Author: "Strupas, Kęstutis" / Database: OpenAIRE - Searchworks@Jio Institute Digital Library Search Results

63 results on '"Strupas, Kęstutis"'

1. Ultrasound-guided percutaneous laser ablation for papillary thyroid microcarcinoma: a literature review

Author: Beiša, Augustas, Gedvilaitė, Neda, Židonis, Žygimantas, Poškus, Tomas, Židonytė, Živilė, and Strupas, Kęstutis
Subjects: ultrasound therapy, thyroid microcarcinoma, PTMC, percutaneous laser ablation, laser ablation, OR and LA, Endocrinology, Endocrinology, Diabetes and Metabolism
Published: 2023
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2. The value of metformin in pancreatic ductal adenocarcinoma treatment

Author: Andriušaitytė, Urtė, Babonaitė, Elena, Kielaitė-Gulla, Aistė, and Strupas, Kęstutis
Subjects: Pancreatic ductal carcinoma, PDAC, pancreatic cancer, metformin
Published: 2022

3. Risk factors of hemorrhoids and fissures of pregnancy: results of the randomized controlled trial

Author: Sabonytė-Balšaitienė, Živilė, Poškus, Tomas, Ramašauskaitė, Diana, Drąsutienė, Gražina Stanislava, Šmigelskaitė, Mantė, Barkauskaitė, Gabija, Jakubauskas, Matas, Jakubauskienė, Lina, Jasiūnas, Eugenijus, Strupas, Kęstutis, and Vaitkevičiūtė, Dalia
Subjects: haemorrhoids and fissures, pregnancy, delivery
Published: 2021

4. On the computed tomography image data to diagnose pancreatic cancer using machine learning

Author: Šubonienė, Aušra, Kurasova, Olga, Medvedev, Viktor, Kielaitė-Gulla, Aistė, Samuilis, Artūras, Jagminas, Džiugas, Strupas, Kęstutis, and Dzemyda, Gintautas
Subjects: pancreatic cancer, machine learning, deep learning, CT, image segmentation
Published: 2021

5. Tumor growth through antiangiogenic activity in experimental colorectal liver metastasis

Author: Kvietkauskas, Mindaugas, Žitkutė, Viktorija, Leber, Bettina, Strupas, Kęstutis, Stiegler, Philipp, and Schemmer, Peter
Subjects: melatonin, glycine, colorectal cancer, liver metastases, anticancer drug combination
Abstract: Despite multimodal treatment strategies, clinical outcomes of advanced stage colorectalcancer (CRC) patients remain poor. Neoadjuvant/adjuvant chemotherapy efficacy is limited dueto chemoresistance, toxicity, and negative side effects. Since both melatonin and glycine have anti-cancer activities without relevant side effects, this study was designed to investigate their combinedeffects in experimental CRC liver metastases. CRC metastasis with CC531 cells were induced inmale Wistar rats. Melatonin and glycine alone or their combination were supplemented for14 days(n= 100). Blood parameters, a micro-computed tomography scan (tumor volume over time), andimmunohistochemistry for Ki67 and CD31 expression in tumor tissue were compared betweengroups. Melatonin and glycine alone significantly reduced the tumor volume by 63.2% (p= 0.002)and 43% (p= 0.044) over time, respectively, while tumor volume increased by 8.7% in the controls.Moreover, treatment with melatonin and glycine alone reduced the tumor proliferation index. Mostinterestingly, the combination therapy did not have any influence on the above-mentioned tumorparameters. The leukocyte count was significantly increased with melatonin at the end of theexperiment (p= 0.012) which was due to a high lymphocytes count. Tumor microvascular densitywas significantly reduced in all treatment groups. The results of this study suggest an inhibitoryfunction for melatonin and glycine alone in the case of CRC liver metastasis growth by acting asnatural antiangiogenic molecules, followed by angiogenesis-dependent cancer proliferation andimmunomodulation.
Published: 2021

6. Initial experience of minimally invasive gastrectomy for gastric cancer in Vilnius University Hospital Santaros Klinikos and National Cancer Institute: clinical case series and literature review

Author: Lukšta, Martynas, Sasnauskas, Gustas, Baušys, Augustinas, Rybakovas, Andrius, Kuliavas, Justas, Baušys, Rimantas, and Strupas, Kęstutis
Subjects: gastric cancer, minimally invasive surgery, literature review
Abstract: Background. Gastric cancer remains one of the most common cancers in Lithuania and Worldwide. Surgical treatment is the only potentially curative treatment option for it. Historically open gastrectomy was considered as the gold standard approach. Although, the development of minimally invasive surgery and accumulation of the clinical data has led to the adoption of minimally invasive gastrectomy. Clinical cases. We present a series of 8 clinical cases who underwent minimally invasive surgery for early or locally advanced gastric cancer in Vilnius University Hospital Santaros Klinikos and the National Cancer Institute. Discussion. Large scale randomized controlled trials in Asia have proved that laparoscopic surgery is safe and oncologically effective for clinical stage I distal gastric cancer. The increasing amount of data supports the safety of minimally invasive gastrectomy for advanced or proximal gastric cancer. Most of the trials performed in Asia confirmed, that laparoscopic gastrectomy has some advantages, including: decreased blood loss, decreased postoperative pain, and morbidity. Recent randomized controlled trials of Western countries proved the safety of laparoscopic gastrectomy and the comparable 1-year long-term outcomes. Although, they failed to show improved recovery after minimally invasive surgery. Currently, there is sufficient evidence to adopt minimally invasive gastrectomy for gastric cancer into routine clinical practice in Lithuania. Conclusions. The first experience of minimally invasive gastric cancer surgery in Vilnius University Hospital Santaros Klinikos and the National Cancer Institute was successful. All gastrectomies were radical, and without major postoperative complications.
Published: 2021

7. Kraujavimo po pankreatoduadeninių rezekcijų gydymo algoritmas

Author: Šileikis, Audrius, Misonis, Nerijus, Kurminas, Marius, Tumas, Jaroslav, and Strupas, Kęstutis
Published: 2019

8. Kolorektinės jungties tikrinimas metileno mėlio mėginiu operacijos metu

Author: Kryžauskas, Marius, Imbrasaitė, Ugnė, Poškus, Eligijus, Strupas, Kęstutis, and Poškus, Tomas
Published: 2019

9. Predictors of postoperative hypocalcemia occurring after a total thyroidectomy: Results of a prospective multicenter study

Author: Eismontas, Vitalijus, Šlepavičius, Algirdas, Janušonis, Vinsas, Žeromskas, Paulius, Beiša, Virgilijus, Strupas, Kęstutis, Dambrauskas, Žilvinas, Gulbinas, Antanas, and Martinkėnas, Arvydas
Subjects: udc:616.441-089, Thyroid gland, surgery, Thyroidectomy, adverse effects, Hypocalcemia, etiology
Abstract: Background. Thyroid surgeries are among the most common operations performed in the world. Hypocalcemia following total thyroidectomy is a common complication that is sometimes difficult to correct. The aim of this study is to determine the risk factors for hypocalcemia following total thyroidectomy and their clinical value. Subjects and Methods. From January 2015 through to April 2017, 400 patients were included in this prospective multicenter study. All patients underwent total thyroidectomy due to various thyroid diseases. The following risk factors were analyzed: pre-operative and post-operative biochemical blood parameters, clinical effects and factors related to surgery, the patient, and the disease. Results. Post-operative hypocalcemia developed in 257 patients (64.2%). Of them, 197 patients (76.7%) were diagnosed with asymptomatic hypocalcemia. Clinical symptoms were present in 60 of the 257 patients with hypocalcemia (23.3%). The statistically significant predictors of hypocalcemia were calcium and ionized calcium pre- and postoperatively (p ˂ 0.001), parathyroid hormone on day one following surgery (p ˂ 0.001), thyrotoxicosis ˂10 years before surgery (odds ratio 1.65, 95% CI 1.01−2.70, p = 0.046), the number of parathyroid glands found during surgery (odds ratio 0.52, 95% CI 0.38−0.70, p ˂ 0.001), ligation of the trunk of the left inferior thyroid artery (odds ratio 2.04, 95% CI 1.27−3.29, p = 0.003), ligation of the trunk of the right inferior thyroid artery (odds ratio 2.37, 95% CI 1.47−3.81, p ˂ 0.001), and the number of transplanted parathyroid glands (odds ratio 1.87, 95% CI 1.12−2.97, p = 0.015). In the multivariate analysis, age (odds ratio 1.05, 95% CI 1.01−1.09, p = 0.029) and gender (odds ratio 5.94, 95% CI 1.13−31.26, p = 0.035) were statistically significant predictors.
Published: 2018

10. Hypocalcemia 6–12 months following total thyroidectomy: Results of a prospective multicenter study

Author: Eismontas, Vitalijus, Šlepavičius, Algirdas, Janušonis, Vinsas, Žeromskas, Paulius, Beiša, Virgilijus, Strupas, Kęstutis, Dambrauskas, Žilvinas, Gulbinas, Antanas, and Martinkėnas, Arvydas
Subjects: udc:616.441-089, Thyroid gland, surgery, Thyroidectomy, adverse effects, Hypocalcemia, etiology
Abstract: Background. Thyroid surgeries are among the most common operations performed in the world. Hypocalcemia following total thyroidectomy is a common complication that is sometimes difficult to correct. e aim of this study was to compare two groups of patients: those with normocalcemia and hypocalcemia following total thyroidectomy upon discharge from the hospital and 6–12 months following surgery as well as to determine the clinical value. Subjects and Methods. From January 2015 through April 2017, 400 patients were included in this prospective multicenter study. All the patients underwent total thyroidectomy due to various thyroid diseases. The following risk factors were analyzed: pre-operative and post-operative biochemical blood parameters, clinical effects and factors related to surgery, the patient, and the disease. By way of random of selection, two groups of patients were formed: 30 patients who had a normal level of calcium detected in the blood upon discharge from the hospital following total thyroidectomy (normocalcemia group) and 30 patients who had a reduced level of calcium in the blood upon discharge from the hospital (hypocalcemia group). In these groups of the patients, the following parameters were determined: calcium, ionized calcium, 25-hydroxyvitamin D, parathyroid hormone, clinical expression of hypocalcemia, and the use of calcium and 25-hydroxyvitamin D preparations upon discharge from the hospital and 6–12 months following surgery. [...].
Published: 2018

11. Hemoroidinių arterijų embolizacija - naujas hemorojaus gydymo metodas: atvejo pristatymas

Author: Zaks, Natalja, Mažrimas, Povilas, Poškus, Tomas, Misonis, Nerijus, Sokolovas, Vitalijus, and Strupas, Kęstutis
Subjects: hemorrhoidal disease, embolization, superior rectal artery, emborrhoid
Abstract: Background / Objective Hemorrhoids are a very common anorectal condition, affecting millions of people around the world and represent major medical and socioeconomic problem. New technique for treating symptomatic hemorrhoids has been introduced in to clinical practice. Only limited number of cases using this technique were reported. This was a first clinical case in Lithuania using this technique for treating hemorrhoids. 44 year-old-man underwent liver transplantation for B viral cirrhosis in 2011. He developed liver transplant cirrhosis, hepatorenal syndrome, portal hypertension, hiperuricaemia. He presented to us with recurrent episodes of massive rectal bleeding, requiring multiple transfusions, with hemoglobin as low as 45 g/l. Several episodes of conservative treatment for hemorrhoids was not effective. Because of thrombocytopenia, risk of intra- and postoperative bleeding usual choice of surgical or minimally invasive treatment for hemorrhoids was not possible. The choice of selective angiography and embolization was made. On the 30th of July 2015 the patient underwent visceral and selective mesenteric angiograms. Inferior mesenteric artery was canulated. Terminal branches of the inferior rectal artery were embolized using Interblock 18 microspirals. Three spirals were used. Rectal bleeding stopped. Proctoscopy was performed after three weeks. Hemorrhoidal cushions were reduced by approximately 70%. No recurrent bleeding was observed 23 months after the procedure. The patient safely underwent repeated liver transplantation within 1 month. Conclusions Embolization of inferior rectal arteries requires multidisciplinary approach. Emborrhoid is a safe, effective microinvasive treatment for hemorrhoids in patients, who are otherwise at high risk for surgical complications.
Published: 2017

12. Transanalinė totalinė mezorektalinė ekscizija (taTME): pirmoji mūsų patirtis

Author: Mikalauskas, Saulius, Kryžauskas, Marius, Jurkevičiūtė, Dignė, Pečiulytė, Vytautė, Danys, Donatas, Poškus, Tomas, Jotautas, Valdemaras, Poškus, Eligijus, Beiša, Virgilijus, and Strupas, Kęstutis
Subjects: taTME, rectal surgery, minimally invasive surgery
Abstract: Transanal total mesorectal excision (taTME) is a new natural orifice translumenal endoscopic surgery modality combined of three rectal surgery techniques. Detailed analysis of the taTME is the object of this article. We submit the report of three taTME procedures for histologically confirmed rectal adenocarcinoma that were performed for the first time in Lithuania, Vilnius University Hospital Santariskiu Klinikos.
Published: 2016

13. Suaugusiųjų Hirschprungo ligos chirurginis gydymas subtotaline kolektomija: galima alternatyva

Author: Kildušis, Edvinas, Poškus, Tomas, and Strupas, Kęstutis
Subjects: adult Hirschsprung’s disease, constipation, megacolon, aganglionosis
Abstract: Adult Hirschsprung’s disease (AHD) is a rare and often undiagnosed condition. At present, only a limited number of cases have been reported. We managed a 19-year-old woman with rich history of chronic constipation and abdominal discomfort. Abdominal radiography and barium enema examination demonstrated massively dilated colon (up to 15 cm in diameter). Full-thickness rectal biopsy showed absence of ganglionic cells. AHD was diagnosed and subtotal colectomy with ileorectal anastomosis was performed. At five-year follow up, the patient had significantly improved defecation and quality of life and was extremely satisfied with the operation. AHD should be considered in patients with long-standing and refractory constipation with megacolon. We advocate a subtotal colectomy with ileorectal anastomosis as one of the possible surgical alternatives in such young patients.
Published: 2016

14. Tiesiosios žarnos iškritimo chirurginis gydymas - vieno centro patirtis

Author: Danys, Donatas, Kavaliauskaitė, Gintarė, Žalimas, Algirdas, Žeromskas, Paulius, Mikalauskas, Saulius, Jotautas, Valdemaras, Poškus, Eligijus, Strupas, Kęstutis, and Poškus, Tomas
Subjects: rectal prolapse, rectopexy, resection, laparoscopy
Abstract: Background No consensus on the optimal procedure for repair of rectal prolapse (RP) exist. We present the results of our 10 year experience of Vilnius University Hospital Santariskiu Klinikos. Patients and methods Retrospective review was performed of the patients, operated on for rectal prolapse between 2005 and 2016. Patients were divided into two groups – internal recal prolapse (IRP) and complete rectal prolapse (CRP). Perioperative data between two groups were analysed. Statistical data analysis was carried out using the SPSS 20.0 software. To assess the difference between rectal prolapse groups of statistical methods the χ2 test was used. Data were considered statistically significant at p < 0.05. Results 89 patients between 2005 and 2016 underwent surgical treatment for rectal prolapse at our department. IRP group included 52 (58,4%), CRP – 37 (41,6%) patients. The male/female ratio was 1/6,4, the mean age was 58,3±15,2 years. Defecography was performed for 29 (32,6%)patients in IRP group and for 12 (13,5%) – in CRP group (p
Published: 2016

15. Minimally invasive approach in the management of pancreatic pseudocysts

Author: Šileikis, Audrius, Beiša, Augustas, Kvietkauskas, Mindaugas, Stanaitis, Juozas, Aleknaitė, Aušra, and Strupas, Kęstutis
Subjects: minimally, invasive, pancreatic, pseudocysts
Abstract: invasive management options. Indications, early and late results of endoscopic and laparoscopic treatment options are being discussed. Aim To present experience in treatment of PP by laparoscopic pseudocystogastrostomy and endoscopic pseudocystogastrostomy and to compare results, feasibility and safety. Materials and methods A retrospective analysis of minimally invasive pancreatic pseudocysts treatment was performed and patients were divided in two groups according to performed drainage procedure. First group - laparoscopic pseudocystogastrostomy, second–endoscopic pseudocystogastrostomy. Groups were compared by age, gender, pancreatic pseudocyst’s age, diameter and localization, as well as intraoperative, early and late postoperative complications. Results Sixty-three patients underwent surgical intervention: 14 patients–laparoscopic pseudocystogastrostomy (group I), 49–endoscopic pseudocystogastrostomy (group II). Average cyst diameter: group I–118.6±45.2 mm, group II–115.3±34.3 mm, p=0.8. Neither in group I nor in group II intraoperative complications occurred. Early minor complications: group I–3 (21.4%), group II–10 (20.4%), p=0.93. Early major complications: group I–0, group II–6 (12.2%), p=0.17. Late postoperative complications: group I–0, group II–1 (2%), p=0.59. In group I there was no case, whereas in group II there was 6 (12.2%) cases of cyst recurrence, p=0.32. Conclusions We have found that both methods to be feasible, effective and safe. Endoscopic treatment should be stated as the first choice treatment approach for patients with pancreatic pseudocyst and only then it fails, laparoscopic pseudocystogastrostomy should be performed.
Published: 2016

16. Minimally invasive retroperitoneal necrosectomy in management of acute necrotizing pancreatitis

Author: Šileikis, Audrius, Beiša, Virgilijus, Beiša, Augustas, Samuilis, Artūras, Šerpytis, Mindaugas, and Strupas, Kęstutis
Subjects: Original Paper, retroperitoneal necrosectomy, retroperitoneoscopy, minimally invasive pancreatic necrosectomy, necrotizing pancreatitis
Abstract: Introduction One of the most important requirements in treatment of acute necrotizing pancreatitis is minimized invasion. Aim We are presenting experience in treatment of acute necrotizing pancreatitis by an original minimally invasive retroperitoneal necrosectomy technique, comparing our results to other studies, evaluating feasibility and safety, discussing advantages and disadvantages of this method. Material and methods We performed a retrospective analysis of 13 patients who had acute necrotizing pancreatitis with large fluid collections in retroperitoneal space and underwent retroperitoneal necrosectomy. Results There were eight males and three females aged between 24 and 60 years, average age was 42.8 ±9.2 years. The most common cause of pancreatitis was alcohol, 10 patients (76.9%). Average time between diagnosis and performance of operation was 25.7 ±11.3 days. One patient underwent eight repeated interventions: two retroperitoneal necrosectomies; five laparotomies; ultrasound-guided drainage. One patient underwent four reinterventions: lumbotomy; revision; two lavages. Three patients had two reinterventions: one had laparotomy and tamponation; one had two repeated retroperitoneal necrosectomies; third had one repeated retroperitoneal necrosectomy and one had ultrasound-guided drainage. Three patients needed one additional retroperitoneal necrosectomy. Five patients did not required additional interventions. 61.5% of our patients did not require more than one reintervention. Postoperative stay varied from 9 to 94 days, average 50.8 ±32.6 days. Conclusions Minimally invasive techniques should be considered as first-choice surgical option in treating patients with acute necrotizing pancreatitis. Pancreatic necrosis occupying less than 30% and with massive fluid collections in the left retroperitoneal space can be safely managed by minimally invasive retroperitoneal necrosectomy.
Published: 2012

17. Video-assisted loboisthmectomy by the subclavicular approach. A case report

Author: Beisša, Virgilijus, Sileikis, Audrius, Eismontas, Vitalijus, and Strupas, Kęstutis
Subjects: endocrine system, video-assisted thyroidectomy, endocrine system diseases, minimally invasive thyroidectomy, Case Report, thyroid surgery
Abstract: The main advantage of minimally invasive thyroidectomy is a good cosmetic effect. Minimally invasive video-assisted thyroidectomy (MIVAT) is performed without gas insufflation in contrast to endoscopic thyroidectomy. In general, MIVAT is carried out through an incision in the middle part of the neck, not covered with clothes. The MIVAT thyroid lobectomy can also be done through the subclavicular approach. We describe a case of a 19-year-old female patient with a tumour of the left side of the neck. Thyroid ultrasound scan (UST) with thyroid fine-needle aspiration and cytological examination (FNAC) were performed. Thyroid-stimulating hormone (TSH), free triiodothyronine (FT3) and anti-tyreoperoxidase (ATPO) were checked. Video-assisted hemithyroidectomy was performed through an incision below the left clavicle. Intraoperative pathology examination of the specimen was carried out. The UST showed a solitary 13 mm × 23 mm nodule in the left lobe of the thyroid, the FNAC showed benign pathology. Thyroid function tests were normal (TSH 0.90 mIU/l; FT3 4.70 pmol/l). Video-assisted hemithyroidectomy was done through the incision below the left clavicle. Histopathological examination proved thyroid hyperplasia nodosum. There were no intra- or postoperative complications. The patient was discharged on the second day. Clinical and cosmetic outcomes 2 months after surgery were good. Minimally invasive video-assisted thyroid lobectomy performed via the subclavicular area is feasible and provides good cosmetic outcomes.
Published: 2012

18. Dešiniosios hemikolektomijos vieno pjūvio laparoskopinė operacija: dviejų atvejų aprašymas

Author: Kryžauskas, Marius, Mikalauskas, Saulius, Drungilas, Mantas, Poškus, Tomas, Jotautas, Valdemaras, Poškus, Eligijus, Beiša, Virgilijus, and Strupas, Kęstutis
Subjects: SILS, right hemicolectomy, laparoscopic surgery
Abstract: Single incision procedures are evolving as part of minimally invasive surgery. In 2008, the SILS approach was first described for a right hemicolectomy. We report and describe the first two transumbilical single incision laparoscopic right hemicolectomies for benign disease, which were performed in Lithuania Vilnius University Hospital Santariskiu Klinikos.
Published: 2015

19. Abdominal lymphangiomas in adults: case report and literature review

Author: Šileikis, Audrius, Danys, Donatas, Žaldokas, Gytis, and Strupas, Kęstutis
Subjects: body regions, lymphangioma, cavernous, cystic
Abstract: Intraabdominal lymphangioma is rare and comprises 5% of all lymphangiomas. In adults, it is less common than in children, and because of a benign progress lymphangioma is usually asymptomatic and its diagnosis is quite difficult. However, it is recommended to extirpate lymphangioma surgically to avoid complications. There is the question if lymphangioma should be completely excised to avoid relapses. We present a case of cavernous lymphangioma in an adult male who underwent a partial resection of the tumour. After ten years of observation, there is no evidence of tumour recurrence.
Published: 2015

20. Gigantinė retroperitoninio tarpo lipoma: klinikinis atvejis ir literatūros apžvalga

Author: Kulikauskas, Edgaras, Poškus, Eligijus, Rutkauskaitė, Dileta, and Strupas, Kęstutis
Subjects: body regions, retroperitoneal space, lipoma, surgery
Abstract: Primary retroperitoneal tumours are rare and show a high histological variety. About 80% of retroperitoneal tumours are malignant; benign lipomas in this location are exceptionally rare. These slow-growing tumors can grow up to more than 20 cm and weight a few kilograms. The differential diagnosis of lipomas with liposarcomas may be problematic, especially for tumours with low-grade malignancy, which have a predilection for local recurrence but do not generally metastatize. Fatty tumours of the retroperitoneum should be considered to be potential liposarcomas until proven otherwise, and a radical lesion excision should always be performed, if possible. We report a case of a giant retroperitoneal lipoma in a 61-year-old male. A CT scan of his abdomen showed a large mass of fat density displacing organs to the right side. The patient underwent a radical tumour excision. Laparotomy showed a giant fatty mass measuring 40 x 40 x 20 cm and weighing 6500 g. The pathological examination revealed benign lipoma. The patient was discharged home on postoperative day 9.
Published: 2012

21. Echinococcosis. First results of Lithuania Echinococcosis Registry

Author: Strupas, Kęstutis, Sokolovas, Vitalijus, Brimas, Gintautas, Paškonis, Marius, Jurgaitis, Jonas, Valantinas, Jonas, Buivydienė, Arida, Brimienė, Vilma, Dementavičienė, Jūratė, Samuilis, Artūras, Nepomniaščis, Dimitrijus, Marcinkutė, Audronė, and Barakauskienė, Aušrinė
Subjects: udc:616.995.121, lcsh:Surgery, Echinococcosis, Diagnosis, Treatment, Registry, lcsh:RD1-811
Abstract: Kestutis Strupas 1 , Vitalijus Sokolovas 1 , Gintautas Brimas 1 , Marius Paskonis 1 , Jonas Jurgaitis 1 , Jonas Valantinas 1 , Arida Buivydienė 1 , Jūratė Dementavicienė 2 , Artūras Samuilis 2 , Dimitrijus Nepomniascis 2 , Audronė Marcinkutė 3 , Ausrinė Barakauskienė 4 1 Vilniaus universiteto ligoninės Santariskių klinikų Gastroenterologijos, urologijos ir abdominalinės chirurgijos klinika, Santariskių g. 2, LT-08661 Vilnius 2 Vilniaus universiteto ligoninės Santariskių klinikų Radiologijos klinika, Santariskių g. 2, LT-08661 Vilnius 3 Respublikinė tuberkuliozės ir infekcinių ligų universitetinė ligoninė, Birutės g.1/20, LT-08117 Vilnius 4 Valstybinis patologijos centras, P. Baublio 5, LT-08406 Vilnius El pastas: kestas.strupas@mf.vu.lt Echinokokozės – tai parazitinės ligos, sukeliamos kaspinuocio, Echinococcus genties biohelmintų lervų. Europoje yra paplite E. granulosus, sukeliantis cistine echinokokoze (CE), ir E. multilocularis, sukeliantis alveokokine echinokokoze (AE). Sergamumas CE svyruoja nuo 1 iki 220 atvejų is 100 000 gyventojų. Sergamumas AE yra mažesnis – apie 0,3–1,2 atvejų is 100 000 gyventojų. Taciau mirstamumas yra didelis ir siekia > 90%. Echinokokozė specifinių simptomų neturi, o klinika priklauso nuo ligos sukėlėjo, stadijos, darinių dydžio ir lokalizacijos. Liga dažniausiai nustatoma atsitiktinai arba atsiradus komplikacijų. Sergant CE komplikacijas sukelia spaudimo reiskiniai, o sergant AE jas sukelia echinokokas, peraugdamas svarbias organų struktūras. Echinokokozės diagnostikai naudojami serologiniai (ELISA), radiologiniai (sonoskopija, KT, MRT) tyrimai. Nustacius echinokokoze taikomi įvairūs gydymo būdai. Jie priklauso nuo ligos sukėlėjo ir isplitimo. Bendrai abiem sukėlėjams gydyti vartojami benzimidazolo karbamatai (mebendazolis ir albendazolis). Be medikamentinio gydymo, CE atveju galima taikyti PAIR metodą, radiodažnine destrukciją, radikalų chirurginį gydymą. Nustacius AE, atsižvelgiant į isplitimą, taikomas radikalus chirurginis arba paliatyvus gydymas. Kadangi liga Europoje yra paplitus, 1998 metais buvo įkurtas Europos echinokokozės registras. Sergantys echinokokoze ligoniai Lietuvoje stebimi ir gydomi VU Infekcinėje ligoninėje nuo 1997 metų. 2003 m. birželio 6 d. VUL Santariskių klinikose įkurtas Lietuvos echinokokozės registras. 2004 m. rugpjūcio 14 d. Lietuvos echinokokozės registras įtrauktas į Europos echinokokozės registrą. Siuo metu registre yra 76 ligoniai, is jų 18 serga CE, 58 – AE. Radikaliai gydyti 25 pacientai. Paliatyvus gydymas buvo taikytas 39 ligoniams. Septyni ligoniai mirė. Echinokokozė yra reta pavojinga liga. Jos diagnostikos ir gydymo kokybė bei rezultatai priklauso nuo tarpdalykinės gydytojų koordinacijos efektyvumo. Echinokokozės registras garantuoja optimalią ligonių stebėjimo ir gydytojų veiksmų koordinacijos sistemą. Pateikti pirmieji Lietuvos echinokokozės registro duomenys rodo, kad gydymo rezultatai panasūs į pateikiamus Europos echinokozės registro suvestinėje. Pagrindiniai žodžiai: echinokokozė, diagnostika, gydymas, registras Echinococcosis. First results of Lithuania Echinococcosis Registry Kestutis Strupas 1 , Vitalijus Sokolovas 1 , Gintautas Brimas 1 , Marius Paskonis 1 , Jonas Jurgaitis 1 , Jonas Valantinas 1 , Arida Buivydienė 1 , Jūratė Dementavicienė 2 , Artūras Samuilis 2 , Dimitrijus Nepomniascis 2 , Audronė Marcinkutė 3 , Ausrinė Barakauskienė 4 1 Vilnius University Hospital "Santariskių klinkos", Department of Gastroenterology, Urology and Abdominal Surgery, Santariskių str. 2, LT-08661 Vilnius, Lithuania 2 Vilnius University Hospital "Santariskių klinkos", Department of Radiology, Santariskių str. 2, LT-08661 Vilnius, Lithuania 3 National Tuberculosis and Infectious Diseases University Hospital, Birutės str. 1/20, LT-08117 Vilnius, Lithuania 4 National Pathology Center, P. Baublio str. 5, LT-08406 Vilnius, Lithuania E-mail: kestas.strupas@mf.vu.lt Echinococcosis is a zoonotic infection caused by larval stages of cestodes belonging to the genus Echinococcus. Cystic echinococcosis (CE), caused by Echinococcus granulosus, and alveolar echinococcosis (AE), caused by E. multilocularis, are mostly spread in Europe. The annual incidence rates of CE vary between 1 to 220 per 100,000 population. The incidence of AE cases is lower and varies between 0.3–1.2 per 100 000 population, but morbidity reaches up to 90%. Echinococcosis has no specific symptoms, and its clinical presentation depends on many factors such as the type of parasite, stage of disease, localisation in the organ and its extent. Symptom-free echinococcosis is diagnosed occasionally or with appearance of complications. In case of CE, complications appear due to organ compression and in case of AE due to overgrowth of important organ structures. The diagnostic repertoire includes imaging techniques (US, CT, MBR) and immunodiagnostic tests. Chemotherapy with benzimidazoles (mebendazol or albendazol) is common in the treatment of bouth types of the disease. Treatment options for CE include surgery, PAIR and RFA. For AE, the first choice of treatment is radical surgical resection of the entire parasitic lesion or palliative treatment for inoperable cases. Because of the wide distribution of echinococcosis in Europe, the European Echinococcosis Registry was established in 1998. Lithuanian patients with echinococcosis were started to treat in 1997 at the Vilnius University Hospital of Infectious Diseases. On 6 June 2003, the Lithuanian Echinococcosis Registry was established at Vilnius University Hospital Santariskių Klinikos, and on 14 August 2004 it joined the European Echinococcosis Registry. Until 2007, 76 cases of echinococcosis were registered in the Lithuanian Echinococcosis Registry, including 18 cases of CE and 58 of AE. Radical surgical treatment was applied to 25 patients and palliative treatment to 39 patients. Seven patients died during the period of 4 years due to extention of the disease. Echinococcosis is a rare and dangerous disease. To enhance its treatment and diagnostic abilities, coordination among various specialists is necessary, and it is ensured by the Echinococcosis Registry. The first results of treatment presented in the Lithuanian Echinococcosis Registry are similar to the results presented in the European Echinococcosis Registry. Key words: echinococcosis, diagnosis, treatment, registry
Published: 2007

