368 results on '"Sara Fernandes"'
Search Results
2. Relation of COVID-19 with liver diseases and their impact on healthcare systems: The Portuguese case
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Sara Fernandes, Milaydis Sosa-Napolskij, Graça Lobo, and Isabel Silva
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Gastroenterology ,General Medicine - Published
- 2023
3. Diagnostic Accuracy of Fine-Needle Biopsy in the Detection of Thyroid Malignancy: A Systematic Review and Meta-analysis
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Vivian Hsiao, Elian Massoud, Catherine Jensen, Yanchen Zhang, Bret M. Hanlon, Mary Hitchcock, Natalia Arroyo, Alexander S. Chiu, Sara Fernandes-Taylor, Oguzhan Alagoz, Kaitlin Sundling, Virginia LiVolsi, and David O. Francis
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Surgery - Abstract
ImportanceFine-needle biopsy (FNB) became a critical part of thyroid nodule evaluation in the 1970s. It is not clear how diagnostic accuracy of FNB has changed over time.ObjectiveTo conduct a systematic review and meta-analysis estimating the accuracy of thyroid FNB for diagnosis of malignancy in adults with a newly diagnosed thyroid nodule and to characterize changes in accuracy over time.Data SourcesPubMed, SCOPUS, and Cochrane Central Register of Controlled Trials were searched from 1975 to 2020 using search terms related to FNB accuracy in the thyroid.Study SelectionEnglish-language reports of cohort studies or randomized trials of adult patients undergoing thyroid FNB with sample size of 20 or greater and using a reference standard of surgical histopathology or clinical follow-up were included. Articles that examined only patients with known thyroid disease or focused on accuracy of novel adjuncts, such as molecular tests, were excluded. Two investigators screened each article and resolved conflicts by consensus. A total of 36 of 1023 studies met selection criteria.Data Extraction and SynthesisThe MOOSE guidelines were used for data abstraction and assessing data quality and validity. Two investigators abstracted data using a standard form. Studies were grouped into epochs by median data collection year (1975 to 1990, 1990 to 2000, 2000 to 2010, and 2010 to 2020). Data were pooled using a bivariate mixed-effects model.Main Outcomes and MeasuresThe primary outcome was accuracy of FNB for diagnosis of malignancy. Accuracy was hypothesized to increase in later time periods, a hypothesis formulated prior to data collection.ResultsOf 16 597 included patients, 12 974 (79.2%) were female, and the mean (SD) age was 47.3 (12.9) years. The sensitivity of FNB was 85.6% (95% CI, 79.9-89.5), the specificity was 71.4% (95% CI, 61.1-79.8), the positive likelihood ratio was 3.0 (95% CI, 2.3-4.1), and the negative likelihood ratio was 0.2 (95% CI, 0.2-0.3). The area under the receiver operating characteristic curve was 86.1%. Epoch was not significantly associated with accuracy. None of the available covariates could explain observed heterogeneity.Conclusions and RelevanceAccuracy of thyroid FNB has not significantly changed over time. Important developments in technique, preparation, and interpretation may have occurred too heterogeneously to capture a consistent uptrend over time. FNB remains a reliable test for thyroid cancer diagnosis.
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- 2023
4. Effects of hospital facilities on patient outcomes after cancer surgery
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Knight, Sr, Chu, K, Lapitan, Mc, Dare, Aj, Pius, R, Shaw, Ca, Drake, Tm, Norman, L, Ademuyiwa, Ao, Adisa, Ao, Aguilera, Ml, Al-Saqqa, Sw, Al-Slaibi, I, Bhangu, A, Biccard, Bm, Brocklehurst, P, Costas-Chavarri, A, Elhadi, M, Fairfield, Cj, Fitzgerald, Je, Ghosh, D, Glasbey, J, Henegouwen, Miv, Ingabire, Jca, Kingham, Tp, Lawani, I, Lieske, B, Lilford, R, Martin, J, Mclean, Ka, Moore, R, Morton, D, Nepogodiev, D, Ntirenganya, F, Pata, F, Pinkney, T, Stephen, R Knight, Catherine, A Shaw, Riinu, Pius, Thomas, M Drake, Lisa, Norman, Adesoji, O Ademuyiwa, Adewale, O Adisa, Maria Lorena Aguilera, Sara, W Al-Saqqa, Ibrahim, Al-Slaibi, Aneel, Bhangu, Bruce, M Biccard, Peter, Brocklehurst, Ainhoa, Costas-Chavarri, Kathryn, Chu, Anna, Dare, Muhammed, Elhadi, Cameron, J Fairfield, J Edward Fitzgerald, Dhruv, Ghosh, James, Glasbey, Mark, I van Berge Henegouwen, C Allen Ingabire, J, T Peter Kingham, Marie Carmela Lapitan, Ismaïl, Lawani, Bettina, Lieske, Richard, Lilford, Janet, Martin, Kenneth, A McLean, Rachel, Moore, Dion, Morton, Dmitri, Nepogodiev, Faustin, Ntirenganya, Francesco, Pata, Thomas, Pinkney, Ahmad Uzair Qureshi, Antonio Ramos-De la Medina, Aya, Riad, Hosni Khairy Salem, Joana, Simões, Richard, Spence, Neil, Smart, Stephen, Tabiri, Hannah, Thomas, Thomas, G Weiser, Malcolm, West, John, Whitaker, Ewen, M Harrison, Arben, Gjata, Maria Marta Modolo, Sebastian, King, Erick, Chan, Sayeda Nazmun Nahar, Ade, Waterman, Dominique, Vervoort, Alemayehu Ginbo Bedada, Bernardo De Azevedo, Ana Gabriela Figueiredo, Manol, Sokolov, Venerand, Barendegere, Gerald, Ekwen, Arnav, Agarwal, Qinyang, Liu, Juan Camilo Correa, Kalisya Luc Malemo, Jacques, Bake, Jakov, Mihanovic, Kamila, Kunčarová, Julius, Orhalmi, Hosni, Salem, Jyri, Teras, Aristotelis, Kechagias, Alexis, P Arnaud, Judith, Lindert, Vasileios, Kalles, Maria-Lorena, Aguilera-Arevalo, Gustavo, Recinos, Zsolt, Baranyai, Basant, Kumar, Harish Neelamraju Lakshmi, Sanoop Koshy Zachariah, Philip, Alexander, Sunil Kumar Venkatappa, Pramesh, C, Radhian, Amandito, Christina, Fleming, Luca, Ansaloni, Gianluca, Pellino, Ahmed, M Altibi, Ibrahim, Nour, Intisar, Hamdun, Ali, M Ghellai, Donatas, Venskutonis, Tomas, Poskus, Justas, Zilinskas, Precious, Malemia, Yong Yong Tew, Elaine, Borg, Sarah, Ellul, Fatima Zahraa Wafqui, David, W Borowski, Anne Sophie van Dalen, Cameron, Wells, Harissou, Adamou, Adesoji, Ademuyiwa, Adewale, Adisa, Kjetil, Søreide, Sara Al Saqqa, Osaid, Alser, Haya, Tahboub, Helmut Alfredo Segovia Lohse, Sebastian Shu Yip, Piotr, Major, António Sampaio Soares, Matei Razvan Bratu, Andrey, Litvin, Armen, Vardanyan, Ahmad, Gudal, Naif, Albati, Jovan, Juloski, Miran, Rems, Sarah, Rayne, Stephanie Van Straten, Yoshan, Moodley, Irene Ortega Vázquez, Jaime, Ruiz-Tovar, Kithsiri Janakantha Senanayake, Sujeewa Priyantha Bandara Thalgaspitiya, Omer Abdelbagi Omer, Anmar, Homeida, Yucel, Cengiz, Daniel, Clerc, Muhammad, Alshaar, Hanen, Bouaziz, Yuksel, Altinel, Matthew, Doe, Maryna, Freigofer, Ella, Teasdale, Rakan, Kabariti, Joshua Michael Clements, Stephen Richard Knight, Ahsan, Ashfaq, Ijeoma, Azodo, Gabriela, Wagner, Ivan, Trostchansky, Mayaba, Maimbo, David, Linyama, Helidon, Nina, Amanda, Zeko, Claudio Gabriel Fermani, Santiago, Villalobos, Federico, Carballo, Pablo, Farina, Sebastian, Guckenheimer, Marilla, Dickfos, Ankit, Ajmera, Chester, Chong, Ralph, Gourlay, Sikandar, Hussaini, Yi Jia Lee, Adeeb, Majid, Peter, Martin, Rebecca, Miles, Owen James Morris, Jamie, Phua, William, Ridley, Tarunpreet, Saluja, Ryan Renxin Tan, Jen, Teh, Anna, Wells, Bharti, Arora, Qaasim, Dollie, Debbie, Ho, Yanru, Ma, Omattage Mahasha Perera, Anthony, Truong, Amanda Caroline Dawson, Bryan, Lim, Upuli, Pahalawatta, Jacqueline, Phan, Xiao-Ming Sarah Woon-Shoo-Tong, Andrea, Yeoh, Lillian, Charman, Andrew, Drane, Sharon, Laura, Charmaine Chu Wen Lo, Amy, Mozes, Rita, Poon, Hao Han Tan, Ellen, Wall, Prakshi, Chopra, Jasmine De Giovanni, Bal, Dhital, Brian, Draganic, Alexander, Duller, Jonathan, Gani, Yao Kuan Goh, Jun Young Jeong, Brendan, Mcmanus, Prakash, Nagappan, Peter, Pockney, Anya, Rugendyke, Mahsa, Sarrami, Stephen, Smith, Vanessa, Wills, Hsu Ven Wong, Geoffrey, Ye, Geoffrey, Zhang, Ethan, Brooker, Daniel, Feng, Bonnie, Lau, Carlin, Ngai, Sarah, Birks, David, Gyorki, Jaime Otero de Pablos, Ali, Abbosh, Chris, Gillespie, Ahmed, Mahmoud, Bianca, Kwan, Joshua, Lawson, Andrea, Warwick, Janne, Bingham, Andrew, J Cockbain, Nagendra Naidu Dudi-Venkata, Jordan, Ellaby-Hall, Ben, Finlay, Emily, Humphries, Jade, Pisaniello, Monique, Pisaniello, Salma, Salih, Tarik, Sammour, Haidar Hadri Abd Wahab, April De Silva, Nicola, Hayward, Kartik, Iyer, Guy, Maddern, Gian Andrea Prevost, Naga, Annapureddy, Krishna Pranathi Settipalli, Jeremy, Yeo, Lucy, Hempenstall, Lily, Pham, Shaun, Purcell, Cherry, Talavera, Ashish, I Vaska, Gurpreet, Chaggar, Phillip, Chrapko, Annelise, Cocco, Sarah Michelle Crystal Jade Coulter-Nile, Grahame, Ctercteko, James, French, Houchen, Gong, Martijn, Gosselink, Thuvarahan, Jegathees, Ivan, Jin, Michelle, Kalachov, Kathryn, Kiefhaber, Katherine, Lee, Jason, Luong, Steven, Phan, Henry, Pleass, Kelly, Veale, Zhi, Zeng, Angela, Au, Ashe, Debiasio, Idy, Deng, Jananee, Myooran, Amrita, Nair, Peter, Stewart, Anton, Stift, Lukas Walter Unger, Kerstin, Wimmer, Nabila, Ahmed, Syed, Hasan, Saber, Rahman, Margaret, O'Shea, Greg, Padmore, Adrian, Peters, Pietro, Perduca, Guenda, Pulcina, Nicolas, Tinton, Frederic, Buxant, Elsa, Dabin, Giulia, Garofalo, Francis, Dossou, Freddy Houehanou Rodrigue Gnangnon, Yacoubou Imorou Souaibou, Pako, Motlaleselelo, Omphile, Tlhomelang, Igor Lima Buarque, Gustavo Mendonça Ataíde Gomes, Aldo Vieira Barros, Ilia, Batashki, Nikolai, Damianov, Vladislav, Stoyanov, Dragomir, Dardanov, Svilen, Maslyankov, Plamen, Petkov, George, Todorov, Evgeni, Zhivkov, Aygulya, Akisheva, Miguel Angel Castilla Moreno, Geno, Genov, Ivelina, Ilieva, Tsvetomir, Ivanov, Martin, Karamanliev, Azhar, Khan, Emil, Mitkov, Tsanko, Yotsov, Boyko, Atanasov, Nikolay, Belev, Mihail, Slavchev, Carlos, Nsengiyumva, Elgan, Jones, Simon, Stock, Steve, Kyota, James, Brown, Tresor Mabanza, K, Lemery Nigo Samuel, Chidi, Otuneme, Ngwang, Prosper, Franklin, Umenze, Marylise, Boutros, Natasha, Caminsky, Sinziana, Dumitra, Richard, Garfinkle, Dominique, Morency, Ebram, Salama, Alexander, Banks, Lorenzo, Ferri, Haitian, He, Amit, Katz, Alexander Sender Liberman, Sarkis, Meterissian, Allison, Pang, Elena, Parvez, Usmaan, Hameed, Fahima, Osman, Sangita, Sequeira, Natalie, Coburn, Alisha, Jaffer, Paul, Karanicolas, Matthew, Mosseler, Reilly, Musselman, Xinyuan, Liu, Ching Wan Yip, Juan Sebastian Garces-Otero, Carolina, Guzman, Sebastian, Sierra, Andres Uribe Valencia, Paulo Andrés Cabrera Rivera, Saul, Camelo, Andrea, Gonzalez, Alejandro, González-Orozco, Manuel Santiago Mosquera Paz, Carlos J- Perez Rivera, Felipe, Gonzalez, Andres, Isaza-Restrepo, Laura, Nino-Torres, Natalia Arias Madrid, Maria Clara Mendoza Arango, Justin, Tsandiraki, Damir, Jemendžić, Branislav, Kocman, Oliver, Šuman, Renata, Canic, Darko, Jurišić, Ivana, Karakas, Ana Krizanovic Rupcic, Vlatka, Pitlovic, Josip, Samardžić, Mario, Kopljar, Ivan, Bacic, Edgar, Domini, Robert, Karlo, Danijela, Miljanić, Andrea, Simic, Mariam, Ahmed, Majdi Al Nassrallah, Rabiya, Altaf, Talal, Amjad, Ruba, Eltoum, Heba, Haidar, Alhassan, Hassan, Omar, Khalil, Marwan, Qasem, Rommel, Ramesh, Gautham, Sajith, Maham, Wisal, Jan, Žatecký, Michele, Bujda, Katerina, Jirankova, Ales, Paclik, Aya, Abdallah, Mariam Abdulgawad Almogy, Esraa Ayman El-Sawy, Ahmed Moustafa ElFayoumy, Nourhan, Elghareeb, Nourhan Ahmed Esmat, Ahmed, Fadel, Abdullah, Habater, Heba, Hamdy, Amr, Hefni, Marwa, Kamal, Norhan Mohamed Abobakr, Ahmed, Sayed, Nancy, Shaker, Ehab, Taha, Hoda, Tharwat, Omar, Zakaria, Ibrahem, Abdelmotaleb, Ali, Al-Dhufri, Hamza, S Al-Himyari, Enas El Sheikh, Asmaa, Eldmaty, Aya, Elkhalawy, Ahmed, M Elkhashen, Kithara, Magdy, Safa, Mostafa, Habib Doutoum Sadia, Mohamed Mahmoud Saleh, Dina, Samir, Mohamed Yahia Mohamed Ali, Mahmoud, A Nassar, Samar, Abdelhady, Aly, Abdelrazek, Israa, Abdelsalam, Aya, El-Sawy, Eman, Essam, Mohamed, Gadelkarim, Khaled, Ghaly, Mohamed, Hassabalnaby, Rana, Masarani, Nourhan Mohamed Shaaban, Ahmed, Sabry, Menatalla, Salem, Nourhan Akram Soliman, Diaaaldin, Zahran, Moustafa Ramadan Abou El Soud, Esraa Tarek Badr, Hala, Borham, Nehal, Elmeslemany, Mohammad, Elsayed, Fawzia, Elsherif, Sara, Eslam, Gehad, Gaber, Sondos, Ibrahim, Yara, Kamh, Abdelrahman, Mahmoud, Shimaa Gamal Mohamed, Eman, Morshedy, Cinderella, Omar, Fatima Salem Soliman, Shaza, Abdelkawy, Naglaa, Abdelmohsen, Mahmoud, Abdelshakour, Ahmed, Dahy, Norhan, Gamal, Mohammed, Gamal, Ahmad, Hasan, Helal, Hetta, Nehad, Mousa, Mohamed, Omar, Somia, Rabie, Mahmoud, Saad, Bakeer, Saleh, Marwa Sayed Mohamed, Muhammad, Shawqi, Heba Abdelhady Mousa, Mostafa, Alnoury, Mohamed, Elbealawy, Ahmed, Elshafey, Muhammad Essam Ibrahim El Desouki Muhammad Ahmed, Mennatullah, Ghonaim, Fawzy, Hgag, Mohamed, Ibrahim, Mahmoud, Morsy, Mohamed Reda Loaloa, Ahmed, Refaat, Hadeer, Samir, Fatma, Shahien, Mohamed, Sobhy, Fathy, Sroor, Esraa, Abdellatif, Marina, Adel, Amr Abdelghani Afifi, Eman, Afifi, Marco, Antaky, Amr, Dawoud, Naira El Zoghby, Amira, El-Remaily, Ali Abdelazez Elzanfaly, Ahmed, Gadallah, Fatma Alzahraa Gamal, Omar, Hashem, Shrouk Medhat Youssef, Aliaa Muhammad Attyah, Malak, Munir, Omar, Shazly, Esraa, Taha, Karim, Wilson, Sawsan, Adel, Asmaa, Ali, Esraa, Eid, Esraa, Elhelow, Marwa, Elmahdy, Bassant, Elshatby, Amany Hossam El-Din Zakaria, Ahmad, Hossny, Eman, Ibrahim, Ahmed, M Yonis, Maram, Metwalli, Basant, Yousry, Esraa, Zid, Mina, A Yacoub, Ahmed, Abdelhakim, Nervana, Abouelsoad, Mo'Min, Alkhatib, Ahmed, Ashraf, Alaa, Ashraf, Yasmin, Elazab, Mahmoud, Elfanty, Osama, Elkabir, Mai, Elsayed, Ahmed, Elshimy, Hager, Elsobky, John, Eskander, Ahmed, Gad, Ward, Hamsho, Noura Khaled Abdelwahed, Menna, Magdy, Dalia, Moharam, Abeer, Osama, Shereen, Ramadan, Radwa, Roum, Taqwa, Sayed, Tarneem, Shehada, Ahmed Mohy Zidan, Khalid, Abbas, Amr, Ali, Mohamed, Attia, Mohamed, Balata, Ayman El Nakeeb, Mohamed Ibrahim Elsayed Elewaily, Ahmed, Elfallal, Hossam, Elfeki, Ahmed, Elkhadragy, Sameh, Emile, Helmy, Ezzat, Hasnaa, Hosni, Islam, Mansour, Waleed, Omar, Gehad, Othman, Kareem, Sadek, Mostafa, Shalaby, Noura, Shehab-Eldeen, Rawda Anas