2,530 results on '"Sancar A"'
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2. Learning from expert or own practice: reflectively editing video cases for professional development
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Raziye Sancar, Deniz Atal, Eğitim Fakültesi, and Raziye Sancar / 0000-0002-2875-9233
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Philosophy ,Teacher education ,video editing ,video cases ,preservice teachers ,professional development - Abstract
This research aimed to investigate how the video editing process professionally affected preservice teachers' reflection levels and whether it differed by the type of in-class teaching experiences (their own and expert teacher experiences). The editing procedure of video cases means selecting and combining parts from an entire recorded in-class teaching experience and adding reflective thinking on actions. Seven participants took part in the research process during a semester, with three-cycle of the video case editing procedures being applied separately to two different research groups. Both inductive and deductive content analysis procedures were applied in a total of 21 video cases edited by PTs. By editing in-class teaching experiences, PTs could deeply analyse the events and transform their reflections on the contextual features. The process facilitated PTs' professional development by identifying, noticing, and reflecting on in-class teaching experiences. PTs learned to analyse their experiences by using different types of perspectives. PTs could deeply analyse the events and transform their reflections on the contextual features. Contrary to the difficulties for PTs' reflection-in-action, the process of editing in-class teaching experiences expanded their reflection-on-action opportunities.
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- 2022
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3. The effect of the clinical pharmacist in minimizing <scp>drug‐related</scp> problems and related costs in the intensive care unit in Turkey: A non‐randomized controlled study
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Yunus Emre Ayhan, Sait Karakurt, Mesut Sancar, and AYHAN Y. E. , KARAKURT S., SANCAR M.
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Turkey ,Drug-Related Side Effects and Adverse Reactions ,PCNE ,IMPACT ,Farmakoloji ,Life Sciences (LIFE) ,Pharmacy ,Pharmacists ,Sağlık Bilimleri ,intensive care unit ,THERAPY ,drug-related problems ,EVENTS ,Drug Guides ,Yaşam Bilimleri ,Health Sciences ,FARMAKOLOJİ VE ECZACILIK ,Humans ,Farmakoloji, Toksikoloji ve Eczacılık (çeşitli) ,Pharmacology (medical) ,Prospective Studies ,General Pharmacology, Toxicology and Pharmaceutics ,cost saving ,Eczacılık ,PHARMACOLOGY & PHARMACY ,Pharmacology, Toxicology and Pharmaceutics (miscellaneous) ,Pharmacology ,PHARMACOLOGY & TOXICOLOGY ,Temel Bilimler ,Basic Pharmaceutics Sciences ,Life Sciences ,ROUNDS ,Pharmacology and Therapeutics ,Genel Farmakoloji, Toksikoloji ve Eczacılık ,clinical pharmacist ,Farmakoloji (tıbbi) ,Intensive Care Units ,Temel Eczacılık Bilimleri ,İlaç Rehberleri ,Yaşam Bilimleri (LIFE) ,Farmakoloji ve Toksikoloji ,Pharmacy Service, Hospital ,Natural Sciences ,INTERVENTIONS - Abstract
What is known and objective:Drug-related problems (DRPs) are common inhospitalized patients in intensive care unit (ICU). The aim of the study is to reduceDRPs and associated costs with clinical pharmacist's (CP) recommendations.Methods:The study is a prospective, non-randomized controlled study conducted inthe ICU for a total of 6 months (1 January 2021–30 June 2021) in 2-month con-trol, 2-month study, and 2-month control periods. Patients who were hospitalizedfor more than 24 h and used more than one medication were included in thestudy. The PCNE V9.1 Classification system was used in the classification ofDRPs. During the intervention period, CP recommendations for DRPs wereproposed to the healthcare team.Results and discussion:A total of 146 patients were included in the study. A total of1061 DRPs from all periods were detected. The most common causes of DRPs werepotential drug–drug interactions (31.76%), high dose (12.44%), and dose timinginstruction errors (9.24%). For 347 DRPs identified during the study period, 259 inter-ventions (74.63%) were recommended, and 238 (91.89%) were accepted by physi-cians. Interventions were mostly made as interrupting/discontinuing the drug(28.02%), changing the dose (25.27%), changing the instructions for use (20.32%),and starting a new drug (15.93%). Cost savings were achieved with CP recommenda-tions applied.What is new and conclusion:The CP's recommendations were highly accepted bythe healthcare team. With the CP's participation in routine patient rounds in thehealthcare team of the ICU, drug-related costs would also decrease.
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- 2022
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4. Production of hydrophilic silicone softener with antibacterial properties and evaluation of its performance on fabrics
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Burcu Sancar Beşen, Pınar Parlakyiğit, Leyla Eren Karahan, Cumhur Kirilmiş, and Sakine Erdoğan
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Polymers and Plastics ,Materials Science (miscellaneous) ,General Agricultural and Biological Sciences ,Industrial and Manufacturing Engineering - Published
- 2023
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5. COVID-19 TANILI HASTALARDA TABURCULUK KRİTERİ DEĞİŞİKLİĞİNİN TEDAVİ SONUCU VE MALİYETE ETKİSİ
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Zeynep TÜRE, Merve SANCAR YETİKCAN, Gamze KALIN ÜNÜVAR, Fatma CEVAHİR, Orhan YILDIZ, and Bilgehan AYGEN
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General Earth and Planetary Sciences ,General Environmental Science - Abstract
Haziran 2020 tarihinde normalleşme sürecine geçilmesi ile koronavirüs hastalığı-2019 (COVID-19) tedavisi tamamlanan hastaların tedavi sonrası polimeraz zincir reaksiyonu testi negatifliği beklenmeden taburcu edilmesi kararı alınmıştır. Bu çalışmada uygulama öncesi ve uygulama sonrası birer aylık periyotlardaki hasta profili, hastanede yatış süresi ve maliyetin karşılaştırılması planlandı. 15 Haziran 2020 öncesi (birinci grup) ve sonrası (ikinci grup) birer aylık süreçlerde pandemi servisinde COVID-19 olası ve kesin tanısı ile takip edilen hastaların demografik verileri, ko-morbiditeleri, laboratuvar bulguları, tedavi, prognoz ve tedavi maliyetleri karşılaştırıldı. Çalışmaya birinci gruptan 46, ikinci gruptan 49 olmak üzere toplam 95 hasta dâhil edildi. Birinci grupta kesin vaka oranı %37 iken bu oran ikinci grupta %59’du (p=0.040).Kesin vaka tanımına uyan hastalarda birinci grubun hastanede yatış süresi ortancası ikinci gruba göre daha uzundu (Grup 1 için;10 (3-21), Grup 2 için; 6 (3-12) gün, p=0.003). İkinci gruptaki hastalarda COVID-19 ile uyumlu tipik tomografi bulgu oranı daha yüksekti (Grup 2 için %52 ve Grup 1 için%26, p=0.018). İlk grupta hidroksiklorokin ile tedavi oranı ikinci gruba göre daha yüksek iken (Grup 1 için %72 ve Grup 2 için %41, p=0.004) ikinci grupta favipiravir ile tedavi oranı daha fazla idi (Grup 2 için %55 ve Grup 1 için %17, p=0.001). Birinci grupta tedavi maliyeti ortancası 2798 (661-45465) TürkLirası(TL), ikinci grupta ise 1627 (748-4496) TL idi (p=0.001). COVID-19 tanılı hastaların tedavi sonrası izolasyon sürelerini hastane dışında tamamlaması hastane maliyetinin azaltılması açısından anlamlıdır.
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- 2023
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6. Text classification-based petition recognition and routing system: a Turkish case study
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Yasin Sancar, Işıl Karabey Aksakallı, and Tevhit Karacalı
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Computational Theory and Mathematics ,Artificial Intelligence ,Computer Networks and Communications ,Applied Mathematics ,Electrical and Electronic Engineering ,Computer Science Applications ,Information Systems - Published
- 2023
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7. Investigation of the effects of some pile yarn parameters on crucial properties of towels
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Navruz Üdürgücü, Burcu Sancar Beşen, and Seda Şerafettinoğlu
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Polymers and Plastics ,Materials Science (miscellaneous) ,General Agricultural and Biological Sciences ,Industrial and Manufacturing Engineering - Published
- 2023
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8. Development and evaluation of a turkish scale to assess medication literacy for adults
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Ozgenur TORUN, İlkay MEMİÇ, Pınar AY, Mesut SANCAR, Aysu SELCUK, Ecehan BALTA, Vildan OZCAN, Betul OKUYAN, and Torun O., Memiç İ., Ay P., Sancar M., Selcuk A., Balta E., Ozcan V., Okuyan B.
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Pharmaceutical Science ,Molecular Medicine ,Original Article - Abstract
OBJECTIVES: This study aimed to develop a Turkish scale to assess medication literacy and to evaluate its psychometric properties among adults having at least 12 years of education in Türkiye. MATERIALS AND METHODS: After the composition of a preliminary set of items, the content validity of the scale was assessed by an e-Delphi process and a pilot study. The psychometric properties of the scale were evaluated in 358 participants, who had above 12 years of education: university students, academics and, administrative staff from two faculties (pharmacy and law) in two universities located in two major cities (İstanbul and Ankara) in Türkiye between March and May, 2021. The test-retest validity was assessed by Spearman’s rho and Wilcoxon test. Internal consistency was evaluated by Kuder Richardson 20. Principal component analysis was conducted. RESULTS: The last version of the medication literacy scale consisted of 8 items. There was a positive correlation (Spearman’s rho: 0.570; p
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- 2023
9. Cyber identity: determining the meaning-making process of university students in terms of the phenomenological perspective
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Raziye SANCAR
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Communication ,Education - Published
- 2023
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10. The Use of Direct Oral Anticoagulants in Atrial Fibrilation and Related Risk Groups: A Traditional Review
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Yunus Emre AYHAN, Duygu ÜNDER, Enes Emir İLERLER, İpek MİDİ, and Mesut SANCAR
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General Medicine - Published
- 2023
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11. Investigation of Medications Without Pediatric Dosage Forms Used in General Pediatric Service: A Descriptive Study
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Yunus Emre AYHAN, Cüneyd ENVER, Betül OKUYAN, Perran BORAN, and Mesut SANCAR
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Pediatrics, Perinatology and Child Health - Published
- 2023
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12. Comparison of the Frequency of Fibromyalgia Syndrome Between Those with and Without Obstructive Sleep Apnea Syndrome
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Mehmet OKÇU, Figen TUNCAY, Arzu ERTÜRK, and Samet Sancar KAYA
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Physiology (medical) ,Rehabilitation - Published
- 2023
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13. Lateral Atlantoaxial Osteoarthitis Accompanied with Large Subchondral Cysts: A Case Report of Incidental Finding on CBCT
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Bilay STEVANOVIC SANCAR, Rümeysa ŞENDİŞÇİ, and Sevcihan GÜNEN YILMAZ
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Pharmacology (medical) - Published
- 2023
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14. Nurses' Knowledge and Practice of Nasogastric Tube Placement: A Descriptive Research Study
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Behire Sancar, Yagmur Surmeli, Ayse Buket Dogan, and Fugen Ozcanarslan
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Advanced and Specialized Nursing ,Gastroenterology - Published
- 2023
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15. Investigation of Urinary Findings in Urticaria Patients
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Didem Mullaaziz, Serap Maden, and Nuriye Sancar
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- 2023
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16. Psychometric properties of the theory-based clinical behavioral intention scale among Turkish community pharmacists
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Betul OKUYAN, Vildan OZCAN, Pinar AY, Ozge DURAK ALBAYRAK, Meltem TURKER, Nazlican UCAR, Zeynep SAYIN, and Mesut SANCAR
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- 2023
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17. THE EFFECT OF PERSONALITY CHARACTERISTICS OF HEALTHCARE WORKERS ON THEIR PERCEPTIONS OF ORGANIZATIONAL SUPPORT AND ORGANIZATIONAL TRUST
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Tekin SANCAR and Fuat YALMAN
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General Engineering - Abstract
Aim: The main purpose of this study is to determine the effect of the personality characteristics of healthcare workers on their perceptions of organizational support and organizational trust. Method: The population of the research consisted of the employees of the private hospital providing secondary care in three different regions in Istanbul. The convenience sampling method was preferred in the study. The data were collected using the online questionnaire technique. The total number of questionnaires that were evaluated and used in the data analysis is 510. SPSS 23 and AMOS 26 package programs were used to analyze the data. Descriptive statistics, multiple linear regression analysis, and structural equation modeling were applied to the data. Findings: The findings obtained with the structural equation analysis showed that the construct validity of the model was provided. The direct causal effect of the personality traits of health workers on their perceptions of organizational support is positive, and the effect level is 0.122; On the other hand, it has been determined that the direct causal effect on organizational trust perceptions is positive, and the effect level is 0.225. Results: According to the results obtained from the regression analysis, it is seen that the high level of extraversion, responsibility, and openness characteristics of health workers positively affected their perceptions of organizational support. Therefore, healthcare professionals who are more extrovert, adaptable, and responsible show higher organizational support and organizational trust. It is suggested that personality traits being compatible with the organization may have a positive effect on outputs such as employee performance, job satisfaction, commitment, and motivation, and the study should be expanded in this direction.