22. Shouldice, Lichtensteino ir laparoskopinių TAPP kirkšninių išvaržų operacijų lyginamasis daugiacentris perspektyvus atsitiktinių imčių klinikinis tyrimas: lėtinis skausmas ir gyvenimo kokybės pokyčiai

Author: Lipnickas, Vytautas, Kiudelis, Mindaugas, Gradauskas, Audrius, Kaselis, Nerijus, Narmontas, Deividas, and Strupas, Kęstutis
Subjects: groin hernia, health-related quality of life, SF-36, chronic pain
Abstract: Background / objective Open anterior inguinal hernia repair is a time-tested, safe and well-understood operation with a high success rate, while laparoscopic techniques are fairly recent. However, the best surgical approach to the repair of inguinal hernias is still unclear. Given their similarity in terms of complications and recurrence rate, other issues associated with these surgical techniques become more important. One of them is the quality of life. Methods The prospective randomized multicenter clinical study was performed in four surgical centers of Lithuania in 2003. 248 patients were operated on according to standardized protocols of Shouldice, Lichtenstein and laparoscopic TAPP inguinal hernia repairs. Chronic pain and changes of the quality of life according to the SF-36 questionnaire and ad hoc questionnaire of physical status were compared. Results The significantly higher scores in the physical functioning, role-physical, bodily pain and social functioning scales for laparoscopic hernia repair at 2 weeks postoperatively were apparent. The laparoscopic group had significantly less pain (p < 0.001). The significantly higher scores in the role-physical scale for laparoscopic to both open hernia repair methods at 6 months after operation were found (p < 0.05). The laparoscopic group had significantly less chronic pain 6 months postoperatively (p < 0.01). No significant difference in quality of life among three methods one year after operation was apparent. The laparoscopic group had less chronic pain one year after operation, but the difference was not significant ...
Published: 2007

23. Virškinimo trakto stromos navikų diagnostika ir gydymas

Author: Lipnickas, Vytautas, Adomavičiūtė, Jurgita, Valiukėnas, Valmontas, and Strupas, Kęstutis
Subjects: GIST, CD 117, CD 34, Imatinib, neoplasms
Abstract: Objectives. First, to review the latest issues concerning the management of gastrointestinal stromal tumours (GIST), the pathogenesis of these tumours, clinical manifestation, diagnostic possibilities, prognosis of biologic behaviour, management of treatment. Second, to analyse retrospectively the experience of patients with GIST treated at Vilnius University Hospital "Santariškių klinikos". Methods. The current issues of 2002–2006 on gastrointestinal stromal tumours in the Lithuanian and English languages have been reviewed. A retrospective study of patients with GIST at the Center of Abdominal Surgery of Vilnius University Hospital "Santariškių Klinikos" was done. Results. Gastrointestinal stromal tumours, being the most common nonepithelial mesenchymal tumours of gastrointestinal tract, account for only 1–3% of all gastrointestinal tract malignancies. According to the literature data, the tendency of GIST cases is increasing. Their clinical manifestation varies a lot, besides, there are up to 77% of asymptomatic cases, uncertain localization, all making the diagnosis difficult. Contrast-enhanced CT scan is a standard imaging for patients with suspected GIST. Until the era of Imatinib, surgery had been the only effective treatment. But even after apparently "curative" surgical resections the long-term results were poor, because up to 90% of cases GIST relapse. The liver is the most common site of recurrence (up to 70%). The discovery of Imatinib acting as a molecular target drug is hopeful. However, Imatinib chemotherapy is still at the experimental level, there are no exactly defined indications, duration of treatment, there are difficulties in evaluating tumour response to treatment. So there are unresolved questions in the management of GIST, such as neo-adjuvant or adjuvant therapy, the role of surgery in patients with differential or partial response to Imatinib, and the role of surgery in patients with isolated metastases...
Published: 2006

24. Trimatės kompiuterinės vizualizacijos taikymas kepenų chirurgijoje

Author: Jurgaitis, Jonas, Paškonis, Marius, Samuilis, Artūras, Volf, Ivo, Schöbinger, Maks, Brimas, Gintautas, and Strupas, Kęstutis
Subjects: genetic structures
Abstract: Three-dimensional (3D) liver visualization is a new tool in liver surgery planning. In most cases, plain or two-dimensional radiological images are hardly perceptible and understandable by the clinician. 3D visualization helps in the perception and interpretation of radiological images. 3D liver visualization are is mostly used before living related liver transplantation and in extended liver resections. In this article, we discuss the usefulness and employment of 3D visualization in clinical practice. Method We observed the whole 3D liver image formation process using OrgaNicer program and present a case report on 3D liver visualization employment in the clinical practice of Vilnius University Santariðkiø Cinics Hospital. Results Benefits of 3D liver visualization: helps in easy perception of difficult liver anatomy and anatomical liver variations; helps to define the surgical plan of liver resection and the extent of operation; precise liver volume calculation increases the safety of the operation. Disadvantages of 3D liver visualization: it is necessary to obtain good quality computer tomography images; long duration (40 to 240 min); a wide range of different specialists and their close cooperation are needed; the lack of defined clinical indications for visualization. Conclusions The new tool for liver surgery planning opens new perspectives in liver surgery, but the difficult course of the process, problems with integration into practice and the lack of clinical indications restrict its use. To increase its employment, indications for three-dimensional liver visualization must be defined and attention must be paid to increasing the quality of small volume liver resection using the new tool.
Published: 2006

25. Shouldice, Lichtensteino ir laparaskopinių transabdominalinių preperitoninių kirkšninių išvaržų operacijų ankstyvieji rezultatai: daugiacentrinis atsitiktinių imčių klinikinis tyrimas =

Author: Lipnickas, Vytautas, Kiudelis, Mindaugas, Gradauskas, Audrius, Kaselis, Nerijus, and Strupas, Kęstutis
Subjects: udc:616.34-007.43-031:611.957, Hernia, inguinal, Surgery, Laparoscopy, Methods, 616.34-007.43-031:611.957 [udc]
Abstract: Background / objective. Open anterior inguinal hernia repair is a time-tested, safe and well-understood operation with a high success rate, while laparoscopic techniques are fairly recent; their short- and long-term outcomes are still being evaluated, but the best method of inguinal hernia repair is still unclear. Methods. A prospective randomized multicenter clinical trial was performed in four surgical centers of Lithuania. Patients were operated on from January to December, 2003. Intraoperative, early and late postoperative complications, time of operation, hospital stay, postoperative pain evaluation, frequency of recurrence and changes of quality of life of laparoscopic TAPP (n = 82), Lichtenstein (n = 81) and Shouldice (n = 85) hernia repair were compared. Results. The mean operative time in the laparoscopic TAPP group was significantly longer than the mean operative time in Lichtenstein and Shouldice hernia repair group. There were no major intraoperative complications and only two postoperative wound infections in the Shouldice and Lichtenstein group. There was no difference in the frequency of minor intraoperative and early postoperative complications in the groups. The mean pain scores in the laparoscopic TAPP group were significantly lower than the corresponding scores in the Lichtenstein and Shouldice group (p < 0.05 at 8 h after operation and p < 0.01 at 24 h after operation). Statistically significant differences were found in hospital stay, the shortest stay being recorded in the laparoscopic TAPP group (p = 0.026 comparing laparoscopic TAPP and Lichtenstein hernia repair). 36 (42.3%) patients in the Shouldice and 23 (28.4%) in the Lichtenstein group felt a moderate or mild pain 2 weeks postoperatively, while there were only 2 (2.4%) patients with a mild pain in the laparoscopic TAPP group [...].
Published: 2006

26. Tiesiosios žarnos navikų gydymas transanaline endoskopine mikrochirurgija

Author: Jotautas, Valdemaras, Strupas, Kęstutis, Poškus, Egidijus, and Šeinin, Dmitrij
Subjects: Tiesioji žarna--Endoskopinė chirurgija, udc:616-006, Rectum--Endoscopic surgery, Rectum--Tumors, Rectum, Tiesioji žarna--Navikai, udc:616.3
Abstract: Darbo tikslas. Įvertinti pusantrų metų patirtį Lietuvoje, gydant tiesiosios žarnos navikus transanaline endoskopine mikrochirurgija Vilniaus universiteto ligoninės „Santariškių klinikos“ Pilvo chirurgijos centre. Tyrimo medžiaga ir metodai. Operacijoms buvo atrenkami ligoniai, sergantys tiesiosios žarnos adenomomis ir mažos rizikos piktybiniais navikais: T1 stadijos, geros ir vidutinės diferenciacijos, be invazijos į limfagysles ir kraujagysles. Naviko stadija iki operacijos nustatyta, atlikus transanalinę endosonoskopiją ir rektoskopiją su dauginėmis makrobiopsijomis. Rezultatai. Operuoti 47 ligoniai. Navikų dydžio vidurkis 3,4±1,4 cm (svyravo nuo 1 iki 7 cm). Iš viso pašalinti 25 (52, 1 proc.) piktybiniai navikai ir 23 (47,9 proc.) adenomos. Ikioperacinės ir galutinės klinikinės diagnozės nesutapo 14 (29,8 proc.) ligonių. Padarytos 43 (89,6 proc.) radikalios operacijos (R0), 5 (10,6 proc.) – abejotino radikalumo (RX). Konstatuota 1 (2,1 proc.) intraoperacinė ir 1 (2,1 proc.) pooperacinė komplikacija. Trims ligoniams po CaT2 pašalinimo taikyta adjuvantinė radioterapija. Stebėti 26 ligoniai praėjus 3–17 mėn. po operacijų: 17 po piktybinių navikų, 9 – po adenomos pašalinimo. Nustatytas 1 (2,1 proc.) tubuloviliozinės adenomos recidyvas. Kitų komplikacijų nekonstatuota. Išvados. Ankstyvieji transanalinės endoskopinės mikrochirurgijos rezultatai, gydant tiesiosios žarnos adenomas ir mažos rizikos T1 vėžį, yra geri. Mažas komplikacijų ir navikų recidyvo pro¬centas šioje grupėje... [toliau žr. visą tekstą] Objective. The aim of this study was to assess one and a half years experience gained in Lithuania while treating rectal tumors with transanal endoscopic microsurgery in the Centre of Abdominal Surgery of Vilnius University Hospital “Santariškių klinikos“. Materials and methods. The patients who had rectal adenomas and low-risk T1 carcinomas of good or moderate differentiation, with no lymphatic and vascular invasion were selected for surgery. Tumor stage was determined by transanal endosonoscopy and rectoscopy with multiple macrobiopsies before surgery. Results. A total of 47 patients were operated on. The average tumor size was 3.4±1.4 cm (ranged from 1 to 7 cm). Overall 25 (52.1%) carcinomas and 23 (47.9%) adenomas were removed. Pre-operative diagnoses did not correspond to the final clinical diagnoses in 14 (29.8%) cases. Forty-three (89.6%) radical operations (R0) and 5 (10.6%) doubtful complete operations (RX) were performed. One (2.1%) intra-operative complication and one (2.1%) post-operative complication were observed. After the removal of Ca T2 three patients underwent adjuvant radiotherapy. Twenty-six patients were followed up for 3–17 months after operation: 17 after removal of cancer and 9 after removal of adenoma. One (2.1%) recurrence of a tubulovillous adenoma was diagnosed. No other complications were reported. Conclusions. Initial results of transanal endoscopic microsurgery obtained while treating rectal adenomas and low-risk T1 cancers are promising. The... [to full text]
Published: 2005

27. Nauja skydliaukės masės ir tūrio matavimo ultragarsu metodika

Author: Žeromskas, Paulius, Bubnys, Algimantas Justinas, and Strupas, Kęstutis
Subjects: animal structures, endocrinolog, thyroid gland mass, thyroid gland tissue volume, thyroidectomy, volumetry
Abstract: Background / objective A new method of thyroid gland volume and mass measurement by ultrasound was elaborated at the Clinic of Abdominal Surgery of Vilnius University. Methods The method was proposed after ultrasonic pre-operative measurement (by our approach) and post-operative weighing and volume measurement of 187 thyroid lobes and 88 isthmuses. Results / conclusions We found that the volume of 1g of thyroid gland tissue is 0.958 ml and the difference is statistically significant. Thus, thyroid mass and volume must be calculated separately. To measure the size of the thyroid gland according to the new method, the following mathematical formulas are suggested: Vist = 0.991 × A × B × C, Mist = 1.051× A × B × C, Vlob = 0.49 × A × B × C, Mlob = 0.508 × A × B × C, where Vist is the isthmus volume, Mist is the isthmus weight, Vlob is the lobe volume, Mlob is the lobe weight, A is lobe (or isthmus) length, B is lobe (or isthmus) width, C is lobe (or isthmus) depth. The volume (or mass) of the thyroid gland is the sum ultrasonically determined volumes (or masses) of the both lobes and the isthmus. The accuracy of the method has been ascertained by comparing the ultrasonically determined volume (and weight) with the volume (and weight) of the same gland removed surgically. The correlation coefficient was r=0.97 (n=71). The method is adapted to ordinary ultrasound equipment.
Published: 2003

28. Dirbtiniais neuroniniais tinklais paremtos visiškai automatizuotos II-III kepenų segmentų voliumetrijos prieš virtualią išplėstinę dešiniąją hemihepatektomiją palyginamasis įvertinimas

Author: Gudaitė, Jogailė, Tamulevičius, Martynas, Jakubauskas, Matas, and Strupas, Kęstutis
Published: 2021

29. Dirbtiniais neuroniniais tinklais paremtos visiškai automatizuotos VI-VII kepenų segmentų voliumetrijos prieš virtualią išplėstinę kairiąją hemihepatektomiją palyginamasis įvertinimas

Author: Stuopelytė, Raminta, Tamulevičius, Martynas, Jakubauskas, Matas, and Strupas, Kęstutis
Published: 2021

30. Dirbtiniais neuroniniais tinklais paremto visiškai automatizuoto kepenų venų segmentavimo palyginamasis įvertinimas

Author: Kručaitė, Rugilė, Tamulevičius, Martynas, Jakubauskas, Matas, and Strupas, Kęstutis
Published: 2021

