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1. The BFMNU method as an alternative to the methods in use based on energy: study of the correlation between food energy and body mass

Author

Rondini, G, Olearo, B, del Castillo, JMS, and Boselli, PM

Subjects
Body mass changes, Food mass intake, Human energy expenditure, Energy intake
Abstract

Introduction: to establish slimming guidelines and any other changing treatments is useful to know the individual's energy expenditure due to the fact that, nowadays, the incidence of many diseases related to the loss of lean mass and the accumulation of adipose tissue has increased. The dietary treatments are carried out on calculating the energy contained in food, and then put in relation to the total energy expended by the body in order to produce changes in body mass. Objective: the aim of this study was to evaluate the correlation between the food energy and body mass of different subjects in various pathophysiological conditions. Methods: one hundred and twenty subjects (male and female, aged 7-78 years old) were studied in various pathophysiological conditions and previously treated with the BFMNU (Biologic e Fisiologia Modellistica della Nutrizione Umana) method. Results: a correlation coefficient R-2 of 0.1256 was found between food energy of the diet usually followed by the subjects and their body mass. The correlation between food energy and food mass was with R-2 of 0.211. The correlation between Delta% of food energy and Delta% of body mass of the subjects, obtained through dietary treatment with the BFMNU method, was 95.77 percent. Conclusions: the correlation between food energy and body mass is not significant, being a critical point about the diets designed on an energy basis. However, the body mass of an individual is determined by mass balance, regulated by corresponding metabolic rate, calculated by the BFMNU method, thanks to which the macronutrients in the diet are absorbed, redistributed and eliminated. A significant correlation, although not straight, is demonstrated between Delta% of food energy, supplied after processing through the dietary BFMNU method, and the Delta% of body mass, obtained following the dietetic path.