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- 2022
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18. Age-related Comparison of Hip Joint Morphology in Isolated Femur Neck Fractures
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Saygin Kamacı, Sancar Bakırcıoğlu, Ömür Çaglar, Bülent Atilla, and A. Mazhar Tokgözoğlu
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General Medicine - Abstract
Objective: Femoral neck fractures mostly occurs due to high-energy trauma in young population and management differs compared to elderly. Different geometric parameters in the hip joint can play a role in fracture morphology regarding to the age. Present study aims to compare hip morphology between young and elderly population Materials and methods: 45 patients with isolated femoral neck fracture included to the study. Patients were divided into two regarding to the age; group 1 (younger than 60 yr.) and group 2 (older than 60 yr.). Garden and Pauwels classifications, Sharp angle (acetabular index-AI), acetabular depth (AD), Hip-axis length (HLA), Neck-shaft angle (NSA), Center-edge angle (CE), Singh indexes and femur head extrusion indexes were compared between groups. Results: The mean age of group 1 (22 patients) was 48 ± 10.4 while the mean age of group 2 (23 patients) was 77 ± 6.3. Significant differences found in 3 parameters; the mean HLA (13.4 ± 1.4 cm vs 12 ± 1.1 cm) (p: 0,034), the Sharp angle (37.9° ± 5° vs 40.3° ± 3°) (p: 0.047) and the CE (38.1° ± 6.2° vs 34.8° ± 4.5°) (p: 0.48) between group 1 and 2 respectively. No statistically significant difference was found in terms of AD, NSA, Singh index and extrusion index. Conclusions: Our study shows influence of proximal femoral and acetabular morphology on femoral neck fracture in young patients and may help future studies to reveal the relevance between hip morphology and fractures type.
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- 2022
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19. Professional Identity Development During Video Cases Discussions: Does It Make a Difference Whether Teacher Candidates Focus Their Own Videos or Experts’ Videos?
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Raziye SANCAR and Deniz Atal
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Education and Educational Research ,Eğitim, Eğitim Araştırmaları ,General Medicine ,Professional development ,Professional identity ,Teacher candidates ,Video cases discussion - Abstract
This research aimed to investigate dimensions of professional identity that have been reflected in the different video-case discussions of teacher candidates and explore the differences between own and expert video case discussions. In this qualitative case study, data were obtained from eight teacher candidates through online video case discussions implemented in three cycles among two separate groups. In the discussion platform, while one group focus on their own videos, the other group focus on expert teachers’ video. As a result, professional identity indicators, gathered under three themes, named task-based, profession-based, and self-interpretation-based indicators, were reflected in the discussions. Moreover, it is noteworthy differences between the own video-case discussion group and expert video-case discussion group in ‘profession-based and ‘self-interpretation-based’ dimensions of professional identity. Results suggest that especially discussing own video-cases can be a productive tool that helps the teacher candidates to make stronger theory-practice connections and feel like ‘a professional teacher’.
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- 2022
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20. Identification of Drug-Related Problems and Investigation of Related Factors in Patients with COVID-19: An Observational Study
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Muhammed Yunus BEKTAY, Mesut SANCAR, Fatmanur KARAKÖSE OKYALTIRIK, Bülent DURDU, Fikret Vehbi İZZETTİN, BEKTAY, MUHAMMED YUNUS, OKYALTIRIK, FATMANUR, DURDU, BÜLENT, and İZZETTİN, FIKRET VEHBI
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PHARMACOLOGY & TOXICOLOGY ,General Engineering ,Life Sciences (LIFE) ,Life Sciences ,Sağlık Bilimleri ,Pharmacology and Therapeutics ,Clinical Medicine (MED) ,Yaşam Bilimleri (LIFE) ,Health Sciences ,Farmakoloji ve Toksikoloji ,Yaşam Bilimleri ,Klinik Tıp (MED) ,Farmakoloji, Toksikoloji ve Eczacılık (çeşitli) ,Eczacılık ,Pharmacology, Toxicology and Pharmaceutics (miscellaneous) - Published
- 2022
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21. The diagnostic role of 'acceleration time' measurement in patients with classical low flow low gradient aortic stenosis with reduced left ventricular ejection fraction
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Kadriye Memic Sancar, Gamze Babur Guler, Halil Ibrahim Tanboga, Aysel Turkvatan Cansever, Ali Riza Demir, Arda Guler, Meltem Tekin, Begum Uygur, Ali Birant, Yalcin Avci, Ekrem Guler, and Mehmet Erturk
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In our study, we aimed to assess the role of acceleration time (AT), ejection time (ET), and AT/ET ratio to distinguish between true and pseudo severe AS in patients with classical low flow-low gradient (LF-LG) aortic stenosis (AS) with reduced left ventricular ejection fraction (LVEF).Sixty-seven classical LF-LG AS with reduced LVEF patients who underwent dobutamine stress echocardiography (DSE) were included in the study. According to DSE results, all patients were divided into two groups; true AS and pseudo severe AS. Aortic valve calcium score was measured in patients with inconclusive DSE results. AT and other ejection dynamics (ET and AT/ET) were calculated by taking baseline echocardiographic records into account for all patients. The predictive power of AT and other ejection dynamics were evaluated to estimate true and pseudo severe AS.According to DSE results, out of 67 patients, 44 (65.7%) was diagnosed as true severe AS. There was a statistically significant relation between baseline AT and true AS [adjusted OR 4.47 (95% CI 1.93-10.4), p = 0.001]. The best cutoff value of AT was measured as 100 msec according to the Youden index. This value had a sensitivity value of 77%, specificity value of 87%, positive predictive value of 92%, and a negative predictive value of 67%.The measurement of AT can predict the DSE outcome and can be used for diagnostic purposes to distinguish between true and pseudo severe AS in classical LF-LG AS patients with reduced LVEF.
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- 2022
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22. Investigation of tie-rod connection types on stone masonry arches
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Fırat, Fatih Kürşat, Sancar Kayabaşı, Mehtap, and Mühendislik Fakültesi
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Finite Element Analysis ,Architecture ,Tie-rods ,Arches ,Building and Construction ,Historical Buildings ,Masonry ,Safety, Risk, Reliability and Quality ,Civil and Structural Engineering - Abstract
Tie-rods fixed in different ways in arch and column (pillar) junction areas of historical structures are frequently encountered. These tension members used to sustain the stability of arches play a significant role in the survival of the whole building. In this study, the effect of different tie-rod systems that are fixed on stone arches on the overall behavior of arch is investigated. In the scope of this study, seven stone arches, one reference with no tie-rod, and six repaired using different tie-rod systems were tested under vertical loading. Tested specimens were also analyzed numerically using a commercial computer program called LUSAS. The data obtained as a result of the experiments and the outputs obtained from the numerical models were compared with each other. The main aim of this research is to examine the efficiency, viability, and practicality of replacement techniques recommended for tie-rods in historic masonry stone arches. At the end of the study, the difficulties in the application of tie-rod systems in restoration and strengthening works are examined and the most suitable tie-rod system is revealed by drawing attention to mistakes made during restoration works.
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- 2022
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23. Impact of a clinical pharmacist-led stewardship program for the appropriate use of acid suppression therapy in older hospitalized patients: a non-randomized controlled study
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Hatice Ikra Dumlu, Mesut Sancar, Ali Ozdemir, Betul Okuyan, and Dumlu H. I., Sancar M., Ozdemir A., Okuyan B.
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Medication review ,IMPROVE ,Life Sciences (LIFE) ,Pharmaceutical Science ,Inappropriate Prescribing ,Pharmacy ,Proton pump inhibitor ,Pharmacists ,Toxicology ,DISEASE ,Medication Reconciliation ,PROTON PUMP INHIBITORS ,FARMAKOLOJİ VE ECZACILIK ,Humans ,Pharmacology (medical) ,PHARMACOLOGY & PHARMACY ,Aged ,Retrospective Studies ,Pharmacology ,PHARMACOLOGY & TOXICOLOGY ,Yaşam Bilimleri (LIFE) ,Farmakoloji ve Toksikoloji ,STRESS-ULCER PROPHYLAXIS ,Potentially inappropriate medication ,Pharmacy Service, Hospital ,Geriatric - Abstract
The potentially inappropriate use of the proton pump inhibitors is prevalent in older adults.To evaluate the impact of a clinical pharmacist-led stewardship program for the appropriate use of acid suppression therapy in older hospitalized patients.This parallel nonrandomized controlled study was conducted at an internal medicine service of a tertiary training and research hospital between September 2019 and August 2021. Older patients (≥ 65 years old and received proton pump inhibitors within 48 h of admission) were allocated to two groups according to their number of medical file records, whether odd or even, two groups: control and clinical pharmacist-led stewardship program for the appropriate use of acid suppression therapy (including medication reconciliation and medication review) during the hospital stay. Primary outcome measures were the rate of appropriate use of proton pump inhibitors during hospitalization and potentially inappropriate proton pump inhibitor use at discharge.The rate of appropriate proton pump inhibitor use during hospitalization was significantly higher in the clinical pharmacist-led program (n = 100) than in the control group (n = 97) (46.4% vs. 79.0%; P 0.001). The rate of potentially inappropriate proton pump inhibitor use at discharge was significantly lower (61.7% vs. 35.1%; P 0.05) in the clinical pharmacist-led program among the older patients discharged with a proton pump inhibitor prescription.A clinical pharmacist-led stewardship program for the appropriate use of acid suppression therapy improved the rate of appropriate proton pump inhibitor use and reduced the potentially inappropriate proton pump inhibitor use during the hospital stay.NCT05113667 (17 October 2021-registered retrospectively).