31. Timing of surgery following SARS-CoV-2 infection: an international prospective cohort study

Author: Dmitri, Nepogodiev, Joana Ff Simoes, Elizabeth, Li, Maria, Picciochi, James, C Glasbey, Glauco, Baiocchi, Ruth, Blanco-Colino, Daoud, Chaudhry, Ehab, Alameer, Kariem, El-Boghdadly, Funmilola, Wuraola, Dhruva, Ghosh, Rohan, R Gujjuri, Ewen, M Harrison, Herman, Lule, Haytham, Kaafarani, Mohammad, Khosravi, Irmgard, Kronberger, Sezai, Leventoğlu, Harvinder, Mann, Kenneth, A Mclean, Mengistu Gebreyohanes Mengesha, Maria Marta Modolo, Faustin, Ntirenganya, Lisa, Norman, Oumaima, Outani, Riinu, Pius, Peter, Pockney, Ahmad Uzair Qureshi, April Camilla Roslani, Sohei, Satoi, Catherine, Shaw, Aneel, Bhangu, Omar, M Omar, Waheed-Ul-Rahman, Ahmed, Leah, Argus, Alasdair, Ball, Edward, P Bywater, Amanpreet, Brar, Brett, E Dawson, Irani, Duran, Muhammed, Elhadi, Conor, S Jones, Sivesh, K Kamarajah, James, M Keatley, Samuel, Lawday, Ella, J Marson, Riinu, Ots, Irène, Santos, Elliott, H Taylor, Isobel, M Trout, Chris, Varghese, Mary, L Venn, William, Xu, Irida, Dajti, Arben, Gjata, Salah Eddine Oussama Kacimi, Luis, Boccalatte, Daniel, Cox, Philip, Townend, Felix, Aigner, Irmgard Elisabeth Kronberger, Elgun, Samadov, Amer, Alderazi, Kamral, Hossain, Greg, Padmore, Gabrielle van Ramshorst, Ismaïl, Lawani, Anis, Cerovac, Samir, Delibegovic, Gustavo Mendonça Ataíde Gomes, Igor Lima Buarque, Muhammad, Gohar, Mihail, Slavchev, Chukwuemeka, Nwegbu, Arnav, Agarwal, Janet, Martin, Joshua, Ng-Kamstra, Maricarmen, Olivos, Wenhui, Lou, Dong-Lin, Ren, Jose Andres Calvache, Carlos, J Perez Rivera, Ana Danic Hadzibegovic, Tomislav, Kopjar, Jakov, Mihanovic, Pablo Mijahil Avilés Jiménez, Nikolaos, Gouvas, Jaroslav, Klat, René, Novysedlák, Nicolas, Amisi, Peter, Christensen, Alaa, El-Hussuna, Sylvia, Batista, Eddy, Lincango-Naranjo, Sameh, Emile, Danilo Alfonso Arévalo Sandoval, Hailu, Dhufera, Samuel, Hailu, Mengistu, G Mengesha, Joonas, H Kauppila, Alexis, P Arnaud, Zaza, Demetrashvili, Markus, Albertsmeier, Hans, Lederhuber, Markus, W Löffler, Daniel Kwesi Acquah, Bernard, Ofori, Stephen, Tabiri, Symeon, Metallidis, Georgios, Tsoulfas, Maria-Lorena, Aguilera-Arevalo, Gustavo, Recinos, Tamás, Mersich, Dániel, Wettstein, Gabriele, Kembuan, Peiman Brouki Milan, Mohammad Hossein Khosravi, Masoud, Mozafari, Ahmed, Hilmi, Helen, Mohan, Oded, Zmora, Gaetano, Gallo, Francesco, Pata, Gianluca, Pellino, Yuki, Fujimoto, Naoto, Kuroda, Mohamad, K Abou Chaar, Faris, Ayasra, Ildar, Fakhradiyev, Intisar Hisham Said Hamdun, Jang, Jin-Young, Mohammad, Jamal, Lina, Karout, Aiste, Gulla, Fanjandrainy, Rasoaherinomenjanahary, Luc Hervé Samison, Iran Irani Durán Sánchez, Diana Samantha Gonzalez, Laura, Martinez, María José Martínez, Alejandra, Nayen, Antonio Ramos-De la Medina, Jade, Nunez, Pueya Rashid Nashidengo, Rakesh, Shah, Ashish Lal Shrestha, Pascal, Jonker, Schelto, Kruijff, Milou, Noltes, Pieter, Steinkamp, Deborah, Wright, Lukman, Abdur-Rahman, Adesoji, Ademuyiwa, Adewale, Adisa, Babatunde, Osinaike, Justina, Seyi-Olajide, Omolara, Williams, Emmanuel, Williams, Sofija, Pejkova, Zainab Al Balushi, Raza, Sayyed, Mustafa Abo Mohsen, Sadi, A Abukhalaf, Moises, Cukier, Hugo, Gomez-Fernandez, Sebastian Shu Yip, Ximena Paola Vasquez Ojeda, Marie Dione Sacdalan, Piotr, Major, José, Azevedo, Miguel, F Cunha, Ahmad, Zarour, Eduard-Alexandru, Bonci, Ionut, Negoi, Sergey, Efetov, Viktor, Kochetkov, Andrey, Litvin, Jc Allen Ingabire, Georges, Bucyibaruta, Ntirenganya, Faustin, Sosthene, Habumuremyi, Alphonsine, Imanishimwe, Haragirimana Jean de Dieu, Emmanuel, Munyaneza, Isaie, Ncogoza, Abdourahmane, Ndong, Dejan, Radenkovic, Min Hoe Chew, Frederick, Koh, James, Ngu, Arpád, Panyko, Uros, Bele, Jurij Aleš Košir, Hassan, Daoud, Ana Maria Minaya Bravo, Umesh, Jayarajah, Dakshitha, Wickramasinghe, Mohammed Elmujtba Adam Essa Adam, Martin, Rutegård, Malin, Sund, Michel, Adamina, Eleftherios, Gialamas, Karoline, Horisberger, Muhammad, Alshaar, Abel, Huang, Varut, Lohsiriwat, Shane, Charles, Haithem, Jlassi, Arda, Isik, Hervé Monka Lekuya, Slava, Kopetskyi, Hayder, Alsaadi, Sattar, Alshryda, Osaid, Alser, Brittany, Bankhead-Kendall, Kerry, Breen, Hassan, Mashbari, Fernando Bonilla Cal, Hamza, Al-Naggar, Mayaba, Maimbo, Dennis, Mazingi, Tom, Abbott, Melika, Akhbari, Ruth, Benson, Shivam, Bhanderi, Bruce, Biccard, Edward, Caruana, Sohini, Chakrabortee, Reema, Chapatwala, Ainhoa, Costas-Chavarri, Andreas, K Demetriades, Anant, Desai, Salomone Di Saverio, Thomas, Drake, John, Edwards, Jonathan, Evans, Marco, Fiore, Samuel, Ford, Christina, Fotopoulou, Alexander, Fowler, Kaori, Futaba, Ian, Ganly, Harelimana Grace James, Ewen, Griffiths, Alessandro, Gronchi, Peter, Hutchinson, Gabriella Yael Hyman, Joseph, Incorvia, Ritu, Jain, Michael, Jenkinson, Tabassum, Khan, Stephen Richard Knight, Angelos, Kolias, Søren, Kudsk-Iversen, Tsun Yu Kwan, Elaine, Leung, Julio, Mayol, Siobhan, Mckay, John, G Meara, Emily, Mills, Susan, Moug, Akshay, Patel, Roberto, Perinotti, Henry, E Rice, Keith, Roberts, Andrew, Schache, Richard, Shaw, Neil, Smart, Matthew, Stephens, Grant, D Stewart, Ella, Teasdale, Peter, Vaughan-Shaw, Raghavan, Vidya, Naomi, Wright, Natalie, Zimmelman, Ervis, Agastra, Dariel, Thereska, Sergio Martin Lucchini, Veronica, Laudani, Carina, Chwat, Ivana Ines Pedraza Salazar, Diana Alejandra Pantoja Pachajoa, Agustin, Duro, José Alfredo Calderón Arancibia, Giuliana, D'Aulerio, Nagendra, Dudi-Venkata, Natasha, Egoroff, Shebani, Farik, Natalie, Lott, Jana-Lee, Moss, Sarah, Rennie, Lorwai, Tan, Uyen Giao Vo, David, Watson, David, Watters, Tim, Bright, Paul, Hollington, Xuanyu, Zhou, Hidde, M Kroon, Anthony, Farfus, John, Barker, Eleanor, Watson, Sean, Stevens, Haider, Latif, Amanda Caroline Dawson, Alwin, Chuan, Vijayaragavan, Muralidharan, Enoch, Wong, Travis, Ackermann, Maurizio, Pacilli, Russell, Hodgson, Alexander, Heriot, Peter, Choong, Wendy, Brown, Surjit, Lidder, Justin, Yeung, Luke, Traeger, Guillermo, Regalo, Ralph, Gourlay, Sarit, Badiani, Cherry, Koh, Soni, Putnis, Fayza, Haider, Ashrarur Rahman Mitul, Niels, Komen, Bert, Dhondt, Serge, Cappeliez, Manon, Pigeolet, Martijn, Schoneveld, Jasper, Stijns, Wouter, Oosterlinck, Nicolas, Flamey, Cyrille, Kpangon, Mouhamed, Agbadebo, Sèmèvo Romaric Tobome, Aldo Vieira Barros, Samuel Aguiar Júnior, Heloisa Galvão do Amaral Campos, Jefferson, Gross, Felipe José Fernandez Coimbra, Luiz Paulo Kowalski, Fabiana, Makdissi, Suely, Nakagawa, Joao Pedreira Duprat Neto, Jose Guilherme Vartanian, Guilherme, Yazbek, Stenio, C Zequi, Ronald, Flumignan, Natalia, Jaworska, Angela, Dell, Harsha, Shanthanna, Abdollah, Behzadi, Carolyn, Nessim, Michelle, Mozel, Pascal, St-Germain, Crispin, Russell, Gary, Groot, Najib, Safieddine, Duminda, Wijeysundera, Antoine, Eskander, Sami, Chadi, Shawn, Mackenzie, Alana, Flexman, Fernando, Heredia, Julio, Villanueva, Sofia, Waissbluth, Roberto, Macchiavello, Mario, I Escudero, Tyare, Fuentes, Ximena, Mimica, Dinimo Bolivar Saenz, Lina, Caicedo, Juan Pablo Alzate, Joaquin, Luna, Nestor Fabian Pedraza Alonso, Camilo Ortiz Silva, Juliana, Rodriguez, Liliana, Silva-Igua, Martha Luz Torres, Lina María Trujillo, Albaro José Nieto Calvache, Julián, Balanta-Melo, Rafael, Figueroa-Casanova, Oscar-Julián, García-Montoya, Carlos Andres Marulanda Toro, Marcela Velez Botero, Maria Clara Mendoza Arango, Eneida Diaz Martinez, Valentina Gutiérrez Perdomo, Emileth, Montenegro, Julia, Rodriguez-Abreu, Dolores, Mejía, Galal, Abouelnagah, Sameh, Shehata, Ahmed Hossam Eldin Fouad Rida, Ramy, A Hassan, Mahmoud, M Saad, Mohamed Reda Loaloa, Badr, Mostafa, Mohamed, Qassem, Mohamed, Fahmy, Hesham, Abozied, Ahmed, Y Azzam, Sherief, Ghozy, Asser, Sallam, Ahmed, Shehta, Mohamed, Abdelkhalek, Rehab, Samaka, Amr, Morsy, Ahmed Elshawadfy Sherif, Abraham, Negussie, Tigist, Fisseha, Kibruyisfaw, Shumbash, Metasebia, Abebe, Seid Mohammed Yasin, Yemisirach Bizuneh Akililu, Abebe, Megersa, Teshome, Tefera, Melatework, Assefa, Bahru, Atnafu, Bereket, Tsegaye, Yoseph Solomon Bezabih, Silamlak, Sisay, Kebebe, Bekele, Moa, Jira, Habtamu, Derilo, Eyueal, 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Mohammed Shadrul Alam, Akm Khairul Basher, Shahnoor, Islam, M Nazmul Islam, S, Sabbir, Karim, Muntasir, Faisel, Sadia, Khan, Iftekhar Ibne Mannan, Nawshin, Nazia, Malissa, Bentham, Sasha, Corbin, Alex, Doyle, Asha, Eastmond, Amelia, Haynes, Margaret, O'Shea, Emil, Phillips, Keisha, Walkes, Evgeniy, L Artyushkov, Mark, L Kaplan, Vladislav, Straltsov, Yauheniya, Litvina, Alexei, Lyzikov, Victor, E Tihmanovich, Mafalda, Borges, Tim, Brits, Nicolas De Hous, Stefan De Wachter, Tomas, Menovsky, Xavier, Mortiers, Dorien, Vermeulen, Nils, Vleminckx, Dirk, Ysebaert, Julie, Bontinck, Danny, Bulthé, Ricky, Rasschaert, Anne-Sophie Van Haver, Koen Van Belle, Laurence, Verstraeten, Manon, Vounckx, Sébastien, D'Ulisse, Yasmine De Bruyne, Badih El Nakadi, Tessely, Heloise, Matteo, Luisetto, Sotirios, Marinakis, Maxime, Maton, Claire, Viste, Elke Van Daele, Mathieu, Vandeputte, Marc, Duinslaeger, Daniel, Jacobs-Tulleneers-Thevissen, Yanina, Jansen, Ward, Janssens, Rastislav, Kunda, Nouredin, Messaoudi, Michael, Ruyssers, Ellen Van Eetvelde, Marian, Vanhoeij, Jef Van den Eynde, Raf Van den Eynde, Ahmed, M Chaoui, Marcellin, Akpla, Souliath, Lawani, Hermann, Agossou, Hulrich Aouagbe Behanzin, Covalic, Bokossa, Hubert, Dewanon, Hugues, Yome, Alassan, Boukari, Oswald, Gbehade, Labissi Francois Amossou, Francis, Dossou, Tatjana, Barišić, Miran, Boras, Zdrinko, Brekalo, Ivana Čuljak Blagojević, Ana, Damjanović, Vedran, Dragisic, Ana Dugandžić Šimić, Filip, Gunaric, Martin, Kajic, Darko, Knežević, Tanja, Krešić, Valentina, Lasić, Ludvig, Letica, Vlatka, Martinovic, Iva, Mikulic, Josip, Miskovic, Hrvoje, Pehar, Pejana, Rastović, Irena, Sesar, Violeta, Šetka-Čuljak, Martina, Soljic, Dejan, Tiric, Vajdana, Tomić, Anja, Vasilj, Igor, Hudic, Renato Aguera Oliver, Felipe Azenha Lamonica, Jorge De Medeiros, Henrique Donizetti Bianchi Florindo, Rodolfo Jose Favaretto Filho, Fernanda Costa Pereira, Rodrigo, Rodrigues, Antonio Antunes Rodrigues Junior, Fernanda Ruiz de Andrade, Maisa, Salvetti, 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Juliana Sanchez, David Mauricio Solano Varela, Paula Torres Gomez, Marcial, Trillos, Ana María Vargas Patiño, Felipe, Vargas-Barato, Juan Pablo Villate Leon, María Alejandra Wagner Useche, Jesus, Acosta, Adriana, Almeciga, Luis Becerra Mendez, Rafael Jose Beltran, Ana, Bonilla, Miguel, Buitrago, Marino, Cabrera, Pedro Hernando Calderon Quiroz, Diego, Camacho-Nieto, Carlos Andrés Carvajal Fierro, Sergio Cervera Bonilla, Sandra, Diaz, Helena, Facundo, Jorge, Forero, Mauricio Garcia Mora, Karena Victoria Garcia Tirado, German Fabian Godoy Perez, Felipe, Gonzalez, Oscar, Guevara, Jairo Alonso Hernandez, David Ricardo Herrera Mora, Juan David Lalinde, Carlos, Lehmann, Eduardo Leon Llanos, Byron Eduardo Lopez De Mesa Lopez, Ivan, Mariño, Monica, Medina, Raúl Eduardo Pinilla Morales, Angela, Puerto, Andrea, Quintero-Ortíz, Juliana Rendón Hernández, Elio Fabio Sánchez Cortés, Alvaro Eduardo Sánchez Hernández, Raul, Suarez, Oscar, Suescun, Marco, Vanegas, Rodolfo, Varela, Jorge Luis Velez 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Alvarez, Cesar David Galindo Regino, Angela Maria Giraldo Velasquez, Carlos Enrique Melo Moreno, Jorman, H Tejada, Jesus Hernan Tovar, German Alirio Tovar, Edison Alexander Benavides Hernández, Claudia Milena Orozco-Chamorro, Gustavo Adolfo Angel, Christian Ali Buesaquillo, Victor David Olave Montaño, Andrés, Sánchez-Gómez, Daniela Patricia Escalante Ureche, Jairo Martinez Garrido, Eben-Ezer, Genda, Fabrice, Eboma, Kristina, Bitunjac, Karlo, Grulović, Marijana, Vučković, Goran, Šantak, Emanuel, Borovic, Ana Bosak Versic, Damir, Hasandić, Natasa Poldan Grabar, Suzana Srsen Medancic, Lucija, Brkic, Sara, Cokarić, Petra Pavic Palac, Zeljka, Samac, Josipa, Tomić, Marija, Vrdoljak, Ivan, Bacic, Bernarda, Bakmaz, Nikolina Bratošević Vučičić, Domagoj, Brzic, Samir, Canovic, Emilio, Dijan, Maja Grgec Dragicevic, Robert, Karlo, Suzana, Konjevoda, Petra, Kovačević, Ivan, Kovačić, Frane, Markulić, Luka, Matak, Domagoj, Morović, Gordan, Perišić, Andrea, Simic, Neven, Skitarelić, Matea, Veršić, 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Baelum, Mark Bremholm Ellebaek, Signe Bremholm Ellebaek, Anders, Hogh, Maria, Acosta, Yancy, Acosta, Pedro, Baez, Luis Alfredo Betances, Luis Rodolfo Bonilla, Daniel, Cabreja, Wilton Cabrera Cruz, María Mabel Collado Expósito, Aldo, Crespo, Octavio, Cruz-Pineda, Claudio Samuel D'óleo García, Pedro, Díaz, Remberto, Escoto, Jatnna, Figueroa, Luis, Garcia, U Garcia-Dubus Rodriguez, Humberto, Gomez, Adrian, Grullon, Fatherin, Guerrero, Lillian, Guzman, Thelma Rocío Jiménez Mosquea, Engels, Lazala, Ariela, Lopez, Leeany Maletta Francisco, Jhomayri, Mercado, Herisardy, Munoz, Jeffrey, Paulino, Maricely Ambar Perez Fernandez, Rudeily, Reyes, Lilia Rosa Reyes Guilamo, Ruben, Rivas, Claudia Alejandra Rivas Torres, Ada, Rodríguez, Madelin Tamar Rosario Villa, Eleazar, Santana, Joel, Soto, Nassin, Tactuk, Cristina Kristel Tonos Sardiñas, Raul, Ubinas, Jose, Victoria, Aaron, Villegas, Ricardo, Acra-Tolari, Larissa, Beltran, Luis Fernand Betances, Alejandro, Blaubach, Denisse Idalia Campos Mejía, Nathalia, Capellan, María Fernanda Cedeño Bruzual, Saray Cordero Spencer, Gabriella Cuevas Lantigua, Luis De Jesus, Gabriela, Díaz, Pedro Pablo Díaz Vásquez, Karla, Disla, Jesús Antonio Echavarría Uceta, Paola Irina Eusebio Jimenez, Damaris, Fernandez, Marlin Fernandez Camilo, Jiomar Manuel Figueroa Germosen, Maruel, Fortunato, Leyla Gabriel Fernández, Alicia German Dihmes, Héctor, Herrera, Elizabeth Leon Cuevas, Jose Alejandro Mata, Mirian Mateo De La Cruz, Dolores Mejia De la Cruz, Marcos, Mirambeaux, Fabio Ortiz De La Cruz, Henry, Paulino, Gabriela, Pelletier, Merycarla, Pichardo, Rodriguez Pumarol Próspero Enrique, Julio, Rivas, Ann Stephany Sanchez Marmolejos, Roman Santana Santana, Irina Suero Almanzar, María Magdalena Vásquez Sánchez, Nicolás, Campuzano, José Ricardo Negrete Ocampo, Maria, Armas, Alvaro Santiago LeMarie Guerra, Gustavo León Vizcaya, Omar Ahmed Abdelwahab, Ahmed, O Elmehrath, Mohammed Ezzat Mostafa, Gamal, Amira, Ibrahim, Sallam, Mohamed, Sherief, Ahmed, 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Maher, Hosain, Ahmed, Hossam, Hamza Hussein Aly Salama Aly, Mohamed, Ibrahim, Abdelrahman, Ibrahim, Nourhan, Ibrahim, Noha Mohamed Salah Ibrahim Moussa Hamouda, Monica, Iskander, Islam, Khalifa, Mostafa, Kotb, Nada, Mahmoud, Alaa Mahmoud Abo Shabana, Nora, Mamdouh, Maram, Metwalli, Khaled, Metwally, Mahmoud, Moghazy, Moustafa, Mohamed, Mohamed, Mourad, Esraa, Moustafa, Kamilia, Mubarek, Nour Eldin Nader, Ahmed, Nasser, Samaa, Omar, Mostafa Shehata Qatora, Mohamed, Ragab, Marawan, Ragal, Dina, Ramadan, Rana, Ramadan, Sara, Ramadan, John, Romany, Ahmed, Sabry, Yasmeen, Said, Sara, Salamah, Ahmed Mostafa Saleh, Mona Saleh Mesbah Mohamed Elkaffas, Alaa, Salem, Hashem, Salim, Ahmed, Samih, Ahmed Samir Abdelaal, Ahmed, Shaheen, Yassmeen Sharafeldin Mohammed, Abdelrahman, Shehata, Mohamed, Shemeis, Karim, Shenit, Mennatallah, Sheta, Asmaa, Soffar, Yousef, Tanas, Ahmed, Tarek, Nermin, Yehia, Omar Khaled Mohamed Eid, Ammar Yasser Abdulfattah, Ahmed, Elsaghir, Mohamed Fouad Elganainy, Omar Ibrahim Elsayed, Omar, Elmandouh, Omar, Hamam, Mostafa Ahmed Shehata, Areej, A Abdelaziz, Ahmed, M Abbas, Wael Abd El-Ghani, Hossam Aldein, S Abd Elazeem, Mustafa Abd Elsayed, Ahmed Yassien Abd-Elkariem, Shimaa, Abdalla, Mahmoud, Abdel-Aleem, Khaled, Abdelazeem, Mahmoud, Abdelfattah, Mohammed, Abdelhafez, Mohamed, M Abdelkarem, Ali, Abdelraouf, Lamess, Abdullaha, Hossam, Abubeih, Moaiad Eldin Ahmed, Nagm Eldin Abu Elnga Ahmed, Ahmed, Ahmed, Sarah Ahmed Saad, Sherif, Alaa, Ali, Alhussaini, Abdelrahman Ahmed Abdelrahman Ali, Ibrahim, Ali, Wagdi, Ali, Mohamed Ali Mohamed, Mohamed, Ashraf, Muhammad, Bassiouni, Mohamed, G El-Adawy, Mohammad, El-Sharkawi, Hussein, Elkhayat, Khaled, Elmaghraby, Shady, Elsdfy, Mohamed, Elsharkawy, Almoutaz, Eltayeb, Mohamed Esmat Mohamed, Esraa, Essam, Mahmoud, Fahd, Osama, Farouk, Rabea, Gadelkareem, Ahmed, Ghoneim, Mohammed Hamada Takrouney, Ahmed, Hamdan, Abd El-Rahman Hamed, Ahmad, Hasan, Mohamed Abdelghafor Hassanin, Islam, Hawal, Kerollos, Henes, Mohamed Omar Herdan, Helal, F Hetta, Omar, Ibrahem, Mostafa, Ibrahim, Islam, H Ibrahim, Mahmoud, Kamel, Mohamed, Khallaf, Shrouk, M Elghazaly, Abobakr, Mahfouz, Osman, Mahmoud, Wesam, Mahran, Doha, Mahrous, Abadeer, Marsis, Ayman, Mohamed, Aliae Mohamed Hussein, Amr Mohamed Sayed, Mahmoud, M Mohammed, Ahmed, Mokhtar, Fatma, A Monib, Ahmed, Nageeb, Mariam Albatoul Nageh, Mohammed, Nageh, Nehal Gamal Omar, Abdelrahman, Ragab, Abdelrahman, Ramadan, Abdallah Rashad Temerik, Aya, Sabry, Hadeer, Safwat, Omar, Salah, Ahmed Elhussiny Salah Mahmoud, Ahmed, Saleh, Mahmoud, Sallam, Ahmed, Samir, Reem, Sayad, Esraa, Sayed, Ahmed, S Sedik, Mohammed, Shahine, Antonios, Soliman, Wael, Soliman, Mohamed Gamal Taher, Randa, Wanees, Ebrahim Ahmed Yousof, Ahmed, Youssef, Omar Zein Elabedeen, Ahmed Emad Sayed Hassan, Shrouk Abdel Fattah, Ahmed, Abostate, Samar, Ali, Saad Ali Saad Salama, Mohamed, Allam, Ahmed, Alsadek, Ebrahim, Arafa, Ahmed, Barakat, Mohammed El Sherpiny, Gehad, Elbehairy, Mahmoud, Eleisawy, 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Krause, Frank, Meyer, Salmai, Turial, Bilal, Al-Nawas, Marco Johannes Battista, Jan, Goedeke, Annette, Hasenburg, Julia, Heider, Lena Katharina Mueller, Simon, Zeller, Sina Louisa Patrizia Jentschura, Karl-Friedrich, Kowalewski, Maximilian, Kriegmair, David, Männle, Christoph, Reissfelder, Nicole, Rotter, Claudia, Scherl, Steffen, Seyfried, Andreas, Kirschniak, Jens, Rolinger, Peter, Wilhelm, Franz, G Bader, Stephanie, Ottl, Alexandra Viktoria Behr, Alexandros, Diamantis, Andreas, Fichter, Florian, Grill, Matthias, Heck, Daniel, Jira, Michael, Kallmayer, Florestan, Koll, Stefan, Luhne, Bernhard, Meyer, Robert, Patachia, Ilaria, Pergolini, Seyer, Safi, Christoph, Schäffer, Moritz, Schirren, Helmut, Wegmann, Markus, Wirth, Zhaojun, Zhu, Ughur, Aghamaliyev, Mahmoud, Almaghrabi, Wolfgang, Böcker, Jan, Bruder, Konstantin, Frank, Viktoria, Herterich, Verena, Huber, Matthias, Ilmer, Christian, Kammerlander, Carl, Neuerburg, Viktor, H von Ehrlich-Treuenstätt, Jens, Werner, Nikolaus, Börner, 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Massimiliano, Gennaro, Lorenzo, Giannini, Marcello, Guaglio, Marco, Guzzo, Andrea, Leva, Alberto, Macchi, Elena, Manzo, Fabio, Martinelli, Ilaria, Mattavelli, Vincenzo Maria Mazzaferro, Francesco, Raspagliesi, Luigi, Rolli, Laura, Sala, Roberto, Salvioni, Mario, Santinami, Silvia, Segattini, Luca, Sorrentino, Carlotta, Zaborra, Alexandre, Anesi, Gianmaria Casoni Pattacini, Mattia Di Bartolomeo, Francesca, Pecchini, Arrigo, Pellacani, Micaela, Piccoli, Federico, Fusini, Andrea, Gattolin, Marco, Migliore, Roberto, Rimonda, Diego, Sasia, Elisabetta, Travaglio, Federica, Brunetti, Marco, Cereda, Marco, Ceresoli, Luca, Cigagna, Cristina, Dell'Oro, Alessandro, Fogliati, Robert, Fruscio, Tommaso, Grassi, Maini Marzia Isabella, Luca Carlo Nespoli, Massimo, Oldani, Sara, Ornaghi, Nicolò, Tamini, Carmine, Antropoli, Antonio, Castaldi, Alessio, Palumbo, Gaia, Altieri, Umberto, Bracale, Francesco, Corcione, Marcello De Luca, Giovanni Domenico De Palma, Maria Michela Di Nuzzo, Ruggero, Lionetti, 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Matteo, Filardo, Marika Sharmayne Milani, Franco, Ragni, Andrea de Manzoni Garberini, Edoardo, Baldini, Diana, Carpaneto, Michele, Cauteruccio, Corrado, Ciatti, Luigi, Conti, Serena, Gattoni, Pietro, Maniscalco, Gerardo, Palmieri, Calogero Puma Pagliarello, Giuseppe, Caristo, Raffaele, Galleano, Michele, Malerba, Marcello, Calabrò, Francesca, Farnesi, Elia Giuseppe Lunghi, Andrea, Muratore, Nicoletta Sveva Pipitone Federico, Joel Reuben Abel, Lorenzo, Andreani, Darienzo, Antonio, Vittorio, Aprile, Riccardo, Balestri, Giacomo, Benettini, Stefano, Berrettini, Luca, Bruschini, Massimo, Chiarugi, Federico, Coccolini, Simone, Colangeli, Camilla, Cremonini, Lodovica Cristofani Mencacci, Iacopo, Dallan, Silvia De Santi, Gregorio Di Franco, Lorena Di Girolami, Giacomo, Fiacchini, Niccolò, Furbetta, Stylianos, Korasidis, Marco, Lucchi, Andrea, Morandi, Luca, Morelli, Serena, Musetti, Carlo Maria Neri, Matteo, Palmeri, Miriana, Picariello, Francesco, Porcelli, Marco, Puccini, Nicolo, Roffi, Erica, Statuti, Dario, Tartaglia, Alberto, Tonelli, Matteo, Vianini, Gianluca, Baronio, Mauro, Montuori, Enrico, Pinotti, Stefano Maria Massimiliano Basso, Federica, Maffeis, Paolo, Ubiali, Lorenzo, Aguzzoli, Saverio, Coiro, Giuseppe, Falco, Vincenzo Dario Mandato, Valentina, Mastrofilippo, Simone, Mele, Caterina, Baldi, Carlo, Corbellini, Gianluca Matteo Sampietro, Massimo, Dugo, Mauro, Garino, Chiara, Marafante, Antonio, Masciandaro, Elisabetta, Moggia, Alessandra, Murgese, Felice Eugenio Agro, Gabriella Teresa Capolupo, Filippo, Carannante, Marco, Caricato, Vincenzo, Denaro, Erica, Mazzotta, Rocco, Papalia, Giuseppe, Pascarella, Alessandro, Strumia, Biagio, Zampogna, Matteo, Cinquepalmi, Marco, Colasanti, Celeste Del Basso, Federica, Falaschi, Nicola, Guglielmo, Roberto Luca Meniconi, Alessandra, Pecoraro, Sofia, Usai, Giacomo, Crescentini, Antonella, Larcinese, Emanuele, Picone, Giovanni, Sinibaldi, Annamaria, Agnes, Salvatore, Agnes, Sergio, Alfieri, Francesco, Belia, Valentina, Bianchi, Giuseppe, Bianco, Alberto, Biondi, Paola, Campennì, Valerio, Cozza, Sabatino, D'Archi, Domenico, D'Ugo, Veronica De Simone, Marta Di Grezia, Sofia Di Lorenzo, Federica, Ferracci, Valeria, Fico, Gianluca, Franceschini, Pietro, Fransvea, Giulio, Gasparini, Luca, Gordini, Antonio La Greca, Francesco, Litta, Celestino Pio Lombardi, Angelo Alessandro Marra, Angelo, Parello, Marco Maria