Author: "Tokuyama, H" / Database: OpenAIRE - Searchworks@Jio Institute Digital Library Search Results

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Author: Tsuji, T, Noguchi, T, Niino, H, Matsuoka, T, Nakamura, Y, Tokuyama, H, Kuramoto, S, and Bangs, N
Published: 2005

Author: Tsuji, T, Matsuoka, T, Yamada, Y, Nakamura, Y, Ashi, J, Tokuyama, H, Kuramoto, S, and Bangs, NL
Published: 2005

Author: Huchon, P., Tokuyama, H., Géoazur (GEOAZUR 6526), Institut de Recherche pour le Développement (IRD)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Université Nice Sophia Antipolis (... - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire de la Côte d'Azur, Université Côte d'Azur (UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Université Côte d'Azur (UCA)-Centre National de la Recherche Scientifique (CNRS), Institut de Recherche pour le Développement (IRD)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Université Nice Sophia Antipolis (1965 - 2019) (UNS), and COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Université Côte d'Azur (UCA)-Université Côte d'Azur (UCA)-Centre National de la Recherche Scientifique (CNRS)
Abstract: Marine Geology, v. 187, n. 1/2, p. 1-2 [451], 2002; International audience
Published: 2002

Author: Yamago, S., Tokuyama, H., Nakamura, E., Prato, Maurizio, Wudl, F., S., Yamago, H., Tokuyama, E., Nakamura, Prato, Maurizio, and F., Wudl
Subjects: "
Published: 1993

Author: Tokuyama, H
Subjects: Mice, Inbred BALB C, hemic and immune systems, chemical and pharmacologic phenomena, DNA, Nitrophenols, Mice, Transplantation, Isogeneic, Animals, Lymphocyte Culture Test, Mixed, Haptens, Cell Division, Spleen, Research Article, Thymidine
Abstract: Spleen cells from normal BALB/c mice showed in vitro proliferative response against hapten-conjugated syngeneic spleen cells. Trinitrophenylated (TNP) spleen cells were prepared by treating normal spleen cells with sodium 2,4,6-trinitrobenzenesulphonate (TNBS). Four-day cultures of TNP-labelled spleen cells incorporated 2.5-7.4 times more [3H]thymidine than similar cultures of untreated spleen cells. An obviously positive mixed lymphocyte reaction (MLR) by normal spleen cells against mitomycin C (MC) treated TNP-labeled syngeneic spleen cells was observed after 4 days of culture. The MLR to TNP-labelled syngeneic cells was inhibited in the presence of epsilon-TNP-L-lysine by 23-37%. The spleen cells from the mice injected intraperitoneally with TNP-labelled syngeneic spleen cells showed a higher MLR against TNP-labelled spleen cells than normal spleen cells. The sensitized spleen cells also showed an increased response to MC-treated spleen cells. These results suggest that normal spleen cells include cells which can recognize the hapten and new antigenic determinants introduced into syngeneic spleen by chemical modification.
Published: 1975

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