1. Proximal Bone Remodeling in Lower Limb Amputees Reconstructed With an Osseointegrated Prosthesis
- Author
-
Thomson, S, Lu, W, Zreiqat, H, Li, JJ, Tetsworth, K, and Al Muderis, M
- Subjects
Adult ,Male ,0903 Biomedical Engineering, 1103 Clinical Sciences, 1106 Human Movement and Sports Sciences ,Bone-Anchored Prosthesis ,Artificial Limbs ,Middle Aged ,Orthopedics ,Amputees ,Lower Extremity ,Bone Density ,Humans ,Female ,Bone Remodeling ,Prospective Studies ,Aged - Abstract
Mobility outcomes and changes in bone mineral density (BMD) of the spine and femoral necks in response to unilateral osseointegrated implants was investigated over a 3-year period. A total of 48 unilateral amputees who received an osseointegrated implant, comprising 33 trans-femoral amputees (TFA) and 15 trans-tibial amputees (TTA), underwent dual-energy X-ray absorptiometry (DXA) scans of the lumbar spine (L2-L4) and femoral necks at baseline, 1-, and 3-years follow-ups. Mobility outcomes, including the Six-Minute-Walk Test (6MWT) and Timed-Up-and-Go (TUG), were measured before surgery, at 1 year, and more than 2 years following the osseointegration procedure. We observed a significant increase (p
- Published
- 2019