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- 2022
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24. Reliability of High-Alert Medications Questionnaire in Turkish Healthcare Professionals
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Feyza Öztürk, Betül Okuyan, Mesut Sancar, Muhammed Yunus Bektay, Öznur Özkan, Beyza Torun, Ozturk F., Altiparmak O., Torun B., Bektay M. Y., SANCAR M., OKUYAN B., and BEKTAY, MUHAMMED YUNUS
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knowledge ,Medicine (General) ,PRESCRIPTION ,Turkish ,high-risk medication ,pharmacist ,Medicine (miscellaneous) ,Sağlık Bilimleri ,Fundamental Medical Sciences ,Clinical Medicine (MED) ,TIP, GENEL & DAHİLİ ,immune system diseases ,Klinik Tıp (MED) ,MEDICINE, GENERAL & INTERNAL ,Reliability (statistics) ,eczacı ,INSTRUMENT ,Klinik Tıp ,healthcare professional ,General Engineering ,food and beverages ,virus diseases ,General Medicine ,NURSES KNOWLEDGE ,medication safety ,Tıp ,ilaç güvenliği ,General Health Professions ,language ,population characteristics ,Medicine ,Tıp (çeşitli) ,Medical emergency ,Family Practice ,education ,Temel Tıp Bilimleri ,nurse ,sağlık çalışanları ,Assessment and Diagnosis ,Temel Bilgi ve Beceriler ,Genel Tıp ,Pathophysiology ,hemşire ,R5-920 ,Health Sciences ,Internal Medicine ,medicine ,Aile Sağlığı ,Ozturk F., Altiparmak O., Torun B., Bektay M. Y. , SANCAR M., OKUYAN B., -Reliability of High-Alert Medications Questionnaire in Turkish Healthcare Professionals-, BEZMIALEM SCIENCE, cilt.10, sa.1, ss.17-23, 2022 ,Dahiliye ,Patofizyoloji ,Health professionals ,business.industry ,Fundamentals and Skills ,CLINICAL MEDICINE ,medicine.disease ,Değerlendirme ve Teşhis ,language.human_language ,Yüksek riskli ilaçlar ,bilgi seviyesi ,business ,Genel Sağlık Meslekleri - Abstract
Objective: This study aimed to evaluate the reliability of the HighAlert Medications (HAM) Questionnaire in Turkish healthcare professionals. Methods: This methodological study was conducted between December 2017 and January 2018 in a private university hospital. The healthcare professionals, including nurses, health service technicians, and pharmacists, who are older than 18 years old were eligible for this study. After following the appropriate translation and cultural adaptation process, the internal consistency of the HAM Questionnaire using the Kuder-Richardson 20 coefficient and test-retest reliability was evaluated. Results: Among 146 healthcare professionals, the mean age was 25.40±5.16 years, wherein 76% were females. Most participants were nurses (69.9%) and other healthcare professionals were health service technicians (28.1%) and pharmacists (2.0%). The mean total score of the HAM Questionnaire was 70.00±19.50. The KuderRichardson 20 was 0.815. A statistically significant correlation was found between the scores of the HAM Questionnaire at baseline and after 15 days, which confirmed the test-retest reliability (r=0.527; p
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- 2022
25. Türkiye'de Yetişen Fumaria asepala Boiss. ve Fumaria schleicheri Soy.-Will. microcarpa Boiss. ex Hausskn. için Taksonomik Bir Çalışma: Morfolojik, Anatomik ve Palinolojik Çalışmalardan Elde Edilen Kanıtlarla
- Author
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Pelin YILMAZ SANCAR
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General Medicine - Abstract
Fumaria L. cinsi Papaveraceae familyasına ait bir cins olup, morfolojik olarak ayırt edilmeleri oldukça güç bitkilerden oluşur. Bu çalışmada, Fumaria cinsine ait iki türün yapısal özelliklerini ortaya çıkarılması amaçlanmaktadır. Bu amaçla yaprak, sepal, petal boyutları ve şekilleri, filament ve anter uzunlukları ile çeşitli morfolojik özellikleri incelenmiş ve gerekli ölçümler alınmıştır. Anatomik çalışmalar kapsamında, türlerin kök ve gövdelerinden elle enine kesitler alınmış ve zıt boyama tekniği kullanılarak hazırlanan preparatlar, ışık mikroskobu altında fotoğraflanarak anatomik özellikleri belirlenmiştir. Ek olarak polen özelliklerini ortaya çıkarmak için ışık mikroskobu ve SEM çalışmaları yapılmıştır. Yapılan çalışmalardan elde edilen sonuçlara göre Fumaria asepala Boiss. ve Fumaria schleicheri Soy.-Will. subsp. microcarpa Boiss. ex Hausskn. türleri bulunduğu bölgede yan yana yaşayarak ilginç bir özellik sergilemektedir. Morfolojik olarak birbirine çok benzeyen bu iki tür yapılan mikroskobik çalışmalar sonucu F. asepala da sepallerin bulunmayışı özelliği ile F. schleicheri subsp. microcarpa ’dan ayrılmaktadır. Yine meyve mikromorfolojileri de türlerin ayrımında değerli veriler sunmaktadır. Anatomik çalışmalardan elde edilen sonuçlar ise her iki türde de benzer bulunmuştur. Palinolojik çalışmalarda incelen polenlerin, polen tipi her iki tür için de suboblate olduğu, polenlerin apertürleri Pantoporate/Porat olduğu gözlenmiştir. Apertür sayısı F. asepala’da 6-7, F. schleicheri subsp. microcarpa ’da 4-8 iken, apertür çapı F. asepala’da daha büyük ölçülmüştür. Ayrıca F. schleicheri subsp. microcarpa ’nın polenleri F. asepala’ya göre daha büyük olarak ölçülmüştür. Elde edilen bu sonuçlar kombine edilerek türlerle ilgili orijinal veriler elde edilmiş, cinse ait temel sistematik veriler literatüre kazandırılmıştır. Bu çalışma Elazığ ilinde yetişen bazı Fumaria türleri ile ilgili yapılan detaylı bir sistematik çalışma olması açısından önem taşımaktadır.
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- 2022
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26. Management of Aberrant Left Hepatic Artery During Laparoscopic Gastrectomy and Consequences
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Musluh Hakseven, Özhan Çetindağ, Gökhan Avşar, Rıza Deryol, Şeref Dokçu, Serdar Culcu, Serkan Akbulut, Sancar Bayar, Ali Ekrem Ünal, and Salim Demirci
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Hepatic Artery ,Liver ,Gastrectomy ,Stomach Neoplasms ,Humans ,Lymph Node Excision ,Laparoscopy ,Surgery ,Retrospective Studies - Published
- 2022
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27. Effects of delayed breast reconstruction on the thoracolumbar vertebrae in patients undergoing unilateral mastectomy: A retrospective cohort study
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Savaş Serel, Necip Sefa Özden, Yasemin Aydınlı, Zehra Akkaya, Çağlar Uzun, and Sancar Bayar
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Lumbar Vertebrae ,Spinal Fusion ,Treatment Outcome ,Mammaplasty ,Quality of Life ,Humans ,Pain ,Breast Neoplasms ,Female ,Surgery ,Mastectomy ,Retrospective Studies - Abstract
Post-mastectomy changes vertebral column alignment. There is limited data assessing spine curvature after breast reconstruction. In this study, the effects of delayed breast reconstruction on the Cobb angle and quality of life indicator (Oswestry disability index [ODI]) were evaluated in patients undergoing unilateral mastectomy.This study was performed as a retrospective review of 40 patients who had delayed reconstruction for breast cancer at a single center between 2015 and 2018. Patients completed a standardized questionnaire, the ODI, at the beginning and 12 months after the operation. The Cobb angles of the vertebral columns and spinal curve directions were determined using posteroanterior chest radiographs obtained pre- and postoperatively.Mean age and body mass index (BMI) were 49.9 ± 9 years and 30.1 kg/mBreast reconstruction positively affects vertebral alignment and leads to better posture, physical function and decreased back pain in breast cancer survivors, significantly improving their quality of life.
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- 2022
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28. The impact of clinical pharmacist-led hypertension screening at the community pharmacy in Türkiye
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Ceren E. DEMİRCİOGLU AKYILMAZ, Betul OKUYAN, Mesut SANCAR, and Demircioglu Akyilmaz C. E. , OKUYAN B., SANCAR M.
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PHARMACOLOGY & TOXICOLOGY ,Temel Bilimler ,Basic Pharmaceutics Sciences ,screening ,Life Sciences ,Life Sciences (LIFE) ,Sağlık Bilimleri ,Pharmacology and Therapeutics ,Genel Farmakoloji, Toksikoloji ve Eczacılık ,clinical pharmacist ,Farmakoloji (tıbbi) ,Temel Eczacılık Bilimleri ,Yaşam Bilimleri (LIFE) ,preventive health ,Yaşam Bilimleri ,Health Sciences ,Farmakoloji ve Toksikoloji ,Hypertension ,FARMAKOLOJİ VE ECZACILIK ,community pharmacy ,Pharmacology (medical) ,General Pharmacology, Toxicology and Pharmaceutics ,Natural Sciences ,Eczacılık ,PHARMACOLOGY & PHARMACY - Abstract
© 2022 Marmara University Press.The aim of this study was to evaluate the impact of clinical pharmacist-led hypertension screening program (including referring high-risk individuals who are not aware of being hypertensive or prehypertensive to the physician) at a community pharmacy in Türkiye. This prospective observational pilot study was conducted in a community pharmacy located in Mersin-Türkiye between October 2017 and April 2018. Blood pressure measurements were performed by the clinical pharmacist at baseline and follow-up. The rate of participants who had high blood pressure measurements (≥140 mmHg for systolic and/or ≥90 mmHg for diastolic) was determined at the baseline by clinical pharmacist. According to the guidelines, participants with high blood pressure were referred directly to the physician by the clinical pharmacist. In the follow-up, the number of patients diagnosed with prehypertension or hypertension and the changes in their measurement of blood pressure were identified between baseline and follow-up. According to findings of clinical pharmacist-led blood pressure measurement, 23 (37.1%) out of 62 participants with high blood pressure were referred to the physician by the clinical pharmacist. In the follow-up, it was determined that 12 patients (52.2%) out of 23 participants were diagnosed with hypertension by a physician and eight patients (34.8%) out of 23 participants had prehypertensive. According to the findings of this pilot study, it was determined a positive impact of the clinical pharmacist-led hypertension screening program for high-risk individuals for hypertension.
