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Background: Corona virusis identified since 2002 and from seven strain severe acute respiratory syndrome corona virus and middle east respiratory syndrome corona virus causes severity in patients and then in December 2019, an outbreak of severe acute respiratory syndrome Corona virus 2 infection ensued in Wuhan, China and spread crosswise China and beyond. On February 12, 2020, WHO officially named the disease caused by the novel Corona virusas Corona virus Disease 2019 (COVID-19). Main Text: This form of virus comes up its growth when expose to any of the naturally expose material and the precaution for this is only single oriented, that is keeping yourself hygienic by washing your hands by utilizing high grade sanitizer. The literature survey revealed that Corona virus strain mainly severe acute respiratory syndrome corona virus and middle east respiratory syndrome Corona virus and human corona virus preserve on various surfaces like metal, glass or plastic for about 9 days but inactivation of virus by utilizing various virucide. On infection, the virus has a surge of proinflammatory cytokines and chemokines, which do damage to lung tissue, deterioration of lung function, and then eventually go to lung failure. Drug discovery against the virus is a challenging line of work owing to frequent recombination events. The evolution of a vaccine is another significant facet. Research is in ongoing stage to develop vaccine and medicines for COVID 19. In such circumstances, other system of medicineis widely used, like Allopathy, Ayurveda and Unani. Unani system of medicine utilized some measures for health protection during epidemics. In Unani medicine, during an epidemic, apart from isolation and quarantine, three measures are of utmost importance, impurification of surroundings using certain herbal drugs as fumigants or sprays, health promotion and immune-modulation, and use of health-protecting drugs and symptom-specific drugs. Conclusion: We require more structural biological details which put up rush up the drug or vaccine development process against corona virus. Thus, objective of this follow-up article is to focus on past to present perspective on corona virus pandemic.

Bioinformatics is a noteworthy in appreciative the composite mechanisms of the cell and it is very beneficial for biomedical investigators to examination the clinical samples. Bioinformatics includes the usage of methods comprising useful mathematics, computer science, informatics, artificial intelligence (AI), statistics, chemistry, and biochemistry to resolve biological difficulties frequently on the molecular level. Bioinformatics tools provide significant benefits for nutrition discovery agendas such as cost-saving, time-to-market, and in-sight. The practical feature of bioinformatics is to recognize the code of life that is to decode the evidence that exists in the nucleotide sequence. Chemo-informatics is the application of computer and informational methods to challenge chemical problems, which highlight the manipulation of chemical structural information. Bioinformatics having numerous applications such as molecular medicine, personalized medicine, preventive medicine, gene therapy, etc. Several software packages are significant and free, and secure by well-known organizations. These consist of databanks like ChEMBL and SwissSidechain, software tools like 3D visualization, UCSF Chimera, and provides platform for software designers fascinated in structural biology, SwissSimilarity for virtual screening, Swiss-Bioisostere for ligand design, SwissTarget.