Khalifa, Helmy, Badr, Mostafa, Eldeep, Ahmed, Eldeep, Amany Eldoseuky Mohammed, Salwa, Khallaf, Eman Magdy Hegazy, Rokia, Mahmoud, Pola, Mikhail, Mahmoud, Morsi, Sara, Mowafy, Dina, Raafat, Amina, Safy, Marwa, Sera, Ahmed Shible Sera, Mostafa Salim Mohamed AbdAllah, Muhammad, Abdelkader, Abdulrahman Osama Abdou, Ahmedgaber, Ahmed, Shireen, Gaafar, Fatma Ibrahim Negm, Mina, Lapic, Ahmed, Maher, Hagar, Mahmoud, Ahmed, Mostafa, Mohamed, Samir, Fatma, Samy, Nourhan, Semeda, Hind, I Shalaby, Alaa, El-Taweel, Ahmed Galal Elnagar, Ahmed Gamal Hemidan, Mohamed, Hussein, Ahmed, A Kandil, Moawad, Mf, Ayat Allah Nasser Hamamah, Mostafa, Soliman, Mohamed, Abdelkhalek, Noura Abdelmaksoud Tawakel, Ahmed Mohamed Abdelwahed, Alrawy, Abdou, Khalid, Atallah, Mohammed Yasser Elsherbeny, Eman, Emara, Mohamed, Hamdy, Omar, Hamdy, Amira, Haron, Salma, Ismail, Islam Hany Metwally, Nihal Mohamed Hamed Elgaml, Ahmed, Nassar, Basel, Refky, Mirna, Sadek, Mahmoud, Saleh, Asmaa, Yunes, Mai, Zakaria, Mohammed, Zuhdy, Notila, Fayed, Mohammed Mustafa Hassan Mohammed, Sander, Kütner, Priit, Melnik, Indrek, Seire, Toomas, Ümarik, Eppu, Ainoa, Verner, Eerola, Hanna, Koppatz, Laura, Koskenvuo, Ville, Sallinen, Sini, Takala, Jevgeni, Katunin, Arto, Turunen, Niki, Christou, Muriel, Mathonnet, Vincent, Lavoue, Krystel Nyangoh Timoh, Lucie, Soulabaille, Romain, Lesourd, Aude, Merdrignac, Laurent, Sulpice, Benoît, André, Elodie, Chantalat, Charlotte, Vaysse, Bertrand, Dousset, Sebastien, Gaujoux, Gregory, Martin, Octavian, Clonda, Domantas, Juodis, Klaus, Kienle, Andras, Mravik, Samuel, Palmer, Gabor, Szabadhegyi, Anita Eseenam Agbeko, Solomon, Gyabaah, Frank Enoch Gyamfi, Nuhu, Naabo, Atta Owusu Senior, Joseph, Yorke, Frank, Owusu, Francis, Abantanga, Theophilus Teddy Kojo Anyomih, Abdul-Jalilu Mohammed Muntaka, Emmanuel Owusu Abem, Mohammed, Sheriff, Paul, M Wondoh, Dimitrios, Balalis, Dimitrios, Korkolis, Georgios, Gkiokas, Eirini, Pantiora, Theodosios, Theodosopoulos, Argyrios, Ioannidis, Konstantinos, Konstantinidis, Sofia, Konstantinidou, Nikolaos, Machairas, Anna, Paspala, Anastasia, Prodromidou, Christos, Chouliaras, Konstantinos, Papadopoulos, Ioannis, Baloyiannis, Ioannis, Mamaloudis, George, Tzovaras, Ioanna, Akrida, Maria-Ioanna, Argentou, Stylianos, Germanos, Evangelos, Iliopoulos, Ioannis, Maroulis, George, Skroubis, George, Theofanis, Christos, Chatzakis, Orestis, Ioannidis, Lydia, Loutzidou, Panagiotis, Karathanasis, Nikolaos, Michalopoulos, Charalampos, Theodoropoulos, Dimitrios, Theodorou, Tania, Triantafyllou, Zoe, Garoufalia, Natasha, Hasemaki, Michalis, Kontos, Gregory, Kouraklis, Stylianos, Kykalos, Theodore, Liakakos, Eustratia, Mpaili, Alexandros, Papalampros, Dimitrios, Schizas, Athanasios, Syllaios, Ekaterini Christina Tampaki, Antonios, Tsimpoukelis, Maria Ioanna Antonopoulou, Eirini, Deskou, Dimitrios, K Manatakis, Dimitrios, Papageorgiou, Menelaos, Zoulamoglou, Christos, Anthoulakis, Michalis, Margaritis, Nikolaos, Nikoloudis, Veronica, Campo, André, Ceballos, Mario-Andrés, Flores, Waleska, Giron, Donghyun, Ko, Gabriel, Martinez, Verónica Rivera Lara, Nataly, Rueda, Andres, Sanchez, Jorge Carlos Guillermo Tejeda Garrido, Alvaro Eduardo Alvarez Rivera, Elvis Benjamin Bamaca Ixcajoc, Lilian Elizabeth Barreda Zelaya, Patricia, Chacòn-Herrera, Ligia Margarita Corea Ruiz, Guillermo, Echeverria-Davila, Mario, Garcia, Danilo, García, Edgar Fernando Gutiérrez Mayen, Noriega, José, Nery, Mazariegos, Diego, Méndez, Michael Paniagua Espinoza, David, Bardos, Marton, Benke, Kristof, Illes, Balint András Kokas, Réka, Szabó, Akhila, Appukuttan, Anjitha, Asok, D K, Vijaykumar, Kapil, Malik, Praveen, Ravishankaran, Ritesh, Tapkire, Guru, Moorthy, Joyner, Abraham, Ramesh, Muthuvel, John, Alapatt, Abhay, Kattepur, Nizamudheen, Pareekutty, Mebanshanbor, Garod, Caleb, Harris, Cliff, Wanniang, Ashish, Gupta, Deepak, Nehra, Sanjeev, Parshad, Rajgopal, Acharya, Rajendra, Badwe, Manish, Bhandare, Urvashi, Jain, Karishma, Kirti, Nita, Nair, Shailesh, Shrikhande, Purvi, Thakkar, Premkumar, Anandan, C S, Archana, Arun Holenarasipur Narasannaiah, Tejaswi, Jagarlamudi, M R, Rashmi, Mallikarjuna, Manangi, Abhishek, Raghavendra, K Seshagiri Rao, Vinay, S, Vinay, Sajjan, Aneesh, Shenoy, Santhosh Shivashankar Chikkanayakanahalli, Kavya, Tharanath, Sushmita, V, Peter, Adidharma, Raksheeth, Agarwal, Phebe Anggita Gultom, Ghafur Rasyid Arifin, Matthew, Billy, Zatira, Elfizri, Alessa, Fahira, Devi, Felicia, Triana Hardianti Gunardi, Nadya, Johanna, Nadia Rahmadiani Nugrahadi, Sonar Soni Panigoro, Siti, Rahmayanti, Retta Catherina Sihotang, Santi Yuanita Brata, Hadi, Winoto, Nastaran, Barati, Manoochehr, Karami, Hamidreza, Khorshidi, Homa, Naderifar, Mazin, A Abdulla, Maggie, Coleman, Ronan, J Doherty, Rob, Hannon, Brenda, Murphy, Aine, Stakelum, Des, Winter, Lylas, Aljohmani, Richard, Farnan, Yeshey, Seldon, Tanna, Tan, Shriya, Varghese, Mohammad, Alherz, Muaaz, Ather, Mohammad, Bajilan, Vivien, Graziadei, Isobel, Pilkington, Omar, Quidwai, Paul, Ridgway, Haaris, Shiwani, Abd Al-Rahman Tahir, Eimear, Blunnie, Daniel, Burke, Niall, Kennedy, Kate, Macdonagh, Maeve, O'Neill, Siobhan, Rooney, Giuseppe, Falco, Guglielmo, Ferrari, Simone, Mele, Gabriela Elisa Nita, Lara, Ugoletti, Maurizio, Zizzo, Gianmaria, Confalonieri, Giovanni, Pesenti, Fulvio, Tagliabue, Gianluca, Baronio, Deborah, Ongaro, Giacomo, Pata, Bruno, Compagnoni, Renato, Salvadori, Lucio, Taglietti, Nicola, D'Alessandro, Pierpaolo Di Lascio, Giovanni, Pascale, Luca, Bortolasi, Tommaso, Campagnaro, Massimo, Carlini, Giorgio, Lisi, Davide, Lombardi, Corrado, Pedrazzani, Domenico, Spoletini, Giulia, Turri, Paola, Violi, Donato Francesco Altomare, Fabrizio, Aquilino, Nicola, Musa, Vincenzo, Papagni, Arcangelo, Picciariello, Leonardo, Vincenti, Dario, Andreotti, Savino, Occhionorelli, Matteo, Tondo, Stefano Maria Massimiliano Basso, Paolo, Ubiali, Riccardo, Cirelli, Marco Enrico Mario Maino, Guglielmo Niccolò Piozzi, Emanuele, Picone, Rosa, Scaramuzzo, Giovanni, Sinibaldi, Alfonso, Amendola, Lorenzo, Anastasio, Luigi, Bucci, Emanuele, Caruso, Antonio, Castaldi, Sara Di Maso, Vincenza Paola Dinuzzi, Giovanni, Esposito, Maria, Gaudiello, Mariano Cesare Giglio, Paola Antonella Greco, Gaetano, Luglio, Andrea, Manfreda, Ester, Marra, Federica, Mastella, Gianluca, Pagano, Roberto, Peltrini, Vincenzo, Pepe, Michele, Sacco, Viviana, Sollazzo, Giovanni, Spiezio, Ettore, Cianchetti, Nunzia, Menduni, Michele Maria Carvello, Francesca Di Candido, Antonino, Spinelli, Fabio, Corsi, Luca, Sorrentino, Fabio, Marino, Emanuele Luigi Giuseppe Asti, Luigi, Bonavina, Emanuele, Rausa, Martina, Asta, Andrea, Belli, Francesco, Bianco, Carmela, Cervone, Paolo, Delrio, Armando, Falato, Andrea Fares Bucci, Rita, Guarino, Ugo, Pace, Daniela, Rega, Emilia De Luca, Gaetano, Gallo, Giuseppe, Sammarco, Giuseppe, Sena, Giuseppina, Vescio, Letizia, Santandrea, Giampaolo, Ugolini, Davide, Zattoni, Nicola, Chetta, Gaetano, Logrieco, Serafino, Vanella, Gianluca, Garulli, Nicola, Zanini, Andrea, Bondurri, Francesco, Cammarata, Francesco, Colombo, Diego, Foschi, Giulia Maria Beatrice Lamperti, Anna, Maffioli, Gianluca Matteo Sampietro, Al'Ona, Yakushkina, Gloria, Zaffaroni, Enrico, Cicuttin, Maria Grazia Sibilla, Harmony, Impellizzeri, Marco, Inama, Gianluigi, Moretto, Sylvie, Mochet, Elisa, Ponte, Antonella, Usai, Stefano, Mancini, Andrea, Sagnotta, Luigi, Solinas, Elisa, Bolzonaro, Nicolò, Tamini, Gianluca, Curletti, Raffaele, Galleano, Michele, Malerba, Sofia, Campanella, Gianfranco, Cocorullo, Francesco, Colli, Paolino De Marco, Nicolò, Falco, Tommaso, Fontana, Leonel Jospin Kamdem Mambou, Antonella La Brocca, Leo, Licari, Brenda, Randisi, Giovanna, Rizzo, Giulia, Rotolo, Giuseppe, Salamone, Roberta, Tutino, Paolina, Venturelli, Stefano, Malabarba, Alessandro, Sgrò, Ivan, Vella, Bruno, Cirillo, Daniele, Crocetti, Giorgio De Toma, Pierfrancesco, Lapolla, Andrea, Mingoli, Paolo, Sapienza, Angela, Belvedere, Stefania, Bianchini, Margherita, Binetti, Arianna, Birindelli, Valeria, Tonini, Mauro, Podda, Fabio, Pulighe, Michele De Rosa, Lorenzo, Bono, Felice, Borghi, Paolo, Geretto, Maria Carmela Giuffrida, Corrado, Lauro, Alessandra, Marano, Luca, Pellegrino, Paola, Salusso, Diego, Sasia, Michela, Campanelli, Alberto Realis Luc, Mario, Trompetto, Roberto, Cardia, Nicola, Cillara, Antonio Nicola Giordano, Antonio, Costanzo, Mario Alessandro Giovilli, Luca, Turati, Silvestro, Canonico, Sciaudone, Guido, Francesco, Selvaggi, Lucio, Selvaggi, Nader, Albsoul, Ahmad, Albsoul, Ala'a Aldeen Alkhatib, Osama, Alsallaq, Justin, Z Amarin, Rami, Ayoub, Isam, Bsisu, S El Muhtaseb, M, Mohammad, Jabaiti, Jamal, Melhem, Yasmeen, Z Qwaider, Mohammad Hasan Salameh, Ahmad, Suleihat, Haya, H Suradi, Mohammad, Alammarin, Almoutuz, Aljaafreh, Mohammad Bani Hani, Zeina Bani Hani, Farah Bani Hani, Toqa, Fahmawee, Shadi, Hamouri, Cyrine, Katanani, Ra'Fat, Tawalbeh, Tamara, Tawalbeh, Hassan, Zawahrah, Mohamad, K Abou Chaar, Lana, Abusalem, Mahmoud, Al-Masri, Hani, Al-Najjar, Lutfi, Barghuthi, Zahra, Ahmed, Adnan, Maulana, Omar, Ngotho, Charbel, Kamau, Aruyaru Stanley Mwenda, Fridah, Bosire, Elizabeth, Mwachiro, Robert, Parker, Ian, Simel, Kimutai, Sylvester, Abdulmunem Ahmed Mustafa Althini, Sofian, Elbarouni, Aya Elseed Elbeshina, Ahmed, Gwea, Ans, Malek, Wedad Albashir Masoud Farag, Abdulwahab, Abdalei, Abu Baker Abdel Malik, Areej, Abo-Khammash, Ma'Aly, Abuhlaiga, Nour, Adnan, Marwa, Albaggar, Asma, Alfitory, Asma, Aljanfi, Fakhruddin, Almuzghi, Zohoor, Altumei, Fatima, Alzabti, Hana, Ashoushan, Mohamed, Assalhi, Joma, Azzubia, Sondos, Bnhameida, Malik, Delhen, Houssein, Elshafei, 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Olajide Abiola, Akinlabi Ajao, Anthony Ajiboye, Amarachukwu Etonyeaku, Julius Olaogun, Ademola Adebanjo, Opeoluwa Adesanya, Michael Olatunji Afolayan, Olanrewaju Balogun, Ayomide Makanjuola, Samuel Nwokocha, Rufus Wale Ojewola, Thomas Olagboyega Olajide, Adewale Aderounmu, Abdul-Rashid Adesunkanmi, Adewale Adisa, Augustine Agbakwuru, Adeleke Akeem Aderogba, Olusegun Isaac Alatise, Olukayode Arowolo, Oladejo Lawal, Tajudeen Mohammed, Chinedu Ndegbu, Olalekan Olasehinde, Funmilola Wuraola, Akinbolaji Akinkuolie, Amarachukwu Etonyeaku, Arinzechukwu Mosanya, Omobolaji Ayandipo, Peter Elemile, Taiwo Akeem Lawal, Samuel Ali Sani, Stephen Garba, Rebecca Hauwa Sani, Samson Olori, Henry Onyebuashi, Ifeanyi Umoke, Adedire Adenuga, Ademola Adeyeye, Olufemi Habeeb, Bashir Lawal, Abdulrasheed Nasir, Eirik Kjus Aahlin, Didrik Kjønås, Elisabeth Myrseth, Jibran Abbasy, Abdul Alvi, Omair Saleem, Asma Afzal, Anam Nazir, Muhammad Farooq, Ayesha Liaqat, Syed Asghar Naqi, Ali Raza, Muzna Sarfraz, Muhammad 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P., Nsengimana, V. J. P., Uwakunda, C., Abbas, M. M., Akeel, N., Aljiffry, M., Awaji, K., Farsi, A., Jamjoum, G., Khoja, A., Maghrabi, A., Malibary, N., Nassif, M., Saleem, A., Sultan, A., Tashkandi, W., Tashkandi, H., Trabulsi, N., Ba, M. B., Diallo, A. C., Ndong, A., Cuk, V., Jankovic, U., Koh, S. Z., Koh, F., Lee, K. C., Lee, K. Y., Lee, S., Leong, W. Q., Lui, S. A., Prakash, P., Grosek, J., Norcic, G., Tomazic, A., Fitchat, N., Jaich, R., Wineberg, D., Koto, M. Z., Baiocchi, D., Clarke, D., Steenkamp, C. J., Bannister, S., Boutall, A., Chinnery, G., Coccia, A., Dell, A., Karjiker, P., Kloppers, C., Loxton, N., Mabogoane, T., Malherbe, F., Panieri, E., Rayamajhi, S., van Wyngaard, T., Warden, C., Madiba, T. E., Pillay, N., Brooks, S., Kruger, C., Van Der Merwe, L. H., Gool, F., Kariem, M., Bougard, H., Kariem, N., Noor, F., Pillay, R., Steynfaardt, L., Gonzalez Gonzalez, L., Marin Santos, J. M., Martin-Borregon, P., Martinez Caballero, J., Nevado Garcia, C., Rodriguez Fraga, P., De Castro Parga, G., Fernandez Veiga, M. P., Garrido Lopez, L., Infante Pino, H., Lages Cal, I., Lopez Otero, M., Nogueira Sixto, M., Paniagua Garcia Senorans, M., Rodriguez Fernandez, L., Ruano Poblador, A., Rufo Crespo, E., Sanchez-Santos, R., Vigorita, V., Alonso Batanero, E., Asnel, D., Cifrian Canales, I., Contreras Saiz, E., De Santiago Alvarez, I., Diaz Vico, T., Fernandez Arias, S., Fernandez Martinez, D., Garcia Bernardo, C., Garcia Florez, L. J., Garcia Gutierrez, C., Garcia Munar, M., Marquez Zorrilla Molina, C. A., Merayo, M., Michi Campos, J. L., Moreno Gijon, M., Otero-Diez, J. L., Rodicio Miravalles, J. L., Solar-Garcia, L., Suarez Sanchez, A., Truan, N., Alejandre Villalobos, C., Caballero Diaz, Y., Jimenez, M., Montesdeoca, D., Navarro-Sanchez, A., Vega, V., Beltran de Heredia, J., Gomez, Z., Jezieniecki, C., Legido Moran, A. P., Montes-Manrique, M., Rodriguez-Lopez, M., Ruiz Soriano, M., Trujillo Diaz, J., Vazquez Fernandez, A., Argudo, N., Pera, M., Torrent Jansa, L., Garcia Dominguez, M., Goded, I., Roldon Golet, M., Talal El-Abur, I., Utrilla Fornals, A., Zambrana Campos, V., Aguilar Martinez, M. D. M., Bosch, M., Garcia-Catala, L., Sanchez-Guillen, L., Artigau, E., Gomez Romeu, N., Julia Bergkvist, D., Espina Perez, B., Morato, O., Olona, C., Dieguez, B., Forero-Torres, A., Losada, M., Gomez-Abril, S., Gonzalvez, P., Martinez, R., Navarro Martinez, S., Paya-Llorente, C., Perez Rubio, A., Santarrufina Martinez, S., Sebastian Tomas, J. C., Trullenque Juan, R., Gegundez Simon, A., Mate, P., Prieto-Nieto, M. I., Rubio-Perez, I., Urbieta, A., Vicario Bravo, M., Abello, D., Frasson, M., Garcia-Granero, A., Abad Gurumeta, A., Abad-Motos, A., Lucena-de Pablo, E., Nozal, B., Ripolles-Melchor, J., Salvachua, R., Ferrero, E., Garcia-Sancho Tellez, L., Picardo, A. L., Rojo Lopez, J. A., Zorrilla Matilla, L. P., Cagigas Fernandez, C., Castanedo Bezanilla, S., Estevez Tesouro, J., Fernandez-Diaz, M. J., Garcia Cardo, J., Gomez Ruiz, M., Gonzalez-Tolaretxipi, E., Jimeno Fraile, J., Poch, C., Rodriguez-Aguirre, M., Troche Pesqueira, N., Trugeda-Carrera, M. S., de la Torre, J., Blanco-Colino, R., Espin-Basany, E., Espinosa-Bravo, M., Morales