Pascale, Romeo, Patini, Gilda, Pepe, Roberto, Persiani, Caterina, Puccioni, Carlo, Ratto, Fausto, Rosa, Gianmarco, Saponaro, Lorenzo, Scardina, Tedesco, Silvia, Giuseppe, Tropeano, Maria, Benevolo, Daniele, Bugada, Flaminia, Campo, Maria Gabriella Dona, Valentina, Manciocco, Paolo, Marchesi, Riccardo, Mastroianni, Francesco, Mazzola, Silvia, Moretto, Raul, Pellini, Gerardo, Petruzzi, Barbara, Pichi, Giuseppe, Simone, Gabriele, Tuderti, Jacopo, Zocchi, Luigi Marino Cosentino, Andrea, Sagnotta, Roberta, Angelico, Vittoria, Bellato, Michela, Campanelli, Marzia, Franceschilli, Michele, Grande, Giorgio, Lisi, Tommaso Maria Manzia, Lorenzo, Petagna, Bruno, Sensi, Giuseppe, Sica, Leandro, Siragusa, Giuseppe, Tisone, Marco, Assenza, Barbara, Binda, Massimo, Biondi, Gioia, Brachini, Placido, Bruzzaniti, Mauro, Casagrande, Flavia, Ciccarone, Pierfranco Maria Cicerchia, Bruno, Cirillo, Daniele, Crocetti, Giancarlo, D'Ambrosio, Vito, D'Andrea, Francesca De Felice, Giorgio De Toma, Carlo Della Rocca, Giulia, Duranti, Pietro, Familiari, Enrico, Fiori, Giovanni Battista Fonsi, Alessandro, Frati, Stefania La Rocca, Filippo La Torre, Pierfrancesco, Lapolla, Giovanni, Marruzzo, Simona, Meneghini, Andrea, Mingoli, Andrea, Picchetto, Antonella, Polimeni, Diego, Ribuffo, Maurizio, Salvati, Antonio, Santoro, Paolo, Sapienza, Luigi, Simonelli, Valentino, Valentini, Martina, Zambon, Giuseppa, Zancana, Emma, Zuppi, Simone, D'Annunzio, Cosimo De Nunzio, Silvia, Fiorelli, Mohsen, Ibrahim, Chiara, Loffredo, Domenico, Massullo, Cecilia, Menna, Rocco, Monica, Massimiliano, Pelli, Erino Angelo Rendina, Leonardo, Teodonio, Andrea, Tubaro, Giulio, Argenio, Giulio, Accarino, Accarino, Giancarlo, Antonio Nicola Giordano, Luca, Cardinali, Elisa, Sebastiani, Grazia, Travaglini, Erika, Andreatta, Emanuele Luigi Giuseppe Asti, Daniele, Bernardi, Luigi, Bonavina, Caterina, Froiio, Andrea, Lovece, Chiara, Copelli, Alfonso, Manfuso, Pasquale Di Maio, Marco, Giudice, Oreste, Iocca, Rosario, Cennamo, Tommaso, Cornali, Francesco Di Marzo, Cristian, Altana, Francesco, Bussu, Giampiero, Capobianco, Anna Giacomina Carta, Sandro, Ciccarello, Maria Laura Cossu, Pietrina, Cottu, Giacomo De Riu, Salvatore, Dessole, Francesco, Dessole, Salvatora, Dettori, Carlo, Doria, Alessandro, Fancellu, Claudio, F Feo, Giorgio Carlo Ginesu, Giuliana, Giuliani, Marco Giuseppe Iannuccelli, Massimo, Madonia, Roberto, Mancino, Olindo, Massarelli, Gianfranco, Meloni, Fabio, Milia, Andrea, Mulliri, Teresa, Perra, Marco, Petrillo, Antonio, Piras, Franco, Piredda, Francesco, Pisanu, Alberto, Porcu, Davide, Rizzo, Angelino, Sanna, Antonio Mario Scanu, Fabrizio, Scognamillo, Damiano, Soma, Anna Rita Tanca, Alessandro, Tedde, Matteo, Tedde, Luigi Angelo Vaira, Andrea Bartalini Cinughi de Pazzi, Osvaldo Carpineto Samorani, Daniele, Fusario, Luigi, Marano, Gaia, Oldrà, Anna Lisa Pesce, Stefania Angela Piccioni, Luca, Resca, Vincenzo, Ricchiuti, Franco, Roviello, Vinno, Savelli, Alberto, Abrate, Pierpaolo, Bordoni, Lorenzo, Bosio, Guglielmo, Clarizia, Francesco, Fleres, Marco, Franzini, Antonio, Fratto, Pierluigi, Giumelli, Alessandro, Grechi, Alessandro, Longhini, Fabrizio, Lorusso, Elisa, Scarnecchia, Federica, Scolari, Alessandro, Spolini, Vincenzo, Maiuri, Matteo, Papandrea, Arturo, Roncone, Lorenzo, Conti, Andrea, Rizzi, Marco, Rovagnati, Alberto, Brolese, Tommaso, Cai, Francesco Antonio Ciarleglio, Francesca, Dalprà, Gianni, Malossini, Liliana, Mereu, Irene, Tamanini, Saverio, Tateo, Giovanni, Viel, Enrico, Battistella, Paolo Boscolo Rizzo, Cristoforo, Fabbris, Marco, Massani, Giacomo, Spinato, Roberta, Tutino, Ugo, Grossi, Alessandro, Iacomino, Simone, Novello, Maurizio, Romano, Serena, Rossi, Giulio, Santoro, Giacomo, Zanus, Sokol, Trungu, Giada, Aizza, Gabriele, Bellio, Selene, Bogoni, Marina, Bortul, Biagio, Casagranda, Sara, Cortinovis, Nicolò de Manzini, Davide, Drigo, Paola, Germani, Manuela, Mastronardi, Lucia, Paiano, Silvia, Palmisano, Pier Luigi Filosso, Francesco, Guerrera, Matteo, Marro, Mauro, Rinaldi, Enrico, Ruffini, Stefano, Salizzoni, Laura, Bardelli, Mattia, Berselli, Giacomo, Borroni, Eugenio, Cocozza, Matteo, Desio, Bottazzoli, Elisa, Giuseppe, Ietto, Valentina, Iori, Domenico, Iovino, Lorenzo, Livraghi, Valentina, Marchionini, Stefano, Megna, Emma Amal Nahal, Mara, Palumbo, Valeria, Quintodei, Alessandra, Zullo, Lucrezia, D'Alimonte, Giovanni, Pirozzolo, Chiara, Vignotto, Tommaso, Campagnaro, Andrea, Caravati, Simone, Conci, Carlotta De Cristofaro, Gabriele, Gecchele, Tommaso, Giuliani, Jacopo, Graziosi, Alfredo, Guglielmi, Salvatore, Paiella, Corrado, Pedrazzani, Tommaso, Pollini, Simone, Rattizzato, Andrea, Ruzzenente, Roberto, Salvia, Giulia, Turri, Matilde, Bacchion, Giovanni, Butturini, Andrea, Casaril, Alessandro, Giardino, Harmony, Impellizzeri, Marco, Inama, Frigerio, Isabella, Gianluigi, Moretto, Marco De Zuanni, Enrica, Deiana, Mario, Guglielmo, Alessandro, Broglia, Claudia, Casarini, Caterina Costanza Zingaretti, Marta, Bonaldi, Giovanni, Cesana, Francesco, Mastriale, Stefano, Olmi, Matteo Uccelli Yasuyuki Fukami, Takuya, Saito, Tsuyoshi, Sano, Naoki, Hirai, Kazuyoshi, Hirota, Tetsuya, Kushikata, Tasuku, Oyama, Junichi, Saito, Katsuhiko, Ishibashi, Mizue, Kamiyama, Kyongsuk, Son, Kentaroh, Tarao, Takayuki, Yamada, Toshiya, Shiga, Chisaki, Aze, Yoshihiko, Deguchi, Hirotoshi, Hasegawa, Tatsuki, Hoshino, Yasushi, Innami, Hiroyuki, Inoue, Shingo, Ito, Takeshi, Nomura, Tomomi, Ogihara, Reina, Okada, Takashi, Ouchi, Yuri, Sekiya, Keikoku, Tachibana, Emi, Takano, Masae, Yamamoto, Shuko, Matsuda, Yuka, Matsuki, Kenji, Shigemi, Teruyuki, Hiraki, Yui, Inoue, Shosaburo, Jotaki, Tatsuro, Abe, Masatoshi, Eto, Junichi, Inokuchi, Eiji, Kashiwagi, Fumio, Kinoshita, Satoshi, Kobayashi, Ken, Lee, Takashi, Matsumoto, Keisuke, Monji, Hidekazu, Naganuma, Masaki, Shiota, Ario, Takeuchi, Shinju, Obara, Saori, Takatsuki, Saori, Tanaka, Koji, Iida, Kota, Kagawa, Shuichiro, Neshige, Tomohiro, Chaki, Naoyuki, Hirata, Satoshi, Kazuma, Motonobu, Kimizuka, Sho, Kumita, Noriaki, Nishihara, Sato, Satoshi, Atsushi, Sawada, Shunsuke, Tachibana, Michiaki, Yamakage, Yuta, Nakamura, Kozo, Sato, Tomoya, Irie, Tomoko, Irisawa, Eiki, Kanemaru, Yuko, Koga, Yoshihiko, Chiba, Jun, Makino, Shinnosuke, Ohama, Shinichiro, Okada, Kano, Teruaki, Tatsuya, Kida, Tomohide, Takei, Kazuhiro, Hanazaki, Hiroyuki, Kitagawa, Tsutomu, Namikawa, Toshiyuki, Mizota, Chikashi, Takeda, Shintaro, Yagi, Hiroshi, Imai, Makoto, Ishitobi, Manabu, Kato, Kouhei, Nishikawa, Takeshi, Sasaki, Hiroshi, Yonekura, Akihiro, Kanaya, Daisuke, Irimada, Haruka, Ishikawa, Kaiho, 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Mubaydeen, Husam, Sarayrah, Mohammad Abdel Elah, A Tarawneh, Mohammad Yousef Karasneh, Amany, Zurgan, Mohammad, Alassaf, Sayel, H Alzraikat, Justin, Z Amarin, Ahmed, Hijjawi, Haya, H Suradi, Louay, Y Zaghlol, Ahmad, Abdalah, Ghaida, Abdallah, Ammar Abu Tarieh, Tareq, Abu-Libdeh, Faisal, Abualteen, Murad Al Abdallah, Zakaria Al Bdour, Seif Al Dahabrh, Farah, Al-Kasaji, Zaid Al-Sheikh Ali, Mohammad, Al-Thaher, Tareq, Alnajjar, Mohannad, Alqedrh, Mohammad, Alsaleh, Mohammad, Alzaatreh, Ghandi, Amayreh, Yazeed, Ayasra, Ahmad, Eid, Ibrahim, Ghayada, Khaled Moh'd Ahmed Hasanein, Anas, Hassouneh, Raid, Hijazeen, Majedah, Hmeidan, Ahmed, Khaled, Barihan, Khasawneh, Omar, Kifayeh, Yasser, Lafi, Jasem, Seba, Qusai, Semrin, Fda, Sma, Mohammad, Theab, Haitham, Tumeh, Muna Aba Zaid, Alaa, Abazeed, Bader, Abbad, Osaid, Abbadi, Nizar, Abu-Ishkerih, Malk, Al-Osta, Reham, Al-Zyadat, Bashar Omar Falah Alawneh, Majd, Alhattab, Mohd Mujahed Alkurdieh, Ziad, Awwad, Mohammad, Hammouri, Hamzeh, Hussein, 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Alameen, Rehab, Alarabi, Alarabi, Alarabi, Aisha, Alelwany, Abdulkarim, Alesmail, Noran, Algadi, Khuloud, Almaqrahi, Hadel, Alosta, Mohamed, Alsharedi, Rasha, Bashir, Mahmoud Ben Ghrema, Sari Bin Nour, Sofian, Elbarouni, Ahmed, Elhadi, Abdulmohimen, A Elkhadar, Esraa, Elkouba, Nabiha, Elmsherghi, Abdulmohimen, Gammoudi, Abdulraouf, Ghariba, Fatima Zayed Gjam, Arwa, Haidar, Hala, Helal, Mohammed, Huwaysh, Ahmed Khalid Alhadheeri, Eslam, Kriem, Halim, Osman, Mohamed Ali Ossman, Marwah, Shilfeet, Laila, Turshani, Nouran, Albishty, Abdulmueti, Alhadi, Salem, Ali, Manal Ahmed Altoumi, Sumayyah Ghayth Bahroun, Eman, Younes, Hana, Atarabulsi, Mohamed, Elshaibi, Abdullmujeeb, Othman, Hayat Ben Hasan, Najat Shaban Ben Hasan, Rabab Shaban Ben Hasan, Vidmantas, Barauskas, Edvinas, Dainius, Zilvinas, Dambrauskas, Albertas, Dauksa, Inga, Dekeryte, Rita, Gudaityte, Kristijonas, Jasaitis, Akvilė, Koženiauskaitė, Virgilijus, Krasauskas, Ausra, Lukosiute-Urboniene, Almantas, Maleckas, Romualdas, 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Rakotoarisoa, Maharo, Ramifehiarivo, Solonirina Harinarindra Ranaivoson, Hajamihamina Marina Parfaite Randriantsoa, Narindra Njarasoa Mihaja Razafimanjato, Jeannie Ba Razafindrahita, Solofoarimanana, Solofoarimanana, Guillaume Odilon Tsiambanizafy, Rakotonaivo Mamisoa Judicaël, Corinne Eulalie Solo, Tojomamy Herinjaka Ralaizafindraibe, Fanonjomahasoa Safiry Andofenohasina, Hanta, Rasataharifetra, Vanona Barijaona Razafindraibe, Angelin Sablon Herinirina, Andre, Das, Thanga, Ganapathy, Yohesuwary, Gunarasa, Kalyani, Mariapan, Maathichsudhaar, Muniandy, Mohd Firdauss Osman, Mohd Azem Fathi Mohammad Azmi, Jien Yen Soh, Wan Zainira Wan Zain, Andee Dzulkarnaen Zakaria, Zaidi, Zakaria, Kheng Hooi Chan, Firdaus, Hayati, Syamim, Johan, Jin Jiun Mah, Ratha Krishnan Sriram, Sentilnathan, Subramaniam, Nur Shahirah Binti Muhammad Shahimi, Khairul Hazim Hamdan, Mohd Razali Ibrahim, Guhan, Muthkumaran, Ju Ann Tan, Mohana Raj Thanapal, Dayang Anita Abdul Aziz, Mae-Lynn, Bastion, Mohd Hairul Nizam 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Sainal, Mat Salleh Sarif, Richelle, Chua, Aini Fahriza Ibrahim, Abdul Rauf Bin Ahmad, Yii Ling Lau, Ka Yee Liew, Kandasami, Palayan, Hui Yu Wong, Jasiah, Zakaria, Nor Azimah Abd Aziz, Norazila Abdul Rahim, Noorneza Abdul Rahman, Bahiyah, Abdullah, Mohamed Faizal Bin Sikkandar, Fatin, Firman, Nik Mohd Hazleigh, Intan Kartika Kamarudin, Shahril, Khalid, Mohd Fairudz Mohd Miswan, Akmal Zulayla Mohd Zahid, Norasyikin, Mustafa, Kadhim, Obaid, Mohd Yusoff Bin Yahaya Yahaya, Ahmad Ramzi Yusoff, Predrag, Andrejevic, Jeremy Borg Myatt, Svetlana, Brincat, Clifford, Caruana, Kurt Lee Chircop, Francesca, Chircop, Daniel Mario Chircop, Charles, Cini, Viktoria, Czok, Melanie, Farrugia, Gabriella, Grima, Fatimah Mj Hassan Almukhariq, Esther, Muscat, Darryl, Pisani, Mohsin Hassan Khan Roshan, Nicholas, Schembri, Mohamed, Shoukry, Neville, Spiteri, Gilbert, Tanti, Ziad Aboharp Hasan, Alberto Bazan Soto, Cedillo Rodrìguez Jonathan Rubén, Gustavo Esteban Lugo Zamudio, David Gerardo Miranda Gómez, José 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Uros, Bumbasirevic, Zoran, Dzamic, Boris, Kajmaković, Bogomir, Milojevic, Nebojša, Prijović, Marko, Zivkovic, Aleksandar, Lazic, Nebojsa, Mitrovic, Dejan, Stevanovic, Marko, Buta, Ana, Cvetkovic, Igor, Djurisic, Merima, Goran, Zorka, Inic, Andjela, Ivezić, Nikola, Jeftic, Marko, Jevric, Vladimir, Jokic, Milan, Kocic, Zoran, Kozomara, Ivan, Markovic, Srdjan, Nikolic, Nada, Santrac, Nevena, Savković, Igor, Spurnic, Dobrica, Stevic, Dejan, Stojiljkovic, Jovana, Tripkovic, Nikola, Vucic, Milan, Zegarac, Tatjana, Dejanovic, Vladimir, Djukic, Srdjan, Marinković, Miljan, Milanovic, Nemanja, Pijanovic, Milena, Radosavljevic, Predrag, Savic, Dejan, Stojakov, Rastko, Živić, Sinisa, Ducic, Mikan, Lazovic, Jovana, Bojičić, Vladica, Cuk, Jovan, Juloski, Aleksandar, Karamarkovic, Marko, Kenic, Bojan, Kovacevic, Igor, Krdzic, Vladan, Milutinović, Vladimir, Djan, Velicko, Trajkovic, Dragana, Zivkovic, Aleksandar, Đermanović, Danica, Golijanin, Dejan, Lukic, Zoran, Radovanovic, Dragana, Radovanovic, Sanja, Zahorjanski, Adrian, Chiow, Jun Xian Hing, Lip Seng Lee, Sey Kiat Terence Lim, Chi Wei Mok, Su-Ming, Tan, Hiang Jin Tan, Hana, Arbab, Candy, Choo, Doris Mae Dimatatac, Yee, Low, Hui Wen Chua, Tousif, Kabir, Sabrina, Ngaserin, Lester, Ong, Kiat Tee Benita Tan, Alvin, Tan, Wei-Wen, Ang, Yew-Lam, Chong, Jeffrey, J Leow, Biquan, Liu, Ming Ngan Aloysius Tan, Ern Yu Tan, Kar Yong Wong, Sharon, Yeo, Ladislav, Czako, Branislav, Gális, Kristián, Šimko, Radoslav, Morochovič, Martin, Paulo, Marián, Sedlák, Jan, Grosek, Ales, Tomazic, Leyla Al Mahdawi, Nuhi, Arslani, Andrej, Avsenak, Andrej, Bergauer, Krešimir, Blažević, Dejan, Bratus, Dalibor, Cankoski, Andrej, Cokan, Bojana, Crnobrnja, Andraz, Dovnik, Vojko, Flis, Samo, Fokter, Urska, Gajsek, Minja, Gregorič, Marko, Hazabent, Tomaz, Jagric, Niko, Kavčič, Jure, Knez, Nina, Kobilica, Rok, Kovačič, Lara, Lukman, Urska, Marolt, Jan, Mlakar, Tamara, Mohorko, Andrej, Moličnik, Ivan, Perić, Stojan, Potrč, Milena Senica Verbic, Mateja, Sirše, Jerneja, Vidmar, Adnan Sayid Abdo, Abdifatah Dahir Ali, Abdilaahi Ahmed Hayir, Sadiq, Ibrahim, Afnan, Nuh, Kadra, Omar, Ridwan, Saeed, Nikita, Blake, Cassandra, Ferreira, Corne, Nel, Colin, Noel, Marcel de Kock, Nathan, Kaplan, Emile, Kayombo, Paballo Clinton Khaeane, Asha, Malan, Wikus Wessel Mulder, Daylen, Rutledge, Cornel, Steyn, Gert, Steyn, Naser, Almgla, Mohamed, Daoub, Hammaad, Gamieldien, Thomas, Hilton, Nazmie, Kariem, Maahir, Kariem, Christo, Kloppers, Maritz, Laubscher, Wanga, Mtimkulu, Walid, Mugla, Daniel, Nel, Ferhana, Gool, Timothy, Hardcastle, Wasim, Mahomed, Nivashen, Pillay, Kayla, Rossini, Stephanie Van Straten, Annamart, Laubscher, Adelaide, Lee, Mohammed Yusuf Parker, Sinead, Quirke, Therese Du Preez, Adeline, Jacobs, Reinier, Swart, Modise Zacharia Koto, Neha, Kumar, Imraan, Sardiwalla, Mapuor, Areu, Juan Campos Garcia, Paula, Ferrara, Christoph José Klein Zampaña, Raquel, Lopez, Hernan, Sandoval, Guillermo, Carreño, German Mínguez Ruiz, Conrado Andrés Ros, Raquel Angulo Artal, Luis, Barbier, Guillermo, García-Operé, Marta, Jiménez-Jiménez, Héctor, Marín, Mikel, Oñate, Luis Antonio Pascua-Gómez, María Alexandra Pesántez Peralta, Ibabe Villalabeitia Ateca, Ladislao Cayetano Paniagua, Joan, Camí, Pablo, Collera, Martínez, David, Carlos Javier Gómez Díaz, Jordi Querolt Coll, M Dolors Rosines Cubells, Cristina Soto Montesinos, Guillermo, Triana, Marina, Xicola, Alfonso, Alias, Albert, Baduell, Mariano, Balaguer-Castro, María Pilar Camacho Carrasco, Marina Cámara Vallejo, Borja Campuzano Bitterling, Guillem, Claret, Francisco, J Cuesta-González, Alberto Di Somma, Joaquim Enseñat Nora, Neus, Fabregas, Ada Ferrer Fuertes, Abel, Ferrés, Cesar, Ginesta, Jose Juan Gonzalez Sanchez, Isabel, Gracia, Jhon Alexander Hoyos Castro, Montsant, Jornet-Gibert, Xavier, Morales, Alejandra, Mosteiro-Cadaval, Leire, Pedrosa, José Poblete Carrizo, Marina, Renau-Cerrillo, Luis Alberto Reyes Figueroa, Pedro Roldan Ramos, Jordi Rumià Arboix, Marta, Sabater-Martos, Josep, M Segur, Thomaz, E Topczewski, Jorge, Torales, Ramon, Torné, Pere, Torner, Ricard, Valero, Marian, Vives-Barquiel, Eulalia, Ballester, Alberto Basterra Rincon, Vitiello, Giulia, Belén Martin Arnau, Marta, Gil, Silvia, Martin, Monica, Serrano-Navidad, Mauricio Agüero Mariño, Núria Casanova Torrequebrada, Berta Fabregó Capdevila, Adrián López Campillo, Gemma, Mancebo, Ester, Miralpeix, Blanca, Montcusí, Marina, Munarriz, Ariadna, Salvadó, Josep, M Sole-Sedeno, Clara Téllez Marquès, Ana Centeno Álvarez, Ruth Lopez Gonzalez, Luisana Riba Combatti, Andrea Sanz Llorente, Miguel Bejarano Serrano, Blanca Capdevila Vilaró, Maria Coronas Soucheiron, Mario Cuesta Argos, Irene de Haro Jorge, Yaiza Galvañ Félix, Luis, García-Aparicio, Rebeca, Leal, Albert Malet Contreras, Irene, Martínez-Padilla, Clara, Massaguer, Ines Moraleda Gudayol, María Elena Muñoz Fernández, Paco, Parri, Cristina Pérez Costoya, Javier, Rojas-Ticona, Leopoldo Tapia Moral, Francisco, Vicario, Francesc Angles Crespo, David Bosch Garcia, Berta, Escudero, Carlos Garcia Cardona, Sergi, Bellmunt-Montoya, Javier de la Torre, Úrsula, Acosta, Iago Alvarez Saez, Eva Andreu Riobello, Fernando Ascanio Gosling, Jose, Bagan, Irene, Brana, Bartomeu, Caimari, Marta Cicuendez López Ocaña, Anna, Conesa, Alba de Pablo García-Cuenca, Natalija, Dediulia, Francesc, Duran-Valles, Jordi Giralt López de Sagredo, Maria Jose Gomez-Jurado, Ernesto, Guerra-Farfan, Juan Sebastian Guillén, María Guisasola Rabés, Viviana Andrea Hernández Angel, Maria Jurado Ruiz, Yuri, Loaiza, Manuel, Lopez, Susana, Manrique, Maria Dolores Mateo Arzo, Joan, Minguell-Monyart, Enric Miret Alomar, Sonia Monreal Clua, Víctor Morales Ariza, Clara Morales Comas, Judith, Murillo, Jose Maria Nieto Rodriguez, Elena Vilardell Ortiz, Jorge, Pamias, Montserrat Pascual Pascual Arellano, Remei Perera Sarri, Aleix Pons Bartroli, Nil, Prat, Alfredo Pueyo Ferrer, Rosa Pujol Pina, Jordi, Raurich-Leandro, Maria José Reche Padilla, Joaquín Rivero Déniz, Natalia, Rodriguez, Manuel Saez Barba, Vanessa Sanchez Torrents, Berta, Serrano, María Sol Siliato Robles, Christian Siso Raber, Iñigo, Soler, Maria Carmen Suescun López, Jordi Teixidor Serra, Cristina, Tello-Díaz, Marta Utrilla Pérez, Ramon, Vilallonga, Irene Vives Roselló, Vázquez García César, Mireia, Gili-Bueno, Carlos Gomez Roig, Gloria, González, Aamer, Malik, Maria Del Mar Martí-Ejarque, Mario Rafael Medina Hernández, Carolina, Pozo, Laura, Ruiz-Villa, Nuria, Sierra, Antonio, Valle, Susana, Velasquez, Mirentxu, Arrieta, Daniel, Escobar, Arkaitz, Lara, Alicia, Rojo, Idoia, Villamor, Javier Aitor Zabala Lopez-Maturana, Begoña, Estraviz, Laura Fernández Gómez Cruzado, Melania González de Miguel, David, Lecumberri, Victor Luis Gomez Corujo, Silvia, Bleda, Joaquin De Haro, Carlos, Martínez-Pinedo, David, Padilla-Valverde, Rafael Picón Rodríguez, Francisco Javier Redondo Calvo, Daniel, Sanchez-Pelaez, Alfonso Espinosa Ruiz, Eduardo, Rodriguez, Ignacio Alcalá Rueda, Gonzalo Díaz Tapia, Alvaro Sanchez Barrueco, Maria Dieguez López, Isabel López García, Pilar López-Toribio López, Marina, Bosch, Carolina Curtis Martínez, Alba Fernández Candela, Sandra Lario Pérez, Cristina Lillo García, Clara López de Lerma Martínez de Carneros, Francisco López Rodríguez-Arias, Inmaculada, Oller, Saray, Quinto, Luis, Sánchez-Guillén, Antonio Sanchís López, Álvaro, Soler-Silva, Daniel Triguero Cánovas, Victoria Garcia Peces, Estefania, Hernández-García, Guillermo, Plaza, Rafael Abad Alonso, Francisca Aranda Lozano, Marta Calvo Fernández, Eneko Del Pozo Andres, Josune Etxabe Gurrutxaga, Francisco Javier Fernández Pablos, Francisco Javier Ibáñez-Aguirre, Begoña Ochoa Villalabeitia, Natalia, Ortega, Amaia Sanz Larrainzar, Irune Vicente Rodriguez, Javier Jimenez Miramón, Jose, M Jover, Tamara, Llamero, Jose Luis Ramos Rodriguez, Ainhoa Valle Rubio, Maria Teresa Albiol, Codina, Antonio, Clara, Codony, Ramon Farres Coll, Cristina Farrés Pla, Nuria Gomez Romeu, Santiago, Lopez-Ben, Marcel, Pujadas, Berta, Tió, Francesc, Tuca, Elizabeth, Bárcena, Esther Brea Gómez, Antonio Francisco Guisado Calderón, Elisabeth Fernandez Castro, Montserrat Mairal Fraile, Oscar, Pastor, Cristina García Amador, Raquel Latorre Fragua, Marta, Allue, Pablo, Colsa, Teresa Gimenez Maurel, Raúl Latorre Tomey, Luis Francisco Martín Anoro, Luca, Ponchietti, Alejandra Utrilla Fornals, Carlo, Brugiotti, Carlos Jiménez Viñas, Fátima, Sena-Ruiz, Julio, Plata-Bello, Octavio, Arencibia, Daniel Gonzalez Garcia-Cano, Maria, Laseca, Antonio, Navarro-Sánchez, David Ortiz López, Maria, Pelloni, Sara, Berrocal, Elima Pilar Cagigal Ortega, Jorge, Calvera, Iria, Cervera, Patricia Díaz Peña, Silvia Verónica Domínguez Ovejas, Francisco, Donis, Patricia Fernández Bernabé, Gema, Fraga, Raúl Garcés García, Antonio, García, Elena Garcia De Castro, Antonio García Domínguez, Miguel Angel García García, Judit, Gonzalez, Carles Heredia Llinàs, Inés, Hernández, Norberto Herrera Merino, Carmen Lucero León Gámez, Ana Luis Siles, Maria Marqueta De Salas, Paula Martinez Pascual, Almudena Ortiz Simón, Laura, Osuna, Marta Perez Gonzalez, Antonio Ramos Bonilla, Lorena Rodríguez Gómez, Jose Luis Uquillas, Miguel Angel Alonso Prieto, Marta, Ballesteros-Pomar, Sara Busto Suarez, Mario, Castaño, Laura Castillo Pardo, Mario De Arriba Alonso, Fernando Diez Burón, Anna Farrés Rabanal, Diego Fernández-Samos Fernández, David, Garcia, Cristina García Pérez, Miguel García Sanz, Cesar, Gracia, Javier, Gualis, Gonzalo Gutiérrez Carrillo, Mateo, Hevia, Eva Higuera Miguélez, Gregorio, Laguna, Cristina Lombardia Gonzalez de Lera, Pablo López Martínez, Pasquale, Maiorano, Sergio Marcos Contreras, Elio Martín Gutiérrez, Marta, Molina, Irene, Perez, Teresa Renedo Villar, Luis Angel Suarez Gonzalez, Eva Alvarez Torres, Luz Bueno Rey, Zulay Adriana Calderon Barajas, Ana, M Castaño-Leon, Aida, Fernández, Pablo Garcia Pimentel, Luis, Jimenez-Roldan, Meta, Levstek, Rosalia Navarro Casado, Claudia Olea Vielba, Ana Maria Parada Rodriguez, Igor, Paredes, Patricia, Pascual-Cambero, Miguel Saiz Sánchez-Buitrago, Claudia Sarrais Polo, Victor Zarza Fernandez de Alegria, Mireya, Bonet, Alberto Encinas Vicente, Jose Miguel Villacampa Auba, Maria Dolores Burgueño, Patricia Serrano Méndez, Thomas, W Jorgensen, Mercedes, Martin, Mónica, Huecas, Felipe, Velasco, Verónica Alen Villamayor, Santiago Alonso Bartolomé, Miguel Alonso Juarranz, Luis Felipe Ávila-Ramírez, Javier Buendia Pérez, Barbara, Burgos-Blasco, Enrique Camarero Rodríguez, Paula Campelos Fernández, Claudia, Celotti, Marco Ciappara Paniagua, Ignacio, Cristobal, Alejandro Encinas Bascones, Elena, Fernandez-Martin, Inés Gil Prados, Jesus Gimeno Hernandez, Maria Alejandra Giraldo, Manuel Gomez Cervantes, Noemi Guemes Villahoz, Araceli Hernández Ramos, Maria Cruz Iglesias Moreno, Bibiana Lasses Martínez, Francisco Leyva Rodríguez, Leyre López Antoñanzas, Javier Martín Monterrubio, Jose Maria Martinez-de-la-Casa, Lourdes Montero Cruces, Jesús Moreno Sierra, Jose Maria Muguerza, Alexia Victoria Paluso Montero, Natalia Pérez Romero, Adriana, Poch, Jaime Rodríguez de Alarcón, Adriana Ruano Campos, Rebeca Ruiz Roman, Patricia Saez Carlin, Cristina Sánchez Del Pueblo, Lidia Sotillo Valenzuela, Armando, Galvan, Miguel Ángel