Published
2018

2. The Quality of Life of Children and Adolescents with X-Linked Agammaglobulinemia

Author

Soresina A., Nacinovich R., Bomba M., Cassani M., Molinaro A., Sciotto A., Martino S., Cardinale F., De Mattia D., Putti C., Dellepiane R.M., Felici L., Parrinello G., Neri F., Plebani A., Pierani P., DeMattia D., Martire B., Armenio L., Dammacco F., Ranieri G., Masi M., Miniaci A., Pession A., Rondelli R., Notarangelo L. D., Cao, Cossu F., Del Giacco S., Manconi P., Evangelista I., Magro S., Morgione S., STRISCIUGLIO, PIETRO, Anastasio E., Schillirò G., Paganelli R., Sticca M., Sperlì D., Carpino L., Bernini G., Azzari C., Maggi E., Romagnani S., Matucci A., Vultaggio A., Castagnola E., Gattorno M., Presta G., Civino A., Gambaretto G., Fasoli S., Salpietro C., Pietrogrande M.C., DellePiane R.M., Panisi C., Cambiaghi G., Pietrogrande M., Roncarolo M.G., Aiuti A., Masera G., Biondi A., Sala A., PIGNATA, CLAUDIO, Poggi V., Menna G., Di Nardo R., D'Apuzzo A., Pelliccia A., Correra A., Marone G., SPADARO, GIUSEPPE, Carli M., Zanesco L., Basso G., Putti M.C., Semenzato G., Agostini C., Amato G.M., Aricò M., Trizzino A., Izzi G., Bertolini P., Locatelli F., Zecca M., Rondini G., Marseglia G.L., Maccario R., Bossi G., Favre C., Consolini R., Vecchi V., Sacchini P., Rinaldi G., Ugazio A.G., Rossi P., Livadiotti S., Cancrini C., Finocchi A., Stabile A., Duse M., Iacobini M., Quinti I., Moschese V., Cecere F., Morgese G., Acquaviva A., De Zan G., Strafella S., Tamaro P., Rabusin M., Tovo P.A., Nespoli L., Marinoni M., Porcellini A., Cazzola G.A., Annarosa, Soresina, Renata, Nacinovich, Monica, Bomba, Morena, Cassani, Molinaro, Anna, Antonella, Sciotto, Silvana, Martino, Fabio, Cardinale, Domenico, Mattia, Caterina, Putti, Rosa Maria, Dellepiane, Leonardo, Felici, Giovanni, Parrinello, Francesca, Neri, Alessandro, Plebani, Soresina, A, Nacinovich, R, Bomba, M, Cassani, M, Molinaro, A, Sciotto, A, Martino, S, Cardinale, F, De Mattia, D, Putti, C, Dellepiane, R, Felici, L, Parrinello, G, Neri, F, Plebani, A, Soresina, A., Nacinovich, R., Bomba, M., Cassani, M., Molinaro, A., Sciotto, A., Martino, S., Cardinale, F., De Mattia, D., Putti, C., Dellepiane, R. M., Felici, L., Parrinello, G., Neri, F., Plebani, A., Pierani, P., Demattia, D., Martire, B., Armenio, L., Dammacco, F., Ranieri, G., Masi, M., Miniaci, A., Pession, A., Rondelli, R., Notarangelo, L. D., Cao, Cossu, F., Del Giacco, S., Manconi, P., Evangelista, I., Magro, S., Morgione, S., Strisciuglio, Pietro, Anastasio, E., Schillirò, G., Paganelli, R., Sticca, M., Sperlì, D., Carpino, L., Bernini, G., Azzari, C., Maggi, E., Romagnani, S., Matucci, A., Vultaggio, A., Castagnola, E., Gattorno, M., Presta, G., Civino, A., Gambaretto, G., Fasoli, S., Salpietro, C., Pietrogrande, M. C., Panisi, C., Cambiaghi, G., Pietrogrande, M., Roncarolo, M. G., Aiuti, A., Masera, G., Biondi, A., Sala, A., Pignata, Claudio, Poggi, V., Menna, G., Di Nardo, R., D'Apuzzo, A., Pelliccia, A., Correra, A., Marone, G., Spadaro, Giuseppe, Carli, M., Zanesco, L., Basso, G., Putti, M. C., Semenzato, G., Agostini, C., Amato, G. M., Aricò, M., Trizzino, A., Izzi, G., Bertolini, P., Locatelli, F., Zecca, M., Rondini, G., Marseglia, G. L., Maccario, R., Bossi, G., Favre, C., Consolini, R., Vecchi, V., Sacchini, P., Rinaldi, G., Ugazio, A. G., Rossi, P., Livadiotti, S., Cancrini, C., Finocchi, A., Stabile, A., Duse, M., Iacobini, M., Quinti, I., Moschese, V., Cecere, F., Morgese, G., Acquaviva, A., De Zan, G., Strafella, S., Tamaro, P., Rabusin, M., Tovo, P. A., Nespoli, L., Marinoni, M., Porcellini, A., and Cazzola, G. A.

Subjects
Male, Pediatrics, medicine.medical_specialty, x-linked agammaglobulinemia, Activities of daily living, Adolescent, X-linked agammaglobulinemia, Health Status, Immunology, pedsql 4.0 generic core scale, Quality of life, children, Agammaglobulinemia, Surveys and Questionnaires, Activities of Daily Living, health-related quality of life, parents, medicine, Humans, Immunology and Allergy, PedsQL 4.0 Generic Core Scale, Child, Settore MED/38 - Pediatria Generale e Specialistica, Health related quality of life, quality of live, business.industry, Immunoglobulins, Intravenous, Genetic Diseases, X-Linked, medicine.disease, Socioeconomic Factors, Child, Preschool, Mutation, Quality of Life, Female, X-linked agammaglobulinemia - children - parents - health-related quality of life - PedsQL 4.0 Generic Core Scale, business
Abstract

Introduction: The health-related quality of life in X-linked agammaglobulinemia was investigated in 25 children and adolescents patients through the Italian version of Pediatric Quality of Life Inventory 4.0 Generic Core Scale for patients aged less then 18 years, comparing child perception to that of the parents and the physician's evaluation. The data were compared with the ones of 80 healthy controls and the literature data of a group of patients with rheumatic diseases. Discussion: The agammaglobulinemia subjects perceived a lower global quality of life than the healthy subjects, but significantly higher than the rheumatic diseases controls. The clinical relevance of health-related quality of life assessment in X-linked agammaglobulinemia pediatric patients is discussed. © 2008 Springer Science+Business Media, LLC.