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- 2022
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29. Factors associated with Turkish pharmacists’ intention to receive COVID-19 vaccine: an observational study
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Muhammed Yasir Demirci, Pinar Ay, Muhammed Yunus Bektay, Mesut Sancar, Betül Okuyan, Okuyan, Betul, Bektay, Muhammed Yunus, Demirci, Muhammed Yasir, Ay, Pinar, Sancar, Mesut, and BEKTAY, MUHAMMED YUNUS
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Male ,medicine.medical_specialty ,COVID-19 Vaccines ,Turkey ,Turkish ,Pharmaceutical Science ,Pharmacy ,Intention ,DETERMINANTS ,Pharmacists ,Toxicology ,Logistic regression ,Pandemic ,Humans ,Medicine ,Health belief model ,KNOWLEDGE ,Pharmacology (medical) ,ATTITUDES ,Pandemics ,Vaccine hesitancy ,Pharmacology ,PANDEMIC INFLUENZA A/H1N1 ,SARS-CoV-2 ,business.industry ,BELIEF MODEL ,Vaccination ,Transtheoretical model ,COVID-19 ,EMERGENCY ,language.human_language ,Cross-Sectional Studies ,Family medicine ,language ,Observational study ,HEALTH-CARE WORKERS ,business ,BEHAVIOR ,Research Article - Abstract
Background Pharmacists have been taking part in vaccination services during the COVID-19 pandemic. However, research identifying pharmacists’ intention to get COVID-19 vaccine is limited. Aim The objective of this study was to determine the intention to receive COVID-19 vaccine and to identify the factors related to it based on the Health Belief Model framework among Turkish pharmacists. Method This is an observational study conducted between December 2020 and January 2021. The online survey was sent to all hospital and community pharmacists working in Turkey. Transtheoretical Model of Behaviour Change and Health Belief Model were used for the development of the questionnaire. Univariate and multivariate logistic regression analyses were conducted to identify factors associated with the intention to receive COVID-19 vaccine. Results Among all participants (n = 961), 74.7% had an intention to receive the COVID-19 vaccine. In model 1, perceived susceptibility, perceived severity, perceived benefits, and perceived barriers were associated with their intention to receive the COVID-19 vaccine (p
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- 2021
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30. Investigation of drug-related problems in patients hospitalized in chest disease wards: A randomized controlled trial
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Muhammed Yunus Bektay, Mesut Sancar, Fatmanur Okyaltirik, Bulent Durdu, Fikret Vehbi Izzettin, and BEKTAY M. Y., SANCAR M., OKYALTIRIK F., DURDU B., İZZETTİN F. V.
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Pharmacology ,PHARMACOLOGY & TOXICOLOGY ,Temel Bilimler ,Basic Pharmaceutics Sciences ,Farmakoloji ,pharmaceutical care ,Life Sciences ,Life Sciences (LIFE) ,chest diseases ,Sağlık Bilimleri ,Pharmacology and Therapeutics ,clinical pharmacist ,drug-related problems ,Farmakoloji (tıbbi) ,Temel Eczacılık Bilimleri ,Yaşam Bilimleri (LIFE) ,cognitive pharmacy services ,Yaşam Bilimleri ,Health Sciences ,Farmakoloji ve Toksikoloji ,FARMAKOLOJİ VE ECZACILIK ,Pharmacology (medical) ,Natural Sciences ,Eczacılık ,PHARMACOLOGY & PHARMACY - Abstract
Objective: According to the World Health Organization (WHO), chest diseases are among the 10 diseases that cause the highest mortality worldwide. Drug-related problems (DRPs), readmission, and antimicrobial resistance are critical problems in chest disease wards. Active involvement of clinical pharmacists (CPs) who are focused on reducing the risks of potential problems is needed. The aim of this study is to investigate the effects of pharmaceutical care (PC) services on the pulmonology service.Method: A randomized controlled trial at a university hospital in Istanbul was conducted between June 2020 and December 2021. The participants were randomized into the control group (CG) and intervention group (IG). In the CG, CPs identified and classified the DRPs according to Pharmaceutical Care Network Europe v9.0 (PCNE) and provided solutions to DRPs for the IG. The effect of PC services was evaluated by the number and classification of DRPs, and readmissions within 30 days were compared between the two groups.Results: Out of 168 patients, 82 were assigned to the IG. The average number of medicines administered per patient in the CG and IG was 14.45 ± 7.59 and 15.5 ± 6.18, respectively. In the CG and IG, the numbers of patients with DRPs were 62 and 46, respectively. The total number of DRPs was 160 for CG and 76 for IG. A statistically significant difference was found in favor of the IG, in terms of the number of patients with DRPs, the total number of DRPs, and readmission within 30 days (p < 0.05).Conclusion: In this study, CP recommendations were highly accepted by the healthcare team. Pharmaceutical care services provided by CPs would decrease possible DRPs and led to positive therapeutic outcomes. Cognitive clinical pharmacy services have beneficial effects on health care, and these services should be expanded in all settings where patients and pharmacists are present.
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- 2023
31. AKDENİZ HEMŞİRELİK SEMPOZYUMU TAM METİN
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Sancar, Behire, Caner, Muhdedir, Eren, Nadiye Barış, ÖZCANARSLAN, Neslihan, Doğan, Aysel, Durna, İlknur, Kara, Bircan, and Gezer, Derya
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Enfeksiyon ,Diyabetik ayak - Abstract
uscehder. org.tr 2 SAAT 08:00/ 09:00 Kayıt 09:00/ 09:30 Açılış, Saygı Duruşu ve Protokol Konuşmaları Muhdedir Caner (USCEHDER Başkanı) Bilge Aydınoğlu Gökşen (Mersin Şehir EAH. Sağlık Bakım Hizmetleri Müdürü) Bahar Aydınlı (Mersin Şehir EAH. Başhekimi) Emrah Ceviz (Mersin İl Sağlık Müdürü Tensip Buyurursa) 09:30/ 10:00 Konferans: 1 Konferans Başkanı: Doç. Dr. Bahar Aydınlı- Hem. Bilge Aydınoğlu Gökşen Sağlık Hizmeti İlişkili Enfeksiyonlar ve Maliyet: Hem. Muhdedir Caner 10:00/ 11:00 Oturum1: Oturum Başkanı: Prof. Dr. Fügen Özcanarslan Sağlık hizmeti ilişkili enfeksiyonlar ve el hijyeni: Dr. Öğr. Üyesi Behire Sancar Cerrahi alan enfeksiyonları: Dr. Öğr. Üyesi Aysel Doğan Sağlık bakım ilişkili enfeksiyonlar ve kontrol demetleri: Uzm. Hem. Esra Peker 11:00/ 11:30 Çay Kahve Arası 11:30/ 12:30 Oturum 2: Oturum Başkanı: Doç. Dr. Gülay Altun Uğraş Güvenli Cerrahinin Kullanılanılmasının Önemi: Dr. Öğr. Üyesi Ahmet Karaman Güvenli Cerrahinin Kullanılanılmasındaki Engeller: Öğr. Gör. Dr. Seher Gürdil Yılmaz 12:30/ 13:00 Öğle Yemeği 13:00/ 13:30 Konferans: 2 Konferans Başkanı: Hem. Muhdedir Caner Sağlık Hizmetlerinde Enfeksiyon Kontrolünde Yeni Teknolojiler: Arş. Mesut Ergün 13:30/ 14:30 Oturum 3: Oturum Başkanı: Doç. Dr. Duygu Sönmez Düzkaya Basınç Yaraları: Değerlendirme ve Yönetimi: Dr. Öğr. Üyesi Derya Gezer Diyabetik Ayak Yarası: Önleme ve Bakım: Dr. Öğr. Üyesi Nadiye Barış Eren Hastane Kaynaklı İYE Önlemede Kanıta Dayalı Uygulamalar: Öğr. Gör. Büşra Gök 14:30/ 15:00 Oturum 4: Oturum Başkanı: Dr. Öğr. Üyesi Neslihan Özcanarslan Sağlık çalışanlarının hukuki sorumlulukları: Öğr. Gör. Dr. Bircan Kara Sağlık çalışanlarının periyodik sağlık kontrolleri: Öğr. Gör. Pelin Zıvdır Yeşilyurt 15:00/ 15:30 Çay Kahve Arası 15:30/16:30 Oturum 5: Oturum Başkanı: Öğr. Gör. Dr. Bircan Kara Ameliyathanede ekip iş birliği ve iletişim: Uzm. Zeynep Koç Ameliyathane ve MSÜ’lerde atık yönetimi: Hemşire İlknur Durna Ameliyathanede sağlık çalışanlarının maruz kaldığı tehlike ve riskler: Dr. Öğr. Üyesi Neslihan Özcanarslan 16:30/ 17:00 Değerlendirme Kapanış uscehder. org.tr 3 KATKI VERENLER Prof. Dr. Fügen Özcanarslan Doç. Dr. Bahar Aydınlı Doç. Dr. Duygu Sönmez Düzkaya Doç. Dr. Gülay Altun UğraĢ Hem. Bilge Aydınoğlu GökĢen ĠÇĠNDEKĠLER Sağlık Hizmeti İlişkili Enfeksiyonlar ve Maliyet 4/7 Sağlık hizmeti ilişkili enfeksiyonlar ve el hijyeni 8/14 Cerrahi alan enfeksiyonları 15/17 Sağlık bakım ilişkili enfeksiyonlar ve kontrol demetleri 18/24 Güvenli Cerrahinin Kullanılanılmasının Önemi 25/29 Güvenli Cerrahinin Kullanılanılmasındaki Engeller 30/35 Basınç Yaraları : Değerlendirme ve Yönetimi 36/41 Diyabetik Ayak Yarası : Önleme ve Bakım 42/48 Hastane Kaynaklı İYE Önlemede Kanıta Dayalı Uygulamalar 49/57 Sağlık çalışanlarının hukuki sorumlulukları 58/66 Sağlık çalışanlarının periyodik sağlık kontrolleri 67/71 Ameliyathanede ekip iş birliği ve iletişim 72/77 Ameliyathane ve MSÜ’lerde atık yönetimi 78/88 Ameliyathanede sağlık çalışanlarının maruz kaldığı tehlike ve riskler 89/97 Sempozyum kitabının tüm yayın hakları Uluslararası Sterilizasyon CerrahiHemĢireleri, Enfeksiyon HemĢireleri Dernegine aittir. Kitabın hiçbir bölümü yazılı izin olmaksızın basılamaz, fotokopi, kayıt, tekrar çoğaltma gibi elektronik ve mekanik bir Ģekilde çoğaltılamaz. Kitabdaki bölümleren ve içeriklerinden yazarlar sorumludur. uscehder. org.tr 4 Hastane Enfeksiyonlarında Maliyet Analizi Muhdedir Caner Kırıkkale Yüksek Ġhtisas Hastanesi 5356203471muktedircaner@yahoo.com Sağlık Hizmeti ĠliĢkili Enfeksiyonlar(SBĠĠ), hasta hastaneye yattığında inkübasyon döneminde olmayan ve hastanede kazanılan enfeksiyonlardır. Enfeksiyonun türüne göre değiĢmekle birlikte sıklıkla hastaneye yattıktan 48-72 saat sonra ve taburculuğu takiben ilk 10 gün içinde ortaya çıkar. Hasta morbidite ve mortalitesinde artıĢa neden olur. Her yıl dünya üzerinde milyonlarca kiĢi