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1. The development of the literary-artistic language through student's creativity-stimulating methods

Author

Vico, l Nelu, Antip, Crina Ramona, and Dănăilă-Moisă, Mihaela

Subjects
language, student, communication, ComputingMilieux_COMPUTERSANDEDUCATION, active-participative methods, creativity
Abstract

Creativity and language are topical terms in the instructional and educational approach of the students, therefore it is important for the teacher to aim to develop these two components constantly and continuously, mostly in the context of institutionalized education, using active-participatory methods that support his or hers teaching activities.

Published
2020
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2. Involvement of phospholipase D in mineralization process in cultured osteoblasts

Author

Abdallah, D., Skafi, N., Hamade, E., Reibel, S., Vitale, N., El Jamal, A., Bougault, C., Laroche, B., Vico, L., Badran, B., Hussein, N., Magne, D., Buchet, R., Brizuela, L, Mebarek, S., ICBMS, UMR5246, Métabolisme, Enzymes et Mécanismes Moléculaires (MEM²), Institut de Chimie et Biochimie Moléculaires et Supramoléculaires (ICBMS), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National des Sciences Appliquées de Lyon (INSA Lyon), Université de Lyon-Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Institut de Chimie du CNRS (INC)-École Supérieure Chimie Physique Électronique de Lyon-Centre National de la Recherche Scientifique (CNRS)-Université Claude Bernard Lyon 1 (UCBL), and Université de Lyon-Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Institut de Chimie du CNRS (INC)-École Supérieure Chimie Physique Électronique de Lyon-Centre National de la Recherche Scientifique (CNRS)

Subjects
[SDV.BBM.BC]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Biochemistry [q-bio.BM], [SDV.BBM.BC] Life Sciences [q-bio]/Biochemistry, Molecular Biology/Biochemistry [q-bio.BM], ComputingMilieux_MISCELLANEOUS
Abstract

International audience

Published
2019

3. 3D Analysis of Cortical and Trabecular Bone From Hip DXA: Precision and Trend Assessment Interval in Postmenopausal Women

Author

Humbert, L, Winzenrieth, R, Di Gregorio, S, Thomas, T, Vico, L, Malouf, J, and Barquero, LMD

Subjects
musculoskeletal diseases, cortex, trabecular bone, trend assessment intervals, precision, 3D modeling
Abstract

The 3D distribution of the cortical and trabecular bone mass is a critical component in determining the resistance of a bone to fracture that is not assessed in standard dual-energy X-ray absorptiometry (DXA) exams. In this work, we assessed in vivo short-term precision of measurements provided by 3D modeling techniques from DXA scans and trend assessment intervals (TAIs) in postmenopausal women. Subjects included to study precision errors were scanned twice, with repositioning for duplicate hip scans, using either a Lunar iDXA scanner (GE Healthcare, Madison, WI) or a Discovery W scanner (Hologic, Inc., Waltham, MA). Postmenopausal women having baseline and 18-mo follow-up visit were scanned using a Lunar iDXA device to assess TAIs. TAIs indicate what time intervals are required to allow accurate assessment of response to treatment or progression of disease. The 3D-SHAPER software (Galgo Medical, Barcelona, Spain) was used to derive 3D measurements from hip DXA scans. Least significant changes were 10.39 and 8.72 mg/cm(3) for integral volumetric bone mineral density (BMD), 9.64 and 9.59 mg/cm(3) for trabecular volumetric BMD, and 6.25 and 5.99 mg/cm(2) for cortical surface BMD, using the Lunar iDXA and Discovery W scanners, respectively. TAIs in postmenopausal women were 2.9 yr (integral volumetric BMD), 2.6 yr (trabecular volumetric BMD), and 3.5 yr (cortical surface BMD), using the Lunar iDXA scanner. As a comparison, TAIs for areal BMD were 2.8 yr at neck and 2.7 yr at total femur. Least significant changes of measurements provided by 3D modeling techniques from DXA were assessed. TAIs in postmenopausal women were similar to those measured for areal BMD measurements. DXA-derived 3D measurements could potentially provide additional indicators to improve patient monitoring in clinical practices.