García Ureña, Enrique, González, Manuel Medina Pedrique, Alvaro Robin Valle de Lersundi, Carlos San Miguel, Juan, Aragón-Chamizo, Monica, Ballon, Jose, M Barrio, Beatriz Castro Catalan, Laura Cebolla Rojas, Renan Carlo Colombari, Miguel Cuende Diez, Paula Dujovne Lindenbaum, Oscar, Gil-de-Sagredo, Silvia Kayser Mata, Pablo Lozano Lominchar, Yeniffer Tatiana Moreno Salazar, Angela, Moreno-Gutierrez, Melanie, Morote, Uxue, Murgoitio, Nikolas Palma Caucig, Lucía Polanco Pujol, Alejandro, Prosperi, María Belén Ramírez Senent, Diego Fernando Ruiz Chiriboga, Mercedes, Sanz, Maria, Tudela, María Adrien Lara, Raquel, Alarza, Isabel Alonso Sebastian, Mariano Artés Caselles, Laura, Calles-Sastre, Marcos Casas Sánchez, Aritz Equisoain Azcona, Lucía, Fuentes, Lucia Gil Cidoncha, Sofía Herrero Gámiz, Eva Iglesias Garcia, Jose Luis Lucena De La Poza, Mª Eugenia Marín Martínez, Pilar Martín Rodrigo, Joaquin Manuel Muñoz Rodríguez, Verónica, Polaino, Alberto Pueyo Rabanal, Xabier Remirez Arriaga, Xiana, Rial, Miguel Sánchez Suárez, Maria Eugenia Torguet Muñoz, Borja Bazán Inostroza, Lara Blanco Terés, Alba Correa Bonito, Angela de la Hoz, Gustavo, Eisenberg, Javier Garcia Septiem, Jose Maria Lopesino, Rocio, Maqueda, Elena, Martin-Perez, Jose Luis Muñoz de Nova, Julia Revuelta Ramírez, Ana Rodríguez Sánchez, Álvaro Valdés de Anca, Laura Colao García, David Díaz Pérez, Enrique Esteban Agustí, Pablo Galindo Jara, Ana Belén Gallardo, Cesar, Garcia, Maria Gutierrez Samaniego, Miguel Angel Hernandez Bartolome, Lorenzo, Rabadan, Barriga Sánchez Raquel, Beatriz, Diéguez, Miguel, Hernández-García, Carolina Alfonso Carrillo, María Belén Alonso Bartolomé, Estibaliz, Alvarez, Mario, Alvarez-Gallego, Paula, Aragón-Ramos, Pablo Cesar Arteaga Asensio, Luis Asensio Gomez, Diego, Carrion, Nuria, Chavarrias, Alvaro de Arriba, Jose Antonio Gazo Martínez Gazo, Alberto Gegúndez Simón, Juan Gómez Rivas, Natalia Gonzalez Alcolea, Carolina, Gonzalez-Gomez, Sara Gortázar de Las Casas, María Alexandra Heras Garceau, Alicia Hernández Gutierrez, Luis, Lassaletta, Fuad Samir Lopez Fernández, Marta, Mancheño, Blanca, Mateos-Serrano, Isabel Pascual Miguelañez, Maria Fernanda Pedrero Escalas, Julio, Peñarrocha, Yolanda, Perez, Maria Isabel Prieto-Nieto, Teresa Rivera Schmitz, Laura, Rodrigáñez, Ines, Rubio-Perez, Isabel Sanchez Cuadrado, José Ignacio Sánchez Méndez, Jorge Fernando Tone, Carlos Toribio Vazquez, Aitor, Urbieta, Diego Córdova García, Francisca Garcia-Moreno Nisa, Laura, Jiménez, Inmaculada, Lasa, Belen, Matías-García, Fernando, Mendoza-Moreno, Marina Pérez González, Ana Sánchez Gollarte, Alejandro Sanchez Pellejero, Cristina Vera Mansilla, Rafael, Barberá, Lourdes, Montes-Jovellar, Sara Fra Fernández, Nicolas Moreno Mata, Barbara, Algar-Yañez, Gutiérrez, Bérénice, Olga De La Varga-Martínez, Paula, Fernandez-Valdes-Bango, Sandra Maria Gadin-Lopez, José María Martínez-Gómiz, Elena, Nieto-Moreno, Ana, Nieto-Moreno, Montserrat Ocampos Hernandez, Maria Laura Pelegrina-Lopez, Alicia Ruiz Escobar, Elena, Sáez-Ruiz, Beatriz, Vazquez-Rivero, Antonio, Lara, Belén Vielva Del Campo, Fernando Alcaide Matas, Simbad, Costas-Ochoa, José María García Pérez, Elizabeth, Marmol, Paula Troncoso Pereira, Maria Del Pilar Concejo Cutoli, Juan Ramón Gómez López, Juan Carlos Martín Del Olmo, Paloma Guillamot Ruano, Javier Páramo Zunzunegui, Antonio Albarracín Marín Blázquez, Alfonso, Aliaga-Sanchez, Marta María Arroyo Domingo, Miriam Artés Artés, Ana Isabel Avellaneda Camarena, Aida, Blaya, Emny Rochell Bobadilla Romero, Pedro Vicente Fernández-Fernández, Lorena Galindo Iñiguez, Víctor Javier García Porcel, Clara Giménez Francés, Antonio Javier Gomez Poveda, Rebeca Gonzalez Celdran, Francisco Miguel González Valverde, Laura Guillamon Vivancos, Elena, Gurrea-Almela, Alejandra Jara Maquilón, Jose David Jimenez Parra, Abd Al Aziz Lanagrán Torres, Raquel Lax Perez, Carmen Maria Lopez Lopez, Francisco, Machado, Alfonso Marco Garrido, Florencio Manuel Marin Martinez, Victoria Martínez Muñoz, Esther, Medina, Olimpia, Molina, José Manuel Muñoz Camarena, Julian, Onate, Pedro Antonio Parra Baños, Emilio Peña Ros, Enrique, Rubio, Marina Sánchez Robles, Carlos Sanchez Rodriguez, María Valero Soriano, María Teresa Yepes García, Felipe, Alconchel, Andrés Balaguer Román, Valentín, Cayuela, Ana, Conesa, Ana Delegido García, Pedro José Gil Vázquez, Paula Gómez Valles, Francisco, Gómez-Bosch, Vicente, J León-Muñoz, Francisco, Martínez, Alvaro, Navarro-Barrios, Tatiana, Nicolás-López, Pablo Ramirez Romero, Emiliano, Cano-Trigueros, María Concepcion Alonso González, Leticia Gómez Viana, Ana Pastor Zapata, Elisa Contreras Saiz, Tamara Díaz Vico, Maria, Fernandez-Hevia, Luis Joaquín García Flórez, Raquel, Rodríguez-Uria, Sandra, Sanz, Lorena, Solar-Garcia, Aida Suárez Sánchez, Jaume, Gelonch, Dietmar, Reinaldo, Miriam Abdulkarim Polo, Asier, Aguirre, Marta Alomar Bofill, Santiago, Baena, Ashish, Bartakke, Carmen Cabeza Oliver, Marta Castro Suárez, José Andrés Cifuentes Rodenas, Olga Claramonte Bellmunt, Ant Onia Crespí Mir, Anabel De La Llave Serralvo, Mar, Escales, Isabel Rosa Fernández Burgos, Pablo Gandia Gonzalez, Juan Lliteras Jorge, María Cristina Martínez Canto, Javier, Mata, Andreu, Morell, Naila, Pagès, Sara Pérez Palao, Cristian Plaza Valiente, Catalina Ramon Barcelo, Carmen Reyero Fernández, Albert Reyes Claret, Leticia Rodriguez Vaquero, Maialen Saez de Vicuña Salinas, Pilar Santos Cidon, Concepcion, Segura, Aina, Serra, Maria Serra Guivernau, Maria Soler Pedrola, Marta, Tasende, Marta Torrent Lluch, María Inmaculada Valldeperas Hernández, Rosa-Maria, Yañez-Lpez, Andrea, Craus-Miguel, Laura Fernández Vega, Natalia Pujol Cano, Juan José Segura-Sampedro, Laura Colet Oliver, Ivan Dot Pascuet, Mireia, Duart, Isabel Tello Galindo, Eduardo Arrea Salto, Jaume Cámara Cabrera, Marta Camats Terré, Juan Gabriel Castro Ríos, Marta de la Rosa-Estadella, Anna, Fernandez-Colorado, Anna, Gasulla-Rodriguez, Antonio, Gimenez-Gaibar, Elena, Gonzalez, Yeray Maldonado Sotoca, Matilde, Molina-Corbacho, Montserrat Monfort Mira, Josep, Rodoreda, Marta Santos Espí, Arnau Verdaguer Figuerola, Elisa Angela Diego-Alonso, Jaime, López-Sánchez, Luis, Muñoz-Bellvis, Jacobo, Trebol, Borja, Aguinagalde, Cristina Gabriela Alzate Arsuaga, Ainhoa Andres Imaz, Iñigo, Arana, Coro Aranzabal Urrutia, Mikel, Armendariz, Lorena, Arrabal, Iñigo, Augusto, Adolfo, Beguiristain, Laura, Busto, Ainhoa, Cuevas, Itziar De Ariño, Alejandro, Elúa, Leticia, Fernandez, Arantza, Fernandez-Monge, Lander, Gallego, Alba, Garcia, Amaia Garcia Dominguez, Gregorio, Garmendia, Carmen, Grañén, Pelayo Hevia Rodríguez, Maria, Iraola, José Miguel Izquierdo, Aintzane, Lizarazu, Jon Ander Lizarbe, Claudia Cristina Lopes Moreira, Iker, López, Ruth Marquina González, Tania, Pastor, Adrián Recio Ayesa, Ana Paula Riverola Aso, Carballo, Rodríguez, Araceli, Rodrìguez, Maria Inmaculada Ruiz Montesinos, Patricia, Torres, Jose, Undabeitia, Ainara, Villafruela, Maria Barrionuevo Ramos, David, Blanco, Marta, Calderón, Eva Corral Rubio, Angel, Cuadrado-García, Daniela, Cubek, Ignacio, Fariña, Maria Fernandez LLorente, Natalia Flores Amador, Mariana García Virosta, Luis Garcia-Sancho Tellez, Adelina Gonzalez Martinez, María, Hernandez, Rubén Herreros Ruiz-Valdepeñas, Carmen Jimenez Sanchez, Eduardo Llamazares Cobo, María, López, Javier, López-Martin, Teresa Martínez Marivela, Luis Miguel Martinez Parra, Paloma Maté Mate, Paloma, Medrano, Manuel Moriche Carretero, Sara Núñez O'Sullivan, Manuel Ortega Oria de Rueda, María Begoña Pastor Nieto, Clara, Pérez, Antonio, L Picardo, Remedios Revilla Amores, Carmen Rodríguez Haro, Jose Alberto Rojo López, Fatima Sanchez Cabezudo Noguera, Cristina, Sanz, Daniel Serralta de Colsa, Cristina Valor Garcia, Marta Velasco Martinez, Iván Andújar Lara, Aranzazu, Calero-Lillo, Enrique, López-Ruiz, Alberto Díaz García, Alejandro Menéndez Moreno, Luis Eduardo Pérez-Sánchez, Ángela, Pascual, Miguel Adeba García, Marta Alonso Fernández, Javier Alvarez Gama, Roberto, Ballestero, Loreto Berjon De La Vega, Paola Calleja Hermosa, Mariana, Carrillo-Rivas, Alfonso, Casado, Andrea, Cerveró, Bonifacio Cimadevilla Calvo, Patricia Corriols Noval, Paloma de la Dehesa Cueto-Felgueroso, Miren Jasone Diez Zapirain, José Estevez Tesouro, José Antonio Fernández-Dívar Sánchez, Lucia Garcia Alcalde, Juan García Cardo, Tito García Moreno, Daniel, García-López, Belen Garcia-Montesinos Perea, Miren Gonzalez Benito, Rocio, Gonzalez-Aguado, Miguel Ángel Gordo Vega Gordo-Vega, Jose, Gutierrez-Banos, Jaime Jimeno Fraile, Yolanda Jubete Castañeda, Patricia Lopez Gomez, Antonia Jesús López López, David Mato Mañas, Carmelo, Morales-Angulo, Dieter, Morales-Garcia, Sara, Naranjo, Jose Luis Rabago, Jose Manuel Rabanal, Rocio Revuelta Zorrilla, Adriana Reyes Echeverría, Juan Carlos Rodríguez-Sanjuán, Juan Ramón Sanz, Isabel Simal Badiola, Guillermo, Tejón, Enrique Toledo Martínez, Raquel Varea Malo, Begoña, Fadrique, Tania, Funes, Elena González Revilla, Isaias, Alarcón, Daniel Aparicio Sánchez, Pablo Beltran Miranda, Carmen, Cepeda-Franco, María Josefa Cuevas López, Sandra, Dios-Barbeito, Virginia María Durán Muñoz-Cruzado, Carlos Gonzalez De Pedro, Rosa, M Jimenez-Rodriguez, Francisco, Manresa-Manresa, Gabriel, Marin, Cristobalina, Martin-Garcia, Sara, Martínez-Núñez, Juan Manuel Martos Martinez, Lucas, Mengíbar, Felipe Pareja Ciuro, Eduardo Perea Del Pozo, Veronica Pino Diaz, José, Pintor-Tortolero, Claudia, Quintero-Pérez, Maria Luisa Reyes Diaz, Mercedes Rubio Manzanares Dorado, Alejandro Sanchez Arteaga, Ana, Senent-Boza, Luis, Tallon-Aguilar, Jose, Tinoco-Gonzalez, Luis-Cristobal, Capitan-Morales, Juan Cintas Catena, Javier, Valdes-Hernandez, María Del Campo Lavilla, Alina López De Fernández, Miriam Abellan Lucas, Alba Diaz Padillo, Maria Gómez Romero, Linda Grace Puerto Tamayo, El Mostafa El Yaqine Er Raoudi, Melody García Domínguez, María Ángeles Gascón Domínguez, Marta González Pérez, Alba Hernáez Arzoz, Joana San Anton, Cristian, Ruminot, Hander Guillermo Acosta Diaz, Daniella, Laguado, Kristina, Aghababyan, Alba, Jr, Enrique, Artigues, Rocío, Belda, Miguel, Beltran, Jose Ignacio Blanes, Elena Campos Carot, Miriam, Cantos, Laura, Costa, Carolina Ferrer Gomez, José María Gallego Sánchez, Oscar, Gil-Albarova, Juan, Gilabert-Estellés, Emilio Lopez Alcina, Isabel López Sánchez, Severiano Marin Bertolin, Carolina, Martinez-Perez, Antonio Melero Abellán, Claudia Mulas Fernández, Beatriz, Novoa, Ruth, Nuñez, Pablo Renovell Ferrer, Guijarro-Jorge, Ricardo, Carolina Soledad Romero Garcia, Miguel Sanfeliu Giner, Silvia, M West, Enrique, Zapater, Ignacio, Miranda, Ana, Monís, Alejandro Roselló Añón, María José Sangüesa, Jorge Sanz Romera, Marcos, Adrianzén, Maria Barrios Carvajal, Mireia, Bauzá, Ana Benítez Riesco, Jose Antonio Carbonell Lopez, María-Carmen, Fernández-Moreno, Ricardo Gadea Mateo, Francisco, Garcia, Maris Luisa García-Pérez, Luisa Paola Garzon, Ana, Izquierdo, Maria Lapeña Rodríguez, Carlos, León-Espinoza, Fernando, Lopez, Rosa Martí Fernández, Sara Martínez Castro, Berta Monleón López, Isabel Mora Oliver, David, Moro-Valdezate, Ernesto Muñoz Sornosa, Sara Palomares Casasús, Leticia Pérez Santiago, Mara Albert Fort, Reyes, Balanzá, Lorena Bermell Marco, Carla Carratalá Pérez, Claudia Pilar Clemente Tomas, Marta, Córcoles, Jose Ángel Diez Ares, Carlos Domingo Del Pozo, Nuria Estellés Vidagany, Gonzalo, Garrigos, Mar Gimeno Gimeno Vicente, Blanca Alastrue Giner, Segundo, Gomez-Abril, Paloma, Gonzalez, Paula Gonzálvez Guardiola, Guillermo Sebastian Martínez Fernández, Charo Martínez García, Lucía, Martínez-Costa, Luz María Moratalla Charcos, Sergio Navarro Martínez, Carmen, Payá-Llorente, Álvaro Pérez Rubio, Nuria, Peris, Eduardo Picazo Pineda, Jordi Planelles Gómez, Francisco Ripoll Vidal, Andrea, Roca, Enrique, Salmerón-González, Raquel Segura Roselló, Ramon Trullenque Juan, Cristina Verdejo Gimeno, Jose Miguel Zaragozá García, Gema Zomeño Bravo, Marcos Bruna Esteban, Hanna, Cholewa, Milton de Jesus, Matteo, Frasson, Luis Oliver García, Héctor, J Aguado, Antonio Jose Alonso Villalba, Francisco, Ardura, Carmen Elena Badillo Bercebal, María Bedate Núnez, Alvarez-Ramos Begoña Aranzazu, Juan Beltrán de Heredia, Hugo, Bermejo, Juan Berrocal Cuadrado, Maria Bragado González, Juan, Bustamante-Munguira, Raul Calvo Gonzalez, Yolanda, Carrascal, Ana Belén Casas Marcos, María Carmen Cervera, Sergio Chávez Valladares, Ángel Cilleruelo Ramos, Susana, Cortes, Jesús, Crespo-Sanjuán, María, Cuaresma, Luis Antonio Cuellar Martin, Carlos Ferreras García, Alvaro, Fuentes-Martín, Abel, Ganso, Elena García García, Luis, Garcia-Florez, Virginia, Garcia-Virto, Juan, Gatón, Julio Alberto Gobernado Tejedor, Tania Gómez Sanz, Jose Ignacio González Martín, María Begoña Gregorio Crespo, Ana Herranz Arriero, Jose, Herreros, Marta Ibáñez Nieto, César, Infante, Carlos, Jezieniecki, Moises, Juarez, Gregorio de Jesus Labrador Hernandez, Ana Patricia Legido Morán, Ricardo León Fernández, Alejandro, Leon-Andrino, Almudena, Llorente, Maria Lopez Pais, Mauricio Loucel Bellino, Sergio, Martin, Miguel Angel Martin-Ferrero, Gonzalo Martinez Municio, Elvira Mateos Alvarez, José María Matilla, Luis María Merino Peñacoba, Mario, Montes-Manrique, Fernando Natal Álvarez, David, C Noriega, Henar Nuñez Del Barrio, Francisco Javier Ortiz de Solórzano Aurusa, Lucía, Pañeda, Victoria Pascual Escudero, Miguel Pascual Samaniego, Adela, Pereda, Marta Pérez Febles, Laura, Pesquera, Maria, Plata, Emma Puertas Ruiz, Mario, Rodriguez-Lopez, Alejandro Romero de Diego, Ana, Ruano, María Ruiz Soriano, Cristina Sánchez Torralvo, Silvia Santiago Maniega, Bárbara, Segura-Méndez, Clarisa Simon Perez, José, Soro-García, Paula Suárez Mansilla Suárez-Mansilla, Jeancarlos Trujillo Díaz, Mª Esther Valsero Herguedas, Andrea Vazquez Fernandez, Eduardo Velasco García, Ana, Zabalza, Álvaro Zamora Horcajada, Fernando Acebes García, Enrique Asensio Díaz, Martín, Bailón, Alejandro David Bueno Cañones, Alvaro Centeno Velasco, Ekta Choolani Bhojwani, Fernando Labarga Rodríguez, Sara, Mambrilla, Pablo, Marcos-Santos, Toledano, Miguel, David Pacheco Sánchez, Baltasar, Pérez-Saborido, Pilar, Pinto, Katherine, Plua, Javier Sanchez Gonzalez, Vicente, Simo, Rosalía Velasco López, Sandra Veleda Belanche, Fabiola Eugenia Michel Campos, Iciar Muñoz Lindez, Maria, Balluerca, Maite, Camuera, Pablo, Helguera, Imanol, Herrero, Patricia Paunero Vazquez, María, Sánchez-Rubio, Isami, Soeda, María Dolores Arribas Del Amo, Vicente Manuel Borrego Estella, Estefania, Casas, Néstor Castán Villanueva, Daniel Delfau Lafuente, Elena Delgado Blanco, María, Domingo, Ismael Gil Romea, Azucena, Gonzalo, Emilio Lagunas Lostao, Noelia Lete Aguirre, Yaiza Martinez Lahoz, Jesús Víctor Pérez-Tierra Ruiz, Maria Del Mar Soriano, Isabel Valero Lázaro, Esmeralda Carnicer Escusol, Guillermo Pola Bandres, Juan Luis Blas Laina, Beatriz, Cros, Patricio Andrés Freile Pazmiño, David, Garcia-Aguilera, Ana Mejía Casado, Ana, Nogués, Issa Talal El-Abur, Carlos, Yánez, Isabel Gascon Ferrer, Carlos, Gracia-Roche, Ursula María Jariod Ferrer, María Victoria Simón Sanz, Tomas, Uson, Waseem, Ahamed, Sumudu, Jayasinghe, Eranda, Karunadasa, Prathibha, Nelihela, Sujeewa Priyantha Bandara Thalgaspitiya, Dickson, Wickramarathna, Nagenthiram, Harivallavan, Pirashanthan, Nagarasa, Eranga, Perera, Kanapathipillai, Piratheep, Vithranage Srimantha Dewsiri Rodrigo, Meera, Thayalan, Rajendram, Thayaparren, Arulprashanth, Arulanantham, Kanishka De Silva, Gagana, Ganga, Anuja Nadeeshan Kumarasinghe, Mahanada, Udukala, Koculen, Vimaleswaran, Prashanthan, Yogarajah, Ravindri, Jayasinghe, Probhodana, Ranaweera, Mohamed, Rishard, Dharmabandhu, N Samarasekera, Sanjeewa, Seneviratne, Sivasuriya, Sivaganesh, Chamal, Fernando, Nishantha, Mendis, Balasingam, Balagobi, Balasupramaniam, Sathesan, Lanka, Dasanayake, Malitha, Patabendige, Wickramasooriya, Dj, Kugarajh, Ganeshapillai, Sathyamoorthy, Prasanna, Dileepa, Ediriweera, Sumudu, Kumarage, Asanka, Jayawardane, Athula, Kaluarachchi, Pituwala Liyanage Adithya Sirisena, Abubakr, Abubakr, Hozifa, Mohamed, Ismail, Mustafa, Mogahid, Sharfeldein, Samir, Ismail, Reem, Musa, Monira, Sarih, Mussab, Abaker, Eman Adam Abdalla, Mohamad, Abdelbagi, Alsafe, Adlan, Ahmed, Alnaeem, Safa, Atyah, Yasir, Awad, Rsheeda, Dawelbait, Mohamed El Hag, Ibrahim, Elbashir, Sami, Eldirdiri, Samwal, Eldirdiri, Mohammed Eltahier Abdalla Omer, Lana Abdalgadir Ahmed Mohamed, Hiba Hassan Rehmtallah Ahmed, Mohammed Balla Yousif Balla, Abdulmoiz, Aljafari, Abdulmalek, Aljafari, Elsagad, Mohamed, Abdulkader, Mohammad, Abdulkader, Shaar, Mohamed Nafea Shaar, Maab Hussein Yousif Elhafiz, Mohammed Husien Yosif Elhafiz, Abubakr Ali Mohammed Alhassan Humidan, Almigdad, Ali, Hisham, Eljack, Mohamedyasin, Elrashid, Manhal, Ahmed, Albrra, Alhag, Douaa, Ali, Mohammed Ahmed Babikir, Imad, Bakheit, Hytham K, S Hamid, Sami, Mohamed, Walid, Shaban, Nidhal, Siddig, Mohamed, Suliman, Rihab Yasir Abdelmagid, Abubaker, Yassin, Omer, Abbas, Eltahir, Abdelrahim, Muhammed, Ahmed, Mohamed, Elobaid, Adil, Hashim, Ali, Mohamed, Omer, Mohamed, Khalid, Osman, Abdallah, Yousif, Safaa, Abdulaal, Marwa, Elsadig, Mohammed, Hussain, Malaz Amir Ataalmanan, Doha Amir AtaAlmanan, Tebyan Amir AtaAlmanan, Alaa, Elgaili, Maria, Mohamed, Usra, Omara, Alkhansa, Osman, Amna, Osman, Safaa, Saad, Abdelkareem, Ahmed, Ali Adil Ali Karar, Aya, Alhassan, Mohanad, Alsidig, Mohamed, Eljack, Mohammed Ibrahim Mohammed Ali, Awad Kamal Awad Osman, Liena, Mohamed, Samah Ibrahim Omer Mohamed Osman Mohamed Osman, Altayeb, Mohammed, Ayman, Mohammed, Khadija, Muhmmed, Eltahir, Musa, Egbal Sahal Abdelmajed, Khalid Z M, Y Hamid, Omnia M, M Yousif, Mahmoud, Saleh, Osman, Bashir, Yassein, Elhussein, Omar, Madani, Eva, Angenete, Jennifer, Park, Lars, Gillberg, Monir, Jawad, Linas, Pieteris, Yousif, Saeed, Sergej, Safonov, Martin, Spångfors, Henrik, Andersson, Hans, Bahlmann, Karin Björnström Karlsson, Michelle, Chew, Lara, Daham, Lina De Geer, Helen, Didriksson, Gunilla, Gagnö, Carina, Jonsson, Anna, Oscarsson, Pamela, Buchwald, Mathilde, Delorme, Marie-Louise, Lydrup, Shahin, Mohseni, Arvid, Pourlotfi, Souheil, Reda, Kajsa, Anderin, Nina, Blomme, Josefin, Segelman, Malin, Simlund, Anders, Thorell, Fredrik, Wogensen, Daniel, Danielsson, Peter, Elbe, Rebecka, Hultgren, Boel, Hynning, Fredrik, Klevebro, Karin, Lind, Ebba, K Lindqvist, Carl, Montan, Ernesto, Sparrelid, Clara Svenberg Lind, Jeremy, Wales, Andreas, Älgå, Martin, Nordberg, Emil, Pieniowski, Ioannis, Gkekas, Niklas, Löfgren, Karolina, Niska, Robert, Zürner, Silvio, Däster, Otto, Kollmar, Savas, Soysal, Stephanie, Taha-Mehlitz, Athanasios, Tampakis, Dominik Valentin Flury, Marie, Heyne-Pietschmann, Gregor Jan Kocher, Ana, M Calinescu, Barbara, Wildhaber, Markus, Gass, Jürg, Metzger, Andreas, Scheiwiller, Lukas, Briner, Oliver, Dwidar, Steven, Grandjean, Pietro, Ricciardi, Alexandra, Calmels, Christodoulou, Michel, Morena, Antonilli, Dimitrios, Christoforidis, Alessandra, Cristaudi, Jacopo, Galafassi, Maria Luisa Gasparri, Francesco, Mongelli, Martino, Munini, Andrea, Papadia, Sotirios Georgios Popeskou, Alex, Alfieri, Thomas, Bächler, Matteo, Giardini, Christian, Gingert, Laura, Guglielmetti, Inna, Meyer, Tobias, Müller, Daniel, Schöni, Folco, Solimene, Frank, Weidner, Marco, Bueter, Daniel, Gero, Amelie, Müller, Carmen, Portenkirchner, Andreas, Thalheimer, Jeannette, Widmer, Ahmad, Hmaideh, Alaa, Kour, Saleem, Swaes, Omar, Alannaz, Ramez, Aljasem, Ezeddin, Dabbagh, M Wafa Hamoud Alhussein, Amr, Hamza, Mazen, Mohammad, Abd El-Fattah Mouhandes, Mohamad, Shareeda, Mohammad Nour Shashaa, Mousa, Sifat, Sheraa, Tahhan, Rahaf, Toutounji, Mohamed, Abdulrahman, Albaraa, Abdulsalam, Ziad Al Jarad, Hala, Alayyoubi, Dina, Alfarra, Ahmad, Alhamid, Mahmoud, Alnasser, Mulham, Gharib, Ruwaid, Gharib, Obaida, Kabel, Osama, Kherallah, Abdulqader, Klaho, Mohamed Shukri Najjar, Ahmad, Razouk, Joud, Shiekhoni, Wael, Alkhaleel, Amira, Almosa, Mohammad, Aloulou, Maen, Alzaeem, Khaled, Arnaout, Muhamad Zakaria Brimo Alsaman, Mohamad, Estanbouli, Hanadi, Hawa, Ahmad Nbrass Kabawi, Ghina, Maarawi, Yehia, Mashhadany, Sana Shaikh Torab, Waleed, Abd, Tayma Abd Alghafour, Hani, Abdalnour, Nazeeh Al Aktaa, Marwan Al Aliwy, M Maher Al Arje, Tasneem Al Najjar, Ahmad, Al-Mouakeh, Ahmad, Aldakhil, Aos, Alhamid, Hasan, Alhasan, Mohamad Shadi Alkarrash, Jumaa, Alkhamis, Sara, Alshekh, Ahmad Yamen Arnaout, Oula, Azizeh, Mohammed, Dalaleh, Aghyad, Danial, Zain, Douba, Raghad, Ghadri, Mohammad Maen Ghannam, Anas, Ghawi, Luma Haj Kassem, M Yasser Halwani, Shahed, Hamadieh, Mohammad, Hanino, Ala Aldeen Hasan, Haya, Jawish, Nasr Ullah Kabbani, Saadullah, Kabbany, Mohamad, Kadi, Lama, Kadoura, Ahmad Amir Kayali, Ammar, Kayyali, Aya, Kelzia, Amana, Kezze, Abdullah, Khalaf, Maymona, Khayata, Mohammad Nour Kitaz, Mohammad, Kour, Raghad, Makki, Ruqaya, Masri, Joseph, Masri, Noor, Masri, Muhammad, Mazketly, Shiar, Mustafa, Ezzeldin, Nashed, Yaman Qoudra Danial, Hasan, Raslan, Rima, Salem, Mohammed Asaad Salem, Thabet Sayed Bakir, Manaf, Sharabaji, Majd Sheikh Alganameh, Duaa Sheikh Kadro, Joudy, Shurbatji, Mohammad Noor Sultan, Dana, Sultan, Hala, Swied, Bakri Tarras Jarkas, Tayf, Toutounji, Fadi, Ward, Rama, Zazo, Aya, Zazo, Zainab, Zeino, Mohamed, Alaktaa, Wael, Alsado, Hala, Fares, Nouran, Hawa, Hamza, Ibrahim, Abdulmonem, Kawas, Mourad, Niazi, Bayan, Toutounji, Mohammad, Abdow, Mohamad, Ahmad, Tareq, Ahmad, Rawan Al Azhar, Hiba Al Hage Diab, Rahaf Al Mulke, Mohammad, Al-Jadaan, Ahmad, Alhussein, Zahra, Alnajem, Omar, Alneser, Bayan, Alsaid, Elias, Azar, Lubna, Bakr, Ammar, Hamza, Yara, Houdifa, Sami, Jomaa, Samer, Kefo, Hiba, Mardini, Alaa, Mohammad, Fadi, Rayya, Fatima, Razzouk, Mohannad, Saleh, Anwar, Shamandi, Ammar Youzkatli Alkhatib, Omar Abdul Salam, Dany, Ajami, Mohammad, Alhamid, Ahmad, Alkhaledi, Danny, Hadidi, Massa, Jabra, Mamdouh, Kallas, Antoine, Laktine, Joelle, Naem, Naya, Naoum, Ghena Mohammed Fawaz Ashour, Ahmad, Alhouri, Deema, Fallouh, Ahmad, N