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Einstein assumed the “principle of relativity” when constructing the special theory of relativity (STR). He claimed that all inertial frames are equivalent, and that it is impossible to discriminate between inertial frames. However, among the coordinate systems regarded by Einstein as inertial frames, there are some in which light propagates isotropically, and some in which light propagates anisotropically. A method has been found which discriminates between these. This paper discusses the “triplet thought experiment” in which accelerated motion is eliminated from the famous twin paradox thought experiment of the STR. Here the inertial frames regarded as equivalent by the STR are identified as “classically stationary frames SCl” and “classically moving frames (S'Cl) ” First, an observer M in frame performs the triplet thought experiment, and it is confirmed that the delay in time which elapses in the moving frame agrees with the predictions of the STR. Next, an observer in rocket A (S'Cl) performs the triplet thought experiment, and observes the same time delay. Before starting movement at constant velocity, rocket A experiences accelerated motion. The coordinate system of rocket A cannot be regarded physically as a stationary frame. Even so, observer A observes the delay predicted by the STR. If it can be accepted that frames SCl are included in inertial frames, then the problem of the twin paradox will no longer be a paradox.

This paper discusses a thought experiment whose result contradict the predictions of the special theory of relativity. The reason why this contradiction appears is a velocity vector attached to an inertial frame. Since this sort of inertial frame exists in the natural world, the “principle of relativity” that regards all inertial frames as equivalent, cannot be regarded as a true principle. This paper concludes that the special theory of relativity, which assumes the “principle of relativity” in its development, is a theory with a built-in contradiction.

This paper discusses ultra-low energy levels of the hydrogen atom which was not predictable with quantum mechanics. In the energy-momentum relationship applicable to the electron in a hydrogen atom, derived by the author, there is a negative energy solution, just like the Einstein relationship which holds in free space. The matter formed from a proton with positive mass, and an electron with negative mass that orbits near that proton, is smaller than an ordinary hydrogen atom to an extreme degree. When this unknown matter gathers in large amounts, it becomes a huge mass. This paper identifies such matter as the true nature of dark matter, the mysterious matter that physicists are currently searching for

To explore reasons for differences in the malignancy of tumors, we have compared two cell lines derived from a mouse lung adenocarcinoma cell line that differ 10-fold in their capacity to form lung metastases from s.c. primary tumors or after i.v. injection. One mRNA encoding carbonyl reductase was identified at a relatively high abundance in the subline with low metastatic capacity but was not detectable in the highly metastatic subline. Transfection of the former subline with a plasmid construct expressing antisense carbonyl reductase rendered the cells highly metastatic. Conversely, the capacity of the highly metastatic cells to metastasize was markedly reduced after transfection with a construct expressing carbonyl reductase. We also found that human prostate cancers show loss of carbonyl reductase expression compared with normal prostate epithelia. These data suggest that carbonyl reductase has an important function in modifying the metastatic behavior of malignant tumors.