,Chronic Pain ,Psychology ,030217 neurology & neurosurgery ,Clinical psychology - Abstract
Pain catastrophizing and acceptance represent distinct but interrelated constructs that influence adaptation to chronic pain. Clinical and laboratory research suggest that higher levels of catastrophizing and lower levels of acceptance predict worse functioning; however, findings have been mixed regarding which specific outcomes are associated with each construct. The current study evaluates these constructs in relation to pain, affect, and functioning in a treatment-seeking clinical sample. Participants included 249 adult patients who were admitted to an interdisciplinary chronic pain rehabilitation program and completed measures of pain and related psychological and physical functioning. Hierarchical multiple regression analyses indicated that pain catastrophizing and acceptance both significantly, but differentially, predicted depressive symptoms and pain-related negative affect. Only pain catastrophizing was a unique predictor of perceived pain severity, whereas acceptance uniquely predicted pain interference and performance in everyday living activities. There were no significant interactions between acceptance and catastrophizing, suggesting no moderation effects. Findings from the current study indicate a pattern of results similar to prior studies in which greater levels of catastrophic thinking is associated with higher perceived pain intensity whereas greater levels of acceptance relate to better functioning in activities despite chronic pain. However, in the current study, both acceptance and catastrophizing were associated with negative affect. These relationships were significant beyond the effects of clinical and demographic variables. These results support the role of pain acceptance as an important contribution to chronic pain-related outcomes alongside the well-established role of pain catastrophizing. Results are limited by reliance on self-report data, cross-sectional design, and low racial/ethnic diversity.
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- 2017
15. The Mediating Effect of Pain Catastrophizing on PTSD Symptoms and Pain Outcome
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Matthew E Schumann, Keith E Gascho, Julia R Craner, and Wesley P Gilliam
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Adult ,Male ,medicine.medical_specialty ,Psychometrics ,Treatment outcome ,MEDLINE ,Affective distress ,behavioral disciplines and activities ,Stress Disorders, Post-Traumatic ,03 medical and health sciences ,0302 clinical medicine ,030202 anesthesiology ,mental disorders ,Medicine ,Humans ,Pain Management ,Pain Measurement ,business.industry ,Depression ,Catastrophization ,Chronic pain ,Middle Aged ,medicine.disease ,Posttraumatic stress ,Anesthesiology and Pain Medicine ,Treatment Outcome ,Stress disorders ,Physical therapy ,Pain catastrophizing ,Female ,Neurology (clinical) ,Chronic Pain ,business ,030217 neurology & neurosurgery - Abstract
Coprevalence of chronic pain and posttraumatic stress disorder (PTSD) negatively impacts the course of both disorders. Patients diagnosed with both conditions report greater pain, affective distress, and disability when compared with those with either chronic pain or PTSD alone. While the prevalence and complexity of the comorbidity is widely acknowledged, there is a dearth of research examining potential mechanism variables that might account for the relationship between chronic pain and PTSD. The current study utilizes a series of mediation analyses to examine if pain catastrophizing mediates the relationship between PTSD symptomatology and chronic pain outcome.A total of 203 treatment-seeking participants admitted to a 3-week interdisciplinary pain rehabilitation program completed a battery of psychometrically validated measures of pain severity, pain interference, pain catastrophizing, depressive symptoms, and PTSD symptoms at program admission.A series of multiple parallel mediation analyses revealed that pain catastrophizing fully mediated the relationships between PTSD symptoms and pain outcome (ie, pain severity and pain interference) above and beyond the influence of depressive symptoms.Results suggest that pain catastrophizing may represent an important cognitive mechanism through which PTSD symptoms influence the experience of chronic pain. Psychosocial treatment approaches that directly target tendency to catastrophize in response to pain may hold the potential to have salutary effects on both chronic pain and PTSD.