Published
2019

4. Cortical and Trabecular Bone Microstructure Did Not Recover at Weight-Bearing Skeletal Sites and Progressively Deteriorated at Non-Weight-Bearing Sites During the Year Following International Space Station Missions

Author

Vico, L., van Rietbergen, B., Vilayphiou, N., Linossier, M.T., Locrelle, H., Normand, M., Zouch, M., Gerbaix, M., Bonnet, N., Novikov, V., Thomas, T., Vassilieva, G., and Orthopaedic Biomechanics

Subjects
Adult, ddc:616, BONE HR-pQCT, Radius/anatomy & histology, Walking, Middle Aged, Space Flight, BONE RECOVERY, MICROGRAVITY, Biomechanical Phenomena, Tibia/anatomy & histology, Cortical Bone/anatomy & histology, Weight-Bearing, SDG 3 - Good Health and Well-being, Cancellous Bone/anatomy & histology, PERIOSTIN, Humans, Bone Density/physiology, Tomography, X-Ray Computed, SPACEFLIGHT, Biomarkers/blood
Abstract

Risk for premature osteoporosis is a major health concern in astronauts and cosmonauts; the reversibility of the bone lost at the weight-bearing bone sites is not established, although it is suspected to take longer than the mission length. The bone three-dimensional structure and strength that could be uniquely affected by weightlessness is currently unknown. Our objective is to evaluate bone mass, microarchitecture, and strength of weight-bearing and non-weight-bearing bone in 13 cosmonauts before and for 12 months after a 4-month to 6-month sojourn in the International Space Station (ISS). Standard and advanced evaluations of trabecular and cortical parameters were performed using high-resolution peripheral quantitative computed tomography. In particular, cortical analyses involved determination of the largest common volume of each successive individual scan to improve the precision of cortical porosity and density measurements. Bone resorption and formation serum markers, and markers reflecting osteocyte activity or periosteal metabolism (sclerostin, periostin) were evaluated. At the tibia, in addition to decreased bone mineral densities at cortical and trabecular compartments, a 4% decrease in cortical thickness and a 15% increase in cortical porosity were observed at landing. Cortical size and density subsequently recovered and serum periostin changes were associated with cortical recovery during the year after landing. However, tibial cortical porosity or trabecular bone failed to recover, resulting in compromised strength. The radius, preserved at landing, unexpectedly developed postflight fragility, from 3 months post-landing onward, particularly in its cortical structure. Remodeling markers, uncoupled in favor of bone resorption at landing, returned to preflight values within 6 months, then declined farther to lower than preflight values. Our findings highlight the need for specific protective measures not only during, but also after spaceflight, because of continuing uncertainties regarding skeletal recovery long after landing.

Published
2017

5. Oxidative imbalance in low/intermediate-1-risk myelodysplastic syndrome patients: The influence of iron overload

Author

Ivars D, Orero MT, Javier K, Díaz-Vico L, García-Giménez JL, Mena S, Tormos C, Egea M, Pérez PL, Arrizabalaga B, Ruiz MÁ, Yagüe N, Tormo M, Sancho-Tello R, Gomes A, Algueró C, O'Connor JE, Sáez GT, Carbonell F, and Collado R

Subjects
Oxidative stress, Antioxidant defence, Myelodysplastic syndromes, Iron overload, 8-oxo-dG, Superoxide anion
Abstract

