1. Relationship between White Matter Lesions and Self-reported Chewing Difficulty in Japanese Adults: A Cross-sectional Study
- Author
-
IWAI, KOMEI, AZUMA, TETSUJI, YONENAGA, TAKATOSHI, SASAI, YASUYUKI, HATTORI, KEITA, YOKOYA, RYUJI, WATANABE, KAZUTOSHI, OBORA, AKIHIRO, DEGUCHI, FUMIKO, KOJIMA, TAKAO, FUJIWARA, SHUU, and TOMOFUJI, TAKAAKI
- Subjects
white matter lesions ,cross-sectional studies ,brain dock checkups ,chewing status - Abstract
This cross-sectional study investigated the relationship between white matter lesion (s WMLs) and selfreported chewing status among Japanese adults. The participants were 570 individuals (369 males, 201 females; mean age, 54.0 years) who underwent brain dock checkups at Asahi University Hospital Human Health Center between April 2019 and March 2020. The presence of WMLs was confirmed by brain magnetic resonance imaging (MRI) in brain dock checkups. Chewing status was evaluated using a self-reported questionnaire. WMLs were found in 272 participant (s 48%). Presence of WMLs was positively related with age (older; odds ratio [OR], 1.130; 95% confidence interva [l CI], 1.100 to 1.161), body mass index (BMI) (higher; OR, 1.103; 95%CI, 1.038 to 1.171), and chewing status (difficulty; OR, 2.794; 95%CI, 1.617 to 4.827) after adjusting for gender, HbA1c, hypertension, heart disease, and medication history. Furthermore, the proportion of participants with chewing difficulty increased according to WML grade (p < 0.001). In conclusion, presence of WMLs in Japanese adults showed a relationship with self-reported chewing difficulty.
- Published
- 2023