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Mihoko Kawamura, Yoshio Hirano, Munenori Yoshida, Takeshi Mizutani, Kazuhiko Sugitani, Tsutomu Yasukawa, Yuichiro Ogura Department of Ophthalmology & Visual Science, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan Purpose: The aim of this study is to report the 6-month results after one intravitreal ranibizumab (IVR) injection followed by pro re nata dosing for macular edema (ME) after branch retinal vein occlusion.Patients and methods: The inclusion criteria included a minimal patient age of 18 years, 20 letters or more best-corrected visual acuity (BCVA) (Early Treatment Diabetic Retinopathy Study [ETDRS] score, 77 letters or less), and central retinal thickness (CRT) of 250 microns or more. The primary outcome measure was the mean BCVA change from baseline at month 6; the secondary outcomes were mean changes in CRT, residual ME, and microaneurysm formation.Results: Twenty patients were enrolled from March 2014 through October 2016 at Nagoya City University Hospital. The baseline mean ETDRS letters and CRT were 63.1 and 500 microns, respectively; mean time from symptom onset to initial therapy was 1.80 months; and mean ETDRS gain and CRT reduction were 15.2 letters and 230 microns, respectively. The percentages of patients with Snellen equivalent BCVAs of 20/40 (70 ETDRS letters) or better and 20/20 (85 ETDRS letters) were 90% and 15%, respectively. Residual ME and microaneurysms were observed in 85% and 35% of patients. Microaneurysm formation was associated with delayed initial therapy.Conclusion: Prompt initiation of IVR injection provided a better visual prognosis at month 6 and suppressed the microaneurysm formation. Keywords: branch retinal vein occlusion, macular edema, microaneurysm, ranibizumab, prompt treatment

We present deep near-infrared (J, H, Ks) images toward an embedded cluster which lies in a C18O clump in the cloud C of the Vela Molecular Ridge. This cluster has at least ~ 350 members and a radius of ~ 0.5 pc. The stellar surface number density is approximately 3000 stars pc^-2 in the central 0.1 pc x 0.1 pc region of the cluster. This is much higher than most of the young clusters within 1 kpc of the Sun. From the comparison of the luminosity function and near-infrared excess fraction with those of other embedded clusters, we estimate that the age of this cluster is approximately 2-3 Myr. This cluster exhibits an excess of brighter stars in its central region, from which we conclude that the more massive stars are located near the cluster center., Comment: 23 pages, 8 figures. Color version of Figure 1 made available in gif format. Accepted 24 June 2004 for publication in the ApJ

We study the evolution of elliptical galaxies at z >~ 1 on the basis of a sample of 247 Extremely Red Objects (EROs) with R-Ks >= 3.35 (AB) and Ks ~ 1.5 found by several authors, we conclude that the majority of ellipticals seen at present have not established either a red color or a smooth 1/4-law profile before z ~ 1.5$. (abridged), 46 pages, 15 PostScript figures. Submitted to ApJ