Comas, C., Reyes Afonso, E., Rivero Deniz, J., Siso Raber, C., Verdaguer Tremolosa, M., Chandrasinghe, P., Kumarage, S., Wijekoon Arachchilage, N., Abdalla Ahmed Elkamel, A., A. Adam, M., Blomme, N., Thorell, A., Wogensen, F., Alga, A., Ansarei, D., Celebioglu, F., Heinius, G., Nigard, L., Pieniowski, E., Ahlqvist, S., Bjorklund, I., Franberg, A., Hakansson, M., Adamo, K., Franklin, O., Sund, M., Wiberg, R., Andersson, Y., Chabok, A., Nikberg, M., Kugelberg, A., Canonica, C., Christoforidis, D., Fasolini, F., Gaffuri, P., Giuliani, M., Meani, F., Popeskou, S. G., Pozza, S., Wandschneider, W., Peterer, L., Widmer, L. W., Zimmermann, B., Bakoleas, P., Chanousi, I., Charalampidou, L., Grochola, L. F., Heid, F., Ntaoulas, S., Outos, M., Peros, G., Podolska-Skoczek, H., Reinisch, K. B., Zielasek, C., Demartines, N., Gilgien, J., Kefleyesus, A., St-Amour, P., Toussaint, A., Alhimyar, M., Alsaid, B., Alyafi, A., Alkhaledi, A., Kouz, B., Omarain, A., Al-Sabbagh, Y., Alkhatib, H., Sara, S., Alhaj, A., Danial, A., Kadoura, L., Maa Albared, S., Monawar, Y., Nahas, L., Abd, B., Saad, A., Wakkaf, H., Bouzaiene, H., Ghalleb, M., Akaydin, E., Akbaba, A. C., Atakul, O., Baltaci, E., Besli, S., Burgu, G., Cenal, U., de Muijnck, C., Demirkaya, H. C., Dogruoz, A., Gezer, Z. I., Gundogdu, Y., Kara, M., Korkmaz, H. K., Kurtoglu, G. K., Ozben, V., Ozmen, B. B., Pektas, A. M., Sel, E. K., Yenidunya, N., Bengur, F. B., Oral, B. M., Yozgatli, T. K., Abdullayev, S., Gunes, M. E., Sahbaz, N. A., Banaz, T., Kargici, K., Kuyumcu, O. F., Yanikoglu, E., Yesilsancak, M., Yilmaz, D., Aktas, M. K., Rencuzogullari, A., Isik, A., Leventoglu, S., Yalcinkaya, A., Yuksel, O., Kalayci, M. U., Kara, Y., Sarici, I. S., Akin, A., Alemdag, G. N., Arslan, E., Baki, B. E., Bodur, M. S., Calik, A., Candas Altinbas, B., Cihanyurdu, I., Erkul, O., Gul, B., Guner, A., Kose, B., Semiz, A., Sevim, Tayar, S., Tomas, K., Tufek, O. Y., Turkyilmaz, S., Ulusahin, M., Usta, A., Yildirim, R., Guler, S. A., Tatar, O. C., Varol, E., Kirimtay, B., Uysal, M., Yildiz, A., Kose, E., Ciftci, A. B., Colak, E., Eraslan, H., Kucuk, G. O., Yemez, K., Lule, H., Bienfait, M., Bua, E., Okalany, N., Basarab, M., Bielosludtsev, O., Kolhanova, K., Perepelytsia, K., Romanukha, K., Savenkov, D., Siryi, S., Tereshchenko, M., Viacheslav, N., Volovetskyi, A., Kebkalo, A., Tryliskyy, Y., Tyselskiy, V., Bruce, E., Chow, B. L., Iddles, E., Mcguckin, S., Newall, N., Ramsay, G., Sharma, P., Stewart, C., Wong, J., Badran, A., Bath, M., Belais, F., Butt, E., Joshi, K., Kapur, M., Shaw, M., Townson, A., Williams, C. Y. K., Gray, T., Greig, R., Husain, M., Murray, E., Mustafa, A., Asif, A., Gokul, A., Shah, M., Akitikori, M. T., Charalabopoulos, A., Davidson, S., Mcnally, S., Rupani, S., Juma, F., Mills, S. C., Muirhead, L., Sellars, K., Walsh, U., Warren, O., Chambers, A., Hunt, R., Boyce, S., Cornwall, H., Tol, I., Argyriou, E. O., Eardley, N., Povey, M., Aithie, J. M. S., Irfan, A., Mcguigan, M. -C., Starr, R., Warren, C. R., Archibald, J., Kirby, G., Kisyov, I., Khoo, C. K., Lee, R., Photiou, D., Davis, R., Prasad, U., Yang, P. Z., Bird, J., Leung, E., Summerour, V., Currow, C., Kiam, J., Tan, G. J. S., Muthusami, A., Pegba-Otemolu, I., Urbonas, T., Nunoo-Mensah, J., Smolskas, E., Boddy, A., Gravante, G., Hunter, D., Andrew, D., Koh, A., Thompson, A., Adams, L., Clements, H. A., De Silva, K., Ekpete, O., Haque, S., Henderson, S., Ibrahim, B., Jayasinghe, T., Livie, J., Mailley, K., Nair, G., Tan, D., Baggaley, C., Dawidziuk, A., Szyszka, B., Barter, C., Gandhi, N., Hassell, K., Hitchin, S., Kelsall, J., Nagy, E., Nessa, A., Whisker, L., Yanni, F., Ali, M., Arora, D., Hediwattege, S., Kumarasinghe, N., Rathore, M., Tennakoon, A., Ali Ahmad, S. M., Bajomo, O., Nadira, F., Celentano, V., Griffiths, E., Karri, R. S., Mak, J. K. C., Pipe, M., Bhatti, M. I., Rabie, M., Boyle, C., Hamilton, D., Mihuna, A., Ng, J. C. K., Nicholson, G., Oliwa, A., Pearson, R., Rose, A., Yong, S. Q., Boereboom, C., Hanna, M., Walter, C., Greensmith, T. S., Mitchell, R., Monaghan, E., Crawford, J., Moug, S., Blackwell, J., Boyd-Carson, H., Herrod, P., Al-Allaf, O., Beattie, M., Bullock, C., Burman, S., Clark, G., Flamey, N., Flannery, O., Harding, A., Kodiatt, B., Lawday, S., Mahapatra, S., Mukundu Nagesh, N., Ng, M., Rye, D., Yoong, A., Clark, L., Deans, C., Edirisooriya, M., Carrington, E. V., Wong, T. L. E., Yusuf, B., Chamberlain, C., Duke, K., Kmiotek, E., Botes, A., Condie, N., Schrire, T., Shah, R., Thomas-Jones, I., Yates, C., Anthony, N., Matthews, E., Sahnan, K., Tankel, J., Tucker, S., Winter Beatty, J., Ziprin, P., Duggan, W., Kantartzi, A., Sridhar, S., Khaw, R. A., Srivastava, P., Underwood, C., Alves do Canto Brum, H., Chopra, S., Davis, L., Hughes, R., Tulley, J., Alberts, J., Athisayaraj, T., Olugbemi, M., Ahmad, K., Chan, C., Chapman, G., Fleming, H., Fox, B., Grewar, J., Hulse, K., Rutherford, D., Sinead, M., Speake, D., Vaughan-Shaw, P. G., Christodoulides, N., Kudhail, S., Welch, M., Husaini, S. M., Lambracos, S., Anyanwu, C., Suresh, R., Thomas, J. S., Gleeson, E., Platoff, R., Saif, A., Enumah, Z., Etchill, E., Gabre-Kidan, A., Bernstein, M., Carrano, F. M., Connors, J., Lynn, P., Melis, M., Newman, E., Foster, D. S., Perrone, K., Titan, A., Ahmad, S., Bafford, A. C. M. D., Dal Molin, M., Hanna, N., Zafar, S. N., Hemmila, M., Napolitano, L., Wong, J. J., Chandler, J., Wood, L., Wren, S., Ottesen, T., You, L., Yu, K., Arcienega Yanez, M. D. P., Ferreira Fernandes, M., Gonzalez, D., Cubas, S., Gonzalez, M. C., Zubiaurre, V., Demolin, R., Giroff, N., Sciuto, P., Campos, M., Rodriguez Cantera, G., Deepika, G., Simuchimba, E., Bulaya, A., Chibuye, C., Chirengendure, B., Kabale, M. -R., Kabongo, K., Munthali, J., Mweso, O., Pikiti, F., Otieno, J., Lai, L. T., Blackman, B., Subramaniam, S., Karim, R., Kok, N., Lee, Y. D., Ali, S., Sinha, A., Corrigan, R., Barnes, N., Wong, F., Dennis, G., Jedamzik, J., Phillips, E., Piette, W., Van hentenryck, M., Koco, H., Lawani, S., Kassa, M. W., Santos Bezerra, T., Gribnev, P., Dimitrov, D., Krastev, P., Oum, S., Bonghaseh, D. T., Al Farsi, M., Alsharqawi, N., Acevedo, V., Castillo Barbosa, A. C., Giron, F., Leon Rodriguez, J. P., Kucan, D., Rosko, D., Barsic, N., Zupan, D., Hegazi, A., Truncikova, V., Fryba, V., Mohamed, M., Nagi, A., Rashad Temerik, A., Elshawy, M. E., Mahmoud, M. I., Anwar, M., Rageh, T., Elmokadem, A., Gaballa, K., Teppo, S., Pengerma, P., Ballouhey, Q., Bergeat, D., Weyl, A., Hain, E., Gyedu, A., Yenli, E., Osei-Poku, D., Rompou, V. -A., Zoikas, A., Gaitanidis, A., Koukis, G., Perivoliotis, K., Tavlas, P., Galanos-Demiris, K., Zografos, G., Karavokyros, I., Xanthopoulou, G., Iordanidou, E., Ayau, F., Garcia, A., Damjan, P., Wason, D., B L, A., Rangganata, E., Kamath, P., O'Connor, D. B., Pinto, M., Perrone, F., Tropeano, F. P., Troilo, F., Bossi, D., Scala, D., Pulitano, L., Carella, M., Pietrabissa, A., Gori, A., Giraudo, G., De Simone, V., Russo, A. A., Braccio, B., Al-Taher, R., Athamneh, S., Parker, A., Sawiee, A., Kattia, A., Tababa, O., Shaeeb, Z., Syminas, V., Jurgaitis, J., Damuleviciene, G., Svagzdys, S., Razafimanjato, N. N. M., Chieng Loo, L., Tiong, I. C., Wan Muhmad, W. F., Vijeyan, H., Li Ying, T., Grech, G., Arrangoiz, R., Jimenez Ley, V. B., Arizpe, D., Lagunes Lara, E., Castro Lopez, E. V., Eaazim, J., Gordinou de Gouberville, M., Bastiaenen, V., Rottier, S., Nahab, F., Ji, M. Y., Seyoji, M., Nwachukwu, C., Emeghara, O., Muhammed, S. E., Idowu, A., Sowemimo, O., Ogundoyin, O., Akande, O., Lott, A., Nadeem, M., Laghari, A. A., Loya, A., Mushtaq, H., Abdullah, M. T., Abuhilal, B., Atawneh, M., Hamdan, H., Alhabil, B., Srour, A., Mousa, I., Da Silva Medina, L., Bartosiak, K., Ferreira, P., Francisco, V., Lemos, R., Frutuoso, L., Fernandes, S., Fonseca, T., Pereira, J., Rachadell, J., Torre, A., Madeira Martins, F., Carvalho, A. C., Rodrigues Ferreira, J., Ribeiro da Silva, B., Devesa, H., Vieira, A., Monica, I., Amaro, M., Sousa, D., Reia, M., Louro, J., Martins, A., Dominguez, J., Santos, I., Freitas Oliveira, N. M., Pereira, J. C., Silva-Vaz, P., Freire, L., Escrevente, R., Negoita, V. M., Shakhmatov, D., Nezerwa, Y., Radulovic, R., Obery, G., Viljoen, F., Mendes, T., Suarez, A., Moncada, E., Fernandez-Hevia, M., Curtis Martinez, C., Gil Garcia, J. M., Gonzalez Zunzarren, M., Idris, T., Eklov, K., Grahn, O., Amin, L., Blomqvist, M., Ajani, C., Kraus, R., Seeger, N., Willemin, M., Rayya, F., Ayash, M., Msouti, R., Kannas, I., Abazid, E., Esper, A., Slim, S., Kavcar, A. S., Aytac, E., Dural, A. C., Ilker, A., Eray, I. C., Kurnaz, E., Altiner, S., Tepe, M. D., Sahin, C., Savli, E., Innocent, A., Babirye, L., Diachenko, A., Hordoskiy, V., Curry, H., Chau, C. Y. C., Robertson, H., Lennon, H., Loi, L., Kirkham, E., Mccann, C., Watts, D., Gurung, B., Wilson, M., Tribedi, T., Garofalo, E., Zahra, B., Macdonald, S., Daniels, I., Ng, N., Khosla, S., Olivier, J., Yue, S. Y. P., Suresh, G., Wellington, J., Lorejo, E., Mossaad, M., Crutcher, M., Alimi, M., Baiu, I., Abdou, H., Conway, A., Peck, C., Perdomo Perez, M. A., Zulu, S., Nakazwe, M., Burger, S., Davies, J., Donaldson, R., Ede, C., Garden, O. J., Lesetedi, C., Mabedi, C., Magill, L., Makinde Alakaloko, F., Makupe, A., Monahan, M., Mulira, S., Muller, E., Musowoyo, J., Olory-Togbe, J. L., Roberts, T., Smith, M., Tayler, V., Windsor, J., Yepez, R., Sundar, S., Runigamugabo, E., Verjee, A., Chen, J., Daya, L., El Aroussi, N., Farina, V., Gnintedeme Olivier, T., Gonzales Nacarino, M., Hammani, A., Honjo, S., Jacobs, R., Kimura, H., Nkoronko, M., Oscullo Yepez, J. J., Pin Hung, W., Raj, A., Romani Pozo, A., Rommaneh, M., Sassamela Fabiano, S. C., Shiroma Gago, C. M., Srinivas, A., Sung, C. -Y., Tai, A., Valle Aranda, Y. C., Venturini, S., Wilguens Lartigue, J., Public and occupational health, AMS - Sports, APH - Health Behaviors & Chronic Diseases, CCA - Cancer Treatment and quality of life, Amsterdam Gastroenterology Endocrinology Metabolism, Cancer Center Amsterdam, and Albarella, Sara
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global surgery ,hospitals ,humans ,income ,neoplasms ,postoperative period ,poverty ,prospective studies ,no keywords listed ,General Medicine ,Prospective Studie ,Hospital ,Settore MED/18 - Chirurgia Generale ,outcome ,Hospitals, Humans, Income, Neoplasms, surgery, Postoperative Period, Poverty, Prospective Studies ,cancer surgery ,Human ,hospital facilities - Abstract
© 2022 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 licenseBackground: Early death after cancer surgery is higher in low-income and middle-income countries (LMICs) compared with in high-income countries, yet the impact of facility characteristics on early postoperative outcomes is unknown. The aim of this study was to examine the association between hospital infrastructure, resource availability, and processes on early outcomes after cancer surgery worldwide. Methods: A multimethods analysis was performed as part of the GlobalSurg 3 study—a multicentre, international, prospective cohort study of patients who had surgery for breast, colorectal, or gastric cancer. The primary outcomes were 30-day mortality and 30-day major complication rates. Potentially beneficial hospital facilities were identified by variable selection to select those associated with 30-day mortality. Adjusted outcomes were determined using generalised estimating equations to account for patient characteristics and country-income group, with population stratification by hospital. Findings: Between April 1, 2018, and April 23, 2019, facility-level data were collected for 9685 patients across 238 hospitals in 66 countries (91 hospitals in 20 high-income countries; 57 hospitals in 19 upper-middle-income countries; and 90 hospitals in 27 low-income to lower-middle-income countries). The availability of five hospital facilities was inversely associated with mortality: ultrasound, CT scanner, critical care unit, opioid analgesia, and oncologist. After adjustment for case-mix and country income group, hospitals with three or fewer of these facilities (62 hospitals, 1294 patients) had higher mortality compared with those with four or five (adjusted odds ratio [OR] 3·85 [95% CI 2·58–5·75]; p
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- 2022
5. Atividade física: a importância dessa pratica no envelhecimento
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Morganna Luiz Leite, Leila Batista Ribeiro, Lorena Brito Evangelista, Divinamar Pereira, Sara Fernandes Correia, Alberto César da Silva Lopes, Marcus Vinícius Ribeiro Ferreira, and Diana Ferreira Pacheco
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General Medicine - Abstract
Objetivo: descrever a importância da atividade física no envelhecimento. Método: abordagem qualitativa e o método de revisão bibliográfica integrativa. A coleta dos dados deu-se em literatura nacional indexada no banco de dados da Scielo. Foram analisados 16 artigos que atenderam aos critérios de inclusão previamente estabelecidos. Resultados: evidenciou-se que a realização de atividade física, sem dúvida age diretamente na esfera biológica do envelhecimento, trazendo benefícios aos sistemas que se comprometem na terceira idade, dentre esses se podem citar o controle da pressão arterial, a melhora da capacidade cardiovascular, respiratória, amplitude da mobilidade, menor risco de doenças, e a prevenção de alguns tipos de câncer. Conclusão: O enfermeiro da atenção básica pode se atribuir de várias metodologias de trabalho, como a formação de grupos, onde ele, articulando-se com a equipe multiprofissional, pode desenvolver tanto para os cuidadores quanto para os idosos, ações reflexivas e motivadoras, que os possibilite perceberem o envelhecimento como um processo benigno e não patológico. Descritores: Envelhecimento; Saúde do idoso; Atividade física.