Objective: To assess the generation of reactive oxygen species (ROS) and the involvement of the main antioxidant pathways in low/intermediate-1-risk myelodysplastic syndromes (MDS) with iron overload (IOL). Methods: We examined the levels of superoxide anion (O-2 center dot(-)), hydrogen peroxide (H2O2), antioxidants (glutathione, GSH; superoxide dismutase, SOD; catalase, CAT; and glutathione peroxidase, GPx), mitochondrial membrane potential (Delta Psi m), and by-products of oxidative damage (8-isoprostanes and 8-oxo-7,8-dihydro-2'-deoxyguanosine, 8-oxo-dG) in 42 MDS patients (28 without IOL at diagnosis, and 14 who developed IOL) and 20 healthy subjects. Results: Patients with IOL showed higher O-2 center dot(-) levels (39.4 MFI) than normal controls (22.7 MFI, p = 0.0356) and patients at diagnosis (19.4 MFI, p = 0.0049). Antioxidant systems, except SOD activity, exhibited significant changes in IOL patients with respect to controls (CAT: 7.1 vs 2.7 nmol/ml/min, p = 0.0023; GPx: 50.9 vs 76.4 nmol/ml/min, p = 0.0291; GSH: 50.2 vs 24.1 MFI, p = 0.0060). Furthermore, mitochondrial dysfunction was only detected in IOL cases compared to controls (Delta Psi m: 3.6 vs 6.4 MFI, p = 0.0225). Finally, increased levels of 8-oxo-dG were detected in both groups of patients. Conclusion: Oxidative stress is an important but non-static phenomenon in MDS disease, whose status is influenced by, among other factors, the presence of injurious iron.

Published
2017

6. The role of Dietitian in cardiac rehabilitation and prevention

Author

Brazzo S, Agostini S, Scapolo M, Masini Ml, da Vico L, and Biffi B

Subjects
Pulmonary and Respiratory Medicine, medicine.medical_specialty, Heart Diseases, medicine.medical_treatment, Psychological intervention, MEDLINE, role of Dietitian, lcsh:Medicine, Scientific literature, Disease, Professional Role, Nursing, medicine, Humans, Medical nutrition therapy, multidisciplinary strategies, Rehabilitation, business.industry, lcsh:R, cardiac rehabilitation, Italy, Family medicine, Position paper, Nutrition Therapy, Cardiology and Cardiovascular Medicine, business, Psychosocial
Abstract

Rehabilitation and secondary prevention programs are recognized as an essential part of the overall care of patients with cardiovascular disease. They consist of multidisciplinary strategies aiming at the reduction of modifiable risk factors for cardiovascular disease. Cardiac rehabilitation includes non-pharmacological interventions as: Patients’ evaluation. Nutritional counseling. Risk factors management (serum lipids, blood pressure, weight, diabetes, smoking). Psychosocial interventions. Physical activity and cardiovascular physical training counseling. Their effectiveness in the reduction of mortality through the decrease of risk factors has been proven in the last twenty years. Guidelines on appropriate and well-framed interventions have been released and nutritional interventions have a ringside seat in all programs. During 2007, the Italian Association of Dietitians, ANDID, created a working group of expert dietitians, with the goals of making a review of available scientific literature and of elaborating a Professional Position Papers on the role of Dietitian in cardiac rehabilitation and prevention. This Position Paper retrieves and remarks the available evidence that are important for the dietitians, according to their professional role and their contribution in the management of the topic.

Published
2016

7. Use of TALEN for a double gene extinction on two closely linked loci

Author

Teixeira, M., Bouleftour, W., Thomas, M., Concordet, J. P., Aubert, Denise, Machuca, Irma, Vico, L., Lafage-Proust, M. H., Malaval, L., Plateau de Biologie Expérimentale de la Souris, Partenaires INRAE, Institut National de la Santé et de la Recherche Médicale (INSERM), Institut de Génomique Fonctionnelle de Lyon (IGFL), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Recherche Agronomique (INRA)-École normale supérieure - Lyon (ENS Lyon), ProdInra, Migration, École normale supérieure de Lyon (ENS de Lyon)-Institut National de la Recherche Agronomique (INRA)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS), and École normale supérieure - Lyon (ENS Lyon)-Institut National de la Recherche Agronomique (INRA)-Université Claude Bernard Lyon 1 (UCBL)

Subjects
[SDV] Life Sciences [q-bio], [SDV]Life Sciences [q-bio], [INFO]Computer Science [cs], [INFO] Computer Science [cs], ComputingMilieux_MISCELLANEOUS
Abstract