- Published
- 2019
16. SAT-383 Prevalence of Opioid Induced Adrenal Insufficiency in Patients Taking Chronic Opioids
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Wesley P Gilliam, Taoran Li, Irina Bancos, Diane Donegan, Larrisa Loukianova, and Julie M. Cunningham
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Cortisol Excess and Deficiency ,medicine.medical_specialty ,Cortisol awakening response ,business.industry ,Endocrinology, Diabetes and Metabolism ,Chronic pain ,medicine.disease ,Discontinuation ,chemistry.chemical_compound ,Dehydroepiandrosterone sulfate ,Opioid ,chemistry ,Internal medicine ,medicine ,Adrenal insufficiency ,Adrenal ,Prospective cohort study ,business ,Glucocorticoid ,medicine.drug - Abstract
BACKGROUND: Chronic opioid use may lead to adrenal insufficiency due to central suppression of the hypothalamic-pituitary-adrenal axis. Opioid induced adrenal insufficiency (OIAI) is likely under-recognized and its prevalence is unclear. OBJECTIVE: To determine the prevalence of OIAI in patients taking opioids for chronic pain and to identify predictors of OIAI. METHODS: A prospective study of patients admitted to the Pain Rehabilitation Center (PRC) at an academic medical center completed between 2016 and 2018. Inclusion criteria were: 1) age ≥18 years, 2) intermittent or continuous opioid use of at least 90 days, 3) am cortisol measurement on admission. Exclusion criteria were: 1) known pituitary or adrenal dysfunction, 2) exogenous glucocorticoid use within 3 months. Each patient’s opioid daily dose was converted into a morphine mg equivalent (MME). All patients had a functional 5-minute walk test and measurements of quality of life on admission to the PRC. Diagnosis of OIAI was based on the endocrine evaluation. RESULTS: One hundred sixty-two patients (median age of 53.5 years (range 21-84), 67% women, 95 % Caucasian) met inclusion criteria. Patients used opioids daily (141, 87%) or as needed (21, 13.0%) at a median MME of 30 mg (3-840), median duration of 60 months (3-360). In addition to morning cortisol (CORT), 112 (69.1%) patients had measurements of corticotropin (ACTH) and 106 (65.4%) - dehydroepiandrosterone sulfate (DHEAS). CORT was directly correlated with both DHEAS (p=0.04) and ACTH (p20 mg), however specificity of MME cutoff >20 mg to predict OIAI development was only 34%. After opioid discontinuation, 3/8 patients recovered adrenal function when reassessed at 14 months (5-14). CONCLUSION: The prevalence of OIAI based on the endocrine evaluation was 5%, with MME being the only predictor for OIAI development. Patients on MMED of 20 mg and above should be monitored for OIAI. Abnormalities in the hypothalamic-pituitary-adrenal axis were frequent, affecting 14-21% of patients taking opioids, possibly contributing to patients’ symptoms, physical performance and well-being.
- Published
- 2019
17. Patients’ perceptions of a chronic pain rehabilitation program: changing the conversation
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Julia R. Craner, Wesley P Gilliam, Jeannie A. Sperry, Rosei R Skipper, and Eleshia J. Morrison
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Adult ,Male ,Biopsychosocial model ,Health Knowledge, Attitudes, Practice ,medicine.medical_specialty ,medicine.medical_treatment ,Alternative medicine ,Young Adult ,03 medical and health sciences ,0302 clinical medicine ,Patient satisfaction ,Cultural diversity ,medicine ,Humans ,Pain Management ,Behavior management ,030212 general & internal medicine ,Physical Therapy Modalities ,Aged ,Pain Measurement ,Aged, 80 and over ,Rehabilitation ,business.industry ,Communication ,Chronic pain ,General Medicine ,Middle Aged ,Patient Acceptance of Health Care ,medicine.disease ,Moderation ,Treatment Outcome ,Physical therapy ,Female ,Perception ,Self Report ,Chronic Pain ,business ,030217 neurology & neurosurgery - Abstract
Objective Research supports the effectiveness of comprehensive approaches to chronic pain treatment, including behavioral management and physical reconditioning. However, less is known about patients' perceptions of this treatment approach. The current study evaluated patient perceptions and treatment outcomes utilizing both qualitative and quantitative data collection. Methods A total of 498 adult patients (≥18 years of age; Mage = 49.1) completed an intensive outpatient interdisciplinary chronic pain rehabilitation program, completed survey measures at admission and discharge, and were asked open-ended questions about their treatment experience at discharge. Results Patients reported significant decreases in pain severity, t(488) = 23.08, p
- Published
- 2016
18. 0666 RLS/WED In The Setting Of Opioid Withdrawal
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Wesley P Gilliam, Melissa C. Lipford, Joshua R. Labott, Larissa L. Loukianova, Jeannie A. Sperry, Judy K Gebhard, and Julie L. Cunningham