SBĠĠ"den etkilenmekte ve SBĠĠ tüm dünyada sağlık hizmeti sunumunda en sık görülen komplikasyon olarak ortaya çıkmaktadır. Hastanede yatan hastaların yaklasık %5"inde sağlık hizmeti iliĢkili enfeksiyonlar gelismektedir. Hastane enfeksiyonu, günümüzde gelismis ve gelismekte olan ülkelerde, yüksek morbidite ve mortalite nedeni olması ve olusturdugu ekonomik sonuçlar nedeniyle önemli bir halk sağlığı sorunudur. ABD'de yılda hastaneye yatan 35 milyon kadar hastanın 1,75-3,5 milyonunda (%5-10) SBĠĠ geliĢtiği, Avrupa'da çeĢitli hastanelerde % 6-9 arasında değiĢen sıklıkta görüldüğü bildirilmektedir. Bazı yayınlarda bu sıklık %15'lere çıkmaktadır. Farklı ülkelerde yapılan çalıĢmalarda, hastaneye yatan hastalarda %3,1-14,1 arasında değiĢen sıklıkta SBĠĠ geliĢtiği bildirilmektedir. Dünya Sağlık Örgütü (DSÖ), geliĢmekte olan ülkelerde hijyenik koĢulların yetersizliği, SBĠĠ ve enfeksiyon kontrolünün yeterince önemsenmemesi nedeniyle geliĢmiĢ ülkelere kıyasla sorunun daha büyük boyutlarda olduğunu belirtmektedir. DSÖ verilerine göre; geliĢmiĢ ülkelerde 19952008 yılları arasında yapılan çalıĢmalarda, yatan hastaların %5-12"sinde en az bir SBĠĠ geliĢtiği tespit edilmiĢ olup, en sık neden üriner sistem enfeksiyonları olarak belirlenmiĢtir. Yoğun bakım ünitelerinde yatan hastalarda %51"e varan sıklıkta enfeksiyon görüldüğü ve bu enfeksiyonların çoğunluğunun da SBĠĠ olduğu bildirilmiĢtir. Cerrahi alan enfeksiyonu sıklığı, cerrahi giriĢim baĢına %2-3 olarak saptanmıĢtır. Türkiye"de Ulusal Hastane Enfeksiyonları Sürveyans Ağı (UHESA) tarafından sürdürülen çalıĢmalara iliĢkin sonuçlar henüz yeni elde edilmeye baĢlanmıĢtır. ġubat 2011"de yayınlanan 20062010 Türkiye Hastane Enfeksiyonları Sürveyansı Ön Raporu"na göre Türkiye"de Santral Venöz Katater ĠliĢkili Kan DolaĢımı Enfeksiyonları (SVKĠKDĠ) hızı 2008 yılında %5,61; 2009 yılında %5,01; Üriner Katater ĠliĢkili Üriner Sistem Enfeksiyonları (ÜKĠÜSĠ) hızı 2008 yılında %5,18; 2009 yılında %4,39; Ventilatör ĠliĢkili Pnomoni (VĠP) hızı ise 2008 yılında %17,14; 2009 yılında %15,37 olarak bildirilmiĢtir (9). Mali Analiz-Neden? Sağlık Hizmeti ĠliĢkili Enfeksiyonların maliyet analizinde, sadece „direkt hastane maliyetlerinin içindeki „ölçülebilir maliyetler" değerlendirmeye alınmakta, sosyal ve hukuki kayıplar değerlendirmeye alınmamakta, kayıpların yalnızca bir kısmını ölçülmekte, bilinenin çok üzerinde çok fazla kayıp olduğu bilinmektedir. Dünya Sağlık Örgütü verilerine göre, geliĢmiĢ ülkelerde %7 oranında hastane enfeksiyonu görülmekte olup, geliĢmemiĢ ülkelerde kayıt sistemi yeterli olmamakla birlikte %10 hastane enfeksiyonu görüldüğü belirtilmiĢtir Her 100 hastaneye kabul için yaklaĢık 4,5 hastane enfeksiyonu görülen Amerika BirleĢik Devletleri"nde, 1.7 milyon insan hastane enfeksiyonlarından etkilenmekte, buna bağlı 99000 ölüm gerçekleĢmektedir. uscehder. org.tr 5 Ġngiltere"de yıllık 100.000 H geliĢtiği ve bunların 5000"inin öldüğü ve 930 milyon pound ek maliyete neden olduğu hesaplanmıĢtır. Pamukkale Üniversitesi Tıp Fakültesi"nin 200 yataklı 11 yataklı yoğun bakım ünitesi bulunan Egitim ve Arastırma Hastanesi"nde 227 hastanın dahil edildiği 102 hastada SHĠE geliĢmiĢ, 125 kontrol grubunda SHĠE geliĢmemiĢtir. SHĠE geliĢme oranı %44,93 dür. Enfeksiyonun geliĢmesi; kuruma Yatak ücretlerinde 2 kat, Laboratuar giderlerinde 1,5 kat, Antibiyotik giderlerinde 12 kat, Hastalara kullanılan diğer medikal ilaç giderlerinde 3,5 kat Tedavi hizmeti giderlerinde ortalama 3 kat ek mali yük getirdiği görülmüĢtür. ABD"de, Sağlık Hizmeti ĠliĢkili Enfeksiyonların yıllık maliyeti 28.4-33.8 milyar dolardırSağlık Hizmeti ĠliĢkili Enfeksiyonların yaklaĢık % 20"si kolay önlenebilir enfeksiyonlar olup, önlendiğinde 5.7- 6.8 milyar dolar maliyette azalma olacağı belirtilmiĢtir. Sağlık hizmeti iliĢkili enfeksiyonların %70"i önlendiğinde ise 25-31.5 milyar dolar daha düĢük maliyet olacağı bildirilmiĢtir. Avrupa ülkelerinde %7.1 görülen hastane enfeksiyonları, 4 milyon hastayı 4.5 milyon epizotla etkilemekte, yıllık yaklaĢık 16 milyon gün ekstra yatıĢ gününe neden olmakta, buna bağlı olarak 37000 ölüm gerçekleĢmektedir. Avrupa"da direkt tedavi maliyetleri yıllık 7 milyar Euro olarak bildirilmiĢtir. ÇalıĢma Ülke Ek maliyet (Dolar) 1974 (Westwood) ABD 1650 1980 (Haley) ABD 1018 1993 (Diaz-Molina) Ġspanya 1909 1993 (Coello) Ġngiltere 1759 1997 (Yalçın) Türkiye 1582 1997 (Leroyer)* Fransa 10440 1998 (Orrett) Trinidad 1910 1998 (Andersen) Norveç 2200 1999 (Navarette)* Meksika 11682 2001 (Plowman) Ġngiltere 4500 uscehder. org.tr 6 2005 (Chen) Tayvan 3306 (Hastane enfeksiyonlarının neden olduğu ek maliyet) Moleküler tiplendirme laboratuvarını içeren yoğun bir enfeksiyon kontrol programı uygulamasının gerçekleĢtirildiği bir çalıĢmada HĠ oranı %23 oranında (%3.3-2.6) düĢürülmüĢ, hastanede yatıĢ süresi ortalama 2.2 gün azaltılabilmiĢtir. Ġki yıllık bir süreç içerisinde yılda ortalama 270 Hastaneenfeksiyonu olgusunun oluĢumu engellenmiĢ ve yaklaĢık 4.368.100 Dolar kazanç sağlanmıĢtır. Ülkemizde Hacettepe Üniversitesi Tıp Fakültesi Hastanesi'nde Sağlık Hizmeti ĠliĢkili Enfeksiyonlar nedeniyle hastaların hastanede kalıĢ süresinin hasta baĢına yaklaĢık 20 gün uzadığı ve hasta baĢına maliyetin 1582 Dolar arttığı gösterilmiĢtir. Ülkemizde yapılan baĢka bir çalıĢmada; GATA"da 2008 yılında yapılan çalıĢmada, Sağlık Hizmeti ĠliĢkili Enfeksiyonlar nedeniyle yatıĢ süresinin ortalama 16.1 gün arttığı, mortalitenin %14.5 daha fazla görüldüğü belirlemiĢ, hasta baĢına 5544TL (4435 dolar) ek maliyet olduğu tespit edilmiĢtir. Sağlık Hizmeti ĠliĢkili Enfeksiyonlu hastaların günlük olarak 104.3TL ek harcamaya neden olduğu ilaç maliyet artıĢının %84'ünün kullanılan ilave antibiyotiklerden kaynaklandığı belirlenmiĢtir Sağlık hizmeti iliĢkili enfeksiyonlar; Zamanın boĢa geçmesi, Kayıp maaĢlar, hastanın gelir kaybı, ĠĢ verimliliğinde azalma, Hasta yakınlarının gelir kaybı, Hastanın arkadaĢları ve yakınlarının kayıpları (ziyaret masrafları, yol, yemek ve konaklama masrafları vs.) neden olmaktadır. Her sağlık hizmeti iliĢkili enfeksiyonun, önlenebilir tıbbi hata olduğu unutulmamalıdır. Örnek Simülasyon hastasına sosyal güvenlik kurumunun ödediği 37778TL, Hastaneye maliyeti 50498TL olarak gerçekleĢmiĢtir. Simülasyon Hastane Enfeksiyonlarına Bağlı Kayıp/Maliyet Direk Hastane Maliyetleri Sabit Masraflar Bina masrafları (elektrik, su, yatak vs.) Hastanede kullanılan araçlar Teknolojik cihazlar Otelcilik hizmetleri (çamaşır, temizlik vs) Ölçülebilen Masraflar Yemek İlaçlar Tedavi Testler (mikrobiyolojik, biyokimyasal patolojik, radyolojik) İşlemler Konsultasyonlar İndirekt Maliyetler Kayıp maaşlar, hastanın gelir kaybı Iş verimliliğinde azalma Hasta yakınlarının gelir kaybı Zamanın boşa geçmesi Hastanın arkadaşları ve yakınlarının kayıpları (ziyaret masrafları, yol, yemek ve konaklama masrafları vs.) Yasal boyut uscehder. org.tr 7 (Caner M, Özgün Ç) Sağlık bakımı iliĢkili enfeksiyonlar, morbidite ve mortaliteye neden olmalarının yanında ciddi mali kayıplara da yol açmakta, bu enfeksiyonların önlenmesi ile, hasta sağlığının düzelmesinin yanında ülke ekonomisine de katkıda bulunulacaktır Kaynaklar 1. Jarvis WR. Selectedaspects of thesocioeconomicimpact of nosocomialinfections: Morbidity, mortality, costandprevention. Infect Control HospEpidemiol1996;17:552-57 2. AĢçıoğlu,S. Hastane Enfeksiyonları. Türk Hij.Den. Biyol. Derg. 2007; 64:1-3 3. Herwaldt,L.A.,Wenzel,R.P. Dynamics of hospital-acquiredinfection, Washington: "Murray, PR, Baron EJ, Pfafler, MA, Tenover FC, Yolken RH (eds): Manual of ClinicalMicrobiology, 2..baskı" s.:169, 1995. 4. SayıĢtay BaĢkanlığı, Hastane Enfeksiyonları ile Mücadele. Performans Denetim raporu, Ankara; 2007. 5. DSÖ. Theburden of healthcareassociatedinfectionworldwide.(2011) EriĢim: (http://www.who.int/gpsc/ country_work/burden_hcai/en/index.html). EriĢim tarihi: 01.04.2011 6. Ertek,M., Müezzinoğlu,Ġ.A., Kurtoğlu,D., ve ark. Türkiye Hastane Enfeksiyonları Sürveyansı Ön Rapor 2006-2010. Ankara: Refik Saydam Hıfzıssıhha Merkezi BaĢkanlığı Ulusal Hastane Enfeksiyonları Sürveyans Ve Kontrol Birimi, 2011. 7. YaelWaknineHospitalInfectionsCostBillions, StudyShows, Medscape, September 03, 2013 8. Plowmann R, Graves N, Griffin MAS, etal. The rate and cost of hospital-acquiredinfections occuring in patients admitted toselected specialities of a district generalhospital in England and the nationalburden imposed. J Hosp Infect2001;47:198-209 9. Scott II RD Thedirectmedicalcost of Health-CareAssociationInfection U.S HospitalsandBenefits Of Prevention 2009 10. Yalçın NA, Hayran M, Ünal S. Hastane infeksiyonlarınınfarmakoekonomik yönden incelenmesi: Hacettepe deneyimi. Hastane Ġnfeksiyonları Dergisi 1997;1:46-9 11. https://www.researchgate.net/publication/264901062_Hastane_infeksiyonlarinda_maliyet_analizi- 12. Haley RW. Cost-benefitanalysis of infectioncontrolprograms. In: Bennett JV, Brachman PS (eds). HospitalInfections. 4th ed. Philadelphia: Lippincott-RavenPublishers, 1998:249-67. 