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- 2023
6. Perfil de competência emocional dos enfermeiros especialistas em saúde mental e psiquiatria
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Sara Fernandes and Zélia Caçador Anastácio
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General Medicine - Abstract
O cuidar baseado nos conhecimentos científicos, do desenvolvimento de estratégias relacionais e de atitudes, bem como do desenvolvimento de um conjunto de capacidades que interagem entre si, permite ao Enfermeiro Especialista em Saúde Mental e Psiquiatria, construir relações interpessoais num ambiente afetivo estável proporcionando ao doente um cuidado diferente e peculiar. O objetivo deste estudo foi conhecer o perfil de Competência Emocional (CE) de Enfermeiros Especialistas em Saúde Mental e Psiquiatria (EESMP). A metodologia foi quantitativa tendo sido usado um questionário adaptado para esta investigação. A amostra foi do tipo bola de neve e incluiu 32 participantes, sendo maioritariamente do sexo feminino (n=26; 81,3%), com média de idades de 40 anos. Os dados foram analisados com o programa SPSS, tendo sido aplicados testes paramétricos e não paramétricos. Verificou-se que não existe relações entre as variáveis sociodemográficas e a CE. Com a variável, tempo médio diário de contacto com pessoas diagnosticadas com doença mental, obtiveram-se diferenças estatisticamente significativas na dimensão Empatia. Em relação aos determinantes da CE, confirmou-se que todas as capacidades são preditivas da mesma e que os enfermeiros especialistas apresentavam níveis moderados de CE nas suas cinco vertentes e globalmente. A dimensão “Autoconsciência”, apresentou alto nível de CE.
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- 2022
7. Greater patient sharing between hospitals is associated with better outcomes for transferred emergency general surgery patients
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Sara Fernandes-Taylor, Qiuyu Yang, Dou-Yan Yang, Bret M. Hanlon, Jessica R. Schumacher, and Angela M. Ingraham
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Surgery ,Critical Care and Intensive Care Medicine - Published
- 2022
8. PERFIL CLÍNICO-EPIDEMIOLÓGICO DEL DENGUE EN EL MUNICIPIO DE ANÁPOLIS - GOIÁS DE 2016 A 2020
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Teixeira, Larissa Schults, Mota, Mariana Santos, Oliveira, Núrya Patielly Teixeira, Negreiros, Camila Beraldo, Silva, Bruna Mendonça, Correia, Sara Fernandes, and Silva, Constanza Thaise Xavier
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Dengue ,Epidemiología ,Pruebas Serológicas ,Aedes ,Arbovirus ,General Nursing - Abstract
Objetivo: describir el perfil clínico epidemiológico del dengue en Anápolis, Goiás - BR entre los años 2016 a 2020. Métodos: estudio descriptivo de carácter cuantitativo. Se utilizaron datos de la ficha de notificación de dengue registrada en el Departamento de Vigilancia Epidemiológica. Se utilizó la prueba de chi-cuadrado con un nivel de significación del cinco (5%) (p
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- 2022
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9. Desmoid-type fibromatosis of transverse mesocolon
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Ana Catarina Martins Rodrigues, Mónica Cardoso, Duarte Gil Alves, Sara Fernandes, Maria Olim Sousa, Jorge Fernandes, Carmo Caldeira, and António Girão Caires
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General Medicine - Abstract
Desmoid tumors represent a rare disease. The recommendations for treatment and approach of these neoplasms are sparse. There are no specific imaging or clinical features which turns the diagnosis difficult. A 53-year-old male patient presented with complaints of peri-umbilical abdominal pain associated with a palpable mass. CT scan revealed a heterogeneous mass with soft tissue density and well-defined contour with approximately 8.5×7×5.3 cm localized in the mesogastric region with apparent origin in the transverse colon. The purposed etiology was of GIST. Colonoscopy was normal. The patient was submitted to surgery which revealed a mass with bright and smooth surface that was in relation with the mid portion of the transverse colon, we performed a right extended hemicolectomy. The postoperative was uneventful. Pathology evaluation revealed a desmoid-type fibromatosis. The accurate etiology of desmoid tumors is still unknown. Desmoid tumors are rare with an annual incidence of 2-4 cases per million people. They typically are slow growing fibrous soft tissue tumors with a benign behavior, however show local aggressiveness with a high ability for recurrence, complete surgical resection with clear margins is crucial.
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- 2023
10. Migrating fish bone presenting as a neck fistula
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Pedro Branco, Sara Fernandes Custódio, Pedro Sousa, and Pedro Escada
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medicine.medical_specialty ,Fistula ,Physical examination ,030218 nuclear medicine & medical imaging ,Uterine Cervical Diseases ,03 medical and health sciences ,0302 clinical medicine ,medicine ,Ingestion ,Animals ,Humans ,Surgical treatment ,Foreign Body Ingestion ,Fish bone ,medicine.diagnostic_test ,business.industry ,General Medicine ,medicine.disease ,Foreign Bodies ,Surgery ,Upper aerodigestive tract ,Aerodigestive Tract ,Seafood ,Female ,business ,030217 neurology & neurosurgery - Abstract
The case report describes an extremely rare finding of fish bone migration from the aerodigestive tract causing a neck fistula 2 years after its ingestion. Detailed case study and surgical treatment is presented. This case highlights the need for further assessment in presence of a high clinical suspicion of foreign body ingestion with a normal physical examination of the upper aerodigestive tract, to avoid serious and potential life-threatening complications later on.
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- 2023
11. Complication Rates of Total Thyroidectomy vs Hemithyroidectomy for Treatment of Papillary Thyroid Microcarcinoma: A Systematic Review and Meta-analysis
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Vivian Hsiao, Tyler J. Light, Abdullah A. Adil, Michael Tao, Alexander S. Chiu, Mary Hitchcock, Natalia Arroyo, Sara Fernandes-Taylor, and David O. Francis
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Male ,Hypoparathyroidism ,Correction ,Carcinoma, Papillary ,Observational Studies as Topic ,Otorhinolaryngology ,Thyroidectomy ,Humans ,Surgery ,Female ,Thyroid Neoplasms ,Neoplasm Recurrence, Local ,Vocal Cord Paralysis ,Original Investigation - Abstract
ImportancePapillary thyroid microcarcinomas (PTMCs) have been associated with increased thyroid cancer incidence in recent decades. Total thyroidectomy (TT) has historically been the primary treatment, but current guidelines recommend hemithyroidectomy (HT) for select low-risk cancers; however, the risk-benefit ratio of the 2 operations is incompletely characterized.ObjectiveTo compare surgical complication rates between TT and HT for PTMC treatment.Data SourcesSCOPUS, Medline via the PubMed interface, and the Cochrane Central Register of Controlled Trials (CENTRAL); through January 1, 2021, with no starting date restriction. Terms related to papillary thyroid carcinoma and its treatment were used for article retrieval. This meta-analysis used the Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) guideline and was written according to the Meta-analysis of Observational Studies in Epidemiology (MOOSE) proposal.Study SelectionOriginal investigations of adults reporting primary surgical treatment outcomes in PTMC and at least 1 complication of interest were included. Articles evaluating only secondary operations or non–open surgical approaches were excluded. Study selection, data extraction, and risk of bias assessment were performed by 2 independent reviewers and conflicts resolved by a senior reviewer.Data Extraction and SynthesisPooled effect estimates were calculated using a random-effects inverse-variance weighting model. Studies that directly compared outcomes between HT and TT were considered in a weighted meta-analysis for determination of effect sizes.Main Outcomes and MeasuresCancer recurrence and site, mortality (all-cause and disease-specific), vocal fold paralysis, hypoparathyroidism, and hemorrhage/hematoma. Risk of bias was assessed using the McMaster Quality Assessment Scale of Harms scale.ResultsIn this systematic review and meta-analysis, 17 studies were analyzed and included 1416 patients undergoing HT and 2411 patients undergoing TT (HT: pooled mean [SD] age, 47.0 [10.0] years; 1139 [84.6%] were female; and TT: pooled mean [SD] age, 48.8 [10.0] years; 1671 [77.4%] were female). Five studies directly compared outcomes between HT and TT, 5 reported solely on HT outcomes, and 7 reported solely on TT outcomes. Patients undergoing HT had significantly lower risk of temporary vocal fold paralysis compared with patients undergoing TT (2.0% vs 4.2%) (weighted risk ratio [RR], 0.4; 95% CI, 0.2-0.7), temporary hypoparathyroidism (2.2% vs 21.3%) (weighted RR, 0.1; 95% CI, 0.0-0.4), and permanent hypoparathyroidism (0% vs 1.8%) (weighted RR, 0.2; 95% CI, 0.0-0.8). Contralateral lobe malignant neoplasm recurrence was 2.4% in the HT group, while no such events occurred in the TT group. Hemithyroidectomy was associated with a higher overall recurrence rate compared with TT (3.9% vs 1.3%) (weighted RR, 2.8; 95% CI, 1.4-5.7), but there was no difference in recurrence in the thyroid bed or neck.Conclusions and RelevanceThe results of this systematic review and meta-analysis help characterize current knowledge of the risk-benefit ratio of HT vs TT for treatment of PTMC and provide data that may have utility for patient counseling surrounding treatment decisions.
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- 2023
12. Perfil de competência emocional de enfermeiros em contexto de reclusao
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Sara Fernandes and Zélia Caçador Anastácio
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General Medicine - Abstract
A vivência do cuidar da população reclusa, desenvolve-se num ambiente com características específicas, despertando nos enfermeiros sentimentos por vezes ambivalentes que estes necessitam ter a capacidade para gerir. Esta gestão, necessita do desenvolvimento de um conjunto de competências e recursos que dizem respeito à Competência Emocional. O objetivo geral deste estudo foi conhecer o perfil de competência emocional dos enfermeiros em contexto prisional e os objetivos específicos foram: apresentar as variáveis sociodemográficas da amostra, conhecer a relação entre variáveis sociodemográficas e profissionais e o perfil de competência emocional dos enfermeiros em contexto prisional. O estudo é do tipo quantitativo, de carácter descritivo e analítico. Teve como critérios de inclusão enfermeiros que trabalhavam no momento nos Estabelecimentos Prisionais do Porto, Santa Cruz do Bispo e Paços de Ferreira. O instrumento de recolha de dados foi um questionário que se encontra dividido em duas partes. A primeira parte era composta por questões que contemplam variáveis sociodemográficas e profissionais e a segunda parte foi composta pela “Escala Veiga de CE” (EVCE) (Veiga-Branco,1999). A amostra deste estudo foi constituída por 17 enfermeiros, na sua maioria do sexo feminino (52.9%). A grande maioria exercia funções no estabelecimento prisional do Porto (76.5%). Verificou-se existir relação entre a variável sociodemográfica estado civil e a dimensão Automotivação. Com a variável, tempo médio diário de contacto com reclusos também se obtiveram diferenças estatisticamente significativas nas dimensões Autoconsciência, Automotivação e Competência Emocional Global. A satisfação profissional também apresentou diferenças estatisticamente significativas em todas as variáveis dependentes, exceto na Automotivação e na Empatia. Em relação aos determinantes da Competência Emocional, confirmou-se que todas as dimensões são preditivas da mesma e que os enfermeiros apresentam níveis moderados de competência emocional nas suas cinco vertentes e globalmente. A dimensão “Autoconsciência”, apresentou alto nível de Competência emocional.
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- 2022
13. Minimally invasive treatment of pilonidal sinus disease in a paediatric population: comparison of two techniques
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Sara Fernandes, Carolina Soares‐Aquino, Inês Teixeira, Joana Mafalda Monteiro, and Miguel Campos
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Surgery ,General Medicine - Abstract
Pilonidal disease (PD) is a common and debilitating inflammatory condition with significant impact on quality of life. Minimally invasive techniques (MIT) have shown promising results comparing to traditional excision. Herein we present a comparison of two MIT techniques -sinusectomy (SE) and pit-picking plus laser ablation (PPL).All cases of paediatric PD treated by PPL and SE at our center between August 2018 and August 2020 were retrospectively reviewed.One-hundred and six patients were included, with a median age of 16 years (IQR 15-16). PPL was the procedure of choice in 36 patients (34%) and the remaining underwent SE (66%). Median healing time was significantly lower in SE group (20 days), comparing to PPL (30 days) (p = 0.002). Early healing failure occurred more frequently in the PPL group (p = 0.003). Recurrence rate was similar between groups - PPL 17% versus SE 16% (p = 0.89). Overall complication rate was 9% and was significantly higher in PPL (p = 0.03).MIT techniques are promising solutions in PD treatment. Although similarly easy and fast to perform, SE technique showed better healing profile and lower complication rate but no significant difference on recurrence rates was observed.
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- 2022
14. Concerns Over Diagnostic Accuracy of Fine-Needle Biopsy in Thyroid Nodule Diagnosis—Reply
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Vivian Hsiao, Sara Fernandes-Taylor, and David O. Francis
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Surgery - Published
- 2023
15. Herpes simplex virus esophagitis-clinical challenges in the elderly
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Sara Fernandes Custódio, Fátima Cruz, Manuela Zita Veiga, and Catarina Félix
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medicine.medical_specialty ,Abdominal pain ,Acyclovir ,Case Report ,Anorexia ,medicine.disease_cause ,Esophageal Diseases ,Gastroenterology ,Malaise ,03 medical and health sciences ,0302 clinical medicine ,Internal medicine ,medicine ,Esophagitis ,Humans ,Simplexvirus ,Aged ,business.industry ,Herpes Simplex ,General Medicine ,medicine.disease ,Dysphagia ,Herpes simplex virus ,030220 oncology & carcinogenesis ,Vomiting ,030211 gastroenterology & hepatology ,Female ,Liver function ,medicine.symptom ,business - Abstract
A 77-year-old woman presented with a 2-week history of malaise, prostration, anorexia, abdominal pain, vomiting and diarrhoea. She had been taking systemic corticosteroids for the past year. During hospitalisation, renal insufficiency, ionic changes and liver function abnormalities were detected and corrected. However, the patient developed total dysphagia. UGE revealed multiple shallow ulcers below the cricopharyngeal level and in the distal oesophagus, with normal-appearing intervening mucosa. Histological examination allowed the diagnosis of herpes simplex virus esophagitis. Treatment with intravenous acyclovir was instituted for 14 days. In the elderly, herpetic esophagitis may present with non-specific complains, such as prostration or anorexia. In the reported case, dysphagia was only detected as a late symptom, addressing the importance of maintaining a high degree of suspicion for the diagnosis of herpes simplex virus esophagitis.
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- 2023
16. Central Nervous System Source Modulates Microglia Function and Morphology In Vitro
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Andreia G Pinho, Andreia Monteiro, Sara Fernandes, Nídia De Sousa, António Salgado, Nuno A. Silva, and Susana Monteiro
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neuroscience_and_neurology_130 - Abstract
Regional heterogeneity of microglia was first described a century ago by Pio del Rio Hortega. Currently, new hints on microglia heterogeneity across central nervous system (CNS) regions are still being unraveled by high-throughput techniques. It remains unclear whether these spatial specificities translate into different microglial behaviors in vitro. We cultured microglia isolated from the cortex and spinal cord and analyzed the effect of the CNS spatial source on in vitro behavior by applying the same experimental protocol and culture conditions. We analyzed microglial cell numbers, function, and morphology and found a distinctive in vitro phenotype. We found that microglia were present in higher numbers in spinal cord-derived glial cultures, presenting different expression of inflammatory genes and a lower phagocytosis rate under basal conditions or after activation with LPS and IFN-. Morphologically, cortical microglial cells are more complex and present longer ramifications, which were also observed in vivo in CX3CR1+/GFP transgenic reporter mice. Collectively, our data demonstrated that microglial behavior in vitro is defined according to specific spatial characteristics acquired in the tissue. Thus, our study highlights the importance of microglia as a source of CNS for in vitro studies.