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Opioid withdrawal ,business.industry ,Physiology (medical) ,Anesthesia ,Medicine ,Neurology (clinical) ,business - Published
- 2019
19. Longitudinal Treatment Outcomes for an Interdisciplinary Pain Rehabilitation Program: Comparisons of Subjective and Objective Outcomes on the Basis of Opioid Use Status
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Jeannie A. Sperry, Connie A. Luedtke, Eleshia J. Morrison, Wesley P Gilliam, Michele M. Evans, Julie L. Cunningham, Julia R Craner, and Larissa L. Loukianova
- Subjects
Adult ,Male ,medicine.medical_specialty ,Treatment outcome ,03 medical and health sciences ,0302 clinical medicine ,medicine ,Humans ,Pain Management ,030212 general & internal medicine ,Medical prescription ,Aged ,Cognitive Behavioral Therapy ,business.industry ,Opioid use ,Public health ,Chronic pain ,Opioid use disorder ,Pain rehabilitation ,Middle Aged ,medicine.disease ,Exercise Therapy ,Analgesics, Opioid ,Anesthesiology and Pain Medicine ,Treatment Outcome ,Neurology ,Opioid ,Physical therapy ,Female ,Neurology (clinical) ,Chronic Pain ,business ,030217 neurology & neurosurgery ,medicine.drug - Abstract
Chronic pain is a major public health concern, and widespread use of prescription opioids for chronic pain has contributed to the escalating problem of opioid use disorder. Interdisciplinary pain rehabilitation programs (IPRPs) can be highly effective in discontinuing opioids in patients with chronic pain while also improving functional status. This study sought to examine self-report and performance-based functional outcomes of 2 cohorts of patients enrolled in a 3-week IPRP: patients engaged in interdisciplinary pain treatment and physician-supervised opioid taper versus nonopioid users engaged in interdisciplinary treatment. Immediate and long-term treatment outcomes were assessed using a series of 2 (group: opioid use, no opioid use) × 2 (period: pretreatment, post-treatment) and 2 (group: opioid use, no opioid use) × 2 (period: pretreatment, 6 months post-treatment) mixed model analyses of variance. Group × Period interactions were nonsignificant whereas period effects were significant for all outcomes in directions indicating improvement (Ps .001) at discharge from the program and at 6 months, irrespective of opioid use status. Results support the assertion that IPRPs lead to significant improvements in subjective as well as objective indices of function, irrespective of opioid use status. Implications for our findings are discussed.This article provides support for the effectiveness of interdisciplinary, rehabilitative models of care in improving physical and emotional functioning of patients with chronic pain while simultaneously discontinuing opioid use. The reach of this work is substantial, because opioid dependency and chronic pain are public health problems in the United States.
- Published
- 2017
20. Hearing New Voices: Registered Nurses and Health Technicians Experience Caring for Chronic Pain Patients in Primary Care Clinics
- Author
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Linda Honan Pellico, Wesley P Gilliam, Robert D. Kerns, and Allison Lee
- Subjects
medicine.medical_specialty ,High prevalence ,content analysis ,business.industry ,Chronic pain ,Krippendorff method ,Primary care ,medicine.disease ,Primary care clinic ,Article ,Nursing ,Ambulatory care ,Content analysis ,Family medicine ,medicine ,Global health ,primary care clinic ,business ,General Nursing ,Primary nursing - Abstract
Recent national estimates from the U.S. reveal that as many as one-third of all Americans experience chronic pain resulting in high prevalence rates of visits to primary care clinics (PCC). Indeed, chronic pain appears to be an emerging global health problem. Research has largely ignored the perspective of PCC staff other than physicians in providing care for patients with chronic pain. We wanted to gain insights from the experiences of Registered Nurses (RNs) and Health Technicians (HTs) who care for this patient population. Krippendorff’s method for content analysis was used to analyze comments written in an open-ended survey from fifty-seven primary care clinic staff (RNs-N=27 and HTs-N=30) respondents. This represented an overall response rate of 75%. Five themes emerged related to the experience of RNs and HTs caring for patients with chronic pain: 1) Primacy of Medications and Accompanying Clinical Quandaries; 2) System Barriers; 3) Dealing with Failure; 4) Primacy of Patient Centered Care; and 5) Importance of Team Based Care. This study demonstrates that nursing staff provide patient-centered care, recognize the importance of their role within an interdisciplinary team and can offer valuable insight about the care of patients with chronic pain. This study provides insight into strategies that can mitigate barriers to chronic pain management while sustaining those aspects that RNs and HTs view as essential for improving patient care for this vulnerable population in PCCs.