Published
2009

4. Do differences in delivery room intubation explain different rates of bronchopulmonary dysplasia between hospitals?

Author

Gagliardi, Luigi, Bellù, Roberto, Lista, Gianluca, Zanini, Rinaldo, Compagnoni, G., Mosca, F., Martinelli, S., Chirico, G., Santucci, S., Caccamo, M. L., Maccabruni, M., Stronati, M., Rondini, G., Agosti, M., Magni, L. A., Moro, G., Tagliabue, P., Barera, G., Merazzi, D., Cavazza, A., Brunelli, A., Battaglioli, M., Tandoi, F., Cella, D., Perotti, G. F., Pelti, M., Stucchi, I., Frisone, F., Avanzini, A., Bastrenta, P., Iacono, G., Pontiggia, F., Cotta-Ramusino, A., Strano, F., Fontana, P., Franco, M., Rossi, L., Calciolari, G., Citterio, G., Rovelli, R., Poloniato, A., Gancia, G. P., Costato, C., Germani, R., Barp, S., Crossignani, R., Siliprandi, N., Borroni, C., Ventura, M. L., Abbiati, L., Giardinetti, S., Leva, L., Fusi, M., and Bellasio, M.

Subjects
Male, Birth weight, medicine.medical_treatment, Gestational Age, Pediatrics, law.invention, Case mix index, law, Risk Factors, mental disorders, Intubation, Intratracheal, Medicine, Intubation, Birth Weight, Humans, Infant, Very Low Birth Weight, Bronchopulmonary Dysplasia, Mechanical ventilation, business.industry, Pediatrics, Perinatology and Child Health, Obstetrics and Gynecology, Delivery Rooms, Infant, Newborn, Gestational age, General Medicine, Perinatology and Child Health, medicine.disease, Respiration, Artificial, Bronchopulmonary dysplasia, Italy, Anesthesia, Ventilation (architecture), Small for gestational age, Female, business, Infant, Premature
Abstract

To investigate whether the wide variation in the frequency of bronchopulmonary dysplasia (BPD) between hospitals is due to differences in delivery room intubation rates.Data on 1260 infants of birth weight1500 g and 23-31 weeks gestational age, born in 1999-2002 and surviving to 36 weeks, were collected; 196 (15.6%) developed BPD defined as oxygen need at 36 weeks postmenstrual age. Generalised estimating equations and conditional logistic models adjusting for centre, gestational age, propensity score for intubation, and other potential confounders were used.Rates of BPD, delivery room intubation and mechanical ventilation for24 h differed significantly between hospitals. Centres with high delivery room intubation rates had higher ventilation and BPD rates. Hospitals ventilating more often also did so for a longer time. Although delivery room intubation was associated with BPD in unadjusted analyses, neither delivery room intubation nor brief (24 h) mechanical ventilation were risk factors for BPD in multivariate analyses adjusting for gestational age, case mix and other pre- and perinatal factors, indicating no causal effect or unmeasured confounding. Significant risk factors for developing BPD were low gestational age, prolonged ventilation (24 h: adjusted OR (aOR) 2.4;7 days: aOR 14.9), male sex (aOR 1.7), being small for gestational age (SGA; aOR 4.3) and late-onset sepsis (aOR 2.2). After taking into account these variables/procedures, centre differences remained significant but explained only about 5% of variance.Differences in BPD frequency between hospitals are explained by differences in procedures, chiefly mechanical ventilation, rather than by differences in initial management or case mix. Delivery room intubation and brief mechanical ventilation did not increase BPD risk.

Published
2011

5. Prevalence, exclusivity, and duration of breast-feeding in Lombardia

Author

Macchi, L., Pirola, M. E., Monaco, G., Pavan, A., Bettinelli, M. E., Zapparoli, B., Agosti, M., Bonati, M., Banderali, G., Colombo, A., Giovannini, M., Mosca, F., Narducci, M., Nino, M. L., Rondini, G., Speri, L., Riva, E., and Fortinguerra, F.