Mohammad, Ahmad, Rmman, Ali, Slitin, Christine, Tanos, Ibrahim, Wakim, Hanaa, Zahrawi, Majd, Abouassi, Layth, Abouassi, Ayham, Aboutrab, Basel, Ahmad, Ahmad Mustafa Ahmad, Aya, Ahmad, Afaf, Ahmad, Mohamad, Alabras, Mohammad, Albasheer, Ola, Alkasser, Mhd Khaled Alkasser, Ali, Alkhdor, Marah, Azkoul, Mohammad Karam Chaaban, Haya, Deeb, Basel, Jazieh, Basel, Kouz, Youssef, Kozah, Raied, Mohamad, Ammar, Mohammad, Mhd Zied Nasri, Mohammed Mouaz Shebani, Mohammed, Shwin, Alaa, Sommaq, Amal, Youssef, Tala Al Asadi, Suhad, Alkhateb, Rasha Khalil Alsayyad, Roula, Altom, Mhd Amin Alzabibi, Batoul, Bakkar, Hlma, Ismail, Salma Khadem Alsrouji, Sara, Melhem, Mohamad, Sankari, Mosa, Shibani, Noura, Shujaa, Ibrahim, Adham, Salma, Al-Houssami, Maram, Balouli, Yazan, Rahmeh, Simon, Yanni, Sally, Yousef, Aline, Ahmad, Marah, Ali, Abdulrahman, Almjersah, Aya, Almoustafa, Hiba, Dahhan, Bashar Haj Hassan, Alaa, Hamdan, Salah, Hammed, Rawan, Harfoush, Rama, Hasan, Natalie, Jarkas, Moufid, Mahfoud, Ahmed, Moussa, Alaa, Sulaiman, Siba, Suliman, Yu-Ning, Hu, Jun-Neng, Roan, Meng-Ta, Tsai, Yi-Chen, Wang, Thammawat, Parakonthun, Nicha, Srisuworanan, Voraboot, Taweerutchana, Somcharoen, Saeteng, Sophon, Siwachat, Apichat, Tantraworasin, Danielle, Dimsoy, Shane, Khan, Akash, Ramsaroop, Shivanand, Ramsubhagh, Karim, Ayed, Oussama, Baraket, Mohamed Hedi Ghalloussi, Abbassi, Imed, Nahla, Kechiche, Waad, Farhat, Ammar, Houssem, Erdal Birol Bostanci, Volkan, Oter, Erol, Pişkin, Cihangir, Akyol, Sibel, Demirel, Mehmet Ali Koç, Can, Konca, Özge, Yanık, Basak, Bolukbasi, Huseyin, Gobut, Emre, Gülçek, Kerim, Karabulut, Ramazan, Kozan, Farshad, Noori, Elif, Özeller, Can, Şahin, Ali, Yalcinkaya, Mesut, Yavaş, Aydın, Yavuz, Utku, Akgor, Omer, Cennet, Hilmi Anil Dincer, Murat, Gultekin, Nazlı, Orhan, Mustafa, Oruç, Serdar, Culcu, Lütfi, Doğan, Cemil, Yüksel, Alp, Yildiz, Aybala, Yildiz, Perihan, Ekmekçi, Baturay Kansu Kazbek, Ülkü Ceren Köksoy, Deniz Serim Korkmaz, Zeynep Şahan Çetinkaya, Elif Aybeniz Yildirim, Hakan, Yilmaz, Metin, Yığman, Nasuh Utku Dogan, Selen, Doğan, Mehmet, Sakinci, Ozgen, Isik, Murat, Şen, Tuncay, Yılmazlar, Utku, Özgen, Ugur, Sungurtekin, Yener, Aydin, Ilker, Ince, Ali Bilal Ulas, Hüseyin Cahit Yalçın, Mehmet, Kaplan, Tuğba, Kaplan, Elif Tugce Kaplan, Afag, Aghayeva, Bilgi, Baca, Inci, Sahin, Zumrud, Aliyeva, Akif Enes Arikan, Erman, Aytac, Onur, Dülgeroğlu, Volkan, Ozben, Cihan, Uras, Emre, Sivrikoz, Ismail Ahmet Bilgin, Bahadır, Bozkırlı, Güralp Onur Ceyhan, Ismail, Hamzaoglu, Halil, Kara, Tayfun, Karahasanoğlu, Olus, Api, Mehmet, Ceyhan, Aylin Pelin Cil, Telce Aysen Gurbuz, Cumhur, B Lent Urman, Ahmet, Akbas, Yunus Emre Aktimur, Yuksel, Altinel, Fikret, Calikoglu, Serdar, Demirgan, Ahmet Guray Durmaz, Gulcin, Ercan, Candas, Ercetin, Hasim Furkan Gullu, Nadir Adnan Hacım, Serhat, Meriç, Kamil, Özdoğan, Merve, Tokocin, Mehmet Alim Turgut, Talar, Vartanoglu, Hakan, Yigitbas, Hüsnü, Aydın, Ece, Bahçeci, Mestan, Bilmez, Elif, Binboğa, Sinan, Binboga, Gokhan, Demirayak, Bengi, Demirayak, Keziban, Doğan, Ahmet Cem Dural, Murat, Ekin, Sina, Ferahman, Fatih, Guven, Mehmet, Karabulut, Sema, Karakaş, Selçuk, Köse, Ayşe Büşra Önder, Ismail Umut Onur, Nuri Alper Sahbaz, Levent, Yaşar, Ulviye, Yigit, Güneş Özlem Yıldız, Ümmühan Zeynep Bilgili, Bayram, Doğan, Cevper, Ersoz, Abdullah, Ilktac, Senad, Kalkan, Eyyüb Selim Ünlü, Halil, Alis, Süleyman, Büyükaşık, Burak, Kankaya, Oguzkagan, Batikan, Ensar, Çakır, Musa Murat Caliskan, Mahmut Emin Çiçek, Anil, Demir, Selim, Doğan, Emre, Erdoğan, Mert, Güler, Muhammed, Gürlük, Ufuk Oguz Idiz, Rozan, Kaya, Cebrail, Oğuz, Ömer Akay Ömer, Serkan Süleyman Özpak, Hüsnü, Şevik, Mert Mahsuni Sevinc, Cihad, Tatar, Oğuzhan, Tekin, 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Yanar, Ahmet, Akmercan, Gül, Çakmak, Tuncay, Kötan, Tunc, Lacin, Ayten, Saracoglu, M Umit Ugurlu, Tumay, Umuroglu, Tevfik Kıvılcım Uprak, Esra Yamansavci Şirzai, Bedrettin, Yıldızeli, Elif, Baran, Emre, Bozkurt, Sinan, Ömeroğlu, Mert, Tanal, Aydın Eray Tufan, Mehmet, Uludag, Gürkan, Yetkin, Murat, Kalın, Omer Faruk Ozkan, Hanife Şeyda Ülgür, Tayfun, Bisgin, Muhammet Berkay Sakaoglu, Selman, Sökmen, Deniz, Caglar, Candan, Cicek, Demre, Delipinar, Emre, Divarci, Egemen, Ozdemir, Hilmican, Ulman, Seda Dilek Yetut, Feyme, Zafer, Ismail, Sert, Burçin, Abud, Murat, Akalin, Cengiz, Aydin, Bulent, Calik, Emine Burcu Cigsar, Semra Demirli Atıcı, Ayberk, Dursun, Mustafa, Emiroglu, Hüseyin, Erdinç, Tayfun, Kaya, Gizem, Kilinc, Yasemin, Kirmizi, Merve Dilara Öney, Mustafa Onur Oztan, Semra, Salimoğlu, Cem, Tugmen, İbrahim, Uyar, Sertaç Ata Güler, Alican, Güreşin, Ozan Can Tatar, Nihat Zafer Utkan, Kemal, Arslan, Mustafa Bilal Hamarat, Ismail, Hasirci, Mehmet Serkan Ozkent, Mehmet Eşref Ulutaş, 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Burks, Allen, Zhou, Djanira, Fernandes, Maha, Haqqani, Nicolette, Jabbour, David, Novikov, Joseph, Sabra, Paul, Tornetta, Lauren, Tracy, Keianna, Vogel, Joanna, Wang, Shawn, Wang, Shaun, Wason, Emily, Berner, Ander Dorken Gallastegi, Mohamad El Moheb, Anthony, Gebran, Marilyn, Heng, Santiago Lozano Calderon, Michael, Mctague, Christopher, Melnic, Andy, Park, Anna, Goldenberg-Sandau, Rebecca, Platoff, Lisa, Shea, Debra, Manning, Romeeka, Perkins, Samuel, Ross, Kyle, Thompson, Grace, Chang, Dustin, Dehart, Jared, Ourieff, Rosalinda, Alvarado, Anuradha, Bhama, Daniel, Deziel, Amir, Dorafshar, Henry, Govekar, Brian, Gulack, Dana, Hayden, George, Kokosis, Andrea, Madrigrano, Keith, Millikan, Jonathan, Myers, Cristina, O'Donoghue, Philip, Omotosho, Sam, Pappas, Srikumar, Pillai, Thea, Price, Scott, Schimpke, Ami, Shah, Deana, Shenaq, Nicole, Siparsky, Alfonso, Torquati, Peter, Tsambarlis, Srinivas, Vourganti, Al-Faraaz, Kassam, Ralph, Quillin, Mauro, Bravo, Elyad, Ekrami, Kai, Li, Alparslan, Turan, Cassie, Decker, Elizabeth, A Hennessy, Thomas, Schroeppel, Zachery, Stillman, Gary, Schwartz, Salah, Aoun, James, Caruso, Clay, Burlew, Julie, Clark, Kendyll, Gartrelle, David, Kwon, Kristin, Colling, Andrew, Barbas, Raquel, Bartz, Sarah, K Dotters-Katz, Tressa, Ellett, Etienne, Flamant, Hesham, Gabr, Dilraj, Grewal, George, Kasotakis, David, Kerr, Vijay, Krishnamoorthy, Alexander, Lazarides, Justin, Ma, Sachin, Mehta, Lucy, Meyer, Courtney, Mitchell, Demetrios, Moris, Diego, Schaps, Zohal, Ghulam-Jelani, Motasem, Refaat, Torre, Soderlund, Amna, Ali, Airi, Katoh, Krista, Kaups, Leigh Ann O'Banion, Yazen, Qumsiyeh, Jessica, Simpkins-Fresno, Murad, Almasri, Gauri, Kulkarni, Hisham, Marwan, Mohammad, Mehdi, Rasaq, Olaosebikan, Camilo, Velasquez, Rodrigo, Arrangoiz, Jeronimo Garcialopez De Llano, Adrian, Legaspi, Maria Fernanda Mijares Olivo, Amit, Sastry, Vanitha, Vasudevan, Hector, Garcia-Chavez, Atif, Iqbal, Yesenia, Rojas-Khalil, Malke, Asaad, Charles, Butler, Cameron, Gaskill, Patrick, Hensley, Jose, Karam, Matthew, Katz, Huan, Nguyen, Alberto, Pieretti, Christina, L Roland, Perel, Baral, D David Beahm, German, Berbel, Andres, Bur, Shea, Carver, Austin, Findley, Christopher, A Guidry, Megan, Hedlund, Corey, Hounschell, Sean, Kumer, Kelsey, E Larson, Derek, Marlor, Madhuri, Reddy, Scott, Turner, Alissa, Urich, Alexander, Cavalea, Brian, Daley, Bailey, Humphreys, Rachel, Savoy, Mary, Leech, Andrew, Loehrer, Kari, Rosenkranz, Avi, Bhavaraju, Nolan, Bruce, Lyle, Burdine, Kyle, Kalkwarf, Mary, Kimbrough, Garrett, Klutts, Joseph, Margolick, Tamara, Osborn, Anna, Privratsky, Matthew, Roberts, Jennifer, Baker, Peyman, Benharash, Ronald, W Busuttil, Robert, B Cameron, Joseph, Dinorcia, Joseph, Hadaya, Farnaz, Haji, Lien, Hua-Feng, Catherine, Juillard, Minna, Lee, Garrett, Salzman, Gregory, Senofsky, Richard, J Shemin, Jeannie, Shen, Carlie, Thompson, Areti, Tillou, Elizabeth, Bruenderman, Samuel, Carson, Clayton, Ellis, Farid, Kehdy, Robert C, G Martin 2nd, Tyler, Mouw, Amy, Wise, Linda, Britton-Zier, Julie, Dunn, Benjamin, Massey, Chathurika Samudani Dhanasekara, Thomas, Wyatt, Daniel, Abbott, Eugene, Foley, Stephanie, Savage, Patrick, Schwartz, Syed Nabeel Zafar, Lauren, Camp, Ruth, A Lewit, Alessia, Cioci, Amber, Collier, Gareth, Gilna, Neha, Goel, Joshua, Kronenfeld, Rebecca, Saberi, Eva, Urrechaga, Juan, Figueroa, Basil, Karam, Rachel, Morris, Christopher, J LaRocca, Archana, Ramaswamy, Steven, Waisbren, Jacob, Ankeny, Rahel, Ghebre, Jane Yuet Ching Hui, Eric, Jensen, Jordan, Mattson, Rachel, Vogel, Emily, Colonna, Frederick, Endorf, Rachel, M Nygaard, Alva, Bethurum, Rohan, Bhalla, David, Bichell, Christopher, Bonfield, Silky, Chotai, Michael, Dewan, Alexander, Hawkins, Aimal, Khan, J Matthew Kynes, Alexandra, Mata, Christopher, Wallis, Camila, Walters, Alice, Wang, Irving, Zamora, Lindsey, Zamora, Marah, Maayah, Melanie, Sion, Sarah, Ullrich, Dalia, Alqunaibit, Kiah, Andrews, Danielle, Friedman, John, Mcnelis, Yasmin, Abedin, Brian, Batko, Anthony, Colon, Sofia, Gabrilovich, Carma, Goldstein, Christina, Gory, Janmejay, Hingu, Brian, Leoce, Anh, Nguyen, Guergana, Panayotova, Ruchi, Ram, Deviney, Rattigan, Jerette, Schultz, Sara, Solar, John, Stein, Grace, Tsui, Elizabeth, Warnack, Apostolos, Gaitanidis, Leon, Naar, Robert, Sinyard, Sophia, Angelides, Laura, Fitzmaurice, Alexander, Himstead, Mehraneh, Jafari, Zeljka, Jutric, Kari, Kansal, Lydia, Kirillova, Isabella, Kuo, Kapila, Patel, Erika Linmey Tay Lasso, Maki, Yamamoto, Maleeha, Ahmad, Steven, Chang, Gary Alan Bass, Benjamin, Braslow, Daniel, Dempsey, Caoimhe, Duffy, Daniel, Holena, Jonathan, Imran, John, Keogh, Cara, Lorenzi, Niels, Martin, Mark, Seamon, Lauren, Huckaby, Katrina, Morgan, Caroline, Rieser, Lauren, Rosenblum, Cindy, Teng, J Michael DiMaio, Mohanad, Hamandi, Mary, Hoffman, Allison, T Lanfear, Michael, Connolly, Benjamin, Hall, Tareq, Kheirbek, Elizabeth, Renaud, Kevin, Behm, Judy, Boughey, Kristin Cardiel Nunez, Sean, Cleary, Mihai, Dumbrava, Travis, Grotz, James, Jakub, Rahul, Kanade, David, Larson, Sherief, Shawki, Dennis, Wigle, Haradeen, Dhillon, Avni, Suri, Leonardo Weber Graeff, Ahmed, Elshabrawy, Grace Ihsiu Todd, Mark, Davies, Yan, Qi, Walter, Biffl, Kathryn, Schaffer, Sarah, Averbach, Terry, Curry, Alexandra, Schwartz, Mary Kathryn Abel, Veronica, Andaya, Kristina, Benirschke, Katherine, Bigay, Marissa, Boeck, Lee-Lynn, Chen, Lee-May, Chen, Huey-Lan, Chern, Amanda, Compadre, Patricia, Conroy, Alexa, Glencer, Patrick, Ha, Barbara Cs Hamilton, Johannes, R Kratz, Rondall, Lane, Rex, H Lee, Brenda, Nunez-Garcia, Richard, O'Donnell, Doruk, Ozgediz, Paul, Park, Ankit, Sarin, Ipsit, Shah, Bonnie, Sheu, Madhulika, Varma, Katherine, Wai, Rosanna, Wustrack, Mary Jue Xu, Melissa, Zimel, Pedro, Escobar, Meredid Maldonado Santiago, Mohammad, Azam, Asad, Choudhry, Eric, Hammond, William, Marx, Jihad, Abbas, Somya, Al-Embideen, Carol, Angel, Bailea, Bobich, Raul, Bosio, Gregory, Georgiadis, Tahir, Jamil, Maria, Kenner, Meghan, Lark, Tamara, Maghathe, Sonia, Masih, Gabriel, Naimy, Kristin, O'Mara-Gardner, Emily, Rady, Roberta, Redfern, Jack, Sample, Joseph, Sferra, Kaitlyn, Sharp, Jessica, Shoemaker, Stephen, Stanek, John, Stengle, Hibba, Sumra, Jeffrey, M Sutton, Faris, Azar, Anne, Fischer, Jaymie, Henry, Lawrence, Lottenberg, Mario, Rueda, Sasha, Thiel, Adel, Bozorgzadeh, John, Kelly, Armando Salim Munoz Abraham, Erin, Scott, Camila, Haro, Andrés, Pouy, Gastón, Acuña, Sofia, Álvarez, Ana Carmen Carbajal, Fabiola, Castedo, Diego, Pereiranuñez, Helena, Sobrero, Josefina, Tarigo, Rafat, Al-Saban, Fatima, Al-Eryani, Siham Al Maqtari, Sahar, Al-Maqtari, Mahmmoud, Abdualqader, Majed, Aeed, Ghadeer Al Sanany, Anwaar Al Dhafif, Buthina Al Jarmozi, Saba, Al-Ameri, Awsan, Al-Dhaheri, Dhyia Alhuq Al-Surimi, Amira, Alakhdury, Sabreen, Alashmali, Zainab, Alattas, Manar, Alduba'Ai, Hamdan, Aldumaini, Wafa, Alhaddad, Abdelrahman, Alharazi, Nawal, Alhemyari, Adnan, Alhumaida, Maniee, Aljabri, Hassan, Almarashi, Zuhoor, Almohanady, Marwa, Alodine, Nooraldin, Alqasemi, Basma, Alqudaimi, Ansam Mohammed Ghaleb Alrobaiee, Mohammed, Alsabri, Radfan, Alsalal, Ramzi, Alsayadi, Musaed, Alsayadi, Reem, Alshaipani, Ebrahim, Alsharabi, Nora, Atiah, Hadeel, Bajjah, Muhib, Esmael, Asma, Ghallab, Rana, Ghannam, Adwa'A, Hamid, Lina, Hashem, Sara, Saif, Shaima, Sayad, Nawras, Shaban, Amatallah Hadi Shamsan, Sarah, Shream, Amal, Shukri, Shahd, Zeid, Nabila, Abdullah, Abdulrahman Faisal Al-Garadi, Ahmed, M Ali Al-Radhi, Norhan, Naji, Shaima'A, Nasser, Areej Taha Al Anaib, Ebrahim, Abdurab, Fadhl Al Muhtadi, Amer, Al-Hebbah, Ahmed, Al-Madhrahi, Shehab, Al-Mahdi, Sakhr Abdulhakeem Al-Maswari, Ayman, Al-Oqabi, Zakarya Abdullah Al-Zaazaai, Karim, Al-Zazay, Ali, Alafif, Asem, Albzzaz, Lina, Alqalisi, Mohammed, Alrezami, Haneen, Alshargabi, Mokhtar, Alshargabi, Hossam, Ghanem, Kareem, Saeed, Rasheed, Shalabi, Fareed, Showqi, Miriam, Maimbo, Catherine, Mkandawire, Mulaya, Mubambe, Theresa, Nkole, Vanessa, Savopoulos, Patricia, Shinondo, Chabwera, Shumba, Penias, Tembo, Shelton, Chivanga, Ngqabutho, Dube, Handsome, Dube, Daniel, Dzinotyiwei, Ronald, Makanda, Moses, Mangena, Partson, Maphosa, Derek, Matsika, Proud, Mawere, Nkosikhona, Moyo, Assel, Moyo, Arnold, Muguwu, Simbarashe, Mungazi, Garikai, Mwale, Gamuchirai, Ndabvonga, Mambote Crispin Olivier Ntoto, Hardlife, Ranganai, Ernesto Sánchez Castillo, Oltah, Tshuma, Grace, Gwini, Vimbai Moyana Muguto, Gilbert, Moyo, Trust, Mushawarima, Tinashe, Shoko, Rorisang, Jamela, Marvellous, Machiri, Eric, Shumba, Antony, Chengahomwe, Yemurai, Bikwa, Maxwell, Chimhina, Jeremy, Marume, Kudzayi, Munanzvi, Precious G, T Mutambanengwe, Federico, Ferrari, Marco, Fontanella, Franco, Odicino, Romano, Vito, Nepogodiev D, Emanuele Cammarata, Sofia Campanella, Daniela Canzonieri, Adriana Cordova, Federico De Michele, Ettore Dinoto, Mara Franza, Leo Licari, Daniele Matta, Domenico Mirabella, Felice Pecoraro, Roberto Pirrello, Pierfrancesco Pugliese, Fernando Rosatti, Giuseppe Salamone, Francesca Toia, Massimiliano Tripoli, Nepogodiev, D, Rosati, R, Surgery, Medicine and Pharmacy academic/administration, Basic (bio-) Medical Sciences, Surgical clinical sciences, Faculty of Medicine and Pharmacy, Gastroenterology, Medical Oncology, Clinical sciences, Breda, João, ARD - Amsterdam Reproduction and Development, Paediatric Surgery, AGEM - Amsterdam Gastroenterology Endocrinology Metabolism, AGEM - Endocrinology, metabolism and nutrition, Graduate School, Tytgat Institute for Liver and Intestinal Research, Laura Alberici, Filippo Antonacci, Alessandro Arena, Angela Belvedere, Fabio Bernagozzi, Paolo Bernante, Pietro Bertoglio, Lorenzo Bianchi, Maria Bisulli, Barbara Bonfanti, Safia Boussedra, Jury Brandolini, Crescenzo Cacciapuoti, Stefano Cardelli, Riccardo Casadei, Matteo Cescon, Alessandro Cipolli, Riccardo Cipriani, Alfredo Conti, Luca Contu, Francesco Costa, Niccolo’ Daddi, Eugenia De Crescenzo, Pierandrea De Iaco, Alessandra De Palma, Massimo Del Gaudio, Anna Nunzia Della Gatta, Giampiero Dolci, Giulia Dondi, Matteo Droghetti, Sergio Nicola Forti Parri, Elena Garelli, Chiara Gelati, Giuliana Germinario, Federico A. Giorgini, Carlo Ingaldi, Elio Jovine, Kenji Kawamukai, Antonio Lanci Lanci, Raffaele Lombardi, Maria Elisa Lozano Miralles, Claudio Marchetti, Michele Masetti, Francesco Minni, Daniele Morezzi, Daniele Parlanti, Alice Pellegrini, Anna Myriam Perrone, Anna paola Pezzuto, Marco Pignatti, Gianluigi Pilu, Valentina Pinto, Gilberto Poggioli, Silvana Bernadetta Puglisi, Diego Raimondo, Matteo Ravaioli, Claudio Ricci, Sara Ricciardi, Francesco Ricotta, Roberta Rizzo, Angela Romano, Matteo Rottoli, Riccardo Schiavina, Renato Seracchioli, Matteo Serenari, Margherita Serra, Piergiorgio Solli, Gioia Sorbi, Mario Taffurelli, Marta Tanzanu, Achille Tarsitano, Marco Tesei, Gabriele Vago, Tommaso Violante, Simone Zanotti, Tommaso Frisoni, leonardo solaini, giorgio ercolani, Fruscio, R, Ornaghi, S, Collaborative, Covidsurg, Collaborative, Globalsurg, Palmisano, Silvia, de Manzini, Nicolo', Žundienė, Laura, Dulskas, Audrius, Kuliavas, Justas, Čekauskas, Albertas, Kielaitė-Gulla, Aistė, Poškus, Tomas, Strupas, Kęstutis, Želvys, Arūnas, COVIDSurg Collaborative, GlobalSurg Collaborative, Department of Surgery, HUS Abdominal Center, Simoes, Jff, Li, E, Picciochi, M, Glasbey, Jc, Baiocchi, G, Blanco-Colino, R, Chaudhry, D, Alameer, E, El-Boghdadly, K, Wuraola, F, Ghosh, D, Gujjuri, Rr, Harrison, Em, Lule, H, Kaafarani, H, Khosravi, M, Kronberger, I, Leventoglu, S, Mann, H, Mclean, Ka, Mengistu, Gm, Modolo, Mm, Ntirenganya, F, Norman, L, Outani, O, Pius, R, Pockney, P, Qureshi, Au, Roslani, Ac, Satoi, S, Shaw, C, Bhangu, A, Omar, Om, Ahmed, Wur, Argus, L, Ball, A, Bywater, Ep, Brar, A, Dawson, Be, Duran, I, Elhadi, M, Jones, C, Kamarajah, Sk, Keatley, Jm, Lawday, S, Marson, Ej, Ots, R, Santos, I, Taylor, Eh, Trout, Im, Varghese, C, Venn, Ml, Xu, W, Dajti, I, Gjata, A, Kacimi, Seo, Boccalatte, L, Cox, D, Townend, P, Aigner, F, Kronberger, Ie, Samadov, E, Alderazi, A, Hossain, K, Padmore, G, van Ramshorst, G, Lawani, I, Cerovac, A, Delibegovic, S, Gomes, Gma, Buarque, Il, Gohar, M, Slavchev, M, Nwegbu, C, Agarwal, A, Martin, J, Ng-Kamstra, J, Olivos, M, Lou, Wh, Ren, Dl, Calvache, Ja, Rivera, Cjp, Hadzibegovic, Ad, Kopjar, T, Mihanovic, J, Jimenez, Pma, Gouvas, N, Klat, J, Novysedlak, R, Amisi, N, Christensen, P, El-Hussuna, A, Batista, S, Lincango-Naranjo, E, Emile, S, Sandoval, Daa, Dhufera, H, Hailu, S, Mengesha, Mg, Kauppila, Jh, Arnaud, Ap, Demetrashvili, Z, Albertsmeier, M, Lederhuber, H, Loffler, Mw, Acquah, Dk, Ofori, B, Tabiri, S, Metallidis, S, Tsoulfas, G, Aguilera-Arevalo, Ml, Recinos, G, Mersich, T, Wettstein, D, Kembuan, G, Milan, Pb, Khosravi, Mh, Mozafari, M, Hilmi, A, Mohan, H, Zmora, O, Gallo, G, Pata, F, Pellino, G, Fujimoto, Y, Kuroda, N, Abou Chaar, Mk, Ayasra, F, Fakhradiyev, I, Hamdun, Ih, Jin-Young, J, Jamal, M, Karout, L, Gulla, A, Rasoaherinomenjanahary, F, Samison, Lh, Sanchez, Iid, Gonzalez, D, Martinez, L, Martinez, Mj, Nayen, A, and Ramos-De la Medina, A
Subjects: Male, Vascular damage Radboud Institute for Health Sciences [Radboudumc 16], MULTICENTER, infectious diseases, 0302 clinical medicine, 030202 anesthesiology, Anesthesiology, Cirugía, 80 and over, Prospective Studies, Young adult, Child, Lung, Aged, 80 and over, COVID-19, delay, SARS-CoV-2, surgery, timing, SARS‐CoV‐2 infection, Operative, Child, Preschool, Pneumonia & Influenza, Infection, Cohort study, Human, medicine.medical_specialty, Clinical Sciences, Sars-cov-2, GlobalSurg Collaborative, Settore MED/28 - MALATTIE ODONTOSTOMATOLOGICHE, 03 medical and health sciences, Clinical Research, Biodefense, Correspondence, Humans, PULMONARY COMPLICATIONS, CRIANÇAS EM IDADE PRÉ-ESCOLAR, Aged, Science & Technology, Cirurgia, Prevention, Infant, Odds ratio, Pneumonia, Prospective Studie, Clinical research, Surgery, Human medicine, 610 Medizin und Gesundheit, 1109 Neurosciences, Internationality, Settore MED/29 - CHIRURGIA MAXILLOFACCIALE, Settore MED/18 - CHIRURGIA GENERALE, Adolescent, Adult, Cohort Studies, Female, Middle Aged, Surgical Procedures, Operative, Time, Young Adult, Practice Guidelines as Topic, gastroenterology, Medicine and Health Sciences, 030212 general & internal medicine, Prospective cohort study, Mortality rate, Covid19, Infectious Diseases, Patient Safety, medicine.symptom, 6.4 Surgery, Life Sciences & Biomedicine, 610 Medicine & health, COVID-19, SARS-CoV-2, delay, surgery, timing, Asymptomatic, NO, COVIDSurg Collaborative, Vaccine Related, All institutes and research themes of the Radboud University Medical Center, medicine, Mortalitat, ddc:610, Mortality, Preschool, LS7_4, Surgical Procedures, business.industry, Neurosciences, Evaluation of treatments and therapeutic interventions, 1103 Clinical Sciences, 3126 Surgery, anesthesiology, intensive care, radiology, Reconstructive and regenerative medicine Radboud Institute for Health Sciences [Radboudumc 10], Anesthesiology and Pain Medicine, Emerging Infectious Diseases, Good Health and Well Being, Mortalidad, Cohort Studie, business
Abstract: Peri-operative SARS-CoV-2 infection increases postoperative mortality. The aim of this study was to determine the optimal duration of planned delay before surgery in patients who have had SARS-CoV-2 infection. This international, multicentre, prospective cohort study included patients undergoing elective or emergency surgery during October 2020. Surgical patients with pre-operative SARS-CoV-2 infection were compared with those without previous SARS-CoV-2 infection. The primary outcome measure was 30-day postoperative mortality. Logistic regression models were used to calculate adjusted 30-day mortality rates stratified by time from diagnosis of SARS-CoV-2 infection to surgery. Among 140,231 patients (116 countries), 3127 patients (2.2%) had a pre-operative SARS-CoV-2 diagnosis. Adjusted 30-day mortality in patients without SARS-CoV-2 infection was 1.5% (95%CI 1.4-1.5). In patients with a pre-operative SARS-CoV-2 diagnosis, mortality was increased in patients having surgery within 0-2 weeks, 3-4 weeks and 5-6 weeks of the diagnosis (odds ratio (95%CI) 4.1 (3.3-4.8), 3.9 (2.6-5.1) and 3.6 (2.0-5.2), respectively). Surgery performed ≥ 7 weeks after SARS-CoV-2 diagnosis was associated with a similar mortality risk to baseline (odds ratio (95%CI) 1.5 (0.9-2.1)). After a ≥ 7 week delay in undertaking surgery following SARS-CoV-2 infection, patients with ongoing symptoms had a higher mortality than patients whose symptoms had resolved or who had been asymptomatic (6.0% (95%CI 3.2-8.7) vs. 2.4% (95%CI 1.4-3.4) vs. 1.3% (95%CI 0.6-2.0), respectively). Where possible, surgery should be delayed for at least 7 weeks following SARS-CoV-2 infection. Patients with ongoing symptoms ≥ 7 weeks from diagnosis may benefit from further delay. ispartof: ANAESTHESIA vol:76 issue:6 pages:748-758 ispartof: location:England status: published
Published: 2021
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32. SARS-CoV-2 infekcijos įtakos 30 dienų pooperaciniam laikotarpiui analizė ir literatūros apžvalga