13. Özbek G. Bir Eğitim Hastanesinde Hastane Enfeksiyonlarının Maliyet Analizi Enfeksiyon Hastalıkları Ve Klinik Mikrobiyoloji Anabilim Dalı Hastane Enfeksiyonları Yüksek Lisans Tezi, 2008 14. Harran Üniversitesi Tıp Fakültesi Dergisi 2008;5(1):15-21 uscehder. org.tr 8 SAĞLIK HĠZMETĠ ĠLĠġKĠLĠ ENFEKSĠYONLAR VE EL HĠJYENĠ Dr. Öğr. Üyesi Behire SANÇAR, , Toros Üniversitesi Sağlık Bilimleri Fakültesi 05052520273, behire.sancar@toros.edu.tr ORCID ID: 0000-0003-1053-6688 GiriĢ Doğrudan veya dolaylı olarak sağlık hizmeti ile iliĢkili olarak geliĢen “Sağlık Hizmeti ĠliĢkili Enfeksiyonlar” (SHĠE), eski adıyla hastane enfeksiyonları (nozokomiyalenf.)sağlık kurumuna baĢvuru esnasında belirti ve bulguları olmayan ve kuluçka döneminde de olmayan hastalarda, hastaneye yatıĢtan 3 gün (72 saat) ve sonrasında ortaya çıkan veya taburcu olduktan 10 gün sonrasına kadar geliĢen enfeksiyonlardır. Ancak bu tanım cerrahi enfeksiyonlarda, prosedüre bağlı olarak 30–90 gün içinde geliĢen enfeksiyonları da kapsamaktadır. SHĠE; Endojen (hastanın kendi florası kaynaklı) ve eksojen (hasta bakımında görev alan sağlık personeli, tıbbi cihazlar kaynaklı) olabilir. Ayrıca ilgili sağlık kuruluĢundaki sağlık çalıĢanlarında meslekleriyle iliĢkili olarak geliĢen enfeksiyonlar da SHĠE kategorisinde ele alınır. Sağlık Hizmeti ĠliĢkili Enfeksiyonlar"ın Önemi Ġnsidansı, mortalite ve morbiditenin en yaygın nedenleri arasında olması, yaĢam kalitesi üzerine etkisi, maliyeti, antibiyotik direnci geliĢimine katkısı ve getirdiği ek sağlık hizmeti yükünün yanı sıra sağlık hizmetlerine toplumun güvenini olumsuz etkilemesi ve hukuksal boyutu ile de SHĠE"ler önemli bir halk sağlığı sorunudur. ECDC (EuropeanCentersforDisease Control andPrevention)'den alınan bir rapora göre, SHĠE"lar sadece doğrudan maliyetler olmak üzere yılda yaklaĢık 7 milyar €'dur. Dört Avrupa ülkesinde yapılan yakın tarihli bir çalıĢmada, kateter iliĢkili kan dolaĢımı enfeksiyonu atağı baĢına hastanede ek kalma süresi 4 ila 14 gün arasında değiĢmiĢtir. Sağlık Hizmeti ĠliĢkili EnfeksiyonlarKüresel Bir Sorundur Birçok yüksek gelirli ülkede, ulusal ve bölgesel sağlık otoriteleri özel sağlık kurumları ile birlikte önleme, kontrol, gözetim ve raporlama tedbirlerini yürürlüğe koymaktadırlar. SHĠE insidansı, son yıllarda önemli ölçüde azalmıĢ olsa da, özellikle risk altındaki nüfus arasında yüksek kalmaya devam etmektedir. Özellikle düĢük ve orta gelirli ülkelerde, zorluklar, az geliĢmiĢ altyapı ve hijyen ve sağlık sorunları ile daha da karmaĢık bir hal almıĢtır. Dünya uscehder. org.tr 9 Sağlık Örgütü (DSÖ), yoğun bakım servislerinde edinilen enfeksiyonun yüksek gelirli ülkelerdekinden en az 2-3 kat daha fazla olduğunu ve cihaz/alet ile bağlantılı enfeksiyonun ABD"dekine göre 13 kat kadar daha fazla olabileceğini öngörmektedirler. Antimikrobiyal dirençli organizmaların ortaya çıkması, SHĠE"ın yayılmasına ve Ģiddetinin artmasına neden olmaktadır. SHĠE salgınını deneyimleyen bir Sağlık Kurumu, ciddi hasta bakım zorlukları, maliyet yükü ve imajı ve itibarı üzerinde potansiyel negatif etkiyle karĢı karĢıya kalmaktadır.En sık görülen dirençli mikroorganizmalar hastane florasına ve bölümlere göre değiĢmekle birlikte; E-Coli, Klebsiellapneumoniaeve diğer enterik gram negatif bakteriler, Pseudomonasaeruginosa ve MRSA, VRE ve Kandidacinsi maya mantarlardır. Sağlık Hizmeti ĠliĢkili Enfeksiyonlar"ın Kapsamı Hastanelerde SHĠE açısından baĢta yoğun bakım üniteleri (YBÜ) olmak üzere, onkoloji, yeni doğan ve cerrahi servisler yüksek riskli baĢlıca alanlardır. Bu alanlar ayrıca enfeksiyon kontrol önlemlerinin en zor uygulanabildiği alanlardır. Günümüzde hastane enfeksiyonları kavramından “sağlık hizmeti iliĢkili enfeksiyon” tanımına geçilmesiyle ağız ve diĢ sağlığı merkezleri, hemodiyaliz merkezleri, günübirlik cerrahiler gibi ayaktan verilen sağlık hizmetleri, yaĢlı bakım evlerinde verilen sağlık hizmetleri ve evde sağlık hizmetleri de kapsanmaktadır. Sağlık Hizmeti ĠliĢkili Enfeksiyonlar"ın Epidemiyolojisi ABD ve Avrupa'da üriner sistem enfeksiyonu hastane genelinde (sırasıyla %36 ve %27) en sık görülen enfeksiyondur. ABD'de bunu cerrahi alan enfeksiyonu (%20), kan dolaĢımı enfeksiyonu ve pnömoni (her ikisi de %11) izlemektedir. Avrupa'da ikinci en sık görülen tip, alt solunum yolu enfeksiyonunu (%24), cerrahi alan enfeksiyonu (%17) ve kan dolaĢımı (%10,5) enfeksiyonudur. Ülkemizde SHĠE hızı %1 ile %16,5 arasındadır. Yoğun bakım
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32. Türkiye’de Organik Tarım (Bitkisel Üretim)
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Bulut, Sancar
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Türkiye’de ilk resmi organik tarım hareketi 1992yılında Ekolojik Tarım Organizasyonu Derneği’nin kurulmasıyla başlamıştır. Dahasonra, organik tarımla ilgili faaliyetler 2003 yılından itibaren Gıda Tarım veHayvancılık Bakanlığı Bitkisel Üretim Genel Müdürlüğü bünyesinde mevzuatı ilebirlikte yürütülmektedir. Organik tarımsal faaliyetler 2004 yılında yürürlüğegiren 5262 sayılı “Organik Tarım Kanunu” ve 2006 yılından beri yürürlükte olan “Organik Tarımın Esasları ve Uygulanmasınaİlişkin Yönetmelik” hükümleri çerçevesinde yürütülmektedir. Ayrıca, 18.08.2010tarih ve 27676 sayılı “Organik Tarımının Esasları ve Uygulamasına İlişkinYönetmelik” hükümlerince Organik Tarım Geçiş Süreci de organik tarıma dâhiledilmektedir. Her aşaması kontrollü ve sertifikalandırılan bir sistem olanorganik tarım AB organik tarım mevzuatına uyum sağlayarak uluslararasıstandartlarda yürütülmektedir. 2021 yılı verileri doğrultusunda 38,748 kayıtlıüretici tarafından 216,863.10 ha üretim alanı, 24,334.03 ha doğadan toplamaalanı ve 2,581.71 ha nadas alanı ile birlikte toplam 243,778.85 ha alandaüretim yapılmakta ve bu alanda toplam 1,101,236.97 ton bitkisel üretimyapılmaktadır. Bu verilere geçiş süreci ürünleri dâhil edilmemiştir. The first officialorganic farming movement in Turkey started in 1992 with the establishment ofthe Ecological Agriculture Organization. Later, activities related to organicagriculture have been carried out under the Ministry of Food, Agriculture andLivestock, General Directorate of Plant Production since 2003, together withits legislation. Organic agricultural activities are carried out within theframework of the provisions of the "Organic Agriculture Law" numbered5262, which entered into force in 2004, and the "Regulation on thePrinciples and Implementation of Organic Agriculture", which has been ineffect since 2006. In addition, Organic Agriculture Transition Process isincluded in organic agriculture in accordance with the provisions of the“Regulation on the Principles and Implementation of Organic Agriculture” dated18.08.2010 and numbered 27676. Organic agriculture, which is a controlled andcertified system at every stage, is carried out at international standards bycomplying with the EU Organic Agriculture Legislation. In line with the data of2021, production is carried out by 38,748 registered producers on a total areaof 243,778.85 hectares, including 216,863.10 ha production area, 24,334.03 hanatural collection area and 2,581.71 ha fallow area, and a total of1,101,236.97 tons of crop production is made in this area. Products transitionperiod are not included in these data.
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33. Organik Tarımda Sürdürülebilir Toprak Verimliliği
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Bulut, Sancar
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Artan dünya nüfusunu besleme kaygısıyla ortayaçıkan yoğun ve yanlış tarımsal uygulamalar; toprağı yormakta, verimliliğiniazaltmakta, insan, hayvan ve bitki sağlığını olumsuz etkilemekte, bununsonucunda doğal yapının bozulmasına neden olmaktadır. Ancak günümüzde çevrebilinci ve insan sağlığına verilen önem her geçen gün artmakta, gelenekseltarıma alternatif olabilecek tarım sistemleri gündeme gelmektedir. Toprakların sürdürülebilir kullanımı için iyibir alternatif olan organik tarım; ekolojik, ekonomik ve sosyalsürdürülebilirliği amaçlayan, toprak verimliliğini, çevrenin korunmasını vegıda güvenliğini esas alan bir tarım sistemidir. Organik tarımda; iyi birtoprak ve bitkisel ürün verimliliği için toprağı yıpratıcı tüm faaliyetlerdenuzak durulmalı ve toprağı muhafaza edici önlemler alınmaktadır. Bu amaçlateraslama, çevirme, malçlama, şeritvari ekim, örtü bitkisi, yeşil gübre,kompost, çiftlik gübresi, anızlı tarım, koruyucu toprak işleme gibi toprakbozulması ve kayıplarını engelleyen fiziksel ve kültürel tedbirleruygulanmaktadır. Bu derlemede; toprak verimliliğinin korunmasını,geliştirilmesini ve toprakların sürdürülebilir kullanımını sağlayacak organiktarım kapsamındaki uygulamalar anlatılacaktır. Intensive and improper agricultural practices, which arise with theconcern of feeding the increasing world population, exhaust the soil, reduceits productivity, adversely affect human, animal and plant health, and as aresult change ecological balance. However, nowadays, the attention given toenvironmental awareness and human health is increasing day by day, andagricultural systems that can be an alternative to traditional agriculture areon the agenda. Organic farming, a good alternative for sustainable use of soils,is an agricultural system that concern ecologic, economic and socialsustainability and is based on soil fertility, environmental protection andfood security. In organic agriculture; for a good soil and crop productivity,it is far from all activities that weaken the soil, on the contrary, measuresare taken to protect the soil. For this purpose, physical and cultural measuresare applied to prevent soil degradation and losses such as terracing, overturning,mulching, strip-like planting, cover crops, green manure, compost, farm manure,stubble farming, and protective tillage. In this review; applications withinthe scope of organic farming that will ensure to keep and increase soilfertility and the sustainable use of soils will be discussed.