Published
2008

6. Prevalenza, esclusività e durata dell'allattamento al seno in Lombardia

Author

Macchi, L., Pirola, M. E., Monaco, G., Pavan, A., Bettinelli, M. E., Zapparoli, B., Agosti, M., Bonati, M., Banderali, G., Colombo, A., Giovannini, M., Mosca, F., Narducci, M., Nino, M. L., Rondini, G., Speri, L., Riva, E., and Fortinguerra, Filomena

Subjects
Medicine (all)
Published
2008

9. Prophylactic nasal continuous positive airways pressure in newborns of 28-31 weeks gestation: multicentre randomised controlled clinical trial

Author

Sandri, F, Ancora, G, Lanzoni, A, Tagliabue, P, Colnaghi, M, Ventura, Ml, Rinaldi, M, Mondello, I, Gancia, P, Salvioli, Gp, Orzalesi, M, Mosca, F, Brasca, E, Fedeli, T, Pelti, M, Germani, R, Costato, C, Maffei, G, Rinaldi, G, Morgando, Mp, Cambursano, P, Strano, F, Rondini, G, Santuz, P, Biban, P, Gitto, Eloisa, Cordaro, S, Cordaro, P, Barberi, Ignazio, Gargano, G, Roversi, Mf, Ferrari, F, Compagnoni, G, Lista, G, Castoldi, F, Giordano, L, Messina, F, Napolitano, M, Marra, A, Dani, C, Rubaltelli, F, Bonacci, W, Serra, G, Piccinini, G, Santini, G, Martano, C, and Fabris, C.

Subjects
Male, newborns, medicine.medical_treatment, Partial Pressure, positive airways pressure, Drug Administration Schedule, Intensive care, medicine, Clinical endpoint, Humans, Continuous positive airway pressure, Mechanical ventilation, Respiratory Distress Syndrome, Newborn, Respiratory distress, Continuous Positive Airway Pressure, business.industry, Incidence (epidemiology), Infant, Newborn, Obstetrics and Gynecology, Pulmonary Surfactants, General Medicine, respiratory system, Clinical trial, Oxygen, Anesthesia, Pediatrics, Perinatology and Child Health, Intensive Care, Neonatal, Gestation, Regression Analysis, Female, Original Article, business, Infant, Premature
Abstract

Background: The role of nasal continuous positive airways pressure (nCPAP) in the management of respiratory distress syndrome in preterm infants is not completely defined. Objective: To evaluate the benefits and risks of prophylactic nCPAP in infants of 28–31 weeks gestation. Design: Multicentre randomised controlled clinical trial. Setting: Seventeen Italian neonatal intensive care units. Patients: A total of 230 newborns of 28–31 weeks gestation, not intubated in the delivery room and without major malformations, were randomly assigned to prophylactic or rescue nCPAP. Interventions: Prophylactic nCPAP was started within 30 minutes of birth, irrespective of oxygen requirement and clinical status. Rescue nCPAP was started when FIO2 requirement was > 0.4, for more than 30 minutes, to maintain transcutaneous oxygen saturation between 93% and 96%. Exogenous surfactant was given when FIO2 requirement was > 0.4 in nCPAP in the presence of radiological signs of respiratory distress syndrome. Main outcome measures: Primary end point: need for exogenous surfactant. Secondary end points: need for mechanical ventilation and incidence of air leaks. Results: Surfactant was needed by 22.6% in the prophylaxis group and 21.7% in the rescue group. Mechanical ventilation was required by 12.2% in both the prophylaxis and rescue group. The incidence of air leaks was 2.6% in both groups. More than 80% of both groups had received prenatal steroids. Conclusions: In newborns of 28–31 weeks gestation, there is no greater benefit in giving prophylactic nCPAP than in starting nCPAP when the oxygen requirement increases to a FIO2 > 0.4.

Published
2004

11. Post-discharge nutrition of the very low-birthweight infant: Interim results of the multicentric GAMMA study

Author

Agosti, M., Vegni, C., Calciolari, G., Marini, A., Mautone, A., De Cosmo, L., Ladisa, G., Alessandroni, R., Capretti, A., Chiappe, S., Palmas, G., Polizzi, B., Angrì, F., Catalano, L., Sabatino, G., Domizio, S., Rinaldi, G., Popolo, G., Spennati, G. F., Persia, R., Zanini, R., Bellù, R., Stronati, M., Mussini, P., Ferrari, F., Ferrari, P., Paino, G., Napolitano, M., Spinella, B., Pomo, R., Rondini, G., Polito, E., Lungarotti, S., Soldani, C., Dore, A., Oggiano, R., Mussa, G. C., Farinasso, D., Agosta, G., Saia, S., Battajon, N., Macagno, F., Chiandotto, V., and Leva, L.

Subjects
Psychomotor development, Post-discharge nutrition, 80 kcal/dl formula, VLBWI, Growth, Perinatology and Child Health, Pediatrics, Perinatology and Child Health, Pediatrics
Published
2003

31. Diagnostic imaging in infantile polycystic kidney disease. Presentation of two cases

Author

Beluffi, G., Chiara, A., Fiori, P., Martini, A., ANGELO RAVELLI, and Rondini, G.

Subjects
Male, Polycystic Kidney Diseases, diagnosis, Infant, Newborn, Infant, Humans, Female, Urography, Newborn, Child, Child, Female, Humans, Infant, Newborn, Male, Polycystic Kidney Diseases, diagnosis, Ultrasonography, Urography, Ultrasonography
Published
1987

40. Survival to discharge of a cohort of very low birth weight infants born in Lombardy between 1999-2002

Author

Gagliardi, L., Agosti, M., Barera, G., Caccamo, M. L., Chirico, G., Compagnoni, G., Maccabruni, M., Martinelli, S., Moro, G., Magni, L. A., Mosca, F., Rondini, G., Santucci, S., Tagliabue, P., Zanini, R., roberto bellu', Cavazza, A., Brunelli, A., Battaglioli, M., Tandoi, F., Merazzi, D., Cella, D., Perotti, G. F., Pelti, M., Stucchi, I., Frisone, F., Avanzini, A., Bastrenta, P., Iacono, G., Pontiggia, F., Cotta-Ramusino, A., Strano, F., Fontana, P., Franco, M., Rossi, L., Calciolari, G., Citterio, G., Rovelli, R., Poloniato, A., Gancia, G. P., Costato, C., Germani, R., Barp, S., Crossignani, R., Siliprandi, N., Borroni, C., Ventura, M. L., Abbiati, L., Giardinetti, S., Leva, L., Fusi, M., and Bellasio, M.

Subjects
Life-table analysis, Actuarial survival, Preterm infants, Mortality, Very low birth weight infants, Pediatrics, Perinatology and Child Health, Perinatology and Child Health, Pediatrics

41. Post-discharge nutrition of the very low-birthweight infant: Interim results of the multicentric GAMMA study

Author

Agosti, M., Vegni, C., Calciolari, G., Marini, A., Mautone, A., Cosmo, L., Ladisa, G., Alessandroni, R., Capretti, A., Chiappe, S., Palmas, G., Polizzi, B., Angrì, F., Catalano, L., Sabatino, G., Domizio, S., Rinaldi, G., Popolo, G., Spennati, G. F., Persia, R., Zanini, R., roberto bellu', Stronati, M., Mussini, P., Ferrari, F., Ferrari, P., Paino, G., Napolitano, M., Spinella, B., Pomo, R., Rondini, G., Polito, E., Lungarotti, S., Soldani, C., Dore, A., Oggiano, R., Mussa, G. C., Farinasso, D., Agosta, G., Saia, S., Battajon, N., Macagno, F., Chiandotto, V., and Leva, L.

Subjects
Male, Pediatrics, medicine.medical_specialty, Post discharge, Group B, Corrected Age, Interim, Humans, Infant, Very Low Birth Weight, Medicine, Prospective Studies, Infant Nutritional Physiological Phenomena, Interim report, Psychomotor learning, business.industry, Infant, Newborn, General Medicine, medicine.disease, Infant Formula, Patient Discharge, Head circumference, Pediatrics, Perinatology and Child Health, Small for gestational age, Female, business, very low birth wieight, Psychomotor Performance
Abstract

This report presents the interim results up to 12 mo corrected age (c.a.) of a multicentric, prospective, controlled study on very low-birthweight infants, randomized at 40 wk post-conception in two different groups of formula feeding: 80 Kcal/dL (group A) vs 70 Kcal/dL (group B) up to 55 wk of postconceptional age. Subsequently, all the babies were fed with a follow-on formula, with the introduction of solid foods at 6 mo c.a. Weight, length, head circumference and neurological conditions with psychomotor development (evaluated by the Griffiths' Developmental Scale) were measured at regular intervals and all of these parameters were satisfactory in both groups. For growth, in group A there was a greater increase in weight in boys at 55 wk and at 6 mo c.a., and small for gestational age (SGA) babies had a greater increase in length at 1 y of age, while head circumference caught up on growth from week 40 to week 55. Measured by the Griffiths' Developmental Scale, the SGA group fed 80 Kcal/dL had a better score at 6 mo; similarly boys fed 80 Kcal/dL had a better score at 6 and at 9 mo. Conclusion: Nutrition of very low birthweight infants post-discharge could have an influence on physical growth and on neurodevelopmental outcome. This interim report needs to be confirmed at the end of the study.

46. HEPATITIS-B IMMUNIZATION IN INFANTS OF HEPATITIS-B SURFACE ANTIGEN-NEGATIVE MOTHERS

Author

Chirico, G., Belloni, C., Gasparoni, A., Cerbo, Rm, Rondini, G., Catherine Klersy, Orsolini, P., and Filice, G.

Subjects
Male, Hepatitis B Surface Antigens, Logistic Models, Pediatrics, Perinatology and Child Health, Infant, Newborn, Humans, Female, Hepatitis B Vaccines, Hepatitis B Antibodies, Hepatitis B, Immunization Schedule
Abstract

The American Academy of Pediatrics (AAP) Committee on Infectious Diseases and the Immunization Practices Advisory Committee of the Centers for Disease Control have recently pointed out that the selective strategy of immunization against hepatitis B virus (HBV) of high-risk populations has not resulted in the limitation of the diffusion of the disease. In fact, in spite of vaccine availability for more than 10 years, about 200 000 to 300 000 new cases of infection occur in the United States each year. Therefore, the AAP recommended the "universal hepatitis B immunization" strategy as a means to control the disease.1,2 In Italy, where about 400 000 new cases of infection are expected each year, the vaccination has been extended to all newborns, regardless of mother's serologic status (and, for the first 12 years, to all 12-year-old adolescents), with a law promulgated in May 1991.

50. Bacteriological and clinical efficacy of various antibiotics used in the treatment of streptococcal pharyngitis in Italy. An epidemiological study

Author

G Rondini, M. Cianflone, L. Santini, Clementina Cocuzza, Roberto Mattina, A. Lanzafame, Rondini, G, Cocuzza, C, Cianflone, M, Lanzafame, A, Santini, L, and Mattina, R

Subjects
Microbiology (medical), Josamycin, Adolescent, Streptococcus pyogenes, β-lactam, Streptococcus pyogene, Microbial Sensitivity Tests, Penicillins, medicine.disease_cause, Streptococcal pharyngitis, Article, Microbiology, Clarithromycin, Streptococcal Infections, Anti-Bacterial Agent, medicine, Humans, Pharmacology (medical), Child, business.industry, Microbial Sensitivity Test, Spiramycin, Clindamycin, Drug Resistance, Microbial, Pharyngitis, General Medicine, MED/38 - PEDIATRIA GENERALE E SPECIALISTICA, Penicillin, Anti-Bacterial Agents, Erythromycin, Infectious Diseases, Italy, MED/07 - MICROBIOLOGIA E MICROBIOLOGIA CLINICA, Child, Preschool, Pharynx, medicine.symptom, business, Rokitamycin, medicine.drug
Abstract

A total of 123 community paediatricians and 23 microbiology laboratories studied the clinical and bacteriological efficacy of treatment of group A streptococcal pharyngitis in Italy. Of 1065 patients, from whom Streptococcus pyogenes was isolated, 723 returned to follow up and of these 138 (19%) still had a positive throat culture. The erythromycin resistance (ER) rate was 23.7% with resistance phenotype distribution of: 31.7% constitutive (CR), 26.6% inducible (IR) and 41.7% efflux pump (M) resistance phenotype. All strains were susceptible to the β-lactam agents tested. CR strains were highly resistant to all 14, 15 and 16 membered macrolides with the exception of rokitamycin which showed activity against 37.8% of isolates. All phenotype M and some IR isolates were susceptible to clindamycin, rokitamycin, josamycin and spiramycin; clarithromycin was active against a small percentage of strains belonging to the IR and M phenotype. Bacterial eradication was found in 85.5, 78.7 and 75.8% of the penicillin, macrolide and cephalosporin treated groups. Genotyping of strains showed that 8.7% of the 19% of cases classified as ‘failed bacterial eradication’ were due to recolonization with a different isolate, observed exclusively among β-lactams treated patients. Clinical cure was achieved in a high percentage of cases, irrespective of the antibiotic prescribed, with the best clinical efficacy being found following therapy with amoxycillin and clarithromycin (90.9%).

Published
2001

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