- Published
- 2014
21. The Mediating Effects of the Different Dimensions of Pain Catastrophizing on Outcomes in an Interdisciplinary Pain Rehabilitation Program
- Author
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Julia R. Craner, Jeannie A. Sperry, Eleshia J. Morrison, and Wesley P Gilliam
- Subjects
Male ,medicine.medical_specialty ,Psychometrics ,Catastrophization ,Pain ,03 medical and health sciences ,0302 clinical medicine ,Quality of life (healthcare) ,030202 anesthesiology ,medicine ,Humans ,In patient ,Depression (differential diagnoses) ,Pain Measurement ,Psychiatric Status Rating Scales ,business.industry ,Depression ,Pain rehabilitation ,Middle Aged ,Anesthesiology and Pain Medicine ,Treatment Outcome ,Psychiatric status rating scales ,Physical therapy ,Quality of Life ,Pain catastrophizing ,Female ,Neurology (clinical) ,business ,030217 neurology & neurosurgery - Abstract
Although reducing pain catastrophizing has been shown to contribute to functional improvement in patients receiving interdisciplinary pain care, little is known about how changes in the different dimensions of pain catastrophizing uniquely contribute to improvement in outcome. The study examined the unique relationship between changes in the 3 distinct factors of pain catastrophizing-helplessness, rumination, and magnification-and changes in pain outcomes.In this nonrandomized study, 641 patients who completed treatment in a 3-week interdisciplinary pain rehabilitation program between the years 2013 and 2014 completed a battery of psychometrically validated measures of pain catastrophizing, pain severity, pain interference, mental and physical health-related quality of life, and depressive symptoms at pretreatment and posttreatment.A series of within groups (repeated measures) mediation analyses were conducted. Change in the helplessness, rumination, and magnification subscales were entered as multiple mediators in the model. Analyses revealed that change in helplessness partially mediated improvement in all outcome variables beyond the influence of change in other variables in the model, whereas change in rumination partially mediated improvement in pain severity, interference, and depressive symptoms. Change in magnification had the least impact on outcome, partially mediating improvements in only mental health quality of life.Results suggest that changes in the 3 dimensions of pain catastrophizing differentially mediate improvement in pain outcome. Treatment approaches that specifically target helplessness and rumination may be particularly useful in improving the outcomes of patients with refractory pain conditions enrolled in interdisciplinary pain rehabilitation program.
- Published
- 2016
22. Rumination, Magnification, and Helplessness: How do Different Aspects of Pain Catastrophizing Relate to Pain Severity and Functioning?
- Author
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Wesley P Gilliam, Julia R. Craner, and Jeannie A. Sperry
- Subjects
Male ,Learned helplessness ,03 medical and health sciences ,0302 clinical medicine ,030202 anesthesiology ,medicine ,Humans ,Differential impact ,Pain Measurement ,Psychiatric Status Rating Scales ,business.industry ,Depression ,Catastrophization ,Chronic pain ,Middle Aged ,medicine.disease ,Analgesics, Opioid ,Anesthesiology and Pain Medicine ,Pain severity ,Rumination ,Quality of Life ,Regression Analysis ,Pain catastrophizing ,Female ,Neurology (clinical) ,medicine.symptom ,Chronic Pain ,business ,030217 neurology & neurosurgery ,Clinical psychology - Abstract
Although there is a large body of research on the relationship between pain catastrophizing and functioning among individuals with chronic pain, little is known about the potential differential impact of specific aspects of pain catastrophizing. The current study evaluates the relationship between the Rumination, Helplessness, and Magnification subscales of the Pain Catastrophizing Scale and pain-related outcomes.In total, 844 patients who were admitted to a chronic pain rehabilitation program completed survey measures of pain, catastrophizing, quality of life (QOL), and depression.A series of analyses were conducted entering the 3 subscales simultaneously in a predictive model after pain intensity and demographic variables (ie, age, sex, pain duration, current opioid use). The Helplessness subscale accounted for unique variance in the prediction of pain severity, pain-related interference, mental and physical health-related QOL, and depressed mood. Magnification was significantly related to physical and mental health-related QOL and depressed mood. The Rumination subscale was not uniquely associated with any of the outcome measures beyond that which was accounted for by pain severity, magnification, or helplessness.Pain catastrophizing is a multifaceted construct, and different domains of catastrophizing are uniquely related to pain-related outcomes. This study represents the first to evaluate the functioning of these subscales in a large, diagnostically heterogeneous sample of chronic pain patients.