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- 2023
17. Can Superhydrophobic PET Surfaces Prevent Bacterial Adhesion?
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Tugce Caykara, Sara Fernandes, Adelaide Braga, Joana Rodrigues, Ligia R. Rodrigues, and Carla Joana Silva
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General Chemical Engineering ,nanoparticles ,surface modification ,polyethylene terephthalate ,superhydrophobic ,bacterial adhesion ,General Materials Science - Abstract
Prevention of bacterial adhesion is a way to reduce and/or avoid biofilm formation, thus restraining its associated infections. The development of repellent anti-adhesive surfaces, such as superhydrophobic surfaces, can be a strategy to avoid bacterial adhesion. In this study, a polyethylene terephthalate (PET) film was modified by in situ growth of silica nanoparticles (NPs) to create a rough surface. The surface was further modified with fluorinated carbon chains to increase its hydrophobicity. The modified PET surfaces presented a pronounced superhydrophobic character, showing a water contact angle of 156° and a roughness of 104 nm (a considerable increase comparing with the 69° and 4.8 nm obtained for the untreated PET). Scanning Electron Microscopy was used to evaluate the modified surfaces morphology, further confirming its successful modification with nanoparticles. Additionally, a bacterial adhesion assay using an Escherichia coli expressing YadA, an adhesive protein from Yersinia so-called Yersinia adhesin A, was used to assess the anti-adhesive potential of the modified PET. Contrarily to what was expected, adhesion of E. coli YadA was found to increase on the modified PET surfaces, exhibiting a clear preference for the crevices. This study highlights the role of material micro topography as an important attribute when considering bacterial adhesion.
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- 2023
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18. Caracterização e análise de desempenho logístico: uma análise da empresa Steelgreen, S.A
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Sousa, Sara Fernandes and Alves, Wellington
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Logística ,Dashboards ,Logistics ,Indicadores de desempenho ,Evaluation ,Performance Indicators ,Avaliação - Abstract
Dissertação de Mestrado apresentado à Escola Superior de Ciências Empresariais do Instituto Politécnico de Viana do Castelo para a obtenção do Grau de Mestre em Logística (APNOR) O mercado empresarial é conhecido por ser muito competitivo, e em cada operação é fulcral a obtenção de uma margem de lucro que permita a durabilidade da organização. Desta forma, para que seja possível crescer de forma eficiente é necessário a implementação e utilização de indicadores para que a empresa tenha uma visão clara do seu desempenho e possa desse modo agir de forma eficaz. Este projeto tem como principal objetivo analisar o atual cenário logístico de uma indústria metalúrgica, recorrendo a um conjunto de indicadores de desempenho logístico. Na realização deste estudo propõe-se ainda o desenvolvimento de uma ferramenta de avaliação de desempenho tendo como base um conjunto de KPI’s, que permita identificar à organização os métodos para melhorar possíveis baixos índices de desempenho nas diferentes áreas da logística. A metodologia de investigação a ser aplicada compreenderá uma abordagem mista, uma vez que, foram analisados os indicadores de forma qualitativa, através da investigação desenvolvida e, quantitativa através dos cálculos dos diversos indicadores de desempenho logístico. Através dos resultados é possível observar que a melhor dimensão seria a das Entregas, uma vez que, foi a dimensão analisada mais detalhadamente. Os pontos fortes encontrados nesta dimensão foram os Indicadores do Índice de Atendimento do Pedido, Tempo de Ciclo do Pedido e o da Devolução dos Pedidos. Em suma, quanto às outras dimensões (Stock e Transporte) é de realçar que a falta de dados relativamente ao setor financeiro, mas também ao facto de se tratar de um serviço de transporte subcontratado impossibilitou uma análise mais aprofundada destas dimensões. The business market is known to be very competitive, and in each operation, it is essential to obtain a profit margin that allows the organization to last. In this way, in order to be able to grow efficiently, it is necessary to implement and use indicators so that the company has a clear view of its performance and can therefore act effectively. The main objective of this project is to analyze the current logistical scenario of a metallurgical industry, using a set of logistical performance indicators. In carrying out this study, it is also proposed the development of a performance evaluation tool based on a set of KPI's, which allows the organization to identify the methods to improve possible low performance indices in the different areas of logistics. The research methodology to be applied will comprise a mixed approach, since the indicators were analyzed qualitatively, through the research carried out and, quantitatively, through the calculations of the various logistics performance indicators. Through the results it is possible to observe that the best dimension would be Deliveries, since it was the dimension analyzed in more detail. The strengths found in this dimension were the Order Fulfillment Index Indicators, Order Cycle Time, and Order Return Time. In short, regarding the other dimensions (Stock and Transport) it should be noted that the lack of data regarding the financial sector, but also the fact that it is a subcontracted transport service, made it impossible to carry out a more in-depth analysis of these dimensions.
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- 2023
19. The invisible work of transfer centre nurses: A qualitative study of strategies to overcome communication challenges
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Megan C. Saucke, Esra Alagoz, Natalia Arroyo, Diana E. Gutierrez‐Meza, Sara Fernandes‐Taylor, and Angela M. Ingraham
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General Nursing - Published
- 2023
20. The Use of a Polylactic Membrane in Pediatric Burns Proves to be Successful Even After Late Application
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Sara Fernandes, Inês Teixeira, Leonor Carmo, Miguel Campos, and Maria Garcia
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Rehabilitation ,Emergency Medicine ,Surgery - Abstract
The Polylactide membrane (PLM) is a biosynthetic dressing that mimics properties of the human epithelium. Herein we describe our experience on the use of PLM in pediatric burns. All pediatric burn patients admitted to the Pediatric Surgery Department between November 2019 and November 2021 and submitted to PLM application were selected. Clinical and demographic data were collected retrospectively. Seventy-seven patients with a median age of 1.8 years were included. The median total body surface area was 6% (2–20%), and burns were mainly mixed-partial thickness. PLM was applied at a median of 5 days post-burn (IQR 3–6), usually under sedation (43/77). After PLM application, the median healing time (HT) was 10 days (IQR 8–14). HT was significantly higher in deep-partial thickness burns vs. mixed superficial-deep (P = .015) and superficial burn areas (P = .006). No correlation was found between HT and the timing of PLM application. The grafting rate due to clinical misevaluation was 2.7%, one infection was found. The PLM is a promising way for treating partial-thickness burns, even when applied later during treatment. Shorter HT, the decreased need for dressing changes, and the potential of sparing of donor sites and pain reduction are its main advantages.
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- 2023
21. Torsion of undescended testicle in an adolescent: A rare challenging surgical emergency☆
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Inês Paiva Ferreira, Diana Alba, Sara Fernandes, Tiago Tuna, Tiago Branco, and Jorge Abreu Ferreira
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Pediatrics, Perinatology and Child Health - Published
- 2023
22. Plasmaferese Terapêutica: Experiência de Sete Anos de um Serviço de Medicina Intensiva em Portugal
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André Carrão, António Messias, André Gordinho, Luis Falcao, Sara Fernandes, Carlos Meneses-Oliveira, Alexei Bucur, Rita Faria, and João Colaço
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Male ,medicine.medical_specialty ,medicine.medical_treatment ,Therapeutic Procedure ,law.invention ,law ,medicine ,Humans ,Critical Illness/therapy ,Plasma Exchange/methods ,Plasmapheresis/adverse effects ,Plasmapheresis/methods ,Plasmapheresis /therapeutic use ,Retrospective Studies ,Plasma Exchange ,Portugal ,business.industry ,Retrospective cohort study ,Plasmapheresis ,Estado Crítico/tratamento ,Plasmafere/efeitos adversos ,Plasmafere/métodos ,Plasmafere/uso terapêutico ,Troca Plasmática/métodos ,General Medicine ,Middle Aged ,medicine.disease ,Intensive care unit ,Intensive Care Units ,Emergency medicine ,Pancreatitis ,Observational study ,Fresh frozen plasma ,Vasculitis ,business - Abstract
Therapeutic plasmapheresis is a therapeutic procedure in which the patient's blood is passed through a medical device which separates out plasma from other components of blood. The plasma is removed and replaced with a replacement solution. Studies on the use of plasmapheresis in critically ill patients are scarce. The aim of this study was to review all therapeutic plasmapheresis sessions carried out in the Hospital Beatriz Ângelo intensive care unit.An observational retrospective study was conducted between April 2012 and March 2019. All patients who underwent therapeutic plasmapheresis in the intensive care unit were included, and plasmapheresis sessions held outside the intensive care unit were excluded.Of 46 patients, 63% were men (n = 29), with a median age of 53 years. The most frequent diagnoses were hypertriglyceridemia-induced pancreatitis, vasculitis, autoimmune haemolytic anaemia, and atypical haemolytic-uremic syndrome. A total of 198 plasmapheresis sessions were carried out in the intensive care unit. Most of the used replacement solutions were fresh frozen plasma (34.4%), albumin/crystalloid (24.2%), and albumin/fresh frozen plasma (19.2%). The most common complications were hydroelectrolytic changes (84; 42.4%) and coagulation disorders/thrombocytopenia (65; 32.8%). There was no need to interrupt any plasmapheresis session due to complications related to the patient.Therapeutic plasmapheresis is an urgent procedure that can reduce morbidity and mortality in critically ill patients. This justifies that 37% of patients started the technique before the diagnostic confirmation. The indications for plasmapheresis and the choice of replacement solution were in agreement with the guidelines. Despite the risk of bleeding, no haemorrhagic complications were recorded.Therapeutic plasmapheresis is a complex technique that requires specific training. The indications are diverse, and some are not consensual. Complications were frequent, but they did not increase morbidity.Introdução: A plasmaferese terapêutica é um procedimento em que o sangue passa por um circuito extracorpóreo que separa o plasma dos outros componentes do sangue. O plasma removido é substituído por soluções de reposição. Os estudos sobre a utilização de plasmaferese terapêutica no doente crítico são escassos. O objetivo do estudo foi rever todas as sessões de plasmaferese realizadas no serviço de Medicina Intensiva do Hospital Beatriz Ângelo. Material e Métodos: Estudo observacional retrospetivo de todos os doentes admitidos no serviço de Medicina Intensiva entre abril de 2012 e março de 2019. Foram selecionados os doentes submetidos a plasmaferese e excluídas as sessões realizadas fora do serviço de Medicina Intensiva. Resultados: No período de estudo foram incluídos 46 doentes. A maioria eram homens (n = 29; 63%) com uma idade mediana de 53 anos. Os diagnósticos mais frequentes foram pancreatite secundária a hipertrigliceridemia, vasculite, anemia hemolítica autoimune e síndrome hemolítica urémica atípica. Foram realizadas 198 sessões de plasmaferese no serviço de Medicina Intensiva. As soluções de substituição mais utilizadas foram plasma fresco congelado (34,4%), albumina/cristalóide (24,2%) e albumina/plasma (19,2%). As complicações mais comuns foram alterações hidroeletrolíticas (84; 42,4%), e distúrbios da coagulação/plaquetas (65; 32,8%). Em nenhum dos casos a técnica teve que ser interrompida por complicações relacionadas com o doente. Discussão: A plasmaferese terapêutica é um procedimento urgente capaz de reduzir a morbilidade e mortalidade no doente crítico. Isto justifica que 37% dos doentes tenham iniciado a técnica antes da confirmação diagnóstica. As indicações e soluto de reposição escolhido foram de acordo com as recomendações. Apesar do risco hemorrágico, nenhuma complicação desta natureza foi reportada. Conclusão: A plasmafere terapêutica é uma técnica complexa que requer treino específico. As indicações são diversas e algumas não consensuais. As complicações foram frequentes, mas não condicionaram morbilidade associada.
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- 2022
23. Perpetual Becoming, Deferred Arrival: The Author-Hero in the Age of Digital Celebrity
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Sara Fernandes and Lydia Saleh Rofail
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Literature and Literary Theory - Published
- 2022
24. Thoracic Outlet Syndrome after Minimally Invasive Repair of Pectus Excavatum in a 15-Year-Old Boy: A Case Report
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Sara Fernandes, Carolina Soares-Aquino, Joana Monteiro, Norberto Estevinho, and Mariana Borges-Dias
- Abstract
Nuss procedure has become the treatment of choice in pectus excavatum mainly because of the excellent functional and cosmetic results. Despite the good results, several complications have been reported. The aim of this study is to describe a case of thoracic outlet syndrome (TOS) after Nuss procedure and review the management of such rare complication. A 15-year-old boy otherwise healthy was submitted to Nuss procedure, with no perioperative complications. Two-weeks later, the patient complained of right-hand paresthesia, progressive weakness of the right arm and coldness. After imaging and electromyography, TOS diagnosis was established. Removal of the bar was proposed but refused by the patient. Conservative management with rehabilitation exercising and nerve nourishing was initiated. At 7 months, the patient recovered arm and hand function. Abrupt structural changes of thoracic cavity with marked elevation of the upper chest induce nerve and vascular compression arousing a TOS and should be acknowledged as one potential complication of Nuss procedure. Conservative management can be an alternative treatment to bar removal, showing good results on functional recovery in early stages of compression.
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- 2022
25. Notas sobre a Visão Pagã do Mundo
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Carlos Correia and Sara Fernandes
- Published
- 2022
26. Symptoms of anxiety and depression in patients with persistent asthma : a cross-sectional analysis of the INSPIRERS studies
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Mafalda Simões Cunha, Rita Amaral, Ana Margarida Pereira, Rute Almeida, Magna Alves-Correia, Cláudia Chaves Loureiro, Cristina Lopes, Joana Carvalho, Carmelita Ribeiro, Carmen Vidal, Dario Antolín-Amérigo, Diana Pinto, Manuel Ferreira-Magalhães, Maria João Vasconcelos, Carlos Lozoya, Natacha Santos, Francisca Cardia, Luís Taborda-Barata, Rosário Ferreira, Pedro Morais Silva, Tania Monteiro Ferreira, Raquel Câmara, Eurico Silva, Diana Bordalo, Cristina Guimarães, Maria José Calix, Sofia da Silva, Maria Luís Marques, Ana Morete, Carlos Nunes, Cláudia Vieira, Rosália Páscoa, Adelaide Alves, José Varanda Marques, Bruno Reis, Luís Monteiro, Rosário Monteiro, Margarida Cepa, Bruno Valentim, Daniela Sousa Coelho, Sara Fernandes, Patrícia Meireles, Margarida Abreu Aguiar, Ana Rita Mourão, Joao A Fonseca, and Cristina Jácome
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Psychiatry ,anxiety disorders ,Respiratory Medicine and Allergy ,depression & mood disorders ,General Medicine ,asthma ,Psykiatri ,Lungmedicin och allergi - Abstract
ObjectivesAnxiety and depression are relevant comorbidities in asthma, but, in Portugal and Spain, data on this topic are scarce. We assessed, in patients with asthma, the frequency of anxiety and depression using the Hospital Anxiety and Depression Scale (HADS) and the European Quality of Life Five Dimension Questionnaire (EQ-5D); the level of agreement between these questionnaires, and the factors associated with these symptoms.MethodsThis is a secondary analysis of the INSPIRERS studies. A total of 614 adolescents and adults with persistent asthma (32.6±16.9 years, 64.7% female) were recruited from 30 primary care centres and 32 allergy, pulmonology and paediatric clinics. Demographic and clinical characteristics, HADS and EQ-5D were collected. A score ≥8 on Hospital Anxiety and Depression Scale-Anxiety/Hospital Anxiety and Depression Scale-Depression or a positive answer to EQ-5D item 5 indicated the presence of these symptoms. Agreement was determined by Cohen’s kappa. Two multivariable logistic regressions were built.ResultsAccording to HADS, 36% of the participants had symptoms of anxiety and 12% of depression. According to EQ-5D, 36% of the participants had anxiety/depression. The agreement between questionnaires in identifying anxiety/depression was moderate (k=0.55, 95% CI 0.48 to 0.62). Late asthma diagnosis, comorbidities and female gender were predictors of anxiety/depression, while better asthma control, health-related quality of life and perception of health were associated with lower odds for anxiety/depression.ConclusionAt least 1/3 of the patients with persistent asthma experience symptoms of anxiety/depression, showing the relevance of screening these disorders in patients with asthma. EQ-5D and HADS questionnaires showed a moderate agreement in the identification of anxiety/depression symptoms. The identified associated factors need to be further investigated in long-term studies.