Author: Koženevskis, Šarūnas, Kaminskas, Ąžuolas Algimantas, Kielaitė-Gulla, Aistė, Strupas, Kęstutis, and Poškus, Tomas
Published: 2021

33. Ankstyvo skrandžio vėžio gydymo optimizavimas Lietuvos populiacijoje. Tradicinio chirurginio ir minimaliai invazyvių gydymo metodų palyginimas

Author: Baušys, Rimantas and Strupas, Kęstutis
Subjects: Gastric cancer, surgery, minimally invasive, treatment
Abstract: Gastric cancer remains one of the most prevalent cancers worldwide. Surgical resection remains main and only potentially curative treatment option for it. However, surgery is associated with significant morbidity and mortality, especially in elderly patients. Clinical and pathological criteria were determined in Japan to identify early gastric cancer cases with negligible risk of lymph node metastasis. Therefore, new technique – endoscopic resection of the tumor were adopted to clinical practice. This method is widely adopted in Asia, although, not in Western countries. The purpose of this study was to determine the risk factors for lymph node metastasis in Lithuanian population, which can be considered as Western type, also, to determine if endoscopic resection is acceptable in non-Asian population. The study results demonstrate the risk factors for lymph node metastasis, the rate of lymph node metastasis in early gastric cancer which meets the standard and expanded criteria for endoscopic resection. Also, the risk of standard surgical treatment and compares surgery with endoscopic resection regarding short- and longterm results. The conclusions of the study confirm the safety of endoscopic resection for early gastric cancer in the Lithuanian population. This is the first study comparing surgery and endoscopic resection for early gastric cancer in the Western population.
Published: 2019

34. The role of intraoperative neurostimulation using laryngeal palpation and intraoperative laryngeal ultrasound in optimizing the safety of thyroidectomy

Author: Rybakovas, Andrius and Strupas, Kęstutis
Subjects: thyroid surgery, recurrent laryngeal nerve, vocal cord palsy, laryngeal ultrasound
Abstract: Recurrent laryngeal nerve (RLN) injury is one of the major complications related to thyroid surgery. Bilateral laryngeal nerve injury is a particularly pressing concern for a surgeon as it can inflict such serious ill effects as breathing difficulties, reintubation, tracheostomy or even death. Injury identification intraoperatively is crucial, because it can change the operative strategy: the operation on the second side can be canceled, two-stage thyroidectomy planned and bilateral nerve injury avoided. Only some kind of intraoperative neural testing can be relied on to indicate the function of the RLN, as information on neuropraxic nerve injury is missing through visual assessment alone. The main objective of the prospective cohort study was to determine the reliability of intraoperative neurostimulation using laryngeal palpation and intraoperative laryngeal ultrasound for evaluating the RLN functional status during thyroid surgery. The intraoperative laryngeal ultrasound has never been tested in the intraoperative setting, and the validity of the method was not documented before our study was conducted. Only those patients who had no evidence of RLN palsy were enrolled in the study and underwent thyroid surgery. Neurostimulation combined with laryngeal ultrasonography and laryngeal palpation was performed intraoperatively to evaluate recurrent laryngeal nerve functional status. Recurrent laryngeal nerve injury was confirmed by laryngoscopy, which was performed on the first postoperative day and considered to be the gold standard method. Sensitivity, specificity, positive and negative predictive values, and accuracy were calculated for both methods. Our study demonstrated that both methods are effective for intraoperative RLN functional status evaluation. There is no statistically significant difference between the results obtained by both methods. The visualization rate of the intraoperative laryngeal ultrasound is 100%. Both methods can be used intraoperatively based on the individual preference.
Published: 2019

35. Intraoperacinės palpacinės neurostimuliacijos ir gerklų sonoskopijos reikšmė optimizuojant tiroidektomijos saugumą

Author: Rybakovas, Andrius and Strupas, Kęstutis
Subjects: thyroid surgery, recurrent laryngeal nerve, vocal cord palsy, laryngeal ultrasound
Abstract: Recurrent laryngeal nerve (RLN) injury is one of the major complications related to thyroid surgery. Bilateral laryngeal nerve injury is a particularly pressing concern for a surgeon as it can inflict such serious ill effects as breathing difficulties, reintubation, tracheostomy or even death. Injury identification intraoperatively is crucial, because it can change the operative strategy: the operation on the second side can be canceled, two-stage thyroidectomy planned and bilateral nerve injury avoided. Only some kind of intraoperative neural testing can be relied on to indicate the function of the RLN, as information on neuropraxic nerve injury is missing through visual assessment alone. The main objective of the prospective cohort study was to determine the reliability of intraoperative neurostimulation using laryngeal palpation and intraoperative laryngeal ultrasound for evaluating the RLN functional status during thyroid surgery. The intraoperative laryngeal ultrasound has never been tested in the intraoperative setting, and the validity of the method was not documented before our study was conducted. Only those patients who had no evidence of RLN palsy were enrolled in the study and underwent thyroid surgery. Neurostimulation combined with laryngeal ultrasonography and laryngeal palpation was performed intraoperatively to evaluate recurrent laryngeal nerve functional status. Recurrent laryngeal nerve injury was confirmed by laryngoscopy, which was performed on the first postoperative day and considered to be the gold standard method. Sensitivity, specificity, positive and negative predictive values, and accuracy were calculated for both methods. Our study demonstrated that both methods are effective for intraoperative RLN functional status evaluation. There is no statistically significant difference between the results obtained by both methods. The visualization rate of the intraoperative laryngeal ultrasound is 100%. Both methods can be used intraoperatively based on the individual preference.
Published: 2019

36. Arterijų standumo ir kitų biožymenų prognostinė reikšmė vertinant kraujagyslių remodeliaciją ir kardiovaskulinę riziką tarp pakaitine inkstų terapija gydomų pacientų

Author: Laučytė-Cibulskienė, Agnė, Miglinas, Marius, and Strupas, Kęstutis
Subjects: arterial stiffness, chronic kidney disease, kidney transplantation, pulse wave velocity, aortic arch calcification
Abstract: The crosstalk between cardiovascular system and kidney is very complex. Vascular remodeling in kidney failure eventually leads to arterial stiffening and promotes accelerated arterial aging. Traditional cardiovascular risk factors cannot fully explain the high prevalence of cardiovascular disease in chronic kidney disease (CKD). Arterial stiffening is a variable which significantly improves the cardiovascular risk prediction and represents the overall status of elastic and muscular arteries in CKD. The aim of this work was to establish the evolution and clinical significance of different arterial stiffness parameters in predicting vascular calcification and cardiovascular events in end-stage renal disease and after kidney transplantation. A single-center observational longitudinal study from December 2014 to July 2017 was accomplished. One part of the study focused on CKD stage 5D patients (n=101), the other – on patients before and after kidney transplantation (n=37). All selected participants had no previous history of cardiovascular (CVE), cerebrovascular events or peripheral artery disease. Study subjects were interviewed underwent blood tests, chest X-ray and PWV measurements at the beginning of the study and after different observation periods. During two years follow-up we observed that calculated PWV ratio can predict the extent of vascular calcification and is not associated with CVE in chronic dialysis patients; hemodialysis is related to aortic stiffness progression and brachial arterial stiffness regression; and aortic but not brachial arterial stiffness decrease follows successful kidney transplantation.
Published: 2018

37. Arterial stiffness and other biomarkers as vascular remodeling and cardiovascular risk predictors in patients on renal replacement therapy

Author: Laučytė-Cibulskienė, Agnė, Miglinas, Marius, and Strupas, Kęstutis
Subjects: arterial stiffness, chronic kidney disease, kidney transplantation, pulse wave velocity, aortic arch calcification
Abstract: The crosstalk between cardiovascular system and kidney is very complex. Vascular remodeling in kidney failure eventually leads to arterial stiffening and promotes accelerated arterial aging. Traditional cardiovascular risk factors cannot fully explain the high prevalence of cardiovascular disease in chronic kidney disease (CKD). Arterial stiffening is a variable which significantly improves the cardiovascular risk prediction and represents the overall status of elastic and muscular arteries in CKD. The aim of this work was to establish the evolution and clinical significance of different arterial stiffness parameters in predicting vascular calcification and cardiovascular events in end-stage renal disease and after kidney transplantation. A single-center observational longitudinal study from December 2014 to July 2017 was accomplished. One part of the study focused on CKD stage 5D patients (n=101), the other – on patients before and after kidney transplantation (n=37). All selected participants had no previous history of cardiovascular (CVE), cerebrovascular events or peripheral artery disease. Study subjects were interviewed underwent blood tests, chest X-ray and PWV measurements at the beginning of the study and after different observation periods. During two years follow-up we observed that calculated PWV ratio can predict the extent of vascular calcification and is not associated with CVE in chronic dialysis patients; hemodialysis is related to aortic stiffness progression and brachial arterial stiffness regression; and aortic but not brachial arterial stiffness decrease follows successful kidney transplantation.
Published: 2018

38. BRAF V600E mutacijos ir citomorfologinių požymių reikšmė papilinio skydliaukės vėžio diagnostikos optimizavimui

Author: Beiša, Augustas and Strupas, Kęstutis
Subjects: endocrine system diseases, Papillary thyroid cancer, BRFA V600E, Thyroid cancer
Abstract: Thyroid nodules are detected in about 50% of adults who live in regions deficient in iodine. Although thyroid cancer is the most common oncological endocrine disorder, only 5% of the thyroid nodules are malignant. Papillary thyroid cancer (PTC) comprises 85 to 90% of cases of all histological types of thyroid cancer. Although PTC has a slow progression and good survival rates, 20% to 30% of patients have localized disease recurrences or distant metastases and about 1% of patients die from this disease. A fine needle aspiration biopsy (FNA) performed under ultrasound (US) guidance and a cytological examination of nodules remains the gold standard for the differential diagnostics of thyroid cancer. However, due to a well-differentiated nature of most thyroid cancers, 10 to 26% of samples are ascribed to cytologically indeterminate diagnostic categories (categories III, IV, V, according to the Bethesda system). In order to determine the exact diagnosis, diagnostic surgery is usually proposed for these patients; however, a histological examination of resected tissues confirms the diagnosis of thyroid cancer in only one-third of patients. In the absence of reliable preoperative diagnostic criteria, there is a risk of general, surgical intervention-related and thyroid surgery-specific complications including temporary or permanent vocal cord paralysis and temporary or permanent decrease in blood calcium levels. After surgery, replacement therapy with thyroxine is usually required for the rest of patients’ lives. Besides, psychological discomfort due to a 4 to 6 cm long scar in the neck may be experienced. These causes lead to high socioeconomic costs and encourage to search for new options of diagnostics and prediction that could potentially optimize patient selection for surgical treatment. Molecular genetic tests are among the most promising methods for the diagnostics of thyroid cancer and for the predictions of the disease course. The first works on the impact of BRAF mutations in oncological diseases were performed in studies of skin, colon and lung tumors. The link between BRAF mutations and PTC was confirmed in publications in 2003. A high V400E mutation specificity for PTC was noticed at that time. Therefore, Xing et al. had proposed BRAF V600E mutation testing for presurgical PTC diagnostics already in 2004. Although many publications on the applications of BRAF V600E mutation testing for PTC diagnostics and prognostication have appeared since that time, published data and recommendations remain controversial. Since the prevalence of BRAF V600E mutation in PTC tumors ranges from 30 to 80% depending on the geographical region, it can be stated that only the detection of mutation prevalence in the population under study can determine the applicability of this testing in clinical practice. The prevalence of BRAF V600E mutations in PTC in Lithuania has not been investigated so far.
Published: 2018

39. The significance of the BRAF V600E mutation and the cytomorphological features for the optimization of papillary thyroid cancer diagnostics

Author: Beiša, Augustas and Strupas, Kęstutis
Subjects: endocrine system diseases, Papillary thyroid cancer, BRFA V600E, Thyroid cancer
Abstract: Thyroid nodules are detected in about 50% of adults who live in regions deficient in iodine. Although thyroid cancer is the most common oncological endocrine disorder, only 5% of the thyroid nodules are malignant. Papillary thyroid cancer (PTC) comprises 85 to 90% of cases of all histological types of thyroid cancer. Although PTC has a slow progression and good survival rates, 20% to 30% of patients have localized disease recurrences or distant metastases and about 1% of patients die from this disease. A fine needle aspiration biopsy (FNA) performed under ultrasound (US) guidance and a cytological examination of nodules remains the gold standard for the differential diagnostics of thyroid cancer. However, due to a well-differentiated nature of most thyroid cancers, 10 to 26% of samples are ascribed to cytologically indeterminate diagnostic categories (categories III, IV, V, according to the Bethesda system). In order to determine the exact diagnosis, diagnostic surgery is usually proposed for these patients; however, a histological examination of resected tissues confirms the diagnosis of thyroid cancer in only one-third of patients. In the absence of reliable preoperative diagnostic criteria, there is a risk of general, surgical intervention-related and thyroid surgery-specific complications including temporary or permanent vocal cord paralysis and temporary or permanent decrease in blood calcium levels. After surgery, replacement therapy with thyroxine is usually required for the rest of patients’ lives. Besides, psychological discomfort due to a 4 to 6 cm long scar in the neck may be experienced. These causes lead to high socioeconomic costs and encourage to search for new options of diagnostics and prediction that could potentially optimize patient selection for surgical treatment. Molecular genetic tests are among the most promising methods for the diagnostics of thyroid cancer and for the predictions of the disease course. The first works on the impact of BRAF mutations in oncological diseases were performed in studies of skin, colon and lung tumors. The link between BRAF mutations and PTC was confirmed in publications in 2003. A high V400E mutation specificity for PTC was noticed at that time. Therefore, Xing et al. had proposed BRAF V600E mutation testing for presurgical PTC diagnostics already in 2004. Although many publications on the applications of BRAF V600E mutation testing for PTC diagnostics and prognostication have appeared since that time, published data and recommendations remain controversial. Since the prevalence of BRAF V600E mutation in PTC tumors ranges from 30 to 80% depending on the geographical region, it can be stated that only the detection of mutation prevalence in the population under study can determine the applicability of this testing in clinical practice. The prevalence of BRAF V600E mutations in PTC in Lithuania has not been investigated so far.
Published: 2018

40. The value of inflammation markers in early acute pancreatitis course prediction: the results of prospective multicenter cohort study

Author: Karpavičius, Andrius and Strupas, Kęstutis
Subjects: acute pancreatitis, prognosis, adipokines
Abstract: The mortality rate of patients with severe acute pancreatitis (SAP) can reach up to 30%. Early and appropriate treatment will progress in reducing rates of SAP complications. The main problem remains, that neither prognostic scores nor single predictors can’t accurately predict the disease course and complications during the first hours of hospitalization. Perhaps, the least studied group of predictors are adipokines. Adipokines are cytokines produced in white adipose tissue as well as in peripancreatic fat and involved in inflammatory response. Increase of fatty tissue due to obesity is associated with the amplified systemic inflammatory response in AP. It is hypothesized that peripancreatic necrosis can cause the massive release of adipokines into the patient’s bloodstream, so adipokines can serve as predictors of clinical course and complications of acute pancreatitis. Furthermore, in 2012 the Atlanta classification of AP was revisited and new form – moderate severity AP – was indentified. Therefore the criteria of SAP became more stringent and the cut off values of all prognostic markers must be recalculated. The aim of the dissertation is to evaluate the prognostic usefulness of inflammation markers and compare it with existing prognostic systems for AP course and complications. The study enrolled 102 of AP patients. According to the revisited Atlanta classification 27 (26.5%) of all patients were classified as mild, 55 (53.9%) as moderate severity and 20 (19.6%) as SAP. It was found, that higher BMI and the peripancreatic necrosis are associated with more severe AP cases. Resistin, IL-6 and BISAP score were found to be the early markers of SAP. Only BISAP score was an early predictor of necrosis, needs for interventions and mortality.
Published: 2015

41. Uždegimo žymenų reikšmė ankstyvam ūminio pankreatito eigos prognozavimui: perspektyvinio daugiacentrio kohortinio tyrimo rezultatai

Author: Karpavičius, Andrius and Strupas, Kęstutis
Subjects: Acute pancreatitis, prognosis, adipokines
Abstract: The mortality rate of patients with severe acute pancreatitis (SAP) can reach up to 30%. Early and appropriate treatment will progress in reducing rates of SAP complications. The main problem remains, that neither prognostic scores nor single predictors can’t accurately predict the disease course and complications during the first hours of hospitalization. Perhaps, the least studied group of predictors are adipokines. Adipokines are cytokines produced in white adipose tissue as well as in peripancreatic fat and involved in inflammatory response. Increase of fatty tissue due to obesity is associated with the amplified systemic inflammatory response in AP. It is hypothesized that peripancreatic necrosis can cause the massive release of adipokines into the patient’s bloodstream, so adipokines can serve as predictors of clinical course and complications of acute pancreatitis. Furthermore, in 2012 the Atlanta classification of AP was revisited and new form – moderate severity AP – was indentified. Therefore the criteria of SAP became more stringent and the cut off values of all prognostic markers must be recalculated. The aim of the dissertation is to evaluate the prognostic usefulness of inflammation markers and compare it with existing prognostic systems for AP course and complications. The study enrolled 102 of AP patients. According to the revisited Atlanta classification 27 (26.5%) of all patients were classified as mild, 55 (53.9%) as moderate severity and 20 (19.6%) as SAP. It was found, that higher BMI and the peripancreatic necrosis are associated with more severe AP cases. Resistin, IL-6 and BISAP score were found to be the early markers of SAP. Only BISAP score was an early predictor of necrosis, needs for interventions and mortality.
Published: 2015

42. Comparison of three tourniquet application methods in primary total knee arthroplasty surgery

Author: Kvederas, Giedrius and Strupas, Kęstutis
Subjects: musculoskeletal diseases, surgical procedures, operative, total knee arthroplasty, tourniquet, blood loss, functional outcomes, individualized fluid therapy
Abstract: The optimal timing of pneumatic lower limb tourniquet application during primary elective total knee arthroplasty surgery (TKA) is a matter of debate. 132 patients who undergo TKA were prospectively randomized into one of the 4 groups, and 120 of these patients completed the study. The tourniquet was inflated just before incision and deflated after the hardening of the cement for 30 patients (Group 1), it was inflated just before cement application and deflated after its hardening for another 30 patients (Group 2), and it was inflated before incision and deflated after the last suture of the skin for a further 30 patients (Group 3). The Group 4 received fluids at the discretion of an attending physician (standard of care). Group 1, 2 and 3 were given the same regimen but it was supplemented by a revGDT (revised Goal directed therapy) algorithm before the TKA and 24 h later. Fit-to-discharge criteria and six methods for calculating estimated blood loss were used. The estimated blood loss in Group 2 was higher than in Group 1 and 3. Group 1 was better fit to discharge than Group 3 and Group 4. Inflation of an automatic pneumatic lower limb tourniquet before skin incision and its deflation after hardening of cement tends to give better outcomes in TKA patients during six postoperative days. The estimated blood loss was highest when the tourniquet was inflated just before cement application and deflated after its hardening. Perioperative revGDT enhanced recovery after TKA.
Published: 2015

43. Value of computerized inhibitory control test and blood tests in minimal hepatic encephalopathy diagnosis

Author: Savlan, Ilona, IRNIUS, ALGIMANTAS, KUPČINSKAS, LIMAS, JATUŽIS, DALIUS, JONAITIS, LAIMAS VIRGINIJUS, SPEIČIENĖ, DANUTĖ MARIJA, AMBROZAITIS, ARVYDAS, KONDRACKIENĖ, JŪRATĖ, VALANTINAS, JONAS, STRUPAS, KĘSTUTIS, and Vilnius University
Subjects: minimal hepatic encephalopathy, inhibitory control test, IL-6, PHES battery, PHES rinkinys, parasitic diseases, Minimal hepatic encephalopathy, Medicine, Inhibicinis kontrolės testas, Inhibitory control test, Minimali hepatinė encefalopatija
Abstract: Darbo tikslas – nustatyti kompiuterizuoto inhibicinio kontrolės testo (IKT), IL-6, amoniako bei įprastinių kraujo rodiklių vertę diagnozuojant kognityvinius sutrikimus sergantiems lėtinėmis kepenų ligomis. Darbo uždaviniai: nustatyti kognityvinių sutrikimų dažnį, galimus rizikos veiksnius, palyginti IKT ir kraujo testų rezultatus lėtinio hepatito ir kepenų cirozės grupėse; nustatyti IKT bei IL-6, įprastinių kraujo testų vertę minimaliai hepatinei encefalopatijai (MHE). Iki šiol netirta ar pacientai, sergantys lėtiniu hepatitu ir kognityviniais sutrikimais, neturi analogiškų IKT rodiklių pakitimų, IL-6 koncentracijos padidėjimo kaip sergantieji kepenų ciroze ir MHE. Netirta kokie kraujo ar IKT rodikliai kognityvinius sutrikimus prognozuoja geriausia. Į tyrimą įtraukti 62 sergantieji kepenų ciroze be hepatinės encefalopatijos, 73 lėtiniu hepatitu bei 53 sveiki asmenys. Tą pačią dieną buvo atliekami kraujo tyrimai, psichometriniai testai ir IKT. Lėtinio hepatito grupėje kognityviniai sutrikimai nustatyti 54,8 %, о kepenų cirozės grupėje MHE ¬ 71,0 % tiriamųjų asmenų. Kognityvinius sutrikimus predisponuoja trumpesnė mokymosi trukmė, fibrozės laipsnis, dvigubas etiologinis veiksnys, amžius ir lytis įtakos neturi. Lėtinio hepatito grupėje kognityviniai sutrikimai koreliuoja su IKT rodikliais ir kepenų fermentų koncentracijos padidėjimu, o kepenų cirozių grupėje su IKT rodikliais ir IL-6 koncentracija kraujyje. Išvados: Kognityvinius sutrikimus sergant lėtiniu hepatitu ar... [toliau žr. visą tekstą] The aim of the study was to ascertain a value of computerized inhibitory control test (ICT), routine blood tests, peripheral blood ammonia and IL-6 concentration for diagnosis of cognitive disorders in patients with chronic liver diseases. Tasks: to assess a frequency of cognitive impairments and associated risk factors and to compare ICT and blood tests results in chronic hepatitis and cirrhotic patients; to ascertain ICT, IL-6 and routine blood tests values for diagnosis of minimal hepatic encephalopathy (MHE). Until now there were no studies performed whether chronic hepatitis patients with cognitive disorders have analogous ICT, IL-6 and other tests abnormalities as cirrhotic patients with MHE. It has not been studied which ICT and other tests results predict best the cognitive disorders in such patients. 62 cirrhotic patients without overt hepatic encephalopathy, 73 chronic hepatitis and 53 healthy individuals were enrolled. On the same day blood tests, psychometric and ICT tests were performed by every participant. Cognitive disorders were detected in 54,8% of chronic hepatitis patients. In cirrhotic patients MHE was found in 71,0%. Cognitive disorders predispose shorter study time, the fibrosis score, double etiologic factor, while age and gender has no influence. In chronic hepatitis patients the cognitive impairments correlate with ICT and elevated liver enzymes. In cirrhotic patients cognitive disorders correlate with ICT and IL-6 concentration. Conclusion: the... [to full text]
Published: 2014