- Published
- 2016
23. Young adults with chronic pain: outcomes of a pilot program to meet development needs
- Author
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Eleshia J. Morrison, D. Luedtke, Michele M. Evans, Wesley P Gilliam, Jeannie A. Sperry, and Connie A. Luedtke
- Subjects
medicine.medical_specialty ,Anesthesiology and Pain Medicine ,Neurology ,business.industry ,Chronic pain ,medicine ,Physical therapy ,Pilot program ,Neurology (clinical) ,Young adult ,medicine.disease ,business - Published
- 2018
24. Stepped care model of pain management and quality of pain care in long-term opioid therapy
- Author
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Christopher B. Ruser, Wesley P Gilliam, Robert D. Kerns, Brent A. Moore, Daren Anderson, Ianita Zlateva, Allison Lee, Lindsey M. Dorflinger, Khushbu Khatri, and Terrence Tian
- Subjects
Male ,medicine.medical_specialty ,Time Factors ,Referral ,Pain medicine ,Population ,03 medical and health sciences ,0302 clinical medicine ,Pain assessment ,medicine ,Outpatient clinic ,Humans ,Pain Management ,030212 general & internal medicine ,education ,Veterans Affairs ,Aged ,Pain Measurement ,Quality of Health Care ,Veterans ,education.field_of_study ,business.industry ,Rehabilitation ,Chronic pain ,Reproducibility of Results ,medicine.disease ,Quality Improvement ,United States ,Analgesics, Opioid ,Family medicine ,Physical therapy ,Female ,Chronic Pain ,business ,030217 neurology & neurosurgery ,Patient education ,Follow-Up Studies - Abstract
INTRODUCTION Chronic pain poses a substantial burden on the health of the U.S. population. Estimates suggest that over 100 million Americans experience persistent pain [1-2], with higher prevalence among Veterans [3] as well as medically underserved populations [4]. Among Veterans treated at Veterans Health Administration (VHA) primary care clinics, 50 percent report persistent pain [3,5]. A recent study in a large Federally qualified health center (FQHC) found that 40 percent of all adult ambulatory visits involved patients with chronic pain [6]. In addition, costs are estimated to exceed $600 billion in medical expenses and lost productivity [7]. Although specialized multidisciplinary pain treatment is necessary and effective, particularly for more complex patients [8-9], access to these services is limited and is often not needed [7,10]. Thus, while most patients with chronic pain are treated by a primary care provider (PCP), most PCPs face organizational and administrative barriers to providing effective care [11], receive limited training in pain management [12-13], express low confidence in their ability to care for such patients [14-17], and hold reservations regarding treatment of chronic pain. Studies suggest that there is wide variability in PCPs' adherence to guidelines for pain management [18-20], and documentation of comprehensive pain care plans and specific treatment provided is poor [21-22]. Effective models of pain management in primary care have been developed. The most widely promoted evidence-based model is the Stepped Care Model for Pain Management (SCM-PM). The model, advocated by the American Academy of Pain Medicine [23], is the basis for the VHA's national pain management strategy [24-29]. It emphasizes an individualized, stepwise approach to pain management as patients increase in complexity and/or fail to achieve treatment goals with more conservative interventions [30]. Although several studies have demonstrated the potential for quality improvement initiatives to increase the quality of pain management, such initiatives are limited by a lack of well-established quality measures and benchmarks to measure their effect [6,22,30-32]. Recently, our group developed and validated a new tool for extracting information from electronic health records (EHRs) on the quality of documentation of pain and pain management [33]. Three dimensions of pain care quality were targeted, namely pain assessment (e.g., assessment of functioning and pain interference), treatment plans (e.g., patient education), and pain reassessment (i.e., assessment of outcomes). The current study was designed to further examine the psychometric properties of the measure with a specific focus on examining its responsivity to change in the context of a 5 yr performance improvement project designed to promote implementation of the SCM-PM with a specific focus on improved management of patients receiving long-term opioid therapy. Here we examine outcomes in one multisite VHA healthcare system, with replication and crossvalidation of the utility of this measurement approach in another multisite FQHC that was conducting a similar SCM-PM-based quality improvement initiative. METHODS Setting and Intervention Department of Veterans Affairs Connecticut Healthcare System The Department of Veterans Affairs Connecticut Healthcare System (VACHS) is composed of two academically affiliated VHA medical centers and six community-based outpatient clinics. About 50,000 Veterans receive care within VACHS annually. In addition to primary care services provided by an interdisciplinary team consistent with VHA's Patient Aligned Care Team model of care [34], VACHS PCPs and patients have access to a range of specialty pain management services, including rehabilitation, mental health, pain medicine, and complementary and integrative approaches. Project Step was a 5 yr study designed to examine the adoption and implementation of SCM-PM throughout VACHS, with a particular emphasis on improvements to pain management in the primary care setting and appropriate referral to secondary specialty care [28]. …