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- 2023
27. Sparsentan in patients with IgA nephropathy: a prespecified interim analysis from a randomised, double-blind, active-controlled clinical trial
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Hiddo J L Heerspink, Jai Radhakrishnan, Charles E Alpers, Jonathan Barratt, Stewart Bieler, Ulysses Diva, Jula Inrig, Radko Komers, Alex Mercer, Irene L Noronha, Michelle N Rheault, William Rote, Brad Rovin, Howard Trachtman, Hernán Trimarchi, Muh Geot Wong, Vlado Perkovic, Eric Alarmartine, Dong Wan Chae, Lucia Del Vecchio, Jurgen Floege, Shang-Jyh Hwang, Bojan Jelakovic, Bart Maes, Robert Malecki, Marius Miglinas, Fernando Eduardo Barbosa Nolasco, Manual Praga, Kannaiyan Rabindranath, Mai Rosenberg, Sydney Chi Wai Tang, Vladmir Tesar, Bhadran Bose, Muralikrishna Gangadharan, Stephen McDonald, Chen Peh, Sadia Jahan, Chii Yeap, Philip Clayton, Georgina Irish, Nikhil Thyagarajan, Peter Hollett, Rathika Krishnasamy, Robert Carroll, Shilpanjali Jesudason, Susan Crail, Toby Coates, Jane Waugh, Euan Noble, Kumaradevan Mahadevan, Victoria Campbell, Tania Salehi, Wai Lim, Neil Boudville, Aron Chakera, Doris Chan, Anoushka Krishnan, Yusuf Eqbal, Alastair Gillies, Eswari Vilayur, Thida Maung Maung Myint, Nicholas Gray, Melissa Cheetham, Carol Pollock, Bruce Cooper, Amanda Mather, Sarah Roxburgh, Yvonne Shen, Stefanie Stangenberg, Amanda Siriwardana, Emma O'Lone, Susan Wan, Brendon Neuen, Jeffrey Tsun Kit Ha, Dana Kim, Lauren Heath, Arunima Jain, Elaine Phua, Yan Li, Martin Gallagher, Meg Jardine, Angus Ritchie, Mona Razavian, Celine Foote, Roger Wyndham, Shaundeep Sen, Zoltan Endre, Jonathan Erlich, Mangalee Fernando, Kenneth Yong, Grant Luxton, Sradha Kotwal, Simon Roger, Vidu Wijeratne, David Packham, Ian Fraser, Bert Vandewiele, Margo Laute, Wim Lemahieu, Sofie Jamar, Sara Ombelet, Gert Meeus, Marc Decupere, Olivier Schockaert, Peter Doubel, Liesbeth Viaene, Luc Radermacher, Catherine Masset, Martial Moonen, Eric Firre, Martina Milicevic, Xavier Warling, An Vanacker, Thomas Malfait, Ivan Durlen, Ivica Horvatic, Ana Savuk, Lana Gellineo, Sandra Karanovic, Zivka Dika, Djuro Plavljanic, Ivana Mikacic, Dubravka Trajbar Kentric, Dunja Barisic, Marija Stankovic, Karolina Majstorovic Barac, Ivan Kruljac, Drasko Pavlovic, Martin Drinkovic, Ingrid Prkacin, Jerko Barbic, Zvonimir Sitas, Dunja Vujcic, Ivan Rychlik, Anna Benesova, Klara Drinovska, Karolina Kratka, Dita Maixnerova, Madis Ilmoja, Kristin Unt, Kadri Lilienthal, Asta Auerbach, Liisi Leis, Julia Piel, Annika Adoberg, Kulli Kolvald, Kristi Veermae, Kadri Telling, Elviira Seppet, Jana Uhlinova, Philippe Zaoui, Pierre-Louis Carron, Ingrid Masson, Miriana Dinic, Damien Thibaudin, Christian Broyet, Nicolas Maillard, Hesham Mohey, Christophe Mariat, Guillaume Claisse, Eric Alamartine, Bertrand Dussol, Stephane Burtey, Noemie Chiche-Jourde, Jean-Emmanuel Serre, Guillaume Jeantet, Leila Chenine, Anne Blanchard, Stephane Roueff, Eric Thervet, David Fouassier, Alexandre Buffet, Marine Livrozet, Roxane Gaisset, Alexandre Karras, Anne-Elisabeth Heng, Cyril Garrouste, Carole Philipponnet, Clementine Nicolo, Alba Atenza, Camille Lanaret, Clarisse Greze, Valentin Mayet, Clement Dumond, Yahsou Delmas, Christian Combe, Claire Rigothier, Laure Burguet, Aurore Labat, Simon Mucha, Valérie de Précigout, Thomas Weinreich, Helmut Reichel, Diliana Draganova, Lothar Wolf, Bernd Hohenstein, Sven Heinrichs, Simone Kulka, Sebahat Sat, Lea Weiland, Thilo Krueger, Gunter Wolf, Christiane Kettner, Mandy Schlosser, Johann Konstantin Herfurth, Annegret Koch, Martin Busch, Stephan Christian Werth, Martin Nitschke, Figen Cakiroglu, Franziska Sarnow, Lisa Schulz, Stefan Weiner, Nikolaus Wirtz, Eric Koester, Marcus Moeller, Eleni Stamellou, Silja Sanden, Hans Schmidt-Guertler, Wanja Bernhardt, Margret Patecki, Georg Schlieper, Kevin Schulte, Annette Girardet, Ulrich Kunzendorf, Lorraine Pui Yuen Kwan, Maggie Ming Yee Mok, Gary Chi Wang Chan, Mingyao Ma, Davina Ngoi Wah Lie, Anthony Ting Pong Chan, Cheuk Chun Szeto, Kit Chung Jack Ng, Siu Fai Cheung, Tak Tai Andrew Yue, Ka Shun Samuel Fung, Hon Tang, Ka Fai Yim, Wai Ping Law, Yick Hei Wong, Chi Kwan Darwin Lam, Sze Ho Sunny Wong, Carmelita Marcantoni, Roberta Aliotta, Francesca Deodato, Gemma Patella, Nicolino Comi, Caterina Vita, Nazareno Carullo, Davide Bolignano, Michela Musolino, Matias Trillini, Norberto Perico, Giuseppe Remuzzi, Erica Daina, Luigi Biancone, Loredana Colla, Manuel Burdese, Chiara Cogno, Elena Boaglio, Isabella Abbasciano, Carlotta Federica Zizzi, Paolo Randone, Pietro Napodano, Anna Ricchiuto, Matthias Cassia, Simone Accarino, Mario Cozzolino, Rocco Baccaro, Stefano Costanzi, Federica Di Maio, Maria Arena, Federica Urciuolo, Sara Vigano, Andrea Cavalli, Monica Limardo, Monica Bordoli, Serena Ponti, Selena Longhi, Andrea Solazzo, Francesco Giaroni, Gabriele Donati, Massimo Torreggiani, Davide Catucci, Marco Colucci, Vittoria Esposito, Ciro Esposito, Loreto Gesualdo, Flavia Capaccio, Emma Diletta Stea, Carmen Sivo, Francesca Annese, Federica Papadia, Piergiorgio Messa, Mirco Belingheri, Patrizia Passerini, Silvia Malvica, Alvita Vickiene, Urte Zakauskiene, Egle Asakiene, Inga Arune Bumblyte', Asta Stankuviene, Lina Santockiene, Ashik Hayat, Allister Williams, Peter Sizeland, Eddie Tan, Gerald Waters, Lai Wan Chan, Andrew Henderson, Angus Turnbull, Andrew McNally, Annie Reynolds, Helen Pilmore, Ian Dittmer, Paul Manley, Elizabeth Stallworthy, Tze Goh, David Semple, Michael Collins, Elizabeth Curry, Jafar Ahmed, Thu Nguyen, Agata Winiarska, Justyna Zbrzezniak, Tomasz Stompor, Magdalena Krajewska, Hanna Augustyniak-Bartosik, Dorota Zielinska, Anna Jander, Malgorzata Stanczyk, Marcin Tkaczyk, Przemyslaw Miarka, Dariusz Aksamit, Piotr Jaskowski, Wladyslaw Sulowicz, Dominik Cieniawski, Julita Gontarek-Kacprzak, Elzbieta Felicjanczuk, Norbert Kwella, Bogna Kwella, Ewa Satora, João Carlos Fernandes, Ana Marta Gomes, Marina Reis, Daniela Lopes, Catarina Almeida, Helena Sá, Ana Carolina Figueiredo, Clara Pardinhas, Edgar Almeida, Mario Raimundo, Ana Cortesão Costa, Luis Pedro Falcao Goncalves, Sara Fernandes, Sónia Silva, Catarina Teixeira, Adriana Fernandes, Fernando Nolasco, Patricia Alves, Mario Gois, Nuno Fonseca, Ana Messias, Maria Menezes, Filipa Cardoso, Helena Sousa, Joana Marques, Rui Barata, Jose Antonio Lopes, Sofia Jorge, Joana Gameiro, Jose Nuno de Almeida Agapito Fonseca, Sara Goncalves, Ana Farinha, Patricia Valerio Santos, Ana Natario, Jose Carlos de Jesus Barreto, Catarina Abrantes, Elsa Sofia Quadrado Soares, Joana de Sousa Soares Felgueiras, Liliana Cunha, Lucia Parreira, Teresa Furtado, Alvaro Vaz, Kook-Hwan Oh, Hajeong Lee, Se Joong Kim, Jong Cheol Jeong, Yeong Hoon Kim, Yunmi Kim, Hyeong Cheon Park, Hoon Young Choi, Hyung Wook Kim, Moon Hyoung Lee, Songuk Yoon, Kyu-Beck Lee, YoungYoul Hyun, Tae-Hyun Yoo, Seung Hyeok Han, Jung Tak Park, Sunggyun Kim, Young Rim Song, Jwa-Kyung Kim, Hyung-seok Lee, Narae Joo, JungEun Lee, Hye Ryoun Jang, Junseok Jeon, Wookyung Chung, HyunHee Lee, Jae Hyun Chang, Ka Yeong Chun, Ji Yong Jung, Han Ro, Aejin Kim, Sang-Kyung Jo, Jihyun Yang, Myung-Gyu Kim, SeWon Oh, Caridad Martinez Villanueva, Ana Vilar Gimeno, Gustavo Andres Useche Bonilla, Esther Tamarit, Antonio Galan Serrano, Eduardo Verde Moreno, Jose Luño Fernandez, Maria Angeles Goicoechea Diezhandino, Ursula Verdalles Guzman, Ana Perez de Jose, Alberto Ortiz Arduan, María Vanessa Pérez Gómez, Catalina Martín Cleary, Raul Fernandez Prado, Elena Goma, Jose Ballarin, Montserrat Diaz Encarnacion, Iara Da Silva Santos, Helena Marco Rusinol, Monica Furlano, Carlos Arias, Clara Barrios, Eva Rodriguez Garcia, Adriana Sierra Ochoa, Belen Vizcaino Castillo, Jonay Pantoja Perez, Mercedes Gonzalez Moya, Mari Sargsyan, Emma Calatayud Aristoy, Ana Avila Bernabeu, Leticia Perez Lluna, Tamara Malek Marin, Maria Antonia Munar Vila, Ivon Maritza Bobadilla Rico, Natalia Allende Burgos, Eduardo Gutierrez Martinez, Elena Gutierrez Solis, Angel Sevillano, Evangelina Merida Herrero, Josep Miquel Blasco Pelicano, Lida Maria Rodas Marin, Luis F Quintana, Maria Antonieta Azancot Rivero, Natalia Ramos Terrades, Clara Garcia Carro, Irene Agraz Pamplona, Mercedes Salgueira Lazo, Francisco de la Prada Alvarez, Fabiola Alonso Garcia, Wenceslao Adrian Aguilera Morales, Salia Virxinia Pol Heres, Angel Forcen, Eduardo Parra Moncasi, Cristina Medrano Villarroya, Alejandro Soria Villen, Olga Gracia Garcia, Mercedes Velo Plaza, Maria Dolores Sánchez de la Nieta, Marta Calvo Arevalo, Antolina Moreno, Secundino Cigarran Guldris, Manuel Pereira de Vicente, Bang-Gee Hsu, Chih-Hsien Wang, Cheng-Hsu Chen, Tung-Min Yu, Ming-Ju Wu, Shang-Feng Tsai, Chia-Tien Hsu, Hsien-Fu Chiu, Kang-Ju Chou, Hua-Chang Fang, Po-Tsang Lee, Hsin-Yu Chen, Chien-Liang Chen, Chien-Wei Huang, Shih-Hsiang Ou, Tzung-Yo Ho, Chih-Yang Hsu, Ming-Shan Chang, Yen-Ling Chiu, Yu-Sen Peng, Kai-Hsiang Shu, Szu-Yu Pan, Shih-Ping Hsu, Ju-Yeh Yang, Mei-Fen Pai, Po-Yu Tseng, Hon-Yen Wu, Wan-Chuan Tsai, Kuei-Ting Tung, Hung-Yuan Chen, Hung-Chun Chen, Mei-Chuan Kuo, Daw-Yang Hwang, Yi-Wen Chiu, Chi-Chih Hung, Hung-Tien Kuo, Jer-Chia Tsai, Kieran McCafferty, Suzanne Forbes, Indranil Dasgupta, Mark Thomas, Amar Mahdi, Bamidele Ajayi, Paramit Chowdhury, Theodoros Kasimatis, Dimitrios Moutzouris, Caroline Dudreuilh, Rishi Pruthi, Nick Mansfield, Gabriel Doctor, Sapna Shah, Sui Kon, Priscilla Smith, Patrick Hamilton, Durga Kanigicherla, Omar Sherin Ibrahim Ragy, Bassam Alchi, Oliver Flossmann, Farid Ghalli, Sarah Lawman, Smeeta Sinha, Constantina Chrysochou, Chukwuma Chukwu, Aine Maire De Bhailis, Saif Al Chalabi, Amy Hudson, Arun Gopu, Olivia Wickens, Joshua Storrar, Mona Wahba, Nathan Lorde, Mohammad Rony, Sian Griffin, Farah Latif, Mohammad Ali, Louise DaSilva, Jonathan Ayling-Smith, Eamon Mahdi, Lisa Willcocks, Rachel Jones, Chee Kay Cheung, Haresh Selvaskandan, Dan Pugh, Matthew Sayer, Neeraj Dhaun, Fiona Chapman, Patrick Mark, Colin Geddes, Emily McQuarrie, Rajan Patel, Laurence Solomon, Arvind Ponnusamy, Adam Morris, Pedro Okoh, Lauren Floyd, Ajay Dhaygude, Janson Leung, Christopher Goldsmith, Bhavna Pandya, Didem Tez, Ashraf Mikhail, Karen Brown, Thomas Bucknall, Mark Lambie, Roderick Comunale, Donald Brandon, Stacy Martinez, Amanda Hall, Amy Henderson, Aaron Fearday, Nicole Douthit, Brian Snow, Arnold Silva, Cathylee Sly, Christopher Keller, Robert Davidson, Jerry Meng, Robert Haws, Siddhartha Kattamanchi, Javad Mojarrab, Unnikrishnan Pillai, Richard Lafayette, Michelle O'Shaughnessy, Fahameedah Kamal, Kshama Mehta, Bruce Baker, Mario Ruiz, Praveena Jyothinagaram, Usha Peri, William Paxton, James Tumlin, Kerri McGreal, Ellen McCarthy, Cassandra Kimber, Archana Gautam, Kassem Khalil, Viet Nguyen, Raffi Minasian, Dariush Arfaania, Sam Daneshvari, Michel Zakari, Artashes Patrikyan, Rouzbeh Afsari, Christine Ayvazyan, Faisal Fakih, Mark Lagatta, Alfred Rodriguez, Jorge Enrique Monroy Avella, Ramachandra Patak, Jigar Kadakia, Gerald Appel, Wooin Ahn, Bradley Nelson, Allyson Medina, Syeda Ahmad, Yonatan Peleg, Nisha Clement, Ian Chiu, Elizabeth Hendren, Andrew Bomback, Pietro Canetta, Bruce Spinowitz, Chaim Charytan, Nishita Parikh, Sheng Kuo, Ritesh Raichoudhury, Mirela Dobre, Lavinia Negrea, Aparna Padiyar, Arksarapuk Jittirat, Nishigandha Pradhan, Ranjit Dhelaria, Saravanan Balamuthusamy, Machaiah Madhrira, Thomas Powell, Howard Lifland, Asha Bailey, Sarah Ashley Ford Sightler, Meera Patel Suthar, Heather Green, Samir Parikh, Isabelle Ayoub, Salem Almaani, Gabriel Contreras, Alessia Fornoni, Yelena Drexler, Abdallah Geara, Brittany Sheridan, Gaia Coppock, Jonathan Hogan, Carlos Gonzalez, Shamik Bhadra, Pradip Chowdhury, Kay Kyaw, May Tan, Lathika Raakesh, Elder Mendoza, Veronica Viramontes, Asghar Chaudhry, Juan Carbonell, Rajdeep Gadh, Victor Fernandez, Mohamad Kassem, Radu Jacob, Karen Wilder, Britt Newsome, Kathryn Klamm, Irina Suyumova, Laura Ann Kooienga, Catherine Janko, Dana Rizk, Bruce Julian, Dawn Caster, Erika Perez, Gunjan Garg, Nayan Gowda, Suneel Udani, Sreedhar Mandayam, Biruh Workeneh, Ali Assefi, Barbara Greco, Michael Germain, Jusmin Patel, Sarah Quinn, James Sullivan, Jeffrey Glaze, Phillip Madonia, Kellyn McMahon, Harold Giles, Sharon Adler, and Tiane Dai
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General Medicine - Published
- 2023
28. Temperatura e sensação térmica na depressão sertaneja: análise da região do Seridó no semiárido brasileiro
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Rebecca Luna Lucena, Raila Mariz Faria, Renata Kelly de Azevedo Lima, Tuana Raquel de Medeiros Aprígio, Alíbia Deysi Guedes da Silva, and Sara Fernandes Flor de Souza
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General Earth and Planetary Sciences ,General Environmental Science - Abstract
Pesquisas sobre sensação térmica e conforto humano em regiões naturalmente quentes como o Semiárido brasileiro são de grande importância uma vez que se referem ao bem-estar, desempenho físico, saúde humana e qualidade de vida da população. Neste sentido, a presente pesquisa se propôs a monitorar a temperatura e a sensação térmica em uma microrregião geográfica do estado do Rio Grande do Norte, o Seridó potiguar, por meio de dados meteorológicos de estações de superfície, de imagens de Satélite e através da aplicação de índices bioclimáticos voltados para o conforto térmico humano. Os dados meteorológicos foram adquiridos junto ao Instituto nacional de meteorologia - INMET. A coleta de dados da temperatura superficial foi adquirida através de imagens orbitais do Satélite Landsat 8, correspondente à faixa do infravermelho termal. Os índices de conforto térmico aplicados à área de estudo foram o Índice de Desconforto (ID) e o Índice de Temperatura Efetiva (TE). Os resultados mostraram o predomínio de altas temperaturas diárias, mensais e anuais, com médias superiores aos 26°C, ocasionando desconforto térmico na região em praticamente todos os meses do ano. Os índices bioclimáticos indicaram que a população seridoense está sujeita ao desconforto pela exposição frequente às altas temperaturas. Valores superiores aos 36°C ocorrem constantemente nos meses mais quentes do ano (setembro-novembro) em ~76,5% nos terrenos da Depressão Sertaneja do Seridó potiguar. Os resultados encontrados apontam para a importância do desenvolvimento de mais pesquisas climáticas focadas no conforto térmico humano no semiárido brasileiro, bem como de pesquisas voltadas às possibilidades de arrefecimento em áreas urbana e rurais, em especial na depressão sertaneja.