International audience

Published
2014

8. The Artificial Gravity Platform (AGP); a Very Large Radius Centrifuge as Human Hypergravity Habitat

Author

Jack JWA van Loon, Albiol, J., Baeyens, J. P., Barakova, E., Belavy, D., Berte, J., Blanc, S., Bok, K., Bos, J., Boyle, R., Braak, L., Bravenboer, N., Carotenuto, L., Chouker, A., Clement, G., Cras, P., Cross, E., Custaud, M. A., DE ANGELIS, Marco, de Boever, P., de Haas, O., Delavaux, T., Delfos, R., Denise, P., Eekhoff, M., Eiken, O., Felsenberg, D., Fong, K., Fuller, C., Goswami, N., Grillner, S., Groen, E., Harlaar, J., Heer, M., Heglund, N., Hinghofer Szalkay, H., Hughes Fulford, M., Iwase, S., Karemaker, Jm, Langdahl, B., Linnarsson, D., Lobascio, C., Lüthen, C., Mayrhofer, M., Mekjavic, I., Monici, M., Moss, M., Mulder, E., Narici, M., Norsk, P., O’Gorman, D., Paloski, W., Poelma, C., Prisk, K., Rauterberg, M., Rutten, M., Schultz, L., Singer, P., Sommeria, J., Stegeman, D., Stephan, A., Stienen, G., Strollo, F., Stutte, G., Suedfeld, P., Tesch, P., Ullrich, O., van den Berg, R., van de Heyning, P., GJ van Heijst, Vico, L., Woodward, E., Young, L., and Wuyts, F. L.

Published
2014

9. The Artificial Gravity Platform, AGP a very Large Radius Human Centrifuge

Author

van Loon, J. J. W. A., Baeyens, Jp, Berte, J., Blanc, S., Braak, L., Bok, K., Bos, J., Boyle, R., Bravenoer, N., Eekhoff, M., Chouker, A., Clement, G., Cras, P., Cross, Cusaud, DE ANGELIS, Marco, de Dreu, C., Delavaux, T., Delfos, R., Poelma, C., Denise, P., Felsenberg, D., Fong, K., Fuller, C., Grillner, Groen, E., Harlaar, Heer, M., Neuss, Heglund, N., Hinghofer Szalkay, H., Goswami, N., Graz, Hughes Fulfordn, M., Iwase, S., Karemaker, J. M., Langdahl, B., Linnarsson, D., Lüthen, C., Manzey, Monici, M., Mulder, E., Narici, M., Norsk, P., Paloski, W., Prisk, K., Rutten, M., Singer, Stegeman, D., Stephan, A., Stienen, G., Suedfeld, P., Tesch, P., Ullrich, O., Van den Berg, R., Van de Heyning, P., Vautmans, L., Veyt, J., Vico, L., Woodward, Young, L., and Wuyts, F.

Published
2013

10. A systematic review of methods for tissue analysis in animal studies on orthodontic mini-implants

Author

Gritsch, K., Laroche, N., Morgon, L., Al-Hity, R., Vico, L., Colon, P., Grosgogeat, B., Tissu Osseux et Contraintes Mecaniques (LBTO), Université Jean Monnet [Saint-Étienne] (UJM)-Institut National de la Santé et de la Recherche Médicale (INSERM), Hospices Civils de Lyon (HCL), Laboratoire des Multimatériaux et Interfaces (LMI), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Université Paris Diderot - Paris 7 - UFR Odontologie (UPD7 Odontologie), Université Paris Diderot - Paris 7 (UPD7), Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS), and UFR Odontologie [UPD7]

Subjects
[SDV.IB.BIO]Life Sciences [q-bio]/Bioengineering/Biomaterials, ComputingMilieux_MISCELLANEOUS
Abstract