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34. Outcomes of Limb Lengthening with Computer-assisted Hexapod External Fixators in the Treatment of Fibular Hemimelia
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Sancar Bakircioglu, Barlas Goker, Abdurrahman Yilmaz, Taha Aksoy, Mehmet Cemalettin Aksoy, and Guney Yilmaz
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Pediatrics, Perinatology and Child Health ,Orthopedics and Sports Medicine ,General Medicine - Published
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35. The Use of Virtual Reality in Education for Sustainable Development
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Raziye Sancar, Deniz Atal, and Hüseyin Ateş
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Environmental sustainability is one of the major global topics of the 21st century. In order to effectively include the concept of sustainability in the topic of environmental education, educators are responsible for incorporating the concept into the existing curriculum. However, it may not always be possible to conduct field studies based on environmental education due to economic, transport, and time constraints, while certain situations and conditions may be particularly difficult to replicate. One recent solution to this problem is the application of Virtual Reality technology, which has been shown in various recent studies. VR is a computer-generated three-dimensional environment that allows the user to perceive content more realistically. In the process of teaching sustainability issues such as climate change, waste management, food consumption, air and water pollution, and deforestation, the present study has revealed that cooperation between different fields of expertise, including science education and computer and instructional technologies, plays an important role.
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36. The Fate of Overcorrection After Hemiepiphysiodesis in Valgus Deformities Around the Knee
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Taha Aksoy, Sancar Bakircioglu, Erdi Ozdemir, Rafik Ramazanov, Mehmet Cemalettin Aksoy, and Guney Yilmaz
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Pediatrics, Perinatology and Child Health ,Orthopedics and Sports Medicine ,General Medicine - Published
- 2023
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37. Nucleotide excision repair in Human cell lines lacking both XPC and CSB proteins
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Laura A Lindsey-Boltz, Yanyan Yang, Cansu Kose, Nazli Deger, Khagani Eynullazada, Hiroaki Kawara, and Aziz Sancar
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Genetics - Abstract
Nucleotide excision repair removes UV-induced DNA damage through two distinct sub-pathways, global repair and transcription-coupled repair (TCR). Numerous studies have shown that in human and other mammalian cell lines that the XPC protein is required for repair of DNA damage from nontranscribed DNA via global repair and the CSB protein is required for repair of lesions from transcribed DNA via TCR. Therefore, it is generally assumed that abrogating both sub-pathways with an XPC−/−/CSB−/− double mutant would eliminate all nucleotide excision repair. Here we describe the construction of three different XPC−/−/CSB−/− human cell lines that, contrary to expectations, perform TCR. The XPC and CSB genes were mutated in cell lines derived from Xeroderma Pigmentosum patients as well as from normal human fibroblasts and repair was analyzed at the whole genome level using the very sensitive XR-seq method. As predicted, XPC−/− cells exhibited only TCR and CSB−/− cells exhibited only global repair. However, the XPC−/−/CSB−/− double mutant cell lines, although having greatly reduced repair, exhibited TCR. Mutating the CSA gene to generate a triple mutant XPC−/−/CSB−/−/CSA−/− cell line eliminated all residual TCR activity. Together, these findings provide new insights into the mechanistic features of mammalian nucleotide excision repair.
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38. AGRICULTURE AND ENVIRONMENT INTERACTION
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Sancar Bulut and Zeki Gökalp
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Cultural Studies ,Religious studies - Abstract
The resources necessary for food production have shown a disquieting deterioration during the last three decades. Modern intensive agriculture has an adverse effect not only on the physical environment but also on human health. On the other hand, 'Sustainable Agricultural Systems', which has gained importance in recent years, deals with both the protection of natural resources and the increase in plant production. In these systems, production is ensured by directing the resources obtained from the system cycle, not the chemicals and inputs that harm human, plant and environmental health, and quality healthy products are obtained. In 'Organic Farming', which is one of the sustainable agricultural systems, it is aimed to cause the least damage to the environment by producing healthy foods without disturbing the natural balance. The risk of pollution is less because less economic input is used in these and similar protected sustainable agricultural systems. While the inputs used in agricultural production stage increase the productivity of the product produced per unit area and make it more resistant to diseases and pests, they can have negative effects on the living things in the immediate vicinity and the ecosystem. While the development of agriculture in a region positively affects the natural life, oxygen production and climate in the region, inorganic nitrate pollution, pesticide pollution and salinity problems can be listed as the negative effects of agriculture on the environment, especially in regions where intensive agriculture is practiced. Also, agricultural water use, application of fertilizers and pesticides may negatively affect the water courses, deforestation, and crop and animal raising may result in greenhouse gas emissions, unsuitable agricultural practices may have detrimental impacts on soil, genetic resources and biodiversity. In order to ensure sustainability in agriculture, by abandoning the agricultural production methods based on excessive chemical pesticides and fertilizers that the producers have applied until now; an economical fertilization, preserving the organic matter ratio of the soil by preventing stubble fires, reduced tillage, combating diseases, pests and weeds in integration with a suitable crop rotation are of great importance.
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39. POTENTIAL USE OF BIOCHAR IN WASTEWATER TREATMENT OPERATIONS AND SOIL IMPROVEMENT
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Zeki Gokalp and Sancar Bulut
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Cultural Studies ,Religious studies - Abstract
Biochar is produced through thermochemical decomposition, so called as pyrolysis, of different biomass groups in the presence of little or no oxygen. Resultant material is highly stable material with excellent surface characteristics and pore structure and is also rich in functional groups. Such properties of the material are largely influenced by pre- and post-treatments and thermal decomposition conditions. Various methods have been used for thermal decomposition of biomass, such as pyrolysis thermal carbonization, torrefaction and microwave heating at different temperatures and for different durations. Biochar has recently started to be used for wastewater treatment and water pollution control purposes. It is also used to improve soil properties including aggregate stability, water holding capacity and organic matter content. It is a new, economic and environment friendly material to be used in wastewater treatments technology and soil improvement. In this study, biochar production technologies and properties of resultant materials were summarized and potential use of biochar in wastewater treatments operations and for soil improvement were assessed in detail.
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40. Effect of the Lumbar Sympathetic Block on Pain in Patients with Symptomatic Peripheral Arterial Disease-Retrospective Analysis
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Samet Sancar Kaya, Seref Celik, Erkan Yavuz Akcaboy, Hamit Goksu, Mustafa Yemliha Ayhan, and Saziye Sahin
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Anesthesiology and Pain Medicine - Abstract
Objective: To study the effect of lumbar sympathetic block (LSB) with a mixture of local anesthetics and steroids on pain in patients with chronic ischemic lower limb disease. Methods: Retrospectively 23 patients were reviewed with peripheral arterial disease who underwent LSB using a mixture of 8 mg of dexamethasone, 80 mg of 2% lidocaine, and 4 mL of saline at 2 levels, L2 and L4, under the guidance of fluoroscopy. Recordings of the Visual Analog Scale (VAS) scores at 3 days before the blockage, and 1 month and 3 months after treatment were obtained. Results: The study included 20 (87%) male and 3 (13%) female patients. The mean age of the patients was 59.65±13.33 years. The patients’ post-blockage 3rd day, and 1st and 3rd month VAS scores were significantly lower than the baseline VAS scores (p
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41. Impact of Political Violence on People in Istanbul: The Role of Resilience in Posttraumatic Stress and Psychological Health
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Funda Sancar and Ayten Zara
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Psychiatry and Mental health ,Clinical Psychology ,Health Professions (miscellaneous) - Published
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42. Resiliency-Driven Multi-Step Critical Load Restoration Strategy Integrating On-Call Electric Vehicle Fleet Management Services
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Ayse Kubra Erenoglu, Semanur Sancar, Idil Su Terzi, Ozan Erdinc, Miadreza Shafie-Khah, and Joao P. S. Catalao
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General Computer Science - Published
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43. Investigation of Antimicrobial Activities of Extracts of Some Plant Sources Prepared in Different Solvents
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Burcu SANCAR BEŞEN, Leyla EREN KARAHAN, Pınar PARLAKYİĞİT, Cumhur KIRILMIŞ, and Sakine ERDOĞAN
- Abstract
In the present study, it was aimed to research the antimicrobial activities of prepared extracts of some plant sources such as aloe vera (Aloe barbadensis), marigold (Calendula officinalis), maidenhair fern (Adiantum capillus-veneris Linn.) and bitter melon (Momordica charantia) by using different solvents. For this purpose, the extracts of the plants in the solvents as n-hegzan, ethanol, methanol and distilled water were prepared via maceration process. Either antibacterial activies against Staphylococcus aureus and Escherichia coli or antifungal activities against Aspergillus niger of the prepared extracts were investigated. The results demonstrated that the plant sources and solvent types used in the extraction are crucial on the antimicrobial activities of the extracts.