- Published
- 2021
29. Questions About Study Selection, Data Extraction, and Synthesis in the Meta-analysis Comparing Total Thyroidectomy vs Hemithyroidectomy for Treatment of Papillary Thyroid Microcarcinoma-Reply
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Vivian Hsiao, Sara Fernandes-Taylor, and David O. Francis
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Otorhinolaryngology ,Surgery - Published
- 2022
30. PERFIL CLÍNICO-EPIDEMIOLÓGICO DEL DENGUE EN EL MUNICIPIO DE ANÁPOLIS - GOIÁS DE 2016 A 2020
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Teixeira, Larissa Schults, Mota, Mariana Santos, Oliveira, Núrya Patielly Teixeira, Negreiros, Camila Beraldo, Silva, Bruna Mendonça, Correia, Sara Fernandes, and Silva, Constanza Thaise Xavier
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Dengue ,Arbovírus ,Arbovirus ,Aedes ,Epidemiology ,Epidemiologia ,Testes Sorológicos ,Epidemiología ,Serologic Tests ,Pruebas Serológicas ,Arboviruses ,General Nursing - Abstract
RESUMO Objetivo: descrever o perfil clínico epidemiológico da dengue em Anápolis, Goiás - BR entre os anos 2016 a 2020. Métodos: estudo descritivo de natureza quantitativa. Foram utilizados dados da ficha de notificação de dengue cadastrada no Departamento de Vigilância Epidemiológica. Utilizado o teste qui-quadrado com nível de significância cinco (5%) (p
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- 2022
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- View/download PDF
31. CLINICAL-EPIDEMIOLOGICAL PROFILE OF DENGUE IN THE MUNICIPALITY OF ANÁPOLIS - GOIÁS FROM 2016 TO 2020
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Larissa Schults Teixeira, Mariana Santos Mota, Núrya Patielly Teixeira Oliveira, Camila Beraldo Negreiros, Bruna Mendonça Silva, Sara Fernandes Correia, and Constanza Thaise Xavier Silva
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Dengue ,Epidemiology ,Serologic Tests ,Aedes ,Arboviruses ,General Nursing - Abstract
Objective: to describe the clinical epidemiological profile of dengue in Anápolis, Goiás - BR between the years 2016 to 2020. Methods: descriptive study of a quantitative nature. Data from the dengue notification form registered in the Epidemiological Surveillance Department were used. Chi-square test was used with significance level five (5%) (p
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- 2022
- Full Text
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32. C-Pen Exam Reader and Reading in Basic Education: Will it be a good partnership?
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Ana Ramos, Sara Fernandes, and Henrique Gil
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- 2022
33. Development of the PREMIUM Computerized Adaptive Testing for Measuring the Quality of Information Delivered to Patients with Severe Mental Illnesses
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Laurent Boyer, Sara Fernandes, Bach Xuan Tran, and Guillaume Fond
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information ,quality of life ,satisfaction ,schizophrenia ,bipolar disorders ,depression ,General Medicine - Abstract
Measuring the quality of information delivered to patients with severe mental illness (SMI), i.e., schizophrenia, bipolar disorders, and major depressive disorders, is essential to improve their quality of care. In this work, we described the different steps of the validation of the PREMIUM computerized adaptive testing (CAT) for measuring the quality of information delivered to patients with SMI. The PREMIUM item bank regarding information included 25 items. A total of 499 patients with schizophrenia (53%), bipolar disorders (26%), and major depressive disorders (22%) were recruited from numerous in- and outpatient settings in France. Unidimensionality, local independence, and monotonicity were verified for 19 items of the item bank. The psychometric properties were satisfactory for both internal (RMSEA = 0.069, CFI = 0.969, TLI = 0.963) and external validity (in particular, significant associations were found with age, educational level, and social functioning). The CAT exhibited satisfactory accuracy and precision (standard error of measurement
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- 2022
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34. Systems of Care Factors Should Be Considered in Regionalization of Congenital Cardiac Surgery
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Petros V. Anagnostopoulos, Randi S. Cartmill, Qiuyu Yang, Jessica R. Schumacher, Sara Fernandes-Taylor, Joshua L. Hermsen, and Malcolm M. DeCamp
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Pulmonary and Respiratory Medicine ,Surgery ,Cardiology and Cardiovascular Medicine - Abstract
Regionalization of care has been proposed to optimize outcomes in Congenital Cardiac Surgery (CCS). We hypothesized that hospital infrastructure/systems of care factors could also be considered in regionalization efforts.Observed-to-expected mortality (O/E ratio) and hospital volumes were obtained between 2015 and 2018 from public reporting data. Using a resource dependence framework we examined factors obtained from American Hospital Association, Children's Hospital Association and hospital websites. Linear regression models were estimated with volume only, then with hospital factors, stratified by procedural complexity. Robust regression models were re-estimated to assess the impact of outliers.We found wide variation in the volume of congenital cardiac surgeries performed (89-3,920) and in the surgical outcomes (O/E ratio range 0.3-3.1). Six outlier hospitals performed few high complexity cases with high mortality. Univariate analysis including all cases indicated that higher volume predicted lower O/E ratio (β=-0.020, SE=0.008, p=0.011). However, this effect was driven by the most complex cases. Models stratified by Society of Thoracic Surgeons-European Association for Cardio-Thoracic Surgery (STAT) category show that volume is only a significantly predictor in category 5 cases (β=-1.707, SE=0.663, p=0.012). Robust univariate regression accounting for outliers found no effect of volume on O/E ratio (β =.005, SE =.002, p=.975). Elimination of outliers through robust multivariate regression decreased the volumes/outcomes relationship and found a modest relationship between health plan ownership and outcomes.Systems of care factors should be considered in addition to volume when designing regionalization in CCS. Patient level datasets will better define these factors.
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- 2022
35. Letter to the Editor: Sensitivity of Palpation for Detection of Thyroid Nodules with Attention to Size
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Vivian Hsiao, Natalia Arroyo, Sara Fernandes-Taylor, Alexander S. Chiu, Louise Davies, and David O. Francis
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Endocrinology ,Endocrinology, Diabetes and Metabolism ,Letter to the Editor - Published
- 2022
36. O PODCAST NO ENSINO E APRENDIZAGEM DE LITERATURA NA EDUCAÇÃO BÁSICA: UM ESTUDO EM UMA ESCOLA PÚBLICA MUNICIPAL EM UBERLÂNDIA, MG, COM ÊNFASE NOS ALUNOS PROTAGONISTAS
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Sara Fernandes Teixeira Rodrigues, Anderson Claytom Ferreira Brettas, and Otaviano José Pereira
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General Medicine - Abstract
O trabalho aqui apresentado demonstra os resultados do estudo realizado sobre como o podcast pode contribuir para o ensino e aprendizagem de Literatura na educação Básica, sob os conceitos da Educação Tecnológica. Assim, neste recorte, objetivou-se demonstrar as respostas para as seguintes questões da pesquisa focadas nos alunos protagonistas participantes: Como o uso do podcast pode atuar como recurso educacional que contribua positivamente para o gosto e hábito da leitura de textos literários? O uso deste recurso tecnológico é viável à Educação Básica? Os fundamentos teóricos e metodológicos pautaram-se em Eco (1979), Lèvy (1996, 2010), Castells (2012), Nóvoa (2010) e Kenski (2004, 2015) quanto às transformações comunicacionais e tecnológicas do Século XX e as mudanças na educação e, em Freire (2012, 2013, 2015) no que se refere ao conceito educacional de podcast. A pesquisa-ação evidenciou a construção do conhecimento de forma colaborativa por meio da tecnologia educacional a partir da mediação da professora-pesquisadora, com uso do ciberespaço e influência da cibercultura. Para a produção dos dados foram utilizados como instrumentos o podcast, os produtos gerados pelos alunos protagonistas (reconto da obra literária, pod-novela, meta-podcasts e podcast de registro), questionário estruturado aplicado aos alunos beneficiados e observações da professora-pesquisadora. Constatou-se que o uso de tal ferramenta tecnológica no contexto da Educação Básica, gerou benefícios quanto ao ensino e aprendizagem de Literatura junto aos alunos protagonistas que, de modo cooperativo, confirmam que a criação do podcast contribui para fluência, gosto e hábito da leitura, aprimoramento quanto ao ato de ler e falar em público, aprofundamento dos conhecimentos voltados aos tipos textuais trabalhados (novela de cavalaria, resenha) assim como dos processos de escrita (reescrita/síntese), além do desenvolvimento da criticidade dos mesmos, poisperceberam que a pod-novela não substitui a obra, mas instiga sua leitura. Verificou-se que o podcast teve boa aceitação entre os alunos protagonistas, a ferramenta educacional apresentou certa facilidade quanto ao uso, financeiramente viável e em consonância com a Educação Tecnológica e o Ensino de Literatura na Educação Básica; no entanto, há necessidade de que o professor haja conforme o novo contexto educacional e tecnológico propõe – que gerencie habilidades e estimule a participação colaborativa de seus estudantes.
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- 2021
37. How Do Academic Otolaryngologists Decide to Implement New Procedures Into Practice?
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Cara Damico Smith, Natalia Arroyo, David O. Francis, Bethany Powers, and Sara Fernandes-Taylor
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Male ,Medical education ,medicine.medical_specialty ,Socioemotional selectivity theory ,business.industry ,Workflow ,Otolaryngology ,Practice change ,Otorhinolaryngology ,Otolaryngologists ,Humans ,Medicine ,Female ,Surgery ,business ,Referral and Consultation ,Qualitative Research - Abstract
To identify barriers and facilitators to adoption of a new surgical procedure via an implementation science framework to characterize associated socioemotional, clinical, and decision-making processes.Qualitative study with a semistructured interview approach.Large tertiary care referral center.Academic otolaryngologists with at least 2 years of practice were identified and interviewed. Transcripts were thematically coded and separated into steps in the clinical pathway. Synthesis of major themes characterized facilitators and barriers to uptake of a new surgical technique.Of 22 otolaryngologists, 19 were interviewed (85% male). They had a median 18 years of practice (interquartile range, 7.8-26.3), and 65% were subspecialty trained. In the decision to implement a new procedure, improving patient outcomes and addressing unmet clinical needs facilitated adoption, whereas costs and adopting profit-driven technologies without improved outcomes were barriers. In patient consults, establishing trust facilitated implementation of new techniques; barriers included participants' hesitation to communicate about the unknowns of a new procedure. Intraoperatively, little change to existing workflow or improved efficiency facilitated adoption, while a substantial learning curve for the new procedure was a barrier. Achieving favorable outcomes and patient satisfaction sustained implementation of new procedures. Too few referrals or indications for the new procedure hindered implementation.Our study demonstrates that innovation in otolaryngology is often an individual iterative process that providers pursue to improve patients' outcomes. Although models for the oversight of surgical innovation emphasize the need for evidence, obtaining sufficient numbers of providers and patients to generate evidence remains a challenge in specialty surgical practice.
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- 2021
38. General surgeon involvement in the care of patients designated with an American Association for the Surgery of Trauma–endorsed ICD-10-CM emergency general surgery diagnosis code in Wisconsin
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Sara Fernandes-Taylor, Jessica Schumacher, Ali Salim, Alan Smith, Chris Cribari, Dou-Yan Yang, Laura N. Godat, Marie Crandall, Angela M. Ingraham, Thomas J. Schroeppel, Ronald L. Barbosa, Kristan Staudenmayer, and Garth H. Utter
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Male ,medicine.medical_specialty ,Critical Care ,MEDLINE ,Critical Care and Intensive Care Medicine ,Article ,Global Burden of Disease ,Wisconsin ,International Classification of Diseases ,Epidemiology ,medicine ,Humans ,Medical diagnosis ,Physician's Role ,Surgeons ,business.industry ,General surgery ,ICD-10 ,Evidence-based medicine ,Middle Aged ,medicine.disease ,Appendicitis ,General Surgery ,Surgical Procedures, Operative ,Diverticular disease ,Wounds and Injuries ,Female ,Surgery ,Diagnosis code ,Emergencies ,business - Abstract
The current national burden of emergency general surgery (EGS) illnesses and the extent of surgeon involvement in the care of these patients remain largely unknown. To inform needs assessments, research, and education, we sought to: (1) translate previously developed International Classification of Diseases (ICD), 9th Revision, Clinical Modification (ICD-9-CM) diagnosis codes representing EGS conditions to ICD 10th Revision, CM (ICD-10-CM) codes and (2) determine the national burden of and assess surgeon involvement across EGS conditions.We converted ICD-9-CM codes to candidate ICD-10-CM codes using General Equivalence Mappings then iteratively refined the code list. We used National Inpatient Sample 2016 to 2017 data to develop a national estimate of the burden of EGS disease. To evaluate surgeon involvement, using Wisconsin Hospital Association discharge data (January 1, 2016 to June 30, 2018), we selected adult urgent/emergent encounters with an EGS condition as the principal diagnosis. Surgeon involvement was defined as a surgeon being either the attending provider or procedural physician.Four hundred and eighty-five ICD-9-CM codes mapped to 1,696 ICD-10-CM codes. The final list contained 985 ICD-10-CM codes. Nationally, there were 2,977,843 adult patient encounters with an ICD-10-CM EGS diagnosis. Of 94,903 EGS patients in the Wisconsin Hospital Association data set, most encounters were inpatient as compared with observation (75,878 [80.0%] vs. 19,025 [20.0%]). There were 57,780 patients (60.9%) that underwent any procedure. Among all Wisconsin EGS patients, most had no surgeon involvement (64.9% [n = 61,616]). Of the seven most common EGS diagnoses, surgeon involvement was highest for appendicitis (96.0%) and biliary tract disease (77.1%). For the other five most common conditions (skin/soft tissue infections, gastrointestinal hemorrhage, intestinal obstruction/ileus, pancreatitis, diverticular disease), surgeons were involved in roughly 20% of patient care episodes.Surgeon involvement for EGS conditions ranges from highly likely (appendicitis) to relatively unlikely (skin/soft tissue infections). The wide range in surgeon involvement underscores the importance of multidisciplinary collaboration in the care of EGS patients.Prognostic/epidemiological, Level III.
- Published
- 2021
39. ANÁLISE ECONÔMICA DA PRODUÇÃO DE LODO DE ESGOTO COMPOSTADO PARA FINS AGRÍCOLAS NA ESTAÇÃO DE TRATAMENTO DE ESGOTO DE BOTUCATU-SP
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Sara Fernandes martins, Maura Seiko Tsutsui Esperancini, N´úria Rosa Gagliardi Quintana, and Franklin De Souza Barbosa
- Abstract
ANÁLISE ECONÔMICA DA PRODUÇÃO DE LODO DE ESGOTO COMPOSTADO PARA FINS AGRÍCOLAS NA ESTAÇÃO DE TRATAMENTO DE ESGOTO DE BOTUCATU-SP. SARA FERNANDES MARTINS1, MAURA SEIKO TSUTSUI ESPERANCINI2, NURIA ROSA GAGLIARDI QUINTANA3 FRANKLIN DE SOUZA BARBOSA4 1 Departamento de Controladoria e Planejamento Integrado do Médio Tietê, SABESP, Rua Costa Leite, nº 2000, Vila Nogueira, 18606-820, Botucatu, São Paulo, Brasil, e-mail: sfmartins@sabesp.com.br 2 Departamento de Engenharia Rural e Sócio Economia, Faculdade de Ciências Agronômicas, UNESP, Av. Universitária, nº 3780, Altos do Paraíso, Botucatu - SP, 18610-034, Botucatu, São Paulo Brasil, e-mail: maura.seiko@unesp.br 3Faculdade de Botucatu – UNIBR. Avenida Paula Vieira, 624, Vila Jahu. Botucatu-SP, 18611-020, Botucatu, São Paulo Brasil, e-mail: nuria.quintana@unibrbotucatu.com.br 4 Departamento de Engenharia Rural e Sócio Economia, Faculdade de Ciências Agronômicas, UNESP, Av. Universitária, nº 3780, Altos do Paraíso, Botucatu - SP, 18610-034, Botucatu, São Paulo Brasil, e-mail: franklin.barbosa@unesp.br RESUMO: Este estudo teve como objetivo avaliar o custo de compostagem do lodo in natura produzido na Estação de Tratamento de Esgotos (ETE), da SABESP de Botucatu, São Paulo e determinar o valor dos nutrientes presentes no lodo compostado com e sem adição de material estruturante (ME). O estudo baseou-se na produção de 16 toneladas diárias de lodo, o que gera um custo anual aproximado de R$ 1.466.438,40 em transporte e disposição em aterro localizado no município de Paulínia, São Paulo. Foi estimado o custo anual de produção do lodo de esgoto compostado com e sem ME. Foram realizadas análises de amostras dos produtos finais para estimar o valor dos nutrientes presentes nos dois tipos de lodo compostado. As amostras também indicam que o produto final atende aos parâmetros da Resolução CONAMA 375/06 e às exigências do Ministério da Agricultura (MAPA). Estimou-se o valor do produto final com base nos valores médios pagos pela agricultura, verificando-se que o composto com ME geraria uma receita anual de R$ 349.653,9 e o produto sem ME de R$ 51.269,9. O resultado econômico é positivo, pois o custo da compostagem, descontado o valor dos nutrientes, é menor que o custo de disposição em aterros sanitários. Palavras-chave: lodo compostado, compostagem, tratamento de resíduos, reúso agrícola. ECONOMIC ANALYSIS OF THE PRODUCTION OF COMPOSTING SEWAGE SLUDGE FOR AGRICULTURAL PURPOSES IN THE SEWAGE TREATMENT FACILITY OF BOTUCATU-SP ABSTRACT: This study aimed to evaluate the composting cost of in natura sludge produced at the SABESP's Sewage Treatment Plant in Botucatu, São Paulo, and to determine the value of nutrients present in the composting sludge with and without the addition of structuring material (ME). The study was based on the diary production of 16 tons of sludge, which generates an approximate annual cost of R$ 1,466,438.40 in transport and disposal in a landfill located in the municipality of Paulínia, São Paulo. The annual production cost of composting sewage sludge with and without ME was estimated. Analyzes of samples of the final products were carried out to estimate the value of nutrients present in the two types of composting sludge. The samples also indicate that the final product meets the parameters of CONAMA Resolution 375/06 and the requirements of the Ministry of Agriculture (MAPA). The value of the final product was estimated based on the average amounts paid by agriculture, verifying that the compost with ME would generate an annual income of R$ 349,653.9 and the product without ME of R$ 51,269.9. The economic result is positive; that is, the cost of composting, discounted the value of the nutrients, is less than the cost of landfill disposal. Keywords: sludge composting, composting, waste treatment, agricultural reuse.