International audience

Published
2012

11. A Large Human Centrifuge for Exploration and Exploitation Research

Author

Loon, J. J. W. A., Baeyens, J. P., Berte, J., Blanc, S., Braak, L., Bok, K., Jelte Bos, Boyle, R., Bravenboer, N., Eekhoff, E. M. W., Chouker, A., Clement, G., Cras, P., Cross, E., Custaud, M. A., Angelis, M., Delavaux, T., Delfos, R., Poelma, C., Denise, P., Felsenberg, D., Fong, K., Fuller, C., Grillner, S., Groen, E., Harlaar, J., Heer, M., Heglund, N., Hinghofer-Szalkay, H., Goswami, N., Hughes-Fulford, M., Iwase, S., Karemaker, J. M., Langdahl, B. L., Linnarsson, D., Lüthen, C., Monici, M., Mulder, E., Narici, M. V., Norsk, P., Paloski, W., Prisk, K., Rutten, M., Singer, P., Stegeman, D. F., Stephan, A., Stienen, G. J. M., Suedfeld, P., Tesch, P., Ullrich, O., Den Berg, R., Heyning, P., Delahaye, A., Veyt, J., Vico, L., Woodward, E., Young, L., Wuyts, F. L., Oral and Maxillofacial Surgery / Oral Pathology, Clinical chemistry, Internal medicine, Rehabilitation medicine, Physiology, MOVE Research Institute, Kinesiology, Movement Behavior, and Research Institute MOVE

Published
2012

12. A Large Human Centrifuge for Exploration and Exploratory Research

Author

van Loon, J. J. W. A., Baeyens, Jp, Berte, J., Blanc, S., Braak, L., Bok, K., Bos, J., Boyle, R., Bravenoer, N., Eekhoff, M., Chouker, A., Clement, G., Cras, P., Cross, Cusaud, DE ANGELIS, Marco, de Dreu, C., Delavaux, T., Delfos, R., Poelma, C., Denise, P., Felsenberg, D., Fong, K., Fuller, C., Grillner, Groen, E., Harlaar, Heer, M., Neuss, Heglund, N., Hinghofer Szalkay, H., Goswami, N., Graz, Hughes Fulfordn, M., Iwase, S., Karemaker, J. M., Langdahl, B., Linnarsson, D., Lüthen, C., Manzey, Monici, M., Mulder, E., Narici, M., Norsk, P., Paloski, W., Prisk, K., Rutten, M., Singer, Stegeman, D., Stephan, A., Stienen, G., Suedfeld, P., Tesch, P., Ullrich, O., Van den Berg, R., Van de Heyning, P., Vautmans, L., Veyt, J., Vico, L., Woodward, Young, L., and Wuyts, F.

Published
2012

13. A Large Human Centrifuge for Exploration end Explotation Research

Author

van Loon, J. J. W. A., Baeyens, Jp, Berte, J., Blanc, S., Braak, L., Bok, K., Bos, J., Boyle, R., Bravenoer, N., Eekhoff, M., Chouker, A., Clement, G., Cras, P., Cross, Cusaud, DE ANGELIS, Marco, de Dreu, C., Delavaux, T., Delfos, R., Poelma, C., Denise, P., Felsenberg, D., Fong, K., Fuller, C., Grillner, Groen, E., Harlaar, Heer, M., Neuss, Heglund, N., Hinghofer Szalkay, H., Goswami, N., Graz, Hughes Fulfordn, M., Iwase, S., Karemaker, J. M., Langdahl, B., Linnarsson, D., Lüthen, C., Manzey, Monici, M., Mulder, E., Narici, M., Norsk, P., Paloski, W., Prisk, K., Rutten, M., Singer, Stegeman, D., Stephan, A., Stienen, G., Suedfeld, P., Tesch, P., Ullrich, O., Van den Berg, R., Van de Heyning, P., Vautmans, L., Veyt, J., Vico, L., Woodward, Young, L., and Wuyts, F.

Subjects
Hypergravity • Artificial gravity • Microgravity • Weightlessness • Centrifuge • Gravity continuum • Mars • Moon • Human exploration • Human Hypergravity Habitat
Published
2011

14. Constitutional thinness: unusual human phenotype of low bone quality

Author

Lang, François, Galusca, Bogdan, Zouch, M., Germain, Natacha, Bossu, Cécile, Frere, D., Lafague-Proust, M.-H., Thomas, T., Vico, L., Estour, Bruno, Dynamique des capacités humaines et des conduites de santé (EPSYLON), and Université de Montpellier (UM)-Université Paul-Valéry - Montpellier 3 (UPVM)-Université Montpellier 1 (UM1)

