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In this review article, we discuss the latest advances and future perspectives of microfluidics for micro/nanoscale catalyst particle synthesis and analysis. In the first section, we present an overview of the different methods to synthesize catalysts making use of microfluidics and in the second section, we critically review catalyst particle characterization using microfluidics. The strengths and challenges of these approaches are highlighted with various showcases selected from the recent literature. In the third section, we give our opinion on the future perspectives of the combination of catalytic nanostructures and microfluidics. We anticipate that in the synthesis and analysis of individual catalyst particles, generation of higher throughput and better understanding of transport inside individual porous catalyst particles are some of the most important benefits of microfluidics for catalyst research.

Sepsis is a syndromic entity with high prevalence and mortality. The management of sepsis is standardized and exhibits time-dependent efficiency. However, the management of patients with sepsis is complex. The heterogeneity of the forms of presentation can make it difficult to detect and manage such cases, in the same way as differences in training, professional competences or the availability of health resources. The Advisory Commission for Patient Care with Sepsis (CAAPAS), comprising 7 scientific societies, the Emergency Medical System (SEM) and the Catalan Health Service (CatSalut), have developed the Interhospital Sepsis Code (CSI) in Catalonia (Spain). The general objective of the CSI is to increase awareness, promote early detection and facilitate initial care and interhospital coordination to attend septic patients in a homogeneous manner throughout Catalonia.

INTRODUCCION. El alojamiento específicamente rural. En 1988, Venancio Bote hablaba de cuatro tipos de alojamiento específicamente rurales: hoteles rurales de calidad, casas de alquiler rehabilitadas, alquiler de habitaciones y camping rurales (Bote Gómez 1988). Desde entonces, una década más tarde, la situación ha variado sustancialmente, se han desarrollado los alojamientos rurales de un modo, vertiginosos, proliferando los tipos, subtipos, variedades, etc., de una forma que podríamos calificar como exagerada. Cada comunidad autónoma ha intentado crear un tipo de alojamiento diferenciado del resto, que sirviese como insignia del turismo rural de la región, como símbolo de diferenciación (tanto Blanco 1996, como la Secretaría General de Turismo 1996, ofrecen un listado detallado de todas las denominaciones y tipos de vivienda reglamentadas por las comunidades autónomas). En cierto modo ...

XII Congreso Nacional de Agricultura, Madrid 24-26 de noviembre de 2009, Marketing of cultured and harvested shellfish is linked to monitoring programs for granting food safety. Its complexity requires constant cooperation between research and monitoring laboratories in order to improve sampling and analysing performances, achieve legal requirements, etc. for increasing consumer’s health protection but not reducing producer’s benefits. The JACUMAR project «Comparison of methodologies for the evaluation of Paralytic Shellfish Poisoning (PSP) toxins in bivalves. Application for aquaculture in Spain» groups research and monitoring laboratories from Galicia, Andalucía and Cataluña. Efforts are focused on detection and quantification of PSP toxins, searching an analytical method able to fulfil technical and management requirements, Este proyecto está financiado por la Junta Asesora de Cultivos Marinos (JACUMAR), y los programas de control por los gobiernos autónomos de Galicia, Andalucía y Cataluña

Tras realizar una búsqueda bibliográfica en nuestro país y constatar la ausencia de comunicaciones o artículos originales acerca del tratamiento con baclofeno intratecal para las formas generalizadas de tétanos, nuestro objetivo es dar a conocer dicho tratamiento, a través de la experiencia de un único caso clínico, con buen resultado. En relación con el caso, revisamos la farmacocinética y farmacodinamia del baclofeno y su posible utilidad en el tratamiento del tétanos. After making a bibliographic search in our country and demonstrating the lack of original articles or communications on treatment with intrathecal baclofen for the generalized forms of tetanus, our objective is to present this treatment based on the successful experience of one clinical case. In relationship to the case, we review baclofen pharmacokinetic and pharmacodynamic effects and its possible utility in the treatment of tetanus.

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Self-assembled cationic micelles are an attractive platform for binding biologically-relevant polyanions such as heparin. This has potential applications in coagulation control, where a synthetic heparin rescue agent could be a useful replacement for protamine, which is in current clinical use. However, micelles can have low stability in human serum and unacceptable toxicity profiles. This paper reports the optimi- sation of self-assembled multivalent (SAMul) arrays of amphiphilic ligands to bind heparin in competitive conditions. Specifically, modification of the hydrophobic unit kinetically stabilises the self-assembled nanostructures, preventing loss of binding ability in the presence of human serum – cholesterol hydro- phobic units significantly outperform systems with a simple aliphatic chain. It is demonstrated that serum albumin disrupts the binding thermodynamics of the latter system. Molecular simulation shows aliphatic lipids can more easily be removed from the self-assembled nanostructures than the cholesterol ana- logues. This agrees with the experimental observation that the cholesterol-based systems undergo slower disassembly and subsequent degradation via ester hydrolysis. Furthermore, by stabilising the SAMul nano- structures, toxicity towards human cells is decreased and biocompatibility enhanced, with markedly improved survival of human hepatoblastoma cells in an MTT assay.