44. Kompiuterizuoto inhibicinio kontrolės ir laboratorinių testų vertė nustatant minimalią hepatinę encefalopatiją

Author: Savlan, Ilona, IRNIUS, ALGIMANTAS, KUPČINSKAS, LIMAS, JATUŽIS, DALIUS, JONAITIS, LAIMAS VIRGINIJUS, SPEIČIENĖ, DANUTĖ MARIJA, AMBROZAITIS, ARVYDAS, KONDRACKIENĖ, JŪRATĖ, VALANTINAS, JONAS, STRUPAS, KĘSTUTIS, and Vilnius University
Subjects: minimal hepatic encephalopathy, inhibitory control test, IL-6, PHES battery, PHES rinkinys, parasitic diseases, Minimal hepatic encephalopathy, Medicine, Inhibicinis kontrolės testas, Inhibitory control test, Minimali hepatinė encefalopatija
Abstract: The aim of the study was to ascertain a value of computerized inhibitory control test (ICT), routine blood tests, peripheral blood ammonia and IL-6 concentration for diagnosis of cognitive disorders in patients with chronic liver diseases. Tasks: to assess a frequency of cognitive impairments and associated risk factors and to compare ICT and blood tests results in chronic hepatitis and cirrhotic patients; to ascertain ICT, IL-6 and routine blood tests values for diagnosis of minimal hepatic encephalopathy (MHE). Until now there were no studies performed whether chronic hepatitis patients with cognitive disorders have analogous ICT, IL-6 and other tests abnormalities as cirrhotic patients with MHE. It has not been studied which ICT and other tests results predict best the cognitive disorders in such patients. 62 cirrhotic patients without overt hepatic encephalopathy, 73 chronic hepatitis and 53 healthy individuals were enrolled. On the same day blood tests, psychometric and ICT tests were performed by every participant. Cognitive disorders were detected in 54,8% of chronic hepatitis patients. In cirrhotic patients MHE was found in 71,0%. Cognitive disorders predispose shorter study time, the fibrosis score, double etiologic factor, while age and gender has no influence. In chronic hepatitis patients the cognitive impairments correlate with ICT and elevated liver enzymes. In cirrhotic patients cognitive disorders correlate with ICT and IL-6 concentration. Conclusion: the... [to full text] Darbo tikslas – nustatyti kompiuterizuoto inhibicinio kontrolės testo (IKT), IL-6, amoniako bei įprastinių kraujo rodiklių vertę diagnozuojant kognityvinius sutrikimus sergantiems lėtinėmis kepenų ligomis. Darbo uždaviniai: nustatyti kognityvinių sutrikimų dažnį, galimus rizikos veiksnius, palyginti IKT ir kraujo testų rezultatus lėtinio hepatito ir kepenų cirozės grupėse; nustatyti IKT bei IL-6, įprastinių kraujo testų vertę minimaliai hepatinei encefalopatijai (MHE). Iki šiol netirta ar pacientai, sergantys lėtiniu hepatitu ir kognityviniais sutrikimais, neturi analogiškų IKT rodiklių pakitimų, IL-6 koncentracijos padidėjimo kaip sergantieji kepenų ciroze ir MHE. Netirta kokie kraujo ar IKT rodikliai kognityvinius sutrikimus prognozuoja geriausia. Į tyrimą įtraukti 62 sergantieji kepenų ciroze be hepatinės encefalopatijos, 73 lėtiniu hepatitu bei 53 sveiki asmenys. Tą pačią dieną buvo atliekami kraujo tyrimai, psichometriniai testai ir IKT. Lėtinio hepatito grupėje kognityviniai sutrikimai nustatyti 54,8 %, о kepenų cirozės grupėje MHE ¬ 71,0 % tiriamųjų asmenų. Kognityvinius sutrikimus predisponuoja trumpesnė mokymosi trukmė, fibrozės laipsnis, dvigubas etiologinis veiksnys, amžius ir lytis įtakos neturi. Lėtinio hepatito grupėje kognityviniai sutrikimai koreliuoja su IKT rodikliais ir kepenų fermentų koncentracijos padidėjimu, o kepenų cirozių grupėje su IKT rodikliais ir IL-6 koncentracija kraujyje. Išvados: Kognityvinius sutrikimus sergant lėtiniu hepatitu ar... [toliau žr. visą tekstą]
Published: 2014

45. Evaluating the efficacy of intra-articular and perineural analgesia methods for the arthroscopic reconstruction of anterior cruciate ligament of the knee

Author: Švedienė, Saulė, STRUPAS, KĘSTUTIS, TUTKUVIENĖ, JANINA, LESINSKAS, EUGENIJUS, KINDURIS, ŠARŪNAS, MACAS, ANDRIUS, ŠIRVINSKAS, EDMUNDAS, DIDŽIAPETRIENĖ, JANINA, and Vilnius University
Subjects: Perineurinis metodas, Intrasąnarinis, Perioperative analgesia, perioperative analgesia, intra-articular, perineural method, Medicine, Perineural method, Perioperacinė analgezija, Intra-articular
Abstract: Artroskopinė priekinio kryžminio raiščio rekonstrukcija – viena iš dažniausiai atliekamų ortopedinių operacijų. Adekvati skausmo kontrolė yra svarbi siekiant efektyvios ankstyvos reabilitacijos ir gerų funkcinių rezultatų, sutrumpinant gydymo ligoninėje trukmę. Atlikome randomizuotą perspektyvųjį dvigubai aklą placebu kontroliuojamą tyrimą panaudodami intrasąnarinius vaistus (morfiną ir neostigminą), derindami su vienkartine šlauninio nervo blokada. Taip pat tyrėme tęstinį skausmo malšinimą šlaunies perineuriniu kateteriu, taikydami du skirtingus paciento kontroliuojamos analgezijos režimus. Taikėme mažesnę vietinio anestetiko koncentraciją, siekdami selektyvesnės sensorinės blokados, mažesnės paros dozės, mažiau toksinių reakcijų. Tikrinome, ar tęstinis skausmo malšinimas yra veiksmingesnis nei vienkartinė nervo blokada su intrasąnarinėmis analgetikų injekcijomis. Intrasąnarinis morfinas turėjo panašų analgezinį poveikį kaip ir neostigminas paciento krūvio metu per visą tyrimo laiką (48 val.); tačiau neostigminas buvo patikimai efektyvesnis už placebą antrą pooperacinę dieną. Skausmo kontrolė ramybėje ir krūvio metu bei pacientų pasitenkinimas per visą tyrimą buvo geresni perineurinio skausmo malšinimo grupėse negu intrasąnarinėse. Intrasąnarinių grupių pacientų analgezijos efektyvumui priartėjus prie kateterinių grupių, nustatydavome didesnį papildomų analgetikų suvartojimą pirmosiose. Skausmo malšinimas 0,1% bupivakaino infuzija šlaunies perineuriniu kateteriu, taikant... [toliau žr. visą tekstą] Choice of optimal postoperative analgesia technique after anterior crutiate ligament repair remains challenging. Aiming to evaluate and compare the efficacy of intra-articular injection of morphine and neostigmine our prospective randomized clinical study compared pain intensity, consumption of adjunct analgesics and patient satisfaction during 48 postoperative hours in patients who, in addition to spinal block, received a single-shot femoral nerve block followed by the end-of-surgery intra-articular injection of morphine, neostigmine or placebo. Additionally, the former two were compared with continuous femoral nerve block with postoperative patient controlled analgesia infusion pump containing 0.1 % bupivacaine preset in 2 different regimens: with or without basal infusion. Our results show that there was only a single difference among intra-articular groups found on the 2nd postoperative day: a significantly better pain control at motion in neostigmine group than in the placebo group. There was no additive analgesic effect of i/a morphine. Also, we observed a significantly better pain control and patient satisfaction in continuous femoral perineural block PCA groups during the whole trial. There was a significant prevalence of the PCA analgesia regimen which implies the preset basal rate of 0.1% bupivacaine: a 5 ml bolus with a lockout period 30 min and basal infusion 5 ml/h.
Published: 2013

46. Bendrosios ir kombinuotos anestezijos metodų palyginimas pacientams, kuriems atliekamos storosios žarnos laparoskopinės operacijos

Author: Gasiūnaitė, Diana, STRUPAS, KĘSTUTIS, TUTKUVIENĖ, JANINA, DIDŽIAPETRIENĖ, JANINA, KINDURIS, ŠARŪNAS, ŠIRVINSKAS, EDMUNDAS, MACAS, ANDRIUS, IVAŠKEVIČIUS, JUOZAS, and Vilnius University
Subjects: Stresinis atsakas, colorectal surgery, epidural analgesia, combined anesthesia, cortisol level, stress response, Laparoscopic colorectal surgery, Combined anesthesia, Epiduralinė analgezija, Epidural analgesia, Cortisol level, Stress response, Kortizolio kiekis, Medicine, Kombinuota anestezija, Laparoskopinė kolorektalinė chirurgija
Abstract: The doctoral dissertation analyses and compares general endotracheal and combined endotracheal epidural anesthesia’s impact on organ systems and describes the systems parameters in laparoscopic colorectal surgery. Comparing two perioperative analgesia techniques used in laparoscopic colorectal surgery the hemodynamic and respiratory parameters trends; the impact of anesthesia and postoperative analgesia methods on patients’ tracheal extubation time, intestinal motility recovery rate, duration of hospitalization and inflammatory response have been determined. Laparoscopic colorectal resection, even being a minimally invasive technique for laparoscopic surgery, stimulates the body's response to stress and pro-inflammatory mediator’s secretion. Perioperative pain management may also influence the immune response. The doctoral dissertation analyses the impact of epidural analgesia method on the body stress response, investigating variations of cortisol and interleukin-6 levels. The results showed that analgesia and patient satisfaction using epidural analgesia method for perioperative pain management were better. Tracheal extubation time was significantly shorter. Recovery of intestinal motility using epidural analgesia was significant and much prior than using intravenous analgesia. The use of epidural analgesia in laparoscopic colorectal surgery caused less stress response – less cortisol levels increase. It has not showed the increase in number of complications. Disertacijoje analizuojama ir lyginama bendrosios endotrachėjinės ir kombinuotos endotrachėjinės epiduralinės anestezijos įtaka atskiroms organų sistemoms ir tas sistemas apibūdinantiems rodikliams laparoskopinių kolorektalinių operacijų metu. Darbe nagrinėjama dviejų perioperacinių skausmo malšinimo būdų įtaka hemodinamikos ir kvėpavimo sistemos parametrų kitimo tendencijoms, pacientų trachėjos ekstubacijos laikui, žarnyno motorikos atsinaujinimo greičiui, hospitalizacijos trukmei bei organizmo uždegiminiam atsakui. Laparoskopinės storosios žarnos rezekcinės operacijos, net ir būdamos minimaliai invazinės dėl laparoskopinės operacijos technikos, sužadina stresinį organizmo atsaką bei uždegimo mediatorių išskyrimą. Perioperacinis skausmo valdymas taip pat gali daryti įtaką imuniniam atsakui. Disertacijoje nagrinėjama epiduralinės analgezijos metodo įtaka organizmo stresiniam atsakui tiriant kortizolio kiekio kitimus ir interleukino-6, kaip vieno pagrindinių uždegimą skatinančių citokinų, koncentracijos kitimą taikant epiduralinę analgezijos metodiką. Gauti rezultatai parodė, kad analgezijai pasitelkiant epiduralinį skausmo malšinimo metodą, perioperacinis pacientų skausmo valdymas ir pasitenkinimas yra geresnis, trachėjos ekstubacijos laikas patikimai trumpesnis, žarnyno peristaltikos atsitaisymas ankstyvesnis, sukeliamas stresinis organizmo atsakas mažesnis (mažesnis kortizolio koncentracijos padidėjimas) ir nenustatyta komplikacijų padaugėjimo.
Published: 2013

47. Intrasąnarinės ir perineurinės analgezijos metodų veiksmingumo nustatymas atliekant artroskopines kelio priekinio kryžminio raiščio rekonstrukcines operacijas

Author: Švedienė, Saulė, STRUPAS, KĘSTUTIS, TUTKUVIENĖ, JANINA, LESINSKAS, EUGENIJUS, KINDURIS, ŠARŪNAS, MACAS, ANDRIUS, ŠIRVINSKAS, EDMUNDAS, DIDŽIAPETRIENĖ, JANINA, and Vilnius University
Subjects: Perineurinis metodas, Intrasąnarinis, Perioperative analgesia, Medicine, Perineural method, perioperative analgesia, intra-articular, perineural method, Perioperacinė analgezija, Intra-articular
Abstract: Choice of optimal postoperative analgesia technique after anterior crutiate ligament repair remains challenging. Aiming to evaluate and compare the efficacy of intra-articular injection of morphine and neostigmine our prospective randomized clinical study compared pain intensity, consumption of adjunct analgesics and patient satisfaction during 48 postoperative hours in patients who, in addition to spinal block, received a single-shot femoral nerve block followed by the end-of-surgery intra-articular injection of morphine, neostigmine or placebo. Additionally, the former two were compared with continuous femoral nerve block with postoperative patient controlled analgesia infusion pump containing 0.1 % bupivacaine preset in 2 different regimens: with or without basal infusion. Our results show that there was only a single difference among intra-articular groups found on the 2nd postoperative day: a significantly better pain control at motion in neostigmine group than in the placebo group. There was no additive analgesic effect of i/a morphine. Also, we observed a significantly better pain control and patient satisfaction in continuous femoral perineural block PCA groups during the whole trial. There was a significant prevalence of the PCA analgesia regimen which implies the preset basal rate of 0.1% bupivacaine: a 5 ml bolus with a lockout period 30 min and basal infusion 5 ml/h. Artroskopinė priekinio kryžminio raiščio rekonstrukcija – viena iš dažniausiai atliekamų ortopedinių operacijų. Adekvati skausmo kontrolė yra svarbi siekiant efektyvios ankstyvos reabilitacijos ir gerų funkcinių rezultatų, sutrumpinant gydymo ligoninėje trukmę. Atlikome randomizuotą perspektyvųjį dvigubai aklą placebu kontroliuojamą tyrimą panaudodami intrasąnarinius vaistus (morfiną ir neostigminą), derindami su vienkartine šlauninio nervo blokada. Taip pat tyrėme tęstinį skausmo malšinimą šlaunies perineuriniu kateteriu, taikydami du skirtingus paciento kontroliuojamos analgezijos režimus. Taikėme mažesnę vietinio anestetiko koncentraciją, siekdami selektyvesnės sensorinės blokados, mažesnės paros dozės, mažiau toksinių reakcijų. Tikrinome, ar tęstinis skausmo malšinimas yra veiksmingesnis nei vienkartinė nervo blokada su intrasąnarinėmis analgetikų injekcijomis. Intrasąnarinis morfinas turėjo panašų analgezinį poveikį kaip ir neostigminas paciento krūvio metu per visą tyrimo laiką (48 val.); tačiau neostigminas buvo patikimai efektyvesnis už placebą antrą pooperacinę dieną. Skausmo kontrolė ramybėje ir krūvio metu bei pacientų pasitenkinimas per visą tyrimą buvo geresni perineurinio skausmo malšinimo grupėse negu intrasąnarinėse. Intrasąnarinių grupių pacientų analgezijos efektyvumui priartėjus prie kateterinių grupių, nustatydavome didesnį papildomų analgetikų suvartojimą pirmosiose. Skausmo malšinimas 0,1% bupivakaino infuzija šlaunies perineuriniu kateteriu, taikant... [toliau žr. visą tekstą]
Published: 2013

48. Comparison of general and combined anesthesia during laparoscopic colorectal surgery

Author: Gasiūnaitė, Diana, STRUPAS, KĘSTUTIS, TUTKUVIENĖ, JANINA, DIDŽIAPETRIENĖ, JANINA, KINDURIS, ŠARŪNAS, ŠIRVINSKAS, EDMUNDAS, MACAS, ANDRIUS, IVAŠKEVIČIUS, JUOZAS, and Vilnius University
Subjects: Stresinis atsakas, Epiduralinė analgezija, Combined anesthesia, Colorectal surgery, Epidural analgesia, Kolorektalinės operacijos, Cortisol level, Stress response, Kortizolio kiekis, Medicine, Kombinuota anestezija, laparoscopic colorectal surgery, epidural analgesia, combined anesthesia, cortisol level, stress response
Abstract: Disertacijoje analizuojama ir lyginama bendrosios endotrachėjinės ir kombinuotos endotrachėjinės epiduralinės anestezijos įtaka atskiroms organų sistemoms ir tas sistemas apibūdinantiems rodikliams laparoskopinių kolorektalinių operacijų metu. Darbe nagrinėjama dviejų perioperacinių skausmo malšinimo būdų įtaka hemodinamikos ir kvėpavimo sistemos parametrų kitimo tendencijoms, pacientų trachėjos ekstubacijos laikui, žarnyno motorikos atsinaujinimo greičiui, hospitalizacijos trukmei bei organizmo uždegiminiam atsakui. Laparoskopinės storosios žarnos rezekcinės operacijos, net ir būdamos minimaliai invazinės dėl laparoskopinės operacijos technikos, sužadina stresinį organizmo atsaką bei uždegimo mediatorių išskyrimą. Perioperacinis skausmo valdymas taip pat gali daryti įtaką imuniniam atsakui. Disertacijoje nagrinėjama epiduralinės analgezijos metodo įtaka organizmo stresiniam atsakui tiriant kortizolio kiekio kitimus ir interleukino-6, kaip vieno pagrindinių uždegimą skatinančių citokinų, koncentracijos kitimą taikant epiduralinę analgezijos metodiką. Gauti rezultatai parodė, kad analgezijai pasitelkiant epiduralinį skausmo malšinimo metodą, perioperacinis pacientų skausmo valdymas ir pasitenkinimas yra geresnis, trachėjos ekstubacijos laikas patikimai trumpesnis, žarnyno peristaltikos atsitaisymas ankstyvesnis, sukeliamas stresinis organizmo atsakas mažesnis (mažesnis kortizolio koncentracijos padidėjimas) ir nenustatyta komplikacijų padaugėjimo. The doctoral dissertation analyses and compares general endotracheal and combined endotracheal epidural anesthesia’s impact on organ systems and describes the systems parameters in laparoscopic colorectal surgery. Comparing two perioperative analgesia techniques used in laparoscopic colorectal surgery the hemodynamic and respiratory parameters trends; the impact of anesthesia and postoperative analgesia methods on patients’ tracheal extubation time, intestinal motility recovery rate, duration of hospitalization and inflammatory response have been determined. Laparoscopic colorectal resection, even being a minimally invasive technique for laparoscopic surgery, stimulates the body's response to stress and pro-inflammatory mediator’s secretion. Perioperative pain management may also influence the immune response. The doctoral dissertation analyses the impact of epidural analgesia method on the body stress response, investigating variations of cortisol and interleukin-6 levels. The results showed that analgesia and patient satisfaction using epidural analgesia method for perioperative pain management were better. Tracheal extubation time was significantly shorter. Recovery of intestinal motility using epidural analgesia was significant and much prior than using intravenous analgesia. The use of epidural analgesia in laparoscopic colorectal surgery caused less stress response – less cortisol levels increase. It has not showed the increase in number of complications.
Published: 2013

49. Evaluation of the causes, diagnostic criteria, surgical treatment and follow-up results of ovarian torsion in children

Author: Geimanaitė, Lina, TUTKUVIENĖ, JANINA, STRUPAS, KĘSTUTIS, TAMOŠIŪNAS, ALGIRDAS EDVARDAS, BARAUSKAS, VIDMANTAS, CICĖNAS, SAULIUS, SLADKEVIČIUS, POVILAS, VERKAUSKAS, GILVYDAS, TRAINAVIČIUS, KĘSTUTIS, and Vilnius University
Subjects: Surgical treatment, Kiaušidės užsisukimas, ovarian torsion, children, surgical treatment, Chirurginis gydymas, Medicine, Ovarian torsion, Vaikų, Children
Abstract: Ovarian torsion is a rare children’s acute abdominal disease which is difficult to diagnose and there is no consensus among scientists how to treat it. This is the first scientific research in Lithuania which analyses causes, optimal diagnostic criteria, the strategy, methods of surgical treatment and follow-up results of ovarian torsion in children. This is the largest research of the follow-up results of the conservative surgical treatment in the world. It was identified during the research that as many as 54.7% of the causes of ovarian torsion were congenital anatomical. In the case of 45.3% of the patients ovarian torsion was caused by pathological derivatives. In patients before menarche there were statistically significantly more mature teratomas (p=0.03). No specific symptoms of ovarian torsion in children were identified. Prior to the surgery, ultrasonography showed that the twisted ovary was on average 21.48 (17.06) times larger than the healthy ovary. Leukocytosis and ovarian blood flow disorders were statistically significantly more common in the case of ovarectomy. None of the girls who underwent detorsion with the ovary left in the abdominal cavity had thromboembolism or peritonitis; no malignant tumour was detected in any girl. According to the histopathological findings, no necrosis was detected in 14 (82.35%) removed ovaries, therefore they could be salvaged. Normal ovarian anatomy and folliculogenesis were retained in 95.24% of girls and women who were... [to full text] Kiaušidžių užsisukimas – reta ūminė vaikų pilvo organų liga, kurios diagnostika sudėtinga, o dėl gydymo mokslininkai vis dar nesutaria. Tai pirmasis Lietuvoje mokslinis tyrimas, analizuojantis vaikų kiaušidžių užsisukimo priežastis, optimalius diagnostikos kriterijus, chirurginio gydymo taktiką ir metodus bei atokiuosius rezultatus. Šis atokiųjų konservatyvaus chirurginio gydymo rezultatų tyrimas yra didžiausias pasaulyje. Darbe nustatyta, kad 54,7 % kiaušidės užsisukimo priežasčių buvo įgimtos anatominės; 45,3 % ligonių kiaušidė užsisuko dėl patologinių darinių. Ligonėms iki menarchės statistiškai patikimai dažniau rasta brandžių teratomų (p=0,03). Specifinių vaikų kiaušidės užsisukimo simptomų ir požymių nenustatyta. Iki operacijos, tiriant echoskopu, užsisukusi kiaušidė buvo didesnė nei sveikoji vidutiniškai 21,48 (17,06) karto. Leukocitozė ir kiaušidės kraujotakos sutrikimai statistiškai patikimai dažnesni mergaitėms, kurioms kiaušidė pašalinta. Nė vienai mergaitei, kuriai kiaušidė buvo atsukta ir palikta pilvo ertmėje, nebuvo trombembolijos ir peritonito, nė vienai nerasta piktybinio naviko. Remiantis patologijos histologijos tyrimais, nustatyta, kad 14-oje (82,35 %) pašalintų kiaušidžių nekrozės ir patologinių darinių nebuvo, todėl jos galėjo būti išsaugotos. Patikrintų 95,24 % mergaičių ir moterų atsuktos kiaušidės anatomija ir folikulogenezė išliko normali.
Published: 2012

50. Vaikų kiaušidžių užsisukimo priežasčių, diagnostikos kriterijų, chirurginio gydymo ir atokiųjų rezultatų vertinimas

Author: Geimanaitė, Lina, TRAINAVIČIUS, KĘSTUTIS, TUTKUVIENĖ, JANINA, STRUPAS, KĘSTUTIS, TAMOŠIŪNAS, ALGIRDAS EDVARDAS, BARAUSKAS, VIDMANTAS, CICĖNAS, SAULIUS, SLADKEVIČIUS, POVILAS, VERKAUSKAS, GILVYDAS, and Vilnius University
Subjects: Kiaušidės užsisukimas, Surgical treatment, ovarian torsion, children, surgical treatment, Chirurginis gydymas, Medicine, Ovarian torsion, Vaikų, Children
Abstract: Kiaušidžių užsisukimas – reta ūminė vaikų pilvo organų liga, kurios diagnostika sudėtinga, o dėl gydymo mokslininkai vis dar nesutaria. Tai pirmasis Lietuvoje mokslinis tyrimas, analizuojantis vaikų kiaušidžių užsisukimo priežastis, optimalius diagnostikos kriterijus, chirurginio gydymo taktiką ir metodus bei atokiuosius rezultatus. Šis atokiųjų konservatyvaus chirurginio gydymo rezultatų tyrimas yra didžiausias pasaulyje. Darbe nustatyta, kad 54,7 % kiaušidės užsisukimo priežasčių buvo įgimtos anatominės; 45,3 % ligonių kiaušidė užsisuko dėl patologinių darinių. Ligonėms iki menarchės statistiškai patikimai dažniau rasta brandžių teratomų (p=0,03). Specifinių vaikų kiaušidės užsisukimo simptomų ir požymių nenustatyta. Iki operacijos, tiriant echoskopu, užsisukusi kiaušidė buvo didesnė nei sveikoji vidutiniškai 21,48 (17,06) karto. Leukocitozė ir kiaušidės kraujotakos sutrikimai statistiškai patikimai dažnesni mergaitėms, kurioms kiaušidė pašalinta. Nė vienai mergaitei, kuriai kiaušidė buvo atsukta ir palikta pilvo ertmėje, nebuvo trombembolijos ir peritonito, nė vienai nerasta piktybinio naviko. Remiantis patologijos histologijos tyrimais, nustatyta, kad 14-oje (82,35 %) pašalintų kiaušidžių nekrozės ir patologinių darinių nebuvo, todėl jos galėjo būti išsaugotos. Patikrintų 95,24 % mergaičių ir moterų atsuktos kiaušidės anatomija ir folikulogenezė išliko normali. Ovarian torsion is a rare children’s acute abdominal disease which is difficult to diagnose and there is no consensus among scientists how to treat it. This is the first scientific research in Lithuania which analyses causes, optimal diagnostic criteria, the strategy, methods of surgical treatment and follow-up results of ovarian torsion in children. This is the largest research of the follow-up results of the conservative surgical treatment in the world. It was identified during the research that as many as 54.7% of the causes of ovarian torsion were congenital anatomical. In the case of 45.3% of the patients ovarian torsion was caused by pathological derivatives. In patients before menarche there were statistically significantly more mature teratomas (p=0.03). No specific symptoms of ovarian torsion in children were identified. Prior to the surgery, ultrasonography showed that the twisted ovary was on average 21.48 (17.06) times larger than the healthy ovary. Leukocytosis and ovarian blood flow disorders were statistically significantly more common in the case of ovarectomy. None of the girls who underwent detorsion with the ovary left in the abdominal cavity had thromboembolism or peritonitis; no malignant tumour was detected in any girl. According to the histopathological findings, no necrosis was detected in 14 (82.35%) removed ovaries, therefore they could be salvaged. Normal ovarian anatomy and folliculogenesis were retained in 95.24% of girls and women who were... [to full text]
Published: 2012

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