- Published
- 2014
25. Development and application of an electronic health record information extraction tool to assess quality of pain management in primary care
- Author
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Robert D. Kerns, Allison Lee, Wesley P Gilliam, and Lindsey M. Dorflinger
- Subjects
medicine.medical_specialty ,business.industry ,Public health ,Chronic pain ,Alternative medicine ,Primary care ,computer.software_genre ,medicine.disease ,Behavioral Neuroscience ,Information extraction ,Health psychology ,Inter-rater reliability ,Documentation ,Family medicine ,medicine ,Medical emergency ,business ,computer ,Applied Psychology ,Original Research - Abstract
Chronic pain is one of the most common presenting problems in primary care. Standards and guidelines have been developed for managing chronic pain, but it is unclear whether primary care providers routinely engage in guideline-concordant care. The purpose of this study is to develop a tool for extracting information about the quality of pain care in the primary care setting. Quality indicators were developed through review of the literature, input from an interdisciplinary panel of pain experts, and pilot testing. A comprehensive coding manual was developed, and inter-rater reliability was established. The final tool consists of 12 dichotomously scored indicators assessing quality and documentation of pain care in three domains: assessment, treatment, and reassessment. Presence of indicators varied widely. The tool is reliable and can be utilized to gather valuable information about pain management in the primary care setting.
- Published
- 2014
26. Persistent pain and comorbidity among Operation Enduring Freedom/Operation Iraqi Freedom/operation New Dawn veterans
- Author
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Wesley P Gilliam, Sally G. Haskell, Diana M. Higgins, Joseph L. Goulet, Cynthia Brandt, Harini Bathulapalli, and Robert D. Kerns
- Subjects
Adult ,Male ,medicine.medical_specialty ,Substance-Related Disorders ,Comorbidity ,Stress Disorders, Post-Traumatic ,medicine ,Prevalence ,Humans ,Longitudinal Studies ,Obesity ,Psychiatry ,Iraq War, 2003-2011 ,health care economics and organizations ,Veterans ,Depressive Disorder ,Afghan Campaign 2001 ,business.industry ,Chronic pain ,General Medicine ,Middle Aged ,medicine.disease ,Mental health ,United States ,Substance abuse ,United States Department of Veterans Affairs ,Anesthesiology and Pain Medicine ,Pain Clinics ,Logistic Models ,Mood disorders ,Multivariate Analysis ,Physical therapy ,Anxiety ,Pain catastrophizing ,Female ,Neurology (clinical) ,medicine.symptom ,Chronic Pain ,business - Abstract
Objective Chronic pain is a significant concern for the Veterans Health Administration (VHA), with chronic pain conditions among those most frequently reported by Operation Enduring Freedom (OEF)/Operation Iraqi Freedom (OIF)/Operation New Dawn (OND) veterans. The current study examined VHA electronic medical record data to examine variation in demographics and high prevalence and high impact medical and mental health conditions in order to characterize the differences between patients with persistent pain and no pain. Design A conservative operational definition of chronic or “persistent pain” based on multiple indicators of pain (i.e., pain intensity ratings, prescription opioids, pain clinic visits, International Classification of Diseases, Ninth Revision codes) was employed. Analyses included the entire roster of longitudinal clinical data on OEF/OIF/OND veterans who used VHA care to compare those with persistent pain with those with no clinical evidence of pain. Results Results of logistic regression models suggest that sex, race, education, military variables, body mass index (BMI), traumatic brain injury (TBI), and mental health conditions, but not age, reliably discriminate the two groups. Those with persistent pain were more likely to be Black, female, on active duty, enlisted, Army service members, have a high school education or less, and have diagnoses of mood disorders, post-traumatic stress disorder, substance use disorders, anxiety disorders, TBI, and have a BMI consistent with overweight and obesity. Conclusions The operational definition of chronic pain used in this study may have research implications for examining predictors of incident and chronic pain. These data have important clinical implications in that addressing comorbid conditions of persistent pain may improve adaptive coping and functioning in these patients.
- Published
- 2014
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