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- 2022
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44. Kayseri ikinci ürün şartlarında bazı mısır çeşitlerinin silajlık performanslarının değerlendirilmesi
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Sancar Bulut
- Subjects
Silage corn,Second crop,Adaptation,Yield,Kayseri ,Silajlık mısır,İkinci ürün,Adaptasyon,Verim,Kayseri ,Agronomi ,Agronomy - Abstract
This study was carried out in the experimental fields of Erciyes University Agricultural Research and Application Center in 2014 and 2015 growing seasons, in order to investigate the possibilities of second crop silage maize production in Kayseri province. Twenty-four corn cultivars were evaluated for silage performance. In the evaluation, all measured parameters differed significantly, except the number of ears per plant. According to the two-year average results; cultivar Hido had the the shortest emergence period and while cultivar PR31D24 had the longest emergence period. The BC5610, BC8605 and Hido were the earliest cultivars to reach the silage maturity through forming ear and tassel silkings. On the other hand, the PR31D24 and PR31G98 were the latest cultivars to reach the silage maturity. While the cultivars DKC-5783 and Hacibey had the highest number of ear per plant, the cultivar Oran (0.7) had the least number of ear per plant. In the present study, the highest number of leaves was obtained from Korimbos and Hacıbey cultivars, and the least was obtained from KWS 6565 cultivar. The highest herbage yield was obtained from cultivar Oran with 53681 kg/ha, and the lowest herbage yield was obtained from KWS 6565 variety with 33174 kg/ha. In line with these results, Hido, BC 5610 and BC 8605 were the earliest cultivars for silage maturity, however, in terms of herbage yield, number of ears and leaves per plant, Oran, DKC-5783, Hacıbey and Korimbos cultivars were the most promising cultivars under second crop conditions in Kayseri and similar ecologies., Bu çalışma, Kayseri koşullarında ikinci ürün silajlık mısır üretim olanaklarını araştırmak amacıyla Erciyes Üniversitesi Tarımsal Araştırma ve Uygulama Merkezine ait uygulama alanında, 2014 ve 2015 yıllarında ikinci ürün şartlarında yürütülmüştür. Bitki materyali olarak, tescil listesinde yer alan 24 mısır çeşidi değerlendirilmiştir. Yapılan değerlendirmede, bitki başına koçan sayısı hariç ölçülen tüm parametreler önemli derecede farklılık göstermiştir. İki yıllık ortalama sonuçlara göre; çeşitlerden çıkış süresi en kısa olan Hido çeşidi, çıkış süresi en uzun olan ise PR31D24 çeşidi olmuştur. BC5610, BC8605 ve Hido çeşitleri en kısa sürede tepe ve koçan püskülü çıkarıp silaj için olgunlaşan çeşitler olmuştur. Diğer yandan en geç tepe ve koçan püskülü çıkararak en geç silaj için hasada ulaşan çeşitler de PR31D24 ve PR31G98 olmuştur. Koçan sayısı en fazla olan DKC-5783 ve Hacıbey çeşitleri, koçan sayısı en az olan çeşit ise Oran (0.7 adet bitki-1) olarak tespit edilmiştir. Denemede en fazla yaprak sayısı Korimbos ve Hacıbey çeşitlerinde, en az ise KWS 6565 çeşidinde tespit edilmiştir. En yüksek hasıl verimi 5368.1 kg da-1 ile Oran çeşidinde, en düşük ise 3317.4 kg da-1 ile KWS 6565 çeşidinden elde edilmiştir. Bu sonuçlar doğrultusunda, erkencilik yönünden Hido çeşidi başta olmak üzere silaj için hasat olgunluğuna en erken ulaşan BC 5610 ve BC 8605 çeşitleri, hasıl verimi, bitki başına koçan ve yaprak sayısı gibi karakterler yönünden ise daha yüksek değerlere sahip olan Oran, DKC-5783, Hacıbey ve Korimbos çeşitlerinin Kayseri ve benzer ekolojilerde ikinci ürün şartlarında ümit var oldukları bulunmuştur.
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- 2022
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45. Endometrium kanserli obez hastalarda laparoskopik ve açık cerrahinin karşılaştırılması
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SANCAR, Ceren, YILDIRIM, Nuri, BILGI, Ahmet, GOKULU, Sevki, AKMAN, Levent, COŞAN TEREK, Mustafa, and AYDIN ÖZSARAN, Ahmet
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Health Care Sciences and Services ,Laparoskopi,laparotomi,endometrial kanser ,Sağlık Bilimleri ve Hizmetleri ,Laparoscopy,laparotomy,endometrial carcinoma - Abstract
Amaç: Çalışmanın amacı endometrial kanserli obez hastalarda total laparoskopik histerektomi ve total abdominal histerektomi sonuçlarının karşılaştırılmasıdır. Gereç ve Yöntem: Vücut kitle oranı ≥30 kg/m2 olan endometrial kanserli hastalardan total laparoskopik histerektomi (n=68) ve total abdominal histerektomi (n=161) uygulanmış olanlar çalışmaya dahil edildi. Hastaların demografik ve histopastolojik özellikleri, hastalıksız sağ kalım ve toplam sağ kalım süreleri kaydedildi. Laparoskopi ve laparotomi grubunun verileri birbirleri ile karşılaştırıldı.Bulgular: k grup arasında, evre, tümör derecesi, histoloji, lenf nodu diseksiyonu yapılma oranı ve çıkarılan lenf nodu sayısı açısından anlamlı fark görülmedi. ard yovasküler hastalıklar laparotom grubunda belirgin fazla izlendi (p=0,002). ASA (Amerikan Anestezistler Derneği) skoru laparotomi grubunda daha yüksek idi (p=0,001). Peroperatif ve postoperatif komplikasyonlar laparotomi ve laparoskopi gruplarında benzer idi. Laparatomi grubunda; operasyon süresi belirgin kısa iken, postoperatif hastanede yatış süres laparoskop grubuna göre belirgin artmış idi (p, Aim: The aim of the study is to compare the results of total laparoscopic hysterectomy and total abdominal hysterectomy in obese women with endometrial cancer (EC). Materials and Methods: Patients with endometrial cancer whose BMI ≥30 kg/m2 and who were undergone total laparoscopic hysterectomy (n=68) or total abdominal hysterectomy (n=161) were included in the study. Demographic and histopathological features, disease-free survival and overall survival of the patients were recorded. All these data of laparoscopy and laparotomy patients were compared with each other.Results: No significant difference was observed between two groups in terms of stage, tumor grade, histology, lymph node dissection rate and number of removed lymph nodes. Cardiovascular diseases were more common in laparotomy group (p=0.002). ASA (American Society of Anesthesiologists) score was higher in laparotomy group (p=0.001). Perioperative and postoperative complications were similar in both groups. The operation time was significantly longer and postoperative hospital stay was significantly shorter in the laparoscopy group (p
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- 2022
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46. Metabolic Messengers: fibroblast growth factor 1
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Emanuel Gasser, Gencer Sancar, Michael Downes, and Ronald M. Evans
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Fibroblast Growth Factors ,Physiology (medical) ,Endocrinology, Diabetes and Metabolism ,Internal Medicine ,Fibroblast Growth Factor 1 ,Cell Biology ,Article - Abstract
While fibroblast growth factor (FGF) 1 is expressed in multiple tissues, only adipose-derived and brain FGF1 have been implicated in the regulation of metabolism. Adipose FGF1 production is upregulated in response to dietary stress and is essential for adipose tissue plasticity in these conditions. Similarly, in the brain, FGF1 secretion into the ventricular space and the adjacent parenchyma is increased after a hypercaloric challenge induced by either feeding or glucose infusion. Potent anorexigenic properties have been ascribed to both peripheral and centrally injected FGF1. The ability of recombinant FGF1 and variants with reduced mitogenicity to lower glucose, suppress adipose lipolysis and promote insulin sensitization elevates their potential as candidates in the treatment of type 2 diabetes mellitus and associated comorbidities. Here, we provide an overview of the known metabolic functions of endogenous FGF1 and discuss its therapeutic potential, distinguishing between peripherally or centrally administered FGF1.
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- 2022
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47. Persistent right heart dilatation after percutaneous mitral balloon valvuloplasty: A weird coexistence of iatrogenic and congenital shunts
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Arda Guler, Cagdas Topel, Kadriye Memic Sancar, Gökhan Kahveci, Burak Onan, Gamze Babur Guler, İstinye Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, and Kahveci, Gokhan
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Iatrogenic Atrial Septal Defect ,Pregnancy ,Pulmonary Venous Return Abnormality ,Rheumatic Mitral Stenosis ,Radiology, Nuclear Medicine and imaging ,Cardiology and Cardiovascular Medicine - Abstract
We present an interesting case of concomitant congenital anomalies with an iatrogenic defect. The female patient underwent a percutaneous mitral balloon valvuloplasty due to rheumatic mitral stenosis. Unfortunately, an iatrogenic atrial septal defect (ASD) transpired during the procedure. Upon post-procedure examination, partial anomalous pulmonary venous (PAPVR) return was observed. The patient was symptomatic; on imaging, dilatation of the right heart chambers were detected. In addition, another crucial point was that the patient was planning a pregnancy, thus robotic surgery for iatrogenic ASD and PAPVR return was recommended. After a successful operation, the patient was asymptomatic and the size of right heart chambers were normalized. © 2022 Wiley Periodicals LLC. 2-s2.0-85131369960
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- 2022
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48. Mineral Composition of Bread Wheat Cultivars as Influenced by Different Fertilizer Sources and Weed Management Practices
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Sancar Bulut, Ali Özturk, Nesrin Yıldız, and Mehmet Murat Karaoğlu
- Subjects
General Agricultural and Biological Sciences - Abstract
Mineral and vitamin deficiencies are one of the important threats especially in developing and under-developed countries. Wheat grain also contains a number of elements vital to our biological functions, but hazardous to our health in high concentrations. This research was carried out to determine the effects of agronomic practices on the mineral composition of organically grown bread wheat (Triticum aestivum L.) varieties. In terms of all nutrients evaluated, the mineral content of wheat showed significant differences according to crop years, varieties, weed management methods and fertilizer sources. As the average of all factors, the Cu, Fe, Mn, Se, Zn, Cd, Co, Cr, Ni and Pb contents of the ground wheat grain were 3.93, 42.8, 79.6, 0.549, 11.34, 0.012, 0.140, 0.194, 3.71 and 0.269 mg/kg, respectively. According to the wheat varieties, the Kirik was superior in terms of Cu (7.6%), Fe (3.8%), Se (57%), Zn (40.5%), Co (31.1%) and Cr (36.1%), and the Dogu-88 was superior in terms of Mn (5.5%), Cd (1.9%), and Ni (17.0%). The effect of weed management methods on mineral content was variable. According to fertilizer sources, the highest mineral content was obtained from the control plots without fertilizer treatments. The lowest mineral contents were obtained from chemical fertilization, cattle manure and organic fertilizer applications. There was no significant increase in the mineral content of wheat with organic fertilization, however, organic agriculture still preserves its place in terms of healthy food. As a result, it has been determined that the values obtained for all mineral elements were not at a level that pose a risk on the environment, human and animal health according to WHO. In order to identify wheat varieties with higher mineral content, which are beneficial for human health, new research should be done with different organic fertilizer sources with more varieties.
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- 2022
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49. Deprem yaralanmaları ve ampütasyon, gözlemlerimiz ve önerilerimiz
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Mehmet Fethi Ceylan, Sancar Serbest, and Necip Güven
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- 2022
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50. Validation of a Knowledge Test in Turkish Patients on Warfarin Therapy at an Ambulatory Anticoagulation Clinic
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Refik Demirtunç, Osman Uzman, Mesut Sancar, Nazlıcan Uçar, Pinar Ay, Betül Okuyan, Meltem Turker, Ömer Kozan, Turker, Meltem, Sancar, Mesut, Demirtunc, Refik, Ucar, Nazlican, Uzman, Osman, Ay, Pinar, Kozan, Omer, and Okuyan, Betul
- Subjects
knowledge ,medicine.medical_specialty ,Turkish ,medicine.drug_class ,pharmacist ,education ,Pharmacist ,Pharmaceutical Science ,Validity ,ADHERENCE ,Internal medicine ,medicine ,Outpatient clinic ,business.industry ,anticoagulant ,Anticoagulant ,Warfarin ,ASSOCIATION ,language.human_language ,Test (assessment) ,Ambulatory ,language ,Molecular Medicine ,TRIAL ,Original Article ,business ,medicine.drug - Abstract
Objectives: This study aimed to evaluate the validity and reliability of an oral anticoagulation knowledge (OAK) test in Turkish patients on warfarin therapy at an anticoagulant outpatient clinic. Materials and Methods: This study was conducted at an ambulatory anticoagulation clinic and included patients older than 18 years who had been using warfarin for at least six months. Patients' demographic and clinical data were collected. Internal consistency was calculated using the Kuder-Richardson 20 (KR-20) coefficient, and the test-retest reliability of the Turkish version of the OAK test was assessed. Results: Patients' mean age was 59.83 +/- 11.93 (26-90) years (n=240; 133 women). The mean score of the OAK test was 14.19 +/- 3.01. The test-retest reliability of the scale (n=30) was moderate for the total score (p
- Published
- 2021
- Full Text
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