Subjects
[SCCO.PSYC]Cognitive science/Psychology
Abstract

International audience; CONTEXT: Low fat mass and hormonal or nutritional deficiencies are often incriminated in bone loss related to thinness. Constitutional thinness has been described in young women with low body mass index (BMI) but close-to-normal body composition, physiological menstruation, no hormonal abnormalities, and no anorexia nervosa (AN) psychological profile.OBJECTIVE: Our objective was to determine whether constitutional thinness is associated with impaired bone quality.DESIGN, SETTING, AND PARTICIPANTS: This was an observational, cross-sectional study on 25 constitutionally thin and 44 AN young women with similar low BMI (

Published
2008

17. Il sito: L'architettura

Author

Vico L., Vassallo, Di Ioia, and Moro

Subjects
Architettura, Roma, Villa_di_Livia, Realtà virtuale
Published
2007

18. L'interpretazione

Author

Vico L. and Vassallo

Subjects
Archeologia, Roma, Realtà_Virtuale, Villa_di_Livia
Published
2007

25. Développement d'un système d'analyse d'images numérisées pour l'histomorphométrie osseuse

Author

Chappard, D., Beigbeder, Michel, Alexandre, C., Vico, L., Palle, S., Riffat, G., Département Informatique - ENSMSE, École des Mines de Saint-Étienne (Mines Saint-Étienne MSE), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT), and Breuil, Florent

Subjects
[INFO.INFO-MO] Computer Science [cs]/Modeling and Simulation, [INFO.INFO-MO]Computer Science [cs]/Modeling and Simulation
Published
1985

26. Développement d'un système d'analyse d'images numérisées pour l'étude histomorphométrique du tissu osseux

Author

Beigbeder, Michel, Chappard, D., Alexandre, C., Vico, L., Palle, S., Riffat, G., Département Informatique - ENSMSE, École des Mines de Saint-Étienne (Mines Saint-Étienne MSE), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT), and Breuil, Florent

Subjects
[INFO.INFO-MO] Computer Science [cs]/Modeling and Simulation, [INFO.INFO-MO]Computer Science [cs]/Modeling and Simulation, ComputingMilieux_MISCELLANEOUS
Abstract

International audience

Published
1987

27. Bisphosphonate effects in rat unloaded hindlimb bone loss model: three-dimensional microcomputed tomographic, histomorphometric, and densitometric analyses

Author

Barou O, Marie-Helene Lafage-Proust, Martel C, Thomas T, Tirode F, Laroche N, Barbier A, Alexandre C, and Vico L

Subjects
Male, Analysis of Variance, Diphosphonates, Dose-Response Relationship, Drug, Tibia, Body Weight, Humerus, Hindlimb, Rats, Bone Density, Animals, Bone Resorption, Rats, Wistar, Tomography, Densitometry
Abstract

The effects of antiresorptive drugs on bone loss remain unclear. Using three-dimensional microtomography, dual X-ray/densitometry, and histomorphometry, we evaluated tiludronate effects in the bone loss model of immobilization in tail-suspended rats after 7, 13, and 23 days. Seventy-eight 12-week-old Wistar male rats were assigned to 13 groups: 1 baseline group, and for each time point, 1 control group treated with vehicle and three tail-suspended groups treated with either tiludronate (0.5 or 5 mg/kg) or vehicle, administered s. c. every other day, during the last week before sacrifice. In primary spongiosa (ISP), immobilization-induced bone loss plateaued after day 7 and was prevented by tiludronate. In secondary spongiosa (IISP), bone loss appeared at day 13 with a decrease in trabecular thickness and trabecular number (Tb.N) as assessed by three-dimensional microtomography. Osteoclastic parameters did not differ in tail-suspended rats versus control rats, whereas bone formation showed a biphasic pattern: after a marked decrease at day 7, osteoblastic activity and recruitment normalized at days 13 and 23, respectively. At day 23, the 80% decrease in bone mass was fully prevented by high-dose tiludronate with an increase in Tb.N without preventing trabecular thinning. In summary, at day 7, tiludronate prevented bone loss in ISP. After day 13, tiludronate prevented bone loss in ISP and IISP despite a further decrease in bone formation. Thus, the preventive effects of tiludronate in this model may be related to the alteration in bone modeling with an increase in Tb.N in ISP and subsequently in IISP.

28. Quantification of focal contacts in osteoblastic cells--effects of intermittent and continuous gravitational stresses

Author

Guignandon A, Usson Y, Laroche N, Vico L, Alexandre C, and Marie-Helene Lafage-Proust

Subjects
Osteosarcoma, Osteoblasts, Weightlessness, Cell Adhesion, Tumor Cells, Cultured, Animals, Fluorescent Antibody Technique, Bone Neoplasms, Centrifugation, Hypergravity, Space Flight, Vinculin, Rats
Abstract

Osteoblast morphology and attachment were studied during parabolic flight and during centrifugation. Cultures of osteosarcoma cells were exposed to gravitational changes and then analyzed for morphological changes and stained using immunofluorescence staining for vinculin. Changes in cell adhesion parameters and focal contact topography are presented and discussed.

29. First definition of Minimal Care model: The role of nurses, physiotherapists, dietitians and psychologists in preventive and rehabilitative cardiology,Documento preliminare alla definizione degli interventi Minimal Care infermieristici, fisioterapici, dietistici e psicologici attuabili nell'ambito della Cardiologia Riabilitativa e Preventiva

Author

Bettinardi, O., Da Vico, L., Antonia Pierobon, Iannucci, M., Maffezzoni, B., Borghi, S., Ferrari, M., Brazzo, S., Mazza, A., Sommaruga, M., Angelino, E., Biffi, B., Agostini, S., Masini, M. L., Ambrosetti, M., Faggiano, P., and Griffo, R.

32. Modern quantum chemistry with [Open]Molcas

Author

Dumitru-Claudiu Sergentu, Leon Freitag, Quan Manh Phung, Ernst D. Larsson, Liviu F. Chibotaru, Francesco Segatta, Per-Åke Malmqvist, Saumik Sen, Javier Segarra-Martí, Irene Conti, Marco Garavelli, Liviu Ungur, Artur Nenov, Alberto Baiardi, Morgane Vacher, Francesco Aquilante, Jesper Norell, Christopher J. Stein, Luis Seijo, Thomas Bondo Pedersen, Kristine Pierloot, Stefano Battaglia, Jochen Autschbach, Massimo Olivucci, Roland Lindh, Nicolas Ferré, Stefan Knecht, Ignacio Fernández Galván, Luca De Vico, Xuejun Gong, Igor Schapiro, Markus Reiher, Michael Odelius, Marcus Lundberg, Veniamin Borin, Mickaël G. Delcey, Laura Pedraza-González, Valera Veryazov, Alessio Valentini, Theory and Simulation of Materials (THEOS) and National Centre for Computational Design and Discovery of Novel Materials, University at Buffalo [SUNY] (SUNY Buffalo), State University of New York (SUNY), Laboratory of Physical Chemistry [ETH Zürich] (LPC), Department of Chemistry and Applied Biosciences [ETH Zürich] (D-CHAB), Eidgenössische Technische Hochschule - Swiss Federal Institute of Technology [Zürich] (ETH Zürich)- Eidgenössische Technische Hochschule - Swiss Federal Institute of Technology [Zürich] (ETH Zürich), Laboratoire de Chimie et Physique Quantiques (LCPQ), Institut de Recherche sur les Systèmes Atomiques et Moléculaires Complexes (IRSAMC), Institut National des Sciences Appliquées - Toulouse (INSA Toulouse), Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Institut National des Sciences Appliquées - Toulouse (INSA Toulouse), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC), The Hebrew University of Jerusalem (HUJ), Institute for Nanoscale Physics and Chemistry (INPAC), Université Catholique de Louvain = Catholic University of Louvain (UCL), Dipartimento di Chimica Industriale 'Toso Montanari', ALMA MATER STUDIORUM-Universitàdi Bologna, Università degli Studi di Siena = University of Siena (UNISI), Uppsala University, Angström Laboratory, Institut de Chimie Radicalaire (ICR), Aix Marseille Université (AMU)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), University of Vienna [Vienna], Dipartimento di Chimica 'G. Ciamician', Alma Mater Studiorum Università di Bologna [Bologna] (UNIBO), National University of Singapore (NUS), Laboratorium für Physikalische Chemie (ETH-LPC), Eidgenössische Technische Hochschule - Swiss Federal Institute of Technology [Zürich] (ETH Zürich), Lund University [Lund], Department of Chemistry-Angstrom, the Theoretical Chemistry Programme, Division of Theoretical Chemistry, AlbaNova University Center (ALBANOVA), Stockholm University, Department of Physics [Stockholm], Dipartimento di Chimica, Department of Biochemistry and Molecular Biology, University of Southern Denmark (SDU), Nagoya University, Catholic University of Leuven - Katholieke Universiteit Leuven (KU Leuven), Bowling Green State University (BGSU), Laboratoire de Chimie - UMR5182 (LC), Centre National de la Recherche Scientifique (CNRS)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-École normale supérieure - Lyon (ENS Lyon)-Institut de Chimie du CNRS (INC), Instituto de Ciencia de Materiales de Madrid (ICMM), Consejo Superior de Investigaciones Científicas [Madrid] (CSIC), Division of Quantum and Chemistry, Department of Chemistry [Imperial College London], Imperial College London, Dipartimento di Produzioni Animali, Università della Tuscia, Aquilante F., Autschbach J., Baiardi A., Battaglia S., Borin V.A., Chibotaru L.F., Conti I., De Vico L., Delcey M., Galvan I.F., Ferre N., Freitag L., Garavelli M., Gong X., Knecht S., Larsson E.D., Lindh R., Lundberg M., Malmqvist P.A., Nenov A., Norell J., Odelius M., Olivucci M., Pedersen T.B., Pedraza-Gonzalez L., Phung Q.M., Pierloot K., Reiher M., Schapiro I., Segarra-Marti J., Segatta F., Seijo L., Sen S., Sergentu D.-C., Stein C.J., Ungur L., Vacher M., Valentini A., Veryazov V., Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Centre National de la Recherche Scientifique (CNRS)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC), École normale supérieure de Lyon (ENS de Lyon)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Università degli studi della Tuscia [Viterbo], and Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Université Toulouse III - Paul Sabatier (UT3)

Subjects
Code (set theory), Computer science, molecular-dynamics, Ab initio, General Physics and Astronomy, Physics, Atomic, Molecular & Chemical, 01 natural sciences, analytical gradients, Computational methods, MATRIX RENORMALIZATION-GROUP, Computer software, Physics::Atomic Physics, Wave function, Excitation energies, self-consistent-field, 010304 chemical physics, Chemistry, Physical, Physics, Density matrix renormalization group, AB-INITIO CALCULATIONS, potential-energy surface, [CHIM.THEO]Chemical Sciences/Theoretical and/or physical chemistry, Chemistry, ELECTRONIC-STRUCTURE, Potential energy surfaces, Physical Sciences, Density functional theory, Quantum chemistry, Quantum mechanical/molecular mechanical calculations, SELF-CONSISTENT-FIELD, ab-initio calculations, ANALYTICAL GRADIENTS, electronic-structure, transition-metal-complexes, Electronic structure, Quantum chemistry software, computational spectroscopy, computational photochemistry, CASPT2 versus density functional theory, Molecular dynamics, 010402 general chemistry, reduced multiplication scheme, Computational science, 0103 physical sciences, Teoretisk kemi, POTENTIAL-ENERGY SURFACE, Physical and Theoretical Chemistry, Theoretical Chemistry, Science & Technology, STATE PERTURBATION-THEORY, matrix renormalization-group, X-ray absorption spectroscopy, TRANSITION-METAL-COMPLEXES, state perturbation-theory, 0104 chemical sciences, REDUCED MULTIPLICATION SCHEME, MOLECULAR-DYNAMICS
Abstract

MOLCAS/OpenMolcas is an ab initio electronic structure program providing a large set of computational methods from Hartree-Fock and density functional theory to various implementations of multiconfigurational theory. This article provides a comprehensive overview of the main features of the code, specifically reviewing the use of the code in previously reported chemical applications as well as more recent applications including the calculation of magnetic properties from optimized density matrix renormalization group wave functions. ispartof: JOURNAL OF CHEMICAL PHYSICS vol:152 issue:21 ispartof: location:United States status: published

Published
2020

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