1. GABA levels in CSF of patients with psychiatric disorders
- Author
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M. B. Bowers, Roth Rh, B. I. Gold, and Sweeney Dw
- Subjects
Adult ,Male ,medicine.medical_specialty ,Psychosis ,Bipolar Disorder ,business.industry ,Depression ,Schizoaffective disorder ,Middle Aged ,medicine.disease ,Psychiatry and Mental health ,Lumbar ,Text mining ,nervous system ,Psychotic Disorders ,Internal medicine ,medicine ,Schizophrenia ,Humans ,In patient ,Female ,business ,Depression (differential diagnoses) ,gamma-Aminobutyric Acid ,Aged - Abstract
The authors measured gamma-aminobutyric acid (GABA) levels in the lumbar CSF of patients with depression, with psychosis, or undergoing evaluation for a neurologic disorder. GABA levels in the CSF from depressed patients were significantly decreased compared with neurologic control patients. CSF GABA levels in psychotic patients were not different from those in neurologic patients, although the data suggested a decrease in CSF GABA levels in patients with schizoaffective disorder.
- Published
- 1980