- Published
- 2021
40. Does the Portuguese economy benefit from foreign direct investment? Evidence from the presence of Spanish multinational enterprises
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Sara Fernandes Rodrigues and Faculdade de Economia
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Economia e gestão ,Economics and Business ,Economia e gestão [Ciências sociais] ,Economics and Business [Social sciences] - Published
- 2022
41. Clinical relevance of the blanking period on late recurrence after catheter ablation of atrial fibrillation
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Mariana R. Silva, Gualter S. Silva, Sara Fernandes, João Almeida, Paulo Fonseca, Marco Oliveira, Helena Gonçalves, Francisca Saraiva, António S. Barros, Pedro G. Teixeira, Ricardo L. Lopes, Francisco Sampaio, Sílvia O. Diaz, João Primo, and Ricardo Fontes‐Carvalho
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Physiology (medical) ,Cardiology and Cardiovascular Medicine - Abstract
Recurrence of atrial fibrillation (AF) within the blanking period after catheter ablation (CA) is traditionally classified as a transient and benign event. However, recent findings suggest that early recurrence (ER) is associated with late recurrence (LR), challenging the predefined "blanking period". We aimed to determine the clinical and procedural predictors of ER and LR after CA and establish the risk of LR in patients who experience ER.Retrospective single-centre study including all patients who underwent a first procedure of AF CA between 2017 and 2019. ER was defined as any recurrence of AF, atrial flutter or atrial tachycardia30 s within 90 days after CA and LR as any recurrence after 90 days of CA. A total of 399 patients were included, 37% women, median age of 58 years [49-66] and 77% had paroxysmal AF. Median follow-up was 33 months (from 13 to 61). ER after CA was present in 14% of the patients, and LR was reported in 32%. Among patients who experienced ER, 84% also had LR (p .001). Patients with ER had a higher prevalence of moderate/severe valvular heart disease, persistent AF, previous electrical cardioversion, a larger left atrium, higher coronary artery calcium score, and higher rates of intraprocedural electrical cardioversion and cardiac fibrosis on eletroanatomical mapping compared with patients without ER. After covariate adjustment, ER and female sex were defined as independent predictors of LR (hazard ratio [HR] 4.69; 95% confidence interval [CI], 2.99-7.35; p .001 and HR 2.73; 95% CI, 1.47-5.10; p = .002, respectively).The risk of LR after an index procedure of CA was significantly higher in patients with ER (five-fold increased risk). These results support the imperative need to clarify the clinical role of the blanking period.
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- 2022
42. Clinical Case 20—Recurrent intracoronary in-stent restenosis in a young woman
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Margarida Cabral, Mariana Carvalho, Sara Fernandes, Rita Carvalho, Tiago Teixeira, Catarina Ruivo, Pedro Jerónimo de Sousa, Alexandre Antunes, and João Morais
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Physiology ,Physiology (medical) ,Cardiology and Cardiovascular Medicine - Abstract
Clinical case A 39-year-old smoker woman underwent a percutaneous coronary intervention with two Zotarolimus-eluting stents implantation due to right coronary artery occlusion in the context of ST-elevation myocardial infarction (MI). She was medicated with dual antiplatelet therapy and high-intensity statin and stopped smoking. Nine months later, due to angina symptoms, cardiac catheterization with intravascular ultrasound showed severe restenosis, treated with a drug-coated balloon (DCB). Two months later, she was admitted due to non-ST elevation MI and the cardiac catheterization presented thrombotic occlusion of previously implanted stents, treated with balloon dilatation. After two months, she remained with angina and a dobutamine stress echocardiogram showed inferior wall ischemia. The angiographic revision revealed proximal in-stent restenosis, treated with DCB. About a year later, a fifth coronary angiography was performed due to recurrence of angina. Diffuse in-stent restenosis by neo-atherosclerosis was identified by optical coherence tomography. The lesion was treated with a cutting balloon and Everolimus-eluting stent implantation. The cholesterol-lowering treatment was optimized and the patient remained stable for some months. However, she is currently reporting recurrence of angina. Clinical management and guidance await Heart Team discussion. Learning points
- Published
- 2022
43. Clinical Case 06—A fatal dance: a case report of a pulmonary embolism with mobile right ventricular thrombus
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Carolina Miguel Gonçalves, Mariana Carvalho, Adriana Vazão, Sara Fernandes, Margarida Cabral, Rita Carvalho, Hélia Martins, Fátima Saraiva, and João Morais
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Physiology ,Physiology (medical) ,Cardiology and Cardiovascular Medicine - Abstract
Presentation We report a case of a 44-year-old woman with past medical history of dyslipidemia under atorvastatin, overweight and depression, that presented to the emergency department with a 1-month history of dyspnea. On physical examination, blood pressure was within normal range, however she was hypoxemic, needing oxygen via nasal cannula, and tachycardic. Pulmonary auscultation revealed basal crackles. Blood workup showed discrete leukocytosis, increased C-reactive protein, mild hypertransaminasemia and increased troponin and NT-proBNP levels. An EKG revealed sinus tachycardia with 123 beats per minute. A D-shaped left ventricle, an enlarged right ventricle and right heart mobile thrombus were observed in a transthoracic echocardiogram. Diagnosis Scoring 2 points on simplified Wells’ Score and with a visible mobile right ventricular thrombus, pulmonary embolism was suspected and further confirmed by computed tomographic pulmonary angiography. Management: In the absence of hemodynamic instability this case fulfils criteria for intermediate-high risk pulmonary embolism. Therefore, anticoagulation with enoxaparin was started under strict electrocardiographic monitoring. Unfortunately, a day later the patient had a sudden cardiac arrest in asystole, with no recuperation after prolonged advanced life support and administration of rescue thrombolysis (alteplase 50mg). Learning points
- Published
- 2022
44. Oral Presentation No. 48 Sex-based differences in patients with peripheral arterial disease admitted for acute coronary syndrome - Insights from a multicentre national registry
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Margarida Cabral, Carolina Gonçalves, Sara Fernandes, Mariana Carvalho, Catarina Ruivo, Sidarth Pernencar, Maria Fátima Loureiro, and João Morais
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Physiology ,Physiology (medical) ,Cardiology and Cardiovascular Medicine - Abstract
Atherosclerosis represents a systemic disease that can involve multiple vascular beds, including coronary artery disease and peripheral artery disease (PAD). Acute coronary syndrome (ACS) with concomitant PAD represents a high-risk subgroup that deserves special attention. In particular, sex-based differences in PAD treatment and outcomes have been discussed. This study aimed to clarify the main differences in clinical outcomes between women and men with PAD admitted for ACS. The authors performed a retrospective analysis of adult patients with PAD, included in the Portuguese Registry on Acute Coronary Syndromes (ProACS) between October 2010 and July 2022. A P-value < 0.05 is statistically significant. Of the total of 32 251 hospitalized patients admitted for ACS, 1588 (4.9%) had known PAD, of which 320 were women and 1268 men. Table 1 shows the most important baseline characteristics and differences between groups. After propensity score matching, with 640 patients, female gender appeared to be an independent factor for acute heart failure (OR 0.68, 95% CI [0.48, 0.96], P-value = 0.03) and in-hospital mortality (OR 0.36, 95% CI [0.17, 0.73], P-value < 0.01). However, there are no differences between sex for 1-year mortality (P-value = 0.70). In conclusion, in this group of patients, PAD is less prevalent among women, and probably underdiagnosed. In addition, there is a significant difference in medication with fewer women taking acetylsalicylic acid, probably undertreated. Finally, women have more in-hospital complications, including mortality. Hence, additional efforts are needed in order to better understand sex-based differences in PAD and increase awareness of this condition in women.
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- 2022
45. Poster No. 044 Cardiovascular risk factors and coronary heart disease in the young – a single centre analysis
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Carolina Miguel Gonçalves, Margarida Cabral, Mariana Carvalho, Adriana Vazão, Sara Fernandes, Rita Carvalho, Fátima Saraiva, and João Morais
- Subjects
Physiology ,Physiology (medical) ,Cardiology and Cardiovascular Medicine - Abstract
Background Cardiovascular events in the young appear to be increasing. Conversely, this is not the tendency reported in older adults. Identifying risk factors is of the uttermost importance to improve cardiovascular prevention. Material and methods Retrospective, single-centre analysis of patients with less than 45 years and suspected coronary heart disease who were subjected to cardiac catheterization in our centre during a 5-year period. Results and conclusions A total of 171 patients were included with a median age of 42 ± 6 years of which 82% were male. Overweight (73%), smoking (61%) and dyslipidemia (42%) were the most prevalent cardiovascular risk factors. Coronary heart disease was diagnosed in 67% of patients. After univariate analysis, gender (P = 0.049), age (P = 0.005), smoking (P = 0.032), low-density lipoprotein cholesterol (P = 0.005) and total cholesterol (P = 0.003) were significantly associated with disease in coronary angiography. After multivariate logistic regression, only age (OR = 1.123; CI 95% [1.036–1.217]; P < 0.005) and low-density lipoprotein cholesterol (OR = 1.016; CI 95% [1.004–1.028]; P = 0.009) remained as independent factors of coronary heart disease. It is known that awareness regarding a healthy lifestyle should be raised in the general population. As several modifiable risk factors have an impact on cardiovascular disease, there is an urgent need to improve primary prevention. Conversely, a more thorough investigation is needed in the cases where no significant coronary disease is found. According to our analysis, age and low-density lipoprotein cholesterol appear to have a stronger relevance in this young population.
- Published
- 2022
46. Poster No. 045 The role of 24-h Holter monitoring in thrombosis – a single-centre subanalysis in the young
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Carolina Miguel Gonçalves, Adriana Vazão, Mariana Carvalho, Sara Fernandes, Margarida Cabral, Rita Carvalho, Hélia Martins, Fátima Saraiva, and João Morais
- Subjects
Physiology ,Physiology (medical) ,Cardiology and Cardiovascular Medicine - Abstract
Background Undercovering the etiology responsible for pathologic states is of the uttermost importance, especially regarding young people. Arterial and venous thromboembolism may have an impact on morbidity and mortality, enhancing the need to prevent recurrences. Material and methods Retrospective, single-centre analysis of 24-h Holter monitoring in patients with thrombotic events and less than 40 years during a 5-year period, using IBM® SPSS® software to perform descriptive analysis. Results and conclusions Thrombosis was the reason for requesting 24-h Holter monitoring in 7% (n = 41) from a total of 581 exams screened – 68.3% had a stroke, 6% a transient ischemic stroke, 4.9% a pulmonary embolism, 4.9% an intestinal ischemia and 2.4% had both pulmonary embolism and deep vein thrombosis. Patients had a median age of 35 ± 6 years, 63.7% were male and past medical history consisted of cardiovascular risk factors, particularly smoking (36.6%), high blood pressure (19.5%) and dyslipidemia (12.2%). Merely 4.9% had a diagnostic finding – atrial flutter and second-degree atrioventricular block Mobitz II. On the other hand, autoimmune tests were altered in 12.2% and echocardiogram revealed patent foramen ovale, atrial septum aneurysm and interatrial septum bulging with shunt in 9.8%, 2.4% and 2.4%, respectively. Regarding management, 78% were medicated with aspirin or anticoagulant and 4.9% were submitted to percutaneous closure of patent foramen ovale. Despite low prevalence of diagnostic findings, Holter monitoring is an important complementary exam that can have therapeutic implications in these cases and, consequently, in preventing new events.
- Published
- 2022
47. Ideação suicida em médicos veterinários em Portugal, um projeto de estudo
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Magalhães, Sara Fernandes de and Rosa, Ilda Maria Neto Gomes
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Suicide ,Fatores de risco ,Risk Factors ,QIS ,Suicídio ,Ideação Suicida ,Médicos Veterinários ,Suicidal Ideation ,Veterinarians - Abstract
Dissertação de Mestrado Integrado em Medicina Veterinária, na área científica de Clínica O suicídio é a maior causa de morte entre os jovens adultos (20 a 30 anos), sendo que estudos realizados na população de Médicos Veterinários (MV) apontam um maior risco destes quer para esta problemática, quer para doenças mentais. A ideação suicida é um precedente do ato suicida, assim a determinação desta, embora não seja um método exato de determinação do risco de suicídio, é um fator predisponente para que este ocorra, indicando que o individuo que apresenta ideação suicida se entra em risco de o cometer. Vários são os estudos realizados noutros países concluíram que o risco de suicido em MV varia, consoante o estudo e país em que é realizado de 2.1 a 12 vezes superior ao da população em geral. Estudos semelhantes não podem ser realizados em Portugal dada a escassez de dados estatísticos e às falhas na categorização da profissão, uma vez que os MV tanto podem ser classificados como trabalhadores de saúde, tratadores de animais; profissionais qualificados da produção animal. Dada esta impossibilidade, a avaliação da presença de ideação suicida pode ser um bom indicador para avaliar se à semelhança de outros países os MV em Portugal também se encontram em maior risco de incidência de ideação suicida, uma vez que já foi relatada que esta pode ser 5.5 vezes superior à da população em geral. A incidência de outras patologias mentais tais como, depressão maior, burnout, ansiedade, fadiga de compaixão, que são também fatores de risco para o suicídio foram também apontadas como sendo particularmente altas nesta área. A presença de ideação suicida seria identificada através da aplicação do Questionário de ideação suicida (QIS), assim como um questionário sociodemográfico. A avaliação dos fatores de riscos ou protetores da presença de ideação suicida podem ser avaliados através de entrevista guiadas ou através de questionários aplicados à posteriori. Assim o objetivo é a criação de uma ferramenta que permita detetar se em Portugal os MV são afetados pela presença de ideação suicida, quais os fatores de risco próprios desta população e quais as medidas preventivas que podem ser tomadas para diminuir a incidência da ideação suicida, se se determinar que à semelhança dos colegas de outros países esta é uma realidade que também afeta os MV em Portugal ABSTRACT - Suicidal Ideation in Veterinarians in Portugal, a study Project - Suicide is the leading cause of death among young adults (20 to 30 year old) , and the studies conducted in Veterinarians indicate ever a greater risk for suicide and for mental illness. The suicide ideation is a precedent of suicidal act, so the determination of this, although not exact, can determinate a bigger risk of suicide. Several studies carried out in other countries have concluded that the risk of suicide in Veterinarians varies, depending on the study and country in which it is carried out, from 2.1 to 12 times higher than that of the general population. Similar studies cannot be carried out in Portugal due to the lack of statistical data and the flaws in the categorization of the profession, since this can be classified as health workers, animal handlers, qualified professionals in animal production. The presence of suicidal ideation would be identified through the application of the Suicidal Ideation Questionnaire (SQ), as well as a sociodemographic questionnaire. The assessment of risk or protective factors for the presence of suicidal ideation can be assessed through guided interviews or through questionnaires applied to posteriority. The objective of this project is to create a tool that allows detecting the presence of suicidal ideation, which are the risk factors typical of this population and what preventive measures can be taken to reduce the incidence of suicidal ideation, if it is determined that, like colleagues from other countries, this is a reality that also affects Veterinarians in Portugal N/A
- Published
- 2022
48. Early humoral response to COVID-19 vaccination in patients living with obesity and diabetes in France. The COVPOP OBEDIAB study with results from the ANRS0001S COV-POPART cohort
- Author
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Bénédicte Gaborit, Sara Fernandes, Paul Loubet, Laetitia Ninove, Anne Dutour, Bertrand Cariou, Muriel Coupaye, Karine Clement, Sébastien Czernichow, Claire Carette, Noémie Resseguier, Laure Esterle, Sabrina Kali, Marie Houssays, Xavier de Lamballerie, Linda Wittkop, Odile Launay, and Martine Laville
- Subjects
Endocrinology ,Endocrinology, Diabetes and Metabolism - Published
- 2023
49. INTEGRATED ANALYSIS OF GEODIVERSITY IN THE MUNICIPALITY OF ACARI-RN, BRAZILIAN SEMIARID REGION
- Author
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Erik Leandro Viana de Sales, Daví Do Vale Lopes, Sara Fernandes de Souza, and João Santiago Reis
- Abstract
Commonly geodiversity is associated with geological knowledge, leaving aside others abioticcomponents such as geomorphological, pedological and hydrological. Geodiversity, compared tobiodiversity, does not yet have the same prestige and political position. In the Brazilian semiaridregion, there are still many gaps related to the knowledge of geodiversity. In 2022, the SeridóGlobal Geopark was recognized by UNESCO as a territory that provides an intriguing insight intothe Earth’s history through its unique natural landscape, cultural and culinary history. Among themunicipalities inserted in the territory of the Seridó Geopark is Acari-RN, which has richgeodiversity. The objective of this work was to present an integrated analysis of the geodiversityof the municipality of Acarí-RN, encompassing information related to variety of geological,geomorphological, pedological and hydrological features and processes. Fieldwork was carriedout, we identified and mapped landforms and their physiognomic aspects and georeferenced usingportable GPS. We collected soils to represent the different landforms. A ten geosites werecharacterized in the municipality, four of them belonging to the Seridó Geopark, in which we alsosought to consider the information about the relief and soils. In the present work, the term"integrated analysis of geodiversity" was used in order to encourage debate and to make it clearthat geodiversity is not limited to geological aspects. The integrated analysis of geodiversity canbe a subsidy for geotourism, regional valorization of the semiarid and also preservation of theCaatinga biome. The identification and characterization of potential geosites in Acarí-RN canhelp for developing efficient municipal policy to combining the conservation of their uniquegeological heritage with public outreach and sustainable development
- Published
- 2022
50. Calibration and Validation of a PREMIUM-DT Item Bank to Measure the Experience of Drug Therapy for Patients with Severe Mental Illness
- Author
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Sara, Fernandes, Laurent, Boyer, Xavier, Zendjidjian, Anderson, Loundou, Jeremie, Riedberger, Pierre-Michel, Llorca, Pascal, Auquier, Guillaume, Fond, and Collaborators Of The French Premium Group
- Subjects
General Medicine ,psychiatry ,mental health ,schizophrenia ,depressive disorders ,bipolar disorders ,patient-reported experience measures ,health services research - Abstract
The aim of this study was to (1) calibrate an item bank to measure patients’ experience of drug therapy for adult patients with SMIs and (2) develop computerized adaptive testing (CAT) to improve its use in routine practice. This is a cross-sectional, multicentric study involving 541 patients with schizophrenia, bipolar disorder, and major depressive disorder. Analyses based on classical test and item response theories were performed. After 7 highly inter-correlated items and 4 items with low factor loadings were removed, the remaining 26 items were sufficiently unidimensional (RMSEA = 0.069, CFI = 0.969, TLI = 0.963) and showed adequate fit to the generalized partial credit model. There was no differential item functioning by gender, age, care setting, or diagnosis from moderate- to large-magnitude. The mean score was 46.0 ± 16.9 and was significantly higher for patients reporting good medication adherence. The resulting PREMIUM-DT item bank has strong psychometric properties, and CAT facilitates widespread use in clinical settings (an average of 8 items administered, corresponding to a reliability of >0.90). Our results suggest that practical information and information about the side effects of psychotropic treatments and how to cope with them should be targeted as a priority to improve patients’ experience of drug therapy